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Merge rust-toolbox into this repo. #372
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Commits on Mar 9, 2021
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add invalidated_umis to ContigAnnotation
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Commits on Mar 12, 2021
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fix bug in parse_csv if comma at end
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Commits on Mar 13, 2021
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prevent multiple threads from issuing tracebacks
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Commits on Mar 23, 2021
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Update bio dependency to 0.33. (#48)
Rather than a git revision. vdj_ann should depend on published align_tools.
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Commits on Apr 13, 2021
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try to fix but in vis_align (#49)
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Commits on Apr 26, 2021
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vis_align now takes a Vec<AlignmentOperation> as input
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align_tools version now known as 0.1
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Commits on May 4, 2021
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improve internal error handling in print_vis_align
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Commits on Jun 4, 2021
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blacklist tokio and future in tracebacks
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blacklist two more things in pretty_trace
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Commits on Jun 16, 2021
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add ability to run a function before exiting
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move elapsed time info and bump version
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Commits on Jul 9, 2021
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update crates / broaden ranges, nearly equivalent to Adam's PR #56
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Commits on Jul 24, 2021
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add modified and subsetted version of bio crate
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Commits on Aug 10, 2021
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Upgrade to GitHub-native Dependabot (#50)
* Upgrade to GitHub-native Dependabot * Remove ignores. Co-authored-by: dependabot-preview[bot] <27856297+dependabot-preview[bot]@users.noreply.github.com> Co-authored-by: Adam Azarchs <adam.azarchs@10xgenomics.com>
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David Jaffe committed
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Commits on Sep 13, 2021
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Commits on Sep 30, 2021
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Bump rust edition to 2018. (#69)
* Bump rust edition to 2018. * Remove unused dependencies. * Deny warnings in CI, and add clippy check. * Automated clippy fix. * Fix future-incompatible macro warning. semicolon-in-expressions-from-macros * Fix clippy errors. Remove redundant if cases. Use `if let Some(x) = y.next()` rather than a loop-and-break. Don't clone something when cloning doesn't do anything.
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Add include directives to Cargo.tomls
These directives control which files are downloaded when someone gets the crate from crates.io. It is good practice to exclude test files, READMEs, and so on in order to minimize the download. The main impact of this is on the 50+mb of fasta files in vdj_ann, but there's also a relatively large jpg image for pretty_trace.
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Commits on Oct 1, 2021
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Replace
failure
with specific errorsReplace the `failure::Error` usage with the concrete (and only) errors for each case. For `pretty_trace` and `binary_vec_io` I used the errors from `std::io::Error` and `nix::Error` directly.
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Commits on Oct 10, 2021
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update master.toml to reflect actual usage
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do not specify z versions for crates in this workspace
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fix value(...) in mirror_sparse_matrix, which returned wrong answer i…
…f > 2^16 - 1 (#70)
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Commits on Oct 13, 2021
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Clippy should never be blanket-disabled. The deny-level lints are generally indicating a serious problem, or at least a high likelihood that the code is confusing. In cases where it is overly aggressive, it's reasonable to disable specific lints, but only one at a time.
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Forbid clippy::unused_io_amount.
We've had several production bugs because of this one.
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Move bundled fasta files to a separate crate.
It's not great to make the linker process 25MB of fasta files unless it's actually required. Also move the binaries, with their dependency on exons (which shouldn't have been published, but too late now...).
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Merge pull request #73 vdj_ann fixups.
Move embedded reference data out of vdj_ann.
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Commits on Oct 18, 2021
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add peak memory function for mac (#74)
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Commits on Oct 29, 2021
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tools for working with eval_expr (#76)
This is an initial, minimal toolkit for working with eval_expr, and used by enclone. It is unstable at the moment.
