08_AMP_validation.ipynb

{
 "cells": [
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# Part 2 - Validation on testes peptides"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Here is the procedure used to predicty activity, selectivity and hemolysis in all possible single, double, and triple mutants of protegrin-1. "
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 1,
   "metadata": {},
   "outputs": [],
   "source": [
    "import os\n",
    "import torch\n",
    "import numpy as np\n",
    "import pandas as pd\n",
    "import seaborn as sns\n",
    "import matplotlib.pyplot as plt\n",
    "from matplotlib_venn import venn3_unweighted\n",
    "\n",
    "\n",
    "import pickle\n",
    "import joblib\n",
    "\n",
    "import joblib\n",
    "from sklearn.decomposition import PCA\n",
    "from sklearn import metrics\n",
    "\n",
    "pd.set_option('display.max_columns', 100)\n",
    "\n",
    "%matplotlib inline"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 2,
   "metadata": {},
   "outputs": [],
   "source": [
    "# This function wil convert the undefined MIC values to 100.\n",
    "def convert_mic(mic_value):\n",
    "    if type(mic_value) == str and mic_value.startswith('>'):\n",
    "        mic_value = float(mic_value.replace('>', ''))\n",
    "        v = 100\n",
    "        return v\n",
    "    else:\n",
    "        return float(mic_value)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 19,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
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       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
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       "        vertical-align: top;\n",
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       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>ID</th>\n",
       "      <th>ID2</th>\n",
       "      <th>Sequence</th>\n",
       "      <th>RGGRLCYCRRRFCVCVGR</th>\n",
       "      <th>Select</th>\n",
       "      <th>Charge</th>\n",
       "      <th>group</th>\n",
       "      <th>MIC MH</th>\n",
       "      <th>%hemo</th>\n",
       "      <th>L10Select</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>PG1_3mut_1739000</td>\n",
       "      <td>bsPG-1.1</td>\n",
       "      <td>RGGRLQYCRRRFCVARGR</td>\n",
       "      <td>-----Q--------AR--</td>\n",
       "      <td>-0.82</td>\n",
       "      <td>6.742145</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>16</td>\n",
       "      <td>0.428850</td>\n",
       "      <td>0.836425</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>PG1_3mut_1218602</td>\n",
       "      <td>bsPG-1.2</td>\n",
       "      <td>RGGRLQYCRRRGCVTVGR</td>\n",
       "      <td>-----Q-----G--T---</td>\n",
       "      <td>-0.76</td>\n",
       "      <td>5.742155</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>4</td>\n",
       "      <td>0.341131</td>\n",
       "      <td>0.134981</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>PG1_3mut_1896424</td>\n",
       "      <td>bsPG-1.3</td>\n",
       "      <td>RGGRLAYCRRRDCTCVGR</td>\n",
       "      <td>-----A-----D-T----</td>\n",
       "      <td>-0.65</td>\n",
       "      <td>4.651497</td>\n",
       "      <td>CP</td>\n",
       "      <td>&gt;64</td>\n",
       "      <td>-0.165692</td>\n",
       "      <td>NaN</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>PG1_3mut_1275003</td>\n",
       "      <td>bsPG-1.4</td>\n",
       "      <td>RGGRLDYCRRRFCVTTGR</td>\n",
       "      <td>-----D--------TT--</td>\n",
       "      <td>-0.56</td>\n",
       "      <td>4.742406</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>64</td>\n",
       "      <td>0.165692</td>\n",
       "      <td>1.025482</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>PG1_3mut_257802</td>\n",
       "      <td>bsPG-1.5</td>\n",
       "      <td>RGGRLQACRRRFCVTVGR</td>\n",
       "      <td>-----QA-------T---</td>\n",
       "      <td>-0.44</td>\n",
       "      <td>5.744660</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>8</td>\n",
       "      <td>0.721248</td>\n",
       "      <td>0.761174</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5</th>\n",
       "      <td>PG1_3mut_1210489</td>\n",
       "      <td>bsPG-1.6</td>\n",
       "      <td>RGGRLRYCRRRFDVSVGR</td>\n",
       "      <td>-----R------D-S---</td>\n",
       "      <td>-0.43</td>\n",
       "      <td>5.833305</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>16</td>\n",
       "      <td>0.735867</td>\n",
       "      <td>1.070920</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6</th>\n",
       "      <td>PG1_3mut_1536372</td>\n",
       "      <td>bsPG-1.7</td>\n",
       "      <td>RGGRLCTARRRFCVRVGR</td>\n",
       "      <td>------TA------R---</td>\n",
       "      <td>-0.43</td>\n",
       "      <td>6.744650</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>2</td>\n",
       "      <td>0.906433</td>\n",
       "      <td>0.258366</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>7</th>\n",
       "      <td>PG1_3mut_1147726</td>\n",
       "      <td>bsPG-1.8</td>\n",
       "      <td>RGGRLTYCRRRFCTAVGR</td>\n",
       "      <td>-----T-------TA---</td>\n",
       "      <td>-0.40</td>\n",
       "      <td>5.742155</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>16</td>\n",
       "      <td>0.043860</td>\n",
       "      <td>-0.153815</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>8</th>\n",
       "      <td>PG1_3mut_1980555</td>\n",
       "      <td>bsPG-1.9</td>\n",
       "      <td>RGGRLTYCRRRDCVAVGR</td>\n",
       "      <td>-----T-----D--A---</td>\n",
       "      <td>-0.29</td>\n",
       "      <td>4.742406</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>32</td>\n",
       "      <td>0.116959</td>\n",
       "      <td>0.573184</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>9</th>\n",
       "      <td>PG1_3mut_1658870</td>\n",
       "      <td>bsPG-1.10</td>\n",
       "      <td>RGGRLAYCRRRFCVDTGR</td>\n",
       "      <td>-----A--------DT--</td>\n",
       "      <td>-0.28</td>\n",
       "      <td>4.742406</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>64</td>\n",
       "      <td>0.092593</td>\n",
       "      <td>0.772756</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>PG1_3mut_1618529</td>\n",
       "      <td>bsPG-1.11</td>\n",
       "      <td>RGGRLRYCRRRGTVCVGR</td>\n",
       "      <td>-----R-----GT-----</td>\n",
       "      <td>-0.28</td>\n",
       "      <td>6.742145</td>\n",
       "      <td>CP</td>\n",
       "      <td>&gt;64</td>\n",
       "      <td>0.268031</td>\n",
       "      <td>NaN</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>11</th>\n",
       "      <td>PG1_3mut_720432</td>\n",
       "      <td>bsPG-1.12</td>\n",
       "      <td>RGGRLQYCRRRFCARVGR</td>\n",
       "      <td>-----Q-------AR---</td>\n",
       "      <td>-0.27</td>\n",
       "      <td>6.742145</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>16</td>\n",
       "      <td>0.141326</td>\n",
       "      <td>0.354341</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12</th>\n",
       "      <td>PG1_3mut_1247939</td>\n",
       "      <td>bsPG-1.13</td>\n",
       "      <td>RGGRLCYCRRRNCVTTGR</td>\n",
       "      <td>-----------N--TT--</td>\n",
       "      <td>-0.25</td>\n",
       "      <td>5.651245</td>\n",
       "      <td>-0.25-0</td>\n",
       "      <td>&gt;64</td>\n",
       "      <td>-0.058480</td>\n",
       "      <td>NaN</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13</th>\n",
       "      <td>PG1_3mut_1926344</td>\n",
       "      <td>bsPG-1.14</td>\n",
       "      <td>RGGRLCTARRRFCVHVGR</td>\n",
       "      <td>------TA------H---</td>\n",
       "      <td>-0.22</td>\n",
       "      <td>5.835569</td>\n",
       "      <td>-0.25-0</td>\n",
       "      <td>16</td>\n",
       "      <td>0.638402</td>\n",
       "      <td>1.009214</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14</th>\n",
       "      <td>PG1_3mut_70973</td>\n",
       "      <td>bsPG-1.15</td>\n",
       "      <td>RGGRLCDCRRRFCNMVGR</td>\n",
       "      <td>------D------NM---</td>\n",
       "      <td>-0.15</td>\n",
       "      <td>4.654002</td>\n",
       "      <td>-0.25-0</td>\n",
       "      <td>&gt;64</td>\n",
       "      <td>-0.097466</td>\n",
       "      <td>NaN</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15</th>\n",
       "      <td>PG1_3mut_969074</td>\n",
       "      <td>bsPG-1.16</td>\n",
       "      <td>RGGRLQYCRRRFDTCVGR</td>\n",
       "      <td>-----Q------DT----</td>\n",
       "      <td>-0.14</td>\n",
       "      <td>4.742406</td>\n",
       "      <td>-0.25-0</td>\n",
       "      <td>&gt;64</td>\n",
       "      <td>0.034113</td>\n",
       "      <td>NaN</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16</th>\n",
       "      <td>PG1_3mut_624778</td>\n",
       "      <td>bsPG-1.17</td>\n",
       "      <td>RGGRLCTCRRRFCASVGR</td>\n",
       "      <td>------T------AS---</td>\n",
       "      <td>-0.14</td>\n",
       "      <td>5.653751</td>\n",
       "      <td>-0.25-0</td>\n",
       "      <td>32</td>\n",
       "      <td>0.487329</td>\n",
       "      <td>1.192973</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17</th>\n",
       "      <td>PG1_3mut_1114717</td>\n",
       "      <td>bsPG-1.18</td>\n",
       "      <td>RGGRLRYCRRRFRVSVGR</td>\n",
       "      <td>-----R------R-S---</td>\n",
       "      <td>-0.13</td>\n",
       "      <td>7.833044</td>\n",
       "      <td>-0.25-0</td>\n",
       "      <td>16</td>\n",
       "      <td>1.525341</td>\n",
       "      <td>1.387487</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>18</th>\n",
       "      <td>PG1_3mut_902003</td>\n",
       "      <td>bsPG-1.19</td>\n",
       "      <td>RGGRLEYCRRRFCVNTGR</td>\n",
       "      <td>-----E--------NT--</td>\n",
       "      <td>-0.13</td>\n",
       "      <td>4.742552</td>\n",
       "      <td>-0.25-0</td>\n",
       "      <td>&gt;64</td>\n",
       "      <td>1.281676</td>\n",
       "      <td>NaN</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19</th>\n",
       "      <td>PG1_3mut_484549</td>\n",
       "      <td>bsPG-1.20</td>\n",
       "      <td>RGGRLTYCRRRFCADVGR</td>\n",
       "      <td>-----T-------AD---</td>\n",
       "      <td>-0.10</td>\n",
       "      <td>4.742406</td>\n",
       "      <td>-0.25-0</td>\n",
       "      <td>64</td>\n",
       "      <td>0.248538</td>\n",
       "      <td>1.201573</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>20</th>\n",
       "      <td>PG1_3mut_789807</td>\n",
       "      <td>bsPG-1.21</td>\n",
       "      <td>RGGRLCYRRRRTAVCVGR</td>\n",
       "      <td>-------R---TA-----</td>\n",
       "      <td>-0.10</td>\n",
       "      <td>6.742145</td>\n",
       "      <td>CP</td>\n",
       "      <td>8</td>\n",
       "      <td>0.404483</td>\n",
       "      <td>0.509991</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21</th>\n",
       "      <td>PG1_3mut_1838343</td>\n",
       "      <td>bsPG-1.22</td>\n",
       "      <td>RGGRLCYCRRRFCTPVTR</td>\n",
       "      <td>-------------TP-T-</td>\n",
       "      <td>-0.03</td>\n",
       "      <td>5.651245</td>\n",
       "      <td>-0.25-0</td>\n",
       "      <td>64</td>\n",
       "      <td>0.389864</td>\n",
       "      <td>1.397093</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>22</th>\n",
       "      <td>PG1_3mut_945905</td>\n",
       "      <td>bsPG-1.23</td>\n",
       "      <td>RTGRLCYCRRRDCTCVGR</td>\n",
       "      <td>-T---------D-T----</td>\n",
       "      <td>-0.02</td>\n",
       "      <td>4.560587</td>\n",
       "      <td>CP</td>\n",
       "      <td>32</td>\n",
       "      <td>0.053606</td>\n",
       "      <td>0.234365</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23</th>\n",
       "      <td>PG1_3mut_26231</td>\n",
       "      <td>bsPG-1.24</td>\n",
       "      <td>RGGRLHYRRRRFCVRVGR</td>\n",
       "      <td>-----H-R------R---</td>\n",
       "      <td>-0.01</td>\n",
       "      <td>7.923953</td>\n",
       "      <td>-0.25-0</td>\n",
       "      <td>8</td>\n",
       "      <td>9.722222</td>\n",
       "      <td>1.890856</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24</th>\n",
       "      <td>PG1_3mut_485919</td>\n",
       "      <td>bsPG-1.25</td>\n",
       "      <td>RGGRPCYCRRRFCGTVGR</td>\n",
       "      <td>----P--------GT---</td>\n",
       "      <td>0.03</td>\n",
       "      <td>5.651245</td>\n",
       "      <td>0-0.5</td>\n",
       "      <td>&gt;64</td>\n",
       "      <td>-0.009747</td>\n",
       "      <td>NaN</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>25</th>\n",
       "      <td>PG1_3mut_437553</td>\n",
       "      <td>bsPG-1.26</td>\n",
       "      <td>RGGRLCDCRRRTCRCVGR</td>\n",
       "      <td>------D----T-R----</td>\n",
       "      <td>0.04</td>\n",
       "      <td>5.563083</td>\n",
       "      <td>CP</td>\n",
       "      <td>&gt;64</td>\n",
       "      <td>0.194932</td>\n",
       "      <td>NaN</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26</th>\n",
       "      <td>PG1_3mut_840730</td>\n",
       "      <td>bsPG-1.27</td>\n",
       "      <td>RGGRDIYCRRRFCVTVGR</td>\n",
       "      <td>----DI--------T---</td>\n",
       "      <td>0.10</td>\n",
       "      <td>4.742406</td>\n",
       "      <td>0-0.5</td>\n",
       "      <td>8</td>\n",
       "      <td>0.662768</td>\n",
       "      <td>0.724452</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>27</th>\n",
       "      <td>PG1_3mut_1102178</td>\n",
       "      <td>bsPG-1.28</td>\n",
       "      <td>RGGRLCYCRRRTCVDTGR</td>\n",
       "      <td>-----------T--DT--</td>\n",
       "      <td>0.17</td>\n",
       "      <td>4.651497</td>\n",
       "      <td>0-0.5</td>\n",
       "      <td>32</td>\n",
       "      <td>0.160819</td>\n",
       "      <td>0.711487</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>28</th>\n",
       "      <td>PG1_3mut_939583</td>\n",
       "      <td>bsPG-1.29</td>\n",
       "      <td>RGGRLCYSRRRFCKTVGR</td>\n",
       "      <td>-------S-----KT---</td>\n",
       "      <td>0.33</td>\n",
       "      <td>6.741654</td>\n",
       "      <td>0-0.5</td>\n",
       "      <td>64</td>\n",
       "      <td>0.560429</td>\n",
       "      <td>1.554700</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>29</th>\n",
       "      <td>PG1_3mut_439660</td>\n",
       "      <td>bsPG-1.30</td>\n",
       "      <td>RGGRLAYCRRRFCVAVAR</td>\n",
       "      <td>-----A--------A-A-</td>\n",
       "      <td>0.36</td>\n",
       "      <td>5.742155</td>\n",
       "      <td>0-0.5</td>\n",
       "      <td>2</td>\n",
       "      <td>1.076998</td>\n",
       "      <td>0.333245</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>30</th>\n",
       "      <td>PG1_3mut_341044</td>\n",
       "      <td>bsPG-1.31</td>\n",
       "      <td>RGGRLCYGRRRFCVNQGR</td>\n",
       "      <td>-------G------NQ--</td>\n",
       "      <td>0.37</td>\n",
       "      <td>5.742155</td>\n",
       "      <td>0-0.5</td>\n",
       "      <td>32</td>\n",
       "      <td>2.061404</td>\n",
       "      <td>1.819313</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>31</th>\n",
       "      <td>PG1_3mut_1166571</td>\n",
       "      <td>bsPG-1.32</td>\n",
       "      <td>RGGRSCHCRRRFCVIVGR</td>\n",
       "      <td>----S-H-------I---</td>\n",
       "      <td>0.37</td>\n",
       "      <td>5.744660</td>\n",
       "      <td>0-0.5</td>\n",
       "      <td>4</td>\n",
       "      <td>15.696881</td>\n",
       "      <td>1.797873</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>32</th>\n",
       "      <td>PG1_3mut_1080117</td>\n",
       "      <td>bsPG-1.33</td>\n",
       "      <td>RGRRACYCRRRFCVHVGR</td>\n",
       "      <td>--R-A---------H---</td>\n",
       "      <td>0.38</td>\n",
       "      <td>6.742145</td>\n",
       "      <td>0-0.5</td>\n",
       "      <td>4</td>\n",
       "      <td>3.664717</td>\n",
       "      <td>1.166100</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>33</th>\n",
       "      <td>PG1_3mut_261082</td>\n",
       "      <td>bsPG-1.34</td>\n",
       "      <td>RGGRLSYCRRRFCVAGGR</td>\n",
       "      <td>-----S--------AG--</td>\n",
       "      <td>0.40</td>\n",
       "      <td>5.742155</td>\n",
       "      <td>0-0.5</td>\n",
       "      <td>16</td>\n",
       "      <td>0.321637</td>\n",
       "      <td>0.711487</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>34</th>\n",
       "      <td>PG1_3mut_881885</td>\n",
       "      <td>bsPG-1.35</td>\n",
       "      <td>RGQRLCYCRRRFNVCTGR</td>\n",
       "      <td>--Q---------N--T--</td>\n",
       "      <td>0.41</td>\n",
       "      <td>5.651245</td>\n",
       "      <td>CP</td>\n",
       "      <td>32</td>\n",
       "      <td>0.399610</td>\n",
       "      <td>1.106786</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>35</th>\n",
       "      <td>PG1_3mut_702701</td>\n",
       "      <td>bsPG-1.36</td>\n",
       "      <td>RGGRLCYCRRRFCAVNGR</td>\n",
       "      <td>-------------AVN--</td>\n",
       "      <td>0.45</td>\n",
       "      <td>5.651245</td>\n",
       "      <td>0-0.5</td>\n",
       "      <td>64</td>\n",
       "      <td>0.116959</td>\n",
       "      <td>0.874214</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "                  ID        ID2            Sequence  RGGRLCYCRRRFCVCVGR  \\\n",
       "0   PG1_3mut_1739000   bsPG-1.1  RGGRLQYCRRRFCVARGR  -----Q--------AR--   \n",
       "1   PG1_3mut_1218602   bsPG-1.2  RGGRLQYCRRRGCVTVGR  -----Q-----G--T---   \n",
       "2   PG1_3mut_1896424   bsPG-1.3  RGGRLAYCRRRDCTCVGR  -----A-----D-T----   \n",
       "3   PG1_3mut_1275003   bsPG-1.4  RGGRLDYCRRRFCVTTGR  -----D--------TT--   \n",
       "4    PG1_3mut_257802   bsPG-1.5  RGGRLQACRRRFCVTVGR  -----QA-------T---   \n",
       "5   PG1_3mut_1210489   bsPG-1.6  RGGRLRYCRRRFDVSVGR  -----R------D-S---   \n",
       "6   PG1_3mut_1536372   bsPG-1.7  RGGRLCTARRRFCVRVGR  ------TA------R---   \n",
       "7   PG1_3mut_1147726   bsPG-1.8  RGGRLTYCRRRFCTAVGR  -----T-------TA---   \n",
       "8   PG1_3mut_1980555   bsPG-1.9  RGGRLTYCRRRDCVAVGR  -----T-----D--A---   \n",
       "9   PG1_3mut_1658870  bsPG-1.10  RGGRLAYCRRRFCVDTGR  -----A--------DT--   \n",
       "10  PG1_3mut_1618529  bsPG-1.11  RGGRLRYCRRRGTVCVGR  -----R-----GT-----   \n",
       "11   PG1_3mut_720432  bsPG-1.12  RGGRLQYCRRRFCARVGR  -----Q-------AR---   \n",
       "12  PG1_3mut_1247939  bsPG-1.13  RGGRLCYCRRRNCVTTGR  -----------N--TT--   \n",
       "13  PG1_3mut_1926344  bsPG-1.14  RGGRLCTARRRFCVHVGR  ------TA------H---   \n",
       "14    PG1_3mut_70973  bsPG-1.15  RGGRLCDCRRRFCNMVGR  ------D------NM---   \n",
       "15   PG1_3mut_969074  bsPG-1.16  RGGRLQYCRRRFDTCVGR  -----Q------DT----   \n",
       "16   PG1_3mut_624778  bsPG-1.17  RGGRLCTCRRRFCASVGR  ------T------AS---   \n",
       "17  PG1_3mut_1114717  bsPG-1.18  RGGRLRYCRRRFRVSVGR  -----R------R-S---   \n",
       "18   PG1_3mut_902003  bsPG-1.19  RGGRLEYCRRRFCVNTGR  -----E--------NT--   \n",
       "19   PG1_3mut_484549  bsPG-1.20  RGGRLTYCRRRFCADVGR  -----T-------AD---   \n",
       "20   PG1_3mut_789807  bsPG-1.21  RGGRLCYRRRRTAVCVGR  -------R---TA-----   \n",
       "21  PG1_3mut_1838343  bsPG-1.22  RGGRLCYCRRRFCTPVTR  -------------TP-T-   \n",
       "22   PG1_3mut_945905  bsPG-1.23  RTGRLCYCRRRDCTCVGR  -T---------D-T----   \n",
       "23    PG1_3mut_26231  bsPG-1.24  RGGRLHYRRRRFCVRVGR  -----H-R------R---   \n",
       "24   PG1_3mut_485919  bsPG-1.25  RGGRPCYCRRRFCGTVGR  ----P--------GT---   \n",
       "25   PG1_3mut_437553  bsPG-1.26  RGGRLCDCRRRTCRCVGR  ------D----T-R----   \n",
       "26   PG1_3mut_840730  bsPG-1.27  RGGRDIYCRRRFCVTVGR  ----DI--------T---   \n",
       "27  PG1_3mut_1102178  bsPG-1.28  RGGRLCYCRRRTCVDTGR  -----------T--DT--   \n",
       "28   PG1_3mut_939583  bsPG-1.29  RGGRLCYSRRRFCKTVGR  -------S-----KT---   \n",
       "29   PG1_3mut_439660  bsPG-1.30  RGGRLAYCRRRFCVAVAR  -----A--------A-A-   \n",
       "30   PG1_3mut_341044  bsPG-1.31  RGGRLCYGRRRFCVNQGR  -------G------NQ--   \n",
       "31  PG1_3mut_1166571  bsPG-1.32  RGGRSCHCRRRFCVIVGR  ----S-H-------I---   \n",
       "32  PG1_3mut_1080117  bsPG-1.33  RGRRACYCRRRFCVHVGR  --R-A---------H---   \n",
       "33   PG1_3mut_261082  bsPG-1.34  RGGRLSYCRRRFCVAGGR  -----S--------AG--   \n",
       "34   PG1_3mut_881885  bsPG-1.35  RGQRLCYCRRRFNVCTGR  --Q---------N--T--   \n",
       "35   PG1_3mut_702701  bsPG-1.36  RGGRLCYCRRRFCAVNGR  -------------AVN--   \n",
       "\n",
       "    Select    Charge    group MIC MH      %hemo  L10Select  \n",
       "0    -0.82  6.742145   <-0.25     16   0.428850   0.836425  \n",
       "1    -0.76  5.742155   <-0.25      4   0.341131   0.134981  \n",
       "2    -0.65  4.651497       CP    >64  -0.165692        NaN  \n",
       "3    -0.56  4.742406   <-0.25     64   0.165692   1.025482  \n",
       "4    -0.44  5.744660   <-0.25      8   0.721248   0.761174  \n",
       "5    -0.43  5.833305   <-0.25     16   0.735867   1.070920  \n",
       "6    -0.43  6.744650   <-0.25      2   0.906433   0.258366  \n",
       "7    -0.40  5.742155   <-0.25     16   0.043860  -0.153815  \n",
       "8    -0.29  4.742406   <-0.25     32   0.116959   0.573184  \n",
       "9    -0.28  4.742406   <-0.25     64   0.092593   0.772756  \n",
       "10   -0.28  6.742145       CP    >64   0.268031        NaN  \n",
       "11   -0.27  6.742145   <-0.25     16   0.141326   0.354341  \n",
       "12   -0.25  5.651245  -0.25-0    >64  -0.058480        NaN  \n",
       "13   -0.22  5.835569  -0.25-0     16   0.638402   1.009214  \n",
       "14   -0.15  4.654002  -0.25-0    >64  -0.097466        NaN  \n",
       "15   -0.14  4.742406  -0.25-0    >64   0.034113        NaN  \n",
       "16   -0.14  5.653751  -0.25-0     32   0.487329   1.192973  \n",
       "17   -0.13  7.833044  -0.25-0     16   1.525341   1.387487  \n",
       "18   -0.13  4.742552  -0.25-0    >64   1.281676        NaN  \n",
       "19   -0.10  4.742406  -0.25-0     64   0.248538   1.201573  \n",
       "20   -0.10  6.742145       CP      8   0.404483   0.509991  \n",
       "21   -0.03  5.651245  -0.25-0     64   0.389864   1.397093  \n",
       "22   -0.02  4.560587       CP     32   0.053606   0.234365  \n",
       "23   -0.01  7.923953  -0.25-0      8   9.722222   1.890856  \n",
       "24    0.03  5.651245    0-0.5    >64  -0.009747        NaN  \n",
       "25    0.04  5.563083       CP    >64   0.194932        NaN  \n",
       "26    0.10  4.742406    0-0.5      8   0.662768   0.724452  \n",
       "27    0.17  4.651497    0-0.5     32   0.160819   0.711487  \n",
       "28    0.33  6.741654    0-0.5     64   0.560429   1.554700  \n",
       "29    0.36  5.742155    0-0.5      2   1.076998   0.333245  \n",
       "30    0.37  5.742155    0-0.5     32   2.061404   1.819313  \n",
       "31    0.37  5.744660    0-0.5      4  15.696881   1.797873  \n",
       "32    0.38  6.742145    0-0.5      4   3.664717   1.166100  \n",
       "33    0.40  5.742155    0-0.5     16   0.321637   0.711487  \n",
       "34    0.41  5.651245       CP     32   0.399610   1.106786  \n",
       "35    0.45  5.651245    0-0.5     64   0.116959   0.874214  "
      ]
     },
     "execution_count": 19,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "# load meta_data with mutations on PG1\n",
    "meta_data = pd.read_excel('data/pg1_muts_validation_set_v01.2.xlsx')\n",
    "meta_data"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Load embeddings"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 20,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>0</th>\n",
       "      <th>1</th>\n",
       "      <th>2</th>\n",
       "      <th>3</th>\n",
       "      <th>4</th>\n",
       "      <th>5</th>\n",
       "      <th>6</th>\n",
       "      <th>7</th>\n",
       "      <th>8</th>\n",
       "      <th>9</th>\n",
       "      <th>10</th>\n",
       "      <th>11</th>\n",
       "      <th>12</th>\n",
       "      <th>13</th>\n",
       "      <th>14</th>\n",
       "      <th>15</th>\n",
       "      <th>16</th>\n",
       "      <th>17</th>\n",
       "      <th>18</th>\n",
       "      <th>19</th>\n",
       "      <th>20</th>\n",
       "      <th>21</th>\n",
       "      <th>22</th>\n",
       "      <th>23</th>\n",
       "      <th>24</th>\n",
       "      <th>25</th>\n",
       "      <th>26</th>\n",
       "      <th>27</th>\n",
       "      <th>28</th>\n",
       "      <th>29</th>\n",
       "      <th>30</th>\n",
       "      <th>31</th>\n",
       "      <th>32</th>\n",
       "      <th>33</th>\n",
       "      <th>34</th>\n",
       "      <th>35</th>\n",
       "      <th>36</th>\n",
       "      <th>37</th>\n",
       "      <th>38</th>\n",
       "      <th>39</th>\n",
       "      <th>40</th>\n",
       "      <th>41</th>\n",
       "      <th>42</th>\n",
       "      <th>43</th>\n",
       "      <th>44</th>\n",
       "      <th>45</th>\n",
       "      <th>46</th>\n",
       "      <th>47</th>\n",
       "      <th>48</th>\n",
       "      <th>49</th>\n",
       "      <th>...</th>\n",
       "      <th>5070</th>\n",
       "      <th>5071</th>\n",
       "      <th>5072</th>\n",
       "      <th>5073</th>\n",
       "      <th>5074</th>\n",
       "      <th>5075</th>\n",
       "      <th>5076</th>\n",
       "      <th>5077</th>\n",
       "      <th>5078</th>\n",
       "      <th>5079</th>\n",
       "      <th>5080</th>\n",
       "      <th>5081</th>\n",
       "      <th>5082</th>\n",
       "      <th>5083</th>\n",
       "      <th>5084</th>\n",
       "      <th>5085</th>\n",
       "      <th>5086</th>\n",
       "      <th>5087</th>\n",
       "      <th>5088</th>\n",
       "      <th>5089</th>\n",
       "      <th>5090</th>\n",
       "      <th>5091</th>\n",
       "      <th>5092</th>\n",
       "      <th>5093</th>\n",
       "      <th>5094</th>\n",
       "      <th>5095</th>\n",
       "      <th>5096</th>\n",
       "      <th>5097</th>\n",
       "      <th>5098</th>\n",
       "      <th>5099</th>\n",
       "      <th>5100</th>\n",
       "      <th>5101</th>\n",
       "      <th>5102</th>\n",
       "      <th>5103</th>\n",
       "      <th>5104</th>\n",
       "      <th>5105</th>\n",
       "      <th>5106</th>\n",
       "      <th>5107</th>\n",
       "      <th>5108</th>\n",
       "      <th>5109</th>\n",
       "      <th>5110</th>\n",
       "      <th>5111</th>\n",
       "      <th>5112</th>\n",
       "      <th>5113</th>\n",
       "      <th>5114</th>\n",
       "      <th>5115</th>\n",
       "      <th>5116</th>\n",
       "      <th>5117</th>\n",
       "      <th>5118</th>\n",
       "      <th>5119</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>0.109975</td>\n",
       "      <td>-0.134590</td>\n",
       "      <td>-0.111443</td>\n",
       "      <td>0.218644</td>\n",
       "      <td>-0.237748</td>\n",
       "      <td>0.131493</td>\n",
       "      <td>-0.119502</td>\n",
       "      <td>0.234007</td>\n",
       "      <td>-0.042554</td>\n",
       "      <td>0.338132</td>\n",
       "      <td>-0.181911</td>\n",
       "      <td>-0.070123</td>\n",
       "      <td>0.285914</td>\n",
       "      <td>0.132456</td>\n",
       "      <td>0.145206</td>\n",
       "      <td>-0.119641</td>\n",
       "      <td>0.016052</td>\n",
       "      <td>-0.160409</td>\n",
       "      <td>0.175323</td>\n",
       "      <td>0.006981</td>\n",
       "      <td>0.031700</td>\n",
       "      <td>0.035921</td>\n",
       "      <td>-0.388611</td>\n",
       "      <td>0.106619</td>\n",
       "      <td>-0.263324</td>\n",
       "      <td>0.010144</td>\n",
       "      <td>0.089600</td>\n",
       "      <td>-0.232413</td>\n",
       "      <td>0.044148</td>\n",
       "      <td>0.205849</td>\n",
       "      <td>-0.088589</td>\n",
       "      <td>-0.051135</td>\n",
       "      <td>-0.249299</td>\n",
       "      <td>-0.100425</td>\n",
       "      <td>-0.034155</td>\n",
       "      <td>-0.042539</td>\n",
       "      <td>0.145001</td>\n",
       "      <td>-0.053556</td>\n",
       "      <td>0.325825</td>\n",
       "      <td>0.009630</td>\n",
       "      <td>0.188548</td>\n",
       "      <td>-0.276242</td>\n",
       "      <td>0.057267</td>\n",
       "      <td>0.159372</td>\n",
       "      <td>-0.074977</td>\n",
       "      <td>0.383486</td>\n",
       "      <td>-0.059249</td>\n",
       "      <td>0.067180</td>\n",
       "      <td>-0.192458</td>\n",
       "      <td>-0.160447</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.287571</td>\n",
       "      <td>-0.199986</td>\n",
       "      <td>0.265588</td>\n",
       "      <td>-0.087591</td>\n",
       "      <td>-0.035537</td>\n",
       "      <td>0.052414</td>\n",
       "      <td>-0.032724</td>\n",
       "      <td>0.074804</td>\n",
       "      <td>0.253470</td>\n",
       "      <td>0.188196</td>\n",
       "      <td>0.000840</td>\n",
       "      <td>-0.048806</td>\n",
       "      <td>0.006446</td>\n",
       "      <td>0.150435</td>\n",
       "      <td>0.038589</td>\n",
       "      <td>0.085381</td>\n",
       "      <td>-0.230726</td>\n",
       "      <td>0.268536</td>\n",
       "      <td>-0.116890</td>\n",
       "      <td>-0.014526</td>\n",
       "      <td>-0.264989</td>\n",
       "      <td>-0.072022</td>\n",
       "      <td>-0.083098</td>\n",
       "      <td>-0.169087</td>\n",
       "      <td>0.285792</td>\n",
       "      <td>0.045038</td>\n",
       "      <td>0.190472</td>\n",
       "      <td>-0.006061</td>\n",
       "      <td>0.086329</td>\n",
       "      <td>-0.000662</td>\n",
       "      <td>0.091908</td>\n",
       "      <td>0.035746</td>\n",
       "      <td>-0.148846</td>\n",
       "      <td>-0.118648</td>\n",
       "      <td>-0.209491</td>\n",
       "      <td>-0.021450</td>\n",
       "      <td>-0.027162</td>\n",
       "      <td>-0.213849</td>\n",
       "      <td>-0.050013</td>\n",
       "      <td>0.006487</td>\n",
       "      <td>-0.136047</td>\n",
       "      <td>-0.087660</td>\n",
       "      <td>0.107472</td>\n",
       "      <td>-0.270478</td>\n",
       "      <td>0.122341</td>\n",
       "      <td>-0.089307</td>\n",
       "      <td>0.137297</td>\n",
       "      <td>0.075365</td>\n",
       "      <td>-0.198461</td>\n",
       "      <td>-0.035045</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>0.129701</td>\n",
       "      <td>-0.184889</td>\n",
       "      <td>-0.115536</td>\n",
       "      <td>0.161651</td>\n",
       "      <td>-0.224050</td>\n",
       "      <td>0.112427</td>\n",
       "      <td>-0.157890</td>\n",
       "      <td>0.269912</td>\n",
       "      <td>-0.049523</td>\n",
       "      <td>0.307800</td>\n",
       "      <td>-0.149578</td>\n",
       "      <td>-0.081749</td>\n",
       "      <td>0.265789</td>\n",
       "      <td>0.177847</td>\n",
       "      <td>0.169391</td>\n",
       "      <td>-0.094384</td>\n",
       "      <td>0.128813</td>\n",
       "      <td>-0.176698</td>\n",
       "      <td>0.105074</td>\n",
       "      <td>0.014042</td>\n",
       "      <td>0.026007</td>\n",
       "      <td>0.069966</td>\n",
       "      <td>-0.333289</td>\n",
       "      <td>0.142775</td>\n",
       "      <td>-0.248938</td>\n",
       "      <td>-0.029828</td>\n",
       "      <td>0.020388</td>\n",
       "      <td>-0.144963</td>\n",
       "      <td>0.050747</td>\n",
       "      <td>0.161994</td>\n",
       "      <td>-0.136832</td>\n",
       "      <td>-0.064507</td>\n",
       "      <td>-0.254568</td>\n",
       "      <td>-0.029669</td>\n",
       "      <td>-0.057159</td>\n",
       "      <td>0.031107</td>\n",
       "      <td>0.171488</td>\n",
       "      <td>-0.025439</td>\n",
       "      <td>0.370129</td>\n",
       "      <td>-0.041123</td>\n",
       "      <td>0.135727</td>\n",
       "      <td>-0.279007</td>\n",
       "      <td>0.066811</td>\n",
       "      <td>0.166149</td>\n",
       "      <td>-0.087821</td>\n",
       "      <td>0.364228</td>\n",
       "      <td>-0.020949</td>\n",
       "      <td>0.117404</td>\n",
       "      <td>-0.246447</td>\n",
       "      <td>-0.102719</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.252198</td>\n",
       "      <td>-0.117499</td>\n",
       "      <td>0.283669</td>\n",
       "      <td>-0.081878</td>\n",
       "      <td>-0.082878</td>\n",
       "      <td>0.056859</td>\n",
       "      <td>-0.002050</td>\n",
       "      <td>0.037367</td>\n",
       "      <td>0.262278</td>\n",
       "      <td>0.109654</td>\n",
       "      <td>0.026107</td>\n",
       "      <td>0.013662</td>\n",
       "      <td>0.029625</td>\n",
       "      <td>0.179096</td>\n",
       "      <td>0.087634</td>\n",
       "      <td>0.068997</td>\n",
       "      <td>-0.194529</td>\n",
       "      <td>0.256631</td>\n",
       "      <td>-0.086368</td>\n",
       "      <td>0.013377</td>\n",
       "      <td>-0.315640</td>\n",
       "      <td>-0.012413</td>\n",
       "      <td>-0.098380</td>\n",
       "      <td>-0.130370</td>\n",
       "      <td>0.274497</td>\n",
       "      <td>0.049318</td>\n",
       "      <td>0.221853</td>\n",
       "      <td>-0.059104</td>\n",
       "      <td>0.077843</td>\n",
       "      <td>-0.038710</td>\n",
       "      <td>0.128514</td>\n",
       "      <td>0.042598</td>\n",
       "      <td>-0.170303</td>\n",
       "      <td>-0.052412</td>\n",
       "      <td>-0.178424</td>\n",
