MergeCilio.ipynb

{
 "cells": [
  {
   "cell_type": "code",
   "execution_count": 3,
   "id": "9bba8b64",
   "metadata": {
    "collapsed": true
   },
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "'getOption(\"repos\")' replaces Bioconductor standard repositories, see\n",
      "'?repositories' for details\n",
      "\n",
      "replacement repositories:\n",
      "    CRAN: https://cran.r-project.org\n",
      "\n",
      "\n",
      "Bioconductor version 3.14 (BiocManager 1.30.18), R 4.1.3 (2022-03-10)\n",
      "\n",
      "Installing package(s) 'tidyverse'\n",
      "\n",
      "also installing the dependencies ‘rematch’, ‘gargle’, ‘cellranger’, ‘ids’, ‘vroom’, ‘tzdb’, ‘selectr’, ‘broom’, ‘dtplyr’, ‘forcats’, ‘googledrive’, ‘googlesheets4’, ‘haven’, ‘modelr’, ‘readr’, ‘readxl’, ‘reprex’, ‘rvest’\n",
      "\n",
      "\n",
      "Updating HTML index of packages in '.Library'\n",
      "\n",
      "Making 'packages.html' ...\n",
      " done\n",
      "\n",
      "Old packages: 'FNN', 'gtools', 'randomForest'\n",
      "\n"
     ]
    }
   ],
   "source": [
    "# BiocManager::install(\"tidyverse\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 1,
   "id": "2b104f93",
   "metadata": {},
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "Loading required package: snowfall\n",
      "\n",
      "Loading required package: snow\n",
      "\n",
      "Warning message:\n",
      "“replacing previous import ‘gplots::lowess’ by ‘stats::lowess’ when loading ‘TED’”\n"
     ]
    }
   ],
   "source": [
    "# library(SingleCellExperiment)\n",
    "# library(devtools)\n",
    "library(TED)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 21,
   "id": "ab3372f3",
   "metadata": {},
   "outputs": [],
   "source": [
    "#load in BP demo data in vignette\n",
    "load(\"/home/cke/BPexample_gbm.rdata\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 33,
   "id": "6f0d0f51",
   "metadata": {
    "scrolled": true
   },
   "outputs": [],
   "source": [
    "length(t(ref.dat))"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 19,
   "id": "c048cdf7",
   "metadata": {},
   "outputs": [],
   "source": [
    "?run.Ted\n",
    "# ?cleanup.genes"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "id": "5df8c9aa",
   "metadata": {},
   "outputs": [],
   "source": [
    "df_Puram<-read.table(\"/home/cke/Puram/HNSCC2PuramGSE103322_HNSCC_exp.tsv\",sep='\\t',header=TRUE)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 4,
   "id": "ca9ab223",
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
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       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A data.frame: 21813 × 5903\n",
       "\\begin{tabular}{lllllllllllllllllllll}\n",
       " X & HN28\\_P15\\_D06\\_S330\\_comb & HN28\\_P6\\_G05\\_S173\\_comb & HN26\\_P14\\_D11\\_S239\\_comb & HN26\\_P14\\_H05\\_S281\\_comb & HN26\\_P25\\_H09\\_S189\\_comb & HN26\\_P14\\_H06\\_S282\\_comb & HN25\\_P25\\_C04\\_S316\\_comb & HN26\\_P25\\_A11\\_S107\\_comb & HN26\\_P25\\_C09\\_S129\\_comb & ⋯ & HNSCC20\\_P3\\_B10\\_S22\\_comb & HNSCC20\\_P13\\_B11\\_S215\\_comb & HNSCC20\\_P3\\_C08\\_S32\\_comb & HNSCC17\\_P4\\_H03\\_S183\\_comb & HNSCC20\\_P3\\_F09\\_S69\\_comb & HNSCC17\\_P4\\_G12\\_S180\\_comb & HNSCC20\\_P13\\_C05\\_S221\\_comb & HNSCC17\\_P4\\_C12\\_S132\\_comb & HNSCC20\\_P3\\_H08\\_S92\\_comb & HNSCC20\\_P3\\_G06\\_S78\\_comb\\\\\n",
       " <chr> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & ⋯ & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl>\\\\\n",
       "\\hline\n",
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       "\t ENSG00000268895 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & ⋯ & 0.00000 & 1.064200 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.00000\\\\\n",
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       "\t ENSG00000109576 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.078610 & 0.000000 & 0.00000 & 2.47900 & 0.000000 & ⋯ & 0.00000 & 0.000000 & 0.00000 & 0.00000 & 0.286880 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.00000\\\\\n",
       "\t ENSG00000158122 & 0.000000 & 0.00000 & 0.000000 & 5.096100 & 0.000000 & 0.956060 & 0.00000 & 0.00000 & 0.000000 & ⋯ & 0.00000 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.00000 & 2.310000 & 0.00000 & 0.00000\\\\\n",
       "\t ENSG00000103591 & 0.000000 & 0.91533 & 2.602400 & 0.000000 & 0.000000 & 2.718300 & 0.00000 & 3.27560 & 0.000000 & ⋯ & 4.33260 & 2.992600 & 3.47310 & 0.00000 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & 0.59455 & 0.38736\\\\\n",
       "\t ENSG00000115977 & 0.038436 & 0.13488 & 0.684370 & 0.057970 & 0.039840 & 0.034216 & 0.25942 & 0.00000 & 0.027154 & ⋯ & 0.08134 & 0.063503 & 0.39177 & 0.02148 & 1.144700 & 0.14405 & 2.17540 & 0.014355 & 0.10702 & 0.10030\\\\\n",
       "\t ENSG00000087884 & 0.000000 & 0.00000 & 0.000000 & 2.152500 & 0.000000 & 0.332280 & 0.00000 & 0.00000 & 0.000000 & ⋯ & 0.00000 & 0.000000 & 3.80050 & 5.09490 & 0.000000 & 5.41960 & 0.00000 & 4.338900 & 0.00000 & 0.00000\\\\\n",
       "\t ENSG00000127837 & 0.000000 & 0.00000 & 4.472600 & 0.000000 & 3.531400 & 4.901700 & 0.00000 & 0.00000 & 4.569300 & ⋯ & 4.16740 & 3.405400 & 5.66740 & 4.69760 & 3.667100 & 0.00000 & 0.00000 & 4.172200 & 6.25820 & 5.66890\\\\\n",
       "\t ENSG00000129673 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & ⋯ & 0.00000 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.00000\\\\\n",
       "\t ENSG00000131043 & 0.000000 & 0.00000 & 4.706200 & 6.485600 & 0.652600 & 0.969380 & 0.00000 & 0.00000 & 0.000000 & ⋯ & 1.74670 & 0.000000 & 0.00000 & 3.19870 & 2.109400 & 1.95830 & 0.00000 & 0.000000 & 2.82780 & 0.00000\\\\\n",
       "\t ENSG00000205002 & 0.211640 & 0.00000 & 0.092207 & 0.163500 & 0.107020 & 0.000000 & 0.00000 & 0.00000 & 0.113700 & ⋯ & 0.28451 & 0.000000 & 0.00000 & 0.00000 & 0.178870 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.00000\\\\\n",
       "\t ENSG00000090861 & 0.000000 & 0.00000 & 3.425700 & 0.000000 & 0.678970 & 5.286000 & 0.00000 & 0.00000 & 0.000000 & ⋯ & 5.32560 & 4.501500 & 3.39790 & 0.00000 & 7.205100 & 4.60440 & 2.36740 & 0.000000 & 5.82340 & 4.35730\\\\\n",
       "\t ENSG00000124608 & 0.000000 & 0.18777 & 0.048236 & 0.059355 & 0.071763 & 1.926000 & 0.43829 & 0.00000 & 0.000000 & ⋯ & 0.11103 & 0.000000 & 0.11237 & 0.00000 & 0.066261 & 0.15186 & 0.25822 & 3.598200 & 3.55880 & 3.56660\\\\\n",
       "\t ENSG00000266967 & 0.000000 & 0.00000 & 3.822900 & 0.000000 & 4.034200 & 3.296500 & 0.00000 & 0.00000 & 0.000000 & ⋯ & 2.93790 & 2.835300 & 3.82950 & 4.95510 & 4.196400 & 0.00000 & 0.00000 & 0.000000 & 2.30920 & 2.26090\\\\\n",
       "\t ENSG00000157426 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 2.871300 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & ⋯ & 2.28040 & 0.783250 & 0.00000 & 0.00000 & 0.000000 & 2.09390 & 2.29100 & 0.000000 & 1.29870 & 0.00000\\\\\n",
       "\t ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋱ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n",
       "\t ENSG00000197062 & 2.362300 & 0.00000 & 2.895300 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & ⋯ & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 2.641100 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000140265 & 0.109690 & 0.00000 & 0.142740 & 0.240010 & 0.039840 & 0.057970 & 0.56852 & 3.308900 & 0.133560 & ⋯ & 0.150560 & 1.31320 & 0.092207 & 0.000000 & 0.459430 & 0.27023 & 0.61070 & 0.028569 & 2.85160 & 0.125650\\\\\n",
       "\t ENSG00000186814 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.079975 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & ⋯ & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000235109 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & ⋯ & 3.177900 & 2.18210 & 2.527100 & 0.000000 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & 3.32380 & 0.000000\\\\\n",
       "\t ENSG00000140987 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 2.807800 & 0.00000 & 0.000000 & 0.000000 & ⋯ & 2.427300 & 1.99750 & 0.000000 & 0.000000 & 1.760400 & 0.00000 & 4.98220 & 0.000000 & 3.75320 & 0.000000\\\\\n",
       "\t ENSG00000180532 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & ⋯ & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000131848 & 0.000000 & 0.00000 & 3.628000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & ⋯ & 3.225100 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 4.86800 & 0.000000 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000197213 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & ⋯ & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.35952 & 0.000000 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000137185 & 0.000000 & 0.00000 & 3.830800 & 6.634300 & 0.000000 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & ⋯ & 0.000000 & 0.85439 & 3.412000 & 0.000000 & 3.296500 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000168612 & 0.000000 & 0.58688 & 0.051024 & 0.105680 & 0.175050 & 0.044044 & 1.14270 & 0.104340 & 0.201630 & ⋯ & 2.539000 & 0.20914 & 0.186500 & 0.000000 & 0.000000 & 0.42653 & 0.21164 & 0.000000 & 3.66050 & 0.341420\\\\\n",
       "\t ENSG00000163012 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & ⋯ & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000132801 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & ⋯ & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000132003 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.059355 & 0.000000 & ⋯ & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000162415 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.169930 & 0.018634 & 0.00000 & 1.460000 & 0.000000 & ⋯ & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000130449 & 0.069015 & 0.00000 & 0.000000 & 0.000000 & 0.207890 & 0.000000 & 0.00000 & 0.753600 & 0.000000 & ⋯ & 0.574340 & 0.59932 & 0.000000 & 0.000000 & 0.310340 & 0.00000 & 2.11440 & 0.000000 & 1.77060 & 0.000000\\\\\n",
       "\t ENSG00000214941 & 0.000000 & 0.00000 & 2.963100 & 0.000000 & 2.879500 & 3.154600 & 0.00000 & 0.000000 & 0.000000 & ⋯ & 0.227740 & 2.57750 & 0.278580 & 0.000000 & 1.983300 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000214655 & 2.788100 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 1.394000 & 0.237560 & ⋯ & 0.070389 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 3.09070 & 0.821300 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000272589 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & ⋯ & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000153975 & 0.000000 & 0.00000 & 4.172500 & 0.000000 & 0.000000 & 0.000000 & 4.39710 & 0.000000 & 4.787500 & ⋯ & 1.000700 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 2.25850 & 0.48954 & 0.000000 & 3.78200 & 0.000000\\\\\n",
       "\t ENSG00000086827 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 2.017200 & 0.00000 & 4.216400 & 0.000000 & ⋯ & 2.346200 & 2.06630 & 0.000000 & 4.277300 & 0.000000 & 0.00000 & 0.00000 & 3.737300 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000174442 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.871840 & 0.00000 & 4.634800 & 0.000000 & ⋯ & 1.551400 & 2.88520 & 2.122000 & 0.000000 & 0.000000 & 0.00000 & 0.00000 & 0.101650 & 3.59690 & 0.000000\\\\\n",
       "\t ENSG00000122952 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & ⋯ & 3.049100 & 4.54920 & 0.000000 & 4.535600 & 0.000000 & 0.00000 & 0.00000 & 3.473700 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000198205 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & ⋯ & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000198455 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & 2.138500 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & ⋯ & 0.709290 & 0.00000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000070476 & 0.121680 & 0.19535 & 0.021480 & 0.089498 & 0.228970 & 1.201600 & 0.36289 & 0.097611 & 0.062122 & ⋯ & 1.441500 & 0.00000 & 0.041243 & 0.012926 & 0.606920 & 4.18860 & 0.24732 & 0.000000 & 0.15704 & 0.034216\\\\\n",
       "\t ENSG00000203995 & 0.163500 & 0.27977 & 0.000000 & 0.186500 & 0.133560 & 0.063503 & 1.08810 & 0.067639 & 0.032806 & ⋯ & 0.000000 & 0.20163 & 0.000000 & 0.000000 & 0.000000 & 0.39835 & 0.74674 & 0.000000 & 0.23634 & 0.000000\\\\\n",
       "\t ENSG00000162378 & 0.090853 & 3.93480 & 0.073135 & 0.214120 & 2.905900 & 0.051024 & 0.85599 & 0.000000 & 0.092207 & ⋯ & 0.737250 & 0.00000 & 0.000000 & 0.037031 & 0.039840 & 0.25459 & 0.31846 & 2.106300 & 0.29160 & 0.111030\\\\\n",
       "\t ENSG00000159840 & 4.274800 & 0.00000 & 0.000000 & 0.124330 & 3.003400 & 0.605020 & 0.00000 & 5.292800 & 0.000000 & ⋯ & 3.382800 & 1.00070 & 2.524300 & 0.000000 & 0.677170 & 0.75275 & 0.00000 & 4.055700 & 3.73420 & 0.000000\\\\\n",
       "\t ENSG00000074755 & 0.000000 & 3.77160 & 1.304500 & 0.093560 & 0.000000 & 0.000000 & 0.85679 & 0.000000 & 0.017209 & ⋯ & 0.107020 & 0.57531 & 0.172490 & 0.000000 & 1.017900 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.000000\\\\\n",
       "\t ENSG00000036549 & 0.000000 & 0.00000 & 2.112000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.000000 & 0.000000 & ⋯ & 2.233300 & 1.68080 & 0.000000 & 0.000000 & 0.071763 & 0.00000 & 0.00000 & 0.000000 & 0.00000 & 0.000000\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A data.frame: 21813 × 5903\n",
       "\n",
       "| X &lt;chr&gt; | HN28_P15_D06_S330_comb &lt;dbl&gt; | HN28_P6_G05_S173_comb &lt;dbl&gt; | HN26_P14_D11_S239_comb &lt;dbl&gt; | HN26_P14_H05_S281_comb &lt;dbl&gt; | HN26_P25_H09_S189_comb &lt;dbl&gt; | HN26_P14_H06_S282_comb &lt;dbl&gt; | HN25_P25_C04_S316_comb &lt;dbl&gt; | HN26_P25_A11_S107_comb &lt;dbl&gt; | HN26_P25_C09_S129_comb &lt;dbl&gt; | ⋯ ⋯ | HNSCC20_P3_B10_S22_comb &lt;dbl&gt; | HNSCC20_P13_B11_S215_comb &lt;dbl&gt; | HNSCC20_P3_C08_S32_comb &lt;dbl&gt; | HNSCC17_P4_H03_S183_comb &lt;dbl&gt; | HNSCC20_P3_F09_S69_comb &lt;dbl&gt; | HNSCC17_P4_G12_S180_comb &lt;dbl&gt; | HNSCC20_P13_C05_S221_comb &lt;dbl&gt; | HNSCC17_P4_C12_S132_comb &lt;dbl&gt; | HNSCC20_P3_H08_S92_comb &lt;dbl&gt; | HNSCC20_P3_G06_S78_comb &lt;dbl&gt; |\n",
       "|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|\n",
       "| ENSG00000121410 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.066261 | 0.00000 | 0.54102 | 0.000000 | ⋯ | 0.63320 | 1.225900 | 1.37740 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 2.99960 | 0.00000 |\n",
       "| ENSG00000268895 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 0.00000 | 1.064200 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 |\n",
       "| ENSG00000148584 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 |\n",
       "| ENSG00000175899 | 9.683000 | 7.58300 | 0.029983 | 6.054700 | 0.000000 | 0.000000 | 0.19661 | 7.70600 | 0.000000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 |\n",
       "| ENSG00000245105 | 0.176320 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 |\n",
       "| ENSG00000166535 | 0.000000 | 0.00000 | 4.798800 | 0.000000 | 0.000000 | 2.283000 | 0.00000 | 0.00000 | 1.125000 | ⋯ | 0.31150 | 5.735100 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.042644 | 0.00000 | 3.40600 |\n",
       "| ENSG00000256069 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 |\n",
       "| ENSG00000128274 | 2.248800 | 0.00000 | 0.000000 | 0.264240 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 5.18090 | 3.655200 | 5.05750 | 0.00000 | 2.688900 | 0.00000 | 5.08770 | 1.811100 | 3.83700 | 4.34800 |\n",
       "| ENSG00000118017 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 |\n",
       "| ENSG00000265544 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 |\n",
       "| ENSG00000094914 | 4.542300 | 4.69200 | 0.000000 | 0.000000 | 4.778500 | 3.122500 | 5.37640 | 4.13040 | 0.000000 | ⋯ | 0.00000 | 2.040500 | 3.31510 | 4.38080 | 0.000000 | 0.00000 | 0.00000 | 3.652800 | 4.07110 | 0.00000 |\n",
       "| ENSG00000081760 | 3.564100 | 0.00000 | 0.000000 | 0.000000 | 0.960510 | 0.381840 | 5.82300 | 0.00000 | 0.000000 | ⋯ | 0.00000 | 3.939700 | 3.80000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 2.802200 | 0.00000 | 0.13093 |\n",
       "| ENSG00000250420 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 |\n",
       "| ENSG00000114771 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 2.824400 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 |\n",
       "| ENSG00000197953 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 |\n",
       "| ENSG00000188984 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 |\n",
       "| ENSG00000204518 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 |\n",
       "| ENSG00000109576 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.078610 | 0.000000 | 0.00000 | 2.47900 | 0.000000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.286880 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 |\n",
       "| ENSG00000158122 | 0.000000 | 0.00000 | 0.000000 | 5.096100 | 0.000000 | 0.956060 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 2.310000 | 0.00000 | 0.00000 |\n",
       "| ENSG00000103591 | 0.000000 | 0.91533 | 2.602400 | 0.000000 | 0.000000 | 2.718300 | 0.00000 | 3.27560 | 0.000000 | ⋯ | 4.33260 | 2.992600 | 3.47310 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.59455 | 0.38736 |\n",
       "| ENSG00000115977 | 0.038436 | 0.13488 | 0.684370 | 0.057970 | 0.039840 | 0.034216 | 0.25942 | 0.00000 | 0.027154 | ⋯ | 0.08134 | 0.063503 | 0.39177 | 0.02148 | 1.144700 | 0.14405 | 2.17540 | 0.014355 | 0.10702 | 0.10030 |\n",
       "| ENSG00000087884 | 0.000000 | 0.00000 | 0.000000 | 2.152500 | 0.000000 | 0.332280 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 0.00000 | 0.000000 | 3.80050 | 5.09490 | 0.000000 | 5.41960 | 0.00000 | 4.338900 | 0.00000 | 0.00000 |\n",
       "| ENSG00000127837 | 0.000000 | 0.00000 | 4.472600 | 0.000000 | 3.531400 | 4.901700 | 0.00000 | 0.00000 | 4.569300 | ⋯ | 4.16740 | 3.405400 | 5.66740 | 4.69760 | 3.667100 | 0.00000 | 0.00000 | 4.172200 | 6.25820 | 5.66890 |\n",
       "| ENSG00000129673 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 |\n",
       "| ENSG00000131043 | 0.000000 | 0.00000 | 4.706200 | 6.485600 | 0.652600 | 0.969380 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 1.74670 | 0.000000 | 0.00000 | 3.19870 | 2.109400 | 1.95830 | 0.00000 | 0.000000 | 2.82780 | 0.00000 |\n",
       "| ENSG00000205002 | 0.211640 | 0.00000 | 0.092207 | 0.163500 | 0.107020 | 0.000000 | 0.00000 | 0.00000 | 0.113700 | ⋯ | 0.28451 | 0.000000 | 0.00000 | 0.00000 | 0.178870 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.00000 |\n",
       "| ENSG00000090861 | 0.000000 | 0.00000 | 3.425700 | 0.000000 | 0.678970 | 5.286000 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 5.32560 | 4.501500 | 3.39790 | 0.00000 | 7.205100 | 4.60440 | 2.36740 | 0.000000 | 5.82340 | 4.35730 |\n",
       "| ENSG00000124608 | 0.000000 | 0.18777 | 0.048236 | 0.059355 | 0.071763 | 1.926000 | 0.43829 | 0.00000 | 0.000000 | ⋯ | 0.11103 | 0.000000 | 0.11237 | 0.00000 | 0.066261 | 0.15186 | 0.25822 | 3.598200 | 3.55880 | 3.56660 |\n",
       "| ENSG00000266967 | 0.000000 | 0.00000 | 3.822900 | 0.000000 | 4.034200 | 3.296500 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 2.93790 | 2.835300 | 3.82950 | 4.95510 | 4.196400 | 0.00000 | 0.00000 | 0.000000 | 2.30920 | 2.26090 |\n",
       "| ENSG00000157426 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 2.871300 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | ⋯ | 2.28040 | 0.783250 | 0.00000 | 0.00000 | 0.000000 | 2.09390 | 2.29100 | 0.000000 | 1.29870 | 0.00000 |\n",
       "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋱ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ |\n",
       "| ENSG00000197062 | 2.362300 | 0.00000 | 2.895300 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | ⋯ | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 2.641100 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 |\n",
       "| ENSG00000140265 | 0.109690 | 0.00000 | 0.142740 | 0.240010 | 0.039840 | 0.057970 | 0.56852 | 3.308900 | 0.133560 | ⋯ | 0.150560 | 1.31320 | 0.092207 | 0.000000 | 0.459430 | 0.27023 | 0.61070 | 0.028569 | 2.85160 | 0.125650 |\n",
       "| ENSG00000186814 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.079975 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | ⋯ | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 |\n",
       "| ENSG00000235109 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | ⋯ | 3.177900 | 2.18210 | 2.527100 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 3.32380 | 0.000000 |\n",
       "| ENSG00000140987 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 2.807800 | 0.00000 | 0.000000 | 0.000000 | ⋯ | 2.427300 | 1.99750 | 0.000000 | 0.000000 | 1.760400 | 0.00000 | 4.98220 | 0.000000 | 3.75320 | 0.000000 |\n",
       "| ENSG00000180532 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | ⋯ | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 |\n",
       "| ENSG00000131848 | 0.000000 | 0.00000 | 3.628000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | ⋯ | 3.225100 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 4.86800 | 0.000000 | 0.00000 | 0.000000 |\n",
       "| ENSG00000197213 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | ⋯ | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.35952 | 0.000000 | 0.00000 | 0.000000 |\n",
       "| ENSG00000137185 | 0.000000 | 0.00000 | 3.830800 | 6.634300 | 0.000000 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | ⋯ | 0.000000 | 0.85439 | 3.412000 | 0.000000 | 3.296500 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 |\n",
       "| ENSG00000168612 | 0.000000 | 0.58688 | 0.051024 | 0.105680 | 0.175050 | 0.044044 | 1.14270 | 0.104340 | 0.201630 | ⋯ | 2.539000 | 0.20914 | 0.186500 | 0.000000 | 0.000000 | 0.42653 | 0.21164 | 0.000000 | 3.66050 | 0.341420 |\n",
       "| ENSG00000163012 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | ⋯ | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 |\n",
       "| ENSG00000132801 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | ⋯ | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 |\n",
       "| ENSG00000132003 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.059355 | 0.000000 | ⋯ | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 |\n",
       "| ENSG00000162415 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.169930 | 0.018634 | 0.00000 | 1.460000 | 0.000000 | ⋯ | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 |\n",
       "| ENSG00000130449 | 0.069015 | 0.00000 | 0.000000 | 0.000000 | 0.207890 | 0.000000 | 0.00000 | 0.753600 | 0.000000 | ⋯ | 0.574340 | 0.59932 | 0.000000 | 0.000000 | 0.310340 | 0.00000 | 2.11440 | 0.000000 | 1.77060 | 0.000000 |\n",
       "| ENSG00000214941 | 0.000000 | 0.00000 | 2.963100 | 0.000000 | 2.879500 | 3.154600 | 0.00000 | 0.000000 | 0.000000 | ⋯ | 0.227740 | 2.57750 | 0.278580 | 0.000000 | 1.983300 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 |\n",
       "| ENSG00000214655 | 2.788100 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 1.394000 | 0.237560 | ⋯ | 0.070389 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 3.09070 | 0.821300 | 0.00000 | 0.000000 |\n",
       "| ENSG00000272589 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | ⋯ | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 |\n",
       "| ENSG00000153975 | 0.000000 | 0.00000 | 4.172500 | 0.000000 | 0.000000 | 0.000000 | 4.39710 | 0.000000 | 4.787500 | ⋯ | 1.000700 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 2.25850 | 0.48954 | 0.000000 | 3.78200 | 0.000000 |\n",
       "| ENSG00000086827 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 2.017200 | 0.00000 | 4.216400 | 0.000000 | ⋯ | 2.346200 | 2.06630 | 0.000000 | 4.277300 | 0.000000 | 0.00000 | 0.00000 | 3.737300 | 0.00000 | 0.000000 |\n",
       "| ENSG00000174442 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.871840 | 0.00000 | 4.634800 | 0.000000 | ⋯ | 1.551400 | 2.88520 | 2.122000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.101650 | 3.59690 | 0.000000 |\n",
       "| ENSG00000122952 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | ⋯ | 3.049100 | 4.54920 | 0.000000 | 4.535600 | 0.000000 | 0.00000 | 0.00000 | 3.473700 | 0.00000 | 0.000000 |\n",
       "| ENSG00000198205 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | ⋯ | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 |\n",
       "| ENSG00000198455 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | 2.138500 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | ⋯ | 0.709290 | 0.00000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 |\n",
       "| ENSG00000070476 | 0.121680 | 0.19535 | 0.021480 | 0.089498 | 0.228970 | 1.201600 | 0.36289 | 0.097611 | 0.062122 | ⋯ | 1.441500 | 0.00000 | 0.041243 | 0.012926 | 0.606920 | 4.18860 | 0.24732 | 0.000000 | 0.15704 | 0.034216 |\n",
       "| ENSG00000203995 | 0.163500 | 0.27977 | 0.000000 | 0.186500 | 0.133560 | 0.063503 | 1.08810 | 0.067639 | 0.032806 | ⋯ | 0.000000 | 0.20163 | 0.000000 | 0.000000 | 0.000000 | 0.39835 | 0.74674 | 0.000000 | 0.23634 | 0.000000 |\n",
       "| ENSG00000162378 | 0.090853 | 3.93480 | 0.073135 | 0.214120 | 2.905900 | 0.051024 | 0.85599 | 0.000000 | 0.092207 | ⋯ | 0.737250 | 0.00000 | 0.000000 | 0.037031 | 0.039840 | 0.25459 | 0.31846 | 2.106300 | 0.29160 | 0.111030 |\n",
       "| ENSG00000159840 | 4.274800 | 0.00000 | 0.000000 | 0.124330 | 3.003400 | 0.605020 | 0.00000 | 5.292800 | 0.000000 | ⋯ | 3.382800 | 1.00070 | 2.524300 | 0.000000 | 0.677170 | 0.75275 | 0.00000 | 4.055700 | 3.73420 | 0.000000 |\n",
       "| ENSG00000074755 | 0.000000 | 3.77160 | 1.304500 | 0.093560 | 0.000000 | 0.000000 | 0.85679 | 0.000000 | 0.017209 | ⋯ | 0.107020 | 0.57531 | 0.172490 | 0.000000 | 1.017900 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 |\n",
       "| ENSG00000036549 | 0.000000 | 0.00000 | 2.112000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.000000 | 0.000000 | ⋯ | 2.233300 | 1.68080 | 0.000000 | 0.000000 | 0.071763 | 0.00000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 |\n",
       "\n"
      ],
      "text/plain": [
       "      X               HN28_P15_D06_S330_comb HN28_P6_G05_S173_comb\n",
       "1     ENSG00000121410 0.000000               0.00000              \n",
       "2     ENSG00000268895 0.000000               0.00000              \n",
       "3     ENSG00000148584 0.000000               0.00000              \n",
       "4     ENSG00000175899 9.683000               7.58300              \n",
       "5     ENSG00000245105 0.176320               0.00000              \n",
       "6     ENSG00000166535 0.000000               0.00000              \n",
       "7     ENSG00000256069 0.000000               0.00000              \n",
       "8     ENSG00000128274 2.248800               0.00000              \n",
       "9     ENSG00000118017 0.000000               0.00000              \n",
       "10    ENSG00000265544 0.000000               0.00000              \n",
       "11    ENSG00000094914 4.542300               4.69200              \n",
       "12    ENSG00000081760 3.564100               0.00000              \n",
       "13    ENSG00000250420 0.000000               0.00000              \n",
       "14    ENSG00000114771 0.000000               0.00000              \n",
       "15    ENSG00000197953 0.000000               0.00000              \n",
       "16    ENSG00000188984 0.000000               0.00000              \n",
       "17    ENSG00000204518 0.000000               0.00000              \n",
       "18    ENSG00000109576 0.000000               0.00000              \n",
       "19    ENSG00000158122 0.000000               0.00000              \n",
       "20    ENSG00000103591 0.000000               0.91533              \n",
       "21    ENSG00000115977 0.038436               0.13488              \n",
       "22    ENSG00000087884 0.000000               0.00000              \n",
       "23    ENSG00000127837 0.000000               0.00000              \n",
       "24    ENSG00000129673 0.000000               0.00000              \n",
       "25    ENSG00000131043 0.000000               0.00000              \n",
       "26    ENSG00000205002 0.211640               0.00000              \n",
       "27    ENSG00000090861 0.000000               0.00000              \n",
       "28    ENSG00000124608 0.000000               0.18777              \n",
       "29    ENSG00000266967 0.000000               0.00000              \n",
       "30    ENSG00000157426 0.000000               0.00000              \n",
       "⋮     ⋮               ⋮                      ⋮                    \n",
       "21784 ENSG00000197062 2.362300               0.00000              \n",
       "21785 ENSG00000140265 0.109690               0.00000              \n",
       "21786 ENSG00000186814 0.000000               0.00000              \n",
       "21787 ENSG00000235109 0.000000               0.00000              \n",
       "21788 ENSG00000140987 0.000000               0.00000              \n",
       "21789 ENSG00000180532 0.000000               0.00000              \n",
       "21790 ENSG00000131848 0.000000               0.00000              \n",
       "21791 ENSG00000197213 0.000000               0.00000              \n",
       "21792 ENSG00000137185 0.000000               0.00000              \n",
       "21793 ENSG00000168612 0.000000               0.58688              \n",
       "21794 ENSG00000163012 0.000000               0.00000              \n",
       "21795 ENSG00000132801 0.000000               0.00000              \n",
       "21796 ENSG00000132003 0.000000               0.00000              \n",
       "21797 ENSG00000162415 0.000000               0.00000              \n",
       "21798 ENSG00000130449 0.069015               0.00000              \n",
       "21799 ENSG00000214941 0.000000               0.00000              \n",
       "21800 ENSG00000214655 2.788100               0.00000              \n",
       "21801 ENSG00000272589 0.000000               0.00000              \n",
       "21802 ENSG00000153975 0.000000               0.00000              \n",
       "21803 ENSG00000086827 0.000000               0.00000              \n",
       "21804 ENSG00000174442 0.000000               0.00000              \n",
       "21805 ENSG00000122952 0.000000               0.00000              \n",
       "21806 ENSG00000198205 0.000000               0.00000              \n",
       "21807 ENSG00000198455 0.000000               0.00000              \n",
       "21808 ENSG00000070476 0.121680               0.19535              \n",
       "21809 ENSG00000203995 0.163500               0.27977              \n",
       "21810 ENSG00000162378 0.090853               3.93480              \n",
       "21811 ENSG00000159840 4.274800               0.00000              \n",
       "21812 ENSG00000074755 0.000000               3.77160              \n",
       "21813 ENSG00000036549 0.000000               0.00000              \n",
       "      HN26_P14_D11_S239_comb HN26_P14_H05_S281_comb HN26_P25_H09_S189_comb\n",
       "1     0.000000               0.000000               0.000000              \n",
       "2     0.000000               0.000000               0.000000              \n",
       "3     0.000000               0.000000               0.000000              \n",
       "4     0.029983               6.054700               0.000000              \n",
       "5     0.000000               0.000000               0.000000              \n",
       "6     4.798800               0.000000               0.000000              \n",
       "7     0.000000               0.000000               0.000000              \n",
       "8     0.000000               0.264240               0.000000              \n",
       "9     0.000000               0.000000               0.000000              \n",
       "10    0.000000               0.000000               0.000000              \n",
       "11    0.000000               0.000000               4.778500              \n",
       "12    0.000000               0.000000               0.960510              \n",
       "13    0.000000               0.000000               0.000000              \n",
       "14    0.000000               0.000000               0.000000              \n",
       "15    0.000000               0.000000               0.000000              \n",
       "16    0.000000               0.000000               0.000000              \n",
       "17    0.000000               0.000000               0.000000              \n",
       "18    0.000000               0.000000               0.078610              \n",
       "19    0.000000               5.096100               0.000000              \n",
       "20    2.602400               0.000000               0.000000              \n",
       "21    0.684370               0.057970               0.039840              \n",
       "22    0.000000               2.152500               0.000000              \n",
       "23    4.472600               0.000000               3.531400              \n",
       "24    0.000000               0.000000               0.000000              \n",
       "25    4.706200               6.485600               0.652600              \n",
       "26    0.092207               0.163500               0.107020              \n",
       "27    3.425700               0.000000               0.678970              \n",
       "28    0.048236               0.059355               0.071763              \n",
       "29    3.822900               0.000000               4.034200              \n",
       "30    0.000000               0.000000               2.871300              \n",
       "⋮     ⋮                      ⋮                      ⋮                     \n",
       "21784 2.895300               0.000000               0.000000              \n",
       "21785 0.142740               0.240010               0.039840              \n",
       "21786 0.000000               0.000000               0.079975              \n",
       "21787 0.000000               0.000000               0.000000              \n",
       "21788 0.000000               0.000000               0.000000              \n",
       "21789 0.000000               0.000000               0.000000              \n",
       "21790 3.628000               0.000000               0.000000              \n",
       "21791 0.000000               0.000000               0.000000              \n",
       "21792 3.830800               6.634300               0.000000              \n",
       "21793 0.051024               0.105680               0.175050              \n",
       "21794 0.000000               0.000000               0.000000              \n",
       "21795 0.000000               0.000000               0.000000              \n",
       "21796 0.000000               0.000000               0.000000              \n",
       "21797 0.000000               0.000000               0.169930              \n",
       "21798 0.000000               0.000000               0.207890              \n",
       "21799 2.963100               0.000000               2.879500              \n",
       "21800 0.000000               0.000000               0.000000              \n",
       "21801 0.000000               0.000000               0.000000              \n",
       "21802 4.172500               0.000000               0.000000              \n",
       "21803 0.000000               0.000000               0.000000              \n",
       "21804 0.000000               0.000000               0.000000              \n",
       "21805 0.000000               0.000000               0.000000              \n",
       "21806 0.000000               0.000000               0.000000              \n",
       "21807 0.000000               0.000000               2.138500              \n",
       "21808 0.021480               0.089498               0.228970              \n",
       "21809 0.000000               0.186500               0.133560              \n",
       "21810 0.073135               0.214120               2.905900              \n",
       "21811 0.000000               0.124330               3.003400              \n",
       "21812 1.304500               0.093560               0.000000              \n",
       "21813 2.112000               0.000000               0.000000              \n",
       "      HN26_P14_H06_S282_comb HN25_P25_C04_S316_comb HN26_P25_A11_S107_comb\n",
       "1     0.066261               0.00000                0.54102               \n",
       "2     0.000000               0.00000                0.00000               \n",
       "3     0.000000               0.00000                0.00000               \n",
       "4     0.000000               0.19661                7.70600               \n",
       "5     0.000000               0.00000                0.00000               \n",
       "6     2.283000               0.00000                0.00000               \n",
       "7     0.000000               0.00000                0.00000               \n",
       "8     0.000000               0.00000                0.00000               \n",
       "9     0.000000               0.00000                0.00000               \n",
       "10    0.000000               0.00000                0.00000               \n",
       "11    3.122500               5.37640                4.13040               \n",
       "12    0.381840               5.82300                0.00000               \n",
       "13    0.000000               0.00000                0.00000               \n",
       "14    0.000000               0.00000                0.00000               \n",
       "15    0.000000               0.00000                0.00000               \n",
       "16    0.000000               0.00000                0.00000               \n",
       "17    0.000000               0.00000                0.00000               \n",
       "18    0.000000               0.00000                2.47900               \n",
       "19    0.956060               0.00000                0.00000               \n",
       "20    2.718300               0.00000                3.27560               \n",
       "21    0.034216               0.25942                0.00000               \n",
       "22    0.332280               0.00000                0.00000               \n",
       "23    4.901700               0.00000                0.00000               \n",
       "24    0.000000               0.00000                0.00000               \n",
       "25    0.969380               0.00000                0.00000               \n",
       "26    0.000000               0.00000                0.00000               \n",
       "27    5.286000               0.00000                0.00000               \n",
       "28    1.926000               0.43829                0.00000               \n",
       "29    3.296500               0.00000                0.00000               \n",
       "30    0.000000               0.00000                0.00000               \n",
       "⋮     ⋮                      ⋮                      ⋮                     \n",
       "21784 0.000000               0.00000                0.000000              \n",
       "21785 0.057970               0.56852                3.308900              \n",
       "21786 0.000000               0.00000                0.000000              \n",
       "21787 0.000000               0.00000                0.000000              \n",
       "21788 2.807800               0.00000                0.000000              \n",
       "21789 0.000000               0.00000                0.000000              \n",
       "21790 0.000000               0.00000                0.000000              \n",
       "21791 0.000000               0.00000                0.000000              \n",
       "21792 0.000000               0.00000                0.000000              \n",
       "21793 0.044044               1.14270                0.104340              \n",
       "21794 0.000000               0.00000                0.000000              \n",
       "21795 0.000000               0.00000                0.000000              \n",
       "21796 0.000000               0.00000                0.059355              \n",
       "21797 0.018634               0.00000                1.460000              \n",
       "21798 0.000000               0.00000                0.753600              \n",
       "21799 3.154600               0.00000                0.000000              \n",
       "21800 0.000000               0.00000                1.394000              \n",
       "21801 0.000000               0.00000                0.000000              \n",
       "21802 0.000000               4.39710                0.000000              \n",
       "21803 2.017200               0.00000                4.216400              \n",
       "21804 0.871840               0.00000                4.634800              \n",
       "21805 0.000000               0.00000                0.000000              \n",
       "21806 0.000000               0.00000                0.000000              \n",
       "21807 0.000000               0.00000                0.000000              \n",
       "21808 1.201600               0.36289                0.097611              \n",
       "21809 0.063503               1.08810                0.067639              \n",
       "21810 0.051024               0.85599                0.000000              \n",
       "21811 0.605020               0.00000                5.292800              \n",
       "21812 0.000000               0.85679                0.000000              \n",
       "21813 0.000000               0.00000                0.000000              \n",
       "      HN26_P25_C09_S129_comb ⋯ HNSCC20_P3_B10_S22_comb\n",
       "1     0.000000               ⋯ 0.63320                \n",
       "2     0.000000               ⋯ 0.00000                \n",
       "3     0.000000               ⋯ 0.00000                \n",
       "4     0.000000               ⋯ 0.00000                \n",
       "5     0.000000               ⋯ 0.00000                \n",
       "6     1.125000               ⋯ 0.31150                \n",
       "7     0.000000               ⋯ 0.00000                \n",
       "8     0.000000               ⋯ 5.18090                \n",
       "9     0.000000               ⋯ 0.00000                \n",
       "10    0.000000               ⋯ 0.00000                \n",
       "11    0.000000               ⋯ 0.00000                \n",
       "12    0.000000               ⋯ 0.00000                \n",
       "13    0.000000               ⋯ 0.00000                \n",
       "14    2.824400               ⋯ 0.00000                \n",
       "15    0.000000               ⋯ 0.00000                \n",
       "16    0.000000               ⋯ 0.00000                \n",
       "17    0.000000               ⋯ 0.00000                \n",
       "18    0.000000               ⋯ 0.00000                \n",
       "19    0.000000               ⋯ 0.00000                \n",
       "20    0.000000               ⋯ 4.33260                \n",
       "21    0.027154               ⋯ 0.08134                \n",
       "22    0.000000               ⋯ 0.00000                \n",
       "23    4.569300               ⋯ 4.16740                \n",
       "24    0.000000               ⋯ 0.00000                \n",
       "25    0.000000               ⋯ 1.74670                \n",
       "26    0.113700               ⋯ 0.28451                \n",
       "27    0.000000               ⋯ 5.32560                \n",
       "28    0.000000               ⋯ 0.11103                \n",
       "29    0.000000               ⋯ 2.93790                \n",
       "30    0.000000               ⋯ 2.28040                \n",
       "⋮     ⋮                      ⋱ ⋮                      \n",
       "21784 0.000000               ⋯ 0.000000               \n",
       "21785 0.133560               ⋯ 0.150560               \n",
       "21786 0.000000               ⋯ 0.000000               \n",
       "21787 0.000000               ⋯ 3.177900               \n",
       "21788 0.000000               ⋯ 2.427300               \n",
       "21789 0.000000               ⋯ 0.000000               \n",
       "21790 0.000000               ⋯ 3.225100               \n",
       "21791 0.000000               ⋯ 0.000000               \n",
       "21792 0.000000               ⋯ 0.000000               \n",
       "21793 0.201630               ⋯ 2.539000               \n",
       "21794 0.000000               ⋯ 0.000000               \n",
       "21795 0.000000               ⋯ 0.000000               \n",
       "21796 0.000000               ⋯ 0.000000               \n",
       "21797 0.000000               ⋯ 0.000000               \n",
       "21798 0.000000               ⋯ 0.574340               \n",
       "21799 0.000000               ⋯ 0.227740               \n",
       "21800 0.237560               ⋯ 0.070389               \n",
       "21801 0.000000               ⋯ 0.000000               \n",
       "21802 4.787500               ⋯ 1.000700               \n",
       "21803 0.000000               ⋯ 2.346200               \n",
       "21804 0.000000               ⋯ 1.551400               \n",
       "21805 0.000000               ⋯ 3.049100               \n",
       "21806 0.000000               ⋯ 0.000000               \n",
       "21807 0.000000               ⋯ 0.709290               \n",
       "21808 0.062122               ⋯ 1.441500               \n",
       "21809 0.032806               ⋯ 0.000000               \n",
       "21810 0.092207               ⋯ 0.737250               \n",
       "21811 0.000000               ⋯ 3.382800               \n",
       "21812 0.017209               ⋯ 0.107020               \n",
       "21813 0.000000               ⋯ 2.233300               \n",
       "      HNSCC20_P13_B11_S215_comb HNSCC20_P3_C08_S32_comb\n",
