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DESCRIPTION
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DESCRIPTION
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Package: methrix
Title: Fast and efficient summarization of generic bedGraph files from Bisufite sequencing
Version: 1.8.01
Authors@R: c(
person("Anand","Mayakonda", role = c("aut", "cre"), email = "anand_mt@hotmail.com", comment = c(ORCID = "0000-0003-1162-687X")),
person("Reka","Toth", role = "aut", email = "r.toth@dkfz.de", comment = c(ORCID = "0000-0002-6096-1052")),
person("Rajbir","Batra", role = "ctb"), person("Clarissa","Feuerstein-Akgöz", role = "ctb"),
person("Joschka","Hey", role = "ctb"),
person("Maximilian","Schönung", role = "ctb"),
person("Pavlo","Lutsik", role = "ctb"))
Description: Bedgraph files generated by Bisulfite pipelines often come in various flavors. Critical downstream step requires summarization of these files into methylation/coverage matrices. This step of data aggregation is done by Methrix, including many other useful downstream functions.
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: false
Depends: R (>= 3.6), data.table (>= 1.12.4), SummarizedExperiment
Imports: rtracklayer, DelayedArray, HDF5Array, BSgenome, DelayedMatrixStats, parallel, methods, ggplot2, S4Vectors, matrixStats, graphics, stats, utils, GenomicRanges, IRanges
RoxygenNote: 7.1.1
Suggests:
knitr,
rmarkdown,
DSS,
bsseq,
plotly,
BSgenome.Mmusculus.UCSC.mm9,
MafDb.1Kgenomes.phase3.GRCh38,
MafDb.1Kgenomes.phase3.hs37d5,
BSgenome.Hsapiens.UCSC.hg19,
GenomicScores,
Biostrings,
RColorBrewer,
GenomeInfoDb,
testthat (>= 2.1.0)
VignetteBuilder: knitr
biocViews: DNAMethylation, Sequencing, Coverage
URL: https://github.com/CompEpigen/methrix
BugReports: https://github.com/CompEpigen/methrix/issues