       "      <td>-0.050331</td>\n",
       "      <td>-0.044874</td>\n",
       "      <td>-0.277650</td>\n",
       "      <td>0.018790</td>\n",
       "      <td>-0.008888</td>\n",
       "      <td>-0.106790</td>\n",
       "      <td>-0.129787</td>\n",
       "      <td>0.076798</td>\n",
       "      <td>-0.208119</td>\n",
       "      <td>0.098149</td>\n",
       "      <td>-0.133004</td>\n",
       "      <td>0.089372</td>\n",
       "      <td>0.093026</td>\n",
       "      <td>-0.170869</td>\n",
       "      <td>-0.013929</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>0.099468</td>\n",
       "      <td>-0.114953</td>\n",
       "      <td>-0.117187</td>\n",
       "      <td>0.183187</td>\n",
       "      <td>-0.209792</td>\n",
       "      <td>0.091260</td>\n",
       "      <td>-0.130392</td>\n",
       "      <td>0.256235</td>\n",
       "      <td>-0.053187</td>\n",
       "      <td>0.229403</td>\n",
       "      <td>-0.153716</td>\n",
       "      <td>-0.110329</td>\n",
       "      <td>0.224579</td>\n",
       "      <td>0.217258</td>\n",
       "      <td>0.185253</td>\n",
       "      <td>-0.137833</td>\n",
       "      <td>0.123428</td>\n",
       "      <td>-0.071266</td>\n",
       "      <td>0.113991</td>\n",
       "      <td>-0.005573</td>\n",
       "      <td>0.083241</td>\n",
       "      <td>0.095849</td>\n",
       "      <td>-0.291120</td>\n",
       "      <td>0.084410</td>\n",
       "      <td>-0.293609</td>\n",
       "      <td>-0.046842</td>\n",
       "      <td>0.064312</td>\n",
       "      <td>-0.096830</td>\n",
       "      <td>0.032436</td>\n",
       "      <td>0.084759</td>\n",
       "      <td>-0.103322</td>\n",
       "      <td>-0.039152</td>\n",
       "      <td>-0.284039</td>\n",
       "      <td>-0.067096</td>\n",
       "      <td>-0.115826</td>\n",
       "      <td>0.051603</td>\n",
       "      <td>0.165042</td>\n",
       "      <td>-0.094658</td>\n",
       "      <td>0.376194</td>\n",
       "      <td>-0.128548</td>\n",
       "      <td>0.181254</td>\n",
       "      <td>-0.249639</td>\n",
       "      <td>0.065785</td>\n",
       "      <td>0.160171</td>\n",
       "      <td>-0.091013</td>\n",
       "      <td>0.350580</td>\n",
       "      <td>0.005549</td>\n",
       "      <td>0.078152</td>\n",
       "      <td>-0.205696</td>\n",
       "      <td>-0.069624</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.265148</td>\n",
       "      <td>-0.125474</td>\n",
       "      <td>0.232081</td>\n",
       "      <td>-0.136144</td>\n",
       "      <td>-0.026184</td>\n",
       "      <td>0.075733</td>\n",
       "      <td>0.041864</td>\n",
       "      <td>0.058491</td>\n",
       "      <td>0.310277</td>\n",
       "      <td>0.156786</td>\n",
       "      <td>-0.067325</td>\n",
       "      <td>0.029883</td>\n",
       "      <td>0.027132</td>\n",
       "      <td>0.108766</td>\n",
       "      <td>0.068593</td>\n",
       "      <td>-0.053529</td>\n",
       "      <td>-0.139792</td>\n",
       "      <td>0.200807</td>\n",
       "      <td>-0.150195</td>\n",
       "      <td>0.036576</td>\n",
       "      <td>-0.200391</td>\n",
       "      <td>-0.061608</td>\n",
       "      <td>-0.052911</td>\n",
       "      <td>-0.173216</td>\n",
       "      <td>0.241643</td>\n",
       "      <td>0.071768</td>\n",
       "      <td>0.181315</td>\n",
       "      <td>-0.034740</td>\n",
       "      <td>0.006019</td>\n",
       "      <td>-0.071225</td>\n",
       "      <td>0.139590</td>\n",
       "      <td>0.150875</td>\n",
       "      <td>-0.073768</td>\n",
       "      <td>-0.083165</td>\n",
       "      <td>-0.124568</td>\n",
       "      <td>-0.063161</td>\n",
       "      <td>-0.023962</td>\n",
       "      <td>-0.257893</td>\n",
       "      <td>0.000161</td>\n",
       "      <td>0.006935</td>\n",
       "      <td>-0.195330</td>\n",
       "      <td>-0.116773</td>\n",
       "      <td>0.137988</td>\n",
       "      <td>-0.164647</td>\n",
       "      <td>0.119364</td>\n",
       "      <td>-0.178338</td>\n",
       "      <td>0.031593</td>\n",
       "      <td>0.029154</td>\n",
       "      <td>-0.215111</td>\n",
       "      <td>-0.017543</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>0.156776</td>\n",
       "      <td>-0.105166</td>\n",
       "      <td>-0.063266</td>\n",
       "      <td>0.204592</td>\n",
       "      <td>-0.202521</td>\n",
       "      <td>0.076685</td>\n",
       "      <td>-0.140390</td>\n",
       "      <td>0.251750</td>\n",
       "      <td>-0.082083</td>\n",
       "      <td>0.299491</td>\n",
       "      <td>-0.138542</td>\n",
       "      <td>-0.093754</td>\n",
       "      <td>0.238516</td>\n",
       "      <td>0.210513</td>\n",
       "      <td>0.224224</td>\n",
       "      <td>-0.099772</td>\n",
       "      <td>0.084619</td>\n",
       "      <td>-0.138276</td>\n",
       "      <td>0.065005</td>\n",
       "      <td>0.034831</td>\n",
       "      <td>0.028210</td>\n",
       "      <td>0.085703</td>\n",
       "      <td>-0.210246</td>\n",
       "      <td>0.129641</td>\n",
       "      <td>-0.316469</td>\n",
       "      <td>-0.079329</td>\n",
       "      <td>0.070912</td>\n",
       "      <td>-0.132105</td>\n",
       "      <td>-0.009244</td>\n",
       "      <td>0.151050</td>\n",
       "      <td>-0.079498</td>\n",
       "      <td>-0.048807</td>\n",
       "      <td>-0.207856</td>\n",
       "      <td>-0.036181</td>\n",
       "      <td>-0.060802</td>\n",
       "      <td>0.062600</td>\n",
       "      <td>0.129042</td>\n",
       "      <td>-0.139074</td>\n",
       "      <td>0.310381</td>\n",
       "      <td>-0.097736</td>\n",
       "      <td>0.152451</td>\n",
       "      <td>-0.305469</td>\n",
       "      <td>0.069221</td>\n",
       "      <td>0.137120</td>\n",
       "      <td>-0.135764</td>\n",
       "      <td>0.433612</td>\n",
       "      <td>-0.017008</td>\n",
       "      <td>0.039403</td>\n",
       "      <td>-0.203412</td>\n",
       "      <td>-0.054635</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.269408</td>\n",
       "      <td>-0.143549</td>\n",
       "      <td>0.283143</td>\n",
       "      <td>-0.004776</td>\n",
       "      <td>-0.062685</td>\n",
       "      <td>0.133809</td>\n",
       "      <td>0.033932</td>\n",
       "      <td>0.047367</td>\n",
       "      <td>0.329623</td>\n",
       "      <td>0.135072</td>\n",
       "      <td>-0.037661</td>\n",
       "      <td>0.074512</td>\n",
       "      <td>0.027695</td>\n",
       "      <td>0.104189</td>\n",
       "      <td>0.026622</td>\n",
       "      <td>0.066428</td>\n",
       "      <td>-0.113747</td>\n",
       "      <td>0.263858</td>\n",
       "      <td>-0.121201</td>\n",
       "      <td>0.010072</td>\n",
       "      <td>-0.256017</td>\n",
       "      <td>-0.060592</td>\n",
       "      <td>-0.097629</td>\n",
       "      <td>-0.164075</td>\n",
       "      <td>0.268416</td>\n",
       "      <td>-0.001478</td>\n",
       "      <td>0.174371</td>\n",
       "      <td>-0.048899</td>\n",
       "      <td>0.007231</td>\n",
       "      <td>-0.057600</td>\n",
       "      <td>0.130398</td>\n",
       "      <td>0.095052</td>\n",
       "      <td>-0.087395</td>\n",
       "      <td>-0.093361</td>\n",
       "      <td>-0.175921</td>\n",
       "      <td>-0.019632</td>\n",
       "      <td>0.030057</td>\n",
       "      <td>-0.268257</td>\n",
       "      <td>-0.003124</td>\n",
       "      <td>-0.005265</td>\n",
       "      <td>-0.100395</td>\n",
       "      <td>-0.043842</td>\n",
       "      <td>0.144827</td>\n",
       "      <td>-0.125664</td>\n",
       "      <td>0.134358</td>\n",
       "      <td>-0.157067</td>\n",
       "      <td>0.040382</td>\n",
       "      <td>0.030294</td>\n",
       "      <td>-0.248444</td>\n",
       "      <td>0.020361</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>0.148965</td>\n",
       "      <td>-0.141826</td>\n",
       "      <td>-0.064849</td>\n",
       "      <td>0.198645</td>\n",
       "      <td>-0.237333</td>\n",
       "      <td>0.096351</td>\n",
       "      <td>-0.192772</td>\n",
       "      <td>0.201036</td>\n",
       "      <td>-0.055550</td>\n",
       "      <td>0.323271</td>\n",
       "      <td>-0.124018</td>\n",
       "      <td>-0.064344</td>\n",
       "      <td>0.264262</td>\n",
       "      <td>0.229667</td>\n",
       "      <td>0.133730</td>\n",
       "      <td>-0.068402</td>\n",
       "      <td>0.067398</td>\n",
       "      <td>-0.159482</td>\n",
       "      <td>0.138655</td>\n",
       "      <td>0.017392</td>\n",
       "      <td>-0.027659</td>\n",
       "      <td>0.068616</td>\n",
       "      <td>-0.278606</td>\n",
       "      <td>0.146272</td>\n",
       "      <td>-0.246894</td>\n",
       "      <td>0.013924</td>\n",
       "      <td>0.095527</td>\n",
       "      <td>-0.171700</td>\n",
       "      <td>0.061878</td>\n",
       "      <td>0.200426</td>\n",
       "      <td>-0.122619</td>\n",
       "      <td>-0.051666</td>\n",
       "      <td>-0.242424</td>\n",
       "      <td>-0.073361</td>\n",
       "      <td>-0.049876</td>\n",
       "      <td>-0.040541</td>\n",
       "      <td>0.204453</td>\n",
       "      <td>-0.116795</td>\n",
       "      <td>0.322868</td>\n",
       "      <td>-0.009307</td>\n",
       "      <td>0.217903</td>\n",
       "      <td>-0.199481</td>\n",
       "      <td>0.109172</td>\n",
       "      <td>0.160647</td>\n",
       "      <td>-0.063116</td>\n",
       "      <td>0.359294</td>\n",
       "      <td>-0.020825</td>\n",
       "      <td>0.074966</td>\n",
       "      <td>-0.214306</td>\n",
       "      <td>-0.116703</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.260055</td>\n",
       "      <td>-0.118459</td>\n",
       "      <td>0.234262</td>\n",
       "      <td>-0.043266</td>\n",
       "      <td>-0.015988</td>\n",
       "      <td>0.069662</td>\n",
       "      <td>-0.075061</td>\n",
       "      <td>0.032331</td>\n",
       "      <td>0.287921</td>\n",
       "      <td>0.133465</td>\n",
       "      <td>-0.023363</td>\n",
       "      <td>0.062305</td>\n",
       "      <td>0.053233</td>\n",
       "      <td>0.157918</td>\n",
       "      <td>0.067226</td>\n",
       "      <td>0.141121</td>\n",
       "      <td>-0.213522</td>\n",
       "      <td>0.284241</td>\n",
       "      <td>-0.094832</td>\n",
       "      <td>0.043942</td>\n",
       "      <td>-0.210025</td>\n",
       "      <td>-0.034361</td>\n",
       "      <td>-0.037393</td>\n",
       "      <td>-0.153350</td>\n",
       "      <td>0.274964</td>\n",
       "      <td>0.005359</td>\n",
       "      <td>0.149463</td>\n",
       "      <td>0.052720</td>\n",
       "      <td>0.061115</td>\n",
       "      <td>0.042184</td>\n",
       "      <td>0.146574</td>\n",
       "      <td>0.046502</td>\n",
       "      <td>-0.084317</td>\n",
       "      <td>-0.089578</td>\n",
       "      <td>-0.209848</td>\n",
       "      <td>-0.013258</td>\n",
       "      <td>0.062758</td>\n",
       "      <td>-0.244171</td>\n",
       "      <td>-0.032025</td>\n",
       "      <td>-0.044478</td>\n",
       "      <td>-0.108473</td>\n",
       "      <td>-0.066790</td>\n",
       "      <td>0.079047</td>\n",
       "      <td>-0.211575</td>\n",
       "      <td>0.114173</td>\n",
       "      <td>-0.089037</td>\n",
       "      <td>0.146931</td>\n",
       "      <td>0.012782</td>\n",
       "      <td>-0.173229</td>\n",
       "      <td>0.016016</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5</th>\n",
       "      <td>0.136004</td>\n",
       "      <td>-0.134993</td>\n",
       "      <td>-0.085685</td>\n",
       "      <td>0.211411</td>\n",
       "      <td>-0.225582</td>\n",
       "      <td>0.071981</td>\n",
       "      <td>-0.150991</td>\n",
       "      <td>0.161480</td>\n",
       "      <td>-0.096064</td>\n",
       "      <td>0.351003</td>\n",
       "      <td>-0.141241</td>\n",
       "      <td>-0.127765</td>\n",
       "      <td>0.251382</td>\n",
       "      <td>0.145000</td>\n",
       "      <td>0.113196</td>\n",
       "      <td>-0.067518</td>\n",
       "      <td>0.019432</td>\n",
       "      <td>-0.200183</td>\n",
       "      <td>0.112800</td>\n",
       "      <td>0.025399</td>\n",
       "      <td>0.042380</td>\n",
       "      <td>0.043313</td>\n",
       "      <td>-0.374516</td>\n",
       "      <td>0.148690</td>\n",
       "      <td>-0.285326</td>\n",
       "      <td>-0.031373</td>\n",
       "      <td>0.026149</td>\n",
       "      <td>-0.138682</td>\n",
       "      <td>0.048825</td>\n",
       "      <td>0.275923</td>\n",
       "      <td>-0.126320</td>\n",
       "      <td>-0.067819</td>\n",
       "      <td>-0.266768</td>\n",
       "      <td>-0.106991</td>\n",
       "      <td>-0.066906</td>\n",
       "      <td>0.012900</td>\n",
       "      <td>0.148005</td>\n",
       "      <td>-0.067439</td>\n",
       "      <td>0.411065</td>\n",
       "      <td>0.014621</td>\n",
       "      <td>0.208669</td>\n",
       "      <td>-0.291705</td>\n",
       "      <td>0.108402</td>\n",
       "      <td>0.089902</td>\n",
       "      <td>-0.058351</td>\n",
       "      <td>0.406005</td>\n",
       "      <td>-0.067683</td>\n",
       "      <td>0.007932</td>\n",
       "      <td>-0.272992</td>\n",
       "      <td>-0.127593</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.182674</td>\n",
       "      <td>-0.099033</td>\n",
       "      <td>0.309982</td>\n",
       "      <td>-0.069400</td>\n",
       "      <td>-0.068808</td>\n",
       "      <td>0.061834</td>\n",
       "      <td>-0.050274</td>\n",
       "      <td>0.053250</td>\n",
       "      <td>0.308235</td>\n",
       "      <td>0.183944</td>\n",
       "      <td>0.006391</td>\n",
       "      <td>-0.007350</td>\n",
       "      <td>0.064807</td>\n",
       "      <td>0.175300</td>\n",
       "      <td>-0.026430</td>\n",
       "      <td>0.075535</td>\n",
       "      <td>-0.168621</td>\n",
       "      <td>0.236126</td>\n",
       "      <td>-0.101624</td>\n",
       "      <td>0.068230</td>\n",
       "      <td>-0.302349</td>\n",
       "      <td>0.001756</td>\n",
       "      <td>-0.097639</td>\n",
       "      <td>-0.194145</td>\n",
       "      <td>0.320079</td>\n",
       "      <td>-0.000449</td>\n",
       "      <td>0.193450</td>\n",
       "      <td>0.014595</td>\n",
       "      <td>0.011658</td>\n",
       "      <td>0.052489</td>\n",
       "      <td>0.116170</td>\n",
       "      <td>0.064921</td>\n",
       "      <td>-0.122043</td>\n",
       "      <td>-0.173016</td>\n",
       "      <td>-0.262249</td>\n",
       "      <td>-0.005773</td>\n",
       "      <td>0.038935</td>\n",
       "      <td>-0.247544</td>\n",
       "      <td>-0.086278</td>\n",
       "      <td>0.006853</td>\n",
       "      <td>-0.100689</td>\n",
       "      <td>-0.017608</td>\n",
       "      <td>0.153820</td>\n",
       "      <td>-0.266238</td>\n",
       "      <td>0.062926</td>\n",
       "      <td>-0.137164</td>\n",
       "      <td>0.161819</td>\n",
       "      <td>0.056334</td>\n",
       "      <td>-0.224642</td>\n",
       "      <td>-0.034494</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6</th>\n",
       "      <td>0.151536</td>\n",
       "      <td>-0.104399</td>\n",
       "      <td>-0.094527</td>\n",
       "      <td>0.160598</td>\n",
       "      <td>-0.209911</td>\n",
       "      <td>0.098383</td>\n",
       "      <td>-0.125450</td>\n",
       "      <td>0.240652</td>\n",
       "      <td>-0.009341</td>\n",
       "      <td>0.356902</td>\n",
       "      <td>-0.134509</td>\n",
       "      <td>-0.037678</td>\n",
       "      <td>0.257703</td>\n",
       "      <td>0.251786</td>\n",
       "      <td>0.107666</td>\n",
       "      <td>-0.069779</td>\n",
       "      <td>0.049223</td>\n",
       "      <td>-0.130719</td>\n",
       "      <td>0.139372</td>\n",
       "      <td>-0.011803</td>\n",
       "      <td>0.011799</td>\n",
       "      <td>0.043847</td>\n",
       "      <td>-0.303011</td>\n",
       "      <td>0.056028</td>\n",
       "      <td>-0.282500</td>\n",
       "      <td>0.017496</td>\n",
       "      <td>0.102216</td>\n",
       "      <td>-0.225272</td>\n",
       "      <td>0.071203</td>\n",
       "      <td>0.222345</td>\n",
       "      <td>-0.170881</td>\n",
       "      <td>-0.041774</td>\n",
       "      <td>-0.247629</td>\n",
       "      <td>-0.096048</td>\n",
       "      <td>-0.079126</td>\n",
       "      <td>-0.057848</td>\n",
       "      <td>0.188629</td>\n",
       "      <td>-0.075652</td>\n",
       "      <td>0.259454</td>\n",
       "      <td>0.031267</td>\n",
       "      <td>0.196929</td>\n",
       "      <td>-0.156773</td>\n",
       "      <td>0.066318</td>\n",
       "      <td>0.127572</td>\n",
       "      <td>-0.083622</td>\n",
       "      <td>0.329473</td>\n",
       "      <td>-0.018745</td>\n",
       "      <td>0.091129</td>\n",
       "      <td>-0.179197</td>\n",
       "      <td>-0.081764</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.301071</td>\n",
       "      <td>-0.092557</td>\n",
       "      <td>0.231172</td>\n",
       "      <td>-0.037784</td>\n",
       "      <td>-0.001100</td>\n",
       "      <td>0.045742</td>\n",
       "      <td>-0.048358</td>\n",
       "      <td>0.065763</td>\n",
       "      <td>0.296345</td>\n",
       "      <td>0.181686</td>\n",
       "      <td>-0.010035</td>\n",
       "      <td>0.026769</td>\n",
       "      <td>0.035602</td>\n",
       "      <td>0.172235</td>\n",
       "      <td>0.089814</td>\n",
       "      <td>0.104018</td>\n",
       "      <td>-0.243346</td>\n",
       "      <td>0.248145</td>\n",
       "      <td>-0.103823</td>\n",
       "      <td>0.030160</td>\n",
       "      <td>-0.257891</td>\n",
       "      <td>-0.001675</td>\n",
       "      <td>-0.030990</td>\n",
       "      <td>-0.161538</td>\n",
       "      <td>0.265801</td>\n",
       "      <td>0.018294</td>\n",
       "      <td>0.182558</td>\n",
       "      <td>0.102929</td>\n",
       "      <td>0.048266</td>\n",
       "      <td>0.041814</td>\n",
       "      <td>0.148157</td>\n",
       "      <td>0.009825</td>\n",
       "      <td>-0.118947</td>\n",
       "      <td>-0.064301</td>\n",
       "      <td>-0.207114</td>\n",
       "      <td>0.008509</td>\n",
       "      <td>0.032465</td>\n",
       "      <td>-0.216733</td>\n",
       "      <td>-0.016382</td>\n",
       "      <td>-0.041606</td>\n",
       "      <td>-0.074308</td>\n",
       "      <td>-0.100192</td>\n",
       "      <td>0.048829</td>\n",
       "      <td>-0.188612</td>\n",
       "      <td>0.054384</td>\n",
       "      <td>-0.127758</td>\n",
       "      <td>0.144316</td>\n",
       "      <td>0.012221</td>\n",
       "      <td>-0.232318</td>\n",
       "      <td>0.039383</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>7</th>\n",
       "      <td>0.145099</td>\n",
       "      <td>-0.090502</td>\n",
       "      <td>-0.107709</td>\n",
       "      <td>0.195208</td>\n",
       "      <td>-0.211850</td>\n",
       "      <td>0.060215</td>\n",
       "      <td>-0.166285</td>\n",
       "      <td>0.217053</td>\n",
       "      <td>-0.059384</td>\n",
       "      <td>0.314212</td>\n",
       "      <td>-0.121815</td>\n",
       "      <td>-0.083672</td>\n",
       "      <td>0.243515</td>\n",
       "      <td>0.253559</td>\n",
       "      <td>0.178009</td>\n",
       "      <td>-0.088017</td>\n",
       "      <td>0.107953</td>\n",
       "      <td>-0.154144</td>\n",
       "      <td>0.077842</td>\n",
       "      <td>0.010119</td>\n",
       "      <td>-0.017940</td>\n",
       "      <td>0.051884</td>\n",
       "      <td>-0.242562</td>\n",
       "      <td>0.081285</td>\n",
       "      <td>-0.289248</td>\n",
       "      <td>-0.005200</td>\n",
       "      <td>0.085861</td>\n",
       "      <td>-0.171394</td>\n",
       "      <td>0.031988</td>\n",
       "      <td>0.169021</td>\n",
       "      <td>-0.132753</td>\n",
       "      <td>-0.092317</td>\n",
       "      <td>-0.195003</td>\n",
       "      <td>-0.089841</td>\n",
       "      <td>-0.056232</td>\n",
       "      <td>-0.006460</td>\n",
       "      <td>0.152259</td>\n",
       "      <td>-0.090605</td>\n",
       "      <td>0.322471</td>\n",
       "      <td>-0.066294</td>\n",
       "      <td>0.193915</td>\n",
       "      <td>-0.225634</td>\n",
       "      <td>0.075350</td>\n",
       "      <td>0.118398</td>\n",
       "      <td>-0.121993</td>\n",
       "      <td>0.414488</td>\n",
       "      <td>-0.006090</td>\n",
       "      <td>0.071920</td>\n",
       "      <td>-0.198899</td>\n",
       "      <td>-0.075773</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.261415</td>\n",
       "      <td>-0.149096</td>\n",
       "      <td>0.266664</td>\n",
       "      <td>-0.022508</td>\n",
       "      <td>-0.064983</td>\n",
       "      <td>0.061168</td>\n",
       "      <td>-0.002293</td>\n",
       "      <td>0.071659</td>\n",
       "      <td>0.354536</td>\n",
       "      <td>0.129104</td>\n",
       "      <td>0.002916</td>\n",
       "      <td>0.093137</td>\n",
       "      <td>0.011172</td>\n",
       "      <td>0.151138</td>\n",
       "      <td>0.058742</td>\n",
       "      <td>0.101249</td>\n",
       "      <td>-0.190376</td>\n",
       "      <td>0.311007</td>\n",
       "      <td>-0.093571</td>\n",
       "      <td>0.031113</td>\n",
       "      <td>-0.295002</td>\n",
       "      <td>-0.060635</td>\n",
       "      <td>-0.131228</td>\n",
       "      <td>-0.106346</td>\n",
       "      <td>0.236142</td>\n",
       "      <td>0.037638</td>\n",
       "      <td>0.185169</td>\n",
       "      <td>0.066991</td>\n",
       "      <td>0.055538</td>\n",
       "      <td>-0.039351</td>\n",
       "      <td>0.137819</td>\n",
       "      <td>0.030294</td>\n",
       "      <td>-0.101123</td>\n",
       "      <td>-0.116395</td>\n",
       "      <td>-0.183114</td>\n",
       "      <td>-0.004973</td>\n",
       "      <td>0.041888</td>\n",
       "      <td>-0.145989</td>\n",
       "      <td>0.031941</td>\n",
       "      <td>0.008971</td>\n",
       "      <td>-0.085494</td>\n",
       "      <td>-0.067918</td>\n",
       "      <td>0.110396</td>\n",
       "      <td>-0.136078</td>\n",
       "      <td>0.158490</td>\n",
       "      <td>-0.114540</td>\n",
       "      <td>0.084611</td>\n",
       "      <td>0.035289</td>\n",
       "      <td>-0.215635</td>\n",
       "      <td>-0.013522</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>8</th>\n",
       "      <td>0.103065</td>\n",
       "      <td>-0.160759</td>\n",
       "      <td>-0.118862</td>\n",
       "      <td>0.199997</td>\n",
       "      <td>-0.200806</td>\n",
       "      <td>0.045798</td>\n",
       "      <td>-0.140664</td>\n",
       "      <td>0.254719</td>\n",
       "      <td>-0.080516</td>\n",
       "      <td>0.320600</td>\n",
       "      <td>-0.147457</td>\n",
       "      <td>-0.093887</td>\n",
       "      <td>0.218694</td>\n",
       "      <td>0.210146</td>\n",
       "      <td>0.162665</td>\n",
       "      <td>-0.084233</td>\n",
       "      <td>0.120447</td>\n",
       "      <td>-0.172108</td>\n",
       "      <td>0.132196</td>\n",
       "      <td>0.033965</td>\n",
       "      <td>0.058434</td>\n",
       "      <td>0.072425</td>\n",
       "      <td>-0.309210</td>\n",
       "      <td>0.125021</td>\n",
       "      <td>-0.286596</td>\n",
       "      <td>-0.035912</td>\n",
       "      <td>0.067374</td>\n",
       "      <td>-0.176865</td>\n",
       "      <td>-0.003582</td>\n",
       "      <td>0.136112</td>\n",
       "      <td>-0.102970</td>\n",
       "      <td>-0.020262</td>\n",
       "      <td>-0.254946</td>\n",
       "      <td>-0.071851</td>\n",
       "      <td>-0.094417</td>\n",
       "      <td>0.005748</td>\n",
       "      <td>0.146481</td>\n",
       "      <td>-0.095382</td>\n",
       "      <td>0.371635</td>\n",
       "      <td>-0.088203</td>\n",
       "      <td>0.228230</td>\n",
       "      <td>-0.282255</td>\n",
       "      <td>0.097140</td>\n",
       "      <td>0.125881</td>\n",
       "      <td>-0.058326</td>\n",
       "      <td>0.423827</td>\n",
       "      <td>-0.029999</td>\n",
       "      <td>0.086932</td>\n",
       "      <td>-0.267964</td>\n",
       "      <td>-0.059555</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.190497</td>\n",
       "      <td>-0.068796</td>\n",
       "      <td>0.273971</td>\n",
       "      <td>-0.119400</td>\n",
       "      <td>-0.072194</td>\n",
       "      <td>0.062293</td>\n",
       "      <td>-0.018965</td>\n",
       "      <td>0.048422</td>\n",
       "      <td>0.312787</td>\n",
       "      <td>0.148791</td>\n",
       "      <td>-0.020733</td>\n",
       "      <td>0.077878</td>\n",
       "      <td>0.046454</td>\n",
       "      <td>0.158741</td>\n",
       "      <td>0.022928</td>\n",
       "      <td>0.045851</td>\n",
       "      <td>-0.156927</td>\n",
       "      <td>0.236114</td>\n",
       "      <td>-0.098881</td>\n",
       "      <td>0.082307</td>\n",
       "      <td>-0.238682</td>\n",
       "      <td>0.003726</td>\n",
       "      <td>-0.033571</td>\n",
       "      <td>-0.180282</td>\n",
       "      <td>0.244027</td>\n",
       "      <td>0.053281</td>\n",
       "      <td>0.146560</td>\n",
       "      <td>-0.013748</td>\n",
       "      <td>0.045135</td>\n",
       "      <td>-0.036612</td>\n",
       "      <td>0.139834</td>\n",
       "      <td>0.031850</td>\n",
       "      <td>-0.132258</td>\n",
       "      <td>-0.127275</td>\n",
       "      <td>-0.238495</td>\n",
       "      <td>-0.023704</td>\n",
       "      <td>-0.005413</td>\n",
       "      <td>-0.196804</td>\n",
       "      <td>-0.020632</td>\n",
       "      <td>-0.016803</td>\n",
       "      <td>-0.110347</td>\n",
       "      <td>-0.053039</td>\n",
       "      <td>0.131506</td>\n",
       "      <td>-0.230248</td>\n",
       "      <td>0.093026</td>\n",
       "      <td>-0.131159</td>\n",
       "      <td>0.117692</td>\n",
       "      <td>0.063887</td>\n",
       "      <td>-0.195390</td>\n",
       "      <td>0.012722</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>9</th>\n",
       "      <td>0.099343</td>\n",
       "      <td>-0.111603</td>\n",
       "      <td>-0.109638</td>\n",
       "      <td>0.198031</td>\n",
       "      <td>-0.213136</td>\n",
       "      <td>0.085389</td>\n",
       "      <td>-0.112029</td>\n",
       "      <td>0.204092</td>\n",
       "      <td>-0.058360</td>\n",
       "      <td>0.277055</td>\n",
       "      <td>-0.155110</td>\n",
       "      <td>-0.102247</td>\n",
       "      <td>0.266241</td>\n",
       "      <td>0.212752</td>\n",
       "      <td>0.126143</td>\n",
       "      <td>-0.067549</td>\n",
       "      <td>0.095852</td>\n",
       "      <td>-0.139087</td>\n",
       "      <td>0.140236</td>\n",
       "      <td>0.008245</td>\n",
       "      <td>0.053534</td>\n",
       "      <td>0.068318</td>\n",
       "      <td>-0.313729</td>\n",
       "      <td>0.115662</td>\n",
       "      <td>-0.302197</td>\n",
       "      <td>-0.070243</td>\n",
       "      <td>0.075967</td>\n",
       "      <td>-0.139530</td>\n",
       "      <td>-0.007760</td>\n",
       "      <td>0.187956</td>\n",
       "      <td>-0.075757</td>\n",
       "      <td>-0.029322</td>\n",
       "      <td>-0.205248</td>\n",
       "      <td>-0.109351</td>\n",
       "      <td>-0.082544</td>\n",
       "      <td>-0.012243</td>\n",
       "      <td>0.133883</td>\n",
       "      <td>-0.092317</td>\n",
       "      <td>0.335809</td>\n",
       "      <td>-0.063369</td>\n",
       "      <td>0.206054</td>\n",
       "      <td>-0.269107</td>\n",
       "      <td>0.088131</td>\n",
       "      <td>0.130078</td>\n",
       "      <td>-0.077731</td>\n",
       "      <td>0.450993</td>\n",
       "      <td>0.002878</td>\n",
       "      <td>0.051389</td>\n",
       "      <td>-0.187067</td>\n",
       "      <td>-0.116780</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.250905</td>\n",
       "      <td>-0.153527</td>\n",
       "      <td>0.213915</td>\n",
       "      <td>-0.057285</td>\n",
       "      <td>-0.063084</td>\n",
       "      <td>0.109684</td>\n",
       "      <td>-0.017103</td>\n",
       "      <td>0.047597</td>\n",
       "      <td>0.326154</td>\n",
       "      <td>0.176828</td>\n",
       "      <td>-0.023413</td>\n",
       "      <td>0.065649</td>\n",
       "      <td>0.011750</td>\n",
       "      <td>0.079532</td>\n",
       "      <td>-0.002222</td>\n",
       "      <td>0.054662</td>\n",
       "      <td>-0.154906</td>\n",
       "      <td>0.264301</td>\n",
       "      <td>-0.128794</td>\n",
       "      <td>0.037420</td>\n",
       "      <td>-0.215849</td>\n",
       "      <td>-0.036923</td>\n",
       "      <td>-0.058880</td>\n",
       "      <td>-0.197312</td>\n",
       "      <td>0.261615</td>\n",
       "      <td>-0.006346</td>\n",
       "      <td>0.151438</td>\n",
       "      <td>-0.019252</td>\n",
       "      <td>0.027678</td>\n",
       "      <td>-0.064517</td>\n",
       "      <td>0.124614</td>\n",
       "      <td>0.055628</td>\n",
       "      <td>-0.082036</td>\n",
       "      <td>-0.137448</td>\n",
       "      <td>-0.224881</td>\n",
       "      <td>-0.027614</td>\n",
       "      <td>-0.000833</td>\n",
       "      <td>-0.208443</td>\n",
       "      <td>-0.011556</td>\n",
       "      <td>0.006449</td>\n",
       "      <td>-0.117023</td>\n",
       "      <td>-0.040955</td>\n",
       "      <td>0.128325</td>\n",
       "      <td>-0.189285</td>\n",
       "      <td>0.113435</td>\n",
       "      <td>-0.139380</td>\n",
       "      <td>0.119606</td>\n",
       "      <td>0.068152</td>\n",
       "      <td>-0.199516</td>\n",
       "      <td>-0.006351</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>0.150078</td>\n",
       "      <td>-0.164752</td>\n",
       "      <td>-0.139190</td>\n",
       "      <td>0.164668</td>\n",
       "      <td>-0.218874</td>\n",
       "      <td>0.124772</td>\n",
       "      <td>-0.087845</td>\n",
       "      <td>0.302462</td>\n",
       "      <td>-0.020091</td>\n",
       "      <td>0.354497</td>\n",
       "      <td>-0.107631</td>\n",
       "      <td>-0.065878</td>\n",
       "      <td>0.178369</td>\n",
       "      <td>0.231036</td>\n",
       "      <td>0.141611</td>\n",
       "      <td>-0.089268</td>\n",
       "      <td>0.100422</td>\n",
       "      <td>-0.203566</td>\n",
       "      <td>0.096538</td>\n",
       "      <td>0.008184</td>\n",
       "      <td>0.036038</td>\n",
       "      <td>0.021989</td>\n",
       "      <td>-0.362100</td>\n",
       "      <td>0.102716</td>\n",
       "      <td>-0.228419</td>\n",
       "      <td>-0.006532</td>\n",
       "      <td>0.073238</td>\n",
       "      <td>-0.176172</td>\n",
       "      <td>0.070957</td>\n",
       "      <td>0.147334</td>\n",
       "      <td>-0.135310</td>\n",
       "      <td>-0.024889</td>\n",
       "      <td>-0.274770</td>\n",
       "      <td>-0.033369</td>\n",
       "      <td>-0.065689</td>\n",
       "      <td>0.014031</td>\n",
       "      <td>0.190904</td>\n",
       "      <td>-0.016036</td>\n",
       "      <td>0.353996</td>\n",
       "      <td>0.010716</td>\n",
       "      <td>0.127578</td>\n",
       "      <td>-0.161569</td>\n",
       "      <td>0.018056</td>\n",
       "      <td>0.134625</td>\n",
       "      <td>-0.076073</td>\n",
       "      <td>0.344225</td>\n",
       "      <td>-0.042800</td>\n",
       "      <td>0.106303</td>\n",
       "      <td>-0.222892</td>\n",
       "      <td>-0.088620</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.298009</td>\n",
       "      <td>-0.144015</td>\n",
       "      <td>0.243391</td>\n",
       "      <td>-0.131867</td>\n",
       "      <td>-0.040785</td>\n",
       "      <td>0.091701</td>\n",
       "      <td>-0.007022</td>\n",
       "      <td>0.110253</td>\n",
       "      <td>0.235266</td>\n",
       "      <td>0.162594</td>\n",
       "      <td>0.044592</td>\n",
       "      <td>-0.040522</td>\n",
       "      <td>0.036766</td>\n",
       "      <td>0.204389</td>\n",
       "      <td>0.099569</td>\n",
       "      <td>0.043105</td>\n",
       "      <td>-0.204846</td>\n",
       "      <td>0.250286</td>\n",
       "      <td>-0.110963</td>\n",
       "      <td>-0.033590</td>\n",
       "      <td>-0.304709</td>\n",
       "      <td>0.004935</td>\n",
       "      <td>-0.061459</td>\n",
       "      <td>-0.125348</td>\n",
       "      <td>0.276709</td>\n",
       "      <td>0.053173</td>\n",
       "      <td>0.240315</td>\n",
       "      <td>-0.028827</td>\n",
       "      <td>0.071875</td>\n",
       "      <td>0.023344</td>\n",
       "      <td>0.088318</td>\n",
       "      <td>0.024818</td>\n",
       "      <td>-0.136321</td>\n",
       "      <td>-0.045837</td>\n",
       "      <td>-0.200750</td>\n",
       "      <td>0.005410</td>\n",
       "      <td>-0.037325</td>\n",
       "      <td>-0.247657</td>\n",
       "      <td>0.048043</td>\n",
       "      <td>0.020175</td>\n",
       "      <td>-0.046009</td>\n",
       "      <td>-0.168293</td>\n",
       "      <td>0.039751</td>\n",
       "      <td>-0.207008</td>\n",
       "      <td>0.099637</td>\n",