       "1     1.225900                  1.37740                \n",
       "2     1.064200                  0.00000                \n",
       "3     0.000000                  0.00000                \n",
       "4     0.000000                  0.00000                \n",
       "5     0.000000                  0.00000                \n",
       "6     5.735100                  0.00000                \n",
       "7     0.000000                  0.00000                \n",
       "8     3.655200                  5.05750                \n",
       "9     0.000000                  0.00000                \n",
       "10    0.000000                  0.00000                \n",
       "11    2.040500                  3.31510                \n",
       "12    3.939700                  3.80000                \n",
       "13    0.000000                  0.00000                \n",
       "14    0.000000                  0.00000                \n",
       "15    0.000000                  0.00000                \n",
       "16    0.000000                  0.00000                \n",
       "17    0.000000                  0.00000                \n",
       "18    0.000000                  0.00000                \n",
       "19    0.000000                  0.00000                \n",
       "20    2.992600                  3.47310                \n",
       "21    0.063503                  0.39177                \n",
       "22    0.000000                  3.80050                \n",
       "23    3.405400                  5.66740                \n",
       "24    0.000000                  0.00000                \n",
       "25    0.000000                  0.00000                \n",
       "26    0.000000                  0.00000                \n",
       "27    4.501500                  3.39790                \n",
       "28    0.000000                  0.11237                \n",
       "29    2.835300                  3.82950                \n",
       "30    0.783250                  0.00000                \n",
       "⋮     ⋮                         ⋮                      \n",
       "21784 0.00000                   0.000000               \n",
       "21785 1.31320                   0.092207               \n",
       "21786 0.00000                   0.000000               \n",
       "21787 2.18210                   2.527100               \n",
       "21788 1.99750                   0.000000               \n",
       "21789 0.00000                   0.000000               \n",
       "21790 0.00000                   0.000000               \n",
       "21791 0.00000                   0.000000               \n",
       "21792 0.85439                   3.412000               \n",
       "21793 0.20914                   0.186500               \n",
       "21794 0.00000                   0.000000               \n",
       "21795 0.00000                   0.000000               \n",
       "21796 0.00000                   0.000000               \n",
       "21797 0.00000                   0.000000               \n",
       "21798 0.59932                   0.000000               \n",
       "21799 2.57750                   0.278580               \n",
       "21800 0.00000                   0.000000               \n",
       "21801 0.00000                   0.000000               \n",
       "21802 0.00000                   0.000000               \n",
       "21803 2.06630                   0.000000               \n",
       "21804 2.88520                   2.122000               \n",
       "21805 4.54920                   0.000000               \n",
       "21806 0.00000                   0.000000               \n",
       "21807 0.00000                   0.000000               \n",
       "21808 0.00000                   0.041243               \n",
       "21809 0.20163                   0.000000               \n",
       "21810 0.00000                   0.000000               \n",
       "21811 1.00070                   2.524300               \n",
       "21812 0.57531                   0.172490               \n",
       "21813 1.68080                   0.000000               \n",
       "      HNSCC17_P4_H03_S183_comb HNSCC20_P3_F09_S69_comb HNSCC17_P4_G12_S180_comb\n",
       "1     0.00000                  0.000000                0.00000                 \n",
       "2     0.00000                  0.000000                0.00000                 \n",
       "3     0.00000                  0.000000                0.00000                 \n",
       "4     0.00000                  0.000000                0.00000                 \n",
       "5     0.00000                  0.000000                0.00000                 \n",
       "6     0.00000                  0.000000                0.00000                 \n",
       "7     0.00000                  0.000000                0.00000                 \n",
       "8     0.00000                  2.688900                0.00000                 \n",
       "9     0.00000                  0.000000                0.00000                 \n",
       "10    0.00000                  0.000000                0.00000                 \n",
       "11    4.38080                  0.000000                0.00000                 \n",
       "12    0.00000                  0.000000                0.00000                 \n",
       "13    0.00000                  0.000000                0.00000                 \n",
       "14    0.00000                  0.000000                0.00000                 \n",
       "15    0.00000                  0.000000                0.00000                 \n",
       "16    0.00000                  0.000000                0.00000                 \n",
       "17    0.00000                  0.000000                0.00000                 \n",
       "18    0.00000                  0.286880                0.00000                 \n",
       "19    0.00000                  0.000000                0.00000                 \n",
       "20    0.00000                  0.000000                0.00000                 \n",
       "21    0.02148                  1.144700                0.14405                 \n",
       "22    5.09490                  0.000000                5.41960                 \n",
       "23    4.69760                  3.667100                0.00000                 \n",
       "24    0.00000                  0.000000                0.00000                 \n",
       "25    3.19870                  2.109400                1.95830                 \n",
       "26    0.00000                  0.178870                0.00000                 \n",
       "27    0.00000                  7.205100                4.60440                 \n",
       "28    0.00000                  0.066261                0.15186                 \n",
       "29    4.95510                  4.196400                0.00000                 \n",
       "30    0.00000                  0.000000                2.09390                 \n",
       "⋮     ⋮                        ⋮                       ⋮                       \n",
       "21784 0.000000                 2.641100                0.00000                 \n",
       "21785 0.000000                 0.459430                0.27023                 \n",
       "21786 0.000000                 0.000000                0.00000                 \n",
       "21787 0.000000                 0.000000                0.00000                 \n",
       "21788 0.000000                 1.760400                0.00000                 \n",
       "21789 0.000000                 0.000000                0.00000                 \n",
       "21790 0.000000                 0.000000                0.00000                 \n",
       "21791 0.000000                 0.000000                0.00000                 \n",
       "21792 0.000000                 3.296500                0.00000                 \n",
       "21793 0.000000                 0.000000                0.42653                 \n",
       "21794 0.000000                 0.000000                0.00000                 \n",
       "21795 0.000000                 0.000000                0.00000                 \n",
       "21796 0.000000                 0.000000                0.00000                 \n",
       "21797 0.000000                 0.000000                0.00000                 \n",
       "21798 0.000000                 0.310340                0.00000                 \n",
       "21799 0.000000                 1.983300                0.00000                 \n",
       "21800 0.000000                 0.000000                0.00000                 \n",
       "21801 0.000000                 0.000000                0.00000                 \n",
       "21802 0.000000                 0.000000                2.25850                 \n",
       "21803 4.277300                 0.000000                0.00000                 \n",
       "21804 0.000000                 0.000000                0.00000                 \n",
       "21805 4.535600                 0.000000                0.00000                 \n",
       "21806 0.000000                 0.000000                0.00000                 \n",
       "21807 0.000000                 0.000000                0.00000                 \n",
       "21808 0.012926                 0.606920                4.18860                 \n",
       "21809 0.000000                 0.000000                0.39835                 \n",
       "21810 0.037031                 0.039840                0.25459                 \n",
       "21811 0.000000                 0.677170                0.75275                 \n",
       "21812 0.000000                 1.017900                0.00000                 \n",
       "21813 0.000000                 0.071763                0.00000                 \n",
       "      HNSCC20_P13_C05_S221_comb HNSCC17_P4_C12_S132_comb\n",
       "1     0.00000                   0.000000                \n",
       "2     0.00000                   0.000000                \n",
       "3     0.00000                   0.000000                \n",
       "4     0.00000                   0.000000                \n",
       "5     0.00000                   0.000000                \n",
       "6     0.00000                   0.042644                \n",
       "7     0.00000                   0.000000                \n",
       "8     5.08770                   1.811100                \n",
       "9     0.00000                   0.000000                \n",
       "10    0.00000                   0.000000                \n",
       "11    0.00000                   3.652800                \n",
       "12    0.00000                   2.802200                \n",
       "13    0.00000                   0.000000                \n",
       "14    0.00000                   0.000000                \n",
       "15    0.00000                   0.000000                \n",
       "16    0.00000                   0.000000                \n",
       "17    0.00000                   0.000000                \n",
       "18    0.00000                   0.000000                \n",
       "19    0.00000                   2.310000                \n",
       "20    0.00000                   0.000000                \n",
       "21    2.17540                   0.014355                \n",
       "22    0.00000                   4.338900                \n",
       "23    0.00000                   4.172200                \n",
       "24    0.00000                   0.000000                \n",
       "25    0.00000                   0.000000                \n",
       "26    0.00000                   0.000000                \n",
       "27    2.36740                   0.000000                \n",
       "28    0.25822                   3.598200                \n",
       "29    0.00000                   0.000000                \n",
       "30    2.29100                   0.000000                \n",
       "⋮     ⋮                         ⋮                       \n",
       "21784 0.00000                   0.000000                \n",
       "21785 0.61070                   0.028569                \n",
       "21786 0.00000                   0.000000                \n",
       "21787 0.00000                   0.000000                \n",
       "21788 4.98220                   0.000000                \n",
       "21789 0.00000                   0.000000                \n",
       "21790 4.86800                   0.000000                \n",
       "21791 0.35952                   0.000000                \n",
       "21792 0.00000                   0.000000                \n",
       "21793 0.21164                   0.000000                \n",
       "21794 0.00000                   0.000000                \n",
       "21795 0.00000                   0.000000                \n",
       "21796 0.00000                   0.000000                \n",
       "21797 0.00000                   0.000000                \n",
       "21798 2.11440                   0.000000                \n",
       "21799 0.00000                   0.000000                \n",
       "21800 3.09070                   0.821300                \n",
       "21801 0.00000                   0.000000                \n",
       "21802 0.48954                   0.000000                \n",
       "21803 0.00000                   3.737300                \n",
       "21804 0.00000                   0.101650                \n",
       "21805 0.00000                   3.473700                \n",
       "21806 0.00000                   0.000000                \n",
       "21807 0.00000                   0.000000                \n",
       "21808 0.24732                   0.000000                \n",
       "21809 0.74674                   0.000000                \n",
       "21810 0.31846                   2.106300                \n",
       "21811 0.00000                   4.055700                \n",
       "21812 0.00000                   0.000000                \n",
       "21813 0.00000                   0.000000                \n",
       "      HNSCC20_P3_H08_S92_comb HNSCC20_P3_G06_S78_comb\n",
       "1     2.99960                 0.00000                \n",
       "2     0.00000                 0.00000                \n",
       "3     0.00000                 0.00000                \n",
       "4     0.00000                 0.00000                \n",
       "5     0.00000                 0.00000                \n",
       "6     0.00000                 3.40600                \n",
       "7     0.00000                 0.00000                \n",
       "8     3.83700                 4.34800                \n",
       "9     0.00000                 0.00000                \n",
       "10    0.00000                 0.00000                \n",
       "11    4.07110                 0.00000                \n",
       "12    0.00000                 0.13093                \n",
       "13    0.00000                 0.00000                \n",
       "14    0.00000                 0.00000                \n",
       "15    0.00000                 0.00000                \n",
       "16    0.00000                 0.00000                \n",
       "17    0.00000                 0.00000                \n",
       "18    0.00000                 0.00000                \n",
       "19    0.00000                 0.00000                \n",
       "20    0.59455                 0.38736                \n",
       "21    0.10702                 0.10030                \n",
       "22    0.00000                 0.00000                \n",
       "23    6.25820                 5.66890                \n",
       "24    0.00000                 0.00000                \n",
       "25    2.82780                 0.00000                \n",
       "26    0.00000                 0.00000                \n",
       "27    5.82340                 4.35730                \n",
       "28    3.55880                 3.56660                \n",
       "29    2.30920                 2.26090                \n",
       "30    1.29870                 0.00000                \n",
       "⋮     ⋮                       ⋮                      \n",
       "21784 0.00000                 0.000000               \n",
       "21785 2.85160                 0.125650               \n",
       "21786 0.00000                 0.000000               \n",
       "21787 3.32380                 0.000000               \n",
       "21788 3.75320                 0.000000               \n",
       "21789 0.00000                 0.000000               \n",
       "21790 0.00000                 0.000000               \n",
       "21791 0.00000                 0.000000               \n",
       "21792 0.00000                 0.000000               \n",
       "21793 3.66050                 0.341420               \n",
       "21794 0.00000                 0.000000               \n",
       "21795 0.00000                 0.000000               \n",
       "21796 0.00000                 0.000000               \n",
       "21797 0.00000                 0.000000               \n",
       "21798 1.77060                 0.000000               \n",
       "21799 0.00000                 0.000000               \n",
       "21800 0.00000                 0.000000               \n",
       "21801 0.00000                 0.000000               \n",
       "21802 3.78200                 0.000000               \n",
       "21803 0.00000                 0.000000               \n",
       "21804 3.59690                 0.000000               \n",
       "21805 0.00000                 0.000000               \n",
       "21806 0.00000                 0.000000               \n",
       "21807 0.00000                 0.000000               \n",
       "21808 0.15704                 0.034216               \n",
       "21809 0.23634                 0.000000               \n",
       "21810 0.29160                 0.111030               \n",
       "21811 3.73420                 0.000000               \n",
       "21812 0.00000                 0.000000               \n",
       "21813 0.00000                 0.000000               "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "df_Puram"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 5,
   "id": "e557f109",
   "metadata": {},
   "outputs": [],
   "source": [
    "df_TCGA <- read.table(\"/home/cke/Puram/TCGA-HNSC.htseq_counts_exp2.tsv\",sep='\\t',header=TRUE)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 6,
   "id": "cea09399",
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A data.frame: 60483 × 547</caption>\n",
       "<thead>\n",
       "\t<tr><th scope=col>Ensembl_ID</th><th scope=col>TCGA.BB.4224.01A</th><th scope=col>TCGA.H7.7774.01A</th><th scope=col>TCGA.CV.6943.01A</th><th scope=col>TCGA.CN.5374.01A</th><th scope=col>TCGA.CQ.6227.01A</th><th scope=col>TCGA.CV.6959.01A</th><th scope=col>TCGA.F7.A61V.01A</th><th scope=col>TCGA.CV.7413.01A</th><th scope=col>TCGA.CV.7247.01A</th><th scope=col>⋯</th><th scope=col>TCGA.CV.6960.11A</th><th scope=col>TCGA.CV.A464.01A</th><th scope=col>TCGA.C9.A47Z.01A</th><th scope=col>TCGA.CN.6010.01A</th><th scope=col>TCGA.WA.A7GZ.11A</th><th scope=col>TCGA.CV.7235.01A</th><th scope=col>TCGA.CX.7086.01A</th><th scope=col>TCGA.CV.6935.11A</th><th scope=col>TCGA.P3.A6SW.01A</th><th scope=col>TCGA.HD.A6HZ.01A</th></tr>\n",
       "\t<tr><th scope=col>&lt;chr&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>⋯</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><td>ENSG00000000003</td><td>2237</td><td> 2740</td><td> 2686</td><td> 2086</td><td>10167</td><td> 1154</td><td>1978</td><td> 1930</td><td> 1066</td><td>⋯</td><td>3340</td><td>  929</td><td>1707</td><td> 2218</td><td>2537</td><td>  492</td><td> 2741</td><td> 8492</td><td>  770</td><td> 923</td></tr>\n",
       "\t<tr><td>ENSG00000000005</td><td>   2</td><td>    0</td><td>    0</td><td>    1</td><td>    9</td><td>    6</td><td>   1</td><td>    1</td><td>    1</td><td>⋯</td><td>   0</td><td>    2</td><td>   0</td><td>    0</td><td>  41</td><td>    0</td><td>    0</td><td>    3</td><td>    1</td><td>   0</td></tr>\n",
       "\t<tr><td>ENSG00000000419</td><td>1606</td><td> 1691</td><td> 1649</td><td> 2333</td><td> 3021</td><td> 2766</td><td>1762</td><td> 1668</td><td> 1760</td><td>⋯</td><td>1388</td><td> 2332</td><td>1926</td><td> 1574</td><td>1171</td><td>  976</td><td> 1952</td><td> 1578</td><td> 1569</td><td>1183</td></tr>\n",
       "\t<tr><td>ENSG00000000457</td><td>1063</td><td>  803</td><td>  917</td><td> 1288</td><td>  537</td><td>  527</td><td> 482</td><td>  671</td><td>  600</td><td>⋯</td><td> 608</td><td>  472</td><td> 410</td><td>  852</td><td> 557</td><td>  376</td><td> 1003</td><td>  818</td><td>  620</td><td> 607</td></tr>\n",
       "\t<tr><td>ENSG00000000460</td><td>1208</td><td>  317</td><td>  402</td><td> 1105</td><td>  459</td><td>  747</td><td> 331</td><td>  476</td><td>  874</td><td>⋯</td><td> 206</td><td>  386</td><td> 210</td><td>  729</td><td> 127</td><td>  363</td><td> 1103</td><td>  281</td><td>  591</td><td> 344</td></tr>\n",
       "\t<tr><td>ENSG00000000938</td><td> 256</td><td>  330</td><td> 1535</td><td>  639</td><td>  362</td><td>  906</td><td> 147</td><td>  477</td><td>  204</td><td>⋯</td><td> 304</td><td>  331</td><td> 134</td><td>  550</td><td> 165</td><td>  488</td><td>  214</td><td>  419</td><td>  462</td><td> 925</td></tr>\n",
       "\t<tr><td>ENSG00000000971</td><td> 177</td><td> 5472</td><td>15358</td><td> 5565</td><td> 6963</td><td>12856</td><td> 793</td><td> 3669</td><td> 2791</td><td>⋯</td><td>6363</td><td> 7799</td><td>1264</td><td> 5558</td><td>4651</td><td> 5178</td><td> 1809</td><td> 7368</td><td> 2082</td><td>2482</td></tr>\n",
       "\t<tr><td>ENSG00000001036</td><td>2371</td><td> 2316</td><td> 3490</td><td> 2065</td><td> 4883</td><td> 6120</td><td>2364</td><td> 3366</td><td> 1837</td><td>⋯</td><td>1242</td><td> 3028</td><td>1356</td><td> 2921</td><td> 647</td><td> 2138</td><td> 2639</td><td> 1355</td><td> 1603</td><td>1769</td></tr>\n",
       "\t<tr><td>ENSG00000001084</td><td>2741</td><td> 8370</td><td> 4671</td><td> 2902</td><td> 3140</td><td> 7448</td><td>2827</td><td> 2324</td><td> 9779</td><td>⋯</td><td>2100</td><td> 2494</td><td>3710</td><td> 8749</td><td>3029</td><td>20007</td><td>13623</td><td> 2276</td><td>31675</td><td>3949</td></tr>\n",
       "\t<tr><td>ENSG00000001167</td><td>2515</td><td>  816</td><td> 2080</td><td> 1777</td><td> 2448</td><td> 3527</td><td>1159</td><td> 1459</td><td> 1916</td><td>⋯</td><td>1369</td><td> 1711</td><td>1671</td><td> 1596</td><td> 848</td><td> 4131</td><td> 2530</td><td> 1583</td><td> 1473</td><td> 899</td></tr>\n",
       "\t<tr><td>ENSG00000001460</td><td>1273</td><td>  455</td><td>  686</td><td>  504</td><td> 1730</td><td>  975</td><td>1237</td><td> 1624</td><td>  931</td><td>⋯</td><td> 666</td><td>  972</td><td> 611</td><td> 1434</td><td> 303</td><td>  411</td><td> 1662</td><td>  619</td><td>  534</td><td> 956</td></tr>\n",
       "\t<tr><td>ENSG00000001461</td><td>1036</td><td> 2173</td><td> 2877</td><td> 2530</td><td> 4127</td><td> 3187</td><td>1369</td><td> 2721</td><td> 3503</td><td>⋯</td><td>2467</td><td> 2771</td><td>1106</td><td> 5552</td><td>2067</td><td>  948</td><td> 3134</td><td> 2994</td><td> 1441</td><td>1009</td></tr>\n",
       "\t<tr><td>ENSG00000001497</td><td>4205</td><td> 2281</td><td> 3950</td><td> 2812</td><td> 1656</td><td> 3916</td><td>2318</td><td> 2881</td><td> 4760</td><td>⋯</td><td>1974</td><td> 2010</td><td>2556</td><td> 3471</td><td>1060</td><td> 4242</td><td> 2017</td><td> 2516</td><td> 1597</td><td>2057</td></tr>\n",
       "\t<tr><td>ENSG00000001561</td><td>  36</td><td>   71</td><td>  352</td><td>  542</td><td>  364</td><td>  305</td><td>  88</td><td>   29</td><td>  305</td><td>⋯</td><td> 116</td><td>  108</td><td>  30</td><td>  484</td><td>1045</td><td>   84</td><td>  359</td><td>  282</td><td>   95</td><td> 166</td></tr>\n",
       "\t<tr><td>ENSG00000001617</td><td>5270</td><td>14807</td><td>10608</td><td>10675</td><td> 9176</td><td> 6871</td><td>3595</td><td> 6713</td><td> 4538</td><td>⋯</td><td>9900</td><td> 5209</td><td>8838</td><td> 6240</td><td>4345</td><td> 5266</td><td> 4678</td><td>14400</td><td> 7338</td><td>3311</td></tr>\n",
       "\t<tr><td>ENSG00000001626</td><td>  22</td><td>   51</td><td>    2</td><td>   10</td><td>    0</td><td>    2</td><td> 214</td><td>   14</td><td>    6</td><td>⋯</td><td> 261</td><td>    0</td><td>   1</td><td>  313</td><td> 119</td><td>    2</td><td>   23</td><td>  316</td><td>    1</td><td>   4</td></tr>\n",
       "\t<tr><td>ENSG00000001629</td><td>2033</td><td> 2394</td><td> 3963</td><td> 2046</td><td> 4013</td><td> 4695</td><td>1240</td><td> 3258</td><td>37154</td><td>⋯</td><td>2642</td><td> 2266</td><td>2151</td><td> 4424</td><td>1823</td><td> 2794</td><td> 4224</td><td> 2438</td><td> 1522</td><td>2949</td></tr>\n",
       "\t<tr><td>ENSG00000001630</td><td>  30</td><td>  533</td><td>  340</td><td>  221</td><td>  258</td><td>  764</td><td>  89</td><td>  268</td><td> 3230</td><td>⋯</td><td> 623</td><td>  142</td><td> 170</td><td>  836</td><td> 218</td><td>  801</td><td>  841</td><td>  564</td><td>  113</td><td> 247</td></tr>\n",
       "\t<tr><td>ENSG00000001631</td><td>1474</td><td>  928</td><td> 1249</td><td> 1364</td><td> 1651</td><td> 1884</td><td>1175</td><td> 1797</td><td>16307</td><td>⋯</td><td>1201</td><td> 1378</td><td>1176</td><td> 2638</td><td>1335</td><td> 1239</td><td> 2773</td><td> 1349</td><td>  846</td><td>1741</td></tr>\n",
       "\t<tr><td>ENSG00000002016</td><td> 956</td><td>  144</td><td>  276</td><td>  313</td><td>  290</td><td>  389</td><td> 170</td><td>  274</td><td>  571</td><td>⋯</td><td> 258</td><td>  316</td><td> 263</td><td>  335</td><td> 471</td><td>  176</td><td>  594</td><td>  166</td><td>  274</td><td> 534</td></tr>\n",
       "\t<tr><td>ENSG00000002079</td><td>  71</td><td>    5</td><td>   15</td><td>   13</td><td>   57</td><td>   57</td><td>   9</td><td>   26</td><td>  196</td><td>⋯</td><td>   2</td><td>    8</td><td>  46</td><td>   27</td><td>   7</td><td>    9</td><td>   48</td><td>    4</td><td>    3</td><td>  70</td></tr>\n",
       "\t<tr><td>ENSG00000002330</td><td>2176</td><td> 1469</td><td> 1792</td><td> 1454</td><td> 4945</td><td> 2618</td><td>2170</td><td> 2109</td><td> 1465</td><td>⋯</td><td> 852</td><td> 2035</td><td>1032</td><td> 1999</td><td> 827</td><td> 1884</td><td> 1740</td><td> 1795</td><td> 1622</td><td> 804</td></tr>\n",
       "\t<tr><td>ENSG00000002549</td><td>1761</td><td>11512</td><td>23733</td><td> 2595</td><td> 6249</td><td>14539</td><td>1664</td><td> 3509</td><td> 4709</td><td>⋯</td><td>2942</td><td> 8907</td><td>4001</td><td> 3977</td><td>2302</td><td>14008</td><td> 7817</td><td> 4122</td><td> 2865</td><td>5146</td></tr>\n",
       "\t<tr><td>ENSG00000002586</td><td>6575</td><td> 6882</td><td>18744</td><td> 5821</td><td>16307</td><td> 9342</td><td>6421</td><td>23114</td><td>14804</td><td>⋯</td><td>7883</td><td>21783</td><td>7725</td><td>15481</td><td>7301</td><td>14532</td><td> 3594</td><td>11525</td><td> 8249</td><td>5859</td></tr>\n",
       "\t<tr><td>ENSG00000002587</td><td> 364</td><td>  308</td><td>  963</td><td>  688</td><td> 1678</td><td> 1126</td><td> 126</td><td>  332</td><td>  594</td><td>⋯</td><td>1398</td><td>  164</td><td> 382</td><td>  598</td><td> 329</td><td>  149</td><td> 1299</td><td> 4190</td><td>  254</td><td> 296</td></tr>\n",
       "\t<tr><td>ENSG00000002726</td><td> 134</td><td>  308</td><td>  547</td><td>  127</td><td>  286</td><td>  102</td><td> 276</td><td>  657</td><td>   24</td><td>⋯</td><td>  23</td><td>  263</td><td> 427</td><td>  174</td><td>   6</td><td>   23</td><td>  130</td><td> 1465</td><td>   37</td><td>  53</td></tr>\n",
       "\t<tr><td>ENSG00000002745</td><td> 194</td><td>   73</td><td>   19</td><td>    7</td><td>   10</td><td>   26</td><td>  11</td><td>   79</td><td>   16</td><td>⋯</td><td>  10</td><td>    6</td><td>  19</td><td>   21</td><td>   6</td><td>    7</td><td>   21</td><td>   13</td><td>    2</td><td>   4</td></tr>\n",
       "\t<tr><td>ENSG00000002746</td><td> 116</td><td>  203</td><td>  226</td><td>   19</td><td>  373</td><td>   90</td><td>  16</td><td>  287</td><td>  199</td><td>⋯</td><td>   9</td><td>  310</td><td>  34</td><td>  361</td><td> 114</td><td>  119</td><td>   46</td><td>   18</td><td>   19</td><td>  24</td></tr>\n",
       "\t<tr><td>ENSG00000002822</td><td>1604</td><td> 1181</td><td> 3040</td><td> 1352</td><td> 2962</td><td> 2329</td><td>1668</td><td> 2469</td><td> 4104</td><td>⋯</td><td>1101</td><td> 1651</td><td>1071</td><td> 1089</td><td> 894</td><td> 4167</td><td> 2871</td><td> 1811</td><td> 1071</td><td> 982</td></tr>\n",
       "\t<tr><td>ENSG00000002834</td><td>8014</td><td> 8810</td><td>25075</td><td>10776</td><td>24041</td><td>30027</td><td>5905</td><td>16055</td><td>28939</td><td>⋯</td><td>7013</td><td>11931</td><td>9429</td><td>12703</td><td>4249</td><td>13417</td><td>10069</td><td>11222</td><td> 8014</td><td>8982</td></tr>\n",
       "\t<tr><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋱</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td></tr>\n",
       "\t<tr><td>ENSGR0000223274</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000223484</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000223511</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000223571</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000223773</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000225661</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000226179</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000227159</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000228410</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000228572</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000229232</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000230542</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000234622</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000234958</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000236017</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000236871</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000237040</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000237531</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000237801</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000263835</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000263980</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000264510</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000264819</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000265658</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000270726</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000275287</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000276543</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000277120</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000280767</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><td>ENSGR0000281849</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A data.frame: 60483 × 547\n",
       "\\begin{tabular}{lllllllllllllllllllll}\n",
       " Ensembl\\_ID & TCGA.BB.4224.01A & TCGA.H7.7774.01A & TCGA.CV.6943.01A & TCGA.CN.5374.01A & TCGA.CQ.6227.01A & TCGA.CV.6959.01A & TCGA.F7.A61V.01A & TCGA.CV.7413.01A & TCGA.CV.7247.01A & ⋯ & TCGA.CV.6960.11A & TCGA.CV.A464.01A & TCGA.C9.A47Z.01A & TCGA.CN.6010.01A & TCGA.WA.A7GZ.11A & TCGA.CV.7235.01A & TCGA.CX.7086.01A & TCGA.CV.6935.11A & TCGA.P3.A6SW.01A & TCGA.HD.A6HZ.01A\\\\\n",
       " <chr> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & ⋯ & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl>\\\\\n",
       "\\hline\n",
       "\t ENSG00000000003 & 2237 &  2740 &  2686 &  2086 & 10167 &  1154 & 1978 &  1930 &  1066 & ⋯ & 3340 &   929 & 1707 &  2218 & 2537 &   492 &  2741 &  8492 &   770 &  923\\\\\n",
       "\t ENSG00000000005 &    2 &     0 &     0 &     1 &     9 &     6 &    1 &     1 &     1 & ⋯ &    0 &     2 &    0 &     0 &   41 &     0 &     0 &     3 &     1 &    0\\\\\n",
       "\t ENSG00000000419 & 1606 &  1691 &  1649 &  2333 &  3021 &  2766 & 1762 &  1668 &  1760 & ⋯ & 1388 &  2332 & 1926 &  1574 & 1171 &   976 &  1952 &  1578 &  1569 & 1183\\\\\n",
       "\t ENSG00000000457 & 1063 &   803 &   917 &  1288 &   537 &   527 &  482 &   671 &   600 & ⋯ &  608 &   472 &  410 &   852 &  557 &   376 &  1003 &   818 &   620 &  607\\\\\n",
       "\t ENSG00000000460 & 1208 &   317 &   402 &  1105 &   459 &   747 &  331 &   476 &   874 & ⋯ &  206 &   386 &  210 &   729 &  127 &   363 &  1103 &   281 &   591 &  344\\\\\n",
       "\t ENSG00000000938 &  256 &   330 &  1535 &   639 &   362 &   906 &  147 &   477 &   204 & ⋯ &  304 &   331 &  134 &   550 &  165 &   488 &   214 &   419 &   462 &  925\\\\\n",
       "\t ENSG00000000971 &  177 &  5472 & 15358 &  5565 &  6963 & 12856 &  793 &  3669 &  2791 & ⋯ & 6363 &  7799 & 1264 &  5558 & 4651 &  5178 &  1809 &  7368 &  2082 & 2482\\\\\n",
       "\t ENSG00000001036 & 2371 &  2316 &  3490 &  2065 &  4883 &  6120 & 2364 &  3366 &  1837 & ⋯ & 1242 &  3028 & 1356 &  2921 &  647 &  2138 &  2639 &  1355 &  1603 & 1769\\\\\n",
       "\t ENSG00000001084 & 2741 &  8370 &  4671 &  2902 &  3140 &  7448 & 2827 &  2324 &  9779 & ⋯ & 2100 &  2494 & 3710 &  8749 & 3029 & 20007 & 13623 &  2276 & 31675 & 3949\\\\\n",
       "\t ENSG00000001167 & 2515 &   816 &  2080 &  1777 &  2448 &  3527 & 1159 &  1459 &  1916 & ⋯ & 1369 &  1711 & 1671 &  1596 &  848 &  4131 &  2530 &  1583 &  1473 &  899\\\\\n",
       "\t ENSG00000001460 & 1273 &   455 &   686 &   504 &  1730 &   975 & 1237 &  1624 &   931 & ⋯ &  666 &   972 &  611 &  1434 &  303 &   411 &  1662 &   619 &   534 &  956\\\\\n",
       "\t ENSG00000001461 & 1036 &  2173 &  2877 &  2530 &  4127 &  3187 & 1369 &  2721 &  3503 & ⋯ & 2467 &  2771 & 1106 &  5552 & 2067 &   948 &  3134 &  2994 &  1441 & 1009\\\\\n",
       "\t ENSG00000001497 & 4205 &  2281 &  3950 &  2812 &  1656 &  3916 & 2318 &  2881 &  4760 & ⋯ & 1974 &  2010 & 2556 &  3471 & 1060 &  4242 &  2017 &  2516 &  1597 & 2057\\\\\n",
       "\t ENSG00000001561 &   36 &    71 &   352 &   542 &   364 &   305 &   88 &    29 &   305 & ⋯ &  116 &   108 &   30 &   484 & 1045 &    84 &   359 &   282 &    95 &  166\\\\\n",
       "\t ENSG00000001617 & 5270 & 14807 & 10608 & 10675 &  9176 &  6871 & 3595 &  6713 &  4538 & ⋯ & 9900 &  5209 & 8838 &  6240 & 4345 &  5266 &  4678 & 14400 &  7338 & 3311\\\\\n",
       "\t ENSG00000001626 &   22 &    51 &     2 &    10 &     0 &     2 &  214 &    14 &     6 & ⋯ &  261 &     0 &    1 &   313 &  119 &     2 &    23 &   316 &     1 &    4\\\\\n",
       "\t ENSG00000001629 & 2033 &  2394 &  3963 &  2046 &  4013 &  4695 & 1240 &  3258 & 37154 & ⋯ & 2642 &  2266 & 2151 &  4424 & 1823 &  2794 &  4224 &  2438 &  1522 & 2949\\\\\n",
       "\t ENSG00000001630 &   30 &   533 &   340 &   221 &   258 &   764 &   89 &   268 &  3230 & ⋯ &  623 &   142 &  170 &   836 &  218 &   801 &   841 &   564 &   113 &  247\\\\\n",
       "\t ENSG00000001631 & 1474 &   928 &  1249 &  1364 &  1651 &  1884 & 1175 &  1797 & 16307 & ⋯ & 1201 &  1378 & 1176 &  2638 & 1335 &  1239 &  2773 &  1349 &   846 & 1741\\\\\n",
       "\t ENSG00000002016 &  956 &   144 &   276 &   313 &   290 &   389 &  170 &   274 &   571 & ⋯ &  258 &   316 &  263 &   335 &  471 &   176 &   594 &   166 &   274 &  534\\\\\n",
       "\t ENSG00000002079 &   71 &     5 &    15 &    13 &    57 &    57 &    9 &    26 &   196 & ⋯ &    2 &     8 &   46 &    27 &    7 &     9 &    48 &     4 &     3 &   70\\\\\n",
       "\t ENSG00000002330 & 2176 &  1469 &  1792 &  1454 &  4945 &  2618 & 2170 &  2109 &  1465 & ⋯ &  852 &  2035 & 1032 &  1999 &  827 &  1884 &  1740 &  1795 &  1622 &  804\\\\\n",
       "\t ENSG00000002549 & 1761 & 11512 & 23733 &  2595 &  6249 & 14539 & 1664 &  3509 &  4709 & ⋯ & 2942 &  8907 & 4001 &  3977 & 2302 & 14008 &  7817 &  4122 &  2865 & 5146\\\\\n",
       "\t ENSG00000002586 & 6575 &  6882 & 18744 &  5821 & 16307 &  9342 & 6421 & 23114 & 14804 & ⋯ & 7883 & 21783 & 7725 & 15481 & 7301 & 14532 &  3594 & 11525 &  8249 & 5859\\\\\n",
       "\t ENSG00000002587 &  364 &   308 &   963 &   688 &  1678 &  1126 &  126 &   332 &   594 & ⋯ & 1398 &   164 &  382 &   598 &  329 &   149 &  1299 &  4190 &   254 &  296\\\\\n",
       "\t ENSG00000002726 &  134 &   308 &   547 &   127 &   286 &   102 &  276 &   657 &    24 & ⋯ &   23 &   263 &  427 &   174 &    6 &    23 &   130 &  1465 &    37 &   53\\\\\n",
       "\t ENSG00000002745 &  194 &    73 &    19 &     7 &    10 &    26 &   11 &    79 &    16 & ⋯ &   10 &     6 &   19 &    21 &    6 &     7 &    21 &    13 &     2 &    4\\\\\n",
       "\t ENSG00000002746 &  116 &   203 &   226 &    19 &   373 &    90 &   16 &   287 &   199 & ⋯ &    9 &   310 &   34 &   361 &  114 &   119 &    46 &    18 &    19 &   24\\\\\n",
       "\t ENSG00000002822 & 1604 &  1181 &  3040 &  1352 &  2962 &  2329 & 1668 &  2469 &  4104 & ⋯ & 1101 &  1651 & 1071 &  1089 &  894 &  4167 &  2871 &  1811 &  1071 &  982\\\\\n",
       "\t ENSG00000002834 & 8014 &  8810 & 25075 & 10776 & 24041 & 30027 & 5905 & 16055 & 28939 & ⋯ & 7013 & 11931 & 9429 & 12703 & 4249 & 13417 & 10069 & 11222 &  8014 & 8982\\\\\n",
       "\t ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋱ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n",
       "\t ENSGR0000223274 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000223484 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000223511 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000223571 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000223773 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000225661 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000226179 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000227159 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000228410 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000228572 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000229232 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000230542 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000234622 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000234958 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000236017 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000236871 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000237040 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000237531 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000237801 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000263835 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000263980 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000264510 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000264819 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000265658 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000270726 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000275287 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000276543 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000277120 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000280767 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\t ENSGR0000281849 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0 & 0\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A data.frame: 60483 × 547\n",
       "\n",
       "| Ensembl_ID &lt;chr&gt; | TCGA.BB.4224.01A &lt;dbl&gt; | TCGA.H7.7774.01A &lt;dbl&gt; | TCGA.CV.6943.01A &lt;dbl&gt; | TCGA.CN.5374.01A &lt;dbl&gt; | TCGA.CQ.6227.01A &lt;dbl&gt; | TCGA.CV.6959.01A &lt;dbl&gt; | TCGA.F7.A61V.01A &lt;dbl&gt; | TCGA.CV.7413.01A &lt;dbl&gt; | TCGA.CV.7247.01A &lt;dbl&gt; | ⋯ ⋯ | TCGA.CV.6960.11A &lt;dbl&gt; | TCGA.CV.A464.01A &lt;dbl&gt; | TCGA.C9.A47Z.01A &lt;dbl&gt; | TCGA.CN.6010.01A &lt;dbl&gt; | TCGA.WA.A7GZ.11A &lt;dbl&gt; | TCGA.CV.7235.01A &lt;dbl&gt; | TCGA.CX.7086.01A &lt;dbl&gt; | TCGA.CV.6935.11A &lt;dbl&gt; | TCGA.P3.A6SW.01A &lt;dbl&gt; | TCGA.HD.A6HZ.01A &lt;dbl&gt; |\n",
       "|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|\n",
       "| ENSG00000000003 | 2237 |  2740 |  2686 |  2086 | 10167 |  1154 | 1978 |  1930 |  1066 | ⋯ | 3340 |   929 | 1707 |  2218 | 2537 |   492 |  2741 |  8492 |   770 |  923 |\n",
       "| ENSG00000000005 |    2 |     0 |     0 |     1 |     9 |     6 |    1 |     1 |     1 | ⋯ |    0 |     2 |    0 |     0 |   41 |     0 |     0 |     3 |     1 |    0 |\n",
       "| ENSG00000000419 | 1606 |  1691 |  1649 |  2333 |  3021 |  2766 | 1762 |  1668 |  1760 | ⋯ | 1388 |  2332 | 1926 |  1574 | 1171 |   976 |  1952 |  1578 |  1569 | 1183 |\n",
       "| ENSG00000000457 | 1063 |   803 |   917 |  1288 |   537 |   527 |  482 |   671 |   600 | ⋯ |  608 |   472 |  410 |   852 |  557 |   376 |  1003 |   818 |   620 |  607 |\n",
       "| ENSG00000000460 | 1208 |   317 |   402 |  1105 |   459 |   747 |  331 |   476 |   874 | ⋯ |  206 |   386 |  210 |   729 |  127 |   363 |  1103 |   281 |   591 |  344 |\n",
       "| ENSG00000000938 |  256 |   330 |  1535 |   639 |   362 |   906 |  147 |   477 |   204 | ⋯ |  304 |   331 |  134 |   550 |  165 |   488 |   214 |   419 |   462 |  925 |\n",
       "| ENSG00000000971 |  177 |  5472 | 15358 |  5565 |  6963 | 12856 |  793 |  3669 |  2791 | ⋯ | 6363 |  7799 | 1264 |  5558 | 4651 |  5178 |  1809 |  7368 |  2082 | 2482 |\n",
       "| ENSG00000001036 | 2371 |  2316 |  3490 |  2065 |  4883 |  6120 | 2364 |  3366 |  1837 | ⋯ | 1242 |  3028 | 1356 |  2921 |  647 |  2138 |  2639 |  1355 |  1603 | 1769 |\n",
       "| ENSG00000001084 | 2741 |  8370 |  4671 |  2902 |  3140 |  7448 | 2827 |  2324 |  9779 | ⋯ | 2100 |  2494 | 3710 |  8749 | 3029 | 20007 | 13623 |  2276 | 31675 | 3949 |\n",
       "| ENSG00000001167 | 2515 |   816 |  2080 |  1777 |  2448 |  3527 | 1159 |  1459 |  1916 | ⋯ | 1369 |  1711 | 1671 |  1596 |  848 |  4131 |  2530 |  1583 |  1473 |  899 |\n",
       "| ENSG00000001460 | 1273 |   455 |   686 |   504 |  1730 |   975 | 1237 |  1624 |   931 | ⋯ |  666 |   972 |  611 |  1434 |  303 |   411 |  1662 |   619 |   534 |  956 |\n",
       "| ENSG00000001461 | 1036 |  2173 |  2877 |  2530 |  4127 |  3187 | 1369 |  2721 |  3503 | ⋯ | 2467 |  2771 | 1106 |  5552 | 2067 |   948 |  3134 |  2994 |  1441 | 1009 |\n",
       "| ENSG00000001497 | 4205 |  2281 |  3950 |  2812 |  1656 |  3916 | 2318 |  2881 |  4760 | ⋯ | 1974 |  2010 | 2556 |  3471 | 1060 |  4242 |  2017 |  2516 |  1597 | 2057 |\n",
       "| ENSG00000001561 |   36 |    71 |   352 |   542 |   364 |   305 |   88 |    29 |   305 | ⋯ |  116 |   108 |   30 |   484 | 1045 |    84 |   359 |   282 |    95 |  166 |\n",
       "| ENSG00000001617 | 5270 | 14807 | 10608 | 10675 |  9176 |  6871 | 3595 |  6713 |  4538 | ⋯ | 9900 |  5209 | 8838 |  6240 | 4345 |  5266 |  4678 | 14400 |  7338 | 3311 |\n",
       "| ENSG00000001626 |   22 |    51 |     2 |    10 |     0 |     2 |  214 |    14 |     6 | ⋯ |  261 |     0 |    1 |   313 |  119 |     2 |    23 |   316 |     1 |    4 |\n",
       "| ENSG00000001629 | 2033 |  2394 |  3963 |  2046 |  4013 |  4695 | 1240 |  3258 | 37154 | ⋯ | 2642 |  2266 | 2151 |  4424 | 1823 |  2794 |  4224 |  2438 |  1522 | 2949 |\n",
       "| ENSG00000001630 |   30 |   533 |   340 |   221 |   258 |   764 |   89 |   268 |  3230 | ⋯ |  623 |   142 |  170 |   836 |  218 |   801 |   841 |   564 |   113 |  247 |\n",
       "| ENSG00000001631 | 1474 |   928 |  1249 |  1364 |  1651 |  1884 | 1175 |  1797 | 16307 | ⋯ | 1201 |  1378 | 1176 |  2638 | 1335 |  1239 |  2773 |  1349 |   846 | 1741 |\n",
       "| ENSG00000002016 |  956 |   144 |   276 |   313 |   290 |   389 |  170 |   274 |   571 | ⋯ |  258 |   316 |  263 |   335 |  471 |   176 |   594 |   166 |   274 |  534 |\n",
       "| ENSG00000002079 |   71 |     5 |    15 |    13 |    57 |    57 |    9 |    26 |   196 | ⋯ |    2 |     8 |   46 |    27 |    7 |     9 |    48 |     4 |     3 |   70 |\n",
       "| ENSG00000002330 | 2176 |  1469 |  1792 |  1454 |  4945 |  2618 | 2170 |  2109 |  1465 | ⋯ |  852 |  2035 | 1032 |  1999 |  827 |  1884 |  1740 |  1795 |  1622 |  804 |\n",
       "| ENSG00000002549 | 1761 | 11512 | 23733 |  2595 |  6249 | 14539 | 1664 |  3509 |  4709 | ⋯ | 2942 |  8907 | 4001 |  3977 | 2302 | 14008 |  7817 |  4122 |  2865 | 5146 |\n",
       "| ENSG00000002586 | 6575 |  6882 | 18744 |  5821 | 16307 |  9342 | 6421 | 23114 | 14804 | ⋯ | 7883 | 21783 | 7725 | 15481 | 7301 | 14532 |  3594 | 11525 |  8249 | 5859 |\n",
       "| ENSG00000002587 |  364 |   308 |   963 |   688 |  1678 |  1126 |  126 |   332 |   594 | ⋯ | 1398 |   164 |  382 |   598 |  329 |   149 |  1299 |  4190 |   254 |  296 |\n",
       "| ENSG00000002726 |  134 |   308 |   547 |   127 |   286 |   102 |  276 |   657 |    24 | ⋯ |   23 |   263 |  427 |   174 |    6 |    23 |   130 |  1465 |    37 |   53 |\n",
       "| ENSG00000002745 |  194 |    73 |    19 |     7 |    10 |    26 |   11 |    79 |    16 | ⋯ |   10 |     6 |   19 |    21 |    6 |     7 |    21 |    13 |     2 |    4 |\n",
       "| ENSG00000002746 |  116 |   203 |   226 |    19 |   373 |    90 |   16 |   287 |   199 | ⋯ |    9 |   310 |   34 |   361 |  114 |   119 |    46 |    18 |    19 |   24 |\n",
       "| ENSG00000002822 | 1604 |  1181 |  3040 |  1352 |  2962 |  2329 | 1668 |  2469 |  4104 | ⋯ | 1101 |  1651 | 1071 |  1089 |  894 |  4167 |  2871 |  1811 |  1071 |  982 |\n",
       "| ENSG00000002834 | 8014 |  8810 | 25075 | 10776 | 24041 | 30027 | 5905 | 16055 | 28939 | ⋯ | 7013 | 11931 | 9429 | 12703 | 4249 | 13417 | 10069 | 11222 |  8014 | 8982 |\n",
       "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋱ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ |\n",