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Commits on Oct 31, 2021
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vars_of_node now unique sorts its result
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Commits on Nov 2, 2021
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raise pprof version from 0.5 to 0.6
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Commits on Nov 9, 2021
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Commits on Nov 12, 2021
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* added Gamma and Delta * some formatting changes * fixing changes to yml file
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Fix a future-incompatible warning in some `io_util` macros due to trailing semicolons. Also fix those macros to work properly when expanded in contexts where the types they're accessing aren't in scope, and allow them to work with `impl AsRef<Path>` types rather than just `&String`. Add trait implementations where appropriate, mostly `Default` but also a few for `From` where it looked like it made sense given existing conversion functions, in order to bring the APIs into conformance with common naming conventions. Fix a bunch of clippy lints around stuff that looks like ```rust if f.is_err() { // thing } else { let f = f.unwrap(); // other thing } ``` using `match` instead to avoid checking more than once whether the type was an error. Replace uses of `&Vec<T>` with `&[T]` where possible. In some cases, the extent to which this was possible is limited until some of the upstream crates (from this repository) push a new version with their APIs updated. Replace uses of `&String` with either `&str` or `impl AsRef<Path>` as appropriate for the use case. Again, as with the `&Vec<T>` changes, in some cases this means temporarily going through fallible steps allocating String objects until the upstream crates publish versions with updated APIs. I could be wrong but I believe that `cargo clippy --fix` will be able to fix the TODOs from the above two items automatically when the time comes. The above two changes _shouldn't_ affect existing users, at least in most cases (`&Vec<T>` casts implicitly to `&[T]`, `&String` casts implicitly to `&str`, and both `&String` and `&str` implement `AsRef<Path>`). At least, in theory. Change the `segtype` field of `vdj_ann::refx::RefData` from a vector of owned `String` to a `&'static str`, since everything added to that vector is a constant value. This should significantly reduce memory consumption, as the vector is now a vector of pointers into constant memory rather than a vector of pointers each into their own heap- allocated copy of the source strings. Because that field is public, this is a breaking API change (though I don't know how many downstream users actually access the field directly), so I'm bumping the version of that crate. In vdj_ann_ref, don't convert `&'static str` to `String` except in cases where (similarly to above) we have to in order to satisfy the old APIs. Also, change the if-chaining logic to `match` statements to make the different cases more clear.
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Bump io_utils for crates which depend on it. (#79)
* Bump depended-on version for io_utils. * Remove unused imports. * Fix TODOs from #78.
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Commits on Nov 14, 2021
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Revert "Nmmsv/gd chains (#77)" -- changes results in enclone
This reverts commit df785d5.
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Commits on Nov 17, 2021
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catch condition that would cause assert (#80)
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Update num-bigint, num-rational in stirling_numbers.
These are dev dependencies, but they were conflicting with the versions expected by nalgebra.
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Widen version range for petgraph.
Hyperbase must use the same version as whatever version its graph_simple dependency uses, but that's allowed with the widened version range.
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Remove unnecessary #[allow()] annotations.
Also fix some clippy lints.
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Update test.yml to ignore some lints.
many_single_char_names and comparison_chain are both too noisy, at least for now, and it would be better to focus on more important ones like ptr_arg. On the other hand, deny `unused` and `perf` lints.
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Set permissions for test workflow.
This should allow dependabot PRs to succeed.
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David Jaffe committed
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Merge pull request #84 from 10XGenomics/nmmsv/new-gamma-delta-support
add support for gamma_delta
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Commits on Dec 16, 2021
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`DnaString.get`needs to unpack a k-mer, which requires the following: 1 - Translate index to byte-block and position within block. 2 - Unpack the relevant value from a byte and return. The array bounds check on unpacking the byte seems to take around 5% of the profile, and could be a lot more due to interference with pipelining.
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Merge pull request #87 from 10XGenomics/nd/cached_seq
Unpack Query Sequence Prior to Processing
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Commits on Dec 22, 2021
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This also only warns for clippy::vec_init_then_push because doing what it requests would make the code less clear (for the particular cases at issue).
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make vdj_ann_ref point to crates.io version of vdj_ann
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Commits on Jan 6, 2022
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* Re-enable denying performance-relevant clippy checks. Also fix hard-to-read code in vdj_features, and some other performance issues there. * cargo clippy --fix * More random cleanups. * Update CI rust version to 1.57.0.
