EPNClassifier assigns molecular groups to ependymal tumors profiled by bulk transcriptomics (RNA-seq or microarrays). It is based on gene set enrichment analysis of pre-determined gene signatures from Pajtler K.W. et al., Cancer Cell 27 (2015) and Pajtler K.W. et al., Acta Neuropathol 136 (2018). Significant p-values can be used to classify EPN tumors into their most-likely molecular subgroup. PFA tumors can be further classified into subtypes (PFA_1 and PFA_2).