       "| ENSGR0000223274 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000223484 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000223511 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000223571 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000223773 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000225661 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000226179 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000227159 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000228410 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000228572 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000229232 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000230542 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000234622 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000234958 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000236017 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000236871 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000237040 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000237531 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000237801 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000263835 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000263980 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000264510 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000264819 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000265658 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000270726 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000275287 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000276543 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000277120 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000280767 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "| ENSGR0000281849 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |\n",
       "\n"
      ],
      "text/plain": [
       "      Ensembl_ID      TCGA.BB.4224.01A TCGA.H7.7774.01A TCGA.CV.6943.01A\n",
       "1     ENSG00000000003 2237              2740             2686           \n",
       "2     ENSG00000000005    2                 0                0           \n",
       "3     ENSG00000000419 1606              1691             1649           \n",
       "4     ENSG00000000457 1063               803              917           \n",
       "5     ENSG00000000460 1208               317              402           \n",
       "6     ENSG00000000938  256               330             1535           \n",
       "7     ENSG00000000971  177              5472            15358           \n",
       "8     ENSG00000001036 2371              2316             3490           \n",
       "9     ENSG00000001084 2741              8370             4671           \n",
       "10    ENSG00000001167 2515               816             2080           \n",
       "11    ENSG00000001460 1273               455              686           \n",
       "12    ENSG00000001461 1036              2173             2877           \n",
       "13    ENSG00000001497 4205              2281             3950           \n",
       "14    ENSG00000001561   36                71              352           \n",
       "15    ENSG00000001617 5270             14807            10608           \n",
       "16    ENSG00000001626   22                51                2           \n",
       "17    ENSG00000001629 2033              2394             3963           \n",
       "18    ENSG00000001630   30               533              340           \n",
       "19    ENSG00000001631 1474               928             1249           \n",
       "20    ENSG00000002016  956               144              276           \n",
       "21    ENSG00000002079   71                 5               15           \n",
       "22    ENSG00000002330 2176              1469             1792           \n",
       "23    ENSG00000002549 1761             11512            23733           \n",
       "24    ENSG00000002586 6575              6882            18744           \n",
       "25    ENSG00000002587  364               308              963           \n",
       "26    ENSG00000002726  134               308              547           \n",
       "27    ENSG00000002745  194                73               19           \n",
       "28    ENSG00000002746  116               203              226           \n",
       "29    ENSG00000002822 1604              1181             3040           \n",
       "30    ENSG00000002834 8014              8810            25075           \n",
       "⋮     ⋮               ⋮                ⋮                ⋮               \n",
       "60454 ENSGR0000223274 0                0                0               \n",
       "60455 ENSGR0000223484 0                0                0               \n",
       "60456 ENSGR0000223511 0                0                0               \n",
       "60457 ENSGR0000223571 0                0                0               \n",
       "60458 ENSGR0000223773 0                0                0               \n",
       "60459 ENSGR0000225661 0                0                0               \n",
       "60460 ENSGR0000226179 0                0                0               \n",
       "60461 ENSGR0000227159 0                0                0               \n",
       "60462 ENSGR0000228410 0                0                0               \n",
       "60463 ENSGR0000228572 0                0                0               \n",
       "60464 ENSGR0000229232 0                0                0               \n",
       "60465 ENSGR0000230542 0                0                0               \n",
       "60466 ENSGR0000234622 0                0                0               \n",
       "60467 ENSGR0000234958 0                0                0               \n",
       "60468 ENSGR0000236017 0                0                0               \n",
       "60469 ENSGR0000236871 0                0                0               \n",
       "60470 ENSGR0000237040 0                0                0               \n",
       "60471 ENSGR0000237531 0                0                0               \n",
       "60472 ENSGR0000237801 0                0                0               \n",
       "60473 ENSGR0000263835 0                0                0               \n",
       "60474 ENSGR0000263980 0                0                0               \n",
       "60475 ENSGR0000264510 0                0                0               \n",
       "60476 ENSGR0000264819 0                0                0               \n",
       "60477 ENSGR0000265658 0                0                0               \n",
       "60478 ENSGR0000270726 0                0                0               \n",
       "60479 ENSGR0000275287 0                0                0               \n",
       "60480 ENSGR0000276543 0                0                0               \n",
       "60481 ENSGR0000277120 0                0                0               \n",
       "60482 ENSGR0000280767 0                0                0               \n",
       "60483 ENSGR0000281849 0                0                0               \n",
       "      TCGA.CN.5374.01A TCGA.CQ.6227.01A TCGA.CV.6959.01A TCGA.F7.A61V.01A\n",
       "1      2086            10167             1154            1978            \n",
       "2         1                9                6               1            \n",
       "3      2333             3021             2766            1762            \n",
       "4      1288              537              527             482            \n",
       "5      1105              459              747             331            \n",
       "6       639              362              906             147            \n",
       "7      5565             6963            12856             793            \n",
       "8      2065             4883             6120            2364            \n",
       "9      2902             3140             7448            2827            \n",
       "10     1777             2448             3527            1159            \n",
       "11      504             1730              975            1237            \n",
       "12     2530             4127             3187            1369            \n",
       "13     2812             1656             3916            2318            \n",
       "14      542              364              305              88            \n",
       "15    10675             9176             6871            3595            \n",
       "16       10                0                2             214            \n",
       "17     2046             4013             4695            1240            \n",
       "18      221              258              764              89            \n",
       "19     1364             1651             1884            1175            \n",
       "20      313              290              389             170            \n",
       "21       13               57               57               9            \n",
       "22     1454             4945             2618            2170            \n",
       "23     2595             6249            14539            1664            \n",
       "24     5821            16307             9342            6421            \n",
       "25      688             1678             1126             126            \n",
       "26      127              286              102             276            \n",
       "27        7               10               26              11            \n",
       "28       19              373               90              16            \n",
       "29     1352             2962             2329            1668            \n",
       "30    10776            24041            30027            5905            \n",
       "⋮     ⋮                ⋮                ⋮                ⋮               \n",
       "60454 0                0                0                0               \n",
       "60455 0                0                0                0               \n",
       "60456 0                0                0                0               \n",
       "60457 0                0                0                0               \n",
       "60458 0                0                0                0               \n",
       "60459 0                0                0                0               \n",
       "60460 0                0                0                0               \n",
       "60461 0                0                0                0               \n",
       "60462 0                0                0                0               \n",
       "60463 0                0                0                0               \n",
       "60464 0                0                0                0               \n",
       "60465 0                0                0                0               \n",
       "60466 0                0                0                0               \n",
       "60467 0                0                0                0               \n",
       "60468 0                0                0                0               \n",
       "60469 0                0                0                0               \n",
       "60470 0                0                0                0               \n",
       "60471 0                0                0                0               \n",
       "60472 0                0                0                0               \n",
       "60473 0                0                0                0               \n",
       "60474 0                0                0                0               \n",
       "60475 0                0                0                0               \n",
       "60476 0                0                0                0               \n",
       "60477 0                0                0                0               \n",
       "60478 0                0                0                0               \n",
       "60479 0                0                0                0               \n",
       "60480 0                0                0                0               \n",
       "60481 0                0                0                0               \n",
       "60482 0                0                0                0               \n",
       "60483 0                0                0                0               \n",
       "      TCGA.CV.7413.01A TCGA.CV.7247.01A ⋯ TCGA.CV.6960.11A TCGA.CV.A464.01A\n",
       "1      1930             1066            ⋯ 3340               929           \n",
       "2         1                1            ⋯    0                 2           \n",
       "3      1668             1760            ⋯ 1388              2332           \n",
       "4       671              600            ⋯  608               472           \n",
       "5       476              874            ⋯  206               386           \n",
       "6       477              204            ⋯  304               331           \n",
       "7      3669             2791            ⋯ 6363              7799           \n",
       "8      3366             1837            ⋯ 1242              3028           \n",
       "9      2324             9779            ⋯ 2100              2494           \n",
       "10     1459             1916            ⋯ 1369              1711           \n",
       "11     1624              931            ⋯  666               972           \n",
       "12     2721             3503            ⋯ 2467              2771           \n",
       "13     2881             4760            ⋯ 1974              2010           \n",
       "14       29              305            ⋯  116               108           \n",
       "15     6713             4538            ⋯ 9900              5209           \n",
       "16       14                6            ⋯  261                 0           \n",
       "17     3258            37154            ⋯ 2642              2266           \n",
       "18      268             3230            ⋯  623               142           \n",
       "19     1797            16307            ⋯ 1201              1378           \n",
       "20      274              571            ⋯  258               316           \n",
       "21       26              196            ⋯    2                 8           \n",
       "22     2109             1465            ⋯  852              2035           \n",
       "23     3509             4709            ⋯ 2942              8907           \n",
       "24    23114            14804            ⋯ 7883             21783           \n",
       "25      332              594            ⋯ 1398               164           \n",
       "26      657               24            ⋯   23               263           \n",
       "27       79               16            ⋯   10                 6           \n",
       "28      287              199            ⋯    9               310           \n",
       "29     2469             4104            ⋯ 1101              1651           \n",
       "30    16055            28939            ⋯ 7013             11931           \n",
       "⋮     ⋮                ⋮                ⋱ ⋮                ⋮               \n",
       "60454 0                0                ⋯ 0                0               \n",
       "60455 0                0                ⋯ 0                0               \n",
       "60456 0                0                ⋯ 0                0               \n",
       "60457 0                0                ⋯ 0                0               \n",
       "60458 0                0                ⋯ 0                0               \n",
       "60459 0                0                ⋯ 0                0               \n",
       "60460 0                0                ⋯ 0                0               \n",
       "60461 0                0                ⋯ 0                0               \n",
       "60462 0                0                ⋯ 0                0               \n",
       "60463 0                0                ⋯ 0                0               \n",
       "60464 0                0                ⋯ 0                0               \n",
       "60465 0                0                ⋯ 0                0               \n",
       "60466 0                0                ⋯ 0                0               \n",
       "60467 0                0                ⋯ 0                0               \n",
       "60468 0                0                ⋯ 0                0               \n",
       "60469 0                0                ⋯ 0                0               \n",
       "60470 0                0                ⋯ 0                0               \n",
       "60471 0                0                ⋯ 0                0               \n",
       "60472 0                0                ⋯ 0                0               \n",
       "60473 0                0                ⋯ 0                0               \n",
       "60474 0                0                ⋯ 0                0               \n",
       "60475 0                0                ⋯ 0                0               \n",
       "60476 0                0                ⋯ 0                0               \n",
       "60477 0                0                ⋯ 0                0               \n",
       "60478 0                0                ⋯ 0                0               \n",
       "60479 0                0                ⋯ 0                0               \n",
       "60480 0                0                ⋯ 0                0               \n",
       "60481 0                0                ⋯ 0                0               \n",
       "60482 0                0                ⋯ 0                0               \n",
       "60483 0                0                ⋯ 0                0               \n",
       "      TCGA.C9.A47Z.01A TCGA.CN.6010.01A TCGA.WA.A7GZ.11A TCGA.CV.7235.01A\n",
       "1     1707              2218            2537               492           \n",
       "2        0                 0              41                 0           \n",
       "3     1926              1574            1171               976           \n",
       "4      410               852             557               376           \n",
       "5      210               729             127               363           \n",
       "6      134               550             165               488           \n",
       "7     1264              5558            4651              5178           \n",
       "8     1356              2921             647              2138           \n",
       "9     3710              8749            3029             20007           \n",
       "10    1671              1596             848              4131           \n",
       "11     611              1434             303               411           \n",
       "12    1106              5552            2067               948           \n",
       "13    2556              3471            1060              4242           \n",
       "14      30               484            1045                84           \n",
       "15    8838              6240            4345              5266           \n",
       "16       1               313             119                 2           \n",
       "17    2151              4424            1823              2794           \n",
       "18     170               836             218               801           \n",
       "19    1176              2638            1335              1239           \n",
       "20     263               335             471               176           \n",
       "21      46                27               7                 9           \n",
       "22    1032              1999             827              1884           \n",
       "23    4001              3977            2302             14008           \n",
       "24    7725             15481            7301             14532           \n",
       "25     382               598             329               149           \n",
       "26     427               174               6                23           \n",
       "27      19                21               6                 7           \n",
       "28      34               361             114               119           \n",
       "29    1071              1089             894              4167           \n",
       "30    9429             12703            4249             13417           \n",
       "⋮     ⋮                ⋮                ⋮                ⋮               \n",
       "60454 0                0                0                0               \n",
       "60455 0                0                0                0               \n",
       "60456 0                0                0                0               \n",
       "60457 0                0                0                0               \n",
       "60458 0                0                0                0               \n",
       "60459 0                0                0                0               \n",
       "60460 0                0                0                0               \n",
       "60461 0                0                0                0               \n",
       "60462 0                0                0                0               \n",
       "60463 0                0                0                0               \n",
       "60464 0                0                0                0               \n",
       "60465 0                0                0                0               \n",
       "60466 0                0                0                0               \n",
       "60467 0                0                0                0               \n",
       "60468 0                0                0                0               \n",
       "60469 0                0                0                0               \n",
       "60470 0                0                0                0               \n",
       "60471 0                0                0                0               \n",
       "60472 0                0                0                0               \n",
       "60473 0                0                0                0               \n",
       "60474 0                0                0                0               \n",
       "60475 0                0                0                0               \n",
       "60476 0                0                0                0               \n",
       "60477 0                0                0                0               \n",
       "60478 0                0                0                0               \n",
       "60479 0                0                0                0               \n",
       "60480 0                0                0                0               \n",
       "60481 0                0                0                0               \n",
       "60482 0                0                0                0               \n",
       "60483 0                0                0                0               \n",
       "      TCGA.CX.7086.01A TCGA.CV.6935.11A TCGA.P3.A6SW.01A TCGA.HD.A6HZ.01A\n",
       "1      2741             8492              770             923            \n",
       "2         0                3                1               0            \n",
       "3      1952             1578             1569            1183            \n",
       "4      1003              818              620             607            \n",
       "5      1103              281              591             344            \n",
       "6       214              419              462             925            \n",
       "7      1809             7368             2082            2482            \n",
       "8      2639             1355             1603            1769            \n",
       "9     13623             2276            31675            3949            \n",
       "10     2530             1583             1473             899            \n",
       "11     1662              619              534             956            \n",
       "12     3134             2994             1441            1009            \n",
       "13     2017             2516             1597            2057            \n",
       "14      359              282               95             166            \n",
       "15     4678            14400             7338            3311            \n",
       "16       23              316                1               4            \n",
       "17     4224             2438             1522            2949            \n",
       "18      841              564              113             247            \n",
       "19     2773             1349              846            1741            \n",
       "20      594              166              274             534            \n",
       "21       48                4                3              70            \n",
       "22     1740             1795             1622             804            \n",
       "23     7817             4122             2865            5146            \n",
       "24     3594            11525             8249            5859            \n",
       "25     1299             4190              254             296            \n",
       "26      130             1465               37              53            \n",
       "27       21               13                2               4            \n",
       "28       46               18               19              24            \n",
       "29     2871             1811             1071             982            \n",
       "30    10069            11222             8014            8982            \n",
       "⋮     ⋮                ⋮                ⋮                ⋮               \n",
       "60454 0                0                0                0               \n",
       "60455 0                0                0                0               \n",
       "60456 0                0                0                0               \n",
       "60457 0                0                0                0               \n",
       "60458 0                0                0                0               \n",
       "60459 0                0                0                0               \n",
       "60460 0                0                0                0               \n",
       "60461 0                0                0                0               \n",
       "60462 0                0                0                0               \n",
       "60463 0                0                0                0               \n",
       "60464 0                0                0                0               \n",
       "60465 0                0                0                0               \n",
       "60466 0                0                0                0               \n",
       "60467 0                0                0                0               \n",
       "60468 0                0                0                0               \n",
       "60469 0                0                0                0               \n",
       "60470 0                0                0                0               \n",
       "60471 0                0                0                0               \n",
       "60472 0                0                0                0               \n",
       "60473 0                0                0                0               \n",
       "60474 0                0                0                0               \n",
       "60475 0                0                0                0               \n",
       "60476 0                0                0                0               \n",
       "60477 0                0                0                0               \n",
       "60478 0                0                0                0               \n",
       "60479 0                0                0                0               \n",
       "60480 0                0                0                0               \n",
       "60481 0                0                0                0               \n",
       "60482 0                0                0                0               \n",
       "60483 0                0                0                0               "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "df_TCGA"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 7,
   "id": "5b385b94",
   "metadata": {},
   "outputs": [],
   "source": [
    "df_TCGA_t<-t(df_TCGA)\n",
    "colnames(df_TCGA_t)<-df_TCGA_t[1,]\n",
    "df_TCGA_t <- df_TCGA_t[-1,]"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 8,
   "id": "361183bc",
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A matrix: 546 × 60483 of type chr</caption>\n",
       "<thead>\n",
       "\t<tr><th></th><th scope=col>ENSG00000000003</th><th scope=col>ENSG00000000005</th><th scope=col>ENSG00000000419</th><th scope=col>ENSG00000000457</th><th scope=col>ENSG00000000460</th><th scope=col>ENSG00000000938</th><th scope=col>ENSG00000000971</th><th scope=col>ENSG00000001036</th><th scope=col>ENSG00000001084</th><th scope=col>ENSG00000001167</th><th scope=col>⋯</th><th scope=col>ENSGR0000263980</th><th scope=col>ENSGR0000264510</th><th scope=col>ENSGR0000264819</th><th scope=col>ENSGR0000265658</th><th scope=col>ENSGR0000270726</th><th scope=col>ENSGR0000275287</th><th scope=col>ENSGR0000276543</th><th scope=col>ENSGR0000277120</th><th scope=col>ENSGR0000280767</th><th scope=col>ENSGR0000281849</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><th scope=row>TCGA.BB.4224.01A</th><td>   2237</td><td>      2</td><td>   1606</td><td>   1063</td><td>   1208</td><td>    256</td><td>    177</td><td>   2371</td><td>   2741</td><td>   2515</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.H7.7774.01A</th><td>   2740</td><td>      0</td><td>   1691</td><td>    803</td><td>    317</td><td>    330</td><td>   5472</td><td>   2316</td><td>   8370</td><td>    816</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6943.01A</th><td>   2686</td><td>      0</td><td>   1649</td><td>    917</td><td>    402</td><td>   1535</td><td>  15358</td><td>   3490</td><td>   4671</td><td>   2080</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.5374.01A</th><td>  2086 </td><td>     1 </td><td>  2333 </td><td>  1288 </td><td>  1105 </td><td>   639 </td><td>  5565 </td><td>  2065 </td><td>  2902 </td><td>  1777 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.6227.01A</th><td>  10167</td><td>      9</td><td>   3021</td><td>    537</td><td>    459</td><td>    362</td><td>   6963</td><td>   4883</td><td>   3140</td><td>   2448</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6959.01A</th><td>   1154</td><td>      6</td><td>   2766</td><td>    527</td><td>    747</td><td>    906</td><td>  12856</td><td>   6120</td><td>   7448</td><td>   3527</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.F7.A61V.01A</th><td>  1978 </td><td>     1 </td><td>  1762 </td><td>   482 </td><td>   331 </td><td>   147 </td><td>   793 </td><td>  2364 </td><td>  2827 </td><td>  1159 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7413.01A</th><td>   1930</td><td>      1</td><td>   1668</td><td>    671</td><td>    476</td><td>    477</td><td>   3669</td><td>   3366</td><td>   2324</td><td>   1459</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7247.01A</th><td>   1066</td><td>      1</td><td>   1760</td><td>    600</td><td>    874</td><td>    204</td><td>   2791</td><td>   1837</td><td>   9779</td><td>   1916</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.5249.01A</th><td>   2538</td><td>      0</td><td>   1268</td><td>   1066</td><td>    950</td><td>    924</td><td>   5289</td><td>   2584</td><td>   2971</td><td>   2572</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.5331.01A</th><td>   1465</td><td>      0</td><td>   2612</td><td>   1027</td><td>    766</td><td>   1084</td><td>  14982</td><td>   5098</td><td>   7356</td><td>   4672</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.BB.8601.01A</th><td>  1630 </td><td>     1 </td><td>  1227 </td><td>   764 </td><td>   687 </td><td>    42 </td><td>   357 </td><td>  1270 </td><td> 19713 </td><td>  1255 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45W.01A</th><td>   2215</td><td>      0</td><td>   1139</td><td>    526</td><td>    464</td><td>   1024</td><td>   1911</td><td>   1741</td><td>   8343</td><td>   1061</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.7063.01A</th><td>    724</td><td>      0</td><td>   1220</td><td>    461</td><td>    235</td><td>    668</td><td>   4934</td><td>   1323</td><td>   1859</td><td>   1229</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.5373.01A</th><td>    718</td><td>      0</td><td>   1162</td><td>    577</td><td>    232</td><td>    475</td><td>   6444</td><td>   2164</td><td>   2870</td><td>   1650</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45T.01A</th><td>   2120</td><td>      3</td><td>   2252</td><td>    614</td><td>    340</td><td>    700</td><td>   4178</td><td>   1998</td><td>   1845</td><td>   1197</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.HD.A4C1.01A</th><td>  1273 </td><td>     2 </td><td>  1793 </td><td>   646 </td><td>   461 </td><td>   238 </td><td>  4564 </td><td>  1802 </td><td>  2617 </td><td>  1129 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7438.11A</th><td>   4370</td><td>      3</td><td>   2064</td><td>    648</td><td>    367</td><td>    444</td><td>   3991</td><td>   1808</td><td>   3503</td><td>   1599</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.5444.01A</th><td>  1011 </td><td>     0 </td><td>  1488 </td><td>   627 </td><td>   366 </td><td>   607 </td><td>  5459 </td><td>  1695 </td><td>  1224 </td><td>  1192 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.BA.5556.01A</th><td>   1646</td><td>      1</td><td>   2146</td><td>    763</td><td>    538</td><td>    967</td><td>   9401</td><td>   2521</td><td>   3916</td><td>   2173</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.P3.A6SX.01A</th><td>   1421</td><td>      0</td><td>   2413</td><td>    794</td><td>    986</td><td>     76</td><td>    563</td><td>   2652</td><td>   1788</td><td>   1105</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7242.11A</th><td>   9952</td><td>      9</td><td>   2403</td><td>    832</td><td>    437</td><td>   1000</td><td>   6336</td><td>   1563</td><td>   4157</td><td>   1589</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.DQ.7592.01A</th><td>   2923</td><td>      0</td><td>   2507</td><td>    794</td><td>    650</td><td>    484</td><td>   9116</td><td>   3996</td><td>   4762</td><td>   3113</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6937.01A</th><td>  1232 </td><td>     2 </td><td>  1212 </td><td>   503 </td><td>   210 </td><td>   286 </td><td>   324 </td><td>  1607 </td><td>   866 </td><td>  1250 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.QK.A8ZB.01A</th><td>   2332</td><td>      0</td><td>   3280</td><td>    642</td><td>    507</td><td>    491</td><td>   5042</td><td>   3292</td><td>   2676</td><td>   2995</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7432.01A</th><td>   2032</td><td>      0</td><td>   2069</td><td>    434</td><td>   1081</td><td>    105</td><td>   3398</td><td>   3988</td><td>   4089</td><td>   2119</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7089.01A</th><td>   3005</td><td>      0</td><td>   2056</td><td>    601</td><td>    504</td><td>    392</td><td>   3379</td><td>   3651</td><td>   2524</td><td>   1731</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6939.11A</th><td>   1612</td><td>     53</td><td>    729</td><td>    488</td><td>     45</td><td>    155</td><td>  10545</td><td>   1223</td><td>   1011</td><td>    492</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.BA.4075.01A</th><td>  2950 </td><td>     1 </td><td>  5510 </td><td>   355 </td><td>   710 </td><td>   306 </td><td>  2114 </td><td>  2328 </td><td>  2450 </td><td>  2342 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.T3.A92M.01A</th><td>  1679 </td><td>     0 </td><td>  2430 </td><td>   624 </td><td>   759 </td><td>   379 </td><td>  2443 </td><td>  2379 </td><td>  1900 </td><td>  1833 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>⋮</th><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋱</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7430.01A</th><td>   3632</td><td>      0</td><td>   2857</td><td>    362</td><td>    389</td><td>    136</td><td>    606</td><td>   3344</td><td>  18448</td><td>   1312</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.D6.A74Q.01A</th><td>  2368 </td><td>     0 </td><td>  3792 </td><td>   765 </td><td>   541 </td><td>   307 </td><td>  1291 </td><td>  4462 </td><td>  2878 </td><td>   985 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7255.01A</th><td>   5443</td><td>      0</td><td>   3542</td><td>    884</td><td>    979</td><td>    135</td><td>   5880</td><td>   5834</td><td>   2829</td><td>   4707</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.6223.01A</th><td>   1406</td><td>      1</td><td>   1875</td><td>    623</td><td>    453</td><td>    555</td><td>   3190</td><td>   2858</td><td>   4875</td><td>   1946</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A460.01A</th><td>  1049 </td><td>     0 </td><td>  2070 </td><td>   895 </td><td>   853 </td><td>   985 </td><td>  3735 </td><td>  1697 </td><td>  7706 </td><td>  2500 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7261.01A</th><td>  2048 </td><td>     2 </td><td>  1007 </td><td>   750 </td><td>   487 </td><td>   493 </td><td>  1735 </td><td>  2226 </td><td> 13697 </td><td>  1659 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4736.01A</th><td>   980 </td><td>    35 </td><td>  2072 </td><td>   613 </td><td>   287 </td><td>  2004 </td><td>  6050 </td><td>  3235 </td><td> 15570 </td><td>  1748 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.7404.01A</th><td>  2646 </td><td>    18 </td><td>  2293 </td><td>  1259 </td><td>  1067 </td><td>  1147 </td><td>  6266 </td><td>  3687 </td><td>  8930 </td><td>  3086 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.UF.A719.01A</th><td>  5193 </td><td>     0 </td><td>  1751 </td><td>  1275 </td><td>  1325 </td><td>   203 </td><td>   352 </td><td>  3428 </td><td> 27455 </td><td>  2397 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7236.01A</th><td>  2366 </td><td>     0 </td><td>  1862 </td><td>   392 </td><td>   367 </td><td>   429 </td><td>  5933 </td><td>  2311 </td><td>  4241 </td><td>  3022 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6951.01A</th><td>  3280 </td><td>     1 </td><td>  1973 </td><td>   904 </td><td>   300 </td><td>   111 </td><td>   736 </td><td>  1844 </td><td> 15010 </td><td>  1314 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4728.01A</th><td>   1136</td><td>      1</td><td>   1739</td><td>    668</td><td>    347</td><td>   2618</td><td>   5170</td><td>   2296</td><td>   2764</td><td>   1537</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7090.01A</th><td>   1050</td><td>      3</td><td>   1520</td><td>    464</td><td>    406</td><td>    698</td><td>   2617</td><td>   2863</td><td>   2464</td><td>   1940</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.5979.01A</th><td>   1416</td><td>      0</td><td>   1383</td><td>    594</td><td>    517</td><td>    160</td><td>   6088</td><td>   5182</td><td>   3640</td><td>   1324</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.7069.01A</th><td>   728 </td><td>     0 </td><td>  1603 </td><td>   255 </td><td>   165 </td><td>   200 </td><td>  1027 </td><td>  1372 </td><td>   796 </td><td>  1018 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4733.01A</th><td>    727</td><td>      1</td><td>   1151</td><td>    481</td><td>    463</td><td>    934</td><td>   6624</td><td>   3854</td><td>   2812</td><td>   1833</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.7390.01A</th><td>  1995 </td><td>     1 </td><td>  1561 </td><td>   730 </td><td>   594 </td><td>   382 </td><td>  1708 </td><td>  2618 </td><td> 24128 </td><td>  2214 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45X.01A</th><td>   1795</td><td>      1</td><td>   1913</td><td>    977</td><td>    516</td><td>    211</td><td>   1407</td><td>   1556</td><td>   2578</td><td>   1250</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.IQ.A6SH.01A</th><td>   1428</td><td>      0</td><td>   2404</td><td>    393</td><td>    334</td><td>    166</td><td>   6937</td><td>   3944</td><td>   7729</td><td>   1394</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6962.11A</th><td>  11809</td><td>      4</td><td>   1623</td><td>    981</td><td>    299</td><td>    281</td><td>   9783</td><td>   1691</td><td>   2135</td><td>   1369</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6960.11A</th><td>   3340</td><td>      0</td><td>   1388</td><td>    608</td><td>    206</td><td>    304</td><td>   6363</td><td>   1242</td><td>   2100</td><td>   1369</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A464.01A</th><td>    929</td><td>      2</td><td>   2332</td><td>    472</td><td>    386</td><td>    331</td><td>   7799</td><td>   3028</td><td>   2494</td><td>   1711</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.C9.A47Z.01A</th><td>   1707</td><td>      0</td><td>   1926</td><td>    410</td><td>    210</td><td>    134</td><td>   1264</td><td>   1356</td><td>   3710</td><td>   1671</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.6010.01A</th><td>  2218 </td><td>     0 </td><td>  1574 </td><td>   852 </td><td>   729 </td><td>   550 </td><td>  5558 </td><td>  2921 </td><td>  8749 </td><td>  1596 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.WA.A7GZ.11A</th><td>   2537</td><td>     41</td><td>   1171</td><td>    557</td><td>    127</td><td>    165</td><td>   4651</td><td>    647</td><td>   3029</td><td>    848</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7235.01A</th><td>   492 </td><td>     0 </td><td>   976 </td><td>   376 </td><td>   363 </td><td>   488 </td><td>  5178 </td><td>  2138 </td><td> 20007 </td><td>  4131 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.CX.7086.01A</th><td>   2741</td><td>      0</td><td>   1952</td><td>   1003</td><td>   1103</td><td>    214</td><td>   1809</td><td>   2639</td><td>  13623</td><td>   2530</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6935.11A</th><td>   8492</td><td>      3</td><td>   1578</td><td>    818</td><td>    281</td><td>    419</td><td>   7368</td><td>   1355</td><td>   2276</td><td>   1583</td><td>⋯</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td><td>      0</td></tr>\n",
       "\t<tr><th scope=row>TCGA.P3.A6SW.01A</th><td>   770 </td><td>     1 </td><td>  1569 </td><td>   620 </td><td>   591 </td><td>   462 </td><td>  2082 </td><td>  1603 </td><td> 31675 </td><td>  1473 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "\t<tr><th scope=row>TCGA.HD.A6HZ.01A</th><td>   923 </td><td>     0 </td><td>  1183 </td><td>   607 </td><td>   344 </td><td>   925 </td><td>  2482 </td><td>  1769 </td><td>  3949 </td><td>   899 </td><td>⋯</td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td><td>     0 </td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A matrix: 546 × 60483 of type chr\n",
       "\\begin{tabular}{r|lllllllllllllllllllll}\n",
       "  & ENSG00000000003 & ENSG00000000005 & ENSG00000000419 & ENSG00000000457 & ENSG00000000460 & ENSG00000000938 & ENSG00000000971 & ENSG00000001036 & ENSG00000001084 & ENSG00000001167 & ⋯ & ENSGR0000263980 & ENSGR0000264510 & ENSGR0000264819 & ENSGR0000265658 & ENSGR0000270726 & ENSGR0000275287 & ENSGR0000276543 & ENSGR0000277120 & ENSGR0000280767 & ENSGR0000281849\\\\\n",
       "\\hline\n",