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Commits on Jan 21, 2022
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1. bump eval_expr from 6 to 7 2. lower crate version specificity 3. bump versions of affected crates
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Commits on Jan 27, 2022
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put Cargo.lock under source code control
The reason for doing this is that someone needs to be able to check out the repo and build it. That requires a working Cargo.lock, and the person should not have to make it work from scratch. Currently the repo does not build.
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David Jaffe committed
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David Jaffe committed
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David Jaffe committed
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David Jaffe committed
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Commits on Feb 4, 2022
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Extensive changes to annotate_seq_core and one additional reference sequence add (IGHV3-9), which affect around 2% of cells, and significantly improve the alignments for these. These changes are technical tweaks to the aligner. To measure and drive these changes, the enclone program diff_enclone_ann was used. diff_enclone_ann BIB=1 OLD_EXEC=~/enclone.old changed cells = 2084 old dref sum = 61522 new dref sum = 38645 improvement = 22877 cells lost by old = 6 cells lost by new = 11 diff_enclone_ann BIB=2 OLD_EXEC=~/enclone.old changed cells = 584 old dref sum = 28173 new dref sum = 22168 improvement = 6005 cells lost by old = 4 cells lost by new = 6 and what this is saying is that observed SHM (as measured by the variable `dref`) is significantly reduced. This is because a bunch of bad alignments were cleaned up, thereby removing "fake" SHM. The changes removed some donor reference anomalies, in which highly modified donor reference sequences were found. The changes made enclone BUILT_IN ... about 3.7% slower, when run using a single thread. These changes also resulted in a modest improvement to clonotyping sensitivity and specificity.
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David Jaffe committed
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fix to Cargo.toml and bump version
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fix bug in calls to is_v(t) in annotate_seq_core (#103)
These needed to be shielded to avoid "segments".
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Commits on Feb 7, 2022
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remove near identical transcripts and switch from "release" to "debug" (
#104) 1. If two transcripts are identical except that one extends the other on the 3' end, delete the shorter one. 2. Switch to a standard model in which debug mode is optimized.
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add TRGC genes for mouse (#105)
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add the old ref and access to it
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fix TRGCC (should be TRGC) and add in some missing TRGV genes
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Commits on Feb 14, 2022
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fix bug in read_fasta_to_vec_vec_u8 that was introduced somehow
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Disable clippy::needless_range_loop check. (#112)
It's much too noisy. Fix a missing documentation lint by expanding on the ways in which resize_without_setting is unsafe, and also demote a clippy warning from inside it. Fix a bunch of clippy warnings (some automatic fixes, some manual).
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Commits on Feb 23, 2022
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Add path = ../... for interdependencies. (#113)
This is in addition to the existing version constraint, which is required for publishing. It allows for much easier development when working on changes which cut across several crates, as well as faster builds due to not building crates multiple times. Also add a cargo-deny config to check for accidental introduction of duplicated dependencies, dependencies with unacceptable licenses, or dependencies with known security vulnerabilities.
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Commits on Mar 10, 2022
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delete five duplicate genes from the human VDJ reference (#116)
Delete the following genes from the human VDJ reference: IGHV4-30-2, IGKV1D-33, IGKV1D-37, IGKV1D-39, IGKV2D-28. These are identical to other genes in the reference, except that the reference provides a longer 5'-UTR in one case. We observe that clonotypes having one of these genes often have heterogeneous assignments between the gene and its duplicate, and that's bad, as it implies that assignment of genes to clonotypes in these cases is effectively random. Also cargo update -p regex to get CI to pass.
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Commits on Apr 12, 2022
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update permutation crate (#128)
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Commits on Apr 15, 2022
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try to fix a windows compilation problem involving binary_read_to_ref (…
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fix windows compilation problem (#133)
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fix another windows compilation problem (#134)
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fix windows compilation problem (#135)
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DJ authored
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Commits on Apr 16, 2022
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Fix some new clippy lints. Reduce unnecessary String allocations.