       "      <td>-0.132462</td>\n",
       "      <td>0.100105</td>\n",
       "      <td>0.048275</td>\n",
       "      <td>-0.188483</td>\n",
       "      <td>-0.005470</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>11</th>\n",
       "      <td>0.115792</td>\n",
       "      <td>-0.108504</td>\n",
       "      <td>-0.095944</td>\n",
       "      <td>0.201081</td>\n",
       "      <td>-0.214380</td>\n",
       "      <td>0.148985</td>\n",
       "      <td>-0.134413</td>\n",
       "      <td>0.193465</td>\n",
       "      <td>-0.050984</td>\n",
       "      <td>0.317283</td>\n",
       "      <td>-0.157609</td>\n",
       "      <td>-0.077027</td>\n",
       "      <td>0.272274</td>\n",
       "      <td>0.131107</td>\n",
       "      <td>0.122000</td>\n",
       "      <td>-0.118348</td>\n",
       "      <td>-0.028966</td>\n",
       "      <td>-0.129934</td>\n",
       "      <td>0.200150</td>\n",
       "      <td>-0.009556</td>\n",
       "      <td>0.055637</td>\n",
       "      <td>0.031063</td>\n",
       "      <td>-0.383756</td>\n",
       "      <td>0.095411</td>\n",
       "      <td>-0.241722</td>\n",
       "      <td>0.010062</td>\n",
       "      <td>0.083183</td>\n",
       "      <td>-0.208177</td>\n",
       "      <td>0.041552</td>\n",
       "      <td>0.224658</td>\n",
       "      <td>-0.118344</td>\n",
       "      <td>-0.033593</td>\n",
       "      <td>-0.270024</td>\n",
       "      <td>-0.121885</td>\n",
       "      <td>-0.039426</td>\n",
       "      <td>-0.045207</td>\n",
       "      <td>0.149154</td>\n",
       "      <td>-0.069405</td>\n",
       "      <td>0.308419</td>\n",
       "      <td>0.013589</td>\n",
       "      <td>0.164959</td>\n",
       "      <td>-0.254017</td>\n",
       "      <td>0.102697</td>\n",
       "      <td>0.150631</td>\n",
       "      <td>-0.055280</td>\n",
       "      <td>0.373151</td>\n",
       "      <td>-0.062987</td>\n",
       "      <td>0.061949</td>\n",
       "      <td>-0.196161</td>\n",
       "      <td>-0.158728</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.315751</td>\n",
       "      <td>-0.188674</td>\n",
       "      <td>0.246871</td>\n",
       "      <td>-0.124228</td>\n",
       "      <td>0.002425</td>\n",
       "      <td>0.067850</td>\n",
       "      <td>-0.058481</td>\n",
       "      <td>0.090214</td>\n",
       "      <td>0.242821</td>\n",
       "      <td>0.205145</td>\n",
       "      <td>0.015614</td>\n",
       "      <td>-0.038904</td>\n",
       "      <td>0.020816</td>\n",
       "      <td>0.153461</td>\n",
       "      <td>0.037507</td>\n",
       "      <td>0.081769</td>\n",
       "      <td>-0.236578</td>\n",
       "      <td>0.270648</td>\n",
       "      <td>-0.114520</td>\n",
       "      <td>-0.011366</td>\n",
       "      <td>-0.254067</td>\n",
       "      <td>-0.045520</td>\n",
       "      <td>-0.091991</td>\n",
       "      <td>-0.154352</td>\n",
       "      <td>0.287787</td>\n",
       "      <td>0.030450</td>\n",
       "      <td>0.196839</td>\n",
       "      <td>-0.006939</td>\n",
       "      <td>0.067371</td>\n",
       "      <td>-0.025671</td>\n",
       "      <td>0.105058</td>\n",
       "      <td>0.073961</td>\n",
       "      <td>-0.135288</td>\n",
       "      <td>-0.120844</td>\n",
       "      <td>-0.191466</td>\n",
       "      <td>-0.041058</td>\n",
       "      <td>-0.020177</td>\n",
       "      <td>-0.214008</td>\n",
       "      <td>-0.059341</td>\n",
       "      <td>0.029301</td>\n",
       "      <td>-0.145702</td>\n",
       "      <td>-0.075578</td>\n",
       "      <td>0.129732</td>\n",
       "      <td>-0.261438</td>\n",
       "      <td>0.101597</td>\n",
       "      <td>-0.091607</td>\n",
       "      <td>0.138630</td>\n",
       "      <td>0.073024</td>\n",
       "      <td>-0.212505</td>\n",
       "      <td>0.010496</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12</th>\n",
       "      <td>0.038375</td>\n",
       "      <td>-0.122354</td>\n",
       "      <td>-0.096294</td>\n",
       "      <td>0.185208</td>\n",
       "      <td>-0.246582</td>\n",
       "      <td>0.129750</td>\n",
       "      <td>-0.136116</td>\n",
       "      <td>0.261413</td>\n",
       "      <td>-0.050703</td>\n",
       "      <td>0.295339</td>\n",
       "      <td>-0.190413</td>\n",
       "      <td>-0.038232</td>\n",
       "      <td>0.229736</td>\n",
       "      <td>0.266636</td>\n",
       "      <td>0.218819</td>\n",
       "      <td>-0.110686</td>\n",
       "      <td>0.086804</td>\n",
       "      <td>-0.144453</td>\n",
       "      <td>0.022403</td>\n",
       "      <td>0.043655</td>\n",
       "      <td>-0.001109</td>\n",
       "      <td>0.084221</td>\n",
       "      <td>-0.197743</td>\n",
       "      <td>0.107413</td>\n",
       "      <td>-0.265296</td>\n",
       "      <td>-0.061734</td>\n",
       "      <td>0.054527</td>\n",
       "      <td>-0.105054</td>\n",
       "      <td>-0.026064</td>\n",
       "      <td>0.108197</td>\n",
       "      <td>-0.145600</td>\n",
       "      <td>-0.056957</td>\n",
       "      <td>-0.254362</td>\n",
       "      <td>-0.045438</td>\n",
       "      <td>-0.059084</td>\n",
       "      <td>0.075778</td>\n",
       "      <td>0.132040</td>\n",
       "      <td>-0.080114</td>\n",
       "      <td>0.339599</td>\n",
       "      <td>-0.111337</td>\n",
       "      <td>0.094832</td>\n",
       "      <td>-0.238816</td>\n",
       "      <td>0.056826</td>\n",
       "      <td>0.135097</td>\n",
       "      <td>-0.142426</td>\n",
       "      <td>0.373937</td>\n",
       "      <td>0.064764</td>\n",
       "      <td>0.133505</td>\n",
       "      <td>-0.192966</td>\n",
       "      <td>-0.009309</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.285787</td>\n",
       "      <td>-0.210788</td>\n",
       "      <td>0.304097</td>\n",
       "      <td>-0.035136</td>\n",
       "      <td>-0.041249</td>\n",
       "      <td>0.117025</td>\n",
       "      <td>0.081218</td>\n",
       "      <td>0.072704</td>\n",
       "      <td>0.296876</td>\n",
       "      <td>0.105401</td>\n",
       "      <td>-0.016906</td>\n",
       "      <td>0.077851</td>\n",
       "      <td>0.006812</td>\n",
       "      <td>0.164669</td>\n",
       "      <td>0.068866</td>\n",
       "      <td>0.046182</td>\n",
       "      <td>-0.106428</td>\n",
       "      <td>0.243790</td>\n",
       "      <td>-0.127053</td>\n",
       "      <td>-0.014188</td>\n",
       "      <td>-0.303799</td>\n",
       "      <td>-0.084134</td>\n",
       "      <td>-0.151635</td>\n",
       "      <td>-0.088357</td>\n",
       "      <td>0.288222</td>\n",
       "      <td>-0.035630</td>\n",
       "      <td>0.256301</td>\n",
       "      <td>-0.050371</td>\n",
       "      <td>0.009820</td>\n",
       "      <td>-0.037074</td>\n",
       "      <td>0.135655</td>\n",
       "      <td>0.072813</td>\n",
       "      <td>-0.108007</td>\n",
       "      <td>-0.074288</td>\n",
       "      <td>-0.132788</td>\n",
       "      <td>-0.031031</td>\n",
       "      <td>0.024256</td>\n",
       "      <td>-0.188304</td>\n",
       "      <td>0.069645</td>\n",
       "      <td>0.022508</td>\n",
       "      <td>-0.151514</td>\n",
       "      <td>-0.088697</td>\n",
       "      <td>0.123143</td>\n",
       "      <td>-0.146471</td>\n",
       "      <td>0.105474</td>\n",
       "      <td>-0.192358</td>\n",
       "      <td>0.039527</td>\n",
       "      <td>0.008083</td>\n",
       "      <td>-0.212721</td>\n",
       "      <td>0.027601</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13</th>\n",
       "      <td>0.120317</td>\n",
       "      <td>-0.121055</td>\n",
       "      <td>-0.064248</td>\n",
       "      <td>0.174359</td>\n",
       "      <td>-0.232488</td>\n",
       "      <td>0.117344</td>\n",
       "      <td>-0.165565</td>\n",
       "      <td>0.214395</td>\n",
       "      <td>-0.018626</td>\n",
       "      <td>0.327004</td>\n",
       "      <td>-0.119045</td>\n",
       "      <td>-0.095545</td>\n",
       "      <td>0.282013</td>\n",
       "      <td>0.219324</td>\n",
       "      <td>0.102566</td>\n",
       "      <td>-0.073750</td>\n",
       "      <td>0.030573</td>\n",
       "      <td>-0.124610</td>\n",
       "      <td>0.172989</td>\n",
       "      <td>0.024975</td>\n",
       "      <td>-0.001409</td>\n",
       "      <td>0.048996</td>\n",
       "      <td>-0.292034</td>\n",
       "      <td>0.072753</td>\n",
       "      <td>-0.271898</td>\n",
       "      <td>-0.001238</td>\n",
       "      <td>0.105216</td>\n",
       "      <td>-0.210466</td>\n",
       "      <td>0.018057</td>\n",
       "      <td>0.257754</td>\n",
       "      <td>-0.112871</td>\n",
       "      <td>-0.036326</td>\n",
       "      <td>-0.240222</td>\n",
       "      <td>-0.094845</td>\n",
       "      <td>-0.035892</td>\n",
       "      <td>-0.038089</td>\n",
       "      <td>0.175621</td>\n",
       "      <td>-0.099115</td>\n",
       "      <td>0.289955</td>\n",
       "      <td>0.017061</td>\n",
       "      <td>0.203475</td>\n",
       "      <td>-0.203858</td>\n",
       "      <td>0.095819</td>\n",
       "      <td>0.162732</td>\n",
       "      <td>-0.116114</td>\n",
       "      <td>0.338927</td>\n",
       "      <td>-0.040147</td>\n",
       "      <td>0.065871</td>\n",
       "      <td>-0.194454</td>\n",
       "      <td>-0.069315</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.220470</td>\n",
       "      <td>-0.081250</td>\n",
       "      <td>0.200649</td>\n",
       "      <td>-0.075216</td>\n",
       "      <td>-0.004152</td>\n",
       "      <td>0.034934</td>\n",
       "      <td>-0.067995</td>\n",
       "      <td>0.072879</td>\n",
       "      <td>0.305654</td>\n",
       "      <td>0.168654</td>\n",
       "      <td>-0.026132</td>\n",
       "      <td>0.025350</td>\n",
       "      <td>0.006906</td>\n",
       "      <td>0.145415</td>\n",
       "      <td>0.042224</td>\n",
       "      <td>0.104617</td>\n",
       "      <td>-0.226993</td>\n",
       "      <td>0.268139</td>\n",
       "      <td>-0.074999</td>\n",
       "      <td>0.054336</td>\n",
       "      <td>-0.209815</td>\n",
       "      <td>0.005642</td>\n",
       "      <td>-0.016829</td>\n",
       "      <td>-0.184797</td>\n",
       "      <td>0.275551</td>\n",
       "      <td>0.001305</td>\n",
       "      <td>0.134658</td>\n",
       "      <td>0.085755</td>\n",
       "      <td>0.063383</td>\n",
       "      <td>0.000179</td>\n",
       "      <td>0.122608</td>\n",
       "      <td>0.018554</td>\n",
       "      <td>-0.135003</td>\n",
       "      <td>-0.092231</td>\n",
       "      <td>-0.258658</td>\n",
       "      <td>-0.009369</td>\n",
       "      <td>0.068916</td>\n",
       "      <td>-0.240644</td>\n",
       "      <td>-0.018663</td>\n",
       "      <td>-0.034235</td>\n",
       "      <td>-0.085768</td>\n",
       "      <td>-0.125209</td>\n",
       "      <td>0.048285</td>\n",
       "      <td>-0.237905</td>\n",
       "      <td>0.089749</td>\n",
       "      <td>-0.119637</td>\n",
       "      <td>0.194365</td>\n",
       "      <td>0.030610</td>\n",
       "      <td>-0.202990</td>\n",
       "      <td>0.032436</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14</th>\n",
       "      <td>0.189981</td>\n",
       "      <td>-0.099620</td>\n",
       "      <td>-0.043858</td>\n",
       "      <td>0.121855</td>\n",
       "      <td>-0.223010</td>\n",
       "      <td>0.106480</td>\n",
       "      <td>-0.079413</td>\n",
       "      <td>0.148225</td>\n",
       "      <td>-0.104803</td>\n",
       "      <td>0.193760</td>\n",
       "      <td>-0.111376</td>\n",
       "      <td>-0.112515</td>\n",
       "      <td>0.288065</td>\n",
       "      <td>0.184379</td>\n",
       "      <td>0.237830</td>\n",
       "      <td>-0.169967</td>\n",
       "      <td>0.165410</td>\n",
       "      <td>-0.108414</td>\n",
       "      <td>0.057439</td>\n",
       "      <td>0.003095</td>\n",
       "      <td>0.084068</td>\n",
       "      <td>0.141730</td>\n",
       "      <td>-0.139191</td>\n",
       "      <td>0.122362</td>\n",
       "      <td>-0.235837</td>\n",
       "      <td>-0.069561</td>\n",
       "      <td>0.127322</td>\n",
       "      <td>-0.036462</td>\n",
       "      <td>0.000151</td>\n",
       "      <td>0.101028</td>\n",
       "      <td>-0.093296</td>\n",
       "      <td>-0.030716</td>\n",
       "      <td>-0.284957</td>\n",
       "      <td>-0.079319</td>\n",
       "      <td>-0.015006</td>\n",
       "      <td>0.072996</td>\n",
       "      <td>0.199853</td>\n",
       "      <td>-0.133236</td>\n",
       "      <td>0.325790</td>\n",
       "      <td>-0.095498</td>\n",
       "      <td>0.090839</td>\n",
       "      <td>-0.339671</td>\n",
       "      <td>0.122503</td>\n",
       "      <td>0.078338</td>\n",
       "      <td>-0.140163</td>\n",
       "      <td>0.372474</td>\n",
       "      <td>-0.001720</td>\n",
       "      <td>0.111966</td>\n",
       "      <td>-0.220115</td>\n",
       "      <td>0.040483</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.257369</td>\n",
       "      <td>-0.194803</td>\n",
       "      <td>0.289560</td>\n",
       "      <td>-0.042378</td>\n",
       "      <td>-0.035136</td>\n",
       "      <td>0.019302</td>\n",
       "      <td>-0.002439</td>\n",
       "      <td>0.037282</td>\n",
       "      <td>0.296227</td>\n",
       "      <td>0.165759</td>\n",
       "      <td>-0.087287</td>\n",
       "      <td>0.120988</td>\n",
       "      <td>-0.002333</td>\n",
       "      <td>0.152132</td>\n",
       "      <td>0.118750</td>\n",
       "      <td>-0.046699</td>\n",
       "      <td>-0.095219</td>\n",
       "      <td>0.143039</td>\n",
       "      <td>-0.134040</td>\n",
       "      <td>0.006807</td>\n",
       "      <td>-0.196759</td>\n",
       "      <td>-0.157597</td>\n",
       "      <td>-0.113838</td>\n",
       "      <td>-0.076940</td>\n",
       "      <td>0.298091</td>\n",
       "      <td>0.015936</td>\n",
       "      <td>0.143178</td>\n",
       "      <td>-0.030893</td>\n",
       "      <td>-0.096511</td>\n",
       "      <td>0.009031</td>\n",
       "      <td>0.164422</td>\n",
       "      <td>0.151125</td>\n",
       "      <td>-0.059847</td>\n",
       "      <td>-0.060007</td>\n",
       "      <td>-0.055120</td>\n",
       "      <td>-0.047606</td>\n",
       "      <td>-0.005355</td>\n",
       "      <td>-0.208166</td>\n",
       "      <td>-0.048341</td>\n",
       "      <td>0.014015</td>\n",
       "      <td>-0.160277</td>\n",
       "      <td>-0.057837</td>\n",
       "      <td>0.182498</td>\n",
       "      <td>-0.187860</td>\n",
       "      <td>0.091341</td>\n",
       "      <td>-0.235567</td>\n",
       "      <td>0.012353</td>\n",
       "      <td>-0.006476</td>\n",
       "      <td>-0.279787</td>\n",
       "      <td>0.032740</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15</th>\n",
       "      <td>0.102191</td>\n",
       "      <td>-0.099493</td>\n",
       "      <td>-0.058236</td>\n",
       "      <td>0.241401</td>\n",
       "      <td>-0.215121</td>\n",
       "      <td>0.104573</td>\n",
       "      <td>-0.169301</td>\n",
       "      <td>0.206972</td>\n",
       "      <td>-0.086058</td>\n",
       "      <td>0.281521</td>\n",
       "      <td>-0.122076</td>\n",
       "      <td>-0.138420</td>\n",
       "      <td>0.286749</td>\n",
       "      <td>0.199947</td>\n",
       "      <td>0.136107</td>\n",
       "      <td>-0.052422</td>\n",
       "      <td>-0.014880</td>\n",
       "      <td>-0.119737</td>\n",
       "      <td>0.163019</td>\n",
       "      <td>0.091869</td>\n",
       "      <td>0.008481</td>\n",
       "      <td>0.072334</td>\n",
       "      <td>-0.336468</td>\n",
       "      <td>0.129277</td>\n",
       "      <td>-0.278159</td>\n",
       "      <td>-0.006612</td>\n",
       "      <td>0.089056</td>\n",
       "      <td>-0.145332</td>\n",
       "      <td>0.032628</td>\n",
       "      <td>0.223559</td>\n",
       "      <td>-0.075726</td>\n",
       "      <td>-0.054147</td>\n",
       "      <td>-0.263812</td>\n",
       "      <td>-0.092986</td>\n",
       "      <td>-0.032027</td>\n",
       "      <td>0.065049</td>\n",
       "      <td>0.120588</td>\n",
       "      <td>-0.102302</td>\n",
       "      <td>0.383077</td>\n",
       "      <td>-0.028744</td>\n",
       "      <td>0.173533</td>\n",
       "      <td>-0.246471</td>\n",
       "      <td>0.168547</td>\n",
       "      <td>0.146214</td>\n",
       "      <td>-0.064242</td>\n",
       "      <td>0.432962</td>\n",
       "      <td>-0.061124</td>\n",
       "      <td>0.049675</td>\n",
       "      <td>-0.223034</td>\n",
       "      <td>-0.125485</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.243484</td>\n",
       "      <td>-0.139190</td>\n",
       "      <td>0.252767</td>\n",
       "      <td>-0.142362</td>\n",
       "      <td>-0.008536</td>\n",
       "      <td>0.080961</td>\n",
       "      <td>-0.019042</td>\n",
       "      <td>0.102304</td>\n",
       "      <td>0.247494</td>\n",
       "      <td>0.153022</td>\n",
       "      <td>0.029064</td>\n",
       "      <td>0.027233</td>\n",
       "      <td>0.046584</td>\n",
       "      <td>0.094876</td>\n",
       "      <td>0.003481</td>\n",
       "      <td>0.069172</td>\n",
       "      <td>-0.160779</td>\n",
       "      <td>0.253894</td>\n",
       "      <td>-0.103547</td>\n",
       "      <td>0.036547</td>\n",
       "      <td>-0.254178</td>\n",
       "      <td>-0.036223</td>\n",
       "      <td>-0.116226</td>\n",
       "      <td>-0.159439</td>\n",
       "      <td>0.312328</td>\n",
       "      <td>0.000788</td>\n",
       "      <td>0.154139</td>\n",
       "      <td>-0.069870</td>\n",
       "      <td>0.038898</td>\n",
       "      <td>-0.032237</td>\n",
       "      <td>0.123034</td>\n",
       "      <td>0.088775</td>\n",
       "      <td>-0.121829</td>\n",
       "      <td>-0.139446</td>\n",
       "      <td>-0.217131</td>\n",
       "      <td>-0.039351</td>\n",
       "      <td>0.061298</td>\n",
       "      <td>-0.263394</td>\n",
       "      <td>-0.027513</td>\n",
       "      <td>0.061093</td>\n",
       "      <td>-0.102818</td>\n",
       "      <td>-0.056086</td>\n",
       "      <td>0.127391</td>\n",
       "      <td>-0.206826</td>\n",
       "      <td>0.172474</td>\n",
       "      <td>-0.145889</td>\n",
       "      <td>0.087672</td>\n",
       "      <td>0.062160</td>\n",
       "      <td>-0.187354</td>\n",
       "      <td>-0.035439</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16</th>\n",
       "      <td>0.119033</td>\n",
       "      <td>-0.153783</td>\n",
       "      <td>-0.051925</td>\n",
       "      <td>0.181384</td>\n",
       "      <td>-0.247768</td>\n",
       "      <td>0.159741</td>\n",
       "      <td>-0.146779</td>\n",
       "      <td>0.150573</td>\n",
       "      <td>0.015509</td>\n",
       "      <td>0.325348</td>\n",
       "      <td>-0.151091</td>\n",
       "      <td>-0.096851</td>\n",
       "      <td>0.285886</td>\n",
       "      <td>0.278048</td>\n",
       "      <td>0.142507</td>\n",
       "      <td>-0.085697</td>\n",
       "      <td>0.061194</td>\n",
       "      <td>-0.082059</td>\n",
       "      <td>0.097556</td>\n",
       "      <td>0.001971</td>\n",
       "      <td>-0.051151</td>\n",
       "      <td>0.082288</td>\n",
       "      <td>-0.352009</td>\n",
       "      <td>0.068670</td>\n",
       "      <td>-0.260803</td>\n",
       "      <td>0.036818</td>\n",
       "      <td>0.115875</td>\n",
       "      <td>-0.170938</td>\n",
       "      <td>0.065302</td>\n",
       "      <td>0.159618</td>\n",
       "      <td>-0.147296</td>\n",
       "      <td>-0.025318</td>\n",
       "      <td>-0.257168</td>\n",
       "      <td>-0.087648</td>\n",
       "      <td>-0.055692</td>\n",
       "      <td>-0.037980</td>\n",
       "      <td>0.156549</td>\n",
       "      <td>-0.096878</td>\n",
       "      <td>0.307695</td>\n",
       "      <td>-0.081831</td>\n",
       "      <td>0.208126</td>\n",
       "      <td>-0.218307</td>\n",
       "      <td>0.039142</td>\n",
       "      <td>0.128212</td>\n",
       "      <td>-0.131671</td>\n",
       "      <td>0.328037</td>\n",
       "      <td>-0.018745</td>\n",
       "      <td>0.077934</td>\n",
       "      <td>-0.222961</td>\n",
       "      <td>0.014172</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.301292</td>\n",
       "      <td>-0.198801</td>\n",
       "      <td>0.266748</td>\n",
       "      <td>-0.068333</td>\n",
       "      <td>0.020373</td>\n",
       "      <td>0.050335</td>\n",
       "      <td>-0.026783</td>\n",
       "      <td>0.050628</td>\n",
       "      <td>0.320089</td>\n",
       "      <td>0.182188</td>\n",
       "      <td>-0.015136</td>\n",
       "      <td>0.074301</td>\n",
       "      <td>0.050304</td>\n",
       "      <td>0.171862</td>\n",
       "      <td>0.053688</td>\n",
       "      <td>0.054213</td>\n",
       "      <td>-0.177965</td>\n",
       "      <td>0.274620</td>\n",
       "      <td>-0.117158</td>\n",
       "      <td>0.057790</td>\n",
       "      <td>-0.260737</td>\n",
       "      <td>-0.037194</td>\n",
       "      <td>-0.067742</td>\n",
       "      <td>-0.140891</td>\n",
       "      <td>0.283212</td>\n",
       "      <td>0.033169</td>\n",
       "      <td>0.228327</td>\n",
       "      <td>0.039754</td>\n",
       "      <td>0.048385</td>\n",
       "      <td>-0.011748</td>\n",
       "      <td>0.174834</td>\n",
       "      <td>0.110390</td>\n",
       "      <td>-0.123504</td>\n",
       "      <td>-0.101839</td>\n",
       "      <td>-0.137505</td>\n",
       "      <td>-0.057028</td>\n",
       "      <td>0.076221</td>\n",
       "      <td>-0.190554</td>\n",
       "      <td>-0.003539</td>\n",
       "      <td>0.011149</td>\n",
       "      <td>-0.107161</td>\n",
       "      <td>-0.075849</td>\n",
       "      <td>0.083053</td>\n",
       "      <td>-0.151076</td>\n",
       "      <td>0.082481</td>\n",
       "      <td>-0.100382</td>\n",
       "      <td>0.139618</td>\n",
       "      <td>-0.009169</td>\n",
       "      <td>-0.223864</td>\n",
       "      <td>0.021656</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17</th>\n",
       "      <td>0.157800</td>\n",
       "      <td>-0.118686</td>\n",
       "      <td>-0.150606</td>\n",
       "      <td>0.205409</td>\n",
       "      <td>-0.242001</td>\n",
       "      <td>0.111716</td>\n",
       "      <td>-0.137265</td>\n",
       "      <td>0.180476</td>\n",
       "      <td>-0.066203</td>\n",
       "      <td>0.368237</td>\n",
       "      <td>-0.156377</td>\n",
       "      <td>-0.078210</td>\n",
       "      <td>0.206123</td>\n",
       "      <td>0.196558</td>\n",
       "      <td>0.151126</td>\n",
       "      <td>-0.077988</td>\n",
       "      <td>0.026512</td>\n",
       "      <td>-0.242836</td>\n",
       "      <td>0.100818</td>\n",
       "      <td>0.013725</td>\n",
       "      <td>0.030066</td>\n",
       "      <td>0.005728</td>\n",
       "      <td>-0.345935</td>\n",
       "      <td>0.146713</td>\n",
       "      <td>-0.295815</td>\n",
       "      <td>-0.000897</td>\n",
       "      <td>0.021820</td>\n",
       "      <td>-0.168606</td>\n",
       "      <td>0.075197</td>\n",
       "      <td>0.255719</td>\n",
       "      <td>-0.177132</td>\n",
       "      <td>-0.078953</td>\n",
       "      <td>-0.276595</td>\n",
       "      <td>-0.121217</td>\n",
       "      <td>-0.093077</td>\n",
       "      <td>-0.027708</td>\n",
       "      <td>0.203718</td>\n",
       "      <td>-0.023698</td>\n",
       "      <td>0.379397</td>\n",
       "      <td>0.052573</td>\n",
       "      <td>0.173632</td>\n",
       "      <td>-0.215421</td>\n",
       "      <td>0.052578</td>\n",
       "      <td>0.077885</td>\n",
       "      <td>-0.079277</td>\n",
       "      <td>0.334538</td>\n",
       "      <td>-0.037508</td>\n",
       "      <td>0.080958</td>\n",
       "      <td>-0.203167</td>\n",
       "      <td>-0.107945</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.305712</td>\n",
       "      <td>-0.171058</td>\n",
       "      <td>0.355773</td>\n",
       "      <td>-0.007645</td>\n",
       "      <td>-0.065319</td>\n",
       "      <td>0.074771</td>\n",
       "      <td>-0.023929</td>\n",
       "      <td>0.060666</td>\n",
       "      <td>0.297388</td>\n",
       "      <td>0.203568</td>\n",
       "      <td>0.019223</td>\n",
       "      <td>-0.004132</td>\n",
       "      <td>0.049873</td>\n",
       "      <td>0.239919</td>\n",
       "      <td>0.051372</td>\n",
       "      <td>0.073958</td>\n",
       "      <td>-0.208709</td>\n",
       "      <td>0.253077</td>\n",
       "      <td>-0.081424</td>\n",
       "      <td>-0.004213</td>\n",
       "      <td>-0.365345</td>\n",
       "      <td>-0.037336</td>\n",
       "      <td>-0.125068</td>\n",
       "      <td>-0.159977</td>\n",
       "      <td>0.312410</td>\n",
       "      <td>0.036051</td>\n",
       "      <td>0.257404</td>\n",
       "      <td>0.052406</td>\n",
       "      <td>0.045977</td>\n",
       "      <td>0.080828</td>\n",
       "      <td>0.101054</td>\n",
       "      <td>0.014985</td>\n",
       "      <td>-0.129130</td>\n",
       "      <td>-0.102880</td>\n",
       "      <td>-0.180212</td>\n",
       "      <td>0.020306</td>\n",
       "      <td>-0.054750</td>\n",
       "      <td>-0.206388</td>\n",
       "      <td>-0.034011</td>\n",
       "      <td>0.013454</td>\n",
       "      <td>-0.065365</td>\n",
       "      <td>-0.042283</td>\n",
       "      <td>0.122216</td>\n",
       "      <td>-0.206583</td>\n",
       "      <td>0.080122</td>\n",
       "      <td>-0.109054</td>\n",
       "      <td>0.087060</td>\n",
       "      <td>0.060336</td>\n",
       "      <td>-0.259084</td>\n",
       "      <td>-0.005970</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>18</th>\n",
       "      <td>0.136303</td>\n",
       "      <td>-0.061476</td>\n",
       "      <td>-0.077046</td>\n",
       "      <td>0.206502</td>\n",
       "      <td>-0.223313</td>\n",
       "      <td>0.101852</td>\n",
       "      <td>-0.162581</td>\n",
       "      <td>0.214483</td>\n",
       "      <td>-0.106981</td>\n",
       "      <td>0.300105</td>\n",
       "      <td>-0.162145</td>\n",
       "      <td>-0.066771</td>\n",
       "      <td>0.237164</td>\n",
       "      <td>0.192834</td>\n",
       "      <td>0.217991</td>\n",
       "      <td>-0.060120</td>\n",
       "      <td>0.071474</td>\n",
       "      <td>-0.123842</td>\n",
       "      <td>0.067547</td>\n",
       "      <td>0.036414</td>\n",
       "      <td>0.060337</td>\n",
       "      <td>0.096562</td>\n",
       "      <td>-0.218304</td>\n",
       "      <td>0.114091</td>\n",
       "      <td>-0.317158</td>\n",
       "      <td>-0.084755</td>\n",
       "      <td>0.087118</td>\n",
       "      <td>-0.108638</td>\n",
       "      <td>-0.033983</td>\n",
       "      <td>0.165166</td>\n",
       "      <td>-0.047793</td>\n",
       "      <td>-0.060727</td>\n",
       "      <td>-0.230026</td>\n",
       "      <td>-0.069550</td>\n",
       "      <td>-0.064082</td>\n",
       "      <td>0.063639</td>\n",
       "      <td>0.136363</td>\n",
       "      <td>-0.148054</td>\n",
       "      <td>0.353077</td>\n",
       "      <td>-0.060597</td>\n",
       "      <td>0.173821</td>\n",
       "      <td>-0.317670</td>\n",
       "      <td>0.102959</td>\n",
       "      <td>0.144486</td>\n",
       "      <td>-0.121943</td>\n",
       "      <td>0.421104</td>\n",
       "      <td>0.032542</td>\n",
       "      <td>0.045617</td>\n",
       "      <td>-0.220814</td>\n",
       "      <td>-0.068091</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.266425</td>\n",
       "      <td>-0.168228</td>\n",
       "      <td>0.279185</td>\n",
       "      <td>0.007925</td>\n",
       "      <td>-0.085837</td>\n",
       "      <td>0.134813</td>\n",
       "      <td>0.006549</td>\n",
       "      <td>0.019470</td>\n",
       "      <td>0.300920</td>\n",
       "      <td>0.140518</td>\n",
       "      <td>-0.021785</td>\n",
       "      <td>0.110521</td>\n",
       "      <td>-0.006799</td>\n",
       "      <td>0.116738</td>\n",
       "      <td>0.028755</td>\n",
       "      <td>0.046989</td>\n",
       "      <td>-0.131090</td>\n",
       "      <td>0.214290</td>\n",
       "      <td>-0.122605</td>\n",
       "      <td>0.028768</td>\n",
       "      <td>-0.244791</td>\n",
       "      <td>-0.101420</td>\n",
       "      <td>-0.156218</td>\n",
       "      <td>-0.161383</td>\n",
       "      <td>0.290095</td>\n",
       "      <td>0.033902</td>\n",
       "      <td>0.171926</td>\n",
       "      <td>-0.040112</td>\n",
       "      <td>-0.004920</td>\n",
       "      <td>-0.000114</td>\n",
       "      <td>0.094790</td>\n",
       "      <td>0.110083</td>\n",
       "      <td>-0.095803</td>\n",
       "      <td>-0.123639</td>\n",
       "      <td>-0.195949</td>\n",
       "      <td>-0.033038</td>\n",
       "      <td>0.024126</td>\n",
       "      <td>-0.255053</td>\n",
       "      <td>-0.008551</td>\n",
       "      <td>-0.006948</td>\n",
       "      <td>-0.138308</td>\n",
       "      <td>-0.010194</td>\n",
       "      <td>0.149291</td>\n",
       "      <td>-0.141397</td>\n",
       "      <td>0.155086</td>\n",
       "      <td>-0.184331</td>\n",
       "      <td>0.052950</td>\n",
       "      <td>-0.007783</td>\n",
       "      <td>-0.253648</td>\n",
       "      <td>0.059368</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19</th>\n",
       "      <td>0.139033</td>\n",
       "      <td>-0.122947</td>\n",
       "      <td>-0.111735</td>\n",
       "      <td>0.174526</td>\n",
       "      <td>-0.220552</td>\n",
       "      <td>0.051838</td>\n",
       "      <td>-0.162037</td>\n",
       "      <td>0.183666</td>\n",
       "      <td>-0.077523</td>\n",
       "      <td>0.303725</td>\n",
       "      <td>-0.121455</td>\n",
       "      <td>-0.120914</td>\n",
       "      <td>0.270511</td>\n",
       "      <td>0.226649</td>\n",
       "      <td>0.128650</td>\n",
       "      <td>-0.064698</td>\n",
       "      <td>0.088564</td>\n",
       "      <td>-0.136231</td>\n",
       "      <td>0.133351</td>\n",
       "      <td>0.053284</td>\n",
       "      <td>0.015309</td>\n",
       "      <td>0.059807</td>\n",
       "      <td>-0.302682</td>\n",
       "      <td>0.102252</td>\n",
       "      <td>-0.299771</td>\n",
       "      <td>-0.048789</td>\n",
       "      <td>0.057047</td>\n",
       "      <td>-0.176973</td>\n",
       "      <td>0.019946</td>\n",
       "      <td>0.217371</td>\n",
       "      <td>-0.115397</td>\n",
       "      <td>-0.066101</td>\n",
       "      <td>-0.234748</td>\n",
       "      <td>-0.114943</td>\n",
       "      <td>-0.057049</td>\n",
       "      <td>0.020394</td>\n",
       "      <td>0.136016</td>\n",
       "      <td>-0.115080</td>\n",
       "      <td>0.374386</td>\n",
       "      <td>-0.047619</td>\n",
       "      <td>0.232728</td>\n",
       "      <td>-0.275760</td>\n",
       "      <td>0.125658</td>\n",
       "      <td>0.121551</td>\n",
       "      <td>-0.096775</td>\n",
       "      <td>0.438111</td>\n",
       "      <td>-0.008546</td>\n",
       "      <td>0.041092</td>\n",
       "      <td>-0.246069</td>\n",
       "      <td>-0.079388</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.205297</td>\n",
       "      <td>-0.098522</td>\n",
       "      <td>0.264739</td>\n",
       "      <td>-0.081282</td>\n",
       "      <td>-0.050812</td>\n",
       "      <td>0.082191</td>\n",
       "      <td>-0.028498</td>\n",
       "      <td>0.050510</td>\n",
       "      <td>0.336514</td>\n",
       "      <td>0.177148</td>\n",
       "      <td>-0.013568</td>\n",
       "      <td>0.084151</td>\n",
       "      <td>0.021187</td>\n",
       "      <td>0.111406</td>\n",
       "      <td>-0.017754</td>\n",
       "      <td>0.079834</td>\n",
       "      <td>-0.163347</td>\n",
       "      <td>0.275612</td>\n",
       "      <td>-0.110479</td>\n",
       "      <td>0.065496</td>\n",
       "      <td>-0.254530</td>\n",
       "      <td>-0.048219</td>\n",
       "      <td>-0.093828</td>\n",
       "      <td>-0.146886</td>\n",
       "      <td>0.260245</td>\n",
       "      <td>0.013238</td>\n",
       "      <td>0.150387</td>\n",
       "      <td>0.049474</td>\n",
       "      <td>0.015870</td>\n",
       "      <td>-0.028968</td>\n",
       "      <td>0.139070</td>\n",
       "      <td>0.022450</td>\n",
       "      <td>-0.107487</td>\n",
       "      <td>-0.163419</td>\n",
       "      <td>-0.199246</td>\n",
       "      <td>-0.023974</td>\n",
       "      <td>0.058917</td>\n",
       "      <td>-0.193746</td>\n",
       "      <td>-0.017877</td>\n",
       "      <td>0.018693</td>\n",
       "      <td>-0.103422</td>\n",
       "      <td>-0.037057</td>\n",
       "      <td>0.177018</td>\n",
       "      <td>-0.212298</td>\n",
       "      <td>0.103260</td>\n",
       "      <td>-0.132177</td>\n",
       "      <td>0.142974</td>\n",
       "      <td>0.046403</td>\n",
       "      <td>-0.212879</td>\n",
       "      <td>0.024435</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>20</th>\n",
       "      <td>0.077037</td>\n",