       "\tTCGA.BB.4224.01A &    2237 &       2 &    1606 &    1063 &    1208 &     256 &     177 &    2371 &    2741 &    2515 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.H7.7774.01A &    2740 &       0 &    1691 &     803 &     317 &     330 &    5472 &    2316 &    8370 &     816 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.6943.01A &    2686 &       0 &    1649 &     917 &     402 &    1535 &   15358 &    3490 &    4671 &    2080 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CN.5374.01A &   2086  &      1  &   2333  &   1288  &   1105  &    639  &   5565  &   2065  &   2902  &   1777  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.CQ.6227.01A &   10167 &       9 &    3021 &     537 &     459 &     362 &    6963 &    4883 &    3140 &    2448 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.6959.01A &    1154 &       6 &    2766 &     527 &     747 &     906 &   12856 &    6120 &    7448 &    3527 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.F7.A61V.01A &   1978  &      1  &   1762  &    482  &    331  &    147  &    793  &   2364  &   2827  &   1159  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.CV.7413.01A &    1930 &       1 &    1668 &     671 &     476 &     477 &    3669 &    3366 &    2324 &    1459 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.7247.01A &    1066 &       1 &    1760 &     600 &     874 &     204 &    2791 &    1837 &    9779 &    1916 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CR.5249.01A &    2538 &       0 &    1268 &    1066 &     950 &     924 &    5289 &    2584 &    2971 &    2572 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CQ.5331.01A &    1465 &       0 &    2612 &    1027 &     766 &    1084 &   14982 &    5098 &    7356 &    4672 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.BB.8601.01A &   1630  &      1  &   1227  &    764  &    687  &     42  &    357  &   1270  &  19713  &   1255  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.CV.A45W.01A &    2215 &       0 &    1139 &     526 &     464 &    1024 &    1911 &    1741 &    8343 &    1061 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CQ.7063.01A &     724 &       0 &    1220 &     461 &     235 &     668 &    4934 &    1323 &    1859 &    1229 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CN.5373.01A &     718 &       0 &    1162 &     577 &     232 &     475 &    6444 &    2164 &    2870 &    1650 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.A45T.01A &    2120 &       3 &    2252 &     614 &     340 &     700 &    4178 &    1998 &    1845 &    1197 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.HD.A4C1.01A &   1273  &      2  &   1793  &    646  &    461  &    238  &   4564  &   1802  &   2617  &   1129  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.CV.7438.11A &    4370 &       3 &    2064 &     648 &     367 &     444 &    3991 &    1808 &    3503 &    1599 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.5444.01A &   1011  &      0  &   1488  &    627  &    366  &    607  &   5459  &   1695  &   1224  &   1192  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.BA.5556.01A &    1646 &       1 &    2146 &     763 &     538 &     967 &    9401 &    2521 &    3916 &    2173 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.P3.A6SX.01A &    1421 &       0 &    2413 &     794 &     986 &      76 &     563 &    2652 &    1788 &    1105 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.7242.11A &    9952 &       9 &    2403 &     832 &     437 &    1000 &    6336 &    1563 &    4157 &    1589 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.DQ.7592.01A &    2923 &       0 &    2507 &     794 &     650 &     484 &    9116 &    3996 &    4762 &    3113 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.6937.01A &   1232  &      2  &   1212  &    503  &    210  &    286  &    324  &   1607  &    866  &   1250  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.QK.A8ZB.01A &    2332 &       0 &    3280 &     642 &     507 &     491 &    5042 &    3292 &    2676 &    2995 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.7432.01A &    2032 &       0 &    2069 &     434 &    1081 &     105 &    3398 &    3988 &    4089 &    2119 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.7089.01A &    3005 &       0 &    2056 &     601 &     504 &     392 &    3379 &    3651 &    2524 &    1731 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.6939.11A &    1612 &      53 &     729 &     488 &      45 &     155 &   10545 &    1223 &    1011 &     492 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.BA.4075.01A &   2950  &      1  &   5510  &    355  &    710  &    306  &   2114  &   2328  &   2450  &   2342  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.T3.A92M.01A &   1679  &      0  &   2430  &    624  &    759  &    379  &   2443  &   2379  &   1900  &   1833  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\t⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋱ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n",
       "\tTCGA.CV.7430.01A &    3632 &       0 &    2857 &     362 &     389 &     136 &     606 &    3344 &   18448 &    1312 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.D6.A74Q.01A &   2368  &      0  &   3792  &    765  &    541  &    307  &   1291  &   4462  &   2878  &    985  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.CV.7255.01A &    5443 &       0 &    3542 &     884 &     979 &     135 &    5880 &    5834 &    2829 &    4707 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CQ.6223.01A &    1406 &       1 &    1875 &     623 &     453 &     555 &    3190 &    2858 &    4875 &    1946 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.A460.01A &   1049  &      0  &   2070  &    895  &    853  &    985  &   3735  &   1697  &   7706  &   2500  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.CV.7261.01A &   2048  &      2  &   1007  &    750  &    487  &    493  &   1735  &   2226  &  13697  &   1659  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.CN.4736.01A &    980  &     35  &   2072  &    613  &    287  &   2004  &   6050  &   3235  &  15570  &   1748  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.CR.7404.01A &   2646  &     18  &   2293  &   1259  &   1067  &   1147  &   6266  &   3687  &   8930  &   3086  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.UF.A719.01A &   5193  &      0  &   1751  &   1275  &   1325  &    203  &    352  &   3428  &  27455  &   2397  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.CV.7236.01A &   2366  &      0  &   1862  &    392  &    367  &    429  &   5933  &   2311  &   4241  &   3022  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.CV.6951.01A &   3280  &      1  &   1973  &    904  &    300  &    111  &    736  &   1844  &  15010  &   1314  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.CN.4728.01A &    1136 &       1 &    1739 &     668 &     347 &    2618 &    5170 &    2296 &    2764 &    1537 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.7090.01A &    1050 &       3 &    1520 &     464 &     406 &     698 &    2617 &    2863 &    2464 &    1940 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.5979.01A &    1416 &       0 &    1383 &     594 &     517 &     160 &    6088 &    5182 &    3640 &    1324 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CQ.7069.01A &    728  &      0  &   1603  &    255  &    165  &    200  &   1027  &   1372  &    796  &   1018  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.CN.4733.01A &     727 &       1 &    1151 &     481 &     463 &     934 &    6624 &    3854 &    2812 &    1833 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CR.7390.01A &   1995  &      1  &   1561  &    730  &    594  &    382  &   1708  &   2618  &  24128  &   2214  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.CV.A45X.01A &    1795 &       1 &    1913 &     977 &     516 &     211 &    1407 &    1556 &    2578 &    1250 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.IQ.A6SH.01A &    1428 &       0 &    2404 &     393 &     334 &     166 &    6937 &    3944 &    7729 &    1394 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.6962.11A &   11809 &       4 &    1623 &     981 &     299 &     281 &    9783 &    1691 &    2135 &    1369 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.6960.11A &    3340 &       0 &    1388 &     608 &     206 &     304 &    6363 &    1242 &    2100 &    1369 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.A464.01A &     929 &       2 &    2332 &     472 &     386 &     331 &    7799 &    3028 &    2494 &    1711 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.C9.A47Z.01A &    1707 &       0 &    1926 &     410 &     210 &     134 &    1264 &    1356 &    3710 &    1671 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CN.6010.01A &   2218  &      0  &   1574  &    852  &    729  &    550  &   5558  &   2921  &   8749  &   1596  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.WA.A7GZ.11A &    2537 &      41 &    1171 &     557 &     127 &     165 &    4651 &     647 &    3029 &     848 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.7235.01A &    492  &      0  &    976  &    376  &    363  &    488  &   5178  &   2138  &  20007  &   4131  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.CX.7086.01A &    2741 &       0 &    1952 &    1003 &    1103 &     214 &    1809 &    2639 &   13623 &    2530 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.CV.6935.11A &    8492 &       3 &    1578 &     818 &     281 &     419 &    7368 &    1355 &    2276 &    1583 & ⋯ &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0 &       0\\\\\n",
       "\tTCGA.P3.A6SW.01A &    770  &      1  &   1569  &    620  &    591  &    462  &   2082  &   1603  &  31675  &   1473  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\tTCGA.HD.A6HZ.01A &    923  &      0  &   1183  &    607  &    344  &    925  &   2482  &   1769  &   3949  &    899  & ⋯ &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0  &      0 \\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A matrix: 546 × 60483 of type chr\n",
       "\n",
       "| <!--/--> | ENSG00000000003 | ENSG00000000005 | ENSG00000000419 | ENSG00000000457 | ENSG00000000460 | ENSG00000000938 | ENSG00000000971 | ENSG00000001036 | ENSG00000001084 | ENSG00000001167 | ⋯ | ENSGR0000263980 | ENSGR0000264510 | ENSGR0000264819 | ENSGR0000265658 | ENSGR0000270726 | ENSGR0000275287 | ENSGR0000276543 | ENSGR0000277120 | ENSGR0000280767 | ENSGR0000281849 |\n",
       "|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|\n",
       "| TCGA.BB.4224.01A |    2237 |       2 |    1606 |    1063 |    1208 |     256 |     177 |    2371 |    2741 |    2515 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.H7.7774.01A |    2740 |       0 |    1691 |     803 |     317 |     330 |    5472 |    2316 |    8370 |     816 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.6943.01A |    2686 |       0 |    1649 |     917 |     402 |    1535 |   15358 |    3490 |    4671 |    2080 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CN.5374.01A |   2086  |      1  |   2333  |   1288  |   1105  |    639  |   5565  |   2065  |   2902  |   1777  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.CQ.6227.01A |   10167 |       9 |    3021 |     537 |     459 |     362 |    6963 |    4883 |    3140 |    2448 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.6959.01A |    1154 |       6 |    2766 |     527 |     747 |     906 |   12856 |    6120 |    7448 |    3527 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.F7.A61V.01A |   1978  |      1  |   1762  |    482  |    331  |    147  |    793  |   2364  |   2827  |   1159  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.CV.7413.01A |    1930 |       1 |    1668 |     671 |     476 |     477 |    3669 |    3366 |    2324 |    1459 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.7247.01A |    1066 |       1 |    1760 |     600 |     874 |     204 |    2791 |    1837 |    9779 |    1916 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CR.5249.01A |    2538 |       0 |    1268 |    1066 |     950 |     924 |    5289 |    2584 |    2971 |    2572 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CQ.5331.01A |    1465 |       0 |    2612 |    1027 |     766 |    1084 |   14982 |    5098 |    7356 |    4672 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.BB.8601.01A |   1630  |      1  |   1227  |    764  |    687  |     42  |    357  |   1270  |  19713  |   1255  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.CV.A45W.01A |    2215 |       0 |    1139 |     526 |     464 |    1024 |    1911 |    1741 |    8343 |    1061 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CQ.7063.01A |     724 |       0 |    1220 |     461 |     235 |     668 |    4934 |    1323 |    1859 |    1229 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CN.5373.01A |     718 |       0 |    1162 |     577 |     232 |     475 |    6444 |    2164 |    2870 |    1650 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.A45T.01A |    2120 |       3 |    2252 |     614 |     340 |     700 |    4178 |    1998 |    1845 |    1197 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.HD.A4C1.01A |   1273  |      2  |   1793  |    646  |    461  |    238  |   4564  |   1802  |   2617  |   1129  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.CV.7438.11A |    4370 |       3 |    2064 |     648 |     367 |     444 |    3991 |    1808 |    3503 |    1599 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.5444.01A |   1011  |      0  |   1488  |    627  |    366  |    607  |   5459  |   1695  |   1224  |   1192  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.BA.5556.01A |    1646 |       1 |    2146 |     763 |     538 |     967 |    9401 |    2521 |    3916 |    2173 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.P3.A6SX.01A |    1421 |       0 |    2413 |     794 |     986 |      76 |     563 |    2652 |    1788 |    1105 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.7242.11A |    9952 |       9 |    2403 |     832 |     437 |    1000 |    6336 |    1563 |    4157 |    1589 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.DQ.7592.01A |    2923 |       0 |    2507 |     794 |     650 |     484 |    9116 |    3996 |    4762 |    3113 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.6937.01A |   1232  |      2  |   1212  |    503  |    210  |    286  |    324  |   1607  |    866  |   1250  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.QK.A8ZB.01A |    2332 |       0 |    3280 |     642 |     507 |     491 |    5042 |    3292 |    2676 |    2995 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.7432.01A |    2032 |       0 |    2069 |     434 |    1081 |     105 |    3398 |    3988 |    4089 |    2119 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.7089.01A |    3005 |       0 |    2056 |     601 |     504 |     392 |    3379 |    3651 |    2524 |    1731 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.6939.11A |    1612 |      53 |     729 |     488 |      45 |     155 |   10545 |    1223 |    1011 |     492 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.BA.4075.01A |   2950  |      1  |   5510  |    355  |    710  |    306  |   2114  |   2328  |   2450  |   2342  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.T3.A92M.01A |   1679  |      0  |   2430  |    624  |    759  |    379  |   2443  |   2379  |   1900  |   1833  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋱ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ |\n",
       "| TCGA.CV.7430.01A |    3632 |       0 |    2857 |     362 |     389 |     136 |     606 |    3344 |   18448 |    1312 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.D6.A74Q.01A |   2368  |      0  |   3792  |    765  |    541  |    307  |   1291  |   4462  |   2878  |    985  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.CV.7255.01A |    5443 |       0 |    3542 |     884 |     979 |     135 |    5880 |    5834 |    2829 |    4707 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CQ.6223.01A |    1406 |       1 |    1875 |     623 |     453 |     555 |    3190 |    2858 |    4875 |    1946 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.A460.01A |   1049  |      0  |   2070  |    895  |    853  |    985  |   3735  |   1697  |   7706  |   2500  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.CV.7261.01A |   2048  |      2  |   1007  |    750  |    487  |    493  |   1735  |   2226  |  13697  |   1659  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.CN.4736.01A |    980  |     35  |   2072  |    613  |    287  |   2004  |   6050  |   3235  |  15570  |   1748  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.CR.7404.01A |   2646  |     18  |   2293  |   1259  |   1067  |   1147  |   6266  |   3687  |   8930  |   3086  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.UF.A719.01A |   5193  |      0  |   1751  |   1275  |   1325  |    203  |    352  |   3428  |  27455  |   2397  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.CV.7236.01A |   2366  |      0  |   1862  |    392  |    367  |    429  |   5933  |   2311  |   4241  |   3022  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.CV.6951.01A |   3280  |      1  |   1973  |    904  |    300  |    111  |    736  |   1844  |  15010  |   1314  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.CN.4728.01A |    1136 |       1 |    1739 |     668 |     347 |    2618 |    5170 |    2296 |    2764 |    1537 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.7090.01A |    1050 |       3 |    1520 |     464 |     406 |     698 |    2617 |    2863 |    2464 |    1940 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.5979.01A |    1416 |       0 |    1383 |     594 |     517 |     160 |    6088 |    5182 |    3640 |    1324 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CQ.7069.01A |    728  |      0  |   1603  |    255  |    165  |    200  |   1027  |   1372  |    796  |   1018  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.CN.4733.01A |     727 |       1 |    1151 |     481 |     463 |     934 |    6624 |    3854 |    2812 |    1833 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CR.7390.01A |   1995  |      1  |   1561  |    730  |    594  |    382  |   1708  |   2618  |  24128  |   2214  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.CV.A45X.01A |    1795 |       1 |    1913 |     977 |     516 |     211 |    1407 |    1556 |    2578 |    1250 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.IQ.A6SH.01A |    1428 |       0 |    2404 |     393 |     334 |     166 |    6937 |    3944 |    7729 |    1394 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.6962.11A |   11809 |       4 |    1623 |     981 |     299 |     281 |    9783 |    1691 |    2135 |    1369 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.6960.11A |    3340 |       0 |    1388 |     608 |     206 |     304 |    6363 |    1242 |    2100 |    1369 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.A464.01A |     929 |       2 |    2332 |     472 |     386 |     331 |    7799 |    3028 |    2494 |    1711 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.C9.A47Z.01A |    1707 |       0 |    1926 |     410 |     210 |     134 |    1264 |    1356 |    3710 |    1671 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CN.6010.01A |   2218  |      0  |   1574  |    852  |    729  |    550  |   5558  |   2921  |   8749  |   1596  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.WA.A7GZ.11A |    2537 |      41 |    1171 |     557 |     127 |     165 |    4651 |     647 |    3029 |     848 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.7235.01A |    492  |      0  |    976  |    376  |    363  |    488  |   5178  |   2138  |  20007  |   4131  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.CX.7086.01A |    2741 |       0 |    1952 |    1003 |    1103 |     214 |    1809 |    2639 |   13623 |    2530 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.CV.6935.11A |    8492 |       3 |    1578 |     818 |     281 |     419 |    7368 |    1355 |    2276 |    1583 | ⋯ |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |       0 |\n",
       "| TCGA.P3.A6SW.01A |    770  |      1  |   1569  |    620  |    591  |    462  |   2082  |   1603  |  31675  |   1473  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "| TCGA.HD.A6HZ.01A |    923  |      0  |   1183  |    607  |    344  |    925  |   2482  |   1769  |   3949  |    899  | ⋯ |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |      0  |\n",
       "\n"
      ],
      "text/plain": [
       "                 ENSG00000000003 ENSG00000000005 ENSG00000000419\n",
       "TCGA.BB.4224.01A    2237               2            1606        \n",
       "TCGA.H7.7774.01A    2740               0            1691        \n",
       "TCGA.CV.6943.01A    2686               0            1649        \n",
       "TCGA.CN.5374.01A   2086               1            2333         \n",
       "TCGA.CQ.6227.01A   10167               9            3021        \n",
       "TCGA.CV.6959.01A    1154               6            2766        \n",
       "TCGA.F7.A61V.01A   1978               1            1762         \n",
       "TCGA.CV.7413.01A    1930               1            1668        \n",
       "TCGA.CV.7247.01A    1066               1            1760        \n",
       "TCGA.CR.5249.01A    2538               0            1268        \n",
       "TCGA.CQ.5331.01A    1465               0            2612        \n",
       "TCGA.BB.8601.01A   1630               1            1227         \n",
       "TCGA.CV.A45W.01A    2215               0            1139        \n",
       "TCGA.CQ.7063.01A     724               0            1220        \n",
       "TCGA.CN.5373.01A     718               0            1162        \n",
       "TCGA.CV.A45T.01A    2120               3            2252        \n",
       "TCGA.HD.A4C1.01A   1273               2            1793         \n",
       "TCGA.CV.7438.11A    4370               3            2064        \n",
       "TCGA.CV.5444.01A   1011               0            1488         \n",
       "TCGA.BA.5556.01A    1646               1            2146        \n",
       "TCGA.P3.A6SX.01A    1421               0            2413        \n",
       "TCGA.CV.7242.11A    9952               9            2403        \n",
       "TCGA.DQ.7592.01A    2923               0            2507        \n",
       "TCGA.CV.6937.01A   1232               2            1212         \n",
       "TCGA.QK.A8ZB.01A    2332               0            3280        \n",
       "TCGA.CV.7432.01A    2032               0            2069        \n",
       "TCGA.CV.7089.01A    3005               0            2056        \n",
       "TCGA.CV.6939.11A    1612              53             729        \n",
       "TCGA.BA.4075.01A   2950               1            5510         \n",
       "TCGA.T3.A92M.01A   1679               0            2430         \n",
       "⋮                ⋮               ⋮               ⋮              \n",
       "TCGA.CV.7430.01A    3632               0            2857        \n",
       "TCGA.D6.A74Q.01A   2368               0            3792         \n",
       "TCGA.CV.7255.01A    5443               0            3542        \n",
       "TCGA.CQ.6223.01A    1406               1            1875        \n",
       "TCGA.CV.A460.01A   1049               0            2070         \n",
       "TCGA.CV.7261.01A   2048               2            1007         \n",
       "TCGA.CN.4736.01A    980              35            2072         \n",
       "TCGA.CR.7404.01A   2646              18            2293         \n",
       "TCGA.UF.A719.01A   5193               0            1751         \n",
       "TCGA.CV.7236.01A   2366               0            1862         \n",
       "TCGA.CV.6951.01A   3280               1            1973         \n",
       "TCGA.CN.4728.01A    1136               1            1739        \n",
       "TCGA.CV.7090.01A    1050               3            1520        \n",
       "TCGA.CV.5979.01A    1416               0            1383        \n",
       "TCGA.CQ.7069.01A    728               0            1603         \n",
       "TCGA.CN.4733.01A     727               1            1151        \n",
       "TCGA.CR.7390.01A   1995               1            1561         \n",
       "TCGA.CV.A45X.01A    1795               1            1913        \n",
       "TCGA.IQ.A6SH.01A    1428               0            2404        \n",
       "TCGA.CV.6962.11A   11809               4            1623        \n",
       "TCGA.CV.6960.11A    3340               0            1388        \n",
       "TCGA.CV.A464.01A     929               2            2332        \n",
       "TCGA.C9.A47Z.01A    1707               0            1926        \n",
       "TCGA.CN.6010.01A   2218               0            1574         \n",
       "TCGA.WA.A7GZ.11A    2537              41            1171        \n",
       "TCGA.CV.7235.01A    492               0             976         \n",
       "TCGA.CX.7086.01A    2741               0            1952        \n",
       "TCGA.CV.6935.11A    8492               3            1578        \n",
       "TCGA.P3.A6SW.01A    770               1            1569         \n",
       "TCGA.HD.A6HZ.01A    923               0            1183         \n",
       "                 ENSG00000000457 ENSG00000000460 ENSG00000000938\n",
       "TCGA.BB.4224.01A    1063            1208             256        \n",
       "TCGA.H7.7774.01A     803             317             330        \n",
       "TCGA.CV.6943.01A     917             402            1535        \n",
       "TCGA.CN.5374.01A   1288            1105             639         \n",
       "TCGA.CQ.6227.01A     537             459             362        \n",
       "TCGA.CV.6959.01A     527             747             906        \n",
       "TCGA.F7.A61V.01A    482             331             147         \n",
       "TCGA.CV.7413.01A     671             476             477        \n",
       "TCGA.CV.7247.01A     600             874             204        \n",
       "TCGA.CR.5249.01A    1066             950             924        \n",
       "TCGA.CQ.5331.01A    1027             766            1084        \n",
       "TCGA.BB.8601.01A    764             687              42         \n",
       "TCGA.CV.A45W.01A     526             464            1024        \n",
       "TCGA.CQ.7063.01A     461             235             668        \n",
       "TCGA.CN.5373.01A     577             232             475        \n",
       "TCGA.CV.A45T.01A     614             340             700        \n",
       "TCGA.HD.A4C1.01A    646             461             238         \n",
       "TCGA.CV.7438.11A     648             367             444        \n",
       "TCGA.CV.5444.01A    627             366             607         \n",
       "TCGA.BA.5556.01A     763             538             967        \n",
       "TCGA.P3.A6SX.01A     794             986              76        \n",
       "TCGA.CV.7242.11A     832             437            1000        \n",
       "TCGA.DQ.7592.01A     794             650             484        \n",
       "TCGA.CV.6937.01A    503             210             286         \n",
       "TCGA.QK.A8ZB.01A     642             507             491        \n",
       "TCGA.CV.7432.01A     434            1081             105        \n",
       "TCGA.CV.7089.01A     601             504             392        \n",
       "TCGA.CV.6939.11A     488              45             155        \n",
       "TCGA.BA.4075.01A    355             710             306         \n",
       "TCGA.T3.A92M.01A    624             759             379         \n",
       "⋮                ⋮               ⋮               ⋮              \n",
       "TCGA.CV.7430.01A     362             389             136        \n",
       "TCGA.D6.A74Q.01A    765             541             307         \n",
       "TCGA.CV.7255.01A     884             979             135        \n",
       "TCGA.CQ.6223.01A     623             453             555        \n",
       "TCGA.CV.A460.01A    895             853             985         \n",
       "TCGA.CV.7261.01A    750             487             493         \n",
       "TCGA.CN.4736.01A    613             287            2004         \n",
       "TCGA.CR.7404.01A   1259            1067            1147         \n",
       "TCGA.UF.A719.01A   1275            1325             203         \n",
       "TCGA.CV.7236.01A    392             367             429         \n",
       "TCGA.CV.6951.01A    904             300             111         \n",
       "TCGA.CN.4728.01A     668             347            2618        \n",
       "TCGA.CV.7090.01A     464             406             698        \n",
       "TCGA.CV.5979.01A     594             517             160        \n",
       "TCGA.CQ.7069.01A    255             165             200         \n",
       "TCGA.CN.4733.01A     481             463             934        \n",
       "TCGA.CR.7390.01A    730             594             382         \n",
       "TCGA.CV.A45X.01A     977             516             211        \n",
       "TCGA.IQ.A6SH.01A     393             334             166        \n",
       "TCGA.CV.6962.11A     981             299             281        \n",
       "TCGA.CV.6960.11A     608             206             304        \n",
       "TCGA.CV.A464.01A     472             386             331        \n",
       "TCGA.C9.A47Z.01A     410             210             134        \n",
       "TCGA.CN.6010.01A    852             729             550         \n",
       "TCGA.WA.A7GZ.11A     557             127             165        \n",
       "TCGA.CV.7235.01A    376             363             488         \n",
       "TCGA.CX.7086.01A    1003            1103             214        \n",
       "TCGA.CV.6935.11A     818             281             419        \n",
       "TCGA.P3.A6SW.01A    620             591             462         \n",
       "TCGA.HD.A6HZ.01A    607             344             925         \n",
       "                 ENSG00000000971 ENSG00000001036 ENSG00000001084\n",
       "TCGA.BB.4224.01A     177            2371            2741        \n",
       "TCGA.H7.7774.01A    5472            2316            8370        \n",
       "TCGA.CV.6943.01A   15358            3490            4671        \n",
       "TCGA.CN.5374.01A   5565            2065            2902         \n",
       "TCGA.CQ.6227.01A    6963            4883            3140        \n",
       "TCGA.CV.6959.01A   12856            6120            7448        \n",
       "TCGA.F7.A61V.01A    793            2364            2827         \n",
       "TCGA.CV.7413.01A    3669            3366            2324        \n",
       "TCGA.CV.7247.01A    2791            1837            9779        \n",
       "TCGA.CR.5249.01A    5289            2584            2971        \n",
       "TCGA.CQ.5331.01A   14982            5098            7356        \n",
       "TCGA.BB.8601.01A    357            1270           19713         \n",
       "TCGA.CV.A45W.01A    1911            1741            8343        \n",
       "TCGA.CQ.7063.01A    4934            1323            1859        \n",
       "TCGA.CN.5373.01A    6444            2164            2870        \n",
       "TCGA.CV.A45T.01A    4178            1998            1845        \n",
       "TCGA.HD.A4C1.01A   4564            1802            2617         \n",
       "TCGA.CV.7438.11A    3991            1808            3503        \n",
       "TCGA.CV.5444.01A   5459            1695            1224         \n",
       "TCGA.BA.5556.01A    9401            2521            3916        \n",
       "TCGA.P3.A6SX.01A     563            2652            1788        \n",
       "TCGA.CV.7242.11A    6336            1563            4157        \n",
       "TCGA.DQ.7592.01A    9116            3996            4762        \n",
       "TCGA.CV.6937.01A    324            1607             866         \n",
       "TCGA.QK.A8ZB.01A    5042            3292            2676        \n",
       "TCGA.CV.7432.01A    3398            3988            4089        \n",
       "TCGA.CV.7089.01A    3379            3651            2524        \n",
       "TCGA.CV.6939.11A   10545            1223            1011        \n",
       "TCGA.BA.4075.01A   2114            2328            2450         \n",
       "TCGA.T3.A92M.01A   2443            2379            1900         \n",
       "⋮                ⋮               ⋮               ⋮              \n",
       "TCGA.CV.7430.01A     606            3344           18448        \n",
       "TCGA.D6.A74Q.01A   1291            4462            2878         \n",
       "TCGA.CV.7255.01A    5880            5834            2829        \n",
       "TCGA.CQ.6223.01A    3190            2858            4875        \n",
       "TCGA.CV.A460.01A   3735            1697            7706         \n",
       "TCGA.CV.7261.01A   1735            2226           13697         \n",
       "TCGA.CN.4736.01A   6050            3235           15570         \n",
       "TCGA.CR.7404.01A   6266            3687            8930         \n",
       "TCGA.UF.A719.01A    352            3428           27455         \n",
       "TCGA.CV.7236.01A   5933            2311            4241         \n",
       "TCGA.CV.6951.01A    736            1844           15010         \n",
       "TCGA.CN.4728.01A    5170            2296            2764        \n",
       "TCGA.CV.7090.01A    2617            2863            2464        \n",
       "TCGA.CV.5979.01A    6088            5182            3640        \n",
       "TCGA.CQ.7069.01A   1027            1372             796         \n",
       "TCGA.CN.4733.01A    6624            3854            2812        \n",
       "TCGA.CR.7390.01A   1708            2618           24128         \n",
       "TCGA.CV.A45X.01A    1407            1556            2578        \n",
       "TCGA.IQ.A6SH.01A    6937            3944            7729        \n",
       "TCGA.CV.6962.11A    9783            1691            2135        \n",
       "TCGA.CV.6960.11A    6363            1242            2100        \n",
       "TCGA.CV.A464.01A    7799            3028            2494        \n",
       "TCGA.C9.A47Z.01A    1264            1356            3710        \n",
       "TCGA.CN.6010.01A   5558            2921            8749         \n",
       "TCGA.WA.A7GZ.11A    4651             647            3029        \n",
       "TCGA.CV.7235.01A   5178            2138           20007         \n",
       "TCGA.CX.7086.01A    1809            2639           13623        \n",
       "TCGA.CV.6935.11A    7368            1355            2276        \n",
       "TCGA.P3.A6SW.01A   2082            1603           31675         \n",
       "TCGA.HD.A6HZ.01A   2482            1769            3949         \n",
       "                 ENSG00000001167 ⋯ ENSGR0000263980 ENSGR0000264510\n",
       "TCGA.BB.4224.01A    2515         ⋯       0               0        \n",
       "TCGA.H7.7774.01A     816         ⋯       0               0        \n",
       "TCGA.CV.6943.01A    2080         ⋯       0               0        \n",
       "TCGA.CN.5374.01A   1777          ⋯      0               0         \n",
       "TCGA.CQ.6227.01A    2448         ⋯       0               0        \n",
       "TCGA.CV.6959.01A    3527         ⋯       0               0        \n",
       "TCGA.F7.A61V.01A   1159          ⋯      0               0         \n",
       "TCGA.CV.7413.01A    1459         ⋯       0               0        \n",
       "TCGA.CV.7247.01A    1916         ⋯       0               0        \n",
       "TCGA.CR.5249.01A    2572         ⋯       0               0        \n",
       "TCGA.CQ.5331.01A    4672         ⋯       0               0        \n",
       "TCGA.BB.8601.01A   1255          ⋯      0               0         \n",
       "TCGA.CV.A45W.01A    1061         ⋯       0               0        \n",
       "TCGA.CQ.7063.01A    1229         ⋯       0               0        \n",
       "TCGA.CN.5373.01A    1650         ⋯       0               0        \n",
       "TCGA.CV.A45T.01A    1197         ⋯       0               0        \n",
       "TCGA.HD.A4C1.01A   1129          ⋯      0               0         \n",
       "TCGA.CV.7438.11A    1599         ⋯       0               0        \n",
       "TCGA.CV.5444.01A   1192          ⋯      0               0         \n",
       "TCGA.BA.5556.01A    2173         ⋯       0               0        \n",
       "TCGA.P3.A6SX.01A    1105         ⋯       0               0        \n",
       "TCGA.CV.7242.11A    1589         ⋯       0               0        \n",
       "TCGA.DQ.7592.01A    3113         ⋯       0               0        \n",
       "TCGA.CV.6937.01A   1250          ⋯      0               0         \n",
       "TCGA.QK.A8ZB.01A    2995         ⋯       0               0        \n",
       "TCGA.CV.7432.01A    2119         ⋯       0               0        \n",
       "TCGA.CV.7089.01A    1731         ⋯       0               0        \n",
       "TCGA.CV.6939.11A     492         ⋯       0               0        \n",
       "TCGA.BA.4075.01A   2342          ⋯      0               0         \n",
       "TCGA.T3.A92M.01A   1833          ⋯      0               0         \n",
       "⋮                ⋮               ⋱ ⋮               ⋮              \n",
       "TCGA.CV.7430.01A    1312         ⋯       0               0        \n",
       "TCGA.D6.A74Q.01A    985          ⋯      0               0         \n",
       "TCGA.CV.7255.01A    4707         ⋯       0               0        \n",
       "TCGA.CQ.6223.01A    1946         ⋯       0               0        \n",
       "TCGA.CV.A460.01A   2500          ⋯      0               0         \n",
       "TCGA.CV.7261.01A   1659          ⋯      0               0         \n",
       "TCGA.CN.4736.01A   1748          ⋯      0               0         \n",
       "TCGA.CR.7404.01A   3086          ⋯      0               0         \n",
       "TCGA.UF.A719.01A   2397          ⋯      0               0         \n",
       "TCGA.CV.7236.01A   3022          ⋯      0               0         \n",
       "TCGA.CV.6951.01A   1314          ⋯      0               0         \n",
       "TCGA.CN.4728.01A    1537         ⋯       0               0        \n",
       "TCGA.CV.7090.01A    1940         ⋯       0               0        \n",
       "TCGA.CV.5979.01A    1324         ⋯       0               0        \n",
       "TCGA.CQ.7069.01A   1018          ⋯      0               0         \n",
       "TCGA.CN.4733.01A    1833         ⋯       0               0        \n",
       "TCGA.CR.7390.01A   2214          ⋯      0               0         \n",
       "TCGA.CV.A45X.01A    1250         ⋯       0               0        \n",
       "TCGA.IQ.A6SH.01A    1394         ⋯       0               0        \n",
       "TCGA.CV.6962.11A    1369         ⋯       0               0        \n",
       "TCGA.CV.6960.11A    1369         ⋯       0               0        \n",
       "TCGA.CV.A464.01A    1711         ⋯       0               0        \n",
       "TCGA.C9.A47Z.01A    1671         ⋯       0               0        \n",
       "TCGA.CN.6010.01A   1596          ⋯      0               0         \n",
       "TCGA.WA.A7GZ.11A     848         ⋯       0               0        \n",
       "TCGA.CV.7235.01A   4131          ⋯      0               0         \n",
       "TCGA.CX.7086.01A    2530         ⋯       0               0        \n",
       "TCGA.CV.6935.11A    1583         ⋯       0               0        \n",
       "TCGA.P3.A6SW.01A   1473          ⋯      0               0         \n",
       "TCGA.HD.A6HZ.01A    899          ⋯      0               0         \n",
       "                 ENSGR0000264819 ENSGR0000265658 ENSGR0000270726\n",
       "TCGA.BB.4224.01A       0               0               0        \n",
       "TCGA.H7.7774.01A       0               0               0        \n",
       "TCGA.CV.6943.01A       0               0               0        \n",
       "TCGA.CN.5374.01A      0               0               0         \n",
       "TCGA.CQ.6227.01A       0               0               0        \n",
       "TCGA.CV.6959.01A       0               0               0        \n",
       "TCGA.F7.A61V.01A      0               0               0         \n",
       "TCGA.CV.7413.01A       0               0               0        \n",
       "TCGA.CV.7247.01A       0               0               0        \n",
       "TCGA.CR.5249.01A       0               0               0        \n",
       "TCGA.CQ.5331.01A       0               0               0        \n",
       "TCGA.BB.8601.01A      0               0               0         \n",
       "TCGA.CV.A45W.01A       0               0               0        \n",
       "TCGA.CQ.7063.01A       0               0               0        \n",
       "TCGA.CN.5373.01A       0               0               0        \n",
       "TCGA.CV.A45T.01A       0               0               0        \n",
       "TCGA.HD.A4C1.01A      0               0               0         \n",
       "TCGA.CV.7438.11A       0               0               0        \n",
       "TCGA.CV.5444.01A      0               0               0         \n",
       "TCGA.BA.5556.01A       0               0               0        \n",
       "TCGA.P3.A6SX.01A       0               0               0        \n",
       "TCGA.CV.7242.11A       0               0               0        \n",
       "TCGA.DQ.7592.01A       0               0               0        \n",
       "TCGA.CV.6937.01A      0               0               0         \n",
       "TCGA.QK.A8ZB.01A       0               0               0        \n",
       "TCGA.CV.7432.01A       0               0               0        \n",
       "TCGA.CV.7089.01A       0               0               0        \n",
       "TCGA.CV.6939.11A       0               0               0        \n",
       "TCGA.BA.4075.01A      0               0               0         \n",
       "TCGA.T3.A92M.01A      0               0               0         \n",
       "⋮                ⋮               ⋮               ⋮              \n",
       "TCGA.CV.7430.01A       0               0               0        \n",
       "TCGA.D6.A74Q.01A      0               0               0         \n",
       "TCGA.CV.7255.01A       0               0               0        \n",
       "TCGA.CQ.6223.01A       0               0               0        \n",
       "TCGA.CV.A460.01A      0               0               0         \n",
       "TCGA.CV.7261.01A      0               0               0         \n",
       "TCGA.CN.4736.01A      0               0               0         \n",
       "TCGA.CR.7404.01A      0               0               0         \n",
       "TCGA.UF.A719.01A      0               0               0         \n",
       "TCGA.CV.7236.01A      0               0               0         \n",
       "TCGA.CV.6951.01A      0               0               0         \n",
       "TCGA.CN.4728.01A       0               0               0        \n",
       "TCGA.CV.7090.01A       0               0               0        \n",
       "TCGA.CV.5979.01A       0               0               0        \n",
       "TCGA.CQ.7069.01A      0               0               0         \n",
       "TCGA.CN.4733.01A       0               0               0        \n",
       "TCGA.CR.7390.01A      0               0               0         \n",
       "TCGA.CV.A45X.01A       0               0               0        \n",
       "TCGA.IQ.A6SH.01A       0               0               0        \n",
       "TCGA.CV.6962.11A       0               0               0        \n",
       "TCGA.CV.6960.11A       0               0               0        \n",
       "TCGA.CV.A464.01A       0               0               0        \n",
       "TCGA.C9.A47Z.01A       0               0               0        \n",
       "TCGA.CN.6010.01A      0               0               0         \n",
       "TCGA.WA.A7GZ.11A       0               0               0        \n",
       "TCGA.CV.7235.01A      0               0               0         \n",
       "TCGA.CX.7086.01A       0               0               0        \n",
       "TCGA.CV.6935.11A       0               0               0        \n",
       "TCGA.P3.A6SW.01A      0               0               0         \n",
       "TCGA.HD.A6HZ.01A      0               0               0         \n",
       "                 ENSGR0000275287 ENSGR0000276543 ENSGR0000277120\n",
       "TCGA.BB.4224.01A       0               0               0        \n",
       "TCGA.H7.7774.01A       0               0               0        \n",
       "TCGA.CV.6943.01A       0               0               0        \n",
       "TCGA.CN.5374.01A      0               0               0         \n",
       "TCGA.CQ.6227.01A       0               0               0        \n",
       "TCGA.CV.6959.01A       0               0               0        \n",
       "TCGA.F7.A61V.01A      0               0               0         \n",
       "TCGA.CV.7413.01A       0               0               0        \n",
       "TCGA.CV.7247.01A       0               0               0        \n",
       "TCGA.CR.5249.01A       0               0               0        \n",
       "TCGA.CQ.5331.01A       0               0               0        \n",
       "TCGA.BB.8601.01A      0               0               0         \n",
       "TCGA.CV.A45W.01A       0               0               0        \n",
       "TCGA.CQ.7063.01A       0               0               0        \n",
       "TCGA.CN.5373.01A       0               0               0        \n",
       "TCGA.CV.A45T.01A       0               0               0        \n",
       "TCGA.HD.A4C1.01A      0               0               0         \n",
       "TCGA.CV.7438.11A       0               0               0        \n",
       "TCGA.CV.5444.01A      0               0               0         \n",
       "TCGA.BA.5556.01A       0               0               0        \n",
       "TCGA.P3.A6SX.01A       0               0               0        \n",
       "TCGA.CV.7242.11A       0               0               0        \n",
       "TCGA.DQ.7592.01A       0               0               0        \n",
       "TCGA.CV.6937.01A      0               0               0         \n",
       "TCGA.QK.A8ZB.01A       0               0               0        \n",
       "TCGA.CV.7432.01A       0               0               0        \n",
       "TCGA.CV.7089.01A       0               0               0        \n",
       "TCGA.CV.6939.11A       0               0               0        \n",
       "TCGA.BA.4075.01A      0               0               0         \n",
       "TCGA.T3.A92M.01A      0               0               0         \n",
       "⋮                ⋮               ⋮               ⋮              \n",
       "TCGA.CV.7430.01A       0               0               0        \n",
       "TCGA.D6.A74Q.01A      0               0               0         \n",
       "TCGA.CV.7255.01A       0               0               0        \n",
       "TCGA.CQ.6223.01A       0               0               0        \n",
       "TCGA.CV.A460.01A      0               0               0         \n",
       "TCGA.CV.7261.01A      0               0               0         \n",
       "TCGA.CN.4736.01A      0               0               0         \n",
       "TCGA.CR.7404.01A      0               0               0         \n",
       "TCGA.UF.A719.01A      0               0               0         \n",
       "TCGA.CV.7236.01A      0               0               0         \n",
       "TCGA.CV.6951.01A      0               0               0         \n",
