基于基因治疗的睾丸-卵巢药物转化研究.md

基于敲除FoXL/Sox9基因的药物试制

基因敲除得到性转小鼠

https://ac.els-cdn.com/S0092867409014949/1-s2.0-S0092867409014949-main.pdf?_tid=59f7e45a-8790-4dd2-a601-0216ffa49f72&acdnat=1532799684_41c4b06fd130a7cea4963524f9776e6c
https://ac.els-cdn.com/S0092867409014330/1-s2.0-S0092867409014330-main.pdf?_tid=798af3b3-27ed-48e9-8635-b520496d67a1&acdnat=1532799742_117f3d19d142625f88b33abb6e3e6244
https://ac.els-cdn.com/S0960982215000664/1-s2.0-S0960982215000664-main.pdf?_tid=dc23022f-a714-461a-be4d-69b4d79968c9&acdnat=1532799814_8ec63bf814fec8c9d98e11b2bb294825
https://ac.els-cdn.com/S1934590912004778/1-s2.0-S1934590912004778-main.pdf?_tid=ea2247d8-fd6c-4c99-9a92-3969805f03f3&acdnat=1532799854_1802fd8e1b51ee77828bb7f25b3cabf3
https://ac.els-cdn.com/S0012160616300707/1-s2.0-S0012160616300707-main.pdf?_tid=7dd400e0-7b16-47aa-b71e-5c9fe29ce410&acdnat=1532799892_1c0c34f6f7e1220ea1cef7312016d109
https://ac.els-cdn.com/S0012160615302864/1-s2.0-S0012160615302864-main.pdf?_tid=a625b8c1-99bd-4aa9-ad44-4a3aa99afe88&acdnat=1532799949_4ea64bc83ed53bf02a0a730b779bb170
https://ac.els-cdn.com/S0960982213015984/1-s2.0-S0960982213015984-main.pdf?_tid=b4026c2d-9114-4e8c-b16a-74ee27066782&acdnat=1532799972_e4e952012901aaff1241c0b491bfbbe0

成体进行基因治疗

https://ac.els-cdn.com/S0960982213015984/1-s2.0-S0960982213015984-main.pdf?_tid=b4026c2d-9114-4e8c-b16a-74ee27066782&acdnat=1532799972_e4e952012901aaff1241c0b491bfbbe0
敲HIV的：https://www.uclahealth.org/care-center/gene-therapy-studies

UCLA的 Funding

https://stemcell.ucla.edu/news?tid=8