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We investigated circulating levels of brain injury, inflammation, and vascular biomarkers in a cohort of Plasmodium knowlesi-infected patients and uninfected, healthy controls in Peninsular Malaysia.

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Cescualito/LSHTM_Wassmer_Pknowlesi_Malaysia

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LSHTM_Wassmer_Pknowlesi_Malaysia

We investigated circulating levels of brain injury, inflammation, and vascular biomarkers in a cohort of Plasmodium knowlesi-infected patients and uninfected healthy controls from Peninsular Malaysia.

Published version available in JID with DOI: 10.1093/infdis/jiae553

Study collaborators

Cesc Bertran-Cobo, Elin Dumont, Naqib Rafieqin Noordin, Meng-Yee Lai, William Stone, Kevin KA Tetteh, Chris Drakeley, Sanjeev Krishna, Yee Ling Lau, Samuel C Wassmer. Correspondence to Prof Dr Yee Ling Lau, Universiti Malaya, Kuala Lumpur, Malaysia (lauyeeling@um.edu.my) and Dr Samuel C Wassmer, London School of Hygiene and Tropical Medicine, London, UK (Sam.Wassmer@lshtm.ac.uk).

Repository contents

Pk_Malaysia_analysis.R contains the complete R code used for conducting the entire study analysis. It includes data preprocessing, statistical tests, and data visualization steps.

Pk_Malaysia_analysis.Rmd contains the complete R markdown code used to create an HTML report of the statistical analysis.

Pk_Malaysia_report.html presents the interactive analysis and results generated from the study's data using the accompanying .Rmd script. Readers can explore the report to gain a thorough understanding of the study's methodology, results, and implications. The codebook is included here.

Pk_Malaysia_map contains an interactive map of sample collection sites in Peninsular Malaysia.

Publication link

The published version can be found here. The original manuscript can be found here.

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We investigated circulating levels of brain injury, inflammation, and vascular biomarkers in a cohort of Plasmodium knowlesi-infected patients and uninfected, healthy controls in Peninsular Malaysia.

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