       "TCGA.CN.4728.01A       0               0               0        \n",
       "TCGA.CV.7090.01A       0               0               0        \n",
       "TCGA.CV.5979.01A       0               0               0        \n",
       "TCGA.CQ.7069.01A      0               0               0         \n",
       "TCGA.CN.4733.01A       0               0               0        \n",
       "TCGA.CR.7390.01A      0               0               0         \n",
       "TCGA.CV.A45X.01A       0               0               0        \n",
       "TCGA.IQ.A6SH.01A       0               0               0        \n",
       "TCGA.CV.6962.11A       0               0               0        \n",
       "TCGA.CV.6960.11A       0               0               0        \n",
       "TCGA.CV.A464.01A       0               0               0        \n",
       "TCGA.C9.A47Z.01A       0               0               0        \n",
       "TCGA.CN.6010.01A      0               0               0         \n",
       "TCGA.WA.A7GZ.11A       0               0               0        \n",
       "TCGA.CV.7235.01A      0               0               0         \n",
       "TCGA.CX.7086.01A       0               0               0        \n",
       "TCGA.CV.6935.11A       0               0               0        \n",
       "TCGA.P3.A6SW.01A      0               0               0         \n",
       "TCGA.HD.A6HZ.01A      0               0               0         \n",
       "                 ENSGR0000280767 ENSGR0000281849\n",
       "TCGA.BB.4224.01A       0               0        \n",
       "TCGA.H7.7774.01A       0               0        \n",
       "TCGA.CV.6943.01A       0               0        \n",
       "TCGA.CN.5374.01A      0               0         \n",
       "TCGA.CQ.6227.01A       0               0        \n",
       "TCGA.CV.6959.01A       0               0        \n",
       "TCGA.F7.A61V.01A      0               0         \n",
       "TCGA.CV.7413.01A       0               0        \n",
       "TCGA.CV.7247.01A       0               0        \n",
       "TCGA.CR.5249.01A       0               0        \n",
       "TCGA.CQ.5331.01A       0               0        \n",
       "TCGA.BB.8601.01A      0               0         \n",
       "TCGA.CV.A45W.01A       0               0        \n",
       "TCGA.CQ.7063.01A       0               0        \n",
       "TCGA.CN.5373.01A       0               0        \n",
       "TCGA.CV.A45T.01A       0               0        \n",
       "TCGA.HD.A4C1.01A      0               0         \n",
       "TCGA.CV.7438.11A       0               0        \n",
       "TCGA.CV.5444.01A      0               0         \n",
       "TCGA.BA.5556.01A       0               0        \n",
       "TCGA.P3.A6SX.01A       0               0        \n",
       "TCGA.CV.7242.11A       0               0        \n",
       "TCGA.DQ.7592.01A       0               0        \n",
       "TCGA.CV.6937.01A      0               0         \n",
       "TCGA.QK.A8ZB.01A       0               0        \n",
       "TCGA.CV.7432.01A       0               0        \n",
       "TCGA.CV.7089.01A       0               0        \n",
       "TCGA.CV.6939.11A       0               0        \n",
       "TCGA.BA.4075.01A      0               0         \n",
       "TCGA.T3.A92M.01A      0               0         \n",
       "⋮                ⋮               ⋮              \n",
       "TCGA.CV.7430.01A       0               0        \n",
       "TCGA.D6.A74Q.01A      0               0         \n",
       "TCGA.CV.7255.01A       0               0        \n",
       "TCGA.CQ.6223.01A       0               0        \n",
       "TCGA.CV.A460.01A      0               0         \n",
       "TCGA.CV.7261.01A      0               0         \n",
       "TCGA.CN.4736.01A      0               0         \n",
       "TCGA.CR.7404.01A      0               0         \n",
       "TCGA.UF.A719.01A      0               0         \n",
       "TCGA.CV.7236.01A      0               0         \n",
       "TCGA.CV.6951.01A      0               0         \n",
       "TCGA.CN.4728.01A       0               0        \n",
       "TCGA.CV.7090.01A       0               0        \n",
       "TCGA.CV.5979.01A       0               0        \n",
       "TCGA.CQ.7069.01A      0               0         \n",
       "TCGA.CN.4733.01A       0               0        \n",
       "TCGA.CR.7390.01A      0               0         \n",
       "TCGA.CV.A45X.01A       0               0        \n",
       "TCGA.IQ.A6SH.01A       0               0        \n",
       "TCGA.CV.6962.11A       0               0        \n",
       "TCGA.CV.6960.11A       0               0        \n",
       "TCGA.CV.A464.01A       0               0        \n",
       "TCGA.C9.A47Z.01A       0               0        \n",
       "TCGA.CN.6010.01A      0               0         \n",
       "TCGA.WA.A7GZ.11A       0               0        \n",
       "TCGA.CV.7235.01A      0               0         \n",
       "TCGA.CX.7086.01A       0               0        \n",
       "TCGA.CV.6935.11A       0               0        \n",
       "TCGA.P3.A6SW.01A      0               0         \n",
       "TCGA.HD.A6HZ.01A      0               0         "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "df_TCGA_t"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 9,
   "id": "7c591381",
   "metadata": {
    "scrolled": true
   },
   "outputs": [],
   "source": [
    "df_Puram_t <- t(df_Puram)\n",
    "colnames(df_Puram_t)<-df_Puram_t[1,]\n",
    "df_Puram_t <- df_Puram_t[-1,]"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 10,
   "id": "72586a16",
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A matrix: 5902 × 21813 of type chr</caption>\n",
       "<thead>\n",
       "\t<tr><th></th><th scope=col>ENSG00000121410</th><th scope=col>ENSG00000268895</th><th scope=col>ENSG00000148584</th><th scope=col>ENSG00000175899</th><th scope=col>ENSG00000245105</th><th scope=col>ENSG00000166535</th><th scope=col>ENSG00000256069</th><th scope=col>ENSG00000128274</th><th scope=col>ENSG00000118017</th><th scope=col>ENSG00000265544</th><th scope=col>⋯</th><th scope=col>ENSG00000174442</th><th scope=col>ENSG00000122952</th><th scope=col>ENSG00000198205</th><th scope=col>ENSG00000198455</th><th scope=col>ENSG00000070476</th><th scope=col>ENSG00000203995</th><th scope=col>ENSG00000162378</th><th scope=col>ENSG00000159840</th><th scope=col>ENSG00000074755</th><th scope=col>ENSG00000036549</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><th scope=row>HN28_P15_D06_S330_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 9.6830000</td><td> 0.1763200</td><td> 0.0000000</td><td> 0.0000000</td><td> 2.2488000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.1216800</td><td> 0.1635000</td><td> 0.0908530</td><td> 4.2748000</td><td> 0.0000000</td><td> 0.0000000</td></tr>\n",
       "\t<tr><th scope=row>HN28_P6_G05_S173_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 7.5830000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.1953500</td><td> 0.2797700</td><td> 3.9348000</td><td> 0.0000000</td><td> 3.7716000</td><td> 0.0000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P14_D11_S239_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0299830</td><td> 0.0000000</td><td> 4.7988000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0214800</td><td> 0.0000000</td><td> 0.0731350</td><td> 0.0000000</td><td> 1.3045000</td><td> 2.1120000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P14_H05_S281_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 6.0547000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.2642400</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0894980</td><td> 0.1865000</td><td> 0.2141200</td><td> 0.1243300</td><td> 0.0935600</td><td> 0.0000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P25_H09_S189_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 2.1385000</td><td> 0.2289700</td><td> 0.1335600</td><td> 2.9059000</td><td> 3.0034000</td><td> 0.0000000</td><td> 0.0000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P14_H06_S282_comb</th><td> 0.0662610</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 2.2830000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.8718400</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 1.2016000</td><td> 0.0635030</td><td> 0.0510240</td><td> 0.6050200</td><td> 0.0000000</td><td> 0.0000000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_C04_S316_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.1966100</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.3628900</td><td> 1.0881000</td><td> 0.8559900</td><td> 0.0000000</td><td> 0.8567900</td><td> 0.0000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P25_A11_S107_comb</th><td> 0.5410200</td><td> 0.0000000</td><td> 0.0000000</td><td> 7.7060000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 4.6348000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0976110</td><td> 0.0676390</td><td> 0.0000000</td><td> 5.2928000</td><td> 0.0000000</td><td> 0.0000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P25_C09_S129_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 1.1250000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0621220</td><td> 0.0328060</td><td> 0.0922070</td><td> 0.0000000</td><td> 0.0172090</td><td> 0.0000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_H05_S377_comb</th><td> 1.3004000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 2.6192000</td><td> 0.1256500</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.6229300</td><td> 0.2215700</td><td> 0.4200800</td><td> 0.5568000</td><td> 0.0000000</td><td> 0.0000000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_E10_S58_comb</th><td> 1.983300 </td><td> 0.000000 </td><td> 0.000000 </td><td> 7.285600 </td><td> 0.000000 </td><td> 0.000000 </td><td> 0.000000 </td><td> 4.445100 </td><td> 0.000000 </td><td> 0.000000 </td><td>⋯</td><td> 0.000000 </td><td> 0.000000 </td><td> 0.000000 </td><td> 0.000000 </td><td> 0.028569 </td><td> 0.332280 </td><td> 0.313830 </td><td> 3.916600 </td><td> 0.000000 </td><td> 0.000000 </td></tr>\n",
       "\t<tr><th scope=row>HN25_P24_B02_S110_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 1.9505000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 3.7281000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 1.0468000</td><td> 1.9381000</td><td> 0.2363400</td><td> 0.4467900</td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_C01_S313_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.1003000</td><td> 0.5916800</td><td> 0.1890300</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td></tr>\n",
       "\t<tr><th scope=row>HN28_P15_G06_S366_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 7.8525000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 4.3319000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.3584000</td><td> 4.3710000</td><td> 0.0000000</td><td> 0.0000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P6_B06_S18_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 8.3136000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 7.0375000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.1230000</td><td> 0.2215700</td><td> 0.2545900</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_C05_S29_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0496310</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 2.1496000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.7311800</td><td> 0.0000000</td><td> 0.0662610</td><td> 0.0000000</td><td> 0.6397000</td><td> 3.1760000</td><td> 0.0000000</td><td> 0.0000000</td></tr>\n",
       "\t<tr><th scope=row>HN28_P6_D09_S141_comb</th><td> 0.000000 </td><td> 0.000000 </td><td> 0.000000 </td><td> 0.000000 </td><td> 0.000000 </td><td> 0.000000 </td><td> 0.000000 </td><td> 0.000000 </td><td> 0.000000 </td><td> 0.000000 </td><td>⋯</td><td> 0.000000 </td><td> 0.000000 </td><td> 0.000000 </td><td> 0.000000 </td><td> 0.000000 </td><td> 0.000000 </td><td> 0.458380 </td><td> 2.233300 </td><td> 0.000000 </td><td> 0.000000 </td></tr>\n",
       "\t<tr><th scope=row>HN26_P5_H01_S85_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 4.8070000</td><td> 0.0000000</td><td> 2.0454000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.1466600</td><td> 0.1256500</td><td> 2.1712000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P13_D07_S139_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 8.0630000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.1839600</td><td> 0.1826900</td><td> 6.7985000</td><td> 0.0000000</td><td> 0.0000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P5_E06_S54_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 1.2437000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 0.0000000</td><td> 1.9404000</td><td> 1.3346000</td><td> 0.0186340</td><td> 0.1427400</td><td> 0.0989580</td><td> 2.6889000</td><td> 0.0000000</td><td> 3.0526000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P26_H05_S377_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 1.4957000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0662610</td><td> 0.0731350</td><td> 0.0454430</td><td> 0.0000000</td><td> 0.0172090</td><td> 2.3923000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_F12_S360_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0538060</td><td> 0.4179200</td><td> 0.1256500</td><td> 2.6383000</td><td> 0.0000000</td><td> 0.0000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_F03_S351_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 2.3068000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0690150</td><td> 0.1056800</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td></tr>\n",
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       "\t<tr><th scope=row>⋮</th><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋱</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td></tr>\n",
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       "\t<tr><th scope=row>HNSCC20_P3_G06_S78_comb</th><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 3.4060000</td><td> 0.0000000</td><td> 4.3480000</td><td> 0.0000000</td><td> 0.0000000</td><td>⋯</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0342160</td><td> 0.0000000</td><td> 0.1110300</td><td> 0.0000000</td><td> 0.0000000</td><td> 0.0000000</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A matrix: 5902 × 21813 of type chr\n",
       "\\begin{tabular}{r|lllllllllllllllllllll}\n",
       "  & ENSG00000121410 & ENSG00000268895 & ENSG00000148584 & ENSG00000175899 & ENSG00000245105 & ENSG00000166535 & ENSG00000256069 & ENSG00000128274 & ENSG00000118017 & ENSG00000265544 & ⋯ & ENSG00000174442 & ENSG00000122952 & ENSG00000198205 & ENSG00000198455 & ENSG00000070476 & ENSG00000203995 & ENSG00000162378 & ENSG00000159840 & ENSG00000074755 & ENSG00000036549\\\\\n",
       "\\hline\n",
       "\tHN28\\_P15\\_D06\\_S330\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  9.6830000 &  0.1763200 &  0.0000000 &  0.0000000 &  2.2488000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.1216800 &  0.1635000 &  0.0908530 &  4.2748000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHN28\\_P6\\_G05\\_S173\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  7.5830000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.1953500 &  0.2797700 &  3.9348000 &  0.0000000 &  3.7716000 &  0.0000000\\\\\n",
       "\tHN26\\_P14\\_D11\\_S239\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0299830 &  0.0000000 &  4.7988000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0214800 &  0.0000000 &  0.0731350 &  0.0000000 &  1.3045000 &  2.1120000\\\\\n",
       "\tHN26\\_P14\\_H05\\_S281\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  6.0547000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.2642400 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0894980 &  0.1865000 &  0.2141200 &  0.1243300 &  0.0935600 &  0.0000000\\\\\n",
       "\tHN26\\_P25\\_H09\\_S189\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  2.1385000 &  0.2289700 &  0.1335600 &  2.9059000 &  3.0034000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHN26\\_P14\\_H06\\_S282\\_comb &  0.0662610 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  2.2830000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.8718400 &  0.0000000 &  0.0000000 &  0.0000000 &  1.2016000 &  0.0635030 &  0.0510240 &  0.6050200 &  0.0000000 &  0.0000000\\\\\n",
       "\tHN25\\_P25\\_C04\\_S316\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.1966100 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.3628900 &  1.0881000 &  0.8559900 &  0.0000000 &  0.8567900 &  0.0000000\\\\\n",
       "\tHN26\\_P25\\_A11\\_S107\\_comb &  0.5410200 &  0.0000000 &  0.0000000 &  7.7060000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  4.6348000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0976110 &  0.0676390 &  0.0000000 &  5.2928000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHN26\\_P25\\_C09\\_S129\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  1.1250000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0621220 &  0.0328060 &  0.0922070 &  0.0000000 &  0.0172090 &  0.0000000\\\\\n",
       "\tHNSCC26\\_P24\\_H05\\_S377\\_comb &  1.3004000 &  0.0000000 &  0.0000000 &  0.0000000 &  2.6192000 &  0.1256500 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.6229300 &  0.2215700 &  0.4200800 &  0.5568000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHN25\\_P5\\_E10\\_S58\\_comb &  1.983300  &  0.000000  &  0.000000  &  7.285600  &  0.000000  &  0.000000  &  0.000000  &  4.445100  &  0.000000  &  0.000000  & ⋯ &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.028569  &  0.332280  &  0.313830  &  3.916600  &  0.000000  &  0.000000 \\\\\n",
       "\tHN25\\_P24\\_B02\\_S110\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  1.9505000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  3.7281000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  1.0468000 &  1.9381000 &  0.2363400 &  0.4467900\\\\\n",
       "\tHN25\\_P25\\_C01\\_S313\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.1003000 &  0.5916800 &  0.1890300 &  0.0000000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHN28\\_P15\\_G06\\_S366\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  7.8525000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  4.3319000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.3584000 &  4.3710000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHN26\\_P6\\_B06\\_S18\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  8.3136000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  7.0375000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.1230000 &  0.2215700 &  0.2545900 &  0.0000000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHN25\\_P5\\_C05\\_S29\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0496310 &  0.0000000 &  0.0000000 &  0.0000000 &  2.1496000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.7311800 &  0.0000000 &  0.0662610 &  0.0000000 &  0.6397000 &  3.1760000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHN28\\_P6\\_D09\\_S141\\_comb &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.000000  & ⋯ &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.458380  &  2.233300  &  0.000000  &  0.000000 \\\\\n",
       "\tHN26\\_P5\\_H01\\_S85\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  4.8070000 &  0.0000000 &  2.0454000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.1466600 &  0.1256500 &  2.1712000 &  0.0000000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHN26\\_P13\\_D07\\_S139\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  8.0630000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.1839600 &  0.1826900 &  6.7985000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHN26\\_P5\\_E06\\_S54\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  1.2437000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  1.9404000 &  1.3346000 &  0.0186340 &  0.1427400 &  0.0989580 &  2.6889000 &  0.0000000 &  3.0526000\\\\\n",
       "\tHN26\\_P26\\_H05\\_S377\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  1.4957000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0662610 &  0.0731350 &  0.0454430 &  0.0000000 &  0.0172090 &  2.3923000\\\\\n",
       "\tHNSCC26\\_P24\\_F12\\_S360\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0538060 &  0.4179200 &  0.1256500 &  2.6383000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHNSCC26\\_P24\\_F03\\_S351\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  2.3068000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0690150 &  0.1056800 &  0.0000000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHN26\\_P6\\_D08\\_S44\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  5.3131000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0328060 &  0.1083600 &  0.1348800 &  1.5246000 &  1.2029000 &  0.0000000\\\\\n",
       "\tHN25\\_P5\\_E12\\_S60\\_comb &  0.0000000 &  2.0635000 &  0.0000000 &  9.0809000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.5849600 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.1056800 &  0.0000000 &  0.0827030 &  3.8996000 &  1.4885000 &  0.0000000\\\\\n",
       "\tHNSCC26\\_P24\\_C01\\_S313\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  2.4681000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  3.1533000 &  0.0000000 &  0.0000000 &  0.0243200 &  0.1375000 &  0.4782000 &  0.0000000 &  1.3718000 &  1.9305000\\\\\n",
       "\tHN25\\_P5\\_F01\\_S61\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  9.7089000 &  0.0000000 &  0.1737700 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0648830 &  0.1596300 &  0.0000000 &  3.4525000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHN26\\_P5\\_D12\\_S48\\_comb &  0.000000  &  0.000000  &  0.000000  &  8.795600  &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.000000  & ⋯ &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  4.464900  &  0.735520  &  0.626670  &  5.489100  &  0.000000  &  0.000000 \\\\\n",
       "\tHN25\\_P25\\_C11\\_S323\\_comb &  0.0000000 &  0.0000000 &  0.0214800 &  4.9392000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  4.1772000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0717630 &  0.1216800 &  0.1865000 &  0.0000000 &  0.2003800 &  0.0000000\\\\\n",
       "\tHN25\\_P25\\_B12\\_S312\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0370310 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0496310 &  0.0813400 &  1.2702000 &  2.3291000 &  1.3901000 &  0.0000000\\\\\n",
       "\t⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋱ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n",
       "\tHNSCC17\\_P4\\_A08\\_S104\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  1.0349000 &  4.1908000 &  0.0000000 &  0.0000000 &  1.0072000 &  0.1401200 &  0.0635030 &  1.4114000 &  0.0257380 &  1.3357000\\\\\n",
       "\tHNSCC17\\_P4\\_E10\\_S154\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0214800 &  0.0000000 &  0.0579700 &  1.7740000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHNSCC17\\_P4\\_E02\\_S146\\_comb &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  3.012700  &  0.000000  &  0.000000  &  0.000000  &  0.000000  & ⋯ &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.591680  &  3.631600  &  0.000000  &  0.000000 \\\\\n",
       "\tHNSCC20\\_P13\\_F10\\_S262\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  4.8439000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  3.5203000\\\\\n",
       "\tHNSCC17\\_P4\\_D04\\_S136\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0635030 &  0.0000000 &  0.4340300 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  1.4782000 &  0.0229000 &  0.0676390 &  0.0328060 &  4.0441000 &  0.5058900 &  0.0000000\\\\\n",
       "\tHNSCC20\\_P13\\_C06\\_S222\\_comb &  0.0000000 &  0.0000000 &  0.0468400 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  5.4339000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.2351100 &  0.1826900 &  0.2314300 &  0.0000000 &  1.9381000 &  3.6758000\\\\\n",
       "\tHNSCC20\\_P13\\_C12\\_S228\\_comb &  1.112400  &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  2.334900  &  0.000000  &  0.000000  & ⋯ &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  1.292200  &  0.000000  &  0.718960  &  2.784700  &  0.000000  &  0.000000 \\\\\n",
       "\tHNSCC17\\_P4\\_H04\\_S184\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  1.2209000 &  0.0000000 &  0.0000000 & ⋯ &  0.5430000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.6350600 &  0.0000000 &  0.0000000\\\\\n",
       "\tHNSCC17\\_P4\\_C06\\_S126\\_comb &  0.9913200 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  1.2437000 &  0.0000000 &  0.0000000 & ⋯ &  2.2895000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.4520700 &  0.0000000 &  0.0000000 &  2.1130000 &  0.0000000 &  0.5300700\\\\\n",
       "\tHNSCC20\\_P3\\_D01\\_S37\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  4.2863000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  4.3682000 &  0.1427400 &  0.0000000 &  0.4936500 &  0.0786100 &  0.0922070 &  3.2007000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHNSCC20\\_P3\\_D09\\_S45\\_comb &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.096262  &  0.000000  &  4.383400  &  0.000000  &  0.000000  & ⋯ &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.000000  &  0.107020  &  0.000000  &  0.000000  &  0.000000  &  2.838800 \\\\\n",
       "\tHNSCC17\\_P4\\_E06\\_S150\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.5743400 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0157830 &  0.1322500 &  0.0000000 &  3.7401000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHNSCC20\\_P13\\_H10\\_S286\\_comb &  0.0000000 &  0.0000000 &  0.0482360 &  0.0000000 &  0.0000000 &  3.0342000 &  0.0000000 &  4.0526000 &  0.0000000 &  0.0000000 & ⋯ &  3.3990000 &  5.6353000 &  0.0000000 &  0.0000000 &  0.0398400 &  1.0065000 &  0.0565840 &  0.0000000 &  0.0000000 &  3.6434000\\\\\n",
       "\tHNSCC17\\_P4\\_A02\\_S98\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.1388100 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.1414300 &  0.1479600 &  0.1492600 &  4.1065000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHNSCC20\\_P13\\_D01\\_S229\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  5.2244000 &  0.0000000 &  0.0000000 & ⋯ &  3.0659000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0635030 &  0.0000000 &  0.0000000 &  0.0000000 &  1.4233000 &  0.0000000\\\\\n",
       "\tHNSCC20\\_P13\\_G02\\_S266\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  4.1467000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0827030 &  0.0000000 &  0.0662610 &  0.2461000 &  0.1096900 &  0.0000000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHNSCC17\\_P4\\_B04\\_S112\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  3.5795000 &  4.5380000 &  0.0000000 &  0.0000000 &  1.9149000 &  0.0538060 &  0.1070200 &  0.9478500 &  0.0000000 &  0.0000000\\\\\n",
       "\tHNSCC17\\_P4\\_C09\\_S129\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  2.5654000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  3.1090000 &  0.0551960 &  0.0662610 &  4.2718000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHNSCC20\\_P13\\_A12\\_S204\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  5.3083000 &  0.0000000 &  3.6502000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0772430 &  0.0000000 &  0.0000000 &  0.1940900 &  1.1909000 &  1.1744000\\\\\n",
       "\tHNSCC17\\_P4\\_F06\\_S162\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  4.6224000 &  0.0000000 &  0.0000000 &  0.2448900 &  0.1163600 &  0.1177000 &  0.0000000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHNSCC20\\_P3\\_B10\\_S22\\_comb &  0.6332000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.3115000 &  0.0000000 &  5.1809000 &  0.0000000 &  0.0000000 & ⋯ &  1.5514000 &  3.0491000 &  0.0000000 &  0.7092900 &  1.4415000 &  0.0000000 &  0.7372500 &  3.3828000 &  0.1070200 &  2.2333000\\\\\n",
       "\tHNSCC20\\_P13\\_B11\\_S215\\_comb &  1.2259000 &  1.0642000 &  0.0000000 &  0.0000000 &  0.0000000 &  5.7351000 &  0.0000000 &  3.6552000 &  0.0000000 &  0.0000000 & ⋯ &  2.8852000 &  4.5492000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.2016300 &  0.0000000 &  1.0007000 &  0.5753100 &  1.6808000\\\\\n",
       "\tHNSCC20\\_P3\\_C08\\_S32\\_comb &  1.3774000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  5.0575000 &  0.0000000 &  0.0000000 & ⋯ &  2.1220000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0412430 &  0.0000000 &  0.0000000 &  2.5243000 &  0.1724900 &  0.0000000\\\\\n",
       "\tHNSCC17\\_P4\\_H03\\_S183\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  4.5356000 &  0.0000000 &  0.0000000 &  0.0129260 &  0.0000000 &  0.0370310 &  0.0000000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHNSCC20\\_P3\\_F09\\_S69\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  2.6889000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.6069200 &  0.0000000 &  0.0398400 &  0.6771700 &  1.0179000 &  0.0717630\\\\\n",
       "\tHNSCC17\\_P4\\_G12\\_S180\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  4.1886000 &  0.3983500 &  0.2545900 &  0.7527500 &  0.0000000 &  0.0000000\\\\\n",
       "\tHNSCC20\\_P13\\_C05\\_S221\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  5.0877000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.2473200 &  0.7467400 &  0.3184600 &  0.0000000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHNSCC17\\_P4\\_C12\\_S132\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0426440 &  0.0000000 &  1.8111000 &  0.0000000 &  0.0000000 & ⋯ &  0.1016500 &  3.4737000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  2.1063000 &  4.0557000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHNSCC20\\_P3\\_H08\\_S92\\_comb &  2.9996000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  3.8370000 &  0.0000000 &  0.0000000 & ⋯ &  3.5969000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.1570400 &  0.2363400 &  0.2916000 &  3.7342000 &  0.0000000 &  0.0000000\\\\\n",
       "\tHNSCC20\\_P3\\_G06\\_S78\\_comb &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  3.4060000 &  0.0000000 &  4.3480000 &  0.0000000 &  0.0000000 & ⋯ &  0.0000000 &  0.0000000 &  0.0000000 &  0.0000000 &  0.0342160 &  0.0000000 &  0.1110300 &  0.0000000 &  0.0000000 &  0.0000000\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A matrix: 5902 × 21813 of type chr\n",
       "\n",
       "| <!--/--> | ENSG00000121410 | ENSG00000268895 | ENSG00000148584 | ENSG00000175899 | ENSG00000245105 | ENSG00000166535 | ENSG00000256069 | ENSG00000128274 | ENSG00000118017 | ENSG00000265544 | ⋯ | ENSG00000174442 | ENSG00000122952 | ENSG00000198205 | ENSG00000198455 | ENSG00000070476 | ENSG00000203995 | ENSG00000162378 | ENSG00000159840 | ENSG00000074755 | ENSG00000036549 |\n",
       "|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|\n",
       "| HN28_P15_D06_S330_comb |  0.0000000 |  0.0000000 |  0.0000000 |  9.6830000 |  0.1763200 |  0.0000000 |  0.0000000 |  2.2488000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.1216800 |  0.1635000 |  0.0908530 |  4.2748000 |  0.0000000 |  0.0000000 |\n",
       "| HN28_P6_G05_S173_comb |  0.0000000 |  0.0000000 |  0.0000000 |  7.5830000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.1953500 |  0.2797700 |  3.9348000 |  0.0000000 |  3.7716000 |  0.0000000 |\n",
       "| HN26_P14_D11_S239_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0299830 |  0.0000000 |  4.7988000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0214800 |  0.0000000 |  0.0731350 |  0.0000000 |  1.3045000 |  2.1120000 |\n",
       "| HN26_P14_H05_S281_comb |  0.0000000 |  0.0000000 |  0.0000000 |  6.0547000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.2642400 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0894980 |  0.1865000 |  0.2141200 |  0.1243300 |  0.0935600 |  0.0000000 |\n",
       "| HN26_P25_H09_S189_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  2.1385000 |  0.2289700 |  0.1335600 |  2.9059000 |  3.0034000 |  0.0000000 |  0.0000000 |\n",
       "| HN26_P14_H06_S282_comb |  0.0662610 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  2.2830000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.8718400 |  0.0000000 |  0.0000000 |  0.0000000 |  1.2016000 |  0.0635030 |  0.0510240 |  0.6050200 |  0.0000000 |  0.0000000 |\n",
       "| HN25_P25_C04_S316_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.1966100 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.3628900 |  1.0881000 |  0.8559900 |  0.0000000 |  0.8567900 |  0.0000000 |\n",
       "| HN26_P25_A11_S107_comb |  0.5410200 |  0.0000000 |  0.0000000 |  7.7060000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  4.6348000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0976110 |  0.0676390 |  0.0000000 |  5.2928000 |  0.0000000 |  0.0000000 |\n",
       "| HN26_P25_C09_S129_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  1.1250000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0621220 |  0.0328060 |  0.0922070 |  0.0000000 |  0.0172090 |  0.0000000 |\n",
       "| HNSCC26_P24_H05_S377_comb |  1.3004000 |  0.0000000 |  0.0000000 |  0.0000000 |  2.6192000 |  0.1256500 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.6229300 |  0.2215700 |  0.4200800 |  0.5568000 |  0.0000000 |  0.0000000 |\n",
       "| HN25_P5_E10_S58_comb |  1.983300  |  0.000000  |  0.000000  |  7.285600  |  0.000000  |  0.000000  |  0.000000  |  4.445100  |  0.000000  |  0.000000  | ⋯ |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.028569  |  0.332280  |  0.313830  |  3.916600  |  0.000000  |  0.000000  |\n",
       "| HN25_P24_B02_S110_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  1.9505000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  3.7281000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  1.0468000 |  1.9381000 |  0.2363400 |  0.4467900 |\n",
       "| HN25_P25_C01_S313_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.1003000 |  0.5916800 |  0.1890300 |  0.0000000 |  0.0000000 |  0.0000000 |\n",
       "| HN28_P15_G06_S366_comb |  0.0000000 |  0.0000000 |  0.0000000 |  7.8525000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  4.3319000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.3584000 |  4.3710000 |  0.0000000 |  0.0000000 |\n",
       "| HN26_P6_B06_S18_comb |  0.0000000 |  0.0000000 |  0.0000000 |  8.3136000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  7.0375000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.1230000 |  0.2215700 |  0.2545900 |  0.0000000 |  0.0000000 |  0.0000000 |\n",
       "| HN25_P5_C05_S29_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0496310 |  0.0000000 |  0.0000000 |  0.0000000 |  2.1496000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.7311800 |  0.0000000 |  0.0662610 |  0.0000000 |  0.6397000 |  3.1760000 |  0.0000000 |  0.0000000 |\n",
       "| HN28_P6_D09_S141_comb |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.000000  | ⋯ |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.458380  |  2.233300  |  0.000000  |  0.000000  |\n",
       "| HN26_P5_H01_S85_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  4.8070000 |  0.0000000 |  2.0454000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.1466600 |  0.1256500 |  2.1712000 |  0.0000000 |  0.0000000 |  0.0000000 |\n",
       "| HN26_P13_D07_S139_comb |  0.0000000 |  0.0000000 |  0.0000000 |  8.0630000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.1839600 |  0.1826900 |  6.7985000 |  0.0000000 |  0.0000000 |\n",
       "| HN26_P5_E06_S54_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  1.2437000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  1.9404000 |  1.3346000 |  0.0186340 |  0.1427400 |  0.0989580 |  2.6889000 |  0.0000000 |  3.0526000 |\n",
       "| HN26_P26_H05_S377_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  1.4957000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0662610 |  0.0731350 |  0.0454430 |  0.0000000 |  0.0172090 |  2.3923000 |\n",
       "| HNSCC26_P24_F12_S360_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0538060 |  0.4179200 |  0.1256500 |  2.6383000 |  0.0000000 |  0.0000000 |\n",
       "| HNSCC26_P24_F03_S351_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  2.3068000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0690150 |  0.1056800 |  0.0000000 |  0.0000000 |  0.0000000 |\n",
       "| HN26_P6_D08_S44_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  5.3131000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0328060 |  0.1083600 |  0.1348800 |  1.5246000 |  1.2029000 |  0.0000000 |\n",
       "| HN25_P5_E12_S60_comb |  0.0000000 |  2.0635000 |  0.0000000 |  9.0809000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.5849600 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.1056800 |  0.0000000 |  0.0827030 |  3.8996000 |  1.4885000 |  0.0000000 |\n",
       "| HNSCC26_P24_C01_S313_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  2.4681000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  3.1533000 |  0.0000000 |  0.0000000 |  0.0243200 |  0.1375000 |  0.4782000 |  0.0000000 |  1.3718000 |  1.9305000 |\n",
       "| HN25_P5_F01_S61_comb |  0.0000000 |  0.0000000 |  0.0000000 |  9.7089000 |  0.0000000 |  0.1737700 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0648830 |  0.1596300 |  0.0000000 |  3.4525000 |  0.0000000 |  0.0000000 |\n",
       "| HN26_P5_D12_S48_comb |  0.000000  |  0.000000  |  0.000000  |  8.795600  |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.000000  | ⋯ |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  4.464900  |  0.735520  |  0.626670  |  5.489100  |  0.000000  |  0.000000  |\n",
       "| HN25_P25_C11_S323_comb |  0.0000000 |  0.0000000 |  0.0214800 |  4.9392000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  4.1772000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0717630 |  0.1216800 |  0.1865000 |  0.0000000 |  0.2003800 |  0.0000000 |\n",
       "| HN25_P25_B12_S312_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0370310 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0496310 |  0.0813400 |  1.2702000 |  2.3291000 |  1.3901000 |  0.0000000 |\n",
       "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋱ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ |\n",
       "| HNSCC17_P4_A08_S104_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  1.0349000 |  4.1908000 |  0.0000000 |  0.0000000 |  1.0072000 |  0.1401200 |  0.0635030 |  1.4114000 |  0.0257380 |  1.3357000 |\n",
       "| HNSCC17_P4_E10_S154_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0214800 |  0.0000000 |  0.0579700 |  1.7740000 |  0.0000000 |  0.0000000 |\n",
       "| HNSCC17_P4_E02_S146_comb |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  3.012700  |  0.000000  |  0.000000  |  0.000000  |  0.000000  | ⋯ |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.591680  |  3.631600  |  0.000000  |  0.000000  |\n",
       "| HNSCC20_P13_F10_S262_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  4.8439000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  3.5203000 |\n",
       "| HNSCC17_P4_D04_S136_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0635030 |  0.0000000 |  0.4340300 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  1.4782000 |  0.0229000 |  0.0676390 |  0.0328060 |  4.0441000 |  0.5058900 |  0.0000000 |\n",
       "| HNSCC20_P13_C06_S222_comb |  0.0000000 |  0.0000000 |  0.0468400 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  5.4339000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.2351100 |  0.1826900 |  0.2314300 |  0.0000000 |  1.9381000 |  3.6758000 |\n",
       "| HNSCC20_P13_C12_S228_comb |  1.112400  |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  2.334900  |  0.000000  |  0.000000  | ⋯ |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  1.292200  |  0.000000  |  0.718960  |  2.784700  |  0.000000  |  0.000000  |\n",
       "| HNSCC17_P4_H04_S184_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  1.2209000 |  0.0000000 |  0.0000000 | ⋯ |  0.5430000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.6350600 |  0.0000000 |  0.0000000 |\n",
       "| HNSCC17_P4_C06_S126_comb |  0.9913200 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  1.2437000 |  0.0000000 |  0.0000000 | ⋯ |  2.2895000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.4520700 |  0.0000000 |  0.0000000 |  2.1130000 |  0.0000000 |  0.5300700 |\n",
       "| HNSCC20_P3_D01_S37_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  4.2863000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  4.3682000 |  0.1427400 |  0.0000000 |  0.4936500 |  0.0786100 |  0.0922070 |  3.2007000 |  0.0000000 |  0.0000000 |\n",
       "| HNSCC20_P3_D09_S45_comb |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.096262  |  0.000000  |  4.383400  |  0.000000  |  0.000000  | ⋯ |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.000000  |  0.107020  |  0.000000  |  0.000000  |  0.000000  |  2.838800  |\n",
       "| HNSCC17_P4_E06_S150_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.5743400 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0157830 |  0.1322500 |  0.0000000 |  3.7401000 |  0.0000000 |  0.0000000 |\n",
       "| HNSCC20_P13_H10_S286_comb |  0.0000000 |  0.0000000 |  0.0482360 |  0.0000000 |  0.0000000 |  3.0342000 |  0.0000000 |  4.0526000 |  0.0000000 |  0.0000000 | ⋯ |  3.3990000 |  5.6353000 |  0.0000000 |  0.0000000 |  0.0398400 |  1.0065000 |  0.0565840 |  0.0000000 |  0.0000000 |  3.6434000 |\n",
       "| HNSCC17_P4_A02_S98_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.1388100 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.1414300 |  0.1479600 |  0.1492600 |  4.1065000 |  0.0000000 |  0.0000000 |\n",
       "| HNSCC20_P13_D01_S229_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  5.2244000 |  0.0000000 |  0.0000000 | ⋯ |  3.0659000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0635030 |  0.0000000 |  0.0000000 |  0.0000000 |  1.4233000 |  0.0000000 |\n",
       "| HNSCC20_P13_G02_S266_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  4.1467000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0827030 |  0.0000000 |  0.0662610 |  0.2461000 |  0.1096900 |  0.0000000 |  0.0000000 |  0.0000000 |\n",
       "| HNSCC17_P4_B04_S112_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  3.5795000 |  4.5380000 |  0.0000000 |  0.0000000 |  1.9149000 |  0.0538060 |  0.1070200 |  0.9478500 |  0.0000000 |  0.0000000 |\n",
       "| HNSCC17_P4_C09_S129_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  2.5654000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  3.1090000 |  0.0551960 |  0.0662610 |  4.2718000 |  0.0000000 |  0.0000000 |\n",
       "| HNSCC20_P13_A12_S204_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  5.3083000 |  0.0000000 |  3.6502000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0772430 |  0.0000000 |  0.0000000 |  0.1940900 |  1.1909000 |  1.1744000 |\n",
       "| HNSCC17_P4_F06_S162_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  4.6224000 |  0.0000000 |  0.0000000 |  0.2448900 |  0.1163600 |  0.1177000 |  0.0000000 |  0.0000000 |  0.0000000 |\n",
       "| HNSCC20_P3_B10_S22_comb |  0.6332000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.3115000 |  0.0000000 |  5.1809000 |  0.0000000 |  0.0000000 | ⋯ |  1.5514000 |  3.0491000 |  0.0000000 |  0.7092900 |  1.4415000 |  0.0000000 |  0.7372500 |  3.3828000 |  0.1070200 |  2.2333000 |\n",
       "| HNSCC20_P13_B11_S215_comb |  1.2259000 |  1.0642000 |  0.0000000 |  0.0000000 |  0.0000000 |  5.7351000 |  0.0000000 |  3.6552000 |  0.0000000 |  0.0000000 | ⋯ |  2.8852000 |  4.5492000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.2016300 |  0.0000000 |  1.0007000 |  0.5753100 |  1.6808000 |\n",
       "| HNSCC20_P3_C08_S32_comb |  1.3774000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  5.0575000 |  0.0000000 |  0.0000000 | ⋯ |  2.1220000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0412430 |  0.0000000 |  0.0000000 |  2.5243000 |  0.1724900 |  0.0000000 |\n",
       "| HNSCC17_P4_H03_S183_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  4.5356000 |  0.0000000 |  0.0000000 |  0.0129260 |  0.0000000 |  0.0370310 |  0.0000000 |  0.0000000 |  0.0000000 |\n",
       "| HNSCC20_P3_F09_S69_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  2.6889000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.6069200 |  0.0000000 |  0.0398400 |  0.6771700 |  1.0179000 |  0.0717630 |\n",
       "| HNSCC17_P4_G12_S180_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  4.1886000 |  0.3983500 |  0.2545900 |  0.7527500 |  0.0000000 |  0.0000000 |\n",
       "| HNSCC20_P13_C05_S221_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  5.0877000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.2473200 |  0.7467400 |  0.3184600 |  0.0000000 |  0.0000000 |  0.0000000 |\n",
       "| HNSCC17_P4_C12_S132_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0426440 |  0.0000000 |  1.8111000 |  0.0000000 |  0.0000000 | ⋯ |  0.1016500 |  3.4737000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  2.1063000 |  4.0557000 |  0.0000000 |  0.0000000 |\n",
       "| HNSCC20_P3_H08_S92_comb |  2.9996000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  3.8370000 |  0.0000000 |  0.0000000 | ⋯ |  3.5969000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.1570400 |  0.2363400 |  0.2916000 |  3.7342000 |  0.0000000 |  0.0000000 |\n",
       "| HNSCC20_P3_G06_S78_comb |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  3.4060000 |  0.0000000 |  4.3480000 |  0.0000000 |  0.0000000 | ⋯ |  0.0000000 |  0.0000000 |  0.0000000 |  0.0000000 |  0.0342160 |  0.0000000 |  0.1110300 |  0.0000000 |  0.0000000 |  0.0000000 |\n",