       "      <td>-0.183716</td>\n",
       "      <td>-0.078878</td>\n",
       "      <td>0.221005</td>\n",
       "      <td>-0.225741</td>\n",
       "      <td>0.140500</td>\n",
       "      <td>-0.126052</td>\n",
       "      <td>0.241651</td>\n",
       "      <td>-0.077915</td>\n",
       "      <td>0.311869</td>\n",
       "      <td>-0.202382</td>\n",
       "      <td>-0.063032</td>\n",
       "      <td>0.156356</td>\n",
       "      <td>0.174272</td>\n",
       "      <td>0.144820</td>\n",
       "      <td>-0.106638</td>\n",
       "      <td>-0.005458</td>\n",
       "      <td>-0.191305</td>\n",
       "      <td>0.125788</td>\n",
       "      <td>-0.021658</td>\n",
       "      <td>-0.020402</td>\n",
       "      <td>-0.003678</td>\n",
       "      <td>-0.434763</td>\n",
       "      <td>0.111055</td>\n",
       "      <td>-0.277104</td>\n",
       "      <td>0.043994</td>\n",
       "      <td>0.101196</td>\n",
       "      <td>-0.202132</td>\n",
       "      <td>0.032809</td>\n",
       "      <td>0.232892</td>\n",
       "      <td>-0.150309</td>\n",
       "      <td>-0.022421</td>\n",
       "      <td>-0.274582</td>\n",
       "      <td>-0.034008</td>\n",
       "      <td>-0.022457</td>\n",
       "      <td>-0.033592</td>\n",
       "      <td>0.153044</td>\n",
       "      <td>0.036082</td>\n",
       "      <td>0.343732</td>\n",
       "      <td>-0.001198</td>\n",
       "      <td>0.192430</td>\n",
       "      <td>-0.248471</td>\n",
       "      <td>0.055220</td>\n",
       "      <td>0.161393</td>\n",
       "      <td>-0.069308</td>\n",
       "      <td>0.347031</td>\n",
       "      <td>-0.037571</td>\n",
       "      <td>0.066892</td>\n",
       "      <td>-0.243974</td>\n",
       "      <td>-0.085056</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.222701</td>\n",
       "      <td>-0.154216</td>\n",
       "      <td>0.257692</td>\n",
       "      <td>-0.133002</td>\n",
       "      <td>-0.049217</td>\n",
       "      <td>0.075391</td>\n",
       "      <td>-0.031818</td>\n",
       "      <td>0.087998</td>\n",
       "      <td>0.252650</td>\n",
       "      <td>0.162219</td>\n",
       "      <td>-0.009866</td>\n",
       "      <td>-0.087733</td>\n",
       "      <td>0.030578</td>\n",
       "      <td>0.193978</td>\n",
       "      <td>0.020966</td>\n",
       "      <td>0.013938</td>\n",
       "      <td>-0.201623</td>\n",
       "      <td>0.253537</td>\n",
       "      <td>-0.093881</td>\n",
       "      <td>0.021909</td>\n",
       "      <td>-0.252057</td>\n",
       "      <td>0.046438</td>\n",
       "      <td>-0.060296</td>\n",
       "      <td>-0.184460</td>\n",
       "      <td>0.267573</td>\n",
       "      <td>0.048974</td>\n",
       "      <td>0.193423</td>\n",
       "      <td>0.022759</td>\n",
       "      <td>0.122250</td>\n",
       "      <td>0.010786</td>\n",
       "      <td>0.119556</td>\n",
       "      <td>0.065383</td>\n",
       "      <td>-0.166989</td>\n",
       "      <td>-0.067826</td>\n",
       "      <td>-0.292029</td>\n",
       "      <td>-0.053049</td>\n",
       "      <td>0.035966</td>\n",
       "      <td>-0.203912</td>\n",
       "      <td>-0.005891</td>\n",
       "      <td>-0.003561</td>\n",
       "      <td>-0.085347</td>\n",
       "      <td>-0.121340</td>\n",
       "      <td>0.097155</td>\n",
       "      <td>-0.235379</td>\n",
       "      <td>0.083818</td>\n",
       "      <td>-0.100071</td>\n",
       "      <td>0.212479</td>\n",
       "      <td>0.091212</td>\n",
       "      <td>-0.221482</td>\n",
       "      <td>0.040179</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21</th>\n",
       "      <td>0.108381</td>\n",
       "      <td>-0.081589</td>\n",
       "      <td>-0.055114</td>\n",
       "      <td>0.192622</td>\n",
       "      <td>-0.184780</td>\n",
       "      <td>0.147259</td>\n",
       "      <td>-0.164205</td>\n",
       "      <td>0.174979</td>\n",
       "      <td>-0.042993</td>\n",
       "      <td>0.263492</td>\n",
       "      <td>-0.181490</td>\n",
       "      <td>-0.041247</td>\n",
       "      <td>0.159774</td>\n",
       "      <td>0.206809</td>\n",
       "      <td>0.205405</td>\n",
       "      <td>-0.142261</td>\n",
       "      <td>0.052151</td>\n",
       "      <td>-0.087046</td>\n",
       "      <td>0.066039</td>\n",
       "      <td>-0.028631</td>\n",
       "      <td>-0.011960</td>\n",
       "      <td>0.096913</td>\n",
       "      <td>-0.170000</td>\n",
       "      <td>0.058858</td>\n",
       "      <td>-0.286215</td>\n",
       "      <td>-0.002488</td>\n",
       "      <td>0.124444</td>\n",
       "      <td>-0.101212</td>\n",
       "      <td>0.004596</td>\n",
       "      <td>0.153619</td>\n",
       "      <td>-0.182718</td>\n",
       "      <td>-0.045681</td>\n",
       "      <td>-0.253282</td>\n",
       "      <td>-0.074058</td>\n",
       "      <td>-0.062720</td>\n",
       "      <td>0.048979</td>\n",
       "      <td>0.152726</td>\n",
       "      <td>-0.119026</td>\n",
       "      <td>0.281551</td>\n",
       "      <td>-0.055195</td>\n",
       "      <td>0.120447</td>\n",
       "      <td>-0.282217</td>\n",
       "      <td>0.048652</td>\n",
       "      <td>0.057211</td>\n",
       "      <td>-0.154303</td>\n",
       "      <td>0.347232</td>\n",
       "      <td>0.086475</td>\n",
       "      <td>0.049577</td>\n",
       "      <td>-0.191751</td>\n",
       "      <td>0.011338</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.318494</td>\n",
       "      <td>-0.189158</td>\n",
       "      <td>0.287165</td>\n",
       "      <td>-0.004630</td>\n",
       "      <td>-0.054570</td>\n",
       "      <td>0.085135</td>\n",
       "      <td>0.039934</td>\n",
       "      <td>0.041021</td>\n",
       "      <td>0.294397</td>\n",
       "      <td>0.172836</td>\n",
       "      <td>-0.057209</td>\n",
       "      <td>0.060619</td>\n",
       "      <td>0.017376</td>\n",
       "      <td>0.198594</td>\n",
       "      <td>0.076907</td>\n",
       "      <td>0.027844</td>\n",
       "      <td>-0.112461</td>\n",
       "      <td>0.226109</td>\n",
       "      <td>-0.121052</td>\n",
       "      <td>-0.001466</td>\n",
       "      <td>-0.291060</td>\n",
       "      <td>-0.112156</td>\n",
       "      <td>-0.067445</td>\n",
       "      <td>-0.117881</td>\n",
       "      <td>0.263439</td>\n",
       "      <td>0.060937</td>\n",
       "      <td>0.276333</td>\n",
       "      <td>0.031411</td>\n",
       "      <td>-0.014443</td>\n",
       "      <td>-0.006502</td>\n",
       "      <td>0.155565</td>\n",
       "      <td>0.098385</td>\n",
       "      <td>-0.105067</td>\n",
       "      <td>-0.102630</td>\n",
       "      <td>-0.113241</td>\n",
       "      <td>-0.093056</td>\n",
       "      <td>0.013762</td>\n",
       "      <td>-0.126994</td>\n",
       "      <td>0.028502</td>\n",
       "      <td>0.037380</td>\n",
       "      <td>-0.172519</td>\n",
       "      <td>-0.064627</td>\n",
       "      <td>0.160005</td>\n",
       "      <td>-0.093198</td>\n",
       "      <td>0.069294</td>\n",
       "      <td>-0.156810</td>\n",
       "      <td>0.056858</td>\n",
       "      <td>-0.029199</td>\n",
       "      <td>-0.288081</td>\n",
       "      <td>-0.004645</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>22</th>\n",
       "      <td>0.068633</td>\n",
       "      <td>-0.116530</td>\n",
       "      <td>-0.122826</td>\n",
       "      <td>0.191410</td>\n",
       "      <td>-0.212725</td>\n",
       "      <td>0.116594</td>\n",
       "      <td>-0.130537</td>\n",
       "      <td>0.214973</td>\n",
       "      <td>-0.053687</td>\n",
       "      <td>0.219447</td>\n",
       "      <td>-0.176421</td>\n",
       "      <td>-0.074450</td>\n",
       "      <td>0.145990</td>\n",
       "      <td>0.239703</td>\n",
       "      <td>0.201505</td>\n",
       "      <td>-0.117848</td>\n",
       "      <td>0.076289</td>\n",
       "      <td>-0.038788</td>\n",
       "      <td>0.095666</td>\n",
       "      <td>0.022654</td>\n",
       "      <td>0.041330</td>\n",
       "      <td>0.118158</td>\n",
       "      <td>-0.206337</td>\n",
       "      <td>0.114029</td>\n",
       "      <td>-0.311457</td>\n",
       "      <td>-0.054921</td>\n",
       "      <td>0.083903</td>\n",
       "      <td>-0.067038</td>\n",
       "      <td>0.007552</td>\n",
       "      <td>0.072820</td>\n",
       "      <td>-0.170625</td>\n",
       "      <td>-0.048674</td>\n",
       "      <td>-0.325056</td>\n",
       "      <td>-0.076302</td>\n",
       "      <td>-0.081698</td>\n",
       "      <td>0.083015</td>\n",
       "      <td>0.178071</td>\n",
       "      <td>-0.111612</td>\n",
       "      <td>0.327810</td>\n",
       "      <td>-0.116179</td>\n",
       "      <td>0.131110</td>\n",
       "      <td>-0.242640</td>\n",
       "      <td>0.054334</td>\n",
       "      <td>0.119811</td>\n",
       "      <td>-0.150140</td>\n",
       "      <td>0.337917</td>\n",
       "      <td>0.011412</td>\n",
       "      <td>0.126462</td>\n",
       "      <td>-0.239658</td>\n",
       "      <td>0.003721</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.283057</td>\n",
       "      <td>-0.145005</td>\n",
       "      <td>0.278447</td>\n",
       "      <td>-0.123844</td>\n",
       "      <td>0.008364</td>\n",
       "      <td>0.088861</td>\n",
       "      <td>0.051534</td>\n",
       "      <td>0.076604</td>\n",
       "      <td>0.264076</td>\n",
       "      <td>0.173068</td>\n",
       "      <td>-0.072581</td>\n",
       "      <td>0.033263</td>\n",
       "      <td>0.014161</td>\n",
       "      <td>0.140409</td>\n",
       "      <td>0.123890</td>\n",
       "      <td>-0.017939</td>\n",
       "      <td>-0.103966</td>\n",
       "      <td>0.192167</td>\n",
       "      <td>-0.108350</td>\n",
       "      <td>-0.036111</td>\n",
       "      <td>-0.233682</td>\n",
       "      <td>-0.099015</td>\n",
       "      <td>-0.111950</td>\n",
       "      <td>-0.134761</td>\n",
       "      <td>0.325938</td>\n",
       "      <td>0.077487</td>\n",
       "      <td>0.213453</td>\n",
       "      <td>-0.052382</td>\n",
       "      <td>0.003257</td>\n",
       "      <td>-0.022888</td>\n",
       "      <td>0.190573</td>\n",
       "      <td>0.170840</td>\n",
       "      <td>-0.078206</td>\n",
       "      <td>-0.096388</td>\n",
       "      <td>-0.160876</td>\n",
       "      <td>-0.049031</td>\n",
       "      <td>0.005124</td>\n",
       "      <td>-0.232078</td>\n",
       "      <td>0.063473</td>\n",
       "      <td>0.027322</td>\n",
       "      <td>-0.185626</td>\n",
       "      <td>-0.080397</td>\n",
       "      <td>0.160207</td>\n",
       "      <td>-0.123469</td>\n",
       "      <td>0.079884</td>\n",
       "      <td>-0.181897</td>\n",
       "      <td>0.015341</td>\n",
       "      <td>-0.022915</td>\n",
       "      <td>-0.252235</td>\n",
       "      <td>-0.001133</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23</th>\n",
       "      <td>0.145713</td>\n",
       "      <td>-0.101404</td>\n",
       "      <td>-0.125913</td>\n",
       "      <td>0.222237</td>\n",
       "      <td>-0.201406</td>\n",
       "      <td>0.128724</td>\n",
       "      <td>-0.109298</td>\n",
       "      <td>0.216365</td>\n",
       "      <td>-0.066860</td>\n",
       "      <td>0.325413</td>\n",
       "      <td>-0.193386</td>\n",
       "      <td>-0.072068</td>\n",
       "      <td>0.185118</td>\n",
       "      <td>0.083937</td>\n",
       "      <td>0.128757</td>\n",
       "      <td>-0.176697</td>\n",
       "      <td>-0.029923</td>\n",
       "      <td>-0.189268</td>\n",
       "      <td>0.148491</td>\n",
       "      <td>-0.037742</td>\n",
       "      <td>0.112322</td>\n",
       "      <td>0.044258</td>\n",
       "      <td>-0.361242</td>\n",
       "      <td>0.084291</td>\n",
       "      <td>-0.300882</td>\n",
       "      <td>0.035149</td>\n",
       "      <td>0.060617</td>\n",
       "      <td>-0.197932</td>\n",
       "      <td>0.007936</td>\n",
       "      <td>0.218270</td>\n",
       "      <td>-0.171300</td>\n",
       "      <td>-0.061869</td>\n",
       "      <td>-0.253635</td>\n",
       "      <td>-0.072974</td>\n",
       "      <td>-0.131612</td>\n",
       "      <td>-0.052320</td>\n",
       "      <td>0.183731</td>\n",
       "      <td>-0.027726</td>\n",
       "      <td>0.351872</td>\n",
       "      <td>0.049659</td>\n",
       "      <td>0.208683</td>\n",
       "      <td>-0.234929</td>\n",
       "      <td>0.062586</td>\n",
       "      <td>0.103289</td>\n",
       "      <td>-0.038530</td>\n",
       "      <td>0.306830</td>\n",
       "      <td>-0.000457</td>\n",
       "      <td>0.041841</td>\n",
       "      <td>-0.160119</td>\n",
       "      <td>-0.156679</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.299804</td>\n",
       "      <td>-0.113300</td>\n",
       "      <td>0.287763</td>\n",
       "      <td>-0.073148</td>\n",
       "      <td>-0.099946</td>\n",
       "      <td>0.064919</td>\n",
       "      <td>-0.023141</td>\n",
       "      <td>0.126656</td>\n",
       "      <td>0.262134</td>\n",
       "      <td>0.202606</td>\n",
       "      <td>0.006136</td>\n",
       "      <td>-0.046622</td>\n",
       "      <td>-0.002979</td>\n",
       "      <td>0.229610</td>\n",
       "      <td>0.080771</td>\n",
       "      <td>0.069408</td>\n",
       "      <td>-0.204974</td>\n",
       "      <td>0.224885</td>\n",
       "      <td>-0.064545</td>\n",
       "      <td>-0.000130</td>\n",
       "      <td>-0.274943</td>\n",
       "      <td>-0.045236</td>\n",
       "      <td>-0.099797</td>\n",
       "      <td>-0.200392</td>\n",
       "      <td>0.279266</td>\n",
       "      <td>0.071460</td>\n",
       "      <td>0.204050</td>\n",
       "      <td>0.001359</td>\n",
       "      <td>0.034640</td>\n",
       "      <td>0.028149</td>\n",
       "      <td>0.054354</td>\n",
       "      <td>0.030405</td>\n",
       "      <td>-0.125908</td>\n",
       "      <td>-0.058175</td>\n",
       "      <td>-0.155791</td>\n",
       "      <td>-0.036760</td>\n",
       "      <td>-0.052245</td>\n",
       "      <td>-0.258229</td>\n",
       "      <td>-0.052590</td>\n",
       "      <td>0.037014</td>\n",
       "      <td>-0.106041</td>\n",
       "      <td>-0.102339</td>\n",
       "      <td>0.100616</td>\n",
       "      <td>-0.224136</td>\n",
       "      <td>0.038352</td>\n",
       "      <td>-0.140287</td>\n",
       "      <td>0.087144</td>\n",
       "      <td>0.055093</td>\n",
       "      <td>-0.235837</td>\n",
       "      <td>0.036125</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24</th>\n",
       "      <td>0.033266</td>\n",
       "      <td>-0.161788</td>\n",
       "      <td>-0.071069</td>\n",
       "      <td>0.208008</td>\n",
       "      <td>-0.216877</td>\n",
       "      <td>0.170222</td>\n",
       "      <td>-0.124472</td>\n",
       "      <td>0.224440</td>\n",
       "      <td>-0.081342</td>\n",
       "      <td>0.322718</td>\n",
       "      <td>-0.176819</td>\n",
       "      <td>-0.079520</td>\n",
       "      <td>0.233964</td>\n",
       "      <td>0.206922</td>\n",
       "      <td>0.140089</td>\n",
       "      <td>-0.129153</td>\n",
       "      <td>-0.044857</td>\n",
       "      <td>-0.087826</td>\n",
       "      <td>0.066613</td>\n",
       "      <td>0.000763</td>\n",
       "      <td>-0.015396</td>\n",
       "      <td>0.082149</td>\n",
       "      <td>-0.323721</td>\n",
       "      <td>0.112585</td>\n",
       "      <td>-0.288654</td>\n",
       "      <td>0.014755</td>\n",
       "      <td>0.051435</td>\n",
       "      <td>-0.115221</td>\n",
       "      <td>-0.010049</td>\n",
       "      <td>0.161967</td>\n",
       "      <td>-0.173949</td>\n",
       "      <td>-0.021588</td>\n",
       "      <td>-0.268219</td>\n",
       "      <td>-0.067375</td>\n",
       "      <td>-0.024115</td>\n",
       "      <td>-0.002154</td>\n",
       "      <td>0.217863</td>\n",
       "      <td>-0.076387</td>\n",
       "      <td>0.278421</td>\n",
       "      <td>-0.066007</td>\n",
       "      <td>0.148879</td>\n",
       "      <td>-0.276389</td>\n",
       "      <td>0.074848</td>\n",
       "      <td>0.101926</td>\n",
       "      <td>-0.080650</td>\n",
       "      <td>0.322797</td>\n",
       "      <td>0.021097</td>\n",
       "      <td>0.068251</td>\n",
       "      <td>-0.176109</td>\n",
       "      <td>-0.026915</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.357404</td>\n",
       "      <td>-0.266387</td>\n",
       "      <td>0.278025</td>\n",
       "      <td>-0.029581</td>\n",
       "      <td>-0.001778</td>\n",
       "      <td>0.114736</td>\n",
       "      <td>-0.011721</td>\n",
       "      <td>0.097755</td>\n",
       "      <td>0.296347</td>\n",
       "      <td>0.186095</td>\n",
       "      <td>-0.022225</td>\n",
       "      <td>0.011246</td>\n",
       "      <td>0.008808</td>\n",
       "      <td>0.178345</td>\n",
       "      <td>0.080846</td>\n",
       "      <td>0.003029</td>\n",
       "      <td>-0.165547</td>\n",
       "      <td>0.228465</td>\n",
       "      <td>-0.168007</td>\n",
       "      <td>0.023919</td>\n",
       "      <td>-0.261253</td>\n",
       "      <td>-0.073074</td>\n",
       "      <td>-0.094644</td>\n",
       "      <td>-0.094901</td>\n",
       "      <td>0.306892</td>\n",
       "      <td>-0.056014</td>\n",
       "      <td>0.285901</td>\n",
       "      <td>-0.038950</td>\n",
       "      <td>0.044506</td>\n",
       "      <td>-0.008231</td>\n",
       "      <td>0.141204</td>\n",
       "      <td>0.050306</td>\n",
       "      <td>-0.122646</td>\n",
       "      <td>-0.100723</td>\n",
       "      <td>-0.109429</td>\n",
       "      <td>-0.062236</td>\n",
       "      <td>0.027140</td>\n",
       "      <td>-0.168427</td>\n",
       "      <td>-0.006313</td>\n",
       "      <td>0.024699</td>\n",
       "      <td>-0.141803</td>\n",
       "      <td>-0.102491</td>\n",
       "      <td>0.113387</td>\n",
       "      <td>-0.192079</td>\n",
       "      <td>0.119675</td>\n",
       "      <td>-0.164787</td>\n",
       "      <td>0.086681</td>\n",
       "      <td>0.024787</td>\n",
       "      <td>-0.235165</td>\n",
       "      <td>0.074328</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>25</th>\n",
       "      <td>0.110078</td>\n",
       "      <td>-0.165039</td>\n",
       "      <td>-0.088430</td>\n",
       "      <td>0.200475</td>\n",
       "      <td>-0.237514</td>\n",
       "      <td>0.151888</td>\n",
       "      <td>-0.083922</td>\n",
       "      <td>0.174967</td>\n",
       "      <td>-0.082083</td>\n",
       "      <td>0.258345</td>\n",
       "      <td>-0.135890</td>\n",
       "      <td>-0.064309</td>\n",
       "      <td>0.204680</td>\n",
       "      <td>0.199883</td>\n",
       "      <td>0.137611</td>\n",
       "      <td>-0.115061</td>\n",
       "      <td>-0.024605</td>\n",
       "      <td>-0.042803</td>\n",
       "      <td>0.131858</td>\n",
       "      <td>-0.012668</td>\n",
       "      <td>0.051934</td>\n",
       "      <td>0.096876</td>\n",
       "      <td>-0.274776</td>\n",
       "      <td>0.122050</td>\n",
       "      <td>-0.254711</td>\n",
       "      <td>-0.004496</td>\n",
       "      <td>0.072682</td>\n",
       "      <td>-0.098179</td>\n",
       "      <td>0.042528</td>\n",
       "      <td>0.122180</td>\n",
       "      <td>-0.160181</td>\n",
       "      <td>0.003436</td>\n",
       "      <td>-0.335380</td>\n",
       "      <td>-0.053382</td>\n",
       "      <td>-0.080513</td>\n",
       "      <td>0.015533</td>\n",
       "      <td>0.202166</td>\n",
       "      <td>-0.130769</td>\n",
       "      <td>0.324284</td>\n",
       "      <td>-0.081831</td>\n",
       "      <td>0.124339</td>\n",
       "      <td>-0.228217</td>\n",
       "      <td>0.055875</td>\n",
       "      <td>0.129623</td>\n",
       "      <td>-0.116583</td>\n",
       "      <td>0.284579</td>\n",
       "      <td>0.004653</td>\n",
       "      <td>0.127671</td>\n",
       "      <td>-0.241101</td>\n",
       "      <td>-0.003893</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.322456</td>\n",
       "      <td>-0.224698</td>\n",
       "      <td>0.271277</td>\n",
       "      <td>-0.124126</td>\n",
       "      <td>0.020542</td>\n",
       "      <td>0.096496</td>\n",
       "      <td>-0.007113</td>\n",
       "      <td>0.102541</td>\n",
       "      <td>0.219152</td>\n",
       "      <td>0.159148</td>\n",
       "      <td>-0.056704</td>\n",
       "      <td>-0.033739</td>\n",
       "      <td>0.047068</td>\n",
       "      <td>0.218816</td>\n",
       "      <td>0.073444</td>\n",
       "      <td>-0.080709</td>\n",
       "      <td>-0.211578</td>\n",
       "      <td>0.246042</td>\n",
       "      <td>-0.169766</td>\n",
       "      <td>-0.024663</td>\n",
       "      <td>-0.247924</td>\n",
       "      <td>-0.077050</td>\n",
       "      <td>-0.024093</td>\n",
       "      <td>-0.124654</td>\n",
       "      <td>0.302890</td>\n",
       "      <td>0.046415</td>\n",
       "      <td>0.246667</td>\n",
       "      <td>-0.070088</td>\n",
       "      <td>0.030879</td>\n",
       "      <td>0.014932</td>\n",
       "      <td>0.175465</td>\n",
       "      <td>0.164267</td>\n",
       "      <td>-0.095272</td>\n",
       "      <td>-0.068908</td>\n",
       "      <td>-0.146437</td>\n",
       "      <td>-0.061429</td>\n",
       "      <td>0.016553</td>\n",
       "      <td>-0.266642</td>\n",
       "      <td>-0.021232</td>\n",
       "      <td>0.005664</td>\n",
       "      <td>-0.200571</td>\n",
       "      <td>-0.105977</td>\n",
       "      <td>0.141263</td>\n",
       "      <td>-0.163351</td>\n",
       "      <td>0.034896</td>\n",
       "      <td>-0.190815</td>\n",
       "      <td>0.058171</td>\n",
       "      <td>-0.014313</td>\n",
       "      <td>-0.282180</td>\n",
       "      <td>0.021420</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26</th>\n",
       "      <td>0.175475</td>\n",
       "      <td>-0.128516</td>\n",
       "      <td>-0.128148</td>\n",
       "      <td>0.216492</td>\n",
       "      <td>-0.247868</td>\n",
       "      <td>0.090050</td>\n",
       "      <td>-0.147215</td>\n",
       "      <td>0.259016</td>\n",
       "      <td>-0.110687</td>\n",
       "      <td>0.279462</td>\n",
       "      <td>-0.111973</td>\n",
       "      <td>-0.111929</td>\n",
       "      <td>0.227249</td>\n",
       "      <td>0.226590</td>\n",
       "      <td>0.184725</td>\n",
       "      <td>-0.101531</td>\n",
       "      <td>0.066842</td>\n",
       "      <td>-0.134927</td>\n",
       "      <td>0.044560</td>\n",
       "      <td>-0.009920</td>\n",
       "      <td>0.100811</td>\n",
       "      <td>0.094685</td>\n",
       "      <td>-0.172429</td>\n",
       "      <td>0.108198</td>\n",
       "      <td>-0.265909</td>\n",
       "      <td>-0.019480</td>\n",
       "      <td>0.111598</td>\n",
       "      <td>-0.092332</td>\n",
       "      <td>0.032621</td>\n",
       "      <td>0.191839</td>\n",
       "      <td>-0.139661</td>\n",
       "      <td>-0.048391</td>\n",
       "      <td>-0.281992</td>\n",
       "      <td>-0.063394</td>\n",
       "      <td>-0.061228</td>\n",
       "      <td>0.084730</td>\n",
       "      <td>0.170180</td>\n",
       "      <td>-0.112418</td>\n",
       "      <td>0.364602</td>\n",
       "      <td>-0.081842</td>\n",
       "      <td>0.214739</td>\n",
       "      <td>-0.326534</td>\n",
       "      <td>0.097163</td>\n",
       "      <td>0.089863</td>\n",
       "      <td>-0.101911</td>\n",
       "      <td>0.395987</td>\n",
       "      <td>0.027899</td>\n",
       "      <td>0.046090</td>\n",
       "      <td>-0.205421</td>\n",
       "      <td>-0.030896</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.265901</td>\n",
       "      <td>-0.153907</td>\n",
       "      <td>0.281870</td>\n",
       "      <td>0.009714</td>\n",
       "      <td>-0.043309</td>\n",
       "      <td>0.129538</td>\n",
       "      <td>-0.012523</td>\n",
       "      <td>0.020251</td>\n",
       "      <td>0.325380</td>\n",
       "      <td>0.216869</td>\n",
       "      <td>-0.020758</td>\n",
       "      <td>0.110658</td>\n",
       "      <td>0.009731</td>\n",
       "      <td>0.155158</td>\n",
       "      <td>0.102541</td>\n",
       "      <td>-0.026054</td>\n",
       "      <td>-0.120567</td>\n",
       "      <td>0.240298</td>\n",
       "      <td>-0.166900</td>\n",
       "      <td>-0.023774</td>\n",
       "      <td>-0.283795</td>\n",
       "      <td>-0.058664</td>\n",
       "      <td>-0.065946</td>\n",
       "      <td>-0.165836</td>\n",
       "      <td>0.257677</td>\n",
       "      <td>0.024638</td>\n",
       "      <td>0.157943</td>\n",
       "      <td>0.014934</td>\n",
       "      <td>-0.014605</td>\n",
       "      <td>0.052121</td>\n",
       "      <td>0.136302</td>\n",
       "      <td>0.101943</td>\n",
       "      <td>-0.091247</td>\n",
       "      <td>-0.133936</td>\n",
       "      <td>-0.133265</td>\n",
       "      <td>-0.095080</td>\n",
       "      <td>0.008851</td>\n",
       "      <td>-0.268255</td>\n",
       "      <td>0.006170</td>\n",
       "      <td>0.003974</td>\n",
       "      <td>-0.088212</td>\n",
       "      <td>-0.061540</td>\n",
       "      <td>0.139239</td>\n",
       "      <td>-0.128385</td>\n",
       "      <td>0.114811</td>\n",
       "      <td>-0.187927</td>\n",
       "      <td>0.053327</td>\n",
       "      <td>-0.027933</td>\n",
       "      <td>-0.260661</td>\n",
       "      <td>0.081768</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>27</th>\n",
       "      <td>0.068280</td>\n",
       "      <td>-0.143120</td>\n",
       "      <td>-0.111334</td>\n",
       "      <td>0.221054</td>\n",
       "      <td>-0.246314</td>\n",
       "      <td>0.107133</td>\n",
       "      <td>-0.151142</td>\n",
       "      <td>0.249594</td>\n",
       "      <td>-0.104961</td>\n",
       "      <td>0.236302</td>\n",
       "      <td>-0.203484</td>\n",
       "      <td>-0.093636</td>\n",
       "      <td>0.142345</td>\n",
       "      <td>0.250931</td>\n",
       "      <td>0.204709</td>\n",
       "      <td>-0.116570</td>\n",
       "      <td>0.015593</td>\n",
       "      <td>-0.131217</td>\n",
       "      <td>0.029938</td>\n",
       "      <td>0.048693</td>\n",
       "      <td>0.049763</td>\n",
       "      <td>0.095102</td>\n",
       "      <td>-0.245136</td>\n",
       "      <td>0.086482</td>\n",
       "      <td>-0.296598</td>\n",
       "      <td>-0.051461</td>\n",
       "      <td>0.080661</td>\n",
       "      <td>-0.075639</td>\n",
       "      <td>-0.044463</td>\n",
       "      <td>0.135011</td>\n",
       "      <td>-0.146749</td>\n",
       "      <td>-0.042630</td>\n",
       "      <td>-0.259667</td>\n",
       "      <td>-0.067494</td>\n",
       "      <td>-0.075882</td>\n",
       "      <td>0.062792</td>\n",
       "      <td>0.160358</td>\n",
       "      <td>-0.120987</td>\n",
       "      <td>0.337587</td>\n",
       "      <td>-0.099148</td>\n",
       "      <td>0.148384</td>\n",
       "      <td>-0.257090</td>\n",
       "      <td>0.050791</td>\n",
       "      <td>0.135780</td>\n",
       "      <td>-0.138661</td>\n",
       "      <td>0.363026</td>\n",
       "      <td>0.077660</td>\n",
       "      <td>0.133712</td>\n",
       "      <td>-0.237007</td>\n",
       "      <td>0.030092</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.290918</td>\n",
       "      <td>-0.207489</td>\n",
       "      <td>0.310473</td>\n",
       "      <td>-0.024739</td>\n",
       "      <td>-0.105899</td>\n",
       "      <td>0.141126</td>\n",
       "      <td>0.038993</td>\n",
       "      <td>0.085714</td>\n",
       "      <td>0.316383</td>\n",
       "      <td>0.125881</td>\n",
       "      <td>-0.037108</td>\n",
       "      <td>0.066552</td>\n",
       "      <td>0.028385</td>\n",
       "      <td>0.121593</td>\n",
       "      <td>0.030406</td>\n",
       "      <td>-0.021375</td>\n",
       "      <td>-0.106647</td>\n",
       "      <td>0.227662</td>\n",
       "      <td>-0.102719</td>\n",
       "      <td>0.001835</td>\n",
       "      <td>-0.261946</td>\n",
       "      <td>-0.044614</td>\n",
       "      <td>-0.092806</td>\n",
       "      <td>-0.158293</td>\n",
       "      <td>0.285538</td>\n",
       "      <td>-0.002938</td>\n",
       "      <td>0.228986</td>\n",
       "      <td>-0.052771</td>\n",
       "      <td>-0.004690</td>\n",
       "      <td>-0.038297</td>\n",
       "      <td>0.169452</td>\n",
       "      <td>0.107938</td>\n",
       "      <td>-0.090290</td>\n",
       "      <td>-0.126887</td>\n",
       "      <td>-0.163463</td>\n",
       "      <td>-0.074908</td>\n",
       "      <td>0.042002</td>\n",
       "      <td>-0.230969</td>\n",
       "      <td>0.056041</td>\n",
       "      <td>0.053460</td>\n",
       "      <td>-0.119225</td>\n",
       "      <td>-0.062688</td>\n",
       "      <td>0.147356</td>\n",
       "      <td>-0.124680</td>\n",
       "      <td>0.094467</td>\n",
       "      <td>-0.194348</td>\n",
       "      <td>0.053529</td>\n",
       "      <td>-0.043625</td>\n",
       "      <td>-0.254566</td>\n",
       "      <td>0.068075</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>28</th>\n",
       "      <td>0.116597</td>\n",
       "      <td>-0.049208</td>\n",
       "      <td>-0.085304</td>\n",
       "      <td>0.274759</td>\n",
       "      <td>-0.238337</td>\n",
       "      <td>0.104141</td>\n",
       "      <td>-0.151078</td>\n",
       "      <td>0.162720</td>\n",
       "      <td>-0.016946</td>\n",
       "      <td>0.270031</td>\n",
       "      <td>-0.128106</td>\n",
       "      <td>-0.139958</td>\n",
       "      <td>0.234293</td>\n",
       "      <td>0.235587</td>\n",
       "      <td>0.151791</td>\n",
       "      <td>-0.052878</td>\n",
       "      <td>0.044726</td>\n",
       "      <td>-0.132298</td>\n",
       "      <td>0.079090</td>\n",
       "      <td>0.006276</td>\n",
       "      <td>-0.024541</td>\n",
       "      <td>0.069220</td>\n",
       "      <td>-0.275774</td>\n",
       "      <td>0.100916</td>\n",
       "      <td>-0.264087</td>\n",
       "      <td>-0.008081</td>\n",
       "      <td>0.062462</td>\n",
       "      <td>-0.180195</td>\n",
       "      <td>0.012465</td>\n",
       "      <td>0.281192</td>\n",
       "      <td>-0.088081</td>\n",
       "      <td>-0.105013</td>\n",
       "      <td>-0.264657</td>\n",
       "      <td>-0.103804</td>\n",
       "      <td>-0.086743</td>\n",
       "      <td>0.024948</td>\n",
       "      <td>0.116364</td>\n",
       "      <td>-0.077394</td>\n",
       "      <td>0.362752</td>\n",
       "      <td>-0.025464</td>\n",
       "      <td>0.203469</td>\n",
       "      <td>-0.234783</td>\n",
       "      <td>0.085146</td>\n",
       "      <td>0.137293</td>\n",
       "      <td>-0.119782</td>\n",
       "      <td>0.362535</td>\n",
       "      <td>-0.005930</td>\n",
       "      <td>0.062721</td>\n",
       "      <td>-0.217778</td>\n",
       "      <td>-0.074803</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.307709</td>\n",
       "      <td>-0.193954</td>\n",
       "      <td>0.293728</td>\n",
       "      <td>-0.024604</td>\n",
       "      <td>-0.036003</td>\n",
       "      <td>0.070311</td>\n",
       "      <td>-0.022755</td>\n",
       "      <td>0.119635</td>\n",
       "      <td>0.308824</td>\n",
       "      <td>0.147953</td>\n",
       "      <td>0.021667</td>\n",
       "      <td>0.062966</td>\n",
       "      <td>-0.012604</td>\n",
       "      <td>0.199840</td>\n",
       "      <td>0.044222</td>\n",
       "      <td>0.067166</td>\n",
       "      <td>-0.169962</td>\n",
       "      <td>0.307528</td>\n",
       "      <td>-0.042408</td>\n",
       "      <td>0.031395</td>\n",
       "      <td>-0.310558</td>\n",
       "      <td>-0.078147</td>\n",
       "      <td>-0.178513</td>\n",
       "      <td>-0.140652</td>\n",
       "      <td>0.296021</td>\n",
       "      <td>0.042895</td>\n",
       "      <td>0.207683</td>\n",
       "      <td>-0.006534</td>\n",
       "      <td>0.019877</td>\n",
       "      <td>-0.000897</td>\n",
       "      <td>0.078116</td>\n",
       "      <td>0.056427</td>\n",
       "      <td>-0.114573</td>\n",
       "      <td>-0.114518</td>\n",
       "      <td>-0.188509</td>\n",
       "      <td>0.017538</td>\n",
       "      <td>0.061767</td>\n",
       "      <td>-0.222352</td>\n",
       "      <td>0.070590</td>\n",
       "      <td>0.009440</td>\n",
       "      <td>-0.162331</td>\n",
       "      <td>-0.014711</td>\n",
       "      <td>0.134727</td>\n",
       "      <td>-0.169922</td>\n",
       "      <td>0.105697</td>\n",
       "      <td>-0.160824</td>\n",
       "      <td>0.122069</td>\n",
       "      <td>-0.006020</td>\n",
       "      <td>-0.214408</td>\n",
       "      <td>0.029898</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>29</th>\n",
       "      <td>0.109027</td>\n",
       "      <td>-0.166159</td>\n",
       "      <td>-0.122024</td>\n",
       "      <td>0.257628</td>\n",
       "      <td>-0.247994</td>\n",
       "      <td>0.102348</td>\n",
       "      <td>-0.130679</td>\n",
       "      <td>0.169716</td>\n",
