diff --git a/README.md b/README.md
index e40e0c0..f2ba0d1 100644
--- a/README.md
+++ b/README.md
@@ -5,6 +5,7 @@ Contributions to the collection are very welcome. For this, please create a new
 
 ## Overview
 
+<!-- START OVERVIEW TABLE -->
 | PEtab Problem ID                                                                             |   Conditions |   Estimated Parameters |   Events |   Preequilibration |   Postequilibration |   Measurements |   Observables | Noise distribution(s)   |   Species | References                                                                                                                                                                                 | SBML4Humans                                                                                                                                                                                                                              |
 |:---------------------------------------------------------------------------------------------|-------------:|-----------------------:|---------:|-------------------:|--------------------:|---------------:|--------------:|:------------------------|----------:|:-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|:-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
 | [Alkan_SciSignal2018](Benchmark-Models/Alkan_SciSignal2018/)                                 |           73 |                     56 |        0 |                  0 |                   0 |           1733 |            12 | normal                  |        36 | [\[1\]](http://identifiers.org/doi/10.1126/scisignal.aat0229)                                                                                                                              | [\[1\]](https://sbml4humans.de/model_url?url=https://raw.githubusercontent.com/Benchmarking-Initiative/Benchmark-Models-PEtab/master/Benchmark-Models/Alkan_SciSignal2018/model_Alkan_SciSignal2018.xml)                                 |
@@ -39,7 +40,7 @@ Contributions to the collection are very welcome. For this, please create a new
 | [Weber_BMC2015](Benchmark-Models/Weber_BMC2015/)                                             |            2 |                     36 |        0 |                  1 |                   0 |            135 |             8 | normal                  |         7 | [\[1\]](http://identifiers.org/doi/10.1186/s12918-015-0147-1)                                                                                                                              | [\[1\]](https://sbml4humans.de/model_url?url=https://raw.githubusercontent.com/Benchmarking-Initiative/Benchmark-Models-PEtab/master/Benchmark-Models/Weber_BMC2015/model_Weber_BMC2015.xml)                                             |
 | [Zhao_QuantBiol2020](Benchmark-Models/Zhao_QuantBiol2020/)                                   |            7 |                     28 |        0 |                  0 |                   0 |             82 |             1 | normal                  |         5 | [\[1\]](http://identifiers.org/pubmed/32219006)                                                                                                                                            | [\[1\]](https://sbml4humans.de/model_url?url=https://raw.githubusercontent.com/Benchmarking-Initiative/Benchmark-Models-PEtab/master/Benchmark-Models/Zhao_QuantBiol2020/SBML_Zhao_QuantBiol2020.xml)                                    |
 | [Zheng_PNAS2012](Benchmark-Models/Zheng_PNAS2012/)                                           |            1 |                     46 |        0 |                  1 |                   0 |             60 |            15 | normal                  |        15 | [\[1\]](http://identifiers.org/doi/10.1073/pnas.1201240109)                                                                                                                                | [\[1\]](https://sbml4humans.de/model_url?url=https://raw.githubusercontent.com/Benchmarking-Initiative/Benchmark-Models-PEtab/master/Benchmark-Models/Zheng_PNAS2012/model_Zheng_PNAS2012.xml)                                           |
-
+<!-- END OVERVIEW TABLE -->
 
 ## License
 
diff --git a/scripts/_helpers.py b/scripts/_helpers.py
index ee3b9a0..12d56f5 100644
--- a/scripts/_helpers.py
+++ b/scripts/_helpers.py
@@ -1,10 +1,12 @@
 from pathlib import Path
 
 
-benchmark_path = Path(__file__).parent.parent / 'Benchmark-Models'
+benchmark_path = Path(__file__).resolve().parent.parent / 'Benchmark-Models'
 petab_yamls = {
     petab_path.name: benchmark_path / petab_path.name / (petab_path.name + '.yaml')
     for petab_path in benchmark_path.glob('*')
     if petab_path.name != '.DS_Store'
 }
 petab_yamls = {k: petab_yamls[k] for k in sorted(petab_yamls)}
+
+readme_md = Path(__file__).resolve().parent.parent / "README.md"
diff --git a/scripts/overview.py b/scripts/overview.py
index a470858..9b27e1e 100755
--- a/scripts/overview.py
+++ b/scripts/overview.py
@@ -9,7 +9,7 @@
 import pandas as pd
 import petab
 
-from _helpers import petab_yamls
+from _helpers import petab_yamls, readme_md
 
 
 markdown_columns = {
@@ -145,8 +145,12 @@ def get_overview_table() -> pd.DataFrame:
     return df
 
 
+start_overview_table = '\n<!-- START OVERVIEW TABLE -->\n'
+end_overview_table = '\n<!-- END OVERVIEW TABLE -->\n'
+
 def main(
-        markdown: bool = False,
+    markdown: bool = False,
+    update_readme: bool = False,
 ):
     df = get_overview_table()
     pd.options.display.width = 0
@@ -163,7 +167,24 @@ def main(
             )
         df.index.rename(markdown_columns[index_column], inplace=True)
         df.rename(columns=markdown_columns, inplace=True)
-        print(df.to_markdown())
+        markdown_overview = df.to_markdown()
+        if update_readme:
+            with open(readme_md, "r") as f:
+                readme_content = f.read()
+                before_table = readme_content.split(start_overview_table)[0]
+                after_table = readme_content.split(end_overview_table)[1]
+                new_readme_content = (
+                    before_table
+                    + start_overview_table
+                    + markdown_overview
+                    + end_overview_table
+                    + after_table
+                )
+            with open(readme_md, "w") as f:
+                f.write(new_readme_content)
+        else:
+            print(markdown_overview)
+
     else:
         print(df)
 
@@ -172,6 +193,10 @@ def main(
     import sys
 
     markdown = False
+    update_readme = False
     if '--markdown' in sys.argv:
         markdown = True
-    main(markdown)
+    if '--update' in sys.argv:
+        markdown = True
+        update_readme = True
+    main(markdown=markdown, update_readme=update_readme)