       "\n"
      ],
      "text/plain": [
       "                          ENSG00000121410 ENSG00000268895 ENSG00000148584\n",
       "HN28_P15_D06_S330_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN28_P6_G05_S173_comb      0.0000000       0.0000000       0.0000000     \n",
       "HN26_P14_D11_S239_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN26_P14_H05_S281_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN26_P25_H09_S189_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN26_P14_H06_S282_comb     0.0662610       0.0000000       0.0000000     \n",
       "HN25_P25_C04_S316_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN26_P25_A11_S107_comb     0.5410200       0.0000000       0.0000000     \n",
       "HN26_P25_C09_S129_comb     0.0000000       0.0000000       0.0000000     \n",
       "HNSCC26_P24_H05_S377_comb  1.3004000       0.0000000       0.0000000     \n",
       "HN25_P5_E10_S58_comb       1.983300        0.000000        0.000000      \n",
       "HN25_P24_B02_S110_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN25_P25_C01_S313_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN28_P15_G06_S366_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN26_P6_B06_S18_comb       0.0000000       0.0000000       0.0000000     \n",
       "HN25_P5_C05_S29_comb       0.0000000       0.0000000       0.0000000     \n",
       "HN28_P6_D09_S141_comb      0.000000        0.000000        0.000000      \n",
       "HN26_P5_H01_S85_comb       0.0000000       0.0000000       0.0000000     \n",
       "HN26_P13_D07_S139_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN26_P5_E06_S54_comb       0.0000000       0.0000000       0.0000000     \n",
       "HN26_P26_H05_S377_comb     0.0000000       0.0000000       0.0000000     \n",
       "HNSCC26_P24_F12_S360_comb  0.0000000       0.0000000       0.0000000     \n",
       "HNSCC26_P24_F03_S351_comb  0.0000000       0.0000000       0.0000000     \n",
       "HN26_P6_D08_S44_comb       0.0000000       0.0000000       0.0000000     \n",
       "HN25_P5_E12_S60_comb       0.0000000       2.0635000       0.0000000     \n",
       "HNSCC26_P24_C01_S313_comb  0.0000000       0.0000000       0.0000000     \n",
       "HN25_P5_F01_S61_comb       0.0000000       0.0000000       0.0000000     \n",
       "HN26_P5_D12_S48_comb       0.000000        0.000000        0.000000      \n",
       "HN25_P25_C11_S323_comb     0.0000000       0.0000000       0.0214800     \n",
       "HN25_P25_B12_S312_comb     0.0000000       0.0000000       0.0000000     \n",
       "⋮                         ⋮               ⋮               ⋮              \n",
       "HNSCC17_P4_A08_S104_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_E10_S154_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_E02_S146_comb   0.000000        0.000000        0.000000      \n",
       "HNSCC20_P13_F10_S262_comb  0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_D04_S136_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P13_C06_S222_comb  0.0000000       0.0000000       0.0468400     \n",
       "HNSCC20_P13_C12_S228_comb  1.112400        0.000000        0.000000      \n",
       "HNSCC17_P4_H04_S184_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_C06_S126_comb   0.9913200       0.0000000       0.0000000     \n",
       "HNSCC20_P3_D01_S37_comb    0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P3_D09_S45_comb    0.000000        0.000000        0.000000      \n",
       "HNSCC17_P4_E06_S150_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P13_H10_S286_comb  0.0000000       0.0000000       0.0482360     \n",
       "HNSCC17_P4_A02_S98_comb    0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P13_D01_S229_comb  0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P13_G02_S266_comb  0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_B04_S112_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_C09_S129_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P13_A12_S204_comb  0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_F06_S162_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P3_B10_S22_comb    0.6332000       0.0000000       0.0000000     \n",
       "HNSCC20_P13_B11_S215_comb  1.2259000       1.0642000       0.0000000     \n",
       "HNSCC20_P3_C08_S32_comb    1.3774000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_H03_S183_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P3_F09_S69_comb    0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_G12_S180_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P13_C05_S221_comb  0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_C12_S132_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P3_H08_S92_comb    2.9996000       0.0000000       0.0000000     \n",
       "HNSCC20_P3_G06_S78_comb    0.0000000       0.0000000       0.0000000     \n",
       "                          ENSG00000175899 ENSG00000245105 ENSG00000166535\n",
       "HN28_P15_D06_S330_comb     9.6830000       0.1763200       0.0000000     \n",
       "HN28_P6_G05_S173_comb      7.5830000       0.0000000       0.0000000     \n",
       "HN26_P14_D11_S239_comb     0.0299830       0.0000000       4.7988000     \n",
       "HN26_P14_H05_S281_comb     6.0547000       0.0000000       0.0000000     \n",
       "HN26_P25_H09_S189_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN26_P14_H06_S282_comb     0.0000000       0.0000000       2.2830000     \n",
       "HN25_P25_C04_S316_comb     0.1966100       0.0000000       0.0000000     \n",
       "HN26_P25_A11_S107_comb     7.7060000       0.0000000       0.0000000     \n",
       "HN26_P25_C09_S129_comb     0.0000000       0.0000000       1.1250000     \n",
       "HNSCC26_P24_H05_S377_comb  0.0000000       2.6192000       0.1256500     \n",
       "HN25_P5_E10_S58_comb       7.285600        0.000000        0.000000      \n",
       "HN25_P24_B02_S110_comb     0.0000000       0.0000000       1.9505000     \n",
       "HN25_P25_C01_S313_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN28_P15_G06_S366_comb     7.8525000       0.0000000       0.0000000     \n",
       "HN26_P6_B06_S18_comb       8.3136000       0.0000000       0.0000000     \n",
       "HN25_P5_C05_S29_comb       0.0496310       0.0000000       0.0000000     \n",
       "HN28_P6_D09_S141_comb      0.000000        0.000000        0.000000      \n",
       "HN26_P5_H01_S85_comb       0.0000000       0.0000000       4.8070000     \n",
       "HN26_P13_D07_S139_comb     8.0630000       0.0000000       0.0000000     \n",
       "HN26_P5_E06_S54_comb       0.0000000       0.0000000       0.0000000     \n",
       "HN26_P26_H05_S377_comb     0.0000000       0.0000000       1.4957000     \n",
       "HNSCC26_P24_F12_S360_comb  0.0000000       0.0000000       0.0000000     \n",
       "HNSCC26_P24_F03_S351_comb  0.0000000       0.0000000       0.0000000     \n",
       "HN26_P6_D08_S44_comb       0.0000000       0.0000000       5.3131000     \n",
       "HN25_P5_E12_S60_comb       9.0809000       0.0000000       0.0000000     \n",
       "HNSCC26_P24_C01_S313_comb  0.0000000       0.0000000       2.4681000     \n",
       "HN25_P5_F01_S61_comb       9.7089000       0.0000000       0.1737700     \n",
       "HN26_P5_D12_S48_comb       8.795600        0.000000        0.000000      \n",
       "HN25_P25_C11_S323_comb     4.9392000       0.0000000       0.0000000     \n",
       "HN25_P25_B12_S312_comb     0.0000000       0.0000000       0.0370310     \n",
       "⋮                         ⋮               ⋮               ⋮              \n",
       "HNSCC17_P4_A08_S104_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_E10_S154_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_E02_S146_comb   0.000000        0.000000        3.012700      \n",
       "HNSCC20_P13_F10_S262_comb  0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_D04_S136_comb   0.0000000       0.0000000       0.0635030     \n",
       "HNSCC20_P13_C06_S222_comb  0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P13_C12_S228_comb  0.000000        0.000000        0.000000      \n",
       "HNSCC17_P4_H04_S184_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_C06_S126_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P3_D01_S37_comb    0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P3_D09_S45_comb    0.000000        0.000000        0.096262      \n",
       "HNSCC17_P4_E06_S150_comb   0.0000000       0.0000000       0.5743400     \n",
       "HNSCC20_P13_H10_S286_comb  0.0000000       0.0000000       3.0342000     \n",
       "HNSCC17_P4_A02_S98_comb    0.0000000       0.0000000       0.1388100     \n",
       "HNSCC20_P13_D01_S229_comb  0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P13_G02_S266_comb  0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_B04_S112_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_C09_S129_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P13_A12_S204_comb  0.0000000       0.0000000       5.3083000     \n",
       "HNSCC17_P4_F06_S162_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P3_B10_S22_comb    0.0000000       0.0000000       0.3115000     \n",
       "HNSCC20_P13_B11_S215_comb  0.0000000       0.0000000       5.7351000     \n",
       "HNSCC20_P3_C08_S32_comb    0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_H03_S183_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P3_F09_S69_comb    0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_G12_S180_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P13_C05_S221_comb  0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_C12_S132_comb   0.0000000       0.0000000       0.0426440     \n",
       "HNSCC20_P3_H08_S92_comb    0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P3_G06_S78_comb    0.0000000       0.0000000       3.4060000     \n",
       "                          ENSG00000256069 ENSG00000128274 ENSG00000118017\n",
       "HN28_P15_D06_S330_comb     0.0000000       2.2488000       0.0000000     \n",
       "HN28_P6_G05_S173_comb      0.0000000       0.0000000       0.0000000     \n",
       "HN26_P14_D11_S239_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN26_P14_H05_S281_comb     0.0000000       0.2642400       0.0000000     \n",
       "HN26_P25_H09_S189_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN26_P14_H06_S282_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN25_P25_C04_S316_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN26_P25_A11_S107_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN26_P25_C09_S129_comb     0.0000000       0.0000000       0.0000000     \n",
       "HNSCC26_P24_H05_S377_comb  0.0000000       0.0000000       0.0000000     \n",
       "HN25_P5_E10_S58_comb       0.000000        4.445100        0.000000      \n",
       "HN25_P24_B02_S110_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN25_P25_C01_S313_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN28_P15_G06_S366_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN26_P6_B06_S18_comb       0.0000000       0.0000000       0.0000000     \n",
       "HN25_P5_C05_S29_comb       0.0000000       2.1496000       0.0000000     \n",
       "HN28_P6_D09_S141_comb      0.000000        0.000000        0.000000      \n",
       "HN26_P5_H01_S85_comb       0.0000000       2.0454000       0.0000000     \n",
       "HN26_P13_D07_S139_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN26_P5_E06_S54_comb       0.0000000       1.2437000       0.0000000     \n",
       "HN26_P26_H05_S377_comb     0.0000000       0.0000000       0.0000000     \n",
       "HNSCC26_P24_F12_S360_comb  0.0000000       0.0000000       0.0000000     \n",
       "HNSCC26_P24_F03_S351_comb  0.0000000       2.3068000       0.0000000     \n",
       "HN26_P6_D08_S44_comb       0.0000000       0.0000000       0.0000000     \n",
       "HN25_P5_E12_S60_comb       0.0000000       0.5849600       0.0000000     \n",
       "HNSCC26_P24_C01_S313_comb  0.0000000       0.0000000       0.0000000     \n",
       "HN25_P5_F01_S61_comb       0.0000000       0.0000000       0.0000000     \n",
       "HN26_P5_D12_S48_comb       0.000000        0.000000        0.000000      \n",
       "HN25_P25_C11_S323_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN25_P25_B12_S312_comb     0.0000000       0.0000000       0.0000000     \n",
       "⋮                         ⋮               ⋮               ⋮              \n",
       "HNSCC17_P4_A08_S104_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_E10_S154_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_E02_S146_comb   0.000000        0.000000        0.000000      \n",
       "HNSCC20_P13_F10_S262_comb  0.0000000       4.8439000       0.0000000     \n",
       "HNSCC17_P4_D04_S136_comb   0.0000000       0.4340300       0.0000000     \n",
       "HNSCC20_P13_C06_S222_comb  0.0000000       5.4339000       0.0000000     \n",
       "HNSCC20_P13_C12_S228_comb  0.000000        2.334900        0.000000      \n",
       "HNSCC17_P4_H04_S184_comb   0.0000000       1.2209000       0.0000000     \n",
       "HNSCC17_P4_C06_S126_comb   0.0000000       1.2437000       0.0000000     \n",
       "HNSCC20_P3_D01_S37_comb    0.0000000       4.2863000       0.0000000     \n",
       "HNSCC20_P3_D09_S45_comb    0.000000        4.383400        0.000000      \n",
       "HNSCC17_P4_E06_S150_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P13_H10_S286_comb  0.0000000       4.0526000       0.0000000     \n",
       "HNSCC17_P4_A02_S98_comb    0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P13_D01_S229_comb  0.0000000       5.2244000       0.0000000     \n",
       "HNSCC20_P13_G02_S266_comb  0.0000000       4.1467000       0.0000000     \n",
       "HNSCC17_P4_B04_S112_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_C09_S129_comb   0.0000000       2.5654000       0.0000000     \n",
       "HNSCC20_P13_A12_S204_comb  0.0000000       3.6502000       0.0000000     \n",
       "HNSCC17_P4_F06_S162_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P3_B10_S22_comb    0.0000000       5.1809000       0.0000000     \n",
       "HNSCC20_P13_B11_S215_comb  0.0000000       3.6552000       0.0000000     \n",
       "HNSCC20_P3_C08_S32_comb    0.0000000       5.0575000       0.0000000     \n",
       "HNSCC17_P4_H03_S183_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P3_F09_S69_comb    0.0000000       2.6889000       0.0000000     \n",
       "HNSCC17_P4_G12_S180_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P13_C05_S221_comb  0.0000000       5.0877000       0.0000000     \n",
       "HNSCC17_P4_C12_S132_comb   0.0000000       1.8111000       0.0000000     \n",
       "HNSCC20_P3_H08_S92_comb    0.0000000       3.8370000       0.0000000     \n",
       "HNSCC20_P3_G06_S78_comb    0.0000000       4.3480000       0.0000000     \n",
       "                          ENSG00000265544 ⋯ ENSG00000174442 ENSG00000122952\n",
       "HN28_P15_D06_S330_comb     0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HN28_P6_G05_S173_comb      0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HN26_P14_D11_S239_comb     0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HN26_P14_H05_S281_comb     0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HN26_P25_H09_S189_comb     0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HN26_P14_H06_S282_comb     0.0000000      ⋯  0.8718400       0.0000000     \n",
       "HN25_P25_C04_S316_comb     0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HN26_P25_A11_S107_comb     0.0000000      ⋯  4.6348000       0.0000000     \n",
       "HN26_P25_C09_S129_comb     0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HNSCC26_P24_H05_S377_comb  0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HN25_P5_E10_S58_comb       0.000000       ⋯  0.000000        0.000000      \n",
       "HN25_P24_B02_S110_comb     0.0000000      ⋯  0.0000000       3.7281000     \n",
       "HN25_P25_C01_S313_comb     0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HN28_P15_G06_S366_comb     0.0000000      ⋯  0.0000000       4.3319000     \n",
       "HN26_P6_B06_S18_comb       0.0000000      ⋯  7.0375000       0.0000000     \n",
       "HN25_P5_C05_S29_comb       0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HN28_P6_D09_S141_comb      0.000000       ⋯  0.000000        0.000000      \n",
       "HN26_P5_H01_S85_comb       0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HN26_P13_D07_S139_comb     0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HN26_P5_E06_S54_comb       0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HN26_P26_H05_S377_comb     0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HNSCC26_P24_F12_S360_comb  0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HNSCC26_P24_F03_S351_comb  0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HN26_P6_D08_S44_comb       0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HN25_P5_E12_S60_comb       0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HNSCC26_P24_C01_S313_comb  0.0000000      ⋯  0.0000000       3.1533000     \n",
       "HN25_P5_F01_S61_comb       0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HN26_P5_D12_S48_comb       0.000000       ⋯  0.000000        0.000000      \n",
       "HN25_P25_C11_S323_comb     0.0000000      ⋯  4.1772000       0.0000000     \n",
       "HN25_P25_B12_S312_comb     0.0000000      ⋯  0.0000000       0.0000000     \n",
       "⋮                         ⋮               ⋱ ⋮               ⋮              \n",
       "HNSCC17_P4_A08_S104_comb   0.0000000      ⋯  1.0349000       4.1908000     \n",
       "HNSCC17_P4_E10_S154_comb   0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HNSCC17_P4_E02_S146_comb   0.000000       ⋯  0.000000        0.000000      \n",
       "HNSCC20_P13_F10_S262_comb  0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HNSCC17_P4_D04_S136_comb   0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HNSCC20_P13_C06_S222_comb  0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HNSCC20_P13_C12_S228_comb  0.000000       ⋯  0.000000        0.000000      \n",
       "HNSCC17_P4_H04_S184_comb   0.0000000      ⋯  0.5430000       0.0000000     \n",
       "HNSCC17_P4_C06_S126_comb   0.0000000      ⋯  2.2895000       0.0000000     \n",
       "HNSCC20_P3_D01_S37_comb    0.0000000      ⋯  0.0000000       4.3682000     \n",
       "HNSCC20_P3_D09_S45_comb    0.000000       ⋯  0.000000        0.000000      \n",
       "HNSCC17_P4_E06_S150_comb   0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HNSCC20_P13_H10_S286_comb  0.0000000      ⋯  3.3990000       5.6353000     \n",
       "HNSCC17_P4_A02_S98_comb    0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HNSCC20_P13_D01_S229_comb  0.0000000      ⋯  3.0659000       0.0000000     \n",
       "HNSCC20_P13_G02_S266_comb  0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HNSCC17_P4_B04_S112_comb   0.0000000      ⋯  3.5795000       4.5380000     \n",
       "HNSCC17_P4_C09_S129_comb   0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HNSCC20_P13_A12_S204_comb  0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HNSCC17_P4_F06_S162_comb   0.0000000      ⋯  0.0000000       4.6224000     \n",
       "HNSCC20_P3_B10_S22_comb    0.0000000      ⋯  1.5514000       3.0491000     \n",
       "HNSCC20_P13_B11_S215_comb  0.0000000      ⋯  2.8852000       4.5492000     \n",
       "HNSCC20_P3_C08_S32_comb    0.0000000      ⋯  2.1220000       0.0000000     \n",
       "HNSCC17_P4_H03_S183_comb   0.0000000      ⋯  0.0000000       4.5356000     \n",
       "HNSCC20_P3_F09_S69_comb    0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HNSCC17_P4_G12_S180_comb   0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HNSCC20_P13_C05_S221_comb  0.0000000      ⋯  0.0000000       0.0000000     \n",
       "HNSCC17_P4_C12_S132_comb   0.0000000      ⋯  0.1016500       3.4737000     \n",
       "HNSCC20_P3_H08_S92_comb    0.0000000      ⋯  3.5969000       0.0000000     \n",
       "HNSCC20_P3_G06_S78_comb    0.0000000      ⋯  0.0000000       0.0000000     \n",
       "                          ENSG00000198205 ENSG00000198455 ENSG00000070476\n",
       "HN28_P15_D06_S330_comb     0.0000000       0.0000000       0.1216800     \n",
       "HN28_P6_G05_S173_comb      0.0000000       0.0000000       0.1953500     \n",
       "HN26_P14_D11_S239_comb     0.0000000       0.0000000       0.0214800     \n",
       "HN26_P14_H05_S281_comb     0.0000000       0.0000000       0.0894980     \n",
       "HN26_P25_H09_S189_comb     0.0000000       2.1385000       0.2289700     \n",
       "HN26_P14_H06_S282_comb     0.0000000       0.0000000       1.2016000     \n",
       "HN25_P25_C04_S316_comb     0.0000000       0.0000000       0.3628900     \n",
       "HN26_P25_A11_S107_comb     0.0000000       0.0000000       0.0976110     \n",
       "HN26_P25_C09_S129_comb     0.0000000       0.0000000       0.0621220     \n",
       "HNSCC26_P24_H05_S377_comb  0.0000000       0.0000000       0.6229300     \n",
       "HN25_P5_E10_S58_comb       0.000000        0.000000        0.028569      \n",
       "HN25_P24_B02_S110_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN25_P25_C01_S313_comb     0.0000000       0.0000000       0.1003000     \n",
       "HN28_P15_G06_S366_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN26_P6_B06_S18_comb       0.0000000       0.0000000       0.1230000     \n",
       "HN25_P5_C05_S29_comb       0.7311800       0.0000000       0.0662610     \n",
       "HN28_P6_D09_S141_comb      0.000000        0.000000        0.000000      \n",
       "HN26_P5_H01_S85_comb       0.0000000       0.0000000       0.1466600     \n",
       "HN26_P13_D07_S139_comb     0.0000000       0.0000000       0.0000000     \n",
       "HN26_P5_E06_S54_comb       1.9404000       1.3346000       0.0186340     \n",
       "HN26_P26_H05_S377_comb     0.0000000       0.0000000       0.0662610     \n",
       "HNSCC26_P24_F12_S360_comb  0.0000000       0.0000000       0.0538060     \n",
       "HNSCC26_P24_F03_S351_comb  0.0000000       0.0000000       0.0000000     \n",
       "HN26_P6_D08_S44_comb       0.0000000       0.0000000       0.0328060     \n",
       "HN25_P5_E12_S60_comb       0.0000000       0.0000000       0.1056800     \n",
       "HNSCC26_P24_C01_S313_comb  0.0000000       0.0000000       0.0243200     \n",
       "HN25_P5_F01_S61_comb       0.0000000       0.0000000       0.0648830     \n",
       "HN26_P5_D12_S48_comb       0.000000        0.000000        4.464900      \n",
       "HN25_P25_C11_S323_comb     0.0000000       0.0000000       0.0717630     \n",
       "HN25_P25_B12_S312_comb     0.0000000       0.0000000       0.0496310     \n",
       "⋮                         ⋮               ⋮               ⋮              \n",
       "HNSCC17_P4_A08_S104_comb   0.0000000       0.0000000       1.0072000     \n",
       "HNSCC17_P4_E10_S154_comb   0.0000000       0.0000000       0.0214800     \n",
       "HNSCC17_P4_E02_S146_comb   0.000000        0.000000        0.000000      \n",
       "HNSCC20_P13_F10_S262_comb  0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_D04_S136_comb   0.0000000       1.4782000       0.0229000     \n",
       "HNSCC20_P13_C06_S222_comb  0.0000000       0.0000000       0.2351100     \n",
       "HNSCC20_P13_C12_S228_comb  0.000000        0.000000        1.292200      \n",
       "HNSCC17_P4_H04_S184_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_C06_S126_comb   0.0000000       0.0000000       0.4520700     \n",
       "HNSCC20_P3_D01_S37_comb    0.1427400       0.0000000       0.4936500     \n",
       "HNSCC20_P3_D09_S45_comb    0.000000        0.000000        0.000000      \n",
       "HNSCC17_P4_E06_S150_comb   0.0000000       0.0000000       0.0157830     \n",
       "HNSCC20_P13_H10_S286_comb  0.0000000       0.0000000       0.0398400     \n",
       "HNSCC17_P4_A02_S98_comb    0.0000000       0.0000000       0.1414300     \n",
       "HNSCC20_P13_D01_S229_comb  0.0000000       0.0000000       0.0635030     \n",
       "HNSCC20_P13_G02_S266_comb  0.0827030       0.0000000       0.0662610     \n",
       "HNSCC17_P4_B04_S112_comb   0.0000000       0.0000000       1.9149000     \n",
       "HNSCC17_P4_C09_S129_comb   0.0000000       0.0000000       3.1090000     \n",
       "HNSCC20_P13_A12_S204_comb  0.0000000       0.0000000       0.0772430     \n",
       "HNSCC17_P4_F06_S162_comb   0.0000000       0.0000000       0.2448900     \n",
       "HNSCC20_P3_B10_S22_comb    0.0000000       0.7092900       1.4415000     \n",
       "HNSCC20_P13_B11_S215_comb  0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P3_C08_S32_comb    0.0000000       0.0000000       0.0412430     \n",
       "HNSCC17_P4_H03_S183_comb   0.0000000       0.0000000       0.0129260     \n",
       "HNSCC20_P3_F09_S69_comb    0.0000000       0.0000000       0.6069200     \n",
       "HNSCC17_P4_G12_S180_comb   0.0000000       0.0000000       4.1886000     \n",
       "HNSCC20_P13_C05_S221_comb  0.0000000       0.0000000       0.2473200     \n",
       "HNSCC17_P4_C12_S132_comb   0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P3_H08_S92_comb    0.0000000       0.0000000       0.1570400     \n",
       "HNSCC20_P3_G06_S78_comb    0.0000000       0.0000000       0.0342160     \n",
       "                          ENSG00000203995 ENSG00000162378 ENSG00000159840\n",
       "HN28_P15_D06_S330_comb     0.1635000       0.0908530       4.2748000     \n",
       "HN28_P6_G05_S173_comb      0.2797700       3.9348000       0.0000000     \n",
       "HN26_P14_D11_S239_comb     0.0000000       0.0731350       0.0000000     \n",
       "HN26_P14_H05_S281_comb     0.1865000       0.2141200       0.1243300     \n",
       "HN26_P25_H09_S189_comb     0.1335600       2.9059000       3.0034000     \n",
       "HN26_P14_H06_S282_comb     0.0635030       0.0510240       0.6050200     \n",
       "HN25_P25_C04_S316_comb     1.0881000       0.8559900       0.0000000     \n",
       "HN26_P25_A11_S107_comb     0.0676390       0.0000000       5.2928000     \n",
       "HN26_P25_C09_S129_comb     0.0328060       0.0922070       0.0000000     \n",
       "HNSCC26_P24_H05_S377_comb  0.2215700       0.4200800       0.5568000     \n",
       "HN25_P5_E10_S58_comb       0.332280        0.313830        3.916600      \n",
       "HN25_P24_B02_S110_comb     0.0000000       1.0468000       1.9381000     \n",
       "HN25_P25_C01_S313_comb     0.5916800       0.1890300       0.0000000     \n",
       "HN28_P15_G06_S366_comb     0.0000000       0.3584000       4.3710000     \n",
       "HN26_P6_B06_S18_comb       0.2215700       0.2545900       0.0000000     \n",
       "HN25_P5_C05_S29_comb       0.0000000       0.6397000       3.1760000     \n",
       "HN28_P6_D09_S141_comb      0.000000        0.458380        2.233300      \n",
       "HN26_P5_H01_S85_comb       0.1256500       2.1712000       0.0000000     \n",
       "HN26_P13_D07_S139_comb     0.1839600       0.1826900       6.7985000     \n",
       "HN26_P5_E06_S54_comb       0.1427400       0.0989580       2.6889000     \n",
       "HN26_P26_H05_S377_comb     0.0731350       0.0454430       0.0000000     \n",
       "HNSCC26_P24_F12_S360_comb  0.4179200       0.1256500       2.6383000     \n",
       "HNSCC26_P24_F03_S351_comb  0.0690150       0.1056800       0.0000000     \n",
       "HN26_P6_D08_S44_comb       0.1083600       0.1348800       1.5246000     \n",
       "HN25_P5_E12_S60_comb       0.0000000       0.0827030       3.8996000     \n",
       "HNSCC26_P24_C01_S313_comb  0.1375000       0.4782000       0.0000000     \n",
       "HN25_P5_F01_S61_comb       0.1596300       0.0000000       3.4525000     \n",
       "HN26_P5_D12_S48_comb       0.735520        0.626670        5.489100      \n",
       "HN25_P25_C11_S323_comb     0.1216800       0.1865000       0.0000000     \n",
       "HN25_P25_B12_S312_comb     0.0813400       1.2702000       2.3291000     \n",
       "⋮                         ⋮               ⋮               ⋮              \n",
       "HNSCC17_P4_A08_S104_comb   0.1401200       0.0635030       1.4114000     \n",
       "HNSCC17_P4_E10_S154_comb   0.0000000       0.0579700       1.7740000     \n",
       "HNSCC17_P4_E02_S146_comb   0.000000        0.591680        3.631600      \n",
       "HNSCC20_P13_F10_S262_comb  0.0000000       0.0000000       0.0000000     \n",
       "HNSCC17_P4_D04_S136_comb   0.0676390       0.0328060       4.0441000     \n",
       "HNSCC20_P13_C06_S222_comb  0.1826900       0.2314300       0.0000000     \n",
       "HNSCC20_P13_C12_S228_comb  0.000000        0.718960        2.784700      \n",
       "HNSCC17_P4_H04_S184_comb   0.0000000       0.0000000       0.6350600     \n",
       "HNSCC17_P4_C06_S126_comb   0.0000000       0.0000000       2.1130000     \n",
       "HNSCC20_P3_D01_S37_comb    0.0786100       0.0922070       3.2007000     \n",
       "HNSCC20_P3_D09_S45_comb    0.107020        0.000000        0.000000      \n",
       "HNSCC17_P4_E06_S150_comb   0.1322500       0.0000000       3.7401000     \n",
       "HNSCC20_P13_H10_S286_comb  1.0065000       0.0565840       0.0000000     \n",
       "HNSCC17_P4_A02_S98_comb    0.1479600       0.1492600       4.1065000     \n",
       "HNSCC20_P13_D01_S229_comb  0.0000000       0.0000000       0.0000000     \n",
       "HNSCC20_P13_G02_S266_comb  0.2461000       0.1096900       0.0000000     \n",
       "HNSCC17_P4_B04_S112_comb   0.0538060       0.1070200       0.9478500     \n",
       "HNSCC17_P4_C09_S129_comb   0.0551960       0.0662610       4.2718000     \n",
       "HNSCC20_P13_A12_S204_comb  0.0000000       0.0000000       0.1940900     \n",
       "HNSCC17_P4_F06_S162_comb   0.1163600       0.1177000       0.0000000     \n",
       "HNSCC20_P3_B10_S22_comb    0.0000000       0.7372500       3.3828000     \n",
       "HNSCC20_P13_B11_S215_comb  0.2016300       0.0000000       1.0007000     \n",
       "HNSCC20_P3_C08_S32_comb    0.0000000       0.0000000       2.5243000     \n",
       "HNSCC17_P4_H03_S183_comb   0.0000000       0.0370310       0.0000000     \n",
       "HNSCC20_P3_F09_S69_comb    0.0000000       0.0398400       0.6771700     \n",
       "HNSCC17_P4_G12_S180_comb   0.3983500       0.2545900       0.7527500     \n",
       "HNSCC20_P13_C05_S221_comb  0.7467400       0.3184600       0.0000000     \n",
       "HNSCC17_P4_C12_S132_comb   0.0000000       2.1063000       4.0557000     \n",
       "HNSCC20_P3_H08_S92_comb    0.2363400       0.2916000       3.7342000     \n",
       "HNSCC20_P3_G06_S78_comb    0.0000000       0.1110300       0.0000000     \n",
       "                          ENSG00000074755 ENSG00000036549\n",
       "HN28_P15_D06_S330_comb     0.0000000       0.0000000     \n",
       "HN28_P6_G05_S173_comb      3.7716000       0.0000000     \n",
       "HN26_P14_D11_S239_comb     1.3045000       2.1120000     \n",
       "HN26_P14_H05_S281_comb     0.0935600       0.0000000     \n",
       "HN26_P25_H09_S189_comb     0.0000000       0.0000000     \n",
       "HN26_P14_H06_S282_comb     0.0000000       0.0000000     \n",
       "HN25_P25_C04_S316_comb     0.8567900       0.0000000     \n",
       "HN26_P25_A11_S107_comb     0.0000000       0.0000000     \n",
       "HN26_P25_C09_S129_comb     0.0172090       0.0000000     \n",
       "HNSCC26_P24_H05_S377_comb  0.0000000       0.0000000     \n",
       "HN25_P5_E10_S58_comb       0.000000        0.000000      \n",
       "HN25_P24_B02_S110_comb     0.2363400       0.4467900     \n",
       "HN25_P25_C01_S313_comb     0.0000000       0.0000000     \n",
       "HN28_P15_G06_S366_comb     0.0000000       0.0000000     \n",
       "HN26_P6_B06_S18_comb       0.0000000       0.0000000     \n",
       "HN25_P5_C05_S29_comb       0.0000000       0.0000000     \n",
       "HN28_P6_D09_S141_comb      0.000000        0.000000      \n",
       "HN26_P5_H01_S85_comb       0.0000000       0.0000000     \n",
       "HN26_P13_D07_S139_comb     0.0000000       0.0000000     \n",
       "HN26_P5_E06_S54_comb       0.0000000       3.0526000     \n",
       "HN26_P26_H05_S377_comb     0.0172090       2.3923000     \n",
       "HNSCC26_P24_F12_S360_comb  0.0000000       0.0000000     \n",
       "HNSCC26_P24_F03_S351_comb  0.0000000       0.0000000     \n",
       "HN26_P6_D08_S44_comb       1.2029000       0.0000000     \n",
       "HN25_P5_E12_S60_comb       1.4885000       0.0000000     \n",
       "HNSCC26_P24_C01_S313_comb  1.3718000       1.9305000     \n",
       "HN25_P5_F01_S61_comb       0.0000000       0.0000000     \n",
       "HN26_P5_D12_S48_comb       0.000000        0.000000      \n",
       "HN25_P25_C11_S323_comb     0.2003800       0.0000000     \n",
       "HN25_P25_B12_S312_comb     1.3901000       0.0000000     \n",
       "⋮                         ⋮               ⋮              \n",
       "HNSCC17_P4_A08_S104_comb   0.0257380       1.3357000     \n",
       "HNSCC17_P4_E10_S154_comb   0.0000000       0.0000000     \n",
       "HNSCC17_P4_E02_S146_comb   0.000000        0.000000      \n",
       "HNSCC20_P13_F10_S262_comb  0.0000000       3.5203000     \n",
       "HNSCC17_P4_D04_S136_comb   0.5058900       0.0000000     \n",
       "HNSCC20_P13_C06_S222_comb  1.9381000       3.6758000     \n",
       "HNSCC20_P13_C12_S228_comb  0.000000        0.000000      \n",
       "HNSCC17_P4_H04_S184_comb   0.0000000       0.0000000     \n",
       "HNSCC17_P4_C06_S126_comb   0.0000000       0.5300700     \n",
       "HNSCC20_P3_D01_S37_comb    0.0000000       0.0000000     \n",
       "HNSCC20_P3_D09_S45_comb    0.000000        2.838800      \n",
       "HNSCC17_P4_E06_S150_comb   0.0000000       0.0000000     \n",
       "HNSCC20_P13_H10_S286_comb  0.0000000       3.6434000     \n",
       "HNSCC17_P4_A02_S98_comb    0.0000000       0.0000000     \n",
       "HNSCC20_P13_D01_S229_comb  1.4233000       0.0000000     \n",
       "HNSCC20_P13_G02_S266_comb  0.0000000       0.0000000     \n",
       "HNSCC17_P4_B04_S112_comb   0.0000000       0.0000000     \n",
       "HNSCC17_P4_C09_S129_comb   0.0000000       0.0000000     \n",
       "HNSCC20_P13_A12_S204_comb  1.1909000       1.1744000     \n",
       "HNSCC17_P4_F06_S162_comb   0.0000000       0.0000000     \n",
       "HNSCC20_P3_B10_S22_comb    0.1070200       2.2333000     \n",
       "HNSCC20_P13_B11_S215_comb  0.5753100       1.6808000     \n",
       "HNSCC20_P3_C08_S32_comb    0.1724900       0.0000000     \n",
       "HNSCC17_P4_H03_S183_comb   0.0000000       0.0000000     \n",
       "HNSCC20_P3_F09_S69_comb    1.0179000       0.0717630     \n",
       "HNSCC17_P4_G12_S180_comb   0.0000000       0.0000000     \n",
       "HNSCC20_P13_C05_S221_comb  0.0000000       0.0000000     \n",
       "HNSCC17_P4_C12_S132_comb   0.0000000       0.0000000     \n",
       "HNSCC20_P3_H08_S92_comb    0.0000000       0.0000000     \n",
       "HNSCC20_P3_G06_S78_comb    0.0000000       0.0000000     "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "df_Puram_t"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "id": "daaf2341",
   "metadata": {},
   "outputs": [],
   "source": []
  },
  {
   "cell_type": "code",
   "execution_count": 49,
   "id": "c8698c3e",
   "metadata": {},
   "outputs": [],
   "source": [
    "label <- read.table(\"./Puram/PuramHNSCC_cell_category_mappedCelltypes.csv\",sep=',',header=TRUE)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 12,
   "id": "334b7ee9",
   "metadata": {
    "scrolled": true
   },
   "outputs": [],
   "source": [
    "# celltypelab <- row.names(df_Puram_t)\n",
    "# head(celltypelab)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 50,
   "id": "59cdd26d",
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A data.frame: 5902 × 2</caption>\n",
       "<thead>\n",
       "\t<tr><th scope=col>X</th><th scope=col>cell_category</th></tr>\n",
       "\t<tr><th scope=col>&lt;chr&gt;</th><th scope=col>&lt;chr&gt;</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><td>HN28_P15_D06_S330_comb   </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN28_P6_G05_S173_comb    </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN26_P14_D11_S239_comb   </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN26_P14_H05_S281_comb   </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN26_P25_H09_S189_comb   </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN26_P14_H06_S282_comb   </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN25_P25_C04_S316_comb   </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN26_P25_A11_S107_comb   </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN26_P25_C09_S129_comb   </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HNSCC26_P24_H05_S377_comb</td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN25_P5_E10_S58_comb     </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN25_P24_B02_S110_comb   </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN25_P25_C01_S313_comb   </td><td>B cell    </td></tr>\n",
       "\t<tr><td>HN28_P15_G06_S366_comb   </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN26_P6_B06_S18_comb     </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN25_P5_C05_S29_comb     </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN28_P6_D09_S141_comb    </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN26_P5_H01_S85_comb     </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN26_P13_D07_S139_comb   </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN26_P5_E06_S54_comb     </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN26_P26_H05_S377_comb   </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HNSCC26_P24_F12_S360_comb</td><td>tumor     </td></tr>\n",
       "\t<tr><td>HNSCC26_P24_F03_S351_comb</td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN26_P6_D08_S44_comb     </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN25_P5_E12_S60_comb     </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HNSCC26_P24_C01_S313_comb</td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN25_P5_F01_S61_comb     </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN26_P5_D12_S48_comb     </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN25_P25_C11_S323_comb   </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN25_P25_B12_S312_comb   </td><td>tumor     </td></tr>\n",
       "\t<tr><td>⋮</td><td>⋮</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_A08_S104_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_E10_S154_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_E02_S146_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P13_F10_S262_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_D04_S136_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P13_C06_S222_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P13_C12_S228_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_H04_S184_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_C06_S126_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P3_D01_S37_comb  </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P3_D09_S45_comb  </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_E06_S150_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P13_H10_S286_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_A02_S98_comb  </td><td>NA   </td></tr>\n",
       "\t<tr><td>HNSCC20_P13_D01_S229_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P13_G02_S266_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_B04_S112_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_C09_S129_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P13_A12_S204_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_F06_S162_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P3_B10_S22_comb  </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P13_B11_S215_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P3_C08_S32_comb  </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_H03_S183_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P3_F09_S69_comb  </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_G12_S180_comb </td><td>NA   </td></tr>\n",
       "\t<tr><td>HNSCC20_P13_C05_S221_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_C12_S132_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P3_H08_S92_comb  </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P3_G06_S78_comb  </td><td>tumor</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A data.frame: 5902 × 2\n",
       "\\begin{tabular}{ll}\n",
       " X & cell\\_category\\\\\n",
       " <chr> & <chr>\\\\\n",
       "\\hline\n",
       "\t HN28\\_P15\\_D06\\_S330\\_comb    & Fibroblast\\\\\n",
       "\t HN28\\_P6\\_G05\\_S173\\_comb     & Fibroblast\\\\\n",
       "\t HN26\\_P14\\_D11\\_S239\\_comb    & tumor     \\\\\n",
       "\t HN26\\_P14\\_H05\\_S281\\_comb    & Fibroblast\\\\\n",
       "\t HN26\\_P25\\_H09\\_S189\\_comb    & tumor     \\\\\n",
       "\t HN26\\_P14\\_H06\\_S282\\_comb    & tumor     \\\\\n",
       "\t HN25\\_P25\\_C04\\_S316\\_comb    & tumor     \\\\\n",
       "\t HN26\\_P25\\_A11\\_S107\\_comb    & Fibroblast\\\\\n",
       "\t HN26\\_P25\\_C09\\_S129\\_comb    & tumor     \\\\\n",
       "\t HNSCC26\\_P24\\_H05\\_S377\\_comb & tumor     \\\\\n",
       "\t HN25\\_P5\\_E10\\_S58\\_comb      & Fibroblast\\\\\n",
       "\t HN25\\_P24\\_B02\\_S110\\_comb    & tumor     \\\\\n",
       "\t HN25\\_P25\\_C01\\_S313\\_comb    & B cell    \\\\\n",
       "\t HN28\\_P15\\_G06\\_S366\\_comb    & Fibroblast\\\\\n",
       "\t HN26\\_P6\\_B06\\_S18\\_comb      & Fibroblast\\\\\n",
       "\t HN25\\_P5\\_C05\\_S29\\_comb      & Fibroblast\\\\\n",
       "\t HN28\\_P6\\_D09\\_S141\\_comb     & Fibroblast\\\\\n",
       "\t HN26\\_P5\\_H01\\_S85\\_comb      & tumor     \\\\\n",
       "\t HN26\\_P13\\_D07\\_S139\\_comb    & Fibroblast\\\\\n",
       "\t HN26\\_P5\\_E06\\_S54\\_comb      & tumor     \\\\\n",
       "\t HN26\\_P26\\_H05\\_S377\\_comb    & tumor     \\\\\n",
       "\t HNSCC26\\_P24\\_F12\\_S360\\_comb & tumor     \\\\\n",
       "\t HNSCC26\\_P24\\_F03\\_S351\\_comb & tumor     \\\\\n",
       "\t HN26\\_P6\\_D08\\_S44\\_comb      & tumor     \\\\\n",
       "\t HN25\\_P5\\_E12\\_S60\\_comb      & Fibroblast\\\\\n",
       "\t HNSCC26\\_P24\\_C01\\_S313\\_comb & tumor     \\\\\n",
       "\t HN25\\_P5\\_F01\\_S61\\_comb      & Fibroblast\\\\\n",
       "\t HN26\\_P5\\_D12\\_S48\\_comb      & Fibroblast\\\\\n",
       "\t HN25\\_P25\\_C11\\_S323\\_comb    & Fibroblast\\\\\n",
       "\t HN25\\_P25\\_B12\\_S312\\_comb    & tumor     \\\\\n",
       "\t ⋮ & ⋮\\\\\n",
       "\t HNSCC17\\_P4\\_A08\\_S104\\_comb  & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_E10\\_S154\\_comb  & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_E02\\_S146\\_comb  & tumor\\\\\n",
       "\t HNSCC20\\_P13\\_F10\\_S262\\_comb & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_D04\\_S136\\_comb  & tumor\\\\\n",
       "\t HNSCC20\\_P13\\_C06\\_S222\\_comb & tumor\\\\\n",
       "\t HNSCC20\\_P13\\_C12\\_S228\\_comb & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_H04\\_S184\\_comb  & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_C06\\_S126\\_comb  & tumor\\\\\n",
       "\t HNSCC20\\_P3\\_D01\\_S37\\_comb   & tumor\\\\\n",
       "\t HNSCC20\\_P3\\_D09\\_S45\\_comb   & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_E06\\_S150\\_comb  & tumor\\\\\n",
       "\t HNSCC20\\_P13\\_H10\\_S286\\_comb & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_A02\\_S98\\_comb   & NA   \\\\\n",
       "\t HNSCC20\\_P13\\_D01\\_S229\\_comb & tumor\\\\\n",
       "\t HNSCC20\\_P13\\_G02\\_S266\\_comb & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_B04\\_S112\\_comb  & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_C09\\_S129\\_comb  & tumor\\\\\n",
       "\t HNSCC20\\_P13\\_A12\\_S204\\_comb & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_F06\\_S162\\_comb  & tumor\\\\\n",
       "\t HNSCC20\\_P3\\_B10\\_S22\\_comb   & tumor\\\\\n",
       "\t HNSCC20\\_P13\\_B11\\_S215\\_comb & tumor\\\\\n",
       "\t HNSCC20\\_P3\\_C08\\_S32\\_comb   & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_H03\\_S183\\_comb  & tumor\\\\\n",
       "\t HNSCC20\\_P3\\_F09\\_S69\\_comb   & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_G12\\_S180\\_comb  & NA   \\\\\n",
       "\t HNSCC20\\_P13\\_C05\\_S221\\_comb & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_C12\\_S132\\_comb  & tumor\\\\\n",
       "\t HNSCC20\\_P3\\_H08\\_S92\\_comb   & tumor\\\\\n",
       "\t HNSCC20\\_P3\\_G06\\_S78\\_comb   & tumor\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A data.frame: 5902 × 2\n",
       "\n",
       "| X &lt;chr&gt; | cell_category &lt;chr&gt; |\n",
       "|---|---|\n",
       "| HN28_P15_D06_S330_comb    | Fibroblast |\n",
       "| HN28_P6_G05_S173_comb     | Fibroblast |\n",
       "| HN26_P14_D11_S239_comb    | tumor      |\n",
       "| HN26_P14_H05_S281_comb    | Fibroblast |\n",
       "| HN26_P25_H09_S189_comb    | tumor      |\n",
       "| HN26_P14_H06_S282_comb    | tumor      |\n",
       "| HN25_P25_C04_S316_comb    | tumor      |\n",
       "| HN26_P25_A11_S107_comb    | Fibroblast |\n",
       "| HN26_P25_C09_S129_comb    | tumor      |\n",
       "| HNSCC26_P24_H05_S377_comb | tumor      |\n",
       "| HN25_P5_E10_S58_comb      | Fibroblast |\n",
       "| HN25_P24_B02_S110_comb    | tumor      |\n",
       "| HN25_P25_C01_S313_comb    | B cell     |\n",
       "| HN28_P15_G06_S366_comb    | Fibroblast |\n",
       "| HN26_P6_B06_S18_comb      | Fibroblast |\n",
       "| HN25_P5_C05_S29_comb      | Fibroblast |\n",
       "| HN28_P6_D09_S141_comb     | Fibroblast |\n",
       "| HN26_P5_H01_S85_comb      | tumor      |\n",
       "| HN26_P13_D07_S139_comb    | Fibroblast |\n",
       "| HN26_P5_E06_S54_comb      | tumor      |\n",
       "| HN26_P26_H05_S377_comb    | tumor      |\n",
       "| HNSCC26_P24_F12_S360_comb | tumor      |\n",