       "      <td>-0.066886</td>\n",
       "      <td>0.307891</td>\n",
       "      <td>-0.146968</td>\n",
       "      <td>-0.067540</td>\n",
       "      <td>0.242495</td>\n",
       "      <td>0.188618</td>\n",
       "      <td>0.146738</td>\n",
       "      <td>-0.110729</td>\n",
       "      <td>0.108971</td>\n",
       "      <td>-0.173095</td>\n",
       "      <td>0.126173</td>\n",
       "      <td>-0.006610</td>\n",
       "      <td>0.055242</td>\n",
       "      <td>0.002200</td>\n",
       "      <td>-0.350678</td>\n",
       "      <td>0.065735</td>\n",
       "      <td>-0.253242</td>\n",
       "      <td>0.039975</td>\n",
       "      <td>0.097954</td>\n",
       "      <td>-0.187782</td>\n",
       "      <td>0.065891</td>\n",
       "      <td>0.172706</td>\n",
       "      <td>-0.101303</td>\n",
       "      <td>-0.029959</td>\n",
       "      <td>-0.207586</td>\n",
       "      <td>-0.108257</td>\n",
       "      <td>-0.059105</td>\n",
       "      <td>-0.091941</td>\n",
       "      <td>0.196308</td>\n",
       "      <td>-0.085058</td>\n",
       "      <td>0.329245</td>\n",
       "      <td>-0.045768</td>\n",
       "      <td>0.260565</td>\n",
       "      <td>-0.269938</td>\n",
       "      <td>0.069752</td>\n",
       "      <td>0.080240</td>\n",
       "      <td>-0.044075</td>\n",
       "      <td>0.410438</td>\n",
       "      <td>0.004668</td>\n",
       "      <td>0.069785</td>\n",
       "      <td>-0.148011</td>\n",
       "      <td>-0.115484</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.268022</td>\n",
       "      <td>-0.102675</td>\n",
       "      <td>0.214879</td>\n",
       "      <td>-0.037770</td>\n",
       "      <td>-0.081948</td>\n",
       "      <td>0.084980</td>\n",
       "      <td>-0.043232</td>\n",
       "      <td>0.025902</td>\n",
       "      <td>0.323834</td>\n",
       "      <td>0.185922</td>\n",
       "      <td>-0.029285</td>\n",
       "      <td>0.048238</td>\n",
       "      <td>0.032020</td>\n",
       "      <td>0.121501</td>\n",
       "      <td>-0.010212</td>\n",
       "      <td>0.079603</td>\n",
       "      <td>-0.220643</td>\n",
       "      <td>0.298374</td>\n",
       "      <td>-0.100142</td>\n",
       "      <td>0.056994</td>\n",
       "      <td>-0.220374</td>\n",
       "      <td>-0.007496</td>\n",
       "      <td>0.001573</td>\n",
       "      <td>-0.145973</td>\n",
       "      <td>0.228874</td>\n",
       "      <td>0.060474</td>\n",
       "      <td>0.143827</td>\n",
       "      <td>0.060814</td>\n",
       "      <td>0.061233</td>\n",
       "      <td>-0.002911</td>\n",
       "      <td>0.147292</td>\n",
       "      <td>0.020246</td>\n",
       "      <td>-0.095858</td>\n",
       "      <td>-0.144134</td>\n",
       "      <td>-0.247790</td>\n",
       "      <td>-0.015183</td>\n",
       "      <td>0.000040</td>\n",
       "      <td>-0.142985</td>\n",
       "      <td>-0.066704</td>\n",
       "      <td>-0.032258</td>\n",
       "      <td>-0.120343</td>\n",
       "      <td>-0.088690</td>\n",
       "      <td>0.098280</td>\n",
       "      <td>-0.251099</td>\n",
       "      <td>0.097493</td>\n",
       "      <td>-0.109451</td>\n",
       "      <td>0.170236</td>\n",
       "      <td>0.067383</td>\n",
       "      <td>-0.160730</td>\n",
       "      <td>-0.026558</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>30</th>\n",
       "      <td>0.094652</td>\n",
       "      <td>-0.095609</td>\n",
       "      <td>-0.097690</td>\n",
       "      <td>0.187054</td>\n",
       "      <td>-0.244375</td>\n",
       "      <td>0.148235</td>\n",
       "      <td>-0.148863</td>\n",
       "      <td>0.265033</td>\n",
       "      <td>-0.045692</td>\n",
       "      <td>0.277706</td>\n",
       "      <td>-0.136480</td>\n",
       "      <td>-0.111525</td>\n",
       "      <td>0.332094</td>\n",
       "      <td>0.189192</td>\n",
       "      <td>0.137897</td>\n",
       "      <td>-0.105132</td>\n",
       "      <td>0.092612</td>\n",
       "      <td>-0.193866</td>\n",
       "      <td>0.120582</td>\n",
       "      <td>0.028512</td>\n",
       "      <td>0.022100</td>\n",
       "      <td>0.066255</td>\n",
       "      <td>-0.387258</td>\n",
       "      <td>0.183049</td>\n",
       "      <td>-0.226823</td>\n",
       "      <td>-0.043580</td>\n",
       "      <td>0.019720</td>\n",
       "      <td>-0.135307</td>\n",
       "      <td>-0.026478</td>\n",
       "      <td>0.303840</td>\n",
       "      <td>-0.069351</td>\n",
       "      <td>-0.097274</td>\n",
       "      <td>-0.259993</td>\n",
       "      <td>-0.088982</td>\n",
       "      <td>-0.041849</td>\n",
       "      <td>0.020321</td>\n",
       "      <td>0.185650</td>\n",
       "      <td>-0.051020</td>\n",
       "      <td>0.394498</td>\n",
       "      <td>0.032651</td>\n",
       "      <td>0.169578</td>\n",
       "      <td>-0.279043</td>\n",
       "      <td>0.114414</td>\n",
       "      <td>0.140740</td>\n",
       "      <td>-0.118944</td>\n",
       "      <td>0.402227</td>\n",
       "      <td>-0.008603</td>\n",
       "      <td>0.100816</td>\n",
       "      <td>-0.202231</td>\n",
       "      <td>-0.107559</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.283304</td>\n",
       "      <td>-0.177984</td>\n",
       "      <td>0.317129</td>\n",
       "      <td>-0.065851</td>\n",
       "      <td>-0.084334</td>\n",
       "      <td>0.033224</td>\n",
       "      <td>0.015540</td>\n",
       "      <td>0.056321</td>\n",
       "      <td>0.286532</td>\n",
       "      <td>0.181740</td>\n",
       "      <td>0.003825</td>\n",
       "      <td>0.022871</td>\n",
       "      <td>0.047883</td>\n",
       "      <td>0.201234</td>\n",
       "      <td>0.050664</td>\n",
       "      <td>0.030532</td>\n",
       "      <td>-0.176618</td>\n",
       "      <td>0.235617</td>\n",
       "      <td>-0.078661</td>\n",
       "      <td>-0.010192</td>\n",
       "      <td>-0.291951</td>\n",
       "      <td>-0.059978</td>\n",
       "      <td>-0.174797</td>\n",
       "      <td>-0.164801</td>\n",
       "      <td>0.332326</td>\n",
       "      <td>0.047596</td>\n",
       "      <td>0.159567</td>\n",
       "      <td>-0.056273</td>\n",
       "      <td>0.049838</td>\n",
       "      <td>-0.013237</td>\n",
       "      <td>0.082750</td>\n",
       "      <td>0.015319</td>\n",
       "      <td>-0.127518</td>\n",
       "      <td>-0.116965</td>\n",
       "      <td>-0.200193</td>\n",
       "      <td>-0.045112</td>\n",
       "      <td>0.019443</td>\n",
       "      <td>-0.261863</td>\n",
       "      <td>0.005851</td>\n",
       "      <td>0.001197</td>\n",
       "      <td>-0.142963</td>\n",
       "      <td>-0.040226</td>\n",
       "      <td>0.101335</td>\n",
       "      <td>-0.252006</td>\n",
       "      <td>0.139274</td>\n",
       "      <td>-0.179060</td>\n",
       "      <td>0.141302</td>\n",
       "      <td>0.070079</td>\n",
       "      <td>-0.207299</td>\n",
       "      <td>-0.000269</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>31</th>\n",
       "      <td>0.189339</td>\n",
       "      <td>-0.119866</td>\n",
       "      <td>-0.079744</td>\n",
       "      <td>0.092221</td>\n",
       "      <td>-0.261133</td>\n",
       "      <td>0.111370</td>\n",
       "      <td>-0.178375</td>\n",
       "      <td>0.140752</td>\n",
       "      <td>-0.063321</td>\n",
       "      <td>0.169724</td>\n",
       "      <td>-0.094306</td>\n",
       "      <td>-0.104317</td>\n",
       "      <td>0.234894</td>\n",
       "      <td>0.152246</td>\n",
       "      <td>0.197570</td>\n",
       "      <td>-0.120558</td>\n",
       "      <td>0.115742</td>\n",
       "      <td>-0.111452</td>\n",
       "      <td>0.023526</td>\n",
       "      <td>-0.038866</td>\n",
       "      <td>0.076540</td>\n",
       "      <td>0.117855</td>\n",
       "      <td>-0.226199</td>\n",
       "      <td>0.067255</td>\n",
       "      <td>-0.198613</td>\n",
       "      <td>-0.056154</td>\n",
       "      <td>0.018708</td>\n",
       "      <td>-0.080102</td>\n",
       "      <td>0.021918</td>\n",
       "      <td>0.216289</td>\n",
       "      <td>-0.145829</td>\n",
       "      <td>-0.082783</td>\n",
       "      <td>-0.273195</td>\n",
       "      <td>-0.070384</td>\n",
       "      <td>-0.011450</td>\n",
       "      <td>0.028104</td>\n",
       "      <td>0.136580</td>\n",
       "      <td>-0.037416</td>\n",
       "      <td>0.337059</td>\n",
       "      <td>-0.067977</td>\n",
       "      <td>0.190594</td>\n",
       "      <td>-0.340372</td>\n",
       "      <td>0.075458</td>\n",
       "      <td>0.100615</td>\n",
       "      <td>-0.116485</td>\n",
       "      <td>0.289413</td>\n",
       "      <td>0.015869</td>\n",
       "      <td>0.096098</td>\n",
       "      <td>-0.158919</td>\n",
       "      <td>0.102395</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.297327</td>\n",
       "      <td>-0.110280</td>\n",
       "      <td>0.314883</td>\n",
       "      <td>0.037993</td>\n",
       "      <td>-0.121426</td>\n",
       "      <td>0.080069</td>\n",
       "      <td>-0.051353</td>\n",
       "      <td>-0.005732</td>\n",
       "      <td>0.346907</td>\n",
       "      <td>0.217158</td>\n",
       "      <td>-0.039867</td>\n",
       "      <td>0.069222</td>\n",
       "      <td>0.026214</td>\n",
       "      <td>0.183347</td>\n",
       "      <td>0.082554</td>\n",
       "      <td>-0.110395</td>\n",
       "      <td>-0.159624</td>\n",
       "      <td>0.196512</td>\n",
       "      <td>-0.118962</td>\n",
       "      <td>0.037858</td>\n",
       "      <td>-0.248131</td>\n",
       "      <td>-0.096747</td>\n",
       "      <td>-0.088551</td>\n",
       "      <td>-0.156313</td>\n",
       "      <td>0.269707</td>\n",
       "      <td>0.069541</td>\n",
       "      <td>0.273193</td>\n",
       "      <td>0.043300</td>\n",
       "      <td>-0.071691</td>\n",
       "      <td>0.026775</td>\n",
       "      <td>0.138172</td>\n",
       "      <td>0.171680</td>\n",
       "      <td>-0.168258</td>\n",
       "      <td>-0.039567</td>\n",
       "      <td>-0.004076</td>\n",
       "      <td>-0.137948</td>\n",
       "      <td>-0.079907</td>\n",
       "      <td>-0.301279</td>\n",
       "      <td>0.001725</td>\n",
       "      <td>0.010904</td>\n",
       "      <td>-0.150079</td>\n",
       "      <td>-0.123784</td>\n",
       "      <td>0.093104</td>\n",
       "      <td>-0.156096</td>\n",
       "      <td>-0.009104</td>\n",
       "      <td>-0.222801</td>\n",
       "      <td>0.038339</td>\n",
       "      <td>-0.040449</td>\n",
       "      <td>-0.293521</td>\n",
       "      <td>0.078984</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>32</th>\n",
       "      <td>0.075971</td>\n",
       "      <td>-0.094451</td>\n",
       "      <td>-0.121038</td>\n",
       "      <td>0.203420</td>\n",
       "      <td>-0.227617</td>\n",
       "      <td>0.210452</td>\n",
       "      <td>-0.133984</td>\n",
       "      <td>0.147263</td>\n",
       "      <td>-0.042056</td>\n",
       "      <td>0.309453</td>\n",
       "      <td>-0.174447</td>\n",
       "      <td>-0.045038</td>\n",
       "      <td>0.216985</td>\n",
       "      <td>0.144115</td>\n",
       "      <td>0.117917</td>\n",
       "      <td>-0.159027</td>\n",
       "      <td>-0.030355</td>\n",
       "      <td>-0.114750</td>\n",
       "      <td>0.116906</td>\n",
       "      <td>-0.050505</td>\n",
       "      <td>0.105867</td>\n",
       "      <td>0.031210</td>\n",
       "      <td>-0.306992</td>\n",
       "      <td>0.045962</td>\n",
       "      <td>-0.247908</td>\n",
       "      <td>0.016675</td>\n",
       "      <td>0.057747</td>\n",
       "      <td>-0.135679</td>\n",
       "      <td>0.073391</td>\n",
       "      <td>0.149101</td>\n",
       "      <td>-0.158457</td>\n",
       "      <td>-0.009534</td>\n",
       "      <td>-0.316855</td>\n",
       "      <td>-0.117881</td>\n",
       "      <td>-0.054732</td>\n",
       "      <td>-0.022312</td>\n",
       "      <td>0.182867</td>\n",
       "      <td>-0.078445</td>\n",
       "      <td>0.332517</td>\n",
       "      <td>-0.060599</td>\n",
       "      <td>0.174434</td>\n",
       "      <td>-0.261032</td>\n",
       "      <td>0.066373</td>\n",
       "      <td>0.095539</td>\n",
       "      <td>-0.061595</td>\n",
       "      <td>0.318540</td>\n",
       "      <td>0.031794</td>\n",
       "      <td>0.063122</td>\n",
       "      <td>-0.187572</td>\n",
       "      <td>-0.063557</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.357718</td>\n",
       "      <td>-0.180175</td>\n",
       "      <td>0.271572</td>\n",
       "      <td>-0.103505</td>\n",
       "      <td>0.000388</td>\n",
       "      <td>0.126278</td>\n",
       "      <td>-0.039390</td>\n",
       "      <td>0.078637</td>\n",
       "      <td>0.262082</td>\n",
       "      <td>0.238497</td>\n",
       "      <td>-0.026010</td>\n",
       "      <td>-0.007262</td>\n",
       "      <td>0.017062</td>\n",
       "      <td>0.150394</td>\n",
       "      <td>0.094532</td>\n",
       "      <td>0.010042</td>\n",
       "      <td>-0.177889</td>\n",
       "      <td>0.229175</td>\n",
       "      <td>-0.141875</td>\n",
       "      <td>-0.031037</td>\n",
       "      <td>-0.260227</td>\n",
       "      <td>-0.083882</td>\n",
       "      <td>-0.017693</td>\n",
       "      <td>-0.126679</td>\n",
       "      <td>0.273283</td>\n",
       "      <td>-0.004707</td>\n",
       "      <td>0.242953</td>\n",
       "      <td>-0.012938</td>\n",
       "      <td>0.037177</td>\n",
       "      <td>0.015244</td>\n",
       "      <td>0.133987</td>\n",
       "      <td>0.129389</td>\n",
       "      <td>-0.105907</td>\n",
       "      <td>-0.115963</td>\n",
       "      <td>-0.109523</td>\n",
       "      <td>-0.081627</td>\n",
       "      <td>-0.042385</td>\n",
       "      <td>-0.195018</td>\n",
       "      <td>-0.024508</td>\n",
       "      <td>0.027435</td>\n",
       "      <td>-0.152831</td>\n",
       "      <td>-0.156049</td>\n",
       "      <td>0.148977</td>\n",
       "      <td>-0.215037</td>\n",
       "      <td>0.067744</td>\n",
       "      <td>-0.147781</td>\n",
       "      <td>0.063533</td>\n",
       "      <td>0.019853</td>\n",
       "      <td>-0.264138</td>\n",
       "      <td>0.076567</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>33</th>\n",
       "      <td>0.126650</td>\n",
       "      <td>-0.161260</td>\n",
       "      <td>-0.079225</td>\n",
       "      <td>0.230853</td>\n",
       "      <td>-0.268507</td>\n",
       "      <td>0.120629</td>\n",
       "      <td>-0.119568</td>\n",
       "      <td>0.224075</td>\n",
       "      <td>-0.078936</td>\n",
       "      <td>0.373013</td>\n",
       "      <td>-0.148182</td>\n",
       "      <td>-0.063682</td>\n",
       "      <td>0.270447</td>\n",
       "      <td>0.209601</td>\n",
       "      <td>0.134872</td>\n",
       "      <td>-0.098807</td>\n",
       "      <td>0.057150</td>\n",
       "      <td>-0.162421</td>\n",
       "      <td>0.076060</td>\n",
       "      <td>0.024218</td>\n",
       "      <td>0.019050</td>\n",
       "      <td>0.050864</td>\n",
       "      <td>-0.361721</td>\n",
       "      <td>0.137796</td>\n",
       "      <td>-0.252521</td>\n",
       "      <td>-0.003827</td>\n",
       "      <td>0.035527</td>\n",
       "      <td>-0.175924</td>\n",
       "      <td>0.009173</td>\n",
       "      <td>0.204787</td>\n",
       "      <td>-0.115723</td>\n",
       "      <td>-0.062441</td>\n",
       "      <td>-0.219392</td>\n",
       "      <td>-0.090294</td>\n",
       "      <td>-0.048920</td>\n",
       "      <td>-0.018704</td>\n",
       "      <td>0.181719</td>\n",
       "      <td>-0.080907</td>\n",
       "      <td>0.336296</td>\n",
       "      <td>-0.038013</td>\n",
       "      <td>0.224661</td>\n",
       "      <td>-0.322600</td>\n",
       "      <td>0.073934</td>\n",
       "      <td>0.114055</td>\n",
       "      <td>-0.106442</td>\n",
       "      <td>0.377869</td>\n",
       "      <td>-0.017005</td>\n",
       "      <td>0.049750</td>\n",
       "      <td>-0.225043</td>\n",
       "      <td>-0.063040</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.288797</td>\n",
       "      <td>-0.186934</td>\n",
       "      <td>0.246011</td>\n",
       "      <td>-0.017289</td>\n",
       "      <td>-0.028672</td>\n",
       "      <td>0.077506</td>\n",
       "      <td>-0.016165</td>\n",
       "      <td>0.042528</td>\n",
       "      <td>0.308051</td>\n",
       "      <td>0.206544</td>\n",
       "      <td>-0.035256</td>\n",
       "      <td>-0.006429</td>\n",
       "      <td>0.038736</td>\n",
       "      <td>0.165597</td>\n",
       "      <td>0.012324</td>\n",
       "      <td>0.054892</td>\n",
       "      <td>-0.213561</td>\n",
       "      <td>0.309646</td>\n",
       "      <td>-0.119768</td>\n",
       "      <td>0.070219</td>\n",
       "      <td>-0.292171</td>\n",
       "      <td>-0.048727</td>\n",
       "      <td>-0.119255</td>\n",
       "      <td>-0.186697</td>\n",
       "      <td>0.279208</td>\n",
       "      <td>0.002578</td>\n",
       "      <td>0.167844</td>\n",
       "      <td>0.016094</td>\n",
       "      <td>0.093121</td>\n",
       "      <td>0.040056</td>\n",
       "      <td>0.155748</td>\n",
       "      <td>0.028421</td>\n",
       "      <td>-0.092949</td>\n",
       "      <td>-0.110219</td>\n",
       "      <td>-0.209964</td>\n",
       "      <td>-0.030257</td>\n",
       "      <td>0.036953</td>\n",
       "      <td>-0.194668</td>\n",
       "      <td>-0.010599</td>\n",
       "      <td>-0.030985</td>\n",
       "      <td>-0.125480</td>\n",
       "      <td>-0.033785</td>\n",
       "      <td>0.096790</td>\n",
       "      <td>-0.226827</td>\n",
       "      <td>0.116466</td>\n",
       "      <td>-0.138222</td>\n",
       "      <td>0.158516</td>\n",
       "      <td>0.046179</td>\n",
       "      <td>-0.216379</td>\n",
       "      <td>0.023215</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>34</th>\n",
       "      <td>0.056864</td>\n",
       "      <td>-0.005315</td>\n",
       "      <td>-0.078913</td>\n",
       "      <td>0.219385</td>\n",
       "      <td>-0.189082</td>\n",
       "      <td>0.145239</td>\n",
       "      <td>-0.131909</td>\n",
       "      <td>0.205832</td>\n",
       "      <td>-0.059607</td>\n",
       "      <td>0.266310</td>\n",
       "      <td>-0.169353</td>\n",
       "      <td>-0.061437</td>\n",
       "      <td>0.246569</td>\n",
       "      <td>0.192097</td>\n",
       "      <td>0.177971</td>\n",
       "      <td>-0.112546</td>\n",
       "      <td>0.001879</td>\n",
       "      <td>-0.084509</td>\n",
       "      <td>0.128525</td>\n",
       "      <td>0.025893</td>\n",
       "      <td>0.007944</td>\n",
       "      <td>0.054444</td>\n",
       "      <td>-0.248874</td>\n",
       "      <td>0.084552</td>\n",
       "      <td>-0.237019</td>\n",
       "      <td>-0.024078</td>\n",
       "      <td>0.098776</td>\n",
       "      <td>-0.105593</td>\n",
       "      <td>0.017116</td>\n",
       "      <td>0.179930</td>\n",
       "      <td>-0.109365</td>\n",
       "      <td>-0.051005</td>\n",
       "      <td>-0.287867</td>\n",
       "      <td>-0.059736</td>\n",
       "      <td>-0.048974</td>\n",
       "      <td>0.089346</td>\n",
       "      <td>0.150783</td>\n",
       "      <td>-0.138510</td>\n",
       "      <td>0.353545</td>\n",
       "      <td>-0.078222</td>\n",
       "      <td>0.114439</td>\n",
       "      <td>-0.255776</td>\n",
       "      <td>0.129901</td>\n",
       "      <td>0.093280</td>\n",
       "      <td>-0.107746</td>\n",
       "      <td>0.360857</td>\n",
       "      <td>-0.005196</td>\n",
       "      <td>0.091342</td>\n",
       "      <td>-0.157933</td>\n",
       "      <td>-0.059031</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.340514</td>\n",
       "      <td>-0.232858</td>\n",
       "      <td>0.229838</td>\n",
       "      <td>-0.129290</td>\n",
       "      <td>-0.014740</td>\n",
       "      <td>0.141921</td>\n",
       "      <td>0.033097</td>\n",
       "      <td>0.112597</td>\n",
       "      <td>0.237371</td>\n",
       "      <td>0.162472</td>\n",
       "      <td>-0.010695</td>\n",
       "      <td>0.032579</td>\n",
       "      <td>-0.007787</td>\n",
       "      <td>0.181200</td>\n",
       "      <td>0.113059</td>\n",
       "      <td>0.028482</td>\n",
       "      <td>-0.099651</td>\n",
       "      <td>0.235777</td>\n",
       "      <td>-0.074017</td>\n",
       "      <td>-0.050050</td>\n",
       "      <td>-0.237854</td>\n",
       "      <td>-0.096115</td>\n",
       "      <td>-0.123257</td>\n",
       "      <td>-0.091915</td>\n",
       "      <td>0.329261</td>\n",
       "      <td>0.049985</td>\n",
       "      <td>0.252204</td>\n",
       "      <td>-0.067287</td>\n",
       "      <td>0.027662</td>\n",
       "      <td>-0.049665</td>\n",
       "      <td>0.094678</td>\n",
       "      <td>0.146909</td>\n",
       "      <td>-0.164621</td>\n",
       "      <td>-0.104167</td>\n",
       "      <td>-0.157322</td>\n",
       "      <td>-0.051571</td>\n",
       "      <td>0.005422</td>\n",
       "      <td>-0.215605</td>\n",
       "      <td>0.012652</td>\n",
       "      <td>0.063658</td>\n",
       "      <td>-0.165792</td>\n",
       "      <td>-0.107261</td>\n",
       "      <td>0.163903</td>\n",
       "      <td>-0.163548</td>\n",
       "      <td>0.167231</td>\n",
       "      <td>-0.143712</td>\n",
       "      <td>0.007238</td>\n",
       "      <td>-0.002465</td>\n",
       "      <td>-0.215374</td>\n",
       "      <td>-0.001107</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>35</th>\n",
       "      <td>0.123608</td>\n",
       "      <td>-0.078376</td>\n",
       "      <td>-0.106610</td>\n",
       "      <td>0.143527</td>\n",
       "      <td>-0.230589</td>\n",
       "      <td>0.149412</td>\n",
       "      <td>-0.094871</td>\n",
       "      <td>0.215000</td>\n",
       "      <td>-0.050330</td>\n",
       "      <td>0.259572</td>\n",
       "      <td>-0.165038</td>\n",
       "      <td>-0.127889</td>\n",
       "      <td>0.265977</td>\n",
       "      <td>0.141526</td>\n",
       "      <td>0.197833</td>\n",
       "      <td>-0.164755</td>\n",
       "      <td>0.103733</td>\n",
       "      <td>-0.105294</td>\n",
       "      <td>0.043690</td>\n",
       "      <td>0.003612</td>\n",
       "      <td>0.110246</td>\n",
       "      <td>0.057852</td>\n",
       "      <td>-0.283981</td>\n",
       "      <td>0.133845</td>\n",
       "      <td>-0.262784</td>\n",
       "      <td>-0.089360</td>\n",
       "      <td>0.076219</td>\n",
       "      <td>-0.090705</td>\n",
       "      <td>-0.021636</td>\n",
       "      <td>0.135594</td>\n",
       "      <td>-0.122401</td>\n",
       "      <td>-0.039765</td>\n",
       "      <td>-0.270881</td>\n",
       "      <td>-0.089649</td>\n",
       "      <td>-0.033248</td>\n",
       "      <td>0.026855</td>\n",
       "      <td>0.203845</td>\n",
       "      <td>-0.086387</td>\n",
       "      <td>0.328651</td>\n",
       "      <td>-0.089823</td>\n",
       "      <td>0.137541</td>\n",
       "      <td>-0.315793</td>\n",
       "      <td>0.080987</td>\n",
       "      <td>0.092921</td>\n",
       "      <td>-0.111436</td>\n",
       "      <td>0.355385</td>\n",
       "      <td>0.053140</td>\n",
       "      <td>0.041376</td>\n",
       "      <td>-0.173781</td>\n",
       "      <td>-0.031742</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.265176</td>\n",
       "      <td>-0.193260</td>\n",
       "      <td>0.284769</td>\n",
       "      <td>-0.064872</td>\n",
       "      <td>-0.042840</td>\n",
       "      <td>0.071011</td>\n",
       "      <td>0.029884</td>\n",
       "      <td>0.032217</td>\n",
       "      <td>0.295255</td>\n",
       "      <td>0.226087</td>\n",
       "      <td>-0.002175</td>\n",
       "      <td>0.028949</td>\n",
       "      <td>0.009290</td>\n",
       "      <td>0.131106</td>\n",
       "      <td>0.061326</td>\n",
       "      <td>-0.000481</td>\n",
       "      <td>-0.096942</td>\n",
       "      <td>0.220528</td>\n",
       "      <td>-0.132198</td>\n",
       "      <td>0.005512</td>\n",
       "      <td>-0.208902</td>\n",
       "      <td>-0.109697</td>\n",
       "      <td>-0.081802</td>\n",
       "      <td>-0.097309</td>\n",
       "      <td>0.283734</td>\n",
       "      <td>0.035150</td>\n",
       "      <td>0.230566</td>\n",
       "      <td>-0.041894</td>\n",
       "      <td>-0.048672</td>\n",
       "      <td>-0.034683</td>\n",
       "      <td>0.121709</td>\n",
       "      <td>0.150923</td>\n",
       "      <td>-0.079653</td>\n",
       "      <td>-0.079949</td>\n",
       "      <td>-0.113369</td>\n",
       "      <td>-0.077587</td>\n",
       "      <td>-0.013458</td>\n",
       "      <td>-0.181162</td>\n",
       "      <td>-0.025139</td>\n",
       "      <td>0.004943</td>\n",
       "      <td>-0.165945</td>\n",
       "      <td>-0.094067</td>\n",
       "      <td>0.175324</td>\n",
       "      <td>-0.182811</td>\n",
       "      <td>0.049791</td>\n",
       "      <td>-0.181773</td>\n",
       "      <td>0.042710</td>\n",
       "      <td>0.042621</td>\n",
       "      <td>-0.211761</td>\n",
       "      <td>0.020542</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "<p>36 rows × 5120 columns</p>\n",
       "</div>"
      ],
      "text/plain": [
       "        0         1         2         3         4         5         6     \\\n",
       "0   0.109975 -0.134590 -0.111443  0.218644 -0.237748  0.131493 -0.119502   \n",
       "1   0.129701 -0.184889 -0.115536  0.161651 -0.224050  0.112427 -0.157890   \n",
       "2   0.099468 -0.114953 -0.117187  0.183187 -0.209792  0.091260 -0.130392   \n",
       "3   0.156776 -0.105166 -0.063266  0.204592 -0.202521  0.076685 -0.140390   \n",
       "4   0.148965 -0.141826 -0.064849  0.198645 -0.237333  0.096351 -0.192772   \n",
       "5   0.136004 -0.134993 -0.085685  0.211411 -0.225582  0.071981 -0.150991   \n",
       "6   0.151536 -0.104399 -0.094527  0.160598 -0.209911  0.098383 -0.125450   \n",
       "7   0.145099 -0.090502 -0.107709  0.195208 -0.211850  0.060215 -0.166285   \n",
       "8   0.103065 -0.160759 -0.118862  0.199997 -0.200806  0.045798 -0.140664   \n",
       "9   0.099343 -0.111603 -0.109638  0.198031 -0.213136  0.085389 -0.112029   \n",
       "10  0.150078 -0.164752 -0.139190  0.164668 -0.218874  0.124772 -0.087845   \n",
       "11  0.115792 -0.108504 -0.095944  0.201081 -0.214380  0.148985 -0.134413   \n",
       "12  0.038375 -0.122354 -0.096294  0.185208 -0.246582  0.129750 -0.136116   \n",
       "13  0.120317 -0.121055 -0.064248  0.174359 -0.232488  0.117344 -0.165565   \n",
       "14  0.189981 -0.099620 -0.043858  0.121855 -0.223010  0.106480 -0.079413   \n",
       "15  0.102191 -0.099493 -0.058236  0.241401 -0.215121  0.104573 -0.169301   \n",
       "16  0.119033 -0.153783 -0.051925  0.181384 -0.247768  0.159741 -0.146779   \n",
       "17  0.157800 -0.118686 -0.150606  0.205409 -0.242001  0.111716 -0.137265   \n",
       "18  0.136303 -0.061476 -0.077046  0.206502 -0.223313  0.101852 -0.162581   \n",
       "19  0.139033 -0.122947 -0.111735  0.174526 -0.220552  0.051838 -0.162037   \n",
       "20  0.077037 -0.183716 -0.078878  0.221005 -0.225741  0.140500 -0.126052   \n",
       "21  0.108381 -0.081589 -0.055114  0.192622 -0.184780  0.147259 -0.164205   \n",
       "22  0.068633 -0.116530 -0.122826  0.191410 -0.212725  0.116594 -0.130537   \n",
       "23  0.145713 -0.101404 -0.125913  0.222237 -0.201406  0.128724 -0.109298   \n",
       "24  0.033266 -0.161788 -0.071069  0.208008 -0.216877  0.170222 -0.124472   \n",
       "25  0.110078 -0.165039 -0.088430  0.200475 -0.237514  0.151888 -0.083922   \n",
       "26  0.175475 -0.128516 -0.128148  0.216492 -0.247868  0.090050 -0.147215   \n",
       "27  0.068280 -0.143120 -0.111334  0.221054 -0.246314  0.107133 -0.151142   \n",
       "28  0.116597 -0.049208 -0.085304  0.274759 -0.238337  0.104141 -0.151078   \n",
       "29  0.109027 -0.166159 -0.122024  0.257628 -0.247994  0.102348 -0.130679   \n",
       "30  0.094652 -0.095609 -0.097690  0.187054 -0.244375  0.148235 -0.148863   \n",
       "31  0.189339 -0.119866 -0.079744  0.092221 -0.261133  0.111370 -0.178375   \n",
       "32  0.075971 -0.094451 -0.121038  0.203420 -0.227617  0.210452 -0.133984   \n",
       "33  0.126650 -0.161260 -0.079225  0.230853 -0.268507  0.120629 -0.119568   \n",
       "34  0.056864 -0.005315 -0.078913  0.219385 -0.189082  0.145239 -0.131909   \n",
       "35  0.123608 -0.078376 -0.106610  0.143527 -0.230589  0.149412 -0.094871   \n",
       "\n",
       "        7         8         9         10        11        12        13    \\\n",
       "0   0.234007 -0.042554  0.338132 -0.181911 -0.070123  0.285914  0.132456   \n",
       "1   0.269912 -0.049523  0.307800 -0.149578 -0.081749  0.265789  0.177847   \n",
       "2   0.256235 -0.053187  0.229403 -0.153716 -0.110329  0.224579  0.217258   \n",
       "3   0.251750 -0.082083  0.299491 -0.138542 -0.093754  0.238516  0.210513   \n",
       "4   0.201036 -0.055550  0.323271 -0.124018 -0.064344  0.264262  0.229667   \n",
       "5   0.161480 -0.096064  0.351003 -0.141241 -0.127765  0.251382  0.145000   \n",
       "6   0.240652 -0.009341  0.356902 -0.134509 -0.037678  0.257703  0.251786   \n",
       "7   0.217053 -0.059384  0.314212 -0.121815 -0.083672  0.243515  0.253559   \n",
       "8   0.254719 -0.080516  0.320600 -0.147457 -0.093887  0.218694  0.210146   \n",
       "9   0.204092 -0.058360  0.277055 -0.155110 -0.102247  0.266241  0.212752   \n",
       "10  0.302462 -0.020091  0.354497 -0.107631 -0.065878  0.178369  0.231036   \n",
       "11  0.193465 -0.050984  0.317283 -0.157609 -0.077027  0.272274  0.131107   \n",
       "12  0.261413 -0.050703  0.295339 -0.190413 -0.038232  0.229736  0.266636   \n",
       "13  0.214395 -0.018626  0.327004 -0.119045 -0.095545  0.282013  0.219324   \n",
       "14  0.148225 -0.104803  0.193760 -0.111376 -0.112515  0.288065  0.184379   \n",
       "15  0.206972 -0.086058  0.281521 -0.122076 -0.138420  0.286749  0.199947   \n",
       "16  0.150573  0.015509  0.325348 -0.151091 -0.096851  0.285886  0.278048   \n",
       "17  0.180476 -0.066203  0.368237 -0.156377 -0.078210  0.206123  0.196558   \n",
       "18  0.214483 -0.106981  0.300105 -0.162145 -0.066771  0.237164  0.192834   \n",
       "19  0.183666 -0.077523  0.303725 -0.121455 -0.120914  0.270511  0.226649   \n",
       "20  0.241651 -0.077915  0.311869 -0.202382 -0.063032  0.156356  0.174272   \n",
       "21  0.174979 -0.042993  0.263492 -0.181490 -0.041247  0.159774  0.206809   \n",
       "22  0.214973 -0.053687  0.219447 -0.176421 -0.074450  0.145990  0.239703   \n",
       "23  0.216365 -0.066860  0.325413 -0.193386 -0.072068  0.185118  0.083937   \n",
       "24  0.224440 -0.081342  0.322718 -0.176819 -0.079520  0.233964  0.206922   \n",
       "25  0.174967 -0.082083  0.258345 -0.135890 -0.064309  0.204680  0.199883   \n",
       "26  0.259016 -0.110687  0.279462 -0.111973 -0.111929  0.227249  0.226590   \n",
       "27  0.249594 -0.104961  0.236302 -0.203484 -0.093636  0.142345  0.250931   \n",
       "28  0.162720 -0.016946  0.270031 -0.128106 -0.139958  0.234293  0.235587   \n",
       "29  0.169716 -0.066886  0.307891 -0.146968 -0.067540  0.242495  0.188618   \n",
       "30  0.265033 -0.045692  0.277706 -0.136480 -0.111525  0.332094  0.189192   \n",
       "31  0.140752 -0.063321  0.169724 -0.094306 -0.104317  0.234894  0.152246   \n",
       "32  0.147263 -0.042056  0.309453 -0.174447 -0.045038  0.216985  0.144115   \n",
       "33  0.224075 -0.078936  0.373013 -0.148182 -0.063682  0.270447  0.209601   \n",
       "34  0.205832 -0.059607  0.266310 -0.169353 -0.061437  0.246569  0.192097   \n",
       "35  0.215000 -0.050330  0.259572 -0.165038 -0.127889  0.265977  0.141526   \n",
       "\n",
       "        14        15        16        17        18        19        20    \\\n",
       "0   0.145206 -0.119641  0.016052 -0.160409  0.175323  0.006981  0.031700   \n",
       "1   0.169391 -0.094384  0.128813 -0.176698  0.105074  0.014042  0.026007   \n",
       "2   0.185253 -0.137833  0.123428 -0.071266  0.113991 -0.005573  0.083241   \n",
       "3   0.224224 -0.099772  0.084619 -0.138276  0.065005  0.034831  0.028210   \n",
       "4   0.133730 -0.068402  0.067398 -0.159482  0.138655  0.017392 -0.027659   \n",
       "5   0.113196 -0.067518  0.019432 -0.200183  0.112800  0.025399  0.042380   \n",
       "6   0.107666 -0.069779  0.049223 -0.130719  0.139372 -0.011803  0.011799   \n",
       "7   0.178009 -0.088017  0.107953 -0.154144  0.077842  0.010119 -0.017940   \n",
       "8   0.162665 -0.084233  0.120447 -0.172108  0.132196  0.033965  0.058434   \n",
       "9   0.126143 -0.067549  0.095852 -0.139087  0.140236  0.008245  0.053534   \n",
       "10  0.141611 -0.089268  0.100422 -0.203566  0.096538  0.008184  0.036038   \n",
       "11  0.122000 -0.118348 -0.028966 -0.129934  0.200150 -0.009556  0.055637   \n",
       "12  0.218819 -0.110686  0.086804 -0.144453  0.022403  0.043655 -0.001109   \n",
       "13  0.102566 -0.073750  0.030573 -0.124610  0.172989  0.024975 -0.001409   \n",
       "14  0.237830 -0.169967  0.165410 -0.108414  0.057439  0.003095  0.084068   \n",