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It's quite a bit faster, because we were on v1 before and v2 switched to zstd compression. Add dependabot config to keep our actions updated in the future.
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fix to a fix for Windows (#140)
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Commits on May 17, 2022
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Bump libc from 0.2.119 to 0.2.126
Bumps [libc](https://github.com/rust-lang/libc) from 0.2.119 to 0.2.126. - [Release notes](https://github.com/rust-lang/libc/releases) - [Commits](rust-lang/libc@0.2.119...0.2.126) --- updated-dependencies: - dependency-name: libc dependency-type: direct:production update-type: version-update:semver-patch ... Signed-off-by: dependabot[bot] <support@github.com>
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Update CI rust, as well as some packages.
Permit update of pprof and nix versions.
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Commits on Jul 25, 2022
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Bump num-rational from 0.4.0 to 0.4.1 (#160)
Bumps [num-rational](https://github.com/rust-num/num-rational) from 0.4.0 to 0.4.1. - [Release notes](https://github.com/rust-num/num-rational/releases) - [Changelog](https://github.com/rust-num/num-rational/blob/master/RELEASES.md) - [Commits](rust-num/num-rational@num-rational-0.4.0...num-rational-0.4.1) --- updated-dependencies: - dependency-name: num-rational dependency-type: direct:production update-type: version-update:semver-patch ... Signed-off-by: dependabot[bot] <support@github.com> Co-authored-by: dependabot[bot] <49699333+dependabot[bot]@users.noreply.github.com>
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Bump serde_json from 1.0.81 to 1.0.82 (#162)
Bumps [serde_json](https://github.com/serde-rs/json) from 1.0.81 to 1.0.82. - [Release notes](https://github.com/serde-rs/json/releases) - [Commits](serde-rs/json@v1.0.81...v1.0.82) --- updated-dependencies: - dependency-name: serde_json dependency-type: direct:production update-type: version-update:semver-patch ... Signed-off-by: dependabot[bot] <support@github.com> Co-authored-by: dependabot[bot] <49699333+dependabot[bot]@users.noreply.github.com>
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Bump serde from 1.0.137 to 1.0.140 (#169)
Bumps [serde](https://github.com/serde-rs/serde) from 1.0.137 to 1.0.140. - [Release notes](https://github.com/serde-rs/serde/releases) - [Commits](serde-rs/serde@v1.0.137...v1.0.140) --- updated-dependencies: - dependency-name: serde dependency-type: direct:production update-type: version-update:semver-patch ... Signed-off-by: dependabot[bot] <support@github.com> Co-authored-by: dependabot[bot] <49699333+dependabot[bot]@users.noreply.github.com>
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Bump permutation from 0.4.0 to 0.4.1 (#170)
Bumps [permutation](https://github.com/jeremysalwen/rust-permutations) from 0.4.0 to 0.4.1. - [Release notes](https://github.com/jeremysalwen/rust-permutations/releases) - [Commits](https://github.com/jeremysalwen/rust-permutations/commits) --- updated-dependencies: - dependency-name: permutation dependency-type: direct:production update-type: version-update:semver-patch ... Signed-off-by: dependabot[bot] <support@github.com> Co-authored-by: dependabot[bot] <49699333+dependabot[bot]@users.noreply.github.com>
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Commits on Sep 12, 2022
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Loosen type constraints on bin_possition etc.
They now permit e.g. searching a &[String] for a &str, rather than requiring a &String for the search parameter. The requirement is that the type in the slice implements Borrow<T> (for which there is a blanket implementation `borrow(&T) -> &T`). This is a backwards-compatible change except in so far as it may alter the compiler's ability to infer types in some weird cases which are probably bugs anyway.
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Commits on Nov 23, 2022
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Commits on Nov 24, 2022
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Switch to 10XGenomics fork of clippy-check
The upstream actions-rs/clippy-check is unmaintained.
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Commits on Nov 25, 2022
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Fix new clippy lints. Update to maintained github actions.
