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Third data release (2023)

Consolidated release, now including data from both fetuses and neonates

1. Cohort

• Neonatal participants: 783 subjects (886 datasets).
• Fetal participants: 273 subjects (297 datasets).

2. MR Imaging data

• Native and processed. Structural, DTI, fMRI.

3. Clinical information about pregnancy and birth

• Pregnancy: Data include previous obstetric history, pre-pregnancy and antenatal maternal conditions, medication. • Birth: data include gestational age at birth, birth weight, length, and head circumference, presentation and mode of birth, medication required at delivery, nutrition and feeding, apgar scores at 1 and 5 min of age. For babies that were admitted to the intensive care unit, there are clinical details about their stay.

4. Genomics

• Saliva-derived DNA sample were genotyped for single-nucleotide polymorphisms and also processed for methylation analysis.

5. Eye-tracking data at 18 months of age

• Visual attention metrics

Upcoming data (pending NDA approval):

• Neurodevelopmental outcome at 18 months of age.

HOW TO ACCESS AND DOWNLOAD THE DATA:

All data are available from the NDA website NDA website. The NDA is responsible for all data governance. Instructions for how to access and download the data can be found:

Updated guidelines - download from NDA

Feedback

We invite colleagues in the field to explore and feedback on the value and characteristics of the image dataset. The image data have been processed using analysis pipelines that are subject to further development. If you use this data or the pipelines please cite the appropriate publications as detailed in the How to cite notes.

Acknowledgments

The research leading to these data has received funding from the European Research Council under the European Union Seventh Framework Programme (FP/20072013)/ERC Grant Agreement no. 319456. The work was also supported by the NIHR Biomedical Research Centres at Guys and St Thomas NHS Trust. We are grateful to the families who generously supported this trial. We would like to acknowledge Core support for data acquisition was provided by the Wellcome/EPSRC Centre for Medical Engineering [WT 203148/Z/16/Z]. We are also thankful to the WU-Minn-Oxford Human Connectome Project consortium (1U54MH091657-01) for access to their computing resources.