       "15  0.136107 -0.052422 -0.014880 -0.119737  0.163019  0.091869  0.008481   \n",
       "16  0.142507 -0.085697  0.061194 -0.082059  0.097556  0.001971 -0.051151   \n",
       "17  0.151126 -0.077988  0.026512 -0.242836  0.100818  0.013725  0.030066   \n",
       "18  0.217991 -0.060120  0.071474 -0.123842  0.067547  0.036414  0.060337   \n",
       "19  0.128650 -0.064698  0.088564 -0.136231  0.133351  0.053284  0.015309   \n",
       "20  0.144820 -0.106638 -0.005458 -0.191305  0.125788 -0.021658 -0.020402   \n",
       "21  0.205405 -0.142261  0.052151 -0.087046  0.066039 -0.028631 -0.011960   \n",
       "22  0.201505 -0.117848  0.076289 -0.038788  0.095666  0.022654  0.041330   \n",
       "23  0.128757 -0.176697 -0.029923 -0.189268  0.148491 -0.037742  0.112322   \n",
       "24  0.140089 -0.129153 -0.044857 -0.087826  0.066613  0.000763 -0.015396   \n",
       "25  0.137611 -0.115061 -0.024605 -0.042803  0.131858 -0.012668  0.051934   \n",
       "26  0.184725 -0.101531  0.066842 -0.134927  0.044560 -0.009920  0.100811   \n",
       "27  0.204709 -0.116570  0.015593 -0.131217  0.029938  0.048693  0.049763   \n",
       "28  0.151791 -0.052878  0.044726 -0.132298  0.079090  0.006276 -0.024541   \n",
       "29  0.146738 -0.110729  0.108971 -0.173095  0.126173 -0.006610  0.055242   \n",
       "30  0.137897 -0.105132  0.092612 -0.193866  0.120582  0.028512  0.022100   \n",
       "31  0.197570 -0.120558  0.115742 -0.111452  0.023526 -0.038866  0.076540   \n",
       "32  0.117917 -0.159027 -0.030355 -0.114750  0.116906 -0.050505  0.105867   \n",
       "33  0.134872 -0.098807  0.057150 -0.162421  0.076060  0.024218  0.019050   \n",
       "34  0.177971 -0.112546  0.001879 -0.084509  0.128525  0.025893  0.007944   \n",
       "35  0.197833 -0.164755  0.103733 -0.105294  0.043690  0.003612  0.110246   \n",
       "\n",
       "        21        22        23        24        25        26        27    \\\n",
       "0   0.035921 -0.388611  0.106619 -0.263324  0.010144  0.089600 -0.232413   \n",
       "1   0.069966 -0.333289  0.142775 -0.248938 -0.029828  0.020388 -0.144963   \n",
       "2   0.095849 -0.291120  0.084410 -0.293609 -0.046842  0.064312 -0.096830   \n",
       "3   0.085703 -0.210246  0.129641 -0.316469 -0.079329  0.070912 -0.132105   \n",
       "4   0.068616 -0.278606  0.146272 -0.246894  0.013924  0.095527 -0.171700   \n",
       "5   0.043313 -0.374516  0.148690 -0.285326 -0.031373  0.026149 -0.138682   \n",
       "6   0.043847 -0.303011  0.056028 -0.282500  0.017496  0.102216 -0.225272   \n",
       "7   0.051884 -0.242562  0.081285 -0.289248 -0.005200  0.085861 -0.171394   \n",
       "8   0.072425 -0.309210  0.125021 -0.286596 -0.035912  0.067374 -0.176865   \n",
       "9   0.068318 -0.313729  0.115662 -0.302197 -0.070243  0.075967 -0.139530   \n",
       "10  0.021989 -0.362100  0.102716 -0.228419 -0.006532  0.073238 -0.176172   \n",
       "11  0.031063 -0.383756  0.095411 -0.241722  0.010062  0.083183 -0.208177   \n",
       "12  0.084221 -0.197743  0.107413 -0.265296 -0.061734  0.054527 -0.105054   \n",
       "13  0.048996 -0.292034  0.072753 -0.271898 -0.001238  0.105216 -0.210466   \n",
       "14  0.141730 -0.139191  0.122362 -0.235837 -0.069561  0.127322 -0.036462   \n",
       "15  0.072334 -0.336468  0.129277 -0.278159 -0.006612  0.089056 -0.145332   \n",
       "16  0.082288 -0.352009  0.068670 -0.260803  0.036818  0.115875 -0.170938   \n",
       "17  0.005728 -0.345935  0.146713 -0.295815 -0.000897  0.021820 -0.168606   \n",
       "18  0.096562 -0.218304  0.114091 -0.317158 -0.084755  0.087118 -0.108638   \n",
       "19  0.059807 -0.302682  0.102252 -0.299771 -0.048789  0.057047 -0.176973   \n",
       "20 -0.003678 -0.434763  0.111055 -0.277104  0.043994  0.101196 -0.202132   \n",
       "21  0.096913 -0.170000  0.058858 -0.286215 -0.002488  0.124444 -0.101212   \n",
       "22  0.118158 -0.206337  0.114029 -0.311457 -0.054921  0.083903 -0.067038   \n",
       "23  0.044258 -0.361242  0.084291 -0.300882  0.035149  0.060617 -0.197932   \n",
       "24  0.082149 -0.323721  0.112585 -0.288654  0.014755  0.051435 -0.115221   \n",
       "25  0.096876 -0.274776  0.122050 -0.254711 -0.004496  0.072682 -0.098179   \n",
       "26  0.094685 -0.172429  0.108198 -0.265909 -0.019480  0.111598 -0.092332   \n",
       "27  0.095102 -0.245136  0.086482 -0.296598 -0.051461  0.080661 -0.075639   \n",
       "28  0.069220 -0.275774  0.100916 -0.264087 -0.008081  0.062462 -0.180195   \n",
       "29  0.002200 -0.350678  0.065735 -0.253242  0.039975  0.097954 -0.187782   \n",
       "30  0.066255 -0.387258  0.183049 -0.226823 -0.043580  0.019720 -0.135307   \n",
       "31  0.117855 -0.226199  0.067255 -0.198613 -0.056154  0.018708 -0.080102   \n",
       "32  0.031210 -0.306992  0.045962 -0.247908  0.016675  0.057747 -0.135679   \n",
       "33  0.050864 -0.361721  0.137796 -0.252521 -0.003827  0.035527 -0.175924   \n",
       "34  0.054444 -0.248874  0.084552 -0.237019 -0.024078  0.098776 -0.105593   \n",
       "35  0.057852 -0.283981  0.133845 -0.262784 -0.089360  0.076219 -0.090705   \n",
       "\n",
       "        28        29        30        31        32        33        34    \\\n",
       "0   0.044148  0.205849 -0.088589 -0.051135 -0.249299 -0.100425 -0.034155   \n",
       "1   0.050747  0.161994 -0.136832 -0.064507 -0.254568 -0.029669 -0.057159   \n",
       "2   0.032436  0.084759 -0.103322 -0.039152 -0.284039 -0.067096 -0.115826   \n",
       "3  -0.009244  0.151050 -0.079498 -0.048807 -0.207856 -0.036181 -0.060802   \n",
       "4   0.061878  0.200426 -0.122619 -0.051666 -0.242424 -0.073361 -0.049876   \n",
       "5   0.048825  0.275923 -0.126320 -0.067819 -0.266768 -0.106991 -0.066906   \n",
       "6   0.071203  0.222345 -0.170881 -0.041774 -0.247629 -0.096048 -0.079126   \n",
       "7   0.031988  0.169021 -0.132753 -0.092317 -0.195003 -0.089841 -0.056232   \n",
       "8  -0.003582  0.136112 -0.102970 -0.020262 -0.254946 -0.071851 -0.094417   \n",
       "9  -0.007760  0.187956 -0.075757 -0.029322 -0.205248 -0.109351 -0.082544   \n",
       "10  0.070957  0.147334 -0.135310 -0.024889 -0.274770 -0.033369 -0.065689   \n",
       "11  0.041552  0.224658 -0.118344 -0.033593 -0.270024 -0.121885 -0.039426   \n",
       "12 -0.026064  0.108197 -0.145600 -0.056957 -0.254362 -0.045438 -0.059084   \n",
       "13  0.018057  0.257754 -0.112871 -0.036326 -0.240222 -0.094845 -0.035892   \n",
       "14  0.000151  0.101028 -0.093296 -0.030716 -0.284957 -0.079319 -0.015006   \n",
       "15  0.032628  0.223559 -0.075726 -0.054147 -0.263812 -0.092986 -0.032027   \n",
       "16  0.065302  0.159618 -0.147296 -0.025318 -0.257168 -0.087648 -0.055692   \n",
       "17  0.075197  0.255719 -0.177132 -0.078953 -0.276595 -0.121217 -0.093077   \n",
       "18 -0.033983  0.165166 -0.047793 -0.060727 -0.230026 -0.069550 -0.064082   \n",
       "19  0.019946  0.217371 -0.115397 -0.066101 -0.234748 -0.114943 -0.057049   \n",
       "20  0.032809  0.232892 -0.150309 -0.022421 -0.274582 -0.034008 -0.022457   \n",
       "21  0.004596  0.153619 -0.182718 -0.045681 -0.253282 -0.074058 -0.062720   \n",
       "22  0.007552  0.072820 -0.170625 -0.048674 -0.325056 -0.076302 -0.081698   \n",
       "23  0.007936  0.218270 -0.171300 -0.061869 -0.253635 -0.072974 -0.131612   \n",
       "24 -0.010049  0.161967 -0.173949 -0.021588 -0.268219 -0.067375 -0.024115   \n",
       "25  0.042528  0.122180 -0.160181  0.003436 -0.335380 -0.053382 -0.080513   \n",
       "26  0.032621  0.191839 -0.139661 -0.048391 -0.281992 -0.063394 -0.061228   \n",
       "27 -0.044463  0.135011 -0.146749 -0.042630 -0.259667 -0.067494 -0.075882   \n",
       "28  0.012465  0.281192 -0.088081 -0.105013 -0.264657 -0.103804 -0.086743   \n",
       "29  0.065891  0.172706 -0.101303 -0.029959 -0.207586 -0.108257 -0.059105   \n",
       "30 -0.026478  0.303840 -0.069351 -0.097274 -0.259993 -0.088982 -0.041849   \n",
       "31  0.021918  0.216289 -0.145829 -0.082783 -0.273195 -0.070384 -0.011450   \n",
       "32  0.073391  0.149101 -0.158457 -0.009534 -0.316855 -0.117881 -0.054732   \n",
       "33  0.009173  0.204787 -0.115723 -0.062441 -0.219392 -0.090294 -0.048920   \n",
       "34  0.017116  0.179930 -0.109365 -0.051005 -0.287867 -0.059736 -0.048974   \n",
       "35 -0.021636  0.135594 -0.122401 -0.039765 -0.270881 -0.089649 -0.033248   \n",
       "\n",
       "        35        36        37        38        39        40        41    \\\n",
       "0  -0.042539  0.145001 -0.053556  0.325825  0.009630  0.188548 -0.276242   \n",
       "1   0.031107  0.171488 -0.025439  0.370129 -0.041123  0.135727 -0.279007   \n",
       "2   0.051603  0.165042 -0.094658  0.376194 -0.128548  0.181254 -0.249639   \n",
       "3   0.062600  0.129042 -0.139074  0.310381 -0.097736  0.152451 -0.305469   \n",
       "4  -0.040541  0.204453 -0.116795  0.322868 -0.009307  0.217903 -0.199481   \n",
       "5   0.012900  0.148005 -0.067439  0.411065  0.014621  0.208669 -0.291705   \n",
       "6  -0.057848  0.188629 -0.075652  0.259454  0.031267  0.196929 -0.156773   \n",
       "7  -0.006460  0.152259 -0.090605  0.322471 -0.066294  0.193915 -0.225634   \n",
       "8   0.005748  0.146481 -0.095382  0.371635 -0.088203  0.228230 -0.282255   \n",
       "9  -0.012243  0.133883 -0.092317  0.335809 -0.063369  0.206054 -0.269107   \n",
       "10  0.014031  0.190904 -0.016036  0.353996  0.010716  0.127578 -0.161569   \n",
       "11 -0.045207  0.149154 -0.069405  0.308419  0.013589  0.164959 -0.254017   \n",
       "12  0.075778  0.132040 -0.080114  0.339599 -0.111337  0.094832 -0.238816   \n",
       "13 -0.038089  0.175621 -0.099115  0.289955  0.017061  0.203475 -0.203858   \n",
       "14  0.072996  0.199853 -0.133236  0.325790 -0.095498  0.090839 -0.339671   \n",
       "15  0.065049  0.120588 -0.102302  0.383077 -0.028744  0.173533 -0.246471   \n",
       "16 -0.037980  0.156549 -0.096878  0.307695 -0.081831  0.208126 -0.218307   \n",
       "17 -0.027708  0.203718 -0.023698  0.379397  0.052573  0.173632 -0.215421   \n",
       "18  0.063639  0.136363 -0.148054  0.353077 -0.060597  0.173821 -0.317670   \n",
       "19  0.020394  0.136016 -0.115080  0.374386 -0.047619  0.232728 -0.275760   \n",
       "20 -0.033592  0.153044  0.036082  0.343732 -0.001198  0.192430 -0.248471   \n",
       "21  0.048979  0.152726 -0.119026  0.281551 -0.055195  0.120447 -0.282217   \n",
       "22  0.083015  0.178071 -0.111612  0.327810 -0.116179  0.131110 -0.242640   \n",
       "23 -0.052320  0.183731 -0.027726  0.351872  0.049659  0.208683 -0.234929   \n",
       "24 -0.002154  0.217863 -0.076387  0.278421 -0.066007  0.148879 -0.276389   \n",
       "25  0.015533  0.202166 -0.130769  0.324284 -0.081831  0.124339 -0.228217   \n",
       "26  0.084730  0.170180 -0.112418  0.364602 -0.081842  0.214739 -0.326534   \n",
       "27  0.062792  0.160358 -0.120987  0.337587 -0.099148  0.148384 -0.257090   \n",
       "28  0.024948  0.116364 -0.077394  0.362752 -0.025464  0.203469 -0.234783   \n",
       "29 -0.091941  0.196308 -0.085058  0.329245 -0.045768  0.260565 -0.269938   \n",
       "30  0.020321  0.185650 -0.051020  0.394498  0.032651  0.169578 -0.279043   \n",
       "31  0.028104  0.136580 -0.037416  0.337059 -0.067977  0.190594 -0.340372   \n",
       "32 -0.022312  0.182867 -0.078445  0.332517 -0.060599  0.174434 -0.261032   \n",
       "33 -0.018704  0.181719 -0.080907  0.336296 -0.038013  0.224661 -0.322600   \n",
       "34  0.089346  0.150783 -0.138510  0.353545 -0.078222  0.114439 -0.255776   \n",
       "35  0.026855  0.203845 -0.086387  0.328651 -0.089823  0.137541 -0.315793   \n",
       "\n",
       "        42        43        44        45        46        47        48    \\\n",
       "0   0.057267  0.159372 -0.074977  0.383486 -0.059249  0.067180 -0.192458   \n",
       "1   0.066811  0.166149 -0.087821  0.364228 -0.020949  0.117404 -0.246447   \n",
       "2   0.065785  0.160171 -0.091013  0.350580  0.005549  0.078152 -0.205696   \n",
       "3   0.069221  0.137120 -0.135764  0.433612 -0.017008  0.039403 -0.203412   \n",
       "4   0.109172  0.160647 -0.063116  0.359294 -0.020825  0.074966 -0.214306   \n",
       "5   0.108402  0.089902 -0.058351  0.406005 -0.067683  0.007932 -0.272992   \n",
       "6   0.066318  0.127572 -0.083622  0.329473 -0.018745  0.091129 -0.179197   \n",
       "7   0.075350  0.118398 -0.121993  0.414488 -0.006090  0.071920 -0.198899   \n",
       "8   0.097140  0.125881 -0.058326  0.423827 -0.029999  0.086932 -0.267964   \n",
       "9   0.088131  0.130078 -0.077731  0.450993  0.002878  0.051389 -0.187067   \n",
       "10  0.018056  0.134625 -0.076073  0.344225 -0.042800  0.106303 -0.222892   \n",
       "11  0.102697  0.150631 -0.055280  0.373151 -0.062987  0.061949 -0.196161   \n",
       "12  0.056826  0.135097 -0.142426  0.373937  0.064764  0.133505 -0.192966   \n",
       "13  0.095819  0.162732 -0.116114  0.338927 -0.040147  0.065871 -0.194454   \n",
       "14  0.122503  0.078338 -0.140163  0.372474 -0.001720  0.111966 -0.220115   \n",
       "15  0.168547  0.146214 -0.064242  0.432962 -0.061124  0.049675 -0.223034   \n",
       "16  0.039142  0.128212 -0.131671  0.328037 -0.018745  0.077934 -0.222961   \n",
       "17  0.052578  0.077885 -0.079277  0.334538 -0.037508  0.080958 -0.203167   \n",
       "18  0.102959  0.144486 -0.121943  0.421104  0.032542  0.045617 -0.220814   \n",
       "19  0.125658  0.121551 -0.096775  0.438111 -0.008546  0.041092 -0.246069   \n",
       "20  0.055220  0.161393 -0.069308  0.347031 -0.037571  0.066892 -0.243974   \n",
       "21  0.048652  0.057211 -0.154303  0.347232  0.086475  0.049577 -0.191751   \n",
       "22  0.054334  0.119811 -0.150140  0.337917  0.011412  0.126462 -0.239658   \n",
       "23  0.062586  0.103289 -0.038530  0.306830 -0.000457  0.041841 -0.160119   \n",
       "24  0.074848  0.101926 -0.080650  0.322797  0.021097  0.068251 -0.176109   \n",
       "25  0.055875  0.129623 -0.116583  0.284579  0.004653  0.127671 -0.241101   \n",
       "26  0.097163  0.089863 -0.101911  0.395987  0.027899  0.046090 -0.205421   \n",
       "27  0.050791  0.135780 -0.138661  0.363026  0.077660  0.133712 -0.237007   \n",
       "28  0.085146  0.137293 -0.119782  0.362535 -0.005930  0.062721 -0.217778   \n",
       "29  0.069752  0.080240 -0.044075  0.410438  0.004668  0.069785 -0.148011   \n",
       "30  0.114414  0.140740 -0.118944  0.402227 -0.008603  0.100816 -0.202231   \n",
       "31  0.075458  0.100615 -0.116485  0.289413  0.015869  0.096098 -0.158919   \n",
       "32  0.066373  0.095539 -0.061595  0.318540  0.031794  0.063122 -0.187572   \n",
       "33  0.073934  0.114055 -0.106442  0.377869 -0.017005  0.049750 -0.225043   \n",
       "34  0.129901  0.093280 -0.107746  0.360857 -0.005196  0.091342 -0.157933   \n",
       "35  0.080987  0.092921 -0.111436  0.355385  0.053140  0.041376 -0.173781   \n",
       "\n",
       "        49    ...      5070      5071      5072      5073      5074      5075  \\\n",
       "0  -0.160447  ... -0.287571 -0.199986  0.265588 -0.087591 -0.035537  0.052414   \n",
       "1  -0.102719  ... -0.252198 -0.117499  0.283669 -0.081878 -0.082878  0.056859   \n",
       "2  -0.069624  ... -0.265148 -0.125474  0.232081 -0.136144 -0.026184  0.075733   \n",
       "3  -0.054635  ... -0.269408 -0.143549  0.283143 -0.004776 -0.062685  0.133809   \n",
       "4  -0.116703  ... -0.260055 -0.118459  0.234262 -0.043266 -0.015988  0.069662   \n",
       "5  -0.127593  ... -0.182674 -0.099033  0.309982 -0.069400 -0.068808  0.061834   \n",
       "6  -0.081764  ... -0.301071 -0.092557  0.231172 -0.037784 -0.001100  0.045742   \n",
       "7  -0.075773  ... -0.261415 -0.149096  0.266664 -0.022508 -0.064983  0.061168   \n",
       "8  -0.059555  ... -0.190497 -0.068796  0.273971 -0.119400 -0.072194  0.062293   \n",
       "9  -0.116780  ... -0.250905 -0.153527  0.213915 -0.057285 -0.063084  0.109684   \n",
       "10 -0.088620  ... -0.298009 -0.144015  0.243391 -0.131867 -0.040785  0.091701   \n",
       "11 -0.158728  ... -0.315751 -0.188674  0.246871 -0.124228  0.002425  0.067850   \n",
       "12 -0.009309  ... -0.285787 -0.210788  0.304097 -0.035136 -0.041249  0.117025   \n",
       "13 -0.069315  ... -0.220470 -0.081250  0.200649 -0.075216 -0.004152  0.034934   \n",
       "14  0.040483  ... -0.257369 -0.194803  0.289560 -0.042378 -0.035136  0.019302   \n",
       "15 -0.125485  ... -0.243484 -0.139190  0.252767 -0.142362 -0.008536  0.080961   \n",
       "16  0.014172  ... -0.301292 -0.198801  0.266748 -0.068333  0.020373  0.050335   \n",
       "17 -0.107945  ... -0.305712 -0.171058  0.355773 -0.007645 -0.065319  0.074771   \n",
       "18 -0.068091  ... -0.266425 -0.168228  0.279185  0.007925 -0.085837  0.134813   \n",
       "19 -0.079388  ... -0.205297 -0.098522  0.264739 -0.081282 -0.050812  0.082191   \n",
       "20 -0.085056  ... -0.222701 -0.154216  0.257692 -0.133002 -0.049217  0.075391   \n",
       "21  0.011338  ... -0.318494 -0.189158  0.287165 -0.004630 -0.054570  0.085135   \n",
       "22  0.003721  ... -0.283057 -0.145005  0.278447 -0.123844  0.008364  0.088861   \n",
       "23 -0.156679  ... -0.299804 -0.113300  0.287763 -0.073148 -0.099946  0.064919   \n",
       "24 -0.026915  ... -0.357404 -0.266387  0.278025 -0.029581 -0.001778  0.114736   \n",
       "25 -0.003893  ... -0.322456 -0.224698  0.271277 -0.124126  0.020542  0.096496   \n",
       "26 -0.030896  ... -0.265901 -0.153907  0.281870  0.009714 -0.043309  0.129538   \n",
       "27  0.030092  ... -0.290918 -0.207489  0.310473 -0.024739 -0.105899  0.141126   \n",
       "28 -0.074803  ... -0.307709 -0.193954  0.293728 -0.024604 -0.036003  0.070311   \n",
       "29 -0.115484  ... -0.268022 -0.102675  0.214879 -0.037770 -0.081948  0.084980   \n",
       "30 -0.107559  ... -0.283304 -0.177984  0.317129 -0.065851 -0.084334  0.033224   \n",
       "31  0.102395  ... -0.297327 -0.110280  0.314883  0.037993 -0.121426  0.080069   \n",
       "32 -0.063557  ... -0.357718 -0.180175  0.271572 -0.103505  0.000388  0.126278   \n",
       "33 -0.063040  ... -0.288797 -0.186934  0.246011 -0.017289 -0.028672  0.077506   \n",
       "34 -0.059031  ... -0.340514 -0.232858  0.229838 -0.129290 -0.014740  0.141921   \n",
       "35 -0.031742  ... -0.265176 -0.193260  0.284769 -0.064872 -0.042840  0.071011   \n",
       "\n",
       "        5076      5077      5078      5079      5080      5081      5082  \\\n",
       "0  -0.032724  0.074804  0.253470  0.188196  0.000840 -0.048806  0.006446   \n",
       "1  -0.002050  0.037367  0.262278  0.109654  0.026107  0.013662  0.029625   \n",
       "2   0.041864  0.058491  0.310277  0.156786 -0.067325  0.029883  0.027132   \n",
       "3   0.033932  0.047367  0.329623  0.135072 -0.037661  0.074512  0.027695   \n",
       "4  -0.075061  0.032331  0.287921  0.133465 -0.023363  0.062305  0.053233   \n",
       "5  -0.050274  0.053250  0.308235  0.183944  0.006391 -0.007350  0.064807   \n",
       "6  -0.048358  0.065763  0.296345  0.181686 -0.010035  0.026769  0.035602   \n",
       "7  -0.002293  0.071659  0.354536  0.129104  0.002916  0.093137  0.011172   \n",
       "8  -0.018965  0.048422  0.312787  0.148791 -0.020733  0.077878  0.046454   \n",
       "9  -0.017103  0.047597  0.326154  0.176828 -0.023413  0.065649  0.011750   \n",
       "10 -0.007022  0.110253  0.235266  0.162594  0.044592 -0.040522  0.036766   \n",
       "11 -0.058481  0.090214  0.242821  0.205145  0.015614 -0.038904  0.020816   \n",
       "12  0.081218  0.072704  0.296876  0.105401 -0.016906  0.077851  0.006812   \n",
       "13 -0.067995  0.072879  0.305654  0.168654 -0.026132  0.025350  0.006906   \n",
       "14 -0.002439  0.037282  0.296227  0.165759 -0.087287  0.120988 -0.002333   \n",
       "15 -0.019042  0.102304  0.247494  0.153022  0.029064  0.027233  0.046584   \n",
       "16 -0.026783  0.050628  0.320089  0.182188 -0.015136  0.074301  0.050304   \n",
       "17 -0.023929  0.060666  0.297388  0.203568  0.019223 -0.004132  0.049873   \n",
       "18  0.006549  0.019470  0.300920  0.140518 -0.021785  0.110521 -0.006799   \n",
       "19 -0.028498  0.050510  0.336514  0.177148 -0.013568  0.084151  0.021187   \n",
       "20 -0.031818  0.087998  0.252650  0.162219 -0.009866 -0.087733  0.030578   \n",
       "21  0.039934  0.041021  0.294397  0.172836 -0.057209  0.060619  0.017376   \n",
       "22  0.051534  0.076604  0.264076  0.173068 -0.072581  0.033263  0.014161   \n",
       "23 -0.023141  0.126656  0.262134  0.202606  0.006136 -0.046622 -0.002979   \n",
       "24 -0.011721  0.097755  0.296347  0.186095 -0.022225  0.011246  0.008808   \n",
       "25 -0.007113  0.102541  0.219152  0.159148 -0.056704 -0.033739  0.047068   \n",
       "26 -0.012523  0.020251  0.325380  0.216869 -0.020758  0.110658  0.009731   \n",
       "27  0.038993  0.085714  0.316383  0.125881 -0.037108  0.066552  0.028385   \n",
       "28 -0.022755  0.119635  0.308824  0.147953  0.021667  0.062966 -0.012604   \n",
       "29 -0.043232  0.025902  0.323834  0.185922 -0.029285  0.048238  0.032020   \n",
       "30  0.015540  0.056321  0.286532  0.181740  0.003825  0.022871  0.047883   \n",
       "31 -0.051353 -0.005732  0.346907  0.217158 -0.039867  0.069222  0.026214   \n",
       "32 -0.039390  0.078637  0.262082  0.238497 -0.026010 -0.007262  0.017062   \n",
       "33 -0.016165  0.042528  0.308051  0.206544 -0.035256 -0.006429  0.038736   \n",
       "34  0.033097  0.112597  0.237371  0.162472 -0.010695  0.032579 -0.007787   \n",
       "35  0.029884  0.032217  0.295255  0.226087 -0.002175  0.028949  0.009290   \n",
       "\n",
       "        5083      5084      5085      5086      5087      5088      5089  \\\n",
       "0   0.150435  0.038589  0.085381 -0.230726  0.268536 -0.116890 -0.014526   \n",
       "1   0.179096  0.087634  0.068997 -0.194529  0.256631 -0.086368  0.013377   \n",
       "2   0.108766  0.068593 -0.053529 -0.139792  0.200807 -0.150195  0.036576   \n",
       "3   0.104189  0.026622  0.066428 -0.113747  0.263858 -0.121201  0.010072   \n",
       "4   0.157918  0.067226  0.141121 -0.213522  0.284241 -0.094832  0.043942   \n",
       "5   0.175300 -0.026430  0.075535 -0.168621  0.236126 -0.101624  0.068230   \n",
       "6   0.172235  0.089814  0.104018 -0.243346  0.248145 -0.103823  0.030160   \n",
       "7   0.151138  0.058742  0.101249 -0.190376  0.311007 -0.093571  0.031113   \n",
       "8   0.158741  0.022928  0.045851 -0.156927  0.236114 -0.098881  0.082307   \n",
       "9   0.079532 -0.002222  0.054662 -0.154906  0.264301 -0.128794  0.037420   \n",
       "10  0.204389  0.099569  0.043105 -0.204846  0.250286 -0.110963 -0.033590   \n",
       "11  0.153461  0.037507  0.081769 -0.236578  0.270648 -0.114520 -0.011366   \n",
       "12  0.164669  0.068866  0.046182 -0.106428  0.243790 -0.127053 -0.014188   \n",
       "13  0.145415  0.042224  0.104617 -0.226993  0.268139 -0.074999  0.054336   \n",
       "14  0.152132  0.118750 -0.046699 -0.095219  0.143039 -0.134040  0.006807   \n",
       "15  0.094876  0.003481  0.069172 -0.160779  0.253894 -0.103547  0.036547   \n",
       "16  0.171862  0.053688  0.054213 -0.177965  0.274620 -0.117158  0.057790   \n",
       "17  0.239919  0.051372  0.073958 -0.208709  0.253077 -0.081424 -0.004213   \n",
       "18  0.116738  0.028755  0.046989 -0.131090  0.214290 -0.122605  0.028768   \n",
       "19  0.111406 -0.017754  0.079834 -0.163347  0.275612 -0.110479  0.065496   \n",
       "20  0.193978  0.020966  0.013938 -0.201623  0.253537 -0.093881  0.021909   \n",
       "21  0.198594  0.076907  0.027844 -0.112461  0.226109 -0.121052 -0.001466   \n",
       "22  0.140409  0.123890 -0.017939 -0.103966  0.192167 -0.108350 -0.036111   \n",
       "23  0.229610  0.080771  0.069408 -0.204974  0.224885 -0.064545 -0.000130   \n",
       "24  0.178345  0.080846  0.003029 -0.165547  0.228465 -0.168007  0.023919   \n",
       "25  0.218816  0.073444 -0.080709 -0.211578  0.246042 -0.169766 -0.024663   \n",
       "26  0.155158  0.102541 -0.026054 -0.120567  0.240298 -0.166900 -0.023774   \n",
       "27  0.121593  0.030406 -0.021375 -0.106647  0.227662 -0.102719  0.001835   \n",
       "28  0.199840  0.044222  0.067166 -0.169962  0.307528 -0.042408  0.031395   \n",
       "29  0.121501 -0.010212  0.079603 -0.220643  0.298374 -0.100142  0.056994   \n",
       "30  0.201234  0.050664  0.030532 -0.176618  0.235617 -0.078661 -0.010192   \n",
       "31  0.183347  0.082554 -0.110395 -0.159624  0.196512 -0.118962  0.037858   \n",
       "32  0.150394  0.094532  0.010042 -0.177889  0.229175 -0.141875 -0.031037   \n",
       "33  0.165597  0.012324  0.054892 -0.213561  0.309646 -0.119768  0.070219   \n",
       "34  0.181200  0.113059  0.028482 -0.099651  0.235777 -0.074017 -0.050050   \n",
       "35  0.131106  0.061326 -0.000481 -0.096942  0.220528 -0.132198  0.005512   \n",
       "\n",
       "        5090      5091      5092      5093      5094      5095      5096  \\\n",
       "0  -0.264989 -0.072022 -0.083098 -0.169087  0.285792  0.045038  0.190472   \n",
       "1  -0.315640 -0.012413 -0.098380 -0.130370  0.274497  0.049318  0.221853   \n",
       "2  -0.200391 -0.061608 -0.052911 -0.173216  0.241643  0.071768  0.181315   \n",
       "3  -0.256017 -0.060592 -0.097629 -0.164075  0.268416 -0.001478  0.174371   \n",
       "4  -0.210025 -0.034361 -0.037393 -0.153350  0.274964  0.005359  0.149463   \n",
       "5  -0.302349  0.001756 -0.097639 -0.194145  0.320079 -0.000449  0.193450   \n",
       "6  -0.257891 -0.001675 -0.030990 -0.161538  0.265801  0.018294  0.182558   \n",
       "7  -0.295002 -0.060635 -0.131228 -0.106346  0.236142  0.037638  0.185169   \n",
       "8  -0.238682  0.003726 -0.033571 -0.180282  0.244027  0.053281  0.146560   \n",
       "9  -0.215849 -0.036923 -0.058880 -0.197312  0.261615 -0.006346  0.151438   \n",
       "10 -0.304709  0.004935 -0.061459 -0.125348  0.276709  0.053173  0.240315   \n",
       "11 -0.254067 -0.045520 -0.091991 -0.154352  0.287787  0.030450  0.196839   \n",
       "12 -0.303799 -0.084134 -0.151635 -0.088357  0.288222 -0.035630  0.256301   \n",
       "13 -0.209815  0.005642 -0.016829 -0.184797  0.275551  0.001305  0.134658   \n",
       "14 -0.196759 -0.157597 -0.113838 -0.076940  0.298091  0.015936  0.143178   \n",
       "15 -0.254178 -0.036223 -0.116226 -0.159439  0.312328  0.000788  0.154139   \n",
       "16 -0.260737 -0.037194 -0.067742 -0.140891  0.283212  0.033169  0.228327   \n",
       "17 -0.365345 -0.037336 -0.125068 -0.159977  0.312410  0.036051  0.257404   \n",
       "18 -0.244791 -0.101420 -0.156218 -0.161383  0.290095  0.033902  0.171926   \n",
       "19 -0.254530 -0.048219 -0.093828 -0.146886  0.260245  0.013238  0.150387   \n",
       "20 -0.252057  0.046438 -0.060296 -0.184460  0.267573  0.048974  0.193423   \n",
       "21 -0.291060 -0.112156 -0.067445 -0.117881  0.263439  0.060937  0.276333   \n",
       "22 -0.233682 -0.099015 -0.111950 -0.134761  0.325938  0.077487  0.213453   \n",
       "23 -0.274943 -0.045236 -0.099797 -0.200392  0.279266  0.071460  0.204050   \n",
       "24 -0.261253 -0.073074 -0.094644 -0.094901  0.306892 -0.056014  0.285901   \n",
       "25 -0.247924 -0.077050 -0.024093 -0.124654  0.302890  0.046415  0.246667   \n",
       "26 -0.283795 -0.058664 -0.065946 -0.165836  0.257677  0.024638  0.157943   \n",
       "27 -0.261946 -0.044614 -0.092806 -0.158293  0.285538 -0.002938  0.228986   \n",
       "28 -0.310558 -0.078147 -0.178513 -0.140652  0.296021  0.042895  0.207683   \n",
       "29 -0.220374 -0.007496  0.001573 -0.145973  0.228874  0.060474  0.143827   \n",
       "30 -0.291951 -0.059978 -0.174797 -0.164801  0.332326  0.047596  0.159567   \n",
       "31 -0.248131 -0.096747 -0.088551 -0.156313  0.269707  0.069541  0.273193   \n",
       "32 -0.260227 -0.083882 -0.017693 -0.126679  0.273283 -0.004707  0.242953   \n",
       "33 -0.292171 -0.048727 -0.119255 -0.186697  0.279208  0.002578  0.167844   \n",
       "34 -0.237854 -0.096115 -0.123257 -0.091915  0.329261  0.049985  0.252204   \n",
       "35 -0.208902 -0.109697 -0.081802 -0.097309  0.283734  0.035150  0.230566   \n",
       "\n",
       "        5097      5098      5099      5100      5101      5102      5103  \\\n",
       "0  -0.006061  0.086329 -0.000662  0.091908  0.035746 -0.148846 -0.118648   \n",
       "1  -0.059104  0.077843 -0.038710  0.128514  0.042598 -0.170303 -0.052412   \n",
       "2  -0.034740  0.006019 -0.071225  0.139590  0.150875 -0.073768 -0.083165   \n",
       "3  -0.048899  0.007231 -0.057600  0.130398  0.095052 -0.087395 -0.093361   \n",
       "4   0.052720  0.061115  0.042184  0.146574  0.046502 -0.084317 -0.089578   \n",
       "5   0.014595  0.011658  0.052489  0.116170  0.064921 -0.122043 -0.173016   \n",
       "6   0.102929  0.048266  0.041814  0.148157  0.009825 -0.118947 -0.064301   \n",
       "7   0.066991  0.055538 -0.039351  0.137819  0.030294 -0.101123 -0.116395   \n",
       "8  -0.013748  0.045135 -0.036612  0.139834  0.031850 -0.132258 -0.127275   \n",
       "9  -0.019252  0.027678 -0.064517  0.124614  0.055628 -0.082036 -0.137448   \n",
       "10 -0.028827  0.071875  0.023344  0.088318  0.024818 -0.136321 -0.045837   \n",
       "11 -0.006939  0.067371 -0.025671  0.105058  0.073961 -0.135288 -0.120844   \n",
       "12 -0.050371  0.009820 -0.037074  0.135655  0.072813 -0.108007 -0.074288   \n",
       "13  0.085755  0.063383  0.000179  0.122608  0.018554 -0.135003 -0.092231   \n",
       "14 -0.030893 -0.096511  0.009031  0.164422  0.151125 -0.059847 -0.060007   \n",
       "15 -0.069870  0.038898 -0.032237  0.123034  0.088775 -0.121829 -0.139446   \n",
       "16  0.039754  0.048385 -0.011748  0.174834  0.110390 -0.123504 -0.101839   \n",
       "17  0.052406  0.045977  0.080828  0.101054  0.014985 -0.129130 -0.102880   \n",
       "18 -0.040112 -0.004920 -0.000114  0.094790  0.110083 -0.095803 -0.123639   \n",
       "19  0.049474  0.015870 -0.028968  0.139070  0.022450 -0.107487 -0.163419   \n",
       "20  0.022759  0.122250  0.010786  0.119556  0.065383 -0.166989 -0.067826   \n",
       "21  0.031411 -0.014443 -0.006502  0.155565  0.098385 -0.105067 -0.102630   \n",
       "22 -0.052382  0.003257 -0.022888  0.190573  0.170840 -0.078206 -0.096388   \n",
       "23  0.001359  0.034640  0.028149  0.054354  0.030405 -0.125908 -0.058175   \n",
       "24 -0.038950  0.044506 -0.008231  0.141204  0.050306 -0.122646 -0.100723   \n",
       "25 -0.070088  0.030879  0.014932  0.175465  0.164267 -0.095272 -0.068908   \n",
       "26  0.014934 -0.014605  0.052121  0.136302  0.101943 -0.091247 -0.133936   \n",
       "27 -0.052771 -0.004690 -0.038297  0.169452  0.107938 -0.090290 -0.126887   \n",
       "28 -0.006534  0.019877 -0.000897  0.078116  0.056427 -0.114573 -0.114518   \n",
       "29  0.060814  0.061233 -0.002911  0.147292  0.020246 -0.095858 -0.144134   \n",
       "30 -0.056273  0.049838 -0.013237  0.082750  0.015319 -0.127518 -0.116965   \n",
       "31  0.043300 -0.071691  0.026775  0.138172  0.171680 -0.168258 -0.039567   \n",
       "32 -0.012938  0.037177  0.015244  0.133987  0.129389 -0.105907 -0.115963   \n",
       "33  0.016094  0.093121  0.040056  0.155748  0.028421 -0.092949 -0.110219   \n",
       "34 -0.067287  0.027662 -0.049665  0.094678  0.146909 -0.164621 -0.104167   \n",
       "35 -0.041894 -0.048672 -0.034683  0.121709  0.150923 -0.079653 -0.079949   \n",
       "\n",
       "        5104      5105      5106      5107      5108      5109      5110  \\\n",
       "0  -0.209491 -0.021450 -0.027162 -0.213849 -0.050013  0.006487 -0.136047   \n",
       "1  -0.178424 -0.050331 -0.044874 -0.277650  0.018790 -0.008888 -0.106790   \n",
       "2  -0.124568 -0.063161 -0.023962 -0.257893  0.000161  0.006935 -0.195330   \n",
       "3  -0.175921 -0.019632  0.030057 -0.268257 -0.003124 -0.005265 -0.100395   \n",
       "4  -0.209848 -0.013258  0.062758 -0.244171 -0.032025 -0.044478 -0.108473   \n",
       "5  -0.262249 -0.005773  0.038935 -0.247544 -0.086278  0.006853 -0.100689   \n",
       "6  -0.207114  0.008509  0.032465 -0.216733 -0.016382 -0.041606 -0.074308   \n",
       "7  -0.183114 -0.004973  0.041888 -0.145989  0.031941  0.008971 -0.085494   \n",
       "8  -0.238495 -0.023704 -0.005413 -0.196804 -0.020632 -0.016803 -0.110347   \n",
       "9  -0.224881 -0.027614 -0.000833 -0.208443 -0.011556  0.006449 -0.117023   \n",
       "10 -0.200750  0.005410 -0.037325 -0.247657  0.048043  0.020175 -0.046009   \n",
       "11 -0.191466 -0.041058 -0.020177 -0.214008 -0.059341  0.029301 -0.145702   \n",
       "12 -0.132788 -0.031031  0.024256 -0.188304  0.069645  0.022508 -0.151514   \n",
       "13 -0.258658 -0.009369  0.068916 -0.240644 -0.018663 -0.034235 -0.085768   \n",
       "14 -0.055120 -0.047606 -0.005355 -0.208166 -0.048341  0.014015 -0.160277   \n",
       "15 -0.217131 -0.039351  0.061298 -0.263394 -0.027513  0.061093 -0.102818   \n",
       "16 -0.137505 -0.057028  0.076221 -0.190554 -0.003539  0.011149 -0.107161   \n",
       "17 -0.180212  0.020306 -0.054750 -0.206388 -0.034011  0.013454 -0.065365   \n",
       "18 -0.195949 -0.033038  0.024126 -0.255053 -0.008551 -0.006948 -0.138308   \n",
       "19 -0.199246 -0.023974  0.058917 -0.193746 -0.017877  0.018693 -0.103422   \n",
       "20 -0.292029 -0.053049  0.035966 -0.203912 -0.005891 -0.003561 -0.085347   \n",
       "21 -0.113241 -0.093056  0.013762 -0.126994  0.028502  0.037380 -0.172519   \n",
       "22 -0.160876 -0.049031  0.005124 -0.232078  0.063473  0.027322 -0.185626   \n",
       "23 -0.155791 -0.036760 -0.052245 -0.258229 -0.052590  0.037014 -0.106041   \n",
       "24 -0.109429 -0.062236  0.027140 -0.168427 -0.006313  0.024699 -0.141803   \n",
       "25 -0.146437 -0.061429  0.016553 -0.266642 -0.021232  0.005664 -0.200571   \n",