       "| HNSCC26_P24_F03_S351_comb | tumor      |\n",
       "| HN26_P6_D08_S44_comb      | tumor      |\n",
       "| HN25_P5_E12_S60_comb      | Fibroblast |\n",
       "| HNSCC26_P24_C01_S313_comb | tumor      |\n",
       "| HN25_P5_F01_S61_comb      | Fibroblast |\n",
       "| HN26_P5_D12_S48_comb      | Fibroblast |\n",
       "| HN25_P25_C11_S323_comb    | Fibroblast |\n",
       "| HN25_P25_B12_S312_comb    | tumor      |\n",
       "| ⋮ | ⋮ |\n",
       "| HNSCC17_P4_A08_S104_comb  | tumor |\n",
       "| HNSCC17_P4_E10_S154_comb  | tumor |\n",
       "| HNSCC17_P4_E02_S146_comb  | tumor |\n",
       "| HNSCC20_P13_F10_S262_comb | tumor |\n",
       "| HNSCC17_P4_D04_S136_comb  | tumor |\n",
       "| HNSCC20_P13_C06_S222_comb | tumor |\n",
       "| HNSCC20_P13_C12_S228_comb | tumor |\n",
       "| HNSCC17_P4_H04_S184_comb  | tumor |\n",
       "| HNSCC17_P4_C06_S126_comb  | tumor |\n",
       "| HNSCC20_P3_D01_S37_comb   | tumor |\n",
       "| HNSCC20_P3_D09_S45_comb   | tumor |\n",
       "| HNSCC17_P4_E06_S150_comb  | tumor |\n",
       "| HNSCC20_P13_H10_S286_comb | tumor |\n",
       "| HNSCC17_P4_A02_S98_comb   | NA    |\n",
       "| HNSCC20_P13_D01_S229_comb | tumor |\n",
       "| HNSCC20_P13_G02_S266_comb | tumor |\n",
       "| HNSCC17_P4_B04_S112_comb  | tumor |\n",
       "| HNSCC17_P4_C09_S129_comb  | tumor |\n",
       "| HNSCC20_P13_A12_S204_comb | tumor |\n",
       "| HNSCC17_P4_F06_S162_comb  | tumor |\n",
       "| HNSCC20_P3_B10_S22_comb   | tumor |\n",
       "| HNSCC20_P13_B11_S215_comb | tumor |\n",
       "| HNSCC20_P3_C08_S32_comb   | tumor |\n",
       "| HNSCC17_P4_H03_S183_comb  | tumor |\n",
       "| HNSCC20_P3_F09_S69_comb   | tumor |\n",
       "| HNSCC17_P4_G12_S180_comb  | NA    |\n",
       "| HNSCC20_P13_C05_S221_comb | tumor |\n",
       "| HNSCC17_P4_C12_S132_comb  | tumor |\n",
       "| HNSCC20_P3_H08_S92_comb   | tumor |\n",
       "| HNSCC20_P3_G06_S78_comb   | tumor |\n",
       "\n"
      ],
      "text/plain": [
       "     X                         cell_category\n",
       "1    HN28_P15_D06_S330_comb    Fibroblast   \n",
       "2    HN28_P6_G05_S173_comb     Fibroblast   \n",
       "3    HN26_P14_D11_S239_comb    tumor        \n",
       "4    HN26_P14_H05_S281_comb    Fibroblast   \n",
       "5    HN26_P25_H09_S189_comb    tumor        \n",
       "6    HN26_P14_H06_S282_comb    tumor        \n",
       "7    HN25_P25_C04_S316_comb    tumor        \n",
       "8    HN26_P25_A11_S107_comb    Fibroblast   \n",
       "9    HN26_P25_C09_S129_comb    tumor        \n",
       "10   HNSCC26_P24_H05_S377_comb tumor        \n",
       "11   HN25_P5_E10_S58_comb      Fibroblast   \n",
       "12   HN25_P24_B02_S110_comb    tumor        \n",
       "13   HN25_P25_C01_S313_comb    B cell       \n",
       "14   HN28_P15_G06_S366_comb    Fibroblast   \n",
       "15   HN26_P6_B06_S18_comb      Fibroblast   \n",
       "16   HN25_P5_C05_S29_comb      Fibroblast   \n",
       "17   HN28_P6_D09_S141_comb     Fibroblast   \n",
       "18   HN26_P5_H01_S85_comb      tumor        \n",
       "19   HN26_P13_D07_S139_comb    Fibroblast   \n",
       "20   HN26_P5_E06_S54_comb      tumor        \n",
       "21   HN26_P26_H05_S377_comb    tumor        \n",
       "22   HNSCC26_P24_F12_S360_comb tumor        \n",
       "23   HNSCC26_P24_F03_S351_comb tumor        \n",
       "24   HN26_P6_D08_S44_comb      tumor        \n",
       "25   HN25_P5_E12_S60_comb      Fibroblast   \n",
       "26   HNSCC26_P24_C01_S313_comb tumor        \n",
       "27   HN25_P5_F01_S61_comb      Fibroblast   \n",
       "28   HN26_P5_D12_S48_comb      Fibroblast   \n",
       "29   HN25_P25_C11_S323_comb    Fibroblast   \n",
       "30   HN25_P25_B12_S312_comb    tumor        \n",
       "⋮    ⋮                         ⋮            \n",
       "5873 HNSCC17_P4_A08_S104_comb  tumor        \n",
       "5874 HNSCC17_P4_E10_S154_comb  tumor        \n",
       "5875 HNSCC17_P4_E02_S146_comb  tumor        \n",
       "5876 HNSCC20_P13_F10_S262_comb tumor        \n",
       "5877 HNSCC17_P4_D04_S136_comb  tumor        \n",
       "5878 HNSCC20_P13_C06_S222_comb tumor        \n",
       "5879 HNSCC20_P13_C12_S228_comb tumor        \n",
       "5880 HNSCC17_P4_H04_S184_comb  tumor        \n",
       "5881 HNSCC17_P4_C06_S126_comb  tumor        \n",
       "5882 HNSCC20_P3_D01_S37_comb   tumor        \n",
       "5883 HNSCC20_P3_D09_S45_comb   tumor        \n",
       "5884 HNSCC17_P4_E06_S150_comb  tumor        \n",
       "5885 HNSCC20_P13_H10_S286_comb tumor        \n",
       "5886 HNSCC17_P4_A02_S98_comb   NA           \n",
       "5887 HNSCC20_P13_D01_S229_comb tumor        \n",
       "5888 HNSCC20_P13_G02_S266_comb tumor        \n",
       "5889 HNSCC17_P4_B04_S112_comb  tumor        \n",
       "5890 HNSCC17_P4_C09_S129_comb  tumor        \n",
       "5891 HNSCC20_P13_A12_S204_comb tumor        \n",
       "5892 HNSCC17_P4_F06_S162_comb  tumor        \n",
       "5893 HNSCC20_P3_B10_S22_comb   tumor        \n",
       "5894 HNSCC20_P13_B11_S215_comb tumor        \n",
       "5895 HNSCC20_P3_C08_S32_comb   tumor        \n",
       "5896 HNSCC17_P4_H03_S183_comb  tumor        \n",
       "5897 HNSCC20_P3_F09_S69_comb   tumor        \n",
       "5898 HNSCC17_P4_G12_S180_comb  NA           \n",
       "5899 HNSCC20_P13_C05_S221_comb tumor        \n",
       "5900 HNSCC17_P4_C12_S132_comb  tumor        \n",
       "5901 HNSCC20_P3_H08_S92_comb   tumor        \n",
       "5902 HNSCC20_P3_G06_S78_comb   tumor        "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "label"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 13,
   "id": "e808e504",
   "metadata": {},
   "outputs": [],
   "source": [
    "# fixing the problem summing characters in df\n",
    "class(df_Puram_t)<-'numeric'"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 14,
   "id": "09d231fd",
   "metadata": {},
   "outputs": [],
   "source": [
    "class(df_TCGA_t)<-'numeric'"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 15,
   "id": "15169155",
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<style>\n",
       ".list-inline {list-style: none; margin:0; padding: 0}\n",
       ".list-inline>li {display: inline-block}\n",
       ".list-inline>li:not(:last-child)::after {content: \"\\00b7\"; padding: 0 .5ex}\n",
       "</style>\n",
       "<ol class=list-inline><li>'matrix'</li><li>'array'</li></ol>\n"
      ],
      "text/latex": [
       "\\begin{enumerate*}\n",
       "\\item 'matrix'\n",
       "\\item 'array'\n",
       "\\end{enumerate*}\n"
      ],
      "text/markdown": [
       "1. 'matrix'\n",
       "2. 'array'\n",
       "\n",
       "\n"
      ],
      "text/plain": [
       "[1] \"matrix\" \"array\" "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "# class(df_Puram_t)"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "f75bbc62",
   "metadata": {},
   "source": [
    "#### Run cleanup procedure, to remove \"RB\"=ribosomal genes; \"chrM\"=mitochondrial genes; \"chrX\" and \"chrY\" denoting genes on the sex chromosome.\n",
    "- 18332 genes left, \n",
    "- 5902 single cells, 547 bulk samples\n",
    "- 9 celltypes (all tumors are same), 1 NA type"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 17,
   "id": "3ae160e4",
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "[1] \"EMSEMBLE IDs detected. Cleaning up genes based on EMSEMBLE IDs.\"\n",
      "A total of  1226  genes from RB chrM chrX chrY  have been excluded \n",
      "A total of  2255  lowly expressed genes have been excluded \n"
     ]
    }
   ],
   "source": [
    "ref.data.filtered <- cleanup.genes(ref.dat=df_Puram_t, gene.type=c(\"RB\",\"chrM\",\"chrX\",\"chrY\"), species=\"hs\", input.type=\"scRNA\",exp.cells=5)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 37,
   "id": "46553142",
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A matrix: 5902 × 18332 of type dbl</caption>\n",
       "<thead>\n",
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       "</thead>\n",
       "<tbody>\n",
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       "\t<tr><th scope=row>HN28_P6_G05_S173_comb</th><td>0.000000</td><td>0.0000</td><td>0.00000</td><td>7.583000</td><td>0.00000</td><td>0.000000</td><td>0</td><td>0.00000</td><td>0</td><td>4.6920</td><td>⋯</td><td>0.000000</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>0.195350</td><td>0.279770</td><td>3.934800</td><td>0.00000</td><td>3.771600</td><td>0.00000</td></tr>\n",
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       "\t<tr><th scope=row>HN26_P25_H09_S189_comb</th><td>0.000000</td><td>0.0000</td><td>0.00000</td><td>0.000000</td><td>0.00000</td><td>0.000000</td><td>0</td><td>0.00000</td><td>0</td><td>4.7785</td><td>⋯</td><td>0.000000</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>0.228970</td><td>0.133560</td><td>2.905900</td><td>3.00340</td><td>0.000000</td><td>0.00000</td></tr>\n",
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       "\t<tr><th scope=row>HN25_P25_C04_S316_comb</th><td>0.000000</td><td>0.0000</td><td>0.00000</td><td>0.196610</td><td>0.00000</td><td>0.000000</td><td>0</td><td>0.00000</td><td>0</td><td>5.3764</td><td>⋯</td><td>4.397100</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>0.362890</td><td>1.088100</td><td>0.855990</td><td>0.00000</td><td>0.856790</td><td>0.00000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P25_A11_S107_comb</th><td>0.541020</td><td>0.0000</td><td>0.00000</td><td>7.706000</td><td>0.00000</td><td>0.000000</td><td>0</td><td>0.00000</td><td>0</td><td>4.1304</td><td>⋯</td><td>0.000000</td><td>4.216400</td><td>4.63480</td><td>0.0000</td><td>0.097611</td><td>0.067639</td><td>0.000000</td><td>5.29280</td><td>0.000000</td><td>0.00000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P25_C09_S129_comb</th><td>0.000000</td><td>0.0000</td><td>0.00000</td><td>0.000000</td><td>0.00000</td><td>1.125000</td><td>0</td><td>0.00000</td><td>0</td><td>0.0000</td><td>⋯</td><td>4.787500</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>0.062122</td><td>0.032806</td><td>0.092207</td><td>0.00000</td><td>0.017209</td><td>0.00000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_H05_S377_comb</th><td>1.300400</td><td>0.0000</td><td>0.00000</td><td>0.000000</td><td>2.61920</td><td>0.125650</td><td>0</td><td>0.00000</td><td>0</td><td>0.0000</td><td>⋯</td><td>0.000000</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>0.622930</td><td>0.221570</td><td>0.420080</td><td>0.55680</td><td>0.000000</td><td>0.00000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_E10_S58_comb</th><td>1.983300</td><td>0.0000</td><td>0.00000</td><td>7.285600</td><td>0.00000</td><td>0.000000</td><td>0</td><td>4.44510</td><td>0</td><td>0.0000</td><td>⋯</td><td>0.000000</td><td>4.317400</td><td>0.00000</td><td>0.0000</td><td>0.028569</td><td>0.332280</td><td>0.313830</td><td>3.91660</td><td>0.000000</td><td>0.00000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P24_B02_S110_comb</th><td>0.000000</td><td>0.0000</td><td>0.00000</td><td>0.000000</td><td>0.00000</td><td>1.950500</td><td>0</td><td>0.00000</td><td>0</td><td>3.0177</td><td>⋯</td><td>1.237600</td><td>2.535600</td><td>0.00000</td><td>3.7281</td><td>0.000000</td><td>0.000000</td><td>1.046800</td><td>1.93810</td><td>0.236340</td><td>0.44679</td></tr>\n",
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       "\t<tr><th scope=row>HN25_P5_F01_S61_comb</th><td>0.000000</td><td>0.0000</td><td>0.00000</td><td>9.708900</td><td>0.00000</td><td>0.173770</td><td>0</td><td>0.00000</td><td>0</td><td>0.0000</td><td>⋯</td><td>0.000000</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>0.064883</td><td>0.159630</td><td>0.000000</td><td>3.45250</td><td>0.000000</td><td>0.00000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P5_D12_S48_comb</th><td>0.000000</td><td>0.0000</td><td>0.00000</td><td>8.795600</td><td>0.00000</td><td>0.000000</td><td>0</td><td>0.00000</td><td>0</td><td>0.0000</td><td>⋯</td><td>0.000000</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>4.464900</td><td>0.735520</td><td>0.626670</td><td>5.48910</td><td>0.000000</td><td>0.00000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_C11_S323_comb</th><td>0.000000</td><td>0.0000</td><td>0.02148</td><td>4.939200</td><td>0.00000</td><td>0.000000</td><td>0</td><td>0.00000</td><td>0</td><td>4.7985</td><td>⋯</td><td>0.000000</td><td>0.000000</td><td>4.17720</td><td>0.0000</td><td>0.071763</td><td>0.121680</td><td>0.186500</td><td>0.00000</td><td>0.200380</td><td>0.00000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_B12_S312_comb</th><td>0.000000</td><td>0.0000</td><td>0.00000</td><td>0.000000</td><td>0.00000</td><td>0.037031</td><td>0</td><td>0.00000</td><td>0</td><td>4.7680</td><td>⋯</td><td>0.064883</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>0.049631</td><td>0.081340</td><td>1.270200</td><td>2.32910</td><td>1.390100</td><td>0.00000</td></tr>\n",
       "\t<tr><th scope=row>⋮</th><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋱</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_A08_S104_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>0.00000</td><td>0</td><td>2.58470</td><td>⋯</td><td>0.00000</td><td>0.000000</td><td>1.03490</td><td>4.1908</td><td>1.007200</td><td>0.140120</td><td>0.063503</td><td>1.41140</td><td>0.025738</td><td>1.335700</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E10_S154_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>0.00000</td><td>0</td><td>4.23760</td><td>⋯</td><td>0.00000</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>0.021480</td><td>0.000000</td><td>0.057970</td><td>1.77400</td><td>0.000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E02_S146_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>3.012700</td><td>0</td><td>0.00000</td><td>0</td><td>0.00000</td><td>⋯</td><td>0.00000</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0.000000</td><td>0.591680</td><td>3.63160</td><td>0.000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_F10_S262_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>4.84390</td><td>0</td><td>4.82620</td><td>⋯</td><td>0.00000</td><td>0.331130</td><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0.000000</td><td>0.000000</td><td>0.00000</td><td>0.000000</td><td>3.520300</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_D04_S136_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.063503</td><td>0</td><td>0.43403</td><td>0</td><td>0.28214</td><td>⋯</td><td>0.00000</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>0.022900</td><td>0.067639</td><td>0.032806</td><td>4.04410</td><td>0.505890</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C06_S222_comb</th><td>0.00000</td><td>0.0000</td><td>0.046840</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>5.43390</td><td>0</td><td>0.00000</td><td>⋯</td><td>1.68210</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>0.235110</td><td>0.182690</td><td>0.231430</td><td>0.00000</td><td>1.938100</td><td>3.675800</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C12_S228_comb</th><td>1.11240</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>2.33490</td><td>0</td><td>3.09170</td><td>⋯</td><td>0.00000</td><td>3.823400</td><td>0.00000</td><td>0.0000</td><td>1.292200</td><td>0.000000</td><td>0.718960</td><td>2.78470</td><td>0.000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_H04_S184_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>1.22090</td><td>0</td><td>3.91210</td><td>⋯</td><td>0.00000</td><td>3.586600</td><td>0.54300</td><td>0.0000</td><td>0.000000</td><td>0.000000</td><td>0.000000</td><td>0.63506</td><td>0.000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C06_S126_comb</th><td>0.99132</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>1.24370</td><td>0</td><td>0.00000</td><td>⋯</td><td>0.00000</td><td>0.000000</td><td>2.28950</td><td>0.0000</td><td>0.452070</td><td>0.000000</td><td>0.000000</td><td>2.11300</td><td>0.000000</td><td>0.530070</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_D01_S37_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>4.28630</td><td>0</td><td>3.29500</td><td>⋯</td><td>0.00000</td><td>3.167700</td><td>0.00000</td><td>4.3682</td><td>0.493650</td><td>0.078610</td><td>0.092207</td><td>3.20070</td><td>0.000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_D09_S45_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.096262</td><td>0</td><td>4.38340</td><td>0</td><td>0.00000</td><td>⋯</td><td>0.00000</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0.107020</td><td>0.000000</td><td>0.00000</td><td>0.000000</td><td>2.838800</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E06_S150_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.574340</td><td>0</td><td>0.00000</td><td>0</td><td>0.00000</td><td>⋯</td><td>2.89380</td><td>2.428700</td><td>0.00000</td><td>0.0000</td><td>0.015783</td><td>0.132250</td><td>0.000000</td><td>3.74010</td><td>0.000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_H10_S286_comb</th><td>0.00000</td><td>0.0000</td><td>0.048236</td><td>0</td><td>0</td><td>3.034200</td><td>0</td><td>4.05260</td><td>0</td><td>3.51260</td><td>⋯</td><td>2.55780</td><td>2.573600</td><td>3.39900</td><td>5.6353</td><td>0.039840</td><td>1.006500</td><td>0.056584</td><td>0.00000</td><td>0.000000</td><td>3.643400</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_A02_S98_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.138810</td><td>0</td><td>0.00000</td><td>0</td><td>0.00000</td><td>⋯</td><td>0.00000</td><td>0.090853</td><td>0.00000</td><td>0.0000</td><td>0.141430</td><td>0.147960</td><td>0.149260</td><td>4.10650</td><td>0.000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_D01_S229_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>5.22440</td><td>0</td><td>0.00000</td><td>⋯</td><td>0.00000</td><td>3.206500</td><td>3.06590</td><td>0.0000</td><td>0.063503</td><td>0.000000</td><td>0.000000</td><td>0.00000</td><td>1.423300</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_G02_S266_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>4.14670</td><td>0</td><td>1.15960</td><td>⋯</td><td>0.00000</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>0.066261</td><td>0.246100</td><td>0.109690</td><td>0.00000</td><td>0.000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_B04_S112_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>0.00000</td><td>0</td><td>3.43500</td><td>⋯</td><td>0.00000</td><td>0.000000</td><td>3.57950</td><td>4.5380</td><td>1.914900</td><td>0.053806</td><td>0.107020</td><td>0.94785</td><td>0.000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C09_S129_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>2.56540</td><td>0</td><td>0.00000</td><td>⋯</td><td>0.00000</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>3.109000</td><td>0.055196</td><td>0.066261</td><td>4.27180</td><td>0.000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_A12_S204_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>5.308300</td><td>0</td><td>3.65020</td><td>0</td><td>0.00000</td><td>⋯</td><td>0.00000</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>0.077243</td><td>0.000000</td><td>0.000000</td><td>0.19409</td><td>1.190900</td><td>1.174400</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_F06_S162_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>0.00000</td><td>0</td><td>0.00000</td><td>⋯</td><td>0.00000</td><td>0.000000</td><td>0.00000</td><td>4.6224</td><td>0.244890</td><td>0.116360</td><td>0.117700</td><td>0.00000</td><td>0.000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_B10_S22_comb</th><td>0.63320</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.311500</td><td>0</td><td>5.18090</td><td>0</td><td>0.00000</td><td>⋯</td><td>1.00070</td><td>2.346200</td><td>1.55140</td><td>3.0491</td><td>1.441500</td><td>0.000000</td><td>0.737250</td><td>3.38280</td><td>0.107020</td><td>2.233300</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_B11_S215_comb</th><td>1.22590</td><td>1.0642</td><td>0.000000</td><td>0</td><td>0</td><td>5.735100</td><td>0</td><td>3.65520</td><td>0</td><td>2.04050</td><td>⋯</td><td>0.00000</td><td>2.066300</td><td>2.88520</td><td>4.5492</td><td>0.000000</td><td>0.201630</td><td>0.000000</td><td>1.00070</td><td>0.575310</td><td>1.680800</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_C08_S32_comb</th><td>1.37740</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>5.05750</td><td>0</td><td>3.31510</td><td>⋯</td><td>0.00000</td><td>0.000000</td><td>2.12200</td><td>0.0000</td><td>0.041243</td><td>0.000000</td><td>0.000000</td><td>2.52430</td><td>0.172490</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_H03_S183_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>0.00000</td><td>0</td><td>4.38080</td><td>⋯</td><td>0.00000</td><td>4.277300</td><td>0.00000</td><td>4.5356</td><td>0.012926</td><td>0.000000</td><td>0.037031</td><td>0.00000</td><td>0.000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_F09_S69_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>2.68890</td><td>0</td><td>0.00000</td><td>⋯</td><td>0.00000</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>0.606920</td><td>0.000000</td><td>0.039840</td><td>0.67717</td><td>1.017900</td><td>0.071763</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_G12_S180_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>0.00000</td><td>0</td><td>0.00000</td><td>⋯</td><td>2.25850</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>4.188600</td><td>0.398350</td><td>0.254590</td><td>0.75275</td><td>0.000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C05_S221_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>5.08770</td><td>0</td><td>0.00000</td><td>⋯</td><td>0.48954</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>0.247320</td><td>0.746740</td><td>0.318460</td><td>0.00000</td><td>0.000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C12_S132_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.042644</td><td>0</td><td>1.81110</td><td>0</td><td>3.65280</td><td>⋯</td><td>0.00000</td><td>3.737300</td><td>0.10165</td><td>3.4737</td><td>0.000000</td><td>0.000000</td><td>2.106300</td><td>4.05570</td><td>0.000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_H08_S92_comb</th><td>2.99960</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>0.000000</td><td>0</td><td>3.83700</td><td>0</td><td>4.07110</td><td>⋯</td><td>3.78200</td><td>0.000000</td><td>3.59690</td><td>0.0000</td><td>0.157040</td><td>0.236340</td><td>0.291600</td><td>3.73420</td><td>0.000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_G06_S78_comb</th><td>0.00000</td><td>0.0000</td><td>0.000000</td><td>0</td><td>0</td><td>3.406000</td><td>0</td><td>4.34800</td><td>0</td><td>0.00000</td><td>⋯</td><td>0.00000</td><td>0.000000</td><td>0.00000</td><td>0.0000</td><td>0.034216</td><td>0.000000</td><td>0.111030</td><td>0.00000</td><td>0.000000</td><td>0.000000</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A matrix: 5902 × 18332 of type dbl\n",
       "\\begin{tabular}{r|lllllllllllllllllllll}\n",
       "  & ENSG00000121410 & ENSG00000268895 & ENSG00000148584 & ENSG00000175899 & ENSG00000245105 & ENSG00000166535 & ENSG00000256069 & ENSG00000128274 & ENSG00000118017 & ENSG00000094914 & ⋯ & ENSG00000153975 & ENSG00000086827 & ENSG00000174442 & ENSG00000122952 & ENSG00000070476 & ENSG00000203995 & ENSG00000162378 & ENSG00000159840 & ENSG00000074755 & ENSG00000036549\\\\\n",
       "\\hline\n",
       "\tHN28\\_P15\\_D06\\_S330\\_comb & 0.000000 & 0.0000 & 0.00000 & 9.683000 & 0.17632 & 0.000000 & 0 & 2.24880 & 0 & 4.5423 & ⋯ & 0.000000 & 0.000000 & 0.00000 & 0.0000 & 0.121680 & 0.163500 & 0.090853 & 4.27480 & 0.000000 & 0.00000\\\\\n",
       "\tHN28\\_P6\\_G05\\_S173\\_comb & 0.000000 & 0.0000 & 0.00000 & 7.583000 & 0.00000 & 0.000000 & 0 & 0.00000 & 0 & 4.6920 & ⋯ & 0.000000 & 0.000000 & 0.00000 & 0.0000 & 0.195350 & 0.279770 & 3.934800 & 0.00000 & 3.771600 & 0.00000\\\\\n",
       "\tHN26\\_P14\\_D11\\_S239\\_comb & 0.000000 & 0.0000 & 0.00000 & 0.029983 & 0.00000 & 4.798800 & 0 & 0.00000 & 0 & 0.0000 & ⋯ & 4.172500 & 0.000000 & 0.00000 & 0.0000 & 0.021480 & 0.000000 & 0.073135 & 0.00000 & 1.304500 & 2.11200\\\\\n",
       "\tHN26\\_P14\\_H05\\_S281\\_comb & 0.000000 & 0.0000 & 0.00000 & 6.054700 & 0.00000 & 0.000000 & 0 & 0.26424 & 0 & 0.0000 & ⋯ & 0.000000 & 0.000000 & 0.00000 & 0.0000 & 0.089498 & 0.186500 & 0.214120 & 0.12433 & 0.093560 & 0.00000\\\\\n",
       "\tHN26\\_P25\\_H09\\_S189\\_comb & 0.000000 & 0.0000 & 0.00000 & 0.000000 & 0.00000 & 0.000000 & 0 & 0.00000 & 0 & 4.7785 & ⋯ & 0.000000 & 0.000000 & 0.00000 & 0.0000 & 0.228970 & 0.133560 & 2.905900 & 3.00340 & 0.000000 & 0.00000\\\\\n",
       "\tHN26\\_P14\\_H06\\_S282\\_comb & 0.066261 & 0.0000 & 0.00000 & 0.000000 & 0.00000 & 2.283000 & 0 & 0.00000 & 0 & 3.1225 & ⋯ & 0.000000 & 2.017200 & 0.87184 & 0.0000 & 1.201600 & 0.063503 & 0.051024 & 0.60502 & 0.000000 & 0.00000\\\\\n",
       "\tHN25\\_P25\\_C04\\_S316\\_comb & 0.000000 & 0.0000 & 0.00000 & 0.196610 & 0.00000 & 0.000000 & 0 & 0.00000 & 0 & 5.3764 & ⋯ & 4.397100 & 0.000000 & 0.00000 & 0.0000 & 0.362890 & 1.088100 & 0.855990 & 0.00000 & 0.856790 & 0.00000\\\\\n",
       "\tHN26\\_P25\\_A11\\_S107\\_comb & 0.541020 & 0.0000 & 0.00000 & 7.706000 & 0.00000 & 0.000000 & 0 & 0.00000 & 0 & 4.1304 & ⋯ & 0.000000 & 4.216400 & 4.63480 & 0.0000 & 0.097611 & 0.067639 & 0.000000 & 5.29280 & 0.000000 & 0.00000\\\\\n",
       "\tHN26\\_P25\\_C09\\_S129\\_comb & 0.000000 & 0.0000 & 0.00000 & 0.000000 & 0.00000 & 1.125000 & 0 & 0.00000 & 0 & 0.0000 & ⋯ & 4.787500 & 0.000000 & 0.00000 & 0.0000 & 0.062122 & 0.032806 & 0.092207 & 0.00000 & 0.017209 & 0.00000\\\\\n",
       "\tHNSCC26\\_P24\\_H05\\_S377\\_comb & 1.300400 & 0.0000 & 0.00000 & 0.000000 & 2.61920 & 0.125650 & 0 & 0.00000 & 0 & 0.0000 & ⋯ & 0.000000 & 0.000000 & 0.00000 & 0.0000 & 0.622930 & 0.221570 & 0.420080 & 0.55680 & 0.000000 & 0.00000\\\\\n",
       "\tHN25\\_P5\\_E10\\_S58\\_comb & 1.983300 & 0.0000 & 0.00000 & 7.285600 & 0.00000 & 0.000000 & 0 & 4.44510 & 0 & 0.0000 & ⋯ & 0.000000 & 4.317400 & 0.00000 & 0.0000 & 0.028569 & 0.332280 & 0.313830 & 3.91660 & 0.000000 & 0.00000\\\\\n",
       "\tHN25\\_P24\\_B02\\_S110\\_comb & 0.000000 & 0.0000 & 0.00000 & 0.000000 & 0.00000 & 1.950500 & 0 & 0.00000 & 0 & 3.0177 & ⋯ & 1.237600 & 2.535600 & 0.00000 & 3.7281 & 0.000000 & 0.000000 & 1.046800 & 1.93810 & 0.236340 & 0.44679\\\\\n",
       "\tHN25\\_P25\\_C01\\_S313\\_comb & 0.000000 & 0.0000 & 0.00000 & 0.000000 & 0.00000 & 0.000000 & 0 & 0.00000 & 0 & 0.0000 & ⋯ & 0.000000 & 0.000000 & 0.00000 & 0.0000 & 0.100300 & 0.591680 & 0.189030 & 0.00000 & 0.000000 & 0.00000\\\\\n",
       "\tHN28\\_P15\\_G06\\_S366\\_comb & 0.000000 & 0.0000 & 0.00000 & 7.852500 & 0.00000 & 0.000000 & 0 & 0.00000 & 0 & 5.7214 & ⋯ & 0.000000 & 0.000000 & 0.00000 & 4.3319 & 0.000000 & 0.000000 & 0.358400 & 4.37100 & 0.000000 & 0.00000\\\\\n",
       "\tHN26\\_P6\\_B06\\_S18\\_comb & 0.000000 & 0.0000 & 0.00000 & 8.313600 & 0.00000 & 0.000000 & 0 & 0.00000 & 0 & 0.0000 & ⋯ & 0.000000 & 0.000000 & 7.03750 & 0.0000 & 0.123000 & 0.221570 & 0.254590 & 0.00000 & 0.000000 & 0.00000\\\\\n",
       "\tHN25\\_P5\\_C05\\_S29\\_comb & 0.000000 & 0.0000 & 0.00000 & 0.049631 & 0.00000 & 0.000000 & 0 & 2.14960 & 0 & 0.0000 & ⋯ & 0.000000 & 0.079975 & 0.00000 & 0.0000 & 0.066261 & 0.000000 & 0.639700 & 3.17600 & 0.000000 & 0.00000\\\\\n",
       "\tHN28\\_P6\\_D09\\_S141\\_comb & 0.000000 & 0.0000 & 0.00000 & 0.000000 & 0.00000 & 0.000000 & 0 & 0.00000 & 0 & 0.0000 & ⋯ & 0.000000 & 0.000000 & 0.00000 & 0.0000 & 0.000000 & 0.000000 & 0.458380 & 2.23330 & 0.000000 & 0.00000\\\\\n",
       "\tHN26\\_P5\\_H01\\_S85\\_comb & 0.000000 & 0.0000 & 0.00000 & 0.000000 & 0.00000 & 4.807000 & 0 & 2.04540 & 0 & 4.4487 & ⋯ & 0.000000 & 0.000000 & 0.00000 & 0.0000 & 0.146660 & 0.125650 & 2.171200 & 0.00000 & 0.000000 & 0.00000\\\\\n",
       "\tHN26\\_P13\\_D07\\_S139\\_comb & 0.000000 & 0.0000 & 0.00000 & 8.063000 & 0.00000 & 0.000000 & 0 & 0.00000 & 0 & 0.0000 & ⋯ & 0.000000 & 0.000000 & 0.00000 & 0.0000 & 0.000000 & 0.183960 & 0.182690 & 6.79850 & 0.000000 & 0.00000\\\\\n",
       "\tHN26\\_P5\\_E06\\_S54\\_comb & 0.000000 & 0.0000 & 0.00000 & 0.000000 & 0.00000 & 0.000000 & 0 & 1.24370 & 0 & 4.2672 & ⋯ & 0.000000 & 0.000000 & 0.00000 & 0.0000 & 0.018634 & 0.142740 & 0.098958 & 2.68890 & 0.000000 & 3.05260\\\\\n",
       "\tHN26\\_P26\\_H05\\_S377\\_comb & 0.000000 & 0.0000 & 0.00000 & 0.000000 & 0.00000 & 1.495700 & 0 & 0.00000 & 0 & 0.0000 & ⋯ & 0.000000 & 0.000000 & 0.00000 & 0.0000 & 0.066261 & 0.073135 & 0.045443 & 0.00000 & 0.017209 & 2.39230\\\\\n",
       "\tHNSCC26\\_P24\\_F12\\_S360\\_comb & 0.000000 & 0.0000 & 0.00000 & 0.000000 & 0.00000 & 0.000000 & 0 & 0.00000 & 0 & 3.9039 & ⋯ & 0.000000 & 0.000000 & 0.00000 & 0.0000 & 0.053806 & 0.417920 & 0.125650 & 2.63830 & 0.000000 & 0.00000\\\\\n",
       "\tHNSCC26\\_P24\\_F03\\_S351\\_comb & 0.000000 & 0.0000 & 0.00000 & 0.000000 & 0.00000 & 0.000000 & 0 & 2.30680 & 0 & 0.0000 & ⋯ & 0.000000 & 0.000000 & 0.00000 & 0.0000 & 0.000000 & 0.069015 & 0.105680 & 0.00000 & 0.000000 & 0.00000\\\\\n",
       "\tHN26\\_P6\\_D08\\_S44\\_comb & 0.000000 & 0.0000 & 0.00000 & 0.000000 & 0.00000 & 5.313100 & 0 & 0.00000 & 0 & 0.0000 & ⋯ & 0.000000 & 2.457100 & 0.00000 & 0.0000 & 0.032806 & 0.108360 & 0.134880 & 1.52460 & 1.202900 & 0.00000\\\\\n",
       "\tHN25\\_P5\\_E12\\_S60\\_comb & 0.000000 & 2.0635 & 0.00000 & 9.080900 & 0.00000 & 0.000000 & 0 & 0.58496 & 0 & 0.0000 & ⋯ & 0.000000 & 4.536200 & 0.00000 & 0.0000 & 0.105680 & 0.000000 & 0.082703 & 3.89960 & 1.488500 & 0.00000\\\\\n",
       "\tHNSCC26\\_P24\\_C01\\_S313\\_comb & 0.000000 & 0.0000 & 0.00000 & 0.000000 & 0.00000 & 2.468100 & 0 & 0.00000 & 0 & 0.0000 & ⋯ & 0.000000 & 3.812700 & 0.00000 & 3.1533 & 0.024320 & 0.137500 & 0.478200 & 0.00000 & 1.371800 & 1.93050\\\\\n",
       "\tHN25\\_P5\\_F01\\_S61\\_comb & 0.000000 & 0.0000 & 0.00000 & 9.708900 & 0.00000 & 0.173770 & 0 & 0.00000 & 0 & 0.0000 & ⋯ & 0.000000 & 0.000000 & 0.00000 & 0.0000 & 0.064883 & 0.159630 & 0.000000 & 3.45250 & 0.000000 & 0.00000\\\\\n",
       "\tHN26\\_P5\\_D12\\_S48\\_comb & 0.000000 & 0.0000 & 0.00000 & 8.795600 & 0.00000 & 0.000000 & 0 & 0.00000 & 0 & 0.0000 & ⋯ & 0.000000 & 0.000000 & 0.00000 & 0.0000 & 4.464900 & 0.735520 & 0.626670 & 5.48910 & 0.000000 & 0.00000\\\\\n",
       "\tHN25\\_P25\\_C11\\_S323\\_comb & 0.000000 & 0.0000 & 0.02148 & 4.939200 & 0.00000 & 0.000000 & 0 & 0.00000 & 0 & 4.7985 & ⋯ & 0.000000 & 0.000000 & 4.17720 & 0.0000 & 0.071763 & 0.121680 & 0.186500 & 0.00000 & 0.200380 & 0.00000\\\\\n",
       "\tHN25\\_P25\\_B12\\_S312\\_comb & 0.000000 & 0.0000 & 0.00000 & 0.000000 & 0.00000 & 0.037031 & 0 & 0.00000 & 0 & 4.7680 & ⋯ & 0.064883 & 0.000000 & 0.00000 & 0.0000 & 0.049631 & 0.081340 & 1.270200 & 2.32910 & 1.390100 & 0.00000\\\\\n",
       "\t⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋱ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n",
       "\tHNSCC17\\_P4\\_A08\\_S104\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 0.00000 & 0 & 2.58470 & ⋯ & 0.00000 & 0.000000 & 1.03490 & 4.1908 & 1.007200 & 0.140120 & 0.063503 & 1.41140 & 0.025738 & 1.335700\\\\\n",
       "\tHNSCC17\\_P4\\_E10\\_S154\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 0.00000 & 0 & 4.23760 & ⋯ & 0.00000 & 0.000000 & 0.00000 & 0.0000 & 0.021480 & 0.000000 & 0.057970 & 1.77400 & 0.000000 & 0.000000\\\\\n",
       "\tHNSCC17\\_P4\\_E02\\_S146\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 3.012700 & 0 & 0.00000 & 0 & 0.00000 & ⋯ & 0.00000 & 0.000000 & 0.00000 & 0.0000 & 0.000000 & 0.000000 & 0.591680 & 3.63160 & 0.000000 & 0.000000\\\\\n",
       "\tHNSCC20\\_P13\\_F10\\_S262\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 4.84390 & 0 & 4.82620 & ⋯ & 0.00000 & 0.331130 & 0.00000 & 0.0000 & 0.000000 & 0.000000 & 0.000000 & 0.00000 & 0.000000 & 3.520300\\\\\n",
       "\tHNSCC17\\_P4\\_D04\\_S136\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.063503 & 0 & 0.43403 & 0 & 0.28214 & ⋯ & 0.00000 & 0.000000 & 0.00000 & 0.0000 & 0.022900 & 0.067639 & 0.032806 & 4.04410 & 0.505890 & 0.000000\\\\\n",
       "\tHNSCC20\\_P13\\_C06\\_S222\\_comb & 0.00000 & 0.0000 & 0.046840 & 0 & 0 & 0.000000 & 0 & 5.43390 & 0 & 0.00000 & ⋯ & 1.68210 & 0.000000 & 0.00000 & 0.0000 & 0.235110 & 0.182690 & 0.231430 & 0.00000 & 1.938100 & 3.675800\\\\\n",
       "\tHNSCC20\\_P13\\_C12\\_S228\\_comb & 1.11240 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 2.33490 & 0 & 3.09170 & ⋯ & 0.00000 & 3.823400 & 0.00000 & 0.0000 & 1.292200 & 0.000000 & 0.718960 & 2.78470 & 0.000000 & 0.000000\\\\\n",
       "\tHNSCC17\\_P4\\_H04\\_S184\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 1.22090 & 0 & 3.91210 & ⋯ & 0.00000 & 3.586600 & 0.54300 & 0.0000 & 0.000000 & 0.000000 & 0.000000 & 0.63506 & 0.000000 & 0.000000\\\\\n",
       "\tHNSCC17\\_P4\\_C06\\_S126\\_comb & 0.99132 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 1.24370 & 0 & 0.00000 & ⋯ & 0.00000 & 0.000000 & 2.28950 & 0.0000 & 0.452070 & 0.000000 & 0.000000 & 2.11300 & 0.000000 & 0.530070\\\\\n",
       "\tHNSCC20\\_P3\\_D01\\_S37\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 4.28630 & 0 & 3.29500 & ⋯ & 0.00000 & 3.167700 & 0.00000 & 4.3682 & 0.493650 & 0.078610 & 0.092207 & 3.20070 & 0.000000 & 0.000000\\\\\n",
       "\tHNSCC20\\_P3\\_D09\\_S45\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.096262 & 0 & 4.38340 & 0 & 0.00000 & ⋯ & 0.00000 & 0.000000 & 0.00000 & 0.0000 & 0.000000 & 0.107020 & 0.000000 & 0.00000 & 0.000000 & 2.838800\\\\\n",
       "\tHNSCC17\\_P4\\_E06\\_S150\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.574340 & 0 & 0.00000 & 0 & 0.00000 & ⋯ & 2.89380 & 2.428700 & 0.00000 & 0.0000 & 0.015783 & 0.132250 & 0.000000 & 3.74010 & 0.000000 & 0.000000\\\\\n",
       "\tHNSCC20\\_P13\\_H10\\_S286\\_comb & 0.00000 & 0.0000 & 0.048236 & 0 & 0 & 3.034200 & 0 & 4.05260 & 0 & 3.51260 & ⋯ & 2.55780 & 2.573600 & 3.39900 & 5.6353 & 0.039840 & 1.006500 & 0.056584 & 0.00000 & 0.000000 & 3.643400\\\\\n",
       "\tHNSCC17\\_P4\\_A02\\_S98\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.138810 & 0 & 0.00000 & 0 & 0.00000 & ⋯ & 0.00000 & 0.090853 & 0.00000 & 0.0000 & 0.141430 & 0.147960 & 0.149260 & 4.10650 & 0.000000 & 0.000000\\\\\n",
       "\tHNSCC20\\_P13\\_D01\\_S229\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 5.22440 & 0 & 0.00000 & ⋯ & 0.00000 & 3.206500 & 3.06590 & 0.0000 & 0.063503 & 0.000000 & 0.000000 & 0.00000 & 1.423300 & 0.000000\\\\\n",
       "\tHNSCC20\\_P13\\_G02\\_S266\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 4.14670 & 0 & 1.15960 & ⋯ & 0.00000 & 0.000000 & 0.00000 & 0.0000 & 0.066261 & 0.246100 & 0.109690 & 0.00000 & 0.000000 & 0.000000\\\\\n",
       "\tHNSCC17\\_P4\\_B04\\_S112\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 0.00000 & 0 & 3.43500 & ⋯ & 0.00000 & 0.000000 & 3.57950 & 4.5380 & 1.914900 & 0.053806 & 0.107020 & 0.94785 & 0.000000 & 0.000000\\\\\n",
       "\tHNSCC17\\_P4\\_C09\\_S129\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 2.56540 & 0 & 0.00000 & ⋯ & 0.00000 & 0.000000 & 0.00000 & 0.0000 & 3.109000 & 0.055196 & 0.066261 & 4.27180 & 0.000000 & 0.000000\\\\\n",
       "\tHNSCC20\\_P13\\_A12\\_S204\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 5.308300 & 0 & 3.65020 & 0 & 0.00000 & ⋯ & 0.00000 & 0.000000 & 0.00000 & 0.0000 & 0.077243 & 0.000000 & 0.000000 & 0.19409 & 1.190900 & 1.174400\\\\\n",
       "\tHNSCC17\\_P4\\_F06\\_S162\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 0.00000 & 0 & 0.00000 & ⋯ & 0.00000 & 0.000000 & 0.00000 & 4.6224 & 0.244890 & 0.116360 & 0.117700 & 0.00000 & 0.000000 & 0.000000\\\\\n",
       "\tHNSCC20\\_P3\\_B10\\_S22\\_comb & 0.63320 & 0.0000 & 0.000000 & 0 & 0 & 0.311500 & 0 & 5.18090 & 0 & 0.00000 & ⋯ & 1.00070 & 2.346200 & 1.55140 & 3.0491 & 1.441500 & 0.000000 & 0.737250 & 3.38280 & 0.107020 & 2.233300\\\\\n",
       "\tHNSCC20\\_P13\\_B11\\_S215\\_comb & 1.22590 & 1.0642 & 0.000000 & 0 & 0 & 5.735100 & 0 & 3.65520 & 0 & 2.04050 & ⋯ & 0.00000 & 2.066300 & 2.88520 & 4.5492 & 0.000000 & 0.201630 & 0.000000 & 1.00070 & 0.575310 & 1.680800\\\\\n",
       "\tHNSCC20\\_P3\\_C08\\_S32\\_comb & 1.37740 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 5.05750 & 0 & 3.31510 & ⋯ & 0.00000 & 0.000000 & 2.12200 & 0.0000 & 0.041243 & 0.000000 & 0.000000 & 2.52430 & 0.172490 & 0.000000\\\\\n",
       "\tHNSCC17\\_P4\\_H03\\_S183\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 0.00000 & 0 & 4.38080 & ⋯ & 0.00000 & 4.277300 & 0.00000 & 4.5356 & 0.012926 & 0.000000 & 0.037031 & 0.00000 & 0.000000 & 0.000000\\\\\n",
       "\tHNSCC20\\_P3\\_F09\\_S69\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 2.68890 & 0 & 0.00000 & ⋯ & 0.00000 & 0.000000 & 0.00000 & 0.0000 & 0.606920 & 0.000000 & 0.039840 & 0.67717 & 1.017900 & 0.071763\\\\\n",
       "\tHNSCC17\\_P4\\_G12\\_S180\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 0.00000 & 0 & 0.00000 & ⋯ & 2.25850 & 0.000000 & 0.00000 & 0.0000 & 4.188600 & 0.398350 & 0.254590 & 0.75275 & 0.000000 & 0.000000\\\\\n",
       "\tHNSCC20\\_P13\\_C05\\_S221\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 5.08770 & 0 & 0.00000 & ⋯ & 0.48954 & 0.000000 & 0.00000 & 0.0000 & 0.247320 & 0.746740 & 0.318460 & 0.00000 & 0.000000 & 0.000000\\\\\n",
       "\tHNSCC17\\_P4\\_C12\\_S132\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 0.042644 & 0 & 1.81110 & 0 & 3.65280 & ⋯ & 0.00000 & 3.737300 & 0.10165 & 3.4737 & 0.000000 & 0.000000 & 2.106300 & 4.05570 & 0.000000 & 0.000000\\\\\n",
       "\tHNSCC20\\_P3\\_H08\\_S92\\_comb & 2.99960 & 0.0000 & 0.000000 & 0 & 0 & 0.000000 & 0 & 3.83700 & 0 & 4.07110 & ⋯ & 3.78200 & 0.000000 & 3.59690 & 0.0000 & 0.157040 & 0.236340 & 0.291600 & 3.73420 & 0.000000 & 0.000000\\\\\n",
       "\tHNSCC20\\_P3\\_G06\\_S78\\_comb & 0.00000 & 0.0000 & 0.000000 & 0 & 0 & 3.406000 & 0 & 4.34800 & 0 & 0.00000 & ⋯ & 0.00000 & 0.000000 & 0.00000 & 0.0000 & 0.034216 & 0.000000 & 0.111030 & 0.00000 & 0.000000 & 0.000000\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A matrix: 5902 × 18332 of type dbl\n",
       "\n",
       "| <!--/--> | ENSG00000121410 | ENSG00000268895 | ENSG00000148584 | ENSG00000175899 | ENSG00000245105 | ENSG00000166535 | ENSG00000256069 | ENSG00000128274 | ENSG00000118017 | ENSG00000094914 | ⋯ | ENSG00000153975 | ENSG00000086827 | ENSG00000174442 | ENSG00000122952 | ENSG00000070476 | ENSG00000203995 | ENSG00000162378 | ENSG00000159840 | ENSG00000074755 | ENSG00000036549 |\n",
       "|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|\n",
       "| HN28_P15_D06_S330_comb | 0.000000 | 0.0000 | 0.00000 | 9.683000 | 0.17632 | 0.000000 | 0 | 2.24880 | 0 | 4.5423 | ⋯ | 0.000000 | 0.000000 | 0.00000 | 0.0000 | 0.121680 | 0.163500 | 0.090853 | 4.27480 | 0.000000 | 0.00000 |\n",
       "| HN28_P6_G05_S173_comb | 0.000000 | 0.0000 | 0.00000 | 7.583000 | 0.00000 | 0.000000 | 0 | 0.00000 | 0 | 4.6920 | ⋯ | 0.000000 | 0.000000 | 0.00000 | 0.0000 | 0.195350 | 0.279770 | 3.934800 | 0.00000 | 3.771600 | 0.00000 |\n",
       "| HN26_P14_D11_S239_comb | 0.000000 | 0.0000 | 0.00000 | 0.029983 | 0.00000 | 4.798800 | 0 | 0.00000 | 0 | 0.0000 | ⋯ | 4.172500 | 0.000000 | 0.00000 | 0.0000 | 0.021480 | 0.000000 | 0.073135 | 0.00000 | 1.304500 | 2.11200 |\n",
       "| HN26_P14_H05_S281_comb | 0.000000 | 0.0000 | 0.00000 | 6.054700 | 0.00000 | 0.000000 | 0 | 0.26424 | 0 | 0.0000 | ⋯ | 0.000000 | 0.000000 | 0.00000 | 0.0000 | 0.089498 | 0.186500 | 0.214120 | 0.12433 | 0.093560 | 0.00000 |\n",
       "| HN26_P25_H09_S189_comb | 0.000000 | 0.0000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 | 0 | 0.00000 | 0 | 4.7785 | ⋯ | 0.000000 | 0.000000 | 0.00000 | 0.0000 | 0.228970 | 0.133560 | 2.905900 | 3.00340 | 0.000000 | 0.00000 |\n",
       "| HN26_P14_H06_S282_comb | 0.066261 | 0.0000 | 0.00000 | 0.000000 | 0.00000 | 2.283000 | 0 | 0.00000 | 0 | 3.1225 | ⋯ | 0.000000 | 2.017200 | 0.87184 | 0.0000 | 1.201600 | 0.063503 | 0.051024 | 0.60502 | 0.000000 | 0.00000 |\n",
       "| HN25_P25_C04_S316_comb | 0.000000 | 0.0000 | 0.00000 | 0.196610 | 0.00000 | 0.000000 | 0 | 0.00000 | 0 | 5.3764 | ⋯ | 4.397100 | 0.000000 | 0.00000 | 0.0000 | 0.362890 | 1.088100 | 0.855990 | 0.00000 | 0.856790 | 0.00000 |\n",
       "| HN26_P25_A11_S107_comb | 0.541020 | 0.0000 | 0.00000 | 7.706000 | 0.00000 | 0.000000 | 0 | 0.00000 | 0 | 4.1304 | ⋯ | 0.000000 | 4.216400 | 4.63480 | 0.0000 | 0.097611 | 0.067639 | 0.000000 | 5.29280 | 0.000000 | 0.00000 |\n",
       "| HN26_P25_C09_S129_comb | 0.000000 | 0.0000 | 0.00000 | 0.000000 | 0.00000 | 1.125000 | 0 | 0.00000 | 0 | 0.0000 | ⋯ | 4.787500 | 0.000000 | 0.00000 | 0.0000 | 0.062122 | 0.032806 | 0.092207 | 0.00000 | 0.017209 | 0.00000 |\n",
       "| HNSCC26_P24_H05_S377_comb | 1.300400 | 0.0000 | 0.00000 | 0.000000 | 2.61920 | 0.125650 | 0 | 0.00000 | 0 | 0.0000 | ⋯ | 0.000000 | 0.000000 | 0.00000 | 0.0000 | 0.622930 | 0.221570 | 0.420080 | 0.55680 | 0.000000 | 0.00000 |\n",
       "| HN25_P5_E10_S58_comb | 1.983300 | 0.0000 | 0.00000 | 7.285600 | 0.00000 | 0.000000 | 0 | 4.44510 | 0 | 0.0000 | ⋯ | 0.000000 | 4.317400 | 0.00000 | 0.0000 | 0.028569 | 0.332280 | 0.313830 | 3.91660 | 0.000000 | 0.00000 |\n",
       "| HN25_P24_B02_S110_comb | 0.000000 | 0.0000 | 0.00000 | 0.000000 | 0.00000 | 1.950500 | 0 | 0.00000 | 0 | 3.0177 | ⋯ | 1.237600 | 2.535600 | 0.00000 | 3.7281 | 0.000000 | 0.000000 | 1.046800 | 1.93810 | 0.236340 | 0.44679 |\n",
       "| HN25_P25_C01_S313_comb | 0.000000 | 0.0000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 | 0 | 0.00000 | 0 | 0.0000 | ⋯ | 0.000000 | 0.000000 | 0.00000 | 0.0000 | 0.100300 | 0.591680 | 0.189030 | 0.00000 | 0.000000 | 0.00000 |\n",
       "| HN28_P15_G06_S366_comb | 0.000000 | 0.0000 | 0.00000 | 7.852500 | 0.00000 | 0.000000 | 0 | 0.00000 | 0 | 5.7214 | ⋯ | 0.000000 | 0.000000 | 0.00000 | 4.3319 | 0.000000 | 0.000000 | 0.358400 | 4.37100 | 0.000000 | 0.00000 |\n",
       "| HN26_P6_B06_S18_comb | 0.000000 | 0.0000 | 0.00000 | 8.313600 | 0.00000 | 0.000000 | 0 | 0.00000 | 0 | 0.0000 | ⋯ | 0.000000 | 0.000000 | 7.03750 | 0.0000 | 0.123000 | 0.221570 | 0.254590 | 0.00000 | 0.000000 | 0.00000 |\n",
       "| HN25_P5_C05_S29_comb | 0.000000 | 0.0000 | 0.00000 | 0.049631 | 0.00000 | 0.000000 | 0 | 2.14960 | 0 | 0.0000 | ⋯ | 0.000000 | 0.079975 | 0.00000 | 0.0000 | 0.066261 | 0.000000 | 0.639700 | 3.17600 | 0.000000 | 0.00000 |\n",
       "| HN28_P6_D09_S141_comb | 0.000000 | 0.0000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 | 0 | 0.00000 | 0 | 0.0000 | ⋯ | 0.000000 | 0.000000 | 0.00000 | 0.0000 | 0.000000 | 0.000000 | 0.458380 | 2.23330 | 0.000000 | 0.00000 |\n",
       "| HN26_P5_H01_S85_comb | 0.000000 | 0.0000 | 0.00000 | 0.000000 | 0.00000 | 4.807000 | 0 | 2.04540 | 0 | 4.4487 | ⋯ | 0.000000 | 0.000000 | 0.00000 | 0.0000 | 0.146660 | 0.125650 | 2.171200 | 0.00000 | 0.000000 | 0.00000 |\n",
       "| HN26_P13_D07_S139_comb | 0.000000 | 0.0000 | 0.00000 | 8.063000 | 0.00000 | 0.000000 | 0 | 0.00000 | 0 | 0.0000 | ⋯ | 0.000000 | 0.000000 | 0.00000 | 0.0000 | 0.000000 | 0.183960 | 0.182690 | 6.79850 | 0.000000 | 0.00000 |\n",
       "| HN26_P5_E06_S54_comb | 0.000000 | 0.0000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 | 0 | 1.24370 | 0 | 4.2672 | ⋯ | 0.000000 | 0.000000 | 0.00000 | 0.0000 | 0.018634 | 0.142740 | 0.098958 | 2.68890 | 0.000000 | 3.05260 |\n",
       "| HN26_P26_H05_S377_comb | 0.000000 | 0.0000 | 0.00000 | 0.000000 | 0.00000 | 1.495700 | 0 | 0.00000 | 0 | 0.0000 | ⋯ | 0.000000 | 0.000000 | 0.00000 | 0.0000 | 0.066261 | 0.073135 | 0.045443 | 0.00000 | 0.017209 | 2.39230 |\n",
       "| HNSCC26_P24_F12_S360_comb | 0.000000 | 0.0000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 | 0 | 0.00000 | 0 | 3.9039 | ⋯ | 0.000000 | 0.000000 | 0.00000 | 0.0000 | 0.053806 | 0.417920 | 0.125650 | 2.63830 | 0.000000 | 0.00000 |\n",
       "| HNSCC26_P24_F03_S351_comb | 0.000000 | 0.0000 | 0.00000 | 0.000000 | 0.00000 | 0.000000 | 0 | 2.30680 | 0 | 0.0000 | ⋯ | 0.000000 | 0.000000 | 0.00000 | 0.0000 | 0.000000 | 0.069015 | 0.105680 | 0.00000 | 0.000000 | 0.00000 |\n",
       "| HN26_P6_D08_S44_comb | 0.000000 | 0.0000 | 0.00000 | 0.000000 | 0.00000 | 5.313100 | 0 | 0.00000 | 0 | 0.0000 | ⋯ | 0.000000 | 2.457100 | 0.00000 | 0.0000 | 0.032806 | 0.108360 | 0.134880 | 1.52460 | 1.202900 | 0.00000 |\n",
       "| HN25_P5_E12_S60_comb | 0.000000 | 2.0635 | 0.00000 | 9.080900 | 0.00000 | 0.000000 | 0 | 0.58496 | 0 | 0.0000 | ⋯ | 0.000000 | 4.536200 | 0.00000 | 0.0000 | 0.105680 | 0.000000 | 0.082703 | 3.89960 | 1.488500 | 0.00000 |\n",
       "| HNSCC26_P24_C01_S313_comb | 0.000000 | 0.0000 | 0.00000 | 0.000000 | 0.00000 | 2.468100 | 0 | 0.00000 | 0 | 0.0000 | ⋯ | 0.000000 | 3.812700 | 0.00000 | 3.1533 | 0.024320 | 0.137500 | 0.478200 | 0.00000 | 1.371800 | 1.93050 |\n",
       "| HN25_P5_F01_S61_comb | 0.000000 | 0.0000 | 0.00000 | 9.708900 | 0.00000 | 0.173770 | 0 | 0.00000 | 0 | 0.0000 | ⋯ | 0.000000 | 0.000000 | 0.00000 | 0.0000 | 0.064883 | 0.159630 | 0.000000 | 3.45250 | 0.000000 | 0.00000 |\n",
       "| HN26_P5_D12_S48_comb | 0.000000 | 0.0000 | 0.00000 | 8.795600 | 0.00000 | 0.000000 | 0 | 0.00000 | 0 | 0.0000 | ⋯ | 0.000000 | 0.000000 | 0.00000 | 0.0000 | 4.464900 | 0.735520 | 0.626670 | 5.48910 | 0.000000 | 0.00000 |\n",
       "| HN25_P25_C11_S323_comb | 0.000000 | 0.0000 | 0.02148 | 4.939200 | 0.00000 | 0.000000 | 0 | 0.00000 | 0 | 4.7985 | ⋯ | 0.000000 | 0.000000 | 4.17720 | 0.0000 | 0.071763 | 0.121680 | 0.186500 | 0.00000 | 0.200380 | 0.00000 |\n",
       "| HN25_P25_B12_S312_comb | 0.000000 | 0.0000 | 0.00000 | 0.000000 | 0.00000 | 0.037031 | 0 | 0.00000 | 0 | 4.7680 | ⋯ | 0.064883 | 0.000000 | 0.00000 | 0.0000 | 0.049631 | 0.081340 | 1.270200 | 2.32910 | 1.390100 | 0.00000 |\n",
       "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋱ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ |\n",
       "| HNSCC17_P4_A08_S104_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 0.00000 | 0 | 2.58470 | ⋯ | 0.00000 | 0.000000 | 1.03490 | 4.1908 | 1.007200 | 0.140120 | 0.063503 | 1.41140 | 0.025738 | 1.335700 |\n",