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Shamoni Maheshwari committed
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Merge pull request #240 from 10XGenomics/sm/update_contig_annotations
Add junction_support field to ContigAnnotation
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Make fields of JunctionSupport pub
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Merge pull request #241 from 10XGenomics/sm/make_fields_public
Make fields of JunctionSupport pub
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chore: Delete stale travis-ci file.
Looks like this was an editor state file that was left around.
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Commits on Jun 22, 2023
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Bump itertools from 0.10.5 to 0.11.0 (#260)
Bumps [itertools](https://github.com/rust-itertools/itertools) from 0.10.5 to 0.11.0.
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build(deps): Update Cargo.lock
Hold back to versions - thiserror 1.0.39 - serde 1.0.156 to stay on syn 1.0.109
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Merge pull request #261 from 10XGenomics/sj/bio-types
build(deps): bump bio-types from 0.13.0 to 1.0.0
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Commits on Sep 11, 2023
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Add an optional sample field to ContigAnnotation
Shamoni Maheshwari committedSep 11, 2023 Configuration menu - View commit details
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Merge pull request #290 from 10XGenomics/sm/add_sample_field
Add an optional sample field to ContigAnnotation
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build(deps): Update Rust dependencies (#295)
Package Before After aho-corasick 1.0.2 1.1.1 anyhow 1.0.71 1.0.75 bio-types 1.0.0 1.0.1 bytemuck 1.13.1 1.14.0 bytes 1.4.0 1.5.0 cc 1.0.79 1.0.83 cpp_demangle 0.4.1 0.4.3 cpufeatures 0.2.8 0.2.9 crossbeam-epoch 0.9.13 0.9.15 either 1.8.1 1.9.0 errno 0.3.1 0.3.4 fastrand 1.9.0 2.0.1 hashbrown 0.14.0 0.14.1 indexmap 2.0.0 2.0.2 itoa 1.0.6 1.0.9 linux-raw-sys 0.3.8 0.4.8 log 0.4.19 0.4.20 matrixmultiply 0.3.7 0.3.8 memchr 2.5.0 2.6.4 memoffset 0.7.1 0.9.0 num-complex 0.4.3 0.4.4 paste 1.0.12 1.0.14 quote 1.0.28 1.0.33 rayon 1.7.0 1.8.0 rayon-core 1.11.0 1.12.0 regex 1.8.4 1.9.6 regex-syntax 0.7.2 0.7.5 rustix 0.37.20 0.38.15 rustversion 1.0.12 1.0.14 ryu 1.0.13 1.0.15 safe_arch 0.7.0 0.7.1 scopeguard 1.1.0 1.2.0 sha2 0.10.7 0.10.8 smallvec 1.10.0 1.11.1 strum_macros 0.24.3 0.25.2 symbolic-common 12.2.0 12.4.1 symbolic-demangle 12.2.0 12.4.1 tempfile 3.6.0 3.8.0 thiserror 1.0.39 1.0.49 thiserror-impl 1.0.39 1.0.49 typenum 1.16.0 1.17.0 unicode-ident 1.0.1 1.0.12 uuid 1.3.4 1.4.1 which 4.4.0 4.4.2 wide 0.7.10 0.7.12 windows-targets 0.48.0 0.48.5 windows_aarch64_gnullvm 0.48.0 0.48.5 windows_aarch64_msvc 0.48.0 0.48.5 windows_i686_gnu 0.48.0 0.48.5 windows_i686_msvc 0.48.0 0.48.5 windows_x86_64_gnu 0.48.0 0.48.5 windows_x86_64_gnullvm 0.48.0 0.48.5 windows_x86_64_msvc 0.48.0 0.48.5
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Commits on Jan 23, 2024
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Fix overflow bugs in VDJ FR3 start identification. (#316)
Consistently handle FR3 start window bounds in the face of sequences that are possibly shorter than the window we're searching in. Bail out early if the full search window does not overlap with the sequence, to ensure that the FR3 start computed based on a given contig is the same irrespective of the amount of prefix clipped in the contig.
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Commits on Feb 21, 2024
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