       "26 -0.133265 -0.095080  0.008851 -0.268255  0.006170  0.003974 -0.088212   \n",
       "27 -0.163463 -0.074908  0.042002 -0.230969  0.056041  0.053460 -0.119225   \n",
       "28 -0.188509  0.017538  0.061767 -0.222352  0.070590  0.009440 -0.162331   \n",
       "29 -0.247790 -0.015183  0.000040 -0.142985 -0.066704 -0.032258 -0.120343   \n",
       "30 -0.200193 -0.045112  0.019443 -0.261863  0.005851  0.001197 -0.142963   \n",
       "31 -0.004076 -0.137948 -0.079907 -0.301279  0.001725  0.010904 -0.150079   \n",
       "32 -0.109523 -0.081627 -0.042385 -0.195018 -0.024508  0.027435 -0.152831   \n",
       "33 -0.209964 -0.030257  0.036953 -0.194668 -0.010599 -0.030985 -0.125480   \n",
       "34 -0.157322 -0.051571  0.005422 -0.215605  0.012652  0.063658 -0.165792   \n",
       "35 -0.113369 -0.077587 -0.013458 -0.181162 -0.025139  0.004943 -0.165945   \n",
       "\n",
       "        5111      5112      5113      5114      5115      5116      5117  \\\n",
       "0  -0.087660  0.107472 -0.270478  0.122341 -0.089307  0.137297  0.075365   \n",
       "1  -0.129787  0.076798 -0.208119  0.098149 -0.133004  0.089372  0.093026   \n",
       "2  -0.116773  0.137988 -0.164647  0.119364 -0.178338  0.031593  0.029154   \n",
       "3  -0.043842  0.144827 -0.125664  0.134358 -0.157067  0.040382  0.030294   \n",
       "4  -0.066790  0.079047 -0.211575  0.114173 -0.089037  0.146931  0.012782   \n",
       "5  -0.017608  0.153820 -0.266238  0.062926 -0.137164  0.161819  0.056334   \n",
       "6  -0.100192  0.048829 -0.188612  0.054384 -0.127758  0.144316  0.012221   \n",
       "7  -0.067918  0.110396 -0.136078  0.158490 -0.114540  0.084611  0.035289   \n",
       "8  -0.053039  0.131506 -0.230248  0.093026 -0.131159  0.117692  0.063887   \n",
       "9  -0.040955  0.128325 -0.189285  0.113435 -0.139380  0.119606  0.068152   \n",
       "10 -0.168293  0.039751 -0.207008  0.099637 -0.132462  0.100105  0.048275   \n",
       "11 -0.075578  0.129732 -0.261438  0.101597 -0.091607  0.138630  0.073024   \n",
       "12 -0.088697  0.123143 -0.146471  0.105474 -0.192358  0.039527  0.008083   \n",
       "13 -0.125209  0.048285 -0.237905  0.089749 -0.119637  0.194365  0.030610   \n",
       "14 -0.057837  0.182498 -0.187860  0.091341 -0.235567  0.012353 -0.006476   \n",
       "15 -0.056086  0.127391 -0.206826  0.172474 -0.145889  0.087672  0.062160   \n",
       "16 -0.075849  0.083053 -0.151076  0.082481 -0.100382  0.139618 -0.009169   \n",
       "17 -0.042283  0.122216 -0.206583  0.080122 -0.109054  0.087060  0.060336   \n",
       "18 -0.010194  0.149291 -0.141397  0.155086 -0.184331  0.052950 -0.007783   \n",
       "19 -0.037057  0.177018 -0.212298  0.103260 -0.132177  0.142974  0.046403   \n",
       "20 -0.121340  0.097155 -0.235379  0.083818 -0.100071  0.212479  0.091212   \n",
       "21 -0.064627  0.160005 -0.093198  0.069294 -0.156810  0.056858 -0.029199   \n",
       "22 -0.080397  0.160207 -0.123469  0.079884 -0.181897  0.015341 -0.022915   \n",
       "23 -0.102339  0.100616 -0.224136  0.038352 -0.140287  0.087144  0.055093   \n",
       "24 -0.102491  0.113387 -0.192079  0.119675 -0.164787  0.086681  0.024787   \n",
       "25 -0.105977  0.141263 -0.163351  0.034896 -0.190815  0.058171 -0.014313   \n",
       "26 -0.061540  0.139239 -0.128385  0.114811 -0.187927  0.053327 -0.027933   \n",
       "27 -0.062688  0.147356 -0.124680  0.094467 -0.194348  0.053529 -0.043625   \n",
       "28 -0.014711  0.134727 -0.169922  0.105697 -0.160824  0.122069 -0.006020   \n",
       "29 -0.088690  0.098280 -0.251099  0.097493 -0.109451  0.170236  0.067383   \n",
       "30 -0.040226  0.101335 -0.252006  0.139274 -0.179060  0.141302  0.070079   \n",
       "31 -0.123784  0.093104 -0.156096 -0.009104 -0.222801  0.038339 -0.040449   \n",
       "32 -0.156049  0.148977 -0.215037  0.067744 -0.147781  0.063533  0.019853   \n",
       "33 -0.033785  0.096790 -0.226827  0.116466 -0.138222  0.158516  0.046179   \n",
       "34 -0.107261  0.163903 -0.163548  0.167231 -0.143712  0.007238 -0.002465   \n",
       "35 -0.094067  0.175324 -0.182811  0.049791 -0.181773  0.042710  0.042621   \n",
       "\n",
       "        5118      5119  \n",
       "0  -0.198461 -0.035045  \n",
       "1  -0.170869 -0.013929  \n",
       "2  -0.215111 -0.017543  \n",
       "3  -0.248444  0.020361  \n",
       "4  -0.173229  0.016016  \n",
       "5  -0.224642 -0.034494  \n",
       "6  -0.232318  0.039383  \n",
       "7  -0.215635 -0.013522  \n",
       "8  -0.195390  0.012722  \n",
       "9  -0.199516 -0.006351  \n",
       "10 -0.188483 -0.005470  \n",
       "11 -0.212505  0.010496  \n",
       "12 -0.212721  0.027601  \n",
       "13 -0.202990  0.032436  \n",
       "14 -0.279787  0.032740  \n",
       "15 -0.187354 -0.035439  \n",
       "16 -0.223864  0.021656  \n",
       "17 -0.259084 -0.005970  \n",
       "18 -0.253648  0.059368  \n",
       "19 -0.212879  0.024435  \n",
       "20 -0.221482  0.040179  \n",
       "21 -0.288081 -0.004645  \n",
       "22 -0.252235 -0.001133  \n",
       "23 -0.235837  0.036125  \n",
       "24 -0.235165  0.074328  \n",
       "25 -0.282180  0.021420  \n",
       "26 -0.260661  0.081768  \n",
       "27 -0.254566  0.068075  \n",
       "28 -0.214408  0.029898  \n",
       "29 -0.160730 -0.026558  \n",
       "30 -0.207299 -0.000269  \n",
       "31 -0.293521  0.078984  \n",
       "32 -0.264138  0.076567  \n",
       "33 -0.216379  0.023215  \n",
       "34 -0.215374 -0.001107  \n",
       "35 -0.211761  0.020542  \n",
       "\n",
       "[36 rows x 5120 columns]"
      ]
     },
     "execution_count": 20,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "######################## Load the embedding ######################\n",
    "dir_path = 'data/embedding/esm2_15B_PG1_validation/'\n",
    "embeddings = {}\n",
    "for file in os.listdir(dir_path):\n",
    "        file_path = str(dir_path) + file \n",
    "        label = file.split('.pt')[0]\n",
    "        embeddings[label] = np.array(torch.load(file_path)['mean_representations'][48])\n",
    "\n",
    "\n",
    "# here I creating a dictionary with ID as key and semantic value as value \n",
    "data = meta_data.merge(pd.DataFrame.from_dict(embeddings, orient='index'), how='inner', left_on='ID2', right_index=True)\n",
    "\n",
    "\n",
    "features = data.iloc[:,meta_data.shape[1]:]\n",
    "features"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# Predictions on Validation set witn models v01 - feature selection with correlation"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Hemolysis "
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 21,
   "metadata": {},
   "outputs": [],
   "source": [
    "# Load the model\n",
    "model = joblib.load('models/model_v01.2_Lasso_esm2_15B_Hemolysis_regression_corr06.pkl')\n",
    "\n",
    "# load the list from the file\n",
    "with open('models/correlated_columns_v01.2_esm2_15B_hemolysis_corr06.pkl', 'rb') as f:\n",
    "    corr_columns = pickle.load(f)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 22,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "36"
      ]
     },
     "execution_count": 22,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "# calculates the the hemolysis score\n",
    "pred = model.predict(features[corr_columns])\n",
    "\n",
    "\n",
    "sum(pred <= 2)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 23,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
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       "<style scoped>\n",
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       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>ID</th>\n",
       "      <th>ID2</th>\n",
       "      <th>Sequence</th>\n",
       "      <th>RGGRLCYCRRRFCVCVGR</th>\n",
       "      <th>Select</th>\n",
       "      <th>Charge</th>\n",
       "      <th>group</th>\n",
       "      <th>MIC MH</th>\n",
       "      <th>%hemo</th>\n",
       "      <th>L10Select</th>\n",
       "      <th>hemolysis_pred_v01.2</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>PG1_3mut_1739000</td>\n",
       "      <td>bsPG-1.1</td>\n",
       "      <td>RGGRLQYCRRRFCVARGR</td>\n",
       "      <td>-----Q--------AR--</td>\n",
       "      <td>-0.82</td>\n",
       "      <td>6.742145</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>16</td>\n",
       "      <td>0.428850</td>\n",
       "      <td>0.836425</td>\n",
       "      <td>-7.675692</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>PG1_3mut_1218602</td>\n",
       "      <td>bsPG-1.2</td>\n",
       "      <td>RGGRLQYCRRRGCVTVGR</td>\n",
       "      <td>-----Q-----G--T---</td>\n",
       "      <td>-0.76</td>\n",
       "      <td>5.742155</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>4</td>\n",
       "      <td>0.341131</td>\n",
       "      <td>0.134981</td>\n",
       "      <td>-14.298704</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>PG1_3mut_1896424</td>\n",
       "      <td>bsPG-1.3</td>\n",
       "      <td>RGGRLAYCRRRDCTCVGR</td>\n",
       "      <td>-----A-----D-T----</td>\n",
       "      <td>-0.65</td>\n",
       "      <td>4.651497</td>\n",
       "      <td>CP</td>\n",
       "      <td>&gt;64</td>\n",
       "      <td>-0.165692</td>\n",
       "      <td>NaN</td>\n",
       "      <td>-14.385390</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>PG1_3mut_1275003</td>\n",
       "      <td>bsPG-1.4</td>\n",
       "      <td>RGGRLDYCRRRFCVTTGR</td>\n",
       "      <td>-----D--------TT--</td>\n",
       "      <td>-0.56</td>\n",
       "      <td>4.742406</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>64</td>\n",
       "      <td>0.165692</td>\n",
       "      <td>1.025482</td>\n",
       "      <td>-19.078636</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>PG1_3mut_257802</td>\n",
       "      <td>bsPG-1.5</td>\n",
       "      <td>RGGRLQACRRRFCVTVGR</td>\n",
       "      <td>-----QA-------T---</td>\n",
       "      <td>-0.44</td>\n",
       "      <td>5.744660</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>8</td>\n",
       "      <td>0.721248</td>\n",
       "      <td>0.761174</td>\n",
       "      <td>-3.053714</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "                 ID       ID2            Sequence  RGGRLCYCRRRFCVCVGR  Select  \\\n",
       "0  PG1_3mut_1739000  bsPG-1.1  RGGRLQYCRRRFCVARGR  -----Q--------AR--   -0.82   \n",
       "1  PG1_3mut_1218602  bsPG-1.2  RGGRLQYCRRRGCVTVGR  -----Q-----G--T---   -0.76   \n",
       "2  PG1_3mut_1896424  bsPG-1.3  RGGRLAYCRRRDCTCVGR  -----A-----D-T----   -0.65   \n",
       "3  PG1_3mut_1275003  bsPG-1.4  RGGRLDYCRRRFCVTTGR  -----D--------TT--   -0.56   \n",
       "4   PG1_3mut_257802  bsPG-1.5  RGGRLQACRRRFCVTVGR  -----QA-------T---   -0.44   \n",
       "\n",
       "     Charge   group MIC MH     %hemo  L10Select  hemolysis_pred_v01.2  \n",
       "0  6.742145  <-0.25     16  0.428850   0.836425             -7.675692  \n",
       "1  5.742155  <-0.25      4  0.341131   0.134981            -14.298704  \n",
       "2  4.651497      CP    >64 -0.165692        NaN            -14.385390  \n",
       "3  4.742406  <-0.25     64  0.165692   1.025482            -19.078636  \n",
       "4  5.744660  <-0.25      8  0.721248   0.761174             -3.053714  "
      ]
     },
     "execution_count": 23,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "meta_data['hemolysis_pred_v01.2'] = pred\n",
    "meta_data.head()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Selectivity"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 24,
   "metadata": {},
   "outputs": [],
   "source": [
    "# Load the model\n",
    "model = joblib.load('models/model_v01.2_SVR_esm2_15B_selectivity_regression_corr065.pkl')\n",
    "\n",
    "#load the list from the file\n",
    "with open('models/correlated_columns_v01.2_esm2_15B_selectivity_corr065.pkl', 'rb') as f:\n",
    "    correlated_columns = pickle.load(f)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 25,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "32"
      ]
     },
     "execution_count": 25,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "# calculates the the hemolysis score\n",
    "pred = model.predict(features[correlated_columns])\n",
    "sum(pred < 0.5)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 26,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
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       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>ID</th>\n",
       "      <th>ID2</th>\n",
       "      <th>Sequence</th>\n",
       "      <th>RGGRLCYCRRRFCVCVGR</th>\n",
       "      <th>Select</th>\n",
       "      <th>Charge</th>\n",
       "      <th>group</th>\n",
       "      <th>MIC MH</th>\n",
       "      <th>%hemo</th>\n",
       "      <th>L10Select</th>\n",
       "      <th>hemolysis_pred_v01.2</th>\n",
       "      <th>selectivity_pred_v01.2</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>PG1_3mut_1739000</td>\n",
       "      <td>bsPG-1.1</td>\n",
       "      <td>RGGRLQYCRRRFCVARGR</td>\n",
       "      <td>-----Q--------AR--</td>\n",
       "      <td>-0.82</td>\n",
       "      <td>6.742145</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>16</td>\n",
       "      <td>0.428850</td>\n",
       "      <td>0.836425</td>\n",
       "      <td>-7.675692</td>\n",
       "      <td>-0.987362</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>PG1_3mut_1218602</td>\n",
       "      <td>bsPG-1.2</td>\n",
       "      <td>RGGRLQYCRRRGCVTVGR</td>\n",
       "      <td>-----Q-----G--T---</td>\n",
       "      <td>-0.76</td>\n",
       "      <td>5.742155</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>4</td>\n",
       "      <td>0.341131</td>\n",
       "      <td>0.134981</td>\n",
       "      <td>-14.298704</td>\n",
       "      <td>-1.215473</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>PG1_3mut_1896424</td>\n",
       "      <td>bsPG-1.3</td>\n",
       "      <td>RGGRLAYCRRRDCTCVGR</td>\n",
       "      <td>-----A-----D-T----</td>\n",
       "      <td>-0.65</td>\n",
       "      <td>4.651497</td>\n",
       "      <td>CP</td>\n",
       "      <td>&gt;64</td>\n",
       "      <td>-0.165692</td>\n",
       "      <td>NaN</td>\n",
       "      <td>-14.385390</td>\n",
       "      <td>-1.305665</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>PG1_3mut_1275003</td>\n",
       "      <td>bsPG-1.4</td>\n",
       "      <td>RGGRLDYCRRRFCVTTGR</td>\n",
       "      <td>-----D--------TT--</td>\n",
       "      <td>-0.56</td>\n",
       "      <td>4.742406</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>64</td>\n",
       "      <td>0.165692</td>\n",
       "      <td>1.025482</td>\n",
       "      <td>-19.078636</td>\n",
       "      <td>-0.686002</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>PG1_3mut_257802</td>\n",
       "      <td>bsPG-1.5</td>\n",
       "      <td>RGGRLQACRRRFCVTVGR</td>\n",
       "      <td>-----QA-------T---</td>\n",
       "      <td>-0.44</td>\n",
       "      <td>5.744660</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>8</td>\n",
       "      <td>0.721248</td>\n",
       "      <td>0.761174</td>\n",
       "      <td>-3.053714</td>\n",
       "      <td>-0.247956</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "                 ID       ID2            Sequence  RGGRLCYCRRRFCVCVGR  Select  \\\n",
       "0  PG1_3mut_1739000  bsPG-1.1  RGGRLQYCRRRFCVARGR  -----Q--------AR--   -0.82   \n",
       "1  PG1_3mut_1218602  bsPG-1.2  RGGRLQYCRRRGCVTVGR  -----Q-----G--T---   -0.76   \n",
       "2  PG1_3mut_1896424  bsPG-1.3  RGGRLAYCRRRDCTCVGR  -----A-----D-T----   -0.65   \n",
       "3  PG1_3mut_1275003  bsPG-1.4  RGGRLDYCRRRFCVTTGR  -----D--------TT--   -0.56   \n",
       "4   PG1_3mut_257802  bsPG-1.5  RGGRLQACRRRFCVTVGR  -----QA-------T---   -0.44   \n",
       "\n",
       "     Charge   group MIC MH     %hemo  L10Select  hemolysis_pred_v01.2  \\\n",
       "0  6.742145  <-0.25     16  0.428850   0.836425             -7.675692   \n",
       "1  5.742155  <-0.25      4  0.341131   0.134981            -14.298704   \n",
       "2  4.651497      CP    >64 -0.165692        NaN            -14.385390   \n",
       "3  4.742406  <-0.25     64  0.165692   1.025482            -19.078636   \n",
       "4  5.744660  <-0.25      8  0.721248   0.761174             -3.053714   \n",
       "\n",
       "   selectivity_pred_v01.2  \n",
       "0               -0.987362  \n",
       "1               -1.215473  \n",
       "2               -1.305665  \n",
       "3               -0.686002  \n",
       "4               -0.247956  "
      ]
     },
     "execution_count": 26,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "meta_data['selectivity_pred_v01.2'] = pred\n",
    "meta_data.head()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Activity"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 27,
   "metadata": {},
   "outputs": [],
   "source": [
    "# save the model\n",
    "model = joblib.load('models/model_v01.2_GNB_esm2_15B_activity_classification_corr03.pkl')\n",
    "\n",
    "#load the list from the file\n",
    "with open('models/correlated_columns_v01.2_esm2_15B_activity_corr03.pkl', 'rb') as f:\n",
    "    correlated_columns = pickle.load(f)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 28,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "36"
      ]
     },
     "execution_count": 28,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "# calculates the probability of being active\n",
    "prob = model.predict_proba(features[correlated_columns])\n",
    "pred = (prob[:, 1] * 100).round(2)\n",
    "\n",
    "sum(pred == 100)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 29,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
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       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>ID</th>\n",
       "      <th>ID2</th>\n",
       "      <th>Sequence</th>\n",
       "      <th>RGGRLCYCRRRFCVCVGR</th>\n",
       "      <th>Select</th>\n",
       "      <th>Charge</th>\n",
       "      <th>group</th>\n",
       "      <th>MIC MH</th>\n",
       "      <th>%hemo</th>\n",
       "      <th>L10Select</th>\n",
       "      <th>hemolysis_pred_v01.2</th>\n",
       "      <th>selectivity_pred_v01.2</th>\n",
       "      <th>activity_pred_v01.2</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>PG1_3mut_1739000</td>\n",
       "      <td>bsPG-1.1</td>\n",
       "      <td>RGGRLQYCRRRFCVARGR</td>\n",
       "      <td>-----Q--------AR--</td>\n",
       "      <td>-0.82</td>\n",
       "      <td>6.742145</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>16</td>\n",
       "      <td>0.428850</td>\n",
       "      <td>0.836425</td>\n",
       "      <td>-7.675692</td>\n",
       "      <td>-0.987362</td>\n",
       "      <td>100.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>PG1_3mut_1218602</td>\n",
       "      <td>bsPG-1.2</td>\n",
       "      <td>RGGRLQYCRRRGCVTVGR</td>\n",
       "      <td>-----Q-----G--T---</td>\n",
       "      <td>-0.76</td>\n",
       "      <td>5.742155</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>4</td>\n",
       "      <td>0.341131</td>\n",
       "      <td>0.134981</td>\n",
       "      <td>-14.298704</td>\n",
       "      <td>-1.215473</td>\n",
       "      <td>100.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>PG1_3mut_1896424</td>\n",
       "      <td>bsPG-1.3</td>\n",
       "      <td>RGGRLAYCRRRDCTCVGR</td>\n",
       "      <td>-----A-----D-T----</td>\n",
       "      <td>-0.65</td>\n",
       "      <td>4.651497</td>\n",
       "      <td>CP</td>\n",
       "      <td>&gt;64</td>\n",
       "      <td>-0.165692</td>\n",
       "      <td>NaN</td>\n",
       "      <td>-14.385390</td>\n",
       "      <td>-1.305665</td>\n",
       "      <td>100.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>PG1_3mut_1275003</td>\n",
       "      <td>bsPG-1.4</td>\n",
       "      <td>RGGRLDYCRRRFCVTTGR</td>\n",
       "      <td>-----D--------TT--</td>\n",
       "      <td>-0.56</td>\n",
       "      <td>4.742406</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>64</td>\n",
       "      <td>0.165692</td>\n",
       "      <td>1.025482</td>\n",
       "      <td>-19.078636</td>\n",
       "      <td>-0.686002</td>\n",
       "      <td>100.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>PG1_3mut_257802</td>\n",
       "      <td>bsPG-1.5</td>\n",
       "      <td>RGGRLQACRRRFCVTVGR</td>\n",
       "      <td>-----QA-------T---</td>\n",
       "      <td>-0.44</td>\n",
       "      <td>5.744660</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>8</td>\n",
       "      <td>0.721248</td>\n",
       "      <td>0.761174</td>\n",
       "      <td>-3.053714</td>\n",
       "      <td>-0.247956</td>\n",
       "      <td>100.0</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "                 ID       ID2            Sequence  RGGRLCYCRRRFCVCVGR  Select  \\\n",
       "0  PG1_3mut_1739000  bsPG-1.1  RGGRLQYCRRRFCVARGR  -----Q--------AR--   -0.82   \n",
       "1  PG1_3mut_1218602  bsPG-1.2  RGGRLQYCRRRGCVTVGR  -----Q-----G--T---   -0.76   \n",
       "2  PG1_3mut_1896424  bsPG-1.3  RGGRLAYCRRRDCTCVGR  -----A-----D-T----   -0.65   \n",
       "3  PG1_3mut_1275003  bsPG-1.4  RGGRLDYCRRRFCVTTGR  -----D--------TT--   -0.56   \n",
       "4   PG1_3mut_257802  bsPG-1.5  RGGRLQACRRRFCVTVGR  -----QA-------T---   -0.44   \n",
       "\n",
       "     Charge   group MIC MH     %hemo  L10Select  hemolysis_pred_v01.2  \\\n",
       "0  6.742145  <-0.25     16  0.428850   0.836425             -7.675692   \n",
       "1  5.742155  <-0.25      4  0.341131   0.134981            -14.298704   \n",
       "2  4.651497      CP    >64 -0.165692        NaN            -14.385390   \n",
       "3  4.742406  <-0.25     64  0.165692   1.025482            -19.078636   \n",
       "4  5.744660  <-0.25      8  0.721248   0.761174             -3.053714   \n",
       "\n",
       "   selectivity_pred_v01.2  activity_pred_v01.2  \n",
       "0               -0.987362                100.0  \n",
       "1               -1.215473                100.0  \n",
       "2               -1.305665                100.0  \n",
       "3               -0.686002                100.0  \n",
       "4               -0.247956                100.0  "
      ]
     },
     "execution_count": 29,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "meta_data['activity_pred_v01.2'] = pred\n",
    "meta_data.head()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# Predictions on Validation set witn models v02 - feature selection with PCAs"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Hemolysis"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 33,
   "metadata": {},
   "outputs": [],
   "source": [
    "# Loading the model\n",
    "model = joblib.load('models/model_v02_Lasso30_esm2_15B_hemolysis_regression.pkl')\n",
    "\n",
    "# Loading PCA weights\n",
    "pca = joblib.load('models/weights_pca30_v02_esm2_15B_hemolysis.pkl')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 34,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "31"
      ]
     },
     "execution_count": 34,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "# calculates the probability of being active\n",
    "pred = model.predict(pca.transform(features))\n",
    "\n",
    "sum(pred <=2)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 35,
   "metadata": {},
   "outputs": [
    {
     "data": {
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       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>ID</th>\n",
       "      <th>ID2</th>\n",
       "      <th>Sequence</th>\n",
       "      <th>RGGRLCYCRRRFCVCVGR</th>\n",
       "      <th>Select</th>\n",
       "      <th>Charge</th>\n",
       "      <th>group</th>\n",
       "      <th>MIC MH</th>\n",
       "      <th>%hemo</th>\n",
       "      <th>L10Select</th>\n",
       "      <th>hemolysis_pred_v01.2</th>\n",
       "      <th>selectivity_pred_v01.2</th>\n",
       "      <th>activity_pred_v01.2</th>\n",
       "      <th>hemolysis_pred_v02</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>PG1_3mut_1739000</td>\n",
       "      <td>bsPG-1.1</td>\n",
       "      <td>RGGRLQYCRRRFCVARGR</td>\n",
       "      <td>-----Q--------AR--</td>\n",
       "      <td>-0.82</td>\n",
       "      <td>6.742145</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>16</td>\n",
       "      <td>0.428850</td>\n",
       "      <td>0.836425</td>\n",
       "      <td>-7.675692</td>\n",
       "      <td>-0.987362</td>\n",
       "      <td>100.0</td>\n",
       "      <td>-4.054558</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>PG1_3mut_1218602</td>\n",
       "      <td>bsPG-1.2</td>\n",
       "      <td>RGGRLQYCRRRGCVTVGR</td>\n",
       "      <td>-----Q-----G--T---</td>\n",
       "      <td>-0.76</td>\n",
       "      <td>5.742155</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>4</td>\n",
       "      <td>0.341131</td>\n",
       "      <td>0.134981</td>\n",
       "      <td>-14.298704</td>\n",
       "      <td>-1.215473</td>\n",
       "      <td>100.0</td>\n",
       "      <td>-6.763184</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>PG1_3mut_1896424</td>\n",
       "      <td>bsPG-1.3</td>\n",
       "      <td>RGGRLAYCRRRDCTCVGR</td>\n",
       "      <td>-----A-----D-T----</td>\n",
       "      <td>-0.65</td>\n",
       "      <td>4.651497</td>\n",
       "      <td>CP</td>\n",
       "      <td>&gt;64</td>\n",
       "      <td>-0.165692</td>\n",
       "      <td>NaN</td>\n",
       "      <td>-14.385390</td>\n",
       "      <td>-1.305665</td>\n",
       "      <td>100.0</td>\n",
       "      <td>-8.310135</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>PG1_3mut_1275003</td>\n",
       "      <td>bsPG-1.4</td>\n",
       "      <td>RGGRLDYCRRRFCVTTGR</td>\n",
       "      <td>-----D--------TT--</td>\n",
       "      <td>-0.56</td>\n",
       "      <td>4.742406</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>64</td>\n",
       "      <td>0.165692</td>\n",
       "      <td>1.025482</td>\n",
       "      <td>-19.078636</td>\n",
       "      <td>-0.686002</td>\n",
       "      <td>100.0</td>\n",
       "      <td>-2.867607</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>PG1_3mut_257802</td>\n",
       "      <td>bsPG-1.5</td>\n",
       "      <td>RGGRLQACRRRFCVTVGR</td>\n",
       "      <td>-----QA-------T---</td>\n",
       "      <td>-0.44</td>\n",
       "      <td>5.744660</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>8</td>\n",
       "      <td>0.721248</td>\n",
       "      <td>0.761174</td>\n",
       "      <td>-3.053714</td>\n",
       "      <td>-0.247956</td>\n",
       "      <td>100.0</td>\n",
       "      <td>-3.139629</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "                 ID       ID2            Sequence  RGGRLCYCRRRFCVCVGR  Select  \\\n",
       "0  PG1_3mut_1739000  bsPG-1.1  RGGRLQYCRRRFCVARGR  -----Q--------AR--   -0.82   \n",
       "1  PG1_3mut_1218602  bsPG-1.2  RGGRLQYCRRRGCVTVGR  -----Q-----G--T---   -0.76   \n",
       "2  PG1_3mut_1896424  bsPG-1.3  RGGRLAYCRRRDCTCVGR  -----A-----D-T----   -0.65   \n",
       "3  PG1_3mut_1275003  bsPG-1.4  RGGRLDYCRRRFCVTTGR  -----D--------TT--   -0.56   \n",
       "4   PG1_3mut_257802  bsPG-1.5  RGGRLQACRRRFCVTVGR  -----QA-------T---   -0.44   \n",
       "\n",
       "     Charge   group MIC MH     %hemo  L10Select  hemolysis_pred_v01.2  \\\n",
       "0  6.742145  <-0.25     16  0.428850   0.836425             -7.675692   \n",
       "1  5.742155  <-0.25      4  0.341131   0.134981            -14.298704   \n",
       "2  4.651497      CP    >64 -0.165692        NaN            -14.385390   \n",
       "3  4.742406  <-0.25     64  0.165692   1.025482            -19.078636   \n",
       "4  5.744660  <-0.25      8  0.721248   0.761174             -3.053714   \n",
       "\n",
       "   selectivity_pred_v01.2  activity_pred_v01.2  hemolysis_pred_v02  \n",
       "0               -0.987362                100.0           -4.054558  \n",
       "1               -1.215473                100.0           -6.763184  \n",
       "2               -1.305665                100.0           -8.310135  \n",
       "3               -0.686002                100.0           -2.867607  \n",
       "4               -0.247956                100.0           -3.139629  "
      ]
     },
     "execution_count": 35,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "meta_data['hemolysis_pred_v02'] = pred\n",
    "meta_data.head()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Selectivity"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 37,
   "metadata": {},
   "outputs": [],
   "source": [
    "# Loading the model\n",
    "model = joblib.load('models/model_v02_svmR20_esm2_15B_selectivity_regression.pkl')\n",
    "\n",
    "# Loading PCA weights\n",
    "pca = joblib.load('models/weights_pca20_v02_esm2_15B_selectivity.pkl')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 38,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "6"
      ]
     },
     "execution_count": 38,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "# calculates the probability of being active\n",
    "pred = model.predict(pca.transform(features))\n",
    "\n",
    "sum(pred < 0.5)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 39,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
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       "    .dataframe tbody tr th {\n",
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       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>ID</th>\n",
       "      <th>ID2</th>\n",
       "      <th>Sequence</th>\n",
       "      <th>RGGRLCYCRRRFCVCVGR</th>\n",
       "      <th>Select</th>\n",
       "      <th>Charge</th>\n",
       "      <th>group</th>\n",
       "      <th>MIC MH</th>\n",
       "      <th>%hemo</th>\n",
       "      <th>L10Select</th>\n",
       "      <th>hemolysis_pred_v01.2</th>\n",
       "      <th>selectivity_pred_v01.2</th>\n",
       "      <th>activity_pred_v01.2</th>\n",
       "      <th>hemolysis_pred_v02</th>\n",
       "      <th>selectivity_pred_v02</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>PG1_3mut_1739000</td>\n",
       "      <td>bsPG-1.1</td>\n",
       "      <td>RGGRLQYCRRRFCVARGR</td>\n",
       "      <td>-----Q--------AR--</td>\n",
       "      <td>-0.82</td>\n",
       "      <td>6.742145</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>16</td>\n",
       "      <td>0.428850</td>\n",
       "      <td>0.836425</td>\n",
       "      <td>-7.675692</td>\n",
       "      <td>-0.987362</td>\n",
       "      <td>100.0</td>\n",
       "      <td>-4.054558</td>\n",
       "      <td>0.448899</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>PG1_3mut_1218602</td>\n",
       "      <td>bsPG-1.2</td>\n",
       "      <td>RGGRLQYCRRRGCVTVGR</td>\n",
       "      <td>-----Q-----G--T---</td>\n",
       "      <td>-0.76</td>\n",
       "      <td>5.742155</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>4</td>\n",
       "      <td>0.341131</td>\n",
       "      <td>0.134981</td>\n",
       "      <td>-14.298704</td>\n",
       "      <td>-1.215473</td>\n",
       "      <td>100.0</td>\n",
       "      <td>-6.763184</td>\n",
       "      <td>0.368799</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>PG1_3mut_1896424</td>\n",
       "      <td>bsPG-1.3</td>\n",
       "      <td>RGGRLAYCRRRDCTCVGR</td>\n",
       "      <td>-----A-----D-T----</td>\n",
       "      <td>-0.65</td>\n",
       "      <td>4.651497</td>\n",
       "      <td>CP</td>\n",
       "      <td>&gt;64</td>\n",
       "      <td>-0.165692</td>\n",
       "      <td>NaN</td>\n",
       "      <td>-14.385390</td>\n",
       "      <td>-1.305665</td>\n",
       "      <td>100.0</td>\n",
       "      <td>-8.310135</td>\n",
       "      <td>0.390410</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>PG1_3mut_1275003</td>\n",
       "      <td>bsPG-1.4</td>\n",
       "      <td>RGGRLDYCRRRFCVTTGR</td>\n",
       "      <td>-----D--------TT--</td>\n",
       "      <td>-0.56</td>\n",
       "      <td>4.742406</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>64</td>\n",
       "      <td>0.165692</td>\n",
       "      <td>1.025482</td>\n",
       "      <td>-19.078636</td>\n",
       "      <td>-0.686002</td>\n",
       "      <td>100.0</td>\n",
       "      <td>-2.867607</td>\n",
       "      <td>0.552553</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>PG1_3mut_257802</td>\n",
       "      <td>bsPG-1.5</td>\n",
       "      <td>RGGRLQACRRRFCVTVGR</td>\n",
       "      <td>-----QA-------T---</td>\n",
       "      <td>-0.44</td>\n",
       "      <td>5.744660</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>8</td>\n",
       "      <td>0.721248</td>\n",
       "      <td>0.761174</td>\n",
       "      <td>-3.053714</td>\n",
       "      <td>-0.247956</td>\n",
       "      <td>100.0</td>\n",
       "      <td>-3.139629</td>\n",
       "      <td>0.636513</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "                 ID       ID2            Sequence  RGGRLCYCRRRFCVCVGR  Select  \\\n",
       "0  PG1_3mut_1739000  bsPG-1.1  RGGRLQYCRRRFCVARGR  -----Q--------AR--   -0.82   \n",
       "1  PG1_3mut_1218602  bsPG-1.2  RGGRLQYCRRRGCVTVGR  -----Q-----G--T---   -0.76   \n",
       "2  PG1_3mut_1896424  bsPG-1.3  RGGRLAYCRRRDCTCVGR  -----A-----D-T----   -0.65   \n",
       "3  PG1_3mut_1275003  bsPG-1.4  RGGRLDYCRRRFCVTTGR  -----D--------TT--   -0.56   \n",
