2p-Olfactory-Code-Analysis

Collaborated work by Kaining Zhang, Pingchuan Ma, Binxu Wang

Trial structure

Trial structure : for each stimuli 40ms before start, 15ms during stimuli, 60ms after stimuli.

TODO List

• Examine the Odor and their natural functions

  • Odor and their receptor and their pathway
  • EA, EB, MH are similar chemical (ester) is food odor
  • 1-octen-3-ol
  • Bzald (Benzaldehyde), Acet (Acetophenone)

• Response matrix

• draw a distribution of the responsive neuron on z axis.

• Matrix factorization

  • SVD (KN)
  • Non negative matrix factorization (NMF) (BX)

• classify neuron based on their response to stimulus.

  • Hierachical clustering??? (based on distance) (BX)
  • K means (On response/off response ; PCA Dimension reduction ) (KN)
  • Plot cluster distribution on z axis

• Draw the neurons population trajectory to the stimuli.(have done) (KN)

  • SVD
  • LLE / Other non linear dimension reduction

• Background research

  • Anatomical location
  • connectivity ~ Antennal lobe, Mushroom Body
    • Laminar structure?????
  • Computational function??????? (Expansion / compression????)
  • Function in sensory transformation ?

Spatial Temporal Structure of Lateral Horn Input