       "4   PG1_3mut_257802  bsPG-1.5  RGGRLQACRRRFCVTVGR  -----QA-------T---   -0.44   \n",
       "\n",
       "     Charge   group MIC MH     %hemo  L10Select  hemolysis_pred_v01.2  \\\n",
       "0  6.742145  <-0.25     16  0.428850   0.836425             -7.675692   \n",
       "1  5.742155  <-0.25      4  0.341131   0.134981            -14.298704   \n",
       "2  4.651497      CP    >64 -0.165692        NaN            -14.385390   \n",
       "3  4.742406  <-0.25     64  0.165692   1.025482            -19.078636   \n",
       "4  5.744660  <-0.25      8  0.721248   0.761174             -3.053714   \n",
       "\n",
       "   selectivity_pred_v01.2  activity_pred_v01.2  hemolysis_pred_v02  \\\n",
       "0               -0.987362                100.0           -4.054558   \n",
       "1               -1.215473                100.0           -6.763184   \n",
       "2               -1.305665                100.0           -8.310135   \n",
       "3               -0.686002                100.0           -2.867607   \n",
       "4               -0.247956                100.0           -3.139629   \n",
       "\n",
       "   selectivity_pred_v02  \n",
       "0              0.448899  \n",
       "1              0.368799  \n",
       "2              0.390410  \n",
       "3              0.552553  \n",
       "4              0.636513  "
      ]
     },
     "execution_count": 39,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "meta_data['selectivity_pred_v02'] = pred\n",
    "meta_data.head()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Activity"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 40,
   "metadata": {},
   "outputs": [],
   "source": [
    "# Loading the model\n",
    "model = joblib.load('models/model_v02_GNB15_esm2_15B_activity_classification.pkl')\n",
    "\n",
    "# Loading PCA weights\n",
    "pca = joblib.load('models/weights_pca15_v02_esm2_15B_activity.pkl')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 41,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "21"
      ]
     },
     "execution_count": 41,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "# calculates the probability of being active\n",
    "prob = model.predict_proba(pca.transform(features))\n",
    "pred = (prob[:, 1] * 100).round(2)\n",
    "\n",
    "sum(pred > 90)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 42,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
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       "\n",
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       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>ID</th>\n",
       "      <th>ID2</th>\n",
       "      <th>Sequence</th>\n",
       "      <th>RGGRLCYCRRRFCVCVGR</th>\n",
       "      <th>Select</th>\n",
       "      <th>Charge</th>\n",
       "      <th>group</th>\n",
       "      <th>MIC MH</th>\n",
       "      <th>%hemo</th>\n",
       "      <th>L10Select</th>\n",
       "      <th>hemolysis_pred_v01.2</th>\n",
       "      <th>selectivity_pred_v01.2</th>\n",
       "      <th>activity_pred_v01.2</th>\n",
       "      <th>hemolysis_pred_v02</th>\n",
       "      <th>selectivity_pred_v02</th>\n",
       "      <th>activity_pred_v02</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>PG1_3mut_1739000</td>\n",
       "      <td>bsPG-1.1</td>\n",
       "      <td>RGGRLQYCRRRFCVARGR</td>\n",
       "      <td>-----Q--------AR--</td>\n",
       "      <td>-0.82</td>\n",
       "      <td>6.742145</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>16</td>\n",
       "      <td>0.428850</td>\n",
       "      <td>0.836425</td>\n",
       "      <td>-7.675692</td>\n",
       "      <td>-0.987362</td>\n",
       "      <td>100.0</td>\n",
       "      <td>-4.054558</td>\n",
       "      <td>0.448899</td>\n",
       "      <td>92.34</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>PG1_3mut_1218602</td>\n",
       "      <td>bsPG-1.2</td>\n",
       "      <td>RGGRLQYCRRRGCVTVGR</td>\n",
       "      <td>-----Q-----G--T---</td>\n",
       "      <td>-0.76</td>\n",
       "      <td>5.742155</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>4</td>\n",
       "      <td>0.341131</td>\n",
       "      <td>0.134981</td>\n",
       "      <td>-14.298704</td>\n",
       "      <td>-1.215473</td>\n",
       "      <td>100.0</td>\n",
       "      <td>-6.763184</td>\n",
       "      <td>0.368799</td>\n",
       "      <td>88.34</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>PG1_3mut_1896424</td>\n",
       "      <td>bsPG-1.3</td>\n",
       "      <td>RGGRLAYCRRRDCTCVGR</td>\n",
       "      <td>-----A-----D-T----</td>\n",
       "      <td>-0.65</td>\n",
       "      <td>4.651497</td>\n",
       "      <td>CP</td>\n",
       "      <td>&gt;64</td>\n",
       "      <td>-0.165692</td>\n",
       "      <td>NaN</td>\n",
       "      <td>-14.385390</td>\n",
       "      <td>-1.305665</td>\n",
       "      <td>100.0</td>\n",
       "      <td>-8.310135</td>\n",
       "      <td>0.390410</td>\n",
       "      <td>95.37</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>PG1_3mut_1275003</td>\n",
       "      <td>bsPG-1.4</td>\n",
       "      <td>RGGRLDYCRRRFCVTTGR</td>\n",
       "      <td>-----D--------TT--</td>\n",
       "      <td>-0.56</td>\n",
       "      <td>4.742406</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>64</td>\n",
       "      <td>0.165692</td>\n",
       "      <td>1.025482</td>\n",
       "      <td>-19.078636</td>\n",
       "      <td>-0.686002</td>\n",
       "      <td>100.0</td>\n",
       "      <td>-2.867607</td>\n",
       "      <td>0.552553</td>\n",
       "      <td>90.87</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>PG1_3mut_257802</td>\n",
       "      <td>bsPG-1.5</td>\n",
       "      <td>RGGRLQACRRRFCVTVGR</td>\n",
       "      <td>-----QA-------T---</td>\n",
       "      <td>-0.44</td>\n",
       "      <td>5.744660</td>\n",
       "      <td>&lt;-0.25</td>\n",
       "      <td>8</td>\n",
       "      <td>0.721248</td>\n",
       "      <td>0.761174</td>\n",
       "      <td>-3.053714</td>\n",
       "      <td>-0.247956</td>\n",
       "      <td>100.0</td>\n",
       "      <td>-3.139629</td>\n",
       "      <td>0.636513</td>\n",
       "      <td>94.94</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "                 ID       ID2            Sequence  RGGRLCYCRRRFCVCVGR  Select  \\\n",
       "0  PG1_3mut_1739000  bsPG-1.1  RGGRLQYCRRRFCVARGR  -----Q--------AR--   -0.82   \n",
       "1  PG1_3mut_1218602  bsPG-1.2  RGGRLQYCRRRGCVTVGR  -----Q-----G--T---   -0.76   \n",
       "2  PG1_3mut_1896424  bsPG-1.3  RGGRLAYCRRRDCTCVGR  -----A-----D-T----   -0.65   \n",
       "3  PG1_3mut_1275003  bsPG-1.4  RGGRLDYCRRRFCVTTGR  -----D--------TT--   -0.56   \n",
       "4   PG1_3mut_257802  bsPG-1.5  RGGRLQACRRRFCVTVGR  -----QA-------T---   -0.44   \n",
       "\n",
       "     Charge   group MIC MH     %hemo  L10Select  hemolysis_pred_v01.2  \\\n",
       "0  6.742145  <-0.25     16  0.428850   0.836425             -7.675692   \n",
       "1  5.742155  <-0.25      4  0.341131   0.134981            -14.298704   \n",
       "2  4.651497      CP    >64 -0.165692        NaN            -14.385390   \n",
       "3  4.742406  <-0.25     64  0.165692   1.025482            -19.078636   \n",
       "4  5.744660  <-0.25      8  0.721248   0.761174             -3.053714   \n",
       "\n",
       "   selectivity_pred_v01.2  activity_pred_v01.2  hemolysis_pred_v02  \\\n",
       "0               -0.987362                100.0           -4.054558   \n",
       "1               -1.215473                100.0           -6.763184   \n",
       "2               -1.305665                100.0           -8.310135   \n",
       "3               -0.686002                100.0           -2.867607   \n",
       "4               -0.247956                100.0           -3.139629   \n",
       "\n",
       "   selectivity_pred_v02  activity_pred_v02  \n",
       "0              0.448899              92.34  \n",
       "1              0.368799              88.34  \n",
       "2              0.390410              95.37  \n",
       "3              0.552553              90.87  \n",
       "4              0.636513              94.94  "
      ]
     },
     "execution_count": 42,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "meta_data['activity_pred_v02'] = pred\n",
    "meta_data.head()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# Overall Performance V1 x V2"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 43,
   "metadata": {},
   "outputs": [],
   "source": [
    "meta_data['MIC'] = [convert_mic(x) for x in meta_data['MIC MH']]\n",
    "meta_data['L10Select'].fillna(100, inplace=True)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 45,
   "metadata": {},
   "outputs": [],
   "source": [
    "# true values\n",
    "true_act = [1 if x<=8 else 0 for x in meta_data['MIC']]\n",
    "true_hemo = [1 if x<=2 else 0 for x in meta_data['%hemo']]\n",
    "true_sel = [1 if x<0.5 else 0 for x in meta_data['L10Select']]\n",
    "\n",
    "pred_v01_act = [1 if x<=8 else 0 for x in meta_data['activity_pred_v01.2']]\n",
    "pred_v01_hemo = [1 if x<=2 else 0 for x in meta_data['hemolysis_pred_v01.2']]\n",
    "pred_v01_sel = [1 if x<0.5 else 0 for x in meta_data['selectivity_pred_v01.2']]\n",
    "\n",
    "pred_v02_act = [1 if x<=8 else 0 for x in meta_data['activity_pred_v02']]\n",
    "pred_v02_hemo = [1 if x<=2 else 0 for x in meta_data['hemolysis_pred_v02']]\n",
    "pred_v02_sel = [1 if x<0.5 else 0 for x in meta_data['selectivity_pred_v02']]"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 46,
   "metadata": {},
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/stor/work/Wilke/luiz/DMS_ML_AMP/venv/lib/python3.8/site-packages/sklearn/metrics/_classification.py:1344: UndefinedMetricWarning: Precision is ill-defined and being set to 0.0 due to no predicted samples. Use `zero_division` parameter to control this behavior.\n",
      "  _warn_prf(average, modifier, msg_start, len(result))\n"
     ]
    },
    {
     "data": {
      "text/html": [
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       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>Version</th>\n",
       "      <th>Feature</th>\n",
       "      <th>Accuracy</th>\n",
       "      <th>Recall</th>\n",
       "      <th>Precision</th>\n",
       "      <th>F1 Score</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>V01</td>\n",
       "      <td>Activity</td>\n",
       "      <td>0.750000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>V01</td>\n",
       "      <td>Hemolysis</td>\n",
       "      <td>0.888889</td>\n",
       "      <td>1.000000</td>\n",
       "      <td>0.888889</td>\n",
       "      <td>0.941176</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>V01</td>\n",
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      ],
      "text/plain": [
       "  Version      Feature  Accuracy    Recall  Precision  F1 Score\n",
       "0     V01     Activity  0.750000  0.000000   0.000000  0.000000\n",
       "0     V01    Hemolysis  0.888889  1.000000   0.888889  0.941176\n",
       "0     V01  Selectivity  0.222222  0.833333   0.156250  0.263158"
      ]
     },
     "execution_count": 46,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "df = pd.DataFrame()\n",
    "\n",
    "# version 1\n",
    "accuracy = metrics.accuracy_score(true_act, pred_v01_act)\n",
    "recall = metrics.recall_score(true_act, pred_v01_act)\n",
    "precision = metrics.precision_score(true_act, pred_v01_act)\n",
    "f1_score = metrics.f1_score(true_act, pred_v01_act)\n",
    "\n",
    "df_dict={'Version': 'V01', 'Feature': 'Activity', 'Accuracy': accuracy, 'Recall': recall, 'Precision': precision, 'F1 Score': f1_score}\n",
    "df = pd.concat([df, pd.DataFrame(df_dict, index=[0])])\n",
    "\n",
    "# version 1\n",
    "accuracy = metrics.accuracy_score(true_hemo, pred_v01_hemo)\n",
    "recall = metrics.recall_score(true_hemo, pred_v01_hemo)\n",
    "precision = metrics.precision_score(true_hemo, pred_v01_hemo)\n",
    "f1_score = metrics.f1_score(true_hemo, pred_v01_hemo)\n",
    "\n",
    "df_dict={'Version': 'V01', 'Feature': 'Hemolysis', 'Accuracy': accuracy, 'Recall': recall, 'Precision': precision, 'F1 Score': f1_score}\n",
    "df = pd.concat([df, pd.DataFrame(df_dict, index=[0])])\n",
    "\n",
    "# version 1\n",
    "accuracy = metrics.accuracy_score(true_sel, pred_v01_sel)\n",
    "recall = metrics.recall_score(true_sel, pred_v01_sel)\n",
    "precision = metrics.precision_score(true_sel, pred_v01_sel)\n",
    "f1_score = metrics.f1_score(true_sel, pred_v01_sel)\n",
    "\n",
    "df_dict={'Version': 'V01', 'Feature': 'Selectivity', 'Accuracy': accuracy, 'Recall': recall, 'Precision': precision, 'F1 Score': f1_score}\n",
    "df = pd.concat([df, pd.DataFrame(df_dict, index=[0])])\n",
    "\n",
    "df"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 47,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
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       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>Version</th>\n",
       "      <th>Feature</th>\n",
       "      <th>Accuracy</th>\n",
       "      <th>Recall</th>\n",
       "      <th>Precision</th>\n",
       "      <th>F1 Score</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>V01</td>\n",
       "      <td>Activity</td>\n",
       "      <td>0.750000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>V01</td>\n",
       "      <td>Hemolysis</td>\n",
       "      <td>0.888889</td>\n",
       "      <td>1.000000</td>\n",
       "      <td>0.888889</td>\n",
       "      <td>0.941176</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>V01</td>\n",
       "      <td>Selectivity</td>\n",
       "      <td>0.222222</td>\n",
       "      <td>0.833333</td>\n",
       "      <td>0.156250</td>\n",
       "      <td>0.263158</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>V02</td>\n",
       "      <td>Activity</td>\n",
       "      <td>0.750000</td>\n",
       "      <td>0.111111</td>\n",
       "      <td>0.500000</td>\n",
       "      <td>0.181818</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>V02</td>\n",
       "      <td>Hemolysis</td>\n",
       "      <td>0.861111</td>\n",
       "      <td>0.906250</td>\n",
       "      <td>0.935484</td>\n",
       "      <td>0.920635</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>V02</td>\n",
       "      <td>Selectivity</td>\n",
       "      <td>0.777778</td>\n",
       "      <td>0.333333</td>\n",
       "      <td>0.333333</td>\n",
       "      <td>0.333333</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "  Version      Feature  Accuracy    Recall  Precision  F1 Score\n",
       "0     V01     Activity  0.750000  0.000000   0.000000  0.000000\n",
       "0     V01    Hemolysis  0.888889  1.000000   0.888889  0.941176\n",
       "0     V01  Selectivity  0.222222  0.833333   0.156250  0.263158\n",
       "0     V02     Activity  0.750000  0.111111   0.500000  0.181818\n",
       "0     V02    Hemolysis  0.861111  0.906250   0.935484  0.920635\n",
       "0     V02  Selectivity  0.777778  0.333333   0.333333  0.333333"
      ]
     },
     "execution_count": 47,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "# version 2\n",
    "accuracy = metrics.accuracy_score(true_act, pred_v02_act)\n",
    "recall = metrics.recall_score(true_act, pred_v02_act)\n",
    "precision = metrics.precision_score(true_act, pred_v02_act)\n",
    "f1_score = metrics.f1_score(true_act, pred_v02_act)\n",
    "\n",
    "df_dict={'Version': 'V02', 'Feature': 'Activity', 'Accuracy': accuracy, 'Recall': recall, 'Precision': precision, 'F1 Score': f1_score}\n",
    "df = pd.concat([df, pd.DataFrame(df_dict, index=[0])])\n",
    "\n",
    "# version 2\n",
    "accuracy = metrics.accuracy_score(true_hemo, pred_v02_hemo)\n",
    "recall = metrics.recall_score(true_hemo, pred_v02_hemo)\n",
    "precision = metrics.precision_score(true_hemo, pred_v02_hemo)\n",
    "f1_score = metrics.f1_score(true_hemo, pred_v02_hemo)\n",
    "\n",
    "df_dict={'Version': 'V02', 'Feature': 'Hemolysis', 'Accuracy': accuracy, 'Recall': recall, 'Precision': precision, 'F1 Score': f1_score}\n",
    "df = pd.concat([df, pd.DataFrame(df_dict, index=[0])])\n",
    "\n",
    "# version 2\n",
    "accuracy = metrics.accuracy_score(true_sel, pred_v02_sel)\n",
    "recall = metrics.recall_score(true_sel, pred_v02_sel)\n",
    "precision = metrics.precision_score(true_sel, pred_v02_sel)\n",
    "f1_score = metrics.f1_score(true_sel, pred_v02_sel)\n",
    "\n",
    "df_dict={'Version': 'V02', 'Feature': 'Selectivity', 'Accuracy': accuracy, 'Recall': recall, 'Precision': precision, 'F1 Score': f1_score}\n",
    "df = pd.concat([df, pd.DataFrame(df_dict, index=[0])])\n",
    "\n",
    "df"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 48,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
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       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>Version</th>\n",
       "      <th>Feature</th>\n",
       "      <th>Metric</th>\n",
       "      <th>Score</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>V01</td>\n",
       "      <td>Activity</td>\n",
       "      <td>Accuracy</td>\n",
       "      <td>0.750000</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>V01</td>\n",
       "      <td>Activity</td>\n",
       "      <td>F1 Score</td>\n",
       "      <td>0.000000</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>V01</td>\n",
       "      <td>Activity</td>\n",
       "      <td>Precision</td>\n",
       "      <td>0.000000</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>V01</td>\n",
       "      <td>Activity</td>\n",
       "      <td>Recall</td>\n",
       "      <td>0.000000</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>V01</td>\n",
       "      <td>Hemolysis</td>\n",
       "      <td>Accuracy</td>\n",
       "      <td>0.888889</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5</th>\n",
       "      <td>V01</td>\n",
       "      <td>Hemolysis</td>\n",
       "      <td>F1 Score</td>\n",
       "      <td>0.941176</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6</th>\n",
       "      <td>V01</td>\n",
       "      <td>Hemolysis</td>\n",
       "      <td>Precision</td>\n",
       "      <td>0.888889</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>7</th>\n",
       "      <td>V01</td>\n",
       "      <td>Hemolysis</td>\n",
       "      <td>Recall</td>\n",
       "      <td>1.000000</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>8</th>\n",
       "      <td>V01</td>\n",
       "      <td>Selectivity</td>\n",
       "      <td>Accuracy</td>\n",
       "      <td>0.222222</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>9</th>\n",
       "      <td>V01</td>\n",
       "      <td>Selectivity</td>\n",
       "      <td>F1 Score</td>\n",
       "      <td>0.263158</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>V01</td>\n",
       "      <td>Selectivity</td>\n",
       "      <td>Precision</td>\n",
       "      <td>0.156250</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>11</th>\n",
       "      <td>V01</td>\n",
       "      <td>Selectivity</td>\n",
       "      <td>Recall</td>\n",
       "      <td>0.833333</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12</th>\n",
       "      <td>V02</td>\n",
       "      <td>Activity</td>\n",
       "      <td>Accuracy</td>\n",
       "      <td>0.750000</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13</th>\n",
       "      <td>V02</td>\n",
       "      <td>Activity</td>\n",
       "      <td>F1 Score</td>\n",
       "      <td>0.181818</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14</th>\n",
       "      <td>V02</td>\n",
       "      <td>Activity</td>\n",
       "      <td>Precision</td>\n",
       "      <td>0.500000</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15</th>\n",
       "      <td>V02</td>\n",
       "      <td>Activity</td>\n",
       "      <td>Recall</td>\n",
       "      <td>0.111111</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16</th>\n",
       "      <td>V02</td>\n",
       "      <td>Hemolysis</td>\n",
       "      <td>Accuracy</td>\n",
       "      <td>0.861111</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17</th>\n",
       "      <td>V02</td>\n",
       "      <td>Hemolysis</td>\n",
       "      <td>F1 Score</td>\n",
       "      <td>0.920635</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>18</th>\n",
       "      <td>V02</td>\n",
       "      <td>Hemolysis</td>\n",
       "      <td>Precision</td>\n",
       "      <td>0.935484</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19</th>\n",
       "      <td>V02</td>\n",
       "      <td>Hemolysis</td>\n",
       "      <td>Recall</td>\n",
       "      <td>0.906250</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>20</th>\n",
       "      <td>V02</td>\n",
       "      <td>Selectivity</td>\n",
       "      <td>Accuracy</td>\n",
       "      <td>0.777778</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21</th>\n",
       "      <td>V02</td>\n",
       "      <td>Selectivity</td>\n",
       "      <td>F1 Score</td>\n",
       "      <td>0.333333</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>22</th>\n",
       "      <td>V02</td>\n",
       "      <td>Selectivity</td>\n",
       "      <td>Precision</td>\n",
       "      <td>0.333333</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23</th>\n",
       "      <td>V02</td>\n",
       "      <td>Selectivity</td>\n",
       "      <td>Recall</td>\n",
       "      <td>0.333333</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "   Version      Feature     Metric     Score\n",
       "0      V01     Activity   Accuracy  0.750000\n",
       "1      V01     Activity   F1 Score  0.000000\n",
       "2      V01     Activity  Precision  0.000000\n",
       "3      V01     Activity     Recall  0.000000\n",
       "4      V01    Hemolysis   Accuracy  0.888889\n",
       "5      V01    Hemolysis   F1 Score  0.941176\n",
       "6      V01    Hemolysis  Precision  0.888889\n",
       "7      V01    Hemolysis     Recall  1.000000\n",
       "8      V01  Selectivity   Accuracy  0.222222\n",
       "9      V01  Selectivity   F1 Score  0.263158\n",
       "10     V01  Selectivity  Precision  0.156250\n",
       "11     V01  Selectivity     Recall  0.833333\n",
       "12     V02     Activity   Accuracy  0.750000\n",
       "13     V02     Activity   F1 Score  0.181818\n",
       "14     V02     Activity  Precision  0.500000\n",
       "15     V02     Activity     Recall  0.111111\n",
       "16     V02    Hemolysis   Accuracy  0.861111\n",
       "17     V02    Hemolysis   F1 Score  0.920635\n",
       "18     V02    Hemolysis  Precision  0.935484\n",
       "19     V02    Hemolysis     Recall  0.906250\n",
       "20     V02  Selectivity   Accuracy  0.777778\n",
       "21     V02  Selectivity   F1 Score  0.333333\n",
       "22     V02  Selectivity  Precision  0.333333\n",
       "23     V02  Selectivity     Recall  0.333333"
      ]
     },
     "execution_count": 48,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "# id_vars: Columns that should remain unaltered.\n",
    "# value_vars: Columns that you want to melt (i.e., unpivot). These columns will be transformed from wide format to long format.\n",
    "# var_name: Name of the new column that will store the melted columns' names (default is 'variable').\n",
    "# value_name: Name of the new column that will store the values (default is 'value').\n",
    "\n",
    "df_melted = pd.melt(df, \n",
    "        id_vars=['Version', 'Feature'],\n",
    "        value_vars=['Accuracy', 'Recall', 'Precision', 'F1 Score'],\n",
    "        var_name='Metric',\n",
    "        value_name='Score')\n",
    "\n",
    "df_melted= df_melted.sort_values(by=['Version', 'Feature', 'Metric']).reset_index(drop=True)\n",
    "df_melted"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 50,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": 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fqaeeeuo7x7777ruF3/72t4Uf//jHhfr16xcaNmxY2GKLLQp//vOfCzNmzChMmzatULdu3cIvfvGLxZ7j888/LzRs2LCw9957V+dlAEVKn6RPgtpKjwTUJD2SHglqM30SsDyVFAqV/FwMAAAAAAAAgFrJM3kBAAAAAAAAioiQFwAAAAAAAKCICHkBAAAAAAAAioiQFwAAAAAAAKCICHkBAAAAAAAAioiQFwAAAAAAAKCICHkBAAAAAAAAioiQFwAAAAAAAKCICHkBAAAAAAAAioiQF76hXbt2KSkp+dbXeeedV9Nl/mC89957+b//+7906tQpK6+8curVq5dWrVpls802y6BBgzJy5MjMnz+/WuZa+P+/2uqNN95ISUlJ2rVrV9OlfKuv/7Pw17/+9VvHHnnkkeVj11lnneVUYdK/f/+UlJRk5MiRy23Ob7PDDjukpKQkEyZMqOlSAL43PdLypUf6//RI1UePBLBs6JOWL33S/6dPqj76JKAY1a3pAqC26tat22IbiQ033HA5V/NV09a+ffu0bds2b7zxxnKff1l49NFH06tXr3zyySdp3LhxunTpkhYtWuSzzz7Lc889lyuuuCJXXHFFevfuncaNG9d0uVXWrl27vPnmm5kyZUqtb76X1IgRI/Lb3/620n2zZ8/O6NGjq33OCRMmpHv37tl+++01ugA1QI+07OmRip8eCWDFpE9a9vRJxU+fBFB9hLywGAMHDkz//v1ruowfrDlz5mS//fbLJ598kgMPPDAXX3xxmjRpUmHMyy+/nCuvvDJ16tSpoSqXr9atW+ell17KSiutVNOlLJHOnTvn6aefzlNPPZUtt9xykf233HJLPvnkk2y55ZZ56qmnaqBCAJYFPdKypUdalB4JgGKhT1q29EmL0icBrNgs1wzUiIcffjjvvPNO6tatm8suu2yRpjxJ1l9//Zx11llp0KBBDVS4/K200kpZf/3106FDh5ouZYkccsghSZIrr7yy0v3Dhw+vMA4A+G56pEXpkQCARJ9UGX0SwIpNyAvV4JlnnslBBx2UtdZaK2VlZWnevHl69uyZu+66q9LxL774Yk499dR069YtrVu3Tr169bLqqqumR48eueGGGxYZ379//7Rv3z5J8uabby7yXJevj/u2Z0eMHDkyJSUli/yq9OvbP/744/zmN79Jhw4dUlZWlh122KHC2LFjx2afffbJmmuumXr16mWNNdbI3nvvnccee2zJ37Ak06ZNS5I0btw4jRo1WqpjF7rpppuyyy67ZPXVV0+9evXSunXrHHzwwXnxxReX+lzz5s3LFVdckR122CHNmzdPWVlZ2rdvn8MPPzxTp05d7HHv/L/27j0oyuoPA/gDsssabGIgN5VVLqKjFQTkBYkICzQVAkWUKS6WNTmOjfe8dNduU42mqZltl8lR0SiYvDXGOpWVdjNSyTIChNIAFaQFEb6/P5x95XV3YQHtJ/Z8ZpzRc95z3vOed3d8ds4776mowPz583HzzTdDr9fDzc0NgwYNQlZWFvbv3w/g0vyWlpYCAAYOHKi6f5bXxLS3j8qJEycwa9YshISEQKfToVevXoiOjsb69ett7jXT+r7W19fj8ccfR3BwMFxdXeHr64vMzExUVFR0eK4sxo4dC19fX2zevBkNDQ2qupKSEhQWFmLkyJEYPHhwm/2YzWa88sorGDFiBDw8PKDT6RAaGooFCxagurpadeydd96JuLg4AMC+fftU82hv3kpKSnD//ffD19cXrq6uCAoKwtKlS9HY2Gh3TJs3b0Z8fLzyWTAYDMjJycGxY8fstikvL0dOTg78/Pyg0+kQEhKCJUuWwGw2t3n9RETXM2YkZiRmJGYkZiQiItuYk5iTmJOYk5iTiKir+Lpmoi5auXIl5syZg5aWFoSFhWH48OH466+/YDKZsGfPHjz99NN44oknVG1effVVbNy4EYMHD8bNN98MDw8PlJWVobCwEHv37sXXX3+NV199VTl+9OjROHfuHLZv3w43NzdMmjTpqlxLVVUVIiMjcebMGcTExCAiIgJarVapnzdvHl555RU4OzsjMjISMTExKCsrw8cff4yCggJs2LAB2dnZDp0rICAAAHDmzBm88847HXqd0YULF5CRkYGtW7fC1dUVERER6Nu3L44dO4YPPvgAH374IT788EMkJiY61F9dXR0mTpwIk8kEd3d3REREoE+fPigqKsK6deuQm5uLTz/9FOHh4ap2e/fuxaRJk3DmzBl4e3sjPj4eWq0Wf/zxh7J/yKhRoxAcHIzMzExs27YN9fX1SE1NVe0L4+vr2+4YDx48iMTERNTU1CAgIADJyck4e/YsTCYT9u/fj7y8POTn56vul8XZs2cxatQolJWVISYmBsOGDcNXX32F9957D/v27cOhQ4fQq1cvh+aqNRcXFzzwwAN46aWXsH37dmRkZCh1RqMRItLuk5eVlZVITExEUVERbrrpJkRFRUGv1+P777/Hyy+/jNzcXJhMJhgMBgBAYmIidDoddu/eDR8fH9U99vLysur/xx9/xOzZs9G7d2/ExsaipqYGX375JZYvX47Dhw8jLy9PdbyIICsrC++99x5cXFxwxx13wNvbG99//z2MRiO2bNmC7du3W322iouLERsbi1OnTsHPzw8TJ05EfX09XnvtNRQWFnZ4bomIrgfMSMxIzEjMSMxIRES2MScxJzEnMScxJxHRFSFEpGIwGASAGI3Gdo/dtWuXODk5iZeXl+zbt09V99NPP0m/fv0EgJhMJlWdyWSS48ePW/VXXFystPnmm29UdSUlJQJADAaD3fFkZma2OXaj0SgAJDMz02Y5AImPj5ezZ89atX3zzTcFgAQHB8uhQ4dUdfv27RO9Xi9arVaOHTtmd3ytNTc3S3h4uHLeqKgoWbJkieTl5Ul5eXmbbRcvXiwAZPjw4fL777+r6nJzc6VHjx7Su3dvOX36tKrOcq7LTZs2TQDI+PHj5eTJk6q61157TQBISEiIXLhwQSkvKyuTXr16CQBZtGiRNDY2qtqdPHlSPv/8c1WZ5bNVUlJi87rs3eOGhgal7SOPPCLnz59X6o4fPy4DBgwQALJ48WJVu9b3NSEhQXVfa2pqJCwsTADIihUrbI7HHkuf5eXlUlxcLADkrrvuUuqbm5slICBA3NzcpLa2VgoLCwWABAUFqfppaWmR6OhoASDTp0+X2tpapa6pqUnmzp0rACQuLk7VztJfbGys3TFavgsAZMmSJap7V1RUJG5ubgJA9u/fr2q3du1aASBeXl7yww8/qMb65JNPCgDx8PCQU6dOqdpFRUUJAElLSxOz2ayUl5aWSlBQkDKWwsJCu2MmIrrWMSMxI7XGjGSNGYkZiYj+u5iTmJNaY06yxpzEnEREVwcXeYkuYwlA9v60DgPDhw8XALJt2zabfW3dulUASGpqqsPnX79+vQCQ+fPnq8r/jWCu0Whs/mBobm4Wf39/ASDffvutzb5feuklASBz585t8/paq6yslLFjx9qc50GDBskLL7wg//zzj6pNdXW19OzZU3Q6nZw4ccJmv48++qgAkNdff11VbiuYHzlyRJycnMTf318VDFsbN26cAJCCggKl7LHHHhMAMmHCBIevt7PB/P333xcA4u/vLw0NDVbttm3bJgBEr9erQqHlvrq5uUllZaVVu82bN1uFake0DuYiItHR0eLk5KRc165duwSAZGVliYjYDeY7d+4UABIWFiZNTU1W52lubpZhw4YJACkqKlLKOxLMIyIipKWlxar+kUceEQDyzDPPqMotIXrVqlVWbVpaWuSWW24RALJ8+XKl/IsvvlDmuaqqyqpdXl4egzkRXReYkZiRLseMpMaMxIxERP9dzEnMSZdjTlJjTmJOIqKrg3vyEtkRHR2NzMxMqz+WV2tUVVXhwIED6NmzJyZMmGCzD8seJJb9NFo7d+4ccnNzsXjxYsyYMQNZWVnIysrC9u3bAQC//PLL1bmwNoSHhyMwMNCq/IcffkBlZSWCgoIQERFhs21b12qPn58fduzYgZ9//hkrVqzAhAkT0LdvXwDAsWPHsGjRIowcORJnzpxR2hQWFsJsNit70HR1LDt27ICIYOzYsdDr9Q73t2vXLgDAjBkz2j1HV1n2WUlPT4erq6tVfUpKCnr37o26ujp89913VvWRkZHw8/OzKh8yZAgAdGkvFQDIycmBiMBoNAIA3n77baW8LZ988gkAIDU1FS4u1rsHODs744477gDQsc9Va+PHj1ftNWRh69pPnDiB48ePAwAyMzOt2jg5OSmvkGr92hzL/UlMTISnp6dVu6SkpE69woiI6FrFjHQJM5J1f8xIlzAjmQAwIxHRfwtz0iXMSdb9MSddwpxkAsCcRERdxz15iex48MEH29zbo6SkBCICs9lsMyy19vfff6v+XVBQgOzsbFRXV9ttU1tb26HxXgkDBgywWf77778DAI4fP24z5LR2+bU6YujQoRg6dKjy76NHj+KNN97AmjVrcOjQISxZsgRr1qxRjWXv3r1XZCyW/jZu3IiNGzc63F9paSkAYPDgwe2eo6ss4XHgwIE2652cnDBw4ECcPn3aZsi27FlzuRtvvBEA0NDQ0KXxpaWlYfbs2Xj33Xcxa9YsfPzxxwgJCUFMTEyb7Sxzv2zZMixbtqzNYzvzuQI6du2WufP09FTqLxcUFKQ6FrgY6IG278+AAQNw6NChDo6eiOjaxIx0CTOSdX/MSJcwIzEjEdF/D3PSJcxJ1v0xJ13CnMScRERXBhd5iTqppaUFAODu7o7U1FSH21VUVGDKlCkwm81YsGABMjIyMGDAALi7u8PZ2Rl79uxBQkICROSqjdmenj17ttnO19cXCQkJbfbh5eXVucG1MmTIELz++utwdnbGqlWr8NFHHynB3DKW4OBgREdHt9mPI6HZ0l9YWBhuvfXWNo8dPny4I8O/5jg7X92XNri7u2Py5MkwGo3IyclBY2Oj8pRiWyxzP3r0aCXw2tP6h1tHXO1rJyIia8xItjEjXXuYkYiI6N/GnGQbc9K1hzmJiKh74CIvUSf1798fwMUnq95++22HA0BBQQHMZjPuu+8+vPjii1b1v/76a6fHpNVqAQB1dXU26y1PDHaU5Vo9PT3xzjvvdKqPzrjnnnuwatUqVFVVWY0lNDT0iozF0l90dDRWr17tcLuAgAD88ssvKC4uRnBwcJfH0RbLq4QsTyvaUlJSojr235aTkwOj0YiCggL06NHD5itqLmeZ+6SkJMybN+9qD7Fdlrmrrq5GbW2tzScwLfeg9Txb/v7HH3/Y7buz3z0iou6IGenqY0a6iBnp38GMRER05TAnXX3MSRcxJ/07mJOI6P+Nj6UQdZK/vz9uueUW1NXVKXtqOKKmpgYAYDAYrOpEBJs2bbLZzhK6L1y4YLdvS0A4evSozb537tzp8Dhbi4qKgpeXF44cOYLDhw93qg9b42lPWVkZAKBfv35KWXx8PLRaLUwmE06dOtXlcYwdOxYAkJ+f36FXzVj209mwYYPDbRy5h7ZY9nHZsmWLzTHm5eXh9OnT0Ov1dve5udpGjx6NyMhIeHp6IiUlBf7+/u22scx9bm5uh5427uw8tqdfv37KU6C2fvSJiFIeFxenlMfGxgK4uLeO5fvdWn5+vmovICKi6x0zUtcwIzmOGUmNGYmI6NrHnNQ1zEmOY05SY04iousVF3mJuuC5554DAGRnZ6OgoMCqXkTwzTffYM+ePUrZkCFDAADbtm3Dn3/+qZQ3NzfjiSeewP79+22eq0+fPtBqtfjrr79s/ucPAGPGjAEAvP/++zhy5IhS3tTUhIULF+LgwYMdvMKLNBoNnnzySYgI7rvvPnzxxRdWxzQ3N+Ozzz7D119/7VCfBQUFSE5Oxqefform5marepPJhKeeegoAkJ6erpT7+Phg1qxZqK+vx4QJE1BUVGTVtrGxEfn5+SguLm53HOHh4UhNTUV5eTlSUlJsPkFXX1+PDz74ACdPnlTK5syZA71ej/z8fCxduhRNTU2qNqdOnbKaJ8sPjI7+uJk8eTICAgJQWVmJOXPmqAJpSUkJ5s6dCwCYNWsWdDpdh/q+kg4ePIiqqips3brVoeOTkpIQFRWFAwcOIDs72+ZeKadPn8a6detU12yZx19//dVq3rvK8hTos88+q9r3RETw3HPP4ccff4SHhwceeughpS4mJga33XYbzp07h5kzZ6KxsVGpKy8vvyaeLCUi+rcxI13CjMSMxIzEjERE1Bpz0iXMScxJzEnMSUTURUJEKgaDQQCI0Wh06PiVK1eKi4uLAJDg4GC59957Zdq0aXL33XeLt7e3AJCFCxcqxzc1NUlERIQAEHd3d7n33nslLS1NDAaDaDQaWbhwoQCQ2NhYq3NNmjRJAEj//v1l6tSpMn36dJk+fbrqmKSkJAEgPXv2lLvvvlsmTpwo/fr1kxtvvFFmz54tACQzM1PVxmg02iy/3Pz58wWAAJChQ4dKUlKSpKeny5133ikeHh4CQNauXevQvOXl5Sl99erVS+Li4mTq1KkyceJEGTx4sFI3ZswYqa+vV7VtamqSadOmCQBxdnaW8PBwSU1NlSlTpkh0dLS4ubkJANm5c6eqnaXPy9XW1kp8fLwAEK1WK1FRUZKWliaTJ0+WqKgo0Wq1AkCOHj2qard7927R6/UCQHx8fCQ5OVkmT54st99+u2g0Gqv5XL16tXLfU1JSlPtXXFwsIiIlJSUCQAwGg9UYDxw4IDfddJNSP2XKFBk3bpzodDoBIAkJCdLY2Khq0959bet8bbHMY3l5uUPHFxYWCgAJCgqyqquoqJCwsDABIG5ubjJq1ChJT0+XlJQUCQsLkx49eggAMZvNqnaRkZECQEJDQyUjI0OmT5+u+p5lZma2+T22NzctLS1y//33CwBxcXGR+Ph4mTp1qoSGhirfqx07dlj1d/jwYenTp48AEH9/f0lLS5Px48fLDTfcICNGjJCRI0cKACksLHRozoiIrkXMSPYxIzEjiTAjMSMR0X8Zc5J9zEnMSSLMScxJRHS1cJGX6DIdDeYiIkVFRTJjxgwJCQkRnU4nN9xwgwQGBkpCQoKsWrVKKioqVMfX1dXJ4sWLJTQ0VHQ6nXh7e0tycrJ8++23SoixFcyrq6vl4YcfloCAANFoNDaDZkNDgyxdulQCAwNFo9GIt7e3TJ06VX777Te7YcTRYC4i8uWXX0pGRoYYDAZxdXUVvV4vgwYNkuTkZHnrrbekpqbGoTkzm82ye/duWbBggURHR4vBYBCdTic6nU4CAgIkOTlZtmzZIi0tLXb72LFjh6SkpEjfvn1Fo9GIh4eHDBkyRNLT02XTpk1Wgd5eMBcRaW5ulk2bNsm4cePEx8dHNBqNeHp6yrBhwyQ7O1vy8vLk/PnzVu1KS0tl9uzZyr10d3eXQYMGSU5Ojnz11VdW53j++edl6NChSqBuHdbaC8plZWUyc+ZMCQwMFK1WK3q9XkaOHClr166VpqYmq+O7QzAXufiZXbduncTFxYmnp6e4uLiIt7e3hIWFycyZM2X37t1WbUpLS2XatGni5+en/DBufR2dDeYWmzZtUn5wajQa6d+/v2RlZSk/omwpLS2VrKws8fHxEa1WK4GBgbJw4UKpr6+X2NhYBnMi6vaYkdrGjKTGjNQ+ZiRmJCK6fjAntY05SY05qX3MScxJROQYJ5EOvLyeiIiIiIiIiIiIiIiIiIj+r7gnLxERERERERERERERERFRN8JFXiIiIiIiIiIiIiIiIiKiboSLvERERERERERERERERERE3QgXeYmIiIiIiIiIiIiIiIiIuhEu8hIRERERERERERERERERdSNc5CUiIiIiIiIiIiIiIiIi6ka4yEtERERERERERERERERE1I1wkZeIiIiIiIiIiIiIiIiIqBvhIi8RERERERERERERERERUTfCRV4iIiIiIiIiIiIiIiIiom6Ei7xERERERERERERERERERN0IF3mJiIiIiIiIiIiIiIiIiLoRLvISEREREREREREREREREXUj/wMcnUR2xHTsvgAAAABJRU5ErkJggg==",
      "text/plain": [
       "<Figure size 1913.5x500 with 3 Axes>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "g = sns.FacetGrid(df_melted, col=\"Feature\", sharey=False, height=5, aspect=1.2, ylim=(0,1))#col_order=['Train_Accuracy', 'Test_Accuracy']\n",
    "g.map_dataframe(sns.barplot, x=\"Version\", y=\"Score\", hue='Metric', palette='muted')\n",
    "g.set_axis_labels(\"Feature Selection Method\", \"Score\", size=16)\n",
    "\n",
    "\n",
    "axes = g.axes.flatten()\n",
    "axes[0].set_title(\"Activity\", size=16)\n",
    "axes[1].set_title(\"Hemolysis\", size=16)\n",
    "axes[2].set_title(\"Selectivity\", size=16)\n",
    "\n",
    "tick_labels = ['Correlation', 'PCA']\n",
    "for ax in axes: \n",
    "    ax.set_xticks(range(len(tick_labels)))  # Set x-tick positions\n",
    "    ax.set_xticklabels(tick_labels, size=12) \n",
    "\n",
    "\n",
    "g.add_legend()\n",
    "#plt.savefig('results/model_v01.2-2_performance.png', dpi=1200)\n",
    "plt.show()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {},
   "outputs": [],
   "source": []
  }
 ],
 "metadata": {
  "kernelspec": {
   "display_name": "ML",
   "language": "python",
   "name": "python3"
  },
  "language_info": {
   "codemirror_mode": {
    "name": "ipython",
    "version": 3
   },
   "file_extension": ".py",
   "mimetype": "text/x-python",
   "name": "python",
   "nbconvert_exporter": "python",
   "pygments_lexer": "ipython3",
   "version": "3.8.10"
  }
 },
 "nbformat": 4,
 "nbformat_minor": 2
}