       "| HNSCC17_P4_E10_S154_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 0.00000 | 0 | 4.23760 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.0000 | 0.021480 | 0.000000 | 0.057970 | 1.77400 | 0.000000 | 0.000000 |\n",
       "| HNSCC17_P4_E02_S146_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 3.012700 | 0 | 0.00000 | 0 | 0.00000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.0000 | 0.000000 | 0.000000 | 0.591680 | 3.63160 | 0.000000 | 0.000000 |\n",
       "| HNSCC20_P13_F10_S262_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 4.84390 | 0 | 4.82620 | ⋯ | 0.00000 | 0.331130 | 0.00000 | 0.0000 | 0.000000 | 0.000000 | 0.000000 | 0.00000 | 0.000000 | 3.520300 |\n",
       "| HNSCC17_P4_D04_S136_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.063503 | 0 | 0.43403 | 0 | 0.28214 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.0000 | 0.022900 | 0.067639 | 0.032806 | 4.04410 | 0.505890 | 0.000000 |\n",
       "| HNSCC20_P13_C06_S222_comb | 0.00000 | 0.0000 | 0.046840 | 0 | 0 | 0.000000 | 0 | 5.43390 | 0 | 0.00000 | ⋯ | 1.68210 | 0.000000 | 0.00000 | 0.0000 | 0.235110 | 0.182690 | 0.231430 | 0.00000 | 1.938100 | 3.675800 |\n",
       "| HNSCC20_P13_C12_S228_comb | 1.11240 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 2.33490 | 0 | 3.09170 | ⋯ | 0.00000 | 3.823400 | 0.00000 | 0.0000 | 1.292200 | 0.000000 | 0.718960 | 2.78470 | 0.000000 | 0.000000 |\n",
       "| HNSCC17_P4_H04_S184_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 1.22090 | 0 | 3.91210 | ⋯ | 0.00000 | 3.586600 | 0.54300 | 0.0000 | 0.000000 | 0.000000 | 0.000000 | 0.63506 | 0.000000 | 0.000000 |\n",
       "| HNSCC17_P4_C06_S126_comb | 0.99132 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 1.24370 | 0 | 0.00000 | ⋯ | 0.00000 | 0.000000 | 2.28950 | 0.0000 | 0.452070 | 0.000000 | 0.000000 | 2.11300 | 0.000000 | 0.530070 |\n",
       "| HNSCC20_P3_D01_S37_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 4.28630 | 0 | 3.29500 | ⋯ | 0.00000 | 3.167700 | 0.00000 | 4.3682 | 0.493650 | 0.078610 | 0.092207 | 3.20070 | 0.000000 | 0.000000 |\n",
       "| HNSCC20_P3_D09_S45_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.096262 | 0 | 4.38340 | 0 | 0.00000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.0000 | 0.000000 | 0.107020 | 0.000000 | 0.00000 | 0.000000 | 2.838800 |\n",
       "| HNSCC17_P4_E06_S150_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.574340 | 0 | 0.00000 | 0 | 0.00000 | ⋯ | 2.89380 | 2.428700 | 0.00000 | 0.0000 | 0.015783 | 0.132250 | 0.000000 | 3.74010 | 0.000000 | 0.000000 |\n",
       "| HNSCC20_P13_H10_S286_comb | 0.00000 | 0.0000 | 0.048236 | 0 | 0 | 3.034200 | 0 | 4.05260 | 0 | 3.51260 | ⋯ | 2.55780 | 2.573600 | 3.39900 | 5.6353 | 0.039840 | 1.006500 | 0.056584 | 0.00000 | 0.000000 | 3.643400 |\n",
       "| HNSCC17_P4_A02_S98_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.138810 | 0 | 0.00000 | 0 | 0.00000 | ⋯ | 0.00000 | 0.090853 | 0.00000 | 0.0000 | 0.141430 | 0.147960 | 0.149260 | 4.10650 | 0.000000 | 0.000000 |\n",
       "| HNSCC20_P13_D01_S229_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 5.22440 | 0 | 0.00000 | ⋯ | 0.00000 | 3.206500 | 3.06590 | 0.0000 | 0.063503 | 0.000000 | 0.000000 | 0.00000 | 1.423300 | 0.000000 |\n",
       "| HNSCC20_P13_G02_S266_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 4.14670 | 0 | 1.15960 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.0000 | 0.066261 | 0.246100 | 0.109690 | 0.00000 | 0.000000 | 0.000000 |\n",
       "| HNSCC17_P4_B04_S112_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 0.00000 | 0 | 3.43500 | ⋯ | 0.00000 | 0.000000 | 3.57950 | 4.5380 | 1.914900 | 0.053806 | 0.107020 | 0.94785 | 0.000000 | 0.000000 |\n",
       "| HNSCC17_P4_C09_S129_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 2.56540 | 0 | 0.00000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.0000 | 3.109000 | 0.055196 | 0.066261 | 4.27180 | 0.000000 | 0.000000 |\n",
       "| HNSCC20_P13_A12_S204_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 5.308300 | 0 | 3.65020 | 0 | 0.00000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.0000 | 0.077243 | 0.000000 | 0.000000 | 0.19409 | 1.190900 | 1.174400 |\n",
       "| HNSCC17_P4_F06_S162_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 0.00000 | 0 | 0.00000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 4.6224 | 0.244890 | 0.116360 | 0.117700 | 0.00000 | 0.000000 | 0.000000 |\n",
       "| HNSCC20_P3_B10_S22_comb | 0.63320 | 0.0000 | 0.000000 | 0 | 0 | 0.311500 | 0 | 5.18090 | 0 | 0.00000 | ⋯ | 1.00070 | 2.346200 | 1.55140 | 3.0491 | 1.441500 | 0.000000 | 0.737250 | 3.38280 | 0.107020 | 2.233300 |\n",
       "| HNSCC20_P13_B11_S215_comb | 1.22590 | 1.0642 | 0.000000 | 0 | 0 | 5.735100 | 0 | 3.65520 | 0 | 2.04050 | ⋯ | 0.00000 | 2.066300 | 2.88520 | 4.5492 | 0.000000 | 0.201630 | 0.000000 | 1.00070 | 0.575310 | 1.680800 |\n",
       "| HNSCC20_P3_C08_S32_comb | 1.37740 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 5.05750 | 0 | 3.31510 | ⋯ | 0.00000 | 0.000000 | 2.12200 | 0.0000 | 0.041243 | 0.000000 | 0.000000 | 2.52430 | 0.172490 | 0.000000 |\n",
       "| HNSCC17_P4_H03_S183_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 0.00000 | 0 | 4.38080 | ⋯ | 0.00000 | 4.277300 | 0.00000 | 4.5356 | 0.012926 | 0.000000 | 0.037031 | 0.00000 | 0.000000 | 0.000000 |\n",
       "| HNSCC20_P3_F09_S69_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 2.68890 | 0 | 0.00000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.0000 | 0.606920 | 0.000000 | 0.039840 | 0.67717 | 1.017900 | 0.071763 |\n",
       "| HNSCC17_P4_G12_S180_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 0.00000 | 0 | 0.00000 | ⋯ | 2.25850 | 0.000000 | 0.00000 | 0.0000 | 4.188600 | 0.398350 | 0.254590 | 0.75275 | 0.000000 | 0.000000 |\n",
       "| HNSCC20_P13_C05_S221_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 5.08770 | 0 | 0.00000 | ⋯ | 0.48954 | 0.000000 | 0.00000 | 0.0000 | 0.247320 | 0.746740 | 0.318460 | 0.00000 | 0.000000 | 0.000000 |\n",
       "| HNSCC17_P4_C12_S132_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 0.042644 | 0 | 1.81110 | 0 | 3.65280 | ⋯ | 0.00000 | 3.737300 | 0.10165 | 3.4737 | 0.000000 | 0.000000 | 2.106300 | 4.05570 | 0.000000 | 0.000000 |\n",
       "| HNSCC20_P3_H08_S92_comb | 2.99960 | 0.0000 | 0.000000 | 0 | 0 | 0.000000 | 0 | 3.83700 | 0 | 4.07110 | ⋯ | 3.78200 | 0.000000 | 3.59690 | 0.0000 | 0.157040 | 0.236340 | 0.291600 | 3.73420 | 0.000000 | 0.000000 |\n",
       "| HNSCC20_P3_G06_S78_comb | 0.00000 | 0.0000 | 0.000000 | 0 | 0 | 3.406000 | 0 | 4.34800 | 0 | 0.00000 | ⋯ | 0.00000 | 0.000000 | 0.00000 | 0.0000 | 0.034216 | 0.000000 | 0.111030 | 0.00000 | 0.000000 | 0.000000 |\n",
       "\n"
      ],
      "text/plain": [
       "                          ENSG00000121410 ENSG00000268895 ENSG00000148584\n",
       "HN28_P15_D06_S330_comb    0.000000        0.0000          0.00000        \n",
       "HN28_P6_G05_S173_comb     0.000000        0.0000          0.00000        \n",
       "HN26_P14_D11_S239_comb    0.000000        0.0000          0.00000        \n",
       "HN26_P14_H05_S281_comb    0.000000        0.0000          0.00000        \n",
       "HN26_P25_H09_S189_comb    0.000000        0.0000          0.00000        \n",
       "HN26_P14_H06_S282_comb    0.066261        0.0000          0.00000        \n",
       "HN25_P25_C04_S316_comb    0.000000        0.0000          0.00000        \n",
       "HN26_P25_A11_S107_comb    0.541020        0.0000          0.00000        \n",
       "HN26_P25_C09_S129_comb    0.000000        0.0000          0.00000        \n",
       "HNSCC26_P24_H05_S377_comb 1.300400        0.0000          0.00000        \n",
       "HN25_P5_E10_S58_comb      1.983300        0.0000          0.00000        \n",
       "HN25_P24_B02_S110_comb    0.000000        0.0000          0.00000        \n",
       "HN25_P25_C01_S313_comb    0.000000        0.0000          0.00000        \n",
       "HN28_P15_G06_S366_comb    0.000000        0.0000          0.00000        \n",
       "HN26_P6_B06_S18_comb      0.000000        0.0000          0.00000        \n",
       "HN25_P5_C05_S29_comb      0.000000        0.0000          0.00000        \n",
       "HN28_P6_D09_S141_comb     0.000000        0.0000          0.00000        \n",
       "HN26_P5_H01_S85_comb      0.000000        0.0000          0.00000        \n",
       "HN26_P13_D07_S139_comb    0.000000        0.0000          0.00000        \n",
       "HN26_P5_E06_S54_comb      0.000000        0.0000          0.00000        \n",
       "HN26_P26_H05_S377_comb    0.000000        0.0000          0.00000        \n",
       "HNSCC26_P24_F12_S360_comb 0.000000        0.0000          0.00000        \n",
       "HNSCC26_P24_F03_S351_comb 0.000000        0.0000          0.00000        \n",
       "HN26_P6_D08_S44_comb      0.000000        0.0000          0.00000        \n",
       "HN25_P5_E12_S60_comb      0.000000        2.0635          0.00000        \n",
       "HNSCC26_P24_C01_S313_comb 0.000000        0.0000          0.00000        \n",
       "HN25_P5_F01_S61_comb      0.000000        0.0000          0.00000        \n",
       "HN26_P5_D12_S48_comb      0.000000        0.0000          0.00000        \n",
       "HN25_P25_C11_S323_comb    0.000000        0.0000          0.02148        \n",
       "HN25_P25_B12_S312_comb    0.000000        0.0000          0.00000        \n",
       "⋮                         ⋮               ⋮               ⋮              \n",
       "HNSCC17_P4_A08_S104_comb  0.00000         0.0000          0.000000       \n",
       "HNSCC17_P4_E10_S154_comb  0.00000         0.0000          0.000000       \n",
       "HNSCC17_P4_E02_S146_comb  0.00000         0.0000          0.000000       \n",
       "HNSCC20_P13_F10_S262_comb 0.00000         0.0000          0.000000       \n",
       "HNSCC17_P4_D04_S136_comb  0.00000         0.0000          0.000000       \n",
       "HNSCC20_P13_C06_S222_comb 0.00000         0.0000          0.046840       \n",
       "HNSCC20_P13_C12_S228_comb 1.11240         0.0000          0.000000       \n",
       "HNSCC17_P4_H04_S184_comb  0.00000         0.0000          0.000000       \n",
       "HNSCC17_P4_C06_S126_comb  0.99132         0.0000          0.000000       \n",
       "HNSCC20_P3_D01_S37_comb   0.00000         0.0000          0.000000       \n",
       "HNSCC20_P3_D09_S45_comb   0.00000         0.0000          0.000000       \n",
       "HNSCC17_P4_E06_S150_comb  0.00000         0.0000          0.000000       \n",
       "HNSCC20_P13_H10_S286_comb 0.00000         0.0000          0.048236       \n",
       "HNSCC17_P4_A02_S98_comb   0.00000         0.0000          0.000000       \n",
       "HNSCC20_P13_D01_S229_comb 0.00000         0.0000          0.000000       \n",
       "HNSCC20_P13_G02_S266_comb 0.00000         0.0000          0.000000       \n",
       "HNSCC17_P4_B04_S112_comb  0.00000         0.0000          0.000000       \n",
       "HNSCC17_P4_C09_S129_comb  0.00000         0.0000          0.000000       \n",
       "HNSCC20_P13_A12_S204_comb 0.00000         0.0000          0.000000       \n",
       "HNSCC17_P4_F06_S162_comb  0.00000         0.0000          0.000000       \n",
       "HNSCC20_P3_B10_S22_comb   0.63320         0.0000          0.000000       \n",
       "HNSCC20_P13_B11_S215_comb 1.22590         1.0642          0.000000       \n",
       "HNSCC20_P3_C08_S32_comb   1.37740         0.0000          0.000000       \n",
       "HNSCC17_P4_H03_S183_comb  0.00000         0.0000          0.000000       \n",
       "HNSCC20_P3_F09_S69_comb   0.00000         0.0000          0.000000       \n",
       "HNSCC17_P4_G12_S180_comb  0.00000         0.0000          0.000000       \n",
       "HNSCC20_P13_C05_S221_comb 0.00000         0.0000          0.000000       \n",
       "HNSCC17_P4_C12_S132_comb  0.00000         0.0000          0.000000       \n",
       "HNSCC20_P3_H08_S92_comb   2.99960         0.0000          0.000000       \n",
       "HNSCC20_P3_G06_S78_comb   0.00000         0.0000          0.000000       \n",
       "                          ENSG00000175899 ENSG00000245105 ENSG00000166535\n",
       "HN28_P15_D06_S330_comb    9.683000        0.17632         0.000000       \n",
       "HN28_P6_G05_S173_comb     7.583000        0.00000         0.000000       \n",
       "HN26_P14_D11_S239_comb    0.029983        0.00000         4.798800       \n",
       "HN26_P14_H05_S281_comb    6.054700        0.00000         0.000000       \n",
       "HN26_P25_H09_S189_comb    0.000000        0.00000         0.000000       \n",
       "HN26_P14_H06_S282_comb    0.000000        0.00000         2.283000       \n",
       "HN25_P25_C04_S316_comb    0.196610        0.00000         0.000000       \n",
       "HN26_P25_A11_S107_comb    7.706000        0.00000         0.000000       \n",
       "HN26_P25_C09_S129_comb    0.000000        0.00000         1.125000       \n",
       "HNSCC26_P24_H05_S377_comb 0.000000        2.61920         0.125650       \n",
       "HN25_P5_E10_S58_comb      7.285600        0.00000         0.000000       \n",
       "HN25_P24_B02_S110_comb    0.000000        0.00000         1.950500       \n",
       "HN25_P25_C01_S313_comb    0.000000        0.00000         0.000000       \n",
       "HN28_P15_G06_S366_comb    7.852500        0.00000         0.000000       \n",
       "HN26_P6_B06_S18_comb      8.313600        0.00000         0.000000       \n",
       "HN25_P5_C05_S29_comb      0.049631        0.00000         0.000000       \n",
       "HN28_P6_D09_S141_comb     0.000000        0.00000         0.000000       \n",
       "HN26_P5_H01_S85_comb      0.000000        0.00000         4.807000       \n",
       "HN26_P13_D07_S139_comb    8.063000        0.00000         0.000000       \n",
       "HN26_P5_E06_S54_comb      0.000000        0.00000         0.000000       \n",
       "HN26_P26_H05_S377_comb    0.000000        0.00000         1.495700       \n",
       "HNSCC26_P24_F12_S360_comb 0.000000        0.00000         0.000000       \n",
       "HNSCC26_P24_F03_S351_comb 0.000000        0.00000         0.000000       \n",
       "HN26_P6_D08_S44_comb      0.000000        0.00000         5.313100       \n",
       "HN25_P5_E12_S60_comb      9.080900        0.00000         0.000000       \n",
       "HNSCC26_P24_C01_S313_comb 0.000000        0.00000         2.468100       \n",
       "HN25_P5_F01_S61_comb      9.708900        0.00000         0.173770       \n",
       "HN26_P5_D12_S48_comb      8.795600        0.00000         0.000000       \n",
       "HN25_P25_C11_S323_comb    4.939200        0.00000         0.000000       \n",
       "HN25_P25_B12_S312_comb    0.000000        0.00000         0.037031       \n",
       "⋮                         ⋮               ⋮               ⋮              \n",
       "HNSCC17_P4_A08_S104_comb  0               0               0.000000       \n",
       "HNSCC17_P4_E10_S154_comb  0               0               0.000000       \n",
       "HNSCC17_P4_E02_S146_comb  0               0               3.012700       \n",
       "HNSCC20_P13_F10_S262_comb 0               0               0.000000       \n",
       "HNSCC17_P4_D04_S136_comb  0               0               0.063503       \n",
       "HNSCC20_P13_C06_S222_comb 0               0               0.000000       \n",
       "HNSCC20_P13_C12_S228_comb 0               0               0.000000       \n",
       "HNSCC17_P4_H04_S184_comb  0               0               0.000000       \n",
       "HNSCC17_P4_C06_S126_comb  0               0               0.000000       \n",
       "HNSCC20_P3_D01_S37_comb   0               0               0.000000       \n",
       "HNSCC20_P3_D09_S45_comb   0               0               0.096262       \n",
       "HNSCC17_P4_E06_S150_comb  0               0               0.574340       \n",
       "HNSCC20_P13_H10_S286_comb 0               0               3.034200       \n",
       "HNSCC17_P4_A02_S98_comb   0               0               0.138810       \n",
       "HNSCC20_P13_D01_S229_comb 0               0               0.000000       \n",
       "HNSCC20_P13_G02_S266_comb 0               0               0.000000       \n",
       "HNSCC17_P4_B04_S112_comb  0               0               0.000000       \n",
       "HNSCC17_P4_C09_S129_comb  0               0               0.000000       \n",
       "HNSCC20_P13_A12_S204_comb 0               0               5.308300       \n",
       "HNSCC17_P4_F06_S162_comb  0               0               0.000000       \n",
       "HNSCC20_P3_B10_S22_comb   0               0               0.311500       \n",
       "HNSCC20_P13_B11_S215_comb 0               0               5.735100       \n",
       "HNSCC20_P3_C08_S32_comb   0               0               0.000000       \n",
       "HNSCC17_P4_H03_S183_comb  0               0               0.000000       \n",
       "HNSCC20_P3_F09_S69_comb   0               0               0.000000       \n",
       "HNSCC17_P4_G12_S180_comb  0               0               0.000000       \n",
       "HNSCC20_P13_C05_S221_comb 0               0               0.000000       \n",
       "HNSCC17_P4_C12_S132_comb  0               0               0.042644       \n",
       "HNSCC20_P3_H08_S92_comb   0               0               0.000000       \n",
       "HNSCC20_P3_G06_S78_comb   0               0               3.406000       \n",
       "                          ENSG00000256069 ENSG00000128274 ENSG00000118017\n",
       "HN28_P15_D06_S330_comb    0               2.24880         0              \n",
       "HN28_P6_G05_S173_comb     0               0.00000         0              \n",
       "HN26_P14_D11_S239_comb    0               0.00000         0              \n",
       "HN26_P14_H05_S281_comb    0               0.26424         0              \n",
       "HN26_P25_H09_S189_comb    0               0.00000         0              \n",
       "HN26_P14_H06_S282_comb    0               0.00000         0              \n",
       "HN25_P25_C04_S316_comb    0               0.00000         0              \n",
       "HN26_P25_A11_S107_comb    0               0.00000         0              \n",
       "HN26_P25_C09_S129_comb    0               0.00000         0              \n",
       "HNSCC26_P24_H05_S377_comb 0               0.00000         0              \n",
       "HN25_P5_E10_S58_comb      0               4.44510         0              \n",
       "HN25_P24_B02_S110_comb    0               0.00000         0              \n",
       "HN25_P25_C01_S313_comb    0               0.00000         0              \n",
       "HN28_P15_G06_S366_comb    0               0.00000         0              \n",
       "HN26_P6_B06_S18_comb      0               0.00000         0              \n",
       "HN25_P5_C05_S29_comb      0               2.14960         0              \n",
       "HN28_P6_D09_S141_comb     0               0.00000         0              \n",
       "HN26_P5_H01_S85_comb      0               2.04540         0              \n",
       "HN26_P13_D07_S139_comb    0               0.00000         0              \n",
       "HN26_P5_E06_S54_comb      0               1.24370         0              \n",
       "HN26_P26_H05_S377_comb    0               0.00000         0              \n",
       "HNSCC26_P24_F12_S360_comb 0               0.00000         0              \n",
       "HNSCC26_P24_F03_S351_comb 0               2.30680         0              \n",
       "HN26_P6_D08_S44_comb      0               0.00000         0              \n",
       "HN25_P5_E12_S60_comb      0               0.58496         0              \n",
       "HNSCC26_P24_C01_S313_comb 0               0.00000         0              \n",
       "HN25_P5_F01_S61_comb      0               0.00000         0              \n",
       "HN26_P5_D12_S48_comb      0               0.00000         0              \n",
       "HN25_P25_C11_S323_comb    0               0.00000         0              \n",
       "HN25_P25_B12_S312_comb    0               0.00000         0              \n",
       "⋮                         ⋮               ⋮               ⋮              \n",
       "HNSCC17_P4_A08_S104_comb  0               0.00000         0              \n",
       "HNSCC17_P4_E10_S154_comb  0               0.00000         0              \n",
       "HNSCC17_P4_E02_S146_comb  0               0.00000         0              \n",
       "HNSCC20_P13_F10_S262_comb 0               4.84390         0              \n",
       "HNSCC17_P4_D04_S136_comb  0               0.43403         0              \n",
       "HNSCC20_P13_C06_S222_comb 0               5.43390         0              \n",
       "HNSCC20_P13_C12_S228_comb 0               2.33490         0              \n",
       "HNSCC17_P4_H04_S184_comb  0               1.22090         0              \n",
       "HNSCC17_P4_C06_S126_comb  0               1.24370         0              \n",
       "HNSCC20_P3_D01_S37_comb   0               4.28630         0              \n",
       "HNSCC20_P3_D09_S45_comb   0               4.38340         0              \n",
       "HNSCC17_P4_E06_S150_comb  0               0.00000         0              \n",
       "HNSCC20_P13_H10_S286_comb 0               4.05260         0              \n",
       "HNSCC17_P4_A02_S98_comb   0               0.00000         0              \n",
       "HNSCC20_P13_D01_S229_comb 0               5.22440         0              \n",
       "HNSCC20_P13_G02_S266_comb 0               4.14670         0              \n",
       "HNSCC17_P4_B04_S112_comb  0               0.00000         0              \n",
       "HNSCC17_P4_C09_S129_comb  0               2.56540         0              \n",
       "HNSCC20_P13_A12_S204_comb 0               3.65020         0              \n",
       "HNSCC17_P4_F06_S162_comb  0               0.00000         0              \n",
       "HNSCC20_P3_B10_S22_comb   0               5.18090         0              \n",
       "HNSCC20_P13_B11_S215_comb 0               3.65520         0              \n",
       "HNSCC20_P3_C08_S32_comb   0               5.05750         0              \n",
       "HNSCC17_P4_H03_S183_comb  0               0.00000         0              \n",
       "HNSCC20_P3_F09_S69_comb   0               2.68890         0              \n",
       "HNSCC17_P4_G12_S180_comb  0               0.00000         0              \n",
       "HNSCC20_P13_C05_S221_comb 0               5.08770         0              \n",
       "HNSCC17_P4_C12_S132_comb  0               1.81110         0              \n",
       "HNSCC20_P3_H08_S92_comb   0               3.83700         0              \n",
       "HNSCC20_P3_G06_S78_comb   0               4.34800         0              \n",
       "                          ENSG00000094914 ⋯ ENSG00000153975 ENSG00000086827\n",
       "HN28_P15_D06_S330_comb    4.5423          ⋯ 0.000000        0.000000       \n",
       "HN28_P6_G05_S173_comb     4.6920          ⋯ 0.000000        0.000000       \n",
       "HN26_P14_D11_S239_comb    0.0000          ⋯ 4.172500        0.000000       \n",
       "HN26_P14_H05_S281_comb    0.0000          ⋯ 0.000000        0.000000       \n",
       "HN26_P25_H09_S189_comb    4.7785          ⋯ 0.000000        0.000000       \n",
       "HN26_P14_H06_S282_comb    3.1225          ⋯ 0.000000        2.017200       \n",
       "HN25_P25_C04_S316_comb    5.3764          ⋯ 4.397100        0.000000       \n",
       "HN26_P25_A11_S107_comb    4.1304          ⋯ 0.000000        4.216400       \n",
       "HN26_P25_C09_S129_comb    0.0000          ⋯ 4.787500        0.000000       \n",
       "HNSCC26_P24_H05_S377_comb 0.0000          ⋯ 0.000000        0.000000       \n",
       "HN25_P5_E10_S58_comb      0.0000          ⋯ 0.000000        4.317400       \n",
       "HN25_P24_B02_S110_comb    3.0177          ⋯ 1.237600        2.535600       \n",
       "HN25_P25_C01_S313_comb    0.0000          ⋯ 0.000000        0.000000       \n",
       "HN28_P15_G06_S366_comb    5.7214          ⋯ 0.000000        0.000000       \n",
       "HN26_P6_B06_S18_comb      0.0000          ⋯ 0.000000        0.000000       \n",
       "HN25_P5_C05_S29_comb      0.0000          ⋯ 0.000000        0.079975       \n",
       "HN28_P6_D09_S141_comb     0.0000          ⋯ 0.000000        0.000000       \n",
       "HN26_P5_H01_S85_comb      4.4487          ⋯ 0.000000        0.000000       \n",
       "HN26_P13_D07_S139_comb    0.0000          ⋯ 0.000000        0.000000       \n",
       "HN26_P5_E06_S54_comb      4.2672          ⋯ 0.000000        0.000000       \n",
       "HN26_P26_H05_S377_comb    0.0000          ⋯ 0.000000        0.000000       \n",
       "HNSCC26_P24_F12_S360_comb 3.9039          ⋯ 0.000000        0.000000       \n",
       "HNSCC26_P24_F03_S351_comb 0.0000          ⋯ 0.000000        0.000000       \n",
       "HN26_P6_D08_S44_comb      0.0000          ⋯ 0.000000        2.457100       \n",
       "HN25_P5_E12_S60_comb      0.0000          ⋯ 0.000000        4.536200       \n",
       "HNSCC26_P24_C01_S313_comb 0.0000          ⋯ 0.000000        3.812700       \n",
       "HN25_P5_F01_S61_comb      0.0000          ⋯ 0.000000        0.000000       \n",
       "HN26_P5_D12_S48_comb      0.0000          ⋯ 0.000000        0.000000       \n",
       "HN25_P25_C11_S323_comb    4.7985          ⋯ 0.000000        0.000000       \n",
       "HN25_P25_B12_S312_comb    4.7680          ⋯ 0.064883        0.000000       \n",
       "⋮                         ⋮               ⋱ ⋮               ⋮              \n",
       "HNSCC17_P4_A08_S104_comb  2.58470         ⋯ 0.00000         0.000000       \n",
       "HNSCC17_P4_E10_S154_comb  4.23760         ⋯ 0.00000         0.000000       \n",
       "HNSCC17_P4_E02_S146_comb  0.00000         ⋯ 0.00000         0.000000       \n",
       "HNSCC20_P13_F10_S262_comb 4.82620         ⋯ 0.00000         0.331130       \n",
       "HNSCC17_P4_D04_S136_comb  0.28214         ⋯ 0.00000         0.000000       \n",
       "HNSCC20_P13_C06_S222_comb 0.00000         ⋯ 1.68210         0.000000       \n",
       "HNSCC20_P13_C12_S228_comb 3.09170         ⋯ 0.00000         3.823400       \n",
       "HNSCC17_P4_H04_S184_comb  3.91210         ⋯ 0.00000         3.586600       \n",
       "HNSCC17_P4_C06_S126_comb  0.00000         ⋯ 0.00000         0.000000       \n",
       "HNSCC20_P3_D01_S37_comb   3.29500         ⋯ 0.00000         3.167700       \n",
       "HNSCC20_P3_D09_S45_comb   0.00000         ⋯ 0.00000         0.000000       \n",
       "HNSCC17_P4_E06_S150_comb  0.00000         ⋯ 2.89380         2.428700       \n",
       "HNSCC20_P13_H10_S286_comb 3.51260         ⋯ 2.55780         2.573600       \n",
       "HNSCC17_P4_A02_S98_comb   0.00000         ⋯ 0.00000         0.090853       \n",
       "HNSCC20_P13_D01_S229_comb 0.00000         ⋯ 0.00000         3.206500       \n",
       "HNSCC20_P13_G02_S266_comb 1.15960         ⋯ 0.00000         0.000000       \n",
       "HNSCC17_P4_B04_S112_comb  3.43500         ⋯ 0.00000         0.000000       \n",
       "HNSCC17_P4_C09_S129_comb  0.00000         ⋯ 0.00000         0.000000       \n",
       "HNSCC20_P13_A12_S204_comb 0.00000         ⋯ 0.00000         0.000000       \n",
       "HNSCC17_P4_F06_S162_comb  0.00000         ⋯ 0.00000         0.000000       \n",
       "HNSCC20_P3_B10_S22_comb   0.00000         ⋯ 1.00070         2.346200       \n",
       "HNSCC20_P13_B11_S215_comb 2.04050         ⋯ 0.00000         2.066300       \n",
       "HNSCC20_P3_C08_S32_comb   3.31510         ⋯ 0.00000         0.000000       \n",
       "HNSCC17_P4_H03_S183_comb  4.38080         ⋯ 0.00000         4.277300       \n",
       "HNSCC20_P3_F09_S69_comb   0.00000         ⋯ 0.00000         0.000000       \n",
       "HNSCC17_P4_G12_S180_comb  0.00000         ⋯ 2.25850         0.000000       \n",
       "HNSCC20_P13_C05_S221_comb 0.00000         ⋯ 0.48954         0.000000       \n",
       "HNSCC17_P4_C12_S132_comb  3.65280         ⋯ 0.00000         3.737300       \n",
       "HNSCC20_P3_H08_S92_comb   4.07110         ⋯ 3.78200         0.000000       \n",
       "HNSCC20_P3_G06_S78_comb   0.00000         ⋯ 0.00000         0.000000       \n",
       "                          ENSG00000174442 ENSG00000122952 ENSG00000070476\n",
       "HN28_P15_D06_S330_comb    0.00000         0.0000          0.121680       \n",
       "HN28_P6_G05_S173_comb     0.00000         0.0000          0.195350       \n",
       "HN26_P14_D11_S239_comb    0.00000         0.0000          0.021480       \n",
       "HN26_P14_H05_S281_comb    0.00000         0.0000          0.089498       \n",
       "HN26_P25_H09_S189_comb    0.00000         0.0000          0.228970       \n",
       "HN26_P14_H06_S282_comb    0.87184         0.0000          1.201600       \n",
       "HN25_P25_C04_S316_comb    0.00000         0.0000          0.362890       \n",
       "HN26_P25_A11_S107_comb    4.63480         0.0000          0.097611       \n",
       "HN26_P25_C09_S129_comb    0.00000         0.0000          0.062122       \n",
       "HNSCC26_P24_H05_S377_comb 0.00000         0.0000          0.622930       \n",
       "HN25_P5_E10_S58_comb      0.00000         0.0000          0.028569       \n",
       "HN25_P24_B02_S110_comb    0.00000         3.7281          0.000000       \n",
       "HN25_P25_C01_S313_comb    0.00000         0.0000          0.100300       \n",
       "HN28_P15_G06_S366_comb    0.00000         4.3319          0.000000       \n",
       "HN26_P6_B06_S18_comb      7.03750         0.0000          0.123000       \n",
       "HN25_P5_C05_S29_comb      0.00000         0.0000          0.066261       \n",
       "HN28_P6_D09_S141_comb     0.00000         0.0000          0.000000       \n",
       "HN26_P5_H01_S85_comb      0.00000         0.0000          0.146660       \n",
       "HN26_P13_D07_S139_comb    0.00000         0.0000          0.000000       \n",
       "HN26_P5_E06_S54_comb      0.00000         0.0000          0.018634       \n",
       "HN26_P26_H05_S377_comb    0.00000         0.0000          0.066261       \n",
       "HNSCC26_P24_F12_S360_comb 0.00000         0.0000          0.053806       \n",
       "HNSCC26_P24_F03_S351_comb 0.00000         0.0000          0.000000       \n",
       "HN26_P6_D08_S44_comb      0.00000         0.0000          0.032806       \n",
       "HN25_P5_E12_S60_comb      0.00000         0.0000          0.105680       \n",
       "HNSCC26_P24_C01_S313_comb 0.00000         3.1533          0.024320       \n",
       "HN25_P5_F01_S61_comb      0.00000         0.0000          0.064883       \n",
       "HN26_P5_D12_S48_comb      0.00000         0.0000          4.464900       \n",
       "HN25_P25_C11_S323_comb    4.17720         0.0000          0.071763       \n",
       "HN25_P25_B12_S312_comb    0.00000         0.0000          0.049631       \n",
       "⋮                         ⋮               ⋮               ⋮              \n",
       "HNSCC17_P4_A08_S104_comb  1.03490         4.1908          1.007200       \n",
       "HNSCC17_P4_E10_S154_comb  0.00000         0.0000          0.021480       \n",
       "HNSCC17_P4_E02_S146_comb  0.00000         0.0000          0.000000       \n",
       "HNSCC20_P13_F10_S262_comb 0.00000         0.0000          0.000000       \n",
       "HNSCC17_P4_D04_S136_comb  0.00000         0.0000          0.022900       \n",
       "HNSCC20_P13_C06_S222_comb 0.00000         0.0000          0.235110       \n",
       "HNSCC20_P13_C12_S228_comb 0.00000         0.0000          1.292200       \n",
       "HNSCC17_P4_H04_S184_comb  0.54300         0.0000          0.000000       \n",
       "HNSCC17_P4_C06_S126_comb  2.28950         0.0000          0.452070       \n",
       "HNSCC20_P3_D01_S37_comb   0.00000         4.3682          0.493650       \n",
       "HNSCC20_P3_D09_S45_comb   0.00000         0.0000          0.000000       \n",
       "HNSCC17_P4_E06_S150_comb  0.00000         0.0000          0.015783       \n",
       "HNSCC20_P13_H10_S286_comb 3.39900         5.6353          0.039840       \n",
       "HNSCC17_P4_A02_S98_comb   0.00000         0.0000          0.141430       \n",
       "HNSCC20_P13_D01_S229_comb 3.06590         0.0000          0.063503       \n",
       "HNSCC20_P13_G02_S266_comb 0.00000         0.0000          0.066261       \n",
       "HNSCC17_P4_B04_S112_comb  3.57950         4.5380          1.914900       \n",
       "HNSCC17_P4_C09_S129_comb  0.00000         0.0000          3.109000       \n",
       "HNSCC20_P13_A12_S204_comb 0.00000         0.0000          0.077243       \n",
       "HNSCC17_P4_F06_S162_comb  0.00000         4.6224          0.244890       \n",
       "HNSCC20_P3_B10_S22_comb   1.55140         3.0491          1.441500       \n",
       "HNSCC20_P13_B11_S215_comb 2.88520         4.5492          0.000000       \n",
       "HNSCC20_P3_C08_S32_comb   2.12200         0.0000          0.041243       \n",
       "HNSCC17_P4_H03_S183_comb  0.00000         4.5356          0.012926       \n",
       "HNSCC20_P3_F09_S69_comb   0.00000         0.0000          0.606920       \n",
       "HNSCC17_P4_G12_S180_comb  0.00000         0.0000          4.188600       \n",
       "HNSCC20_P13_C05_S221_comb 0.00000         0.0000          0.247320       \n",
       "HNSCC17_P4_C12_S132_comb  0.10165         3.4737          0.000000       \n",
       "HNSCC20_P3_H08_S92_comb   3.59690         0.0000          0.157040       \n",
       "HNSCC20_P3_G06_S78_comb   0.00000         0.0000          0.034216       \n",
       "                          ENSG00000203995 ENSG00000162378 ENSG00000159840\n",
       "HN28_P15_D06_S330_comb    0.163500        0.090853        4.27480        \n",
       "HN28_P6_G05_S173_comb     0.279770        3.934800        0.00000        \n",
       "HN26_P14_D11_S239_comb    0.000000        0.073135        0.00000        \n",
       "HN26_P14_H05_S281_comb    0.186500        0.214120        0.12433        \n",
       "HN26_P25_H09_S189_comb    0.133560        2.905900        3.00340        \n",
       "HN26_P14_H06_S282_comb    0.063503        0.051024        0.60502        \n",
       "HN25_P25_C04_S316_comb    1.088100        0.855990        0.00000        \n",
       "HN26_P25_A11_S107_comb    0.067639        0.000000        5.29280        \n",
       "HN26_P25_C09_S129_comb    0.032806        0.092207        0.00000        \n",
       "HNSCC26_P24_H05_S377_comb 0.221570        0.420080        0.55680        \n",
       "HN25_P5_E10_S58_comb      0.332280        0.313830        3.91660        \n",
       "HN25_P24_B02_S110_comb    0.000000        1.046800        1.93810        \n",
       "HN25_P25_C01_S313_comb    0.591680        0.189030        0.00000        \n",
       "HN28_P15_G06_S366_comb    0.000000        0.358400        4.37100        \n",
       "HN26_P6_B06_S18_comb      0.221570        0.254590        0.00000        \n",
       "HN25_P5_C05_S29_comb      0.000000        0.639700        3.17600        \n",
       "HN28_P6_D09_S141_comb     0.000000        0.458380        2.23330        \n",
       "HN26_P5_H01_S85_comb      0.125650        2.171200        0.00000        \n",
       "HN26_P13_D07_S139_comb    0.183960        0.182690        6.79850        \n",
       "HN26_P5_E06_S54_comb      0.142740        0.098958        2.68890        \n",
       "HN26_P26_H05_S377_comb    0.073135        0.045443        0.00000        \n",
       "HNSCC26_P24_F12_S360_comb 0.417920        0.125650        2.63830        \n",
       "HNSCC26_P24_F03_S351_comb 0.069015        0.105680        0.00000        \n",
       "HN26_P6_D08_S44_comb      0.108360        0.134880        1.52460        \n",
       "HN25_P5_E12_S60_comb      0.000000        0.082703        3.89960        \n",
       "HNSCC26_P24_C01_S313_comb 0.137500        0.478200        0.00000        \n",
       "HN25_P5_F01_S61_comb      0.159630        0.000000        3.45250        \n",
       "HN26_P5_D12_S48_comb      0.735520        0.626670        5.48910        \n",
       "HN25_P25_C11_S323_comb    0.121680        0.186500        0.00000        \n",
       "HN25_P25_B12_S312_comb    0.081340        1.270200        2.32910        \n",
       "⋮                         ⋮               ⋮               ⋮              \n",
       "HNSCC17_P4_A08_S104_comb  0.140120        0.063503        1.41140        \n",
       "HNSCC17_P4_E10_S154_comb  0.000000        0.057970        1.77400        \n",
       "HNSCC17_P4_E02_S146_comb  0.000000        0.591680        3.63160        \n",
       "HNSCC20_P13_F10_S262_comb 0.000000        0.000000        0.00000        \n",
       "HNSCC17_P4_D04_S136_comb  0.067639        0.032806        4.04410        \n",
       "HNSCC20_P13_C06_S222_comb 0.182690        0.231430        0.00000        \n",
       "HNSCC20_P13_C12_S228_comb 0.000000        0.718960        2.78470        \n",
       "HNSCC17_P4_H04_S184_comb  0.000000        0.000000        0.63506        \n",
       "HNSCC17_P4_C06_S126_comb  0.000000        0.000000        2.11300        \n",
       "HNSCC20_P3_D01_S37_comb   0.078610        0.092207        3.20070        \n",
       "HNSCC20_P3_D09_S45_comb   0.107020        0.000000        0.00000        \n",
       "HNSCC17_P4_E06_S150_comb  0.132250        0.000000        3.74010        \n",
       "HNSCC20_P13_H10_S286_comb 1.006500        0.056584        0.00000        \n",
       "HNSCC17_P4_A02_S98_comb   0.147960        0.149260        4.10650        \n",
       "HNSCC20_P13_D01_S229_comb 0.000000        0.000000        0.00000        \n",
       "HNSCC20_P13_G02_S266_comb 0.246100        0.109690        0.00000        \n",
       "HNSCC17_P4_B04_S112_comb  0.053806        0.107020        0.94785        \n",
       "HNSCC17_P4_C09_S129_comb  0.055196        0.066261        4.27180        \n",
       "HNSCC20_P13_A12_S204_comb 0.000000        0.000000        0.19409        \n",
       "HNSCC17_P4_F06_S162_comb  0.116360        0.117700        0.00000        \n",
       "HNSCC20_P3_B10_S22_comb   0.000000        0.737250        3.38280        \n",
       "HNSCC20_P13_B11_S215_comb 0.201630        0.000000        1.00070        \n",
       "HNSCC20_P3_C08_S32_comb   0.000000        0.000000        2.52430        \n",
       "HNSCC17_P4_H03_S183_comb  0.000000        0.037031        0.00000        \n",
       "HNSCC20_P3_F09_S69_comb   0.000000        0.039840        0.67717        \n",
       "HNSCC17_P4_G12_S180_comb  0.398350        0.254590        0.75275        \n",
       "HNSCC20_P13_C05_S221_comb 0.746740        0.318460        0.00000        \n",
       "HNSCC17_P4_C12_S132_comb  0.000000        2.106300        4.05570        \n",
       "HNSCC20_P3_H08_S92_comb   0.236340        0.291600        3.73420        \n",
       "HNSCC20_P3_G06_S78_comb   0.000000        0.111030        0.00000        \n",
       "                          ENSG00000074755 ENSG00000036549\n",
       "HN28_P15_D06_S330_comb    0.000000        0.00000        \n",
       "HN28_P6_G05_S173_comb     3.771600        0.00000        \n",
       "HN26_P14_D11_S239_comb    1.304500        2.11200        \n",
       "HN26_P14_H05_S281_comb    0.093560        0.00000        \n",
       "HN26_P25_H09_S189_comb    0.000000        0.00000        \n",
       "HN26_P14_H06_S282_comb    0.000000        0.00000        \n",
       "HN25_P25_C04_S316_comb    0.856790        0.00000        \n",
       "HN26_P25_A11_S107_comb    0.000000        0.00000        \n",
       "HN26_P25_C09_S129_comb    0.017209        0.00000        \n",
       "HNSCC26_P24_H05_S377_comb 0.000000        0.00000        \n",
       "HN25_P5_E10_S58_comb      0.000000        0.00000        \n",
       "HN25_P24_B02_S110_comb    0.236340        0.44679        \n",
       "HN25_P25_C01_S313_comb    0.000000        0.00000        \n",
       "HN28_P15_G06_S366_comb    0.000000        0.00000        \n",
       "HN26_P6_B06_S18_comb      0.000000        0.00000        \n",
       "HN25_P5_C05_S29_comb      0.000000        0.00000        \n",
       "HN28_P6_D09_S141_comb     0.000000        0.00000        \n",
       "HN26_P5_H01_S85_comb      0.000000        0.00000        \n",
       "HN26_P13_D07_S139_comb    0.000000        0.00000        \n",
       "HN26_P5_E06_S54_comb      0.000000        3.05260        \n",
       "HN26_P26_H05_S377_comb    0.017209        2.39230        \n",
       "HNSCC26_P24_F12_S360_comb 0.000000        0.00000        \n",
       "HNSCC26_P24_F03_S351_comb 0.000000        0.00000        \n",
       "HN26_P6_D08_S44_comb      1.202900        0.00000        \n",
       "HN25_P5_E12_S60_comb      1.488500        0.00000        \n",
       "HNSCC26_P24_C01_S313_comb 1.371800        1.93050        \n",
       "HN25_P5_F01_S61_comb      0.000000        0.00000        \n",
       "HN26_P5_D12_S48_comb      0.000000        0.00000        \n",
       "HN25_P25_C11_S323_comb    0.200380        0.00000        \n",
       "HN25_P25_B12_S312_comb    1.390100        0.00000        \n",
       "⋮                         ⋮               ⋮              \n",
       "HNSCC17_P4_A08_S104_comb  0.025738        1.335700       \n",
       "HNSCC17_P4_E10_S154_comb  0.000000        0.000000       \n",
       "HNSCC17_P4_E02_S146_comb  0.000000        0.000000       \n",
       "HNSCC20_P13_F10_S262_comb 0.000000        3.520300       \n",
       "HNSCC17_P4_D04_S136_comb  0.505890        0.000000       \n",
       "HNSCC20_P13_C06_S222_comb 1.938100        3.675800       \n",
       "HNSCC20_P13_C12_S228_comb 0.000000        0.000000       \n",
       "HNSCC17_P4_H04_S184_comb  0.000000        0.000000       \n",
       "HNSCC17_P4_C06_S126_comb  0.000000        0.530070       \n",
       "HNSCC20_P3_D01_S37_comb   0.000000        0.000000       \n",
       "HNSCC20_P3_D09_S45_comb   0.000000        2.838800       \n",
       "HNSCC17_P4_E06_S150_comb  0.000000        0.000000       \n",
       "HNSCC20_P13_H10_S286_comb 0.000000        3.643400       \n",
       "HNSCC17_P4_A02_S98_comb   0.000000        0.000000       \n",
       "HNSCC20_P13_D01_S229_comb 1.423300        0.000000       \n",
       "HNSCC20_P13_G02_S266_comb 0.000000        0.000000       \n",
       "HNSCC17_P4_B04_S112_comb  0.000000        0.000000       \n",
       "HNSCC17_P4_C09_S129_comb  0.000000        0.000000       \n",
       "HNSCC20_P13_A12_S204_comb 1.190900        1.174400       \n",
       "HNSCC17_P4_F06_S162_comb  0.000000        0.000000       \n",
       "HNSCC20_P3_B10_S22_comb   0.107020        2.233300       \n",
       "HNSCC20_P13_B11_S215_comb 0.575310        1.680800       \n",
       "HNSCC20_P3_C08_S32_comb   0.172490        0.000000       \n",
       "HNSCC17_P4_H03_S183_comb  0.000000        0.000000       \n",
       "HNSCC20_P3_F09_S69_comb   1.017900        0.071763       \n",
       "HNSCC17_P4_G12_S180_comb  0.000000        0.000000       \n",
       "HNSCC20_P13_C05_S221_comb 0.000000        0.000000       \n",
       "HNSCC17_P4_C12_S132_comb  0.000000        0.000000       \n",
       "HNSCC20_P3_H08_S92_comb   0.000000        0.000000       \n",
       "HNSCC20_P3_G06_S78_comb   0.000000        0.000000       "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "ref.data.filtered"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 51,
   "id": "27dd1865",
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A data.frame: 5902 × 2</caption>\n",
       "<thead>\n",
       "\t<tr><th scope=col>X</th><th scope=col>cell_category</th></tr>\n",
       "\t<tr><th scope=col>&lt;chr&gt;</th><th scope=col>&lt;chr&gt;</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><td>HN28_P15_D06_S330_comb   </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN28_P6_G05_S173_comb    </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN26_P14_D11_S239_comb   </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN26_P14_H05_S281_comb   </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN26_P25_H09_S189_comb   </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN26_P14_H06_S282_comb   </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN25_P25_C04_S316_comb   </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN26_P25_A11_S107_comb   </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN26_P25_C09_S129_comb   </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HNSCC26_P24_H05_S377_comb</td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN25_P5_E10_S58_comb     </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN25_P24_B02_S110_comb   </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN25_P25_C01_S313_comb   </td><td>B cell    </td></tr>\n",
       "\t<tr><td>HN28_P15_G06_S366_comb   </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN26_P6_B06_S18_comb     </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN25_P5_C05_S29_comb     </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN28_P6_D09_S141_comb    </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN26_P5_H01_S85_comb     </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN26_P13_D07_S139_comb   </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN26_P5_E06_S54_comb     </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN26_P26_H05_S377_comb   </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HNSCC26_P24_F12_S360_comb</td><td>tumor     </td></tr>\n",
       "\t<tr><td>HNSCC26_P24_F03_S351_comb</td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN26_P6_D08_S44_comb     </td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN25_P5_E12_S60_comb     </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HNSCC26_P24_C01_S313_comb</td><td>tumor     </td></tr>\n",
       "\t<tr><td>HN25_P5_F01_S61_comb     </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN26_P5_D12_S48_comb     </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN25_P25_C11_S323_comb   </td><td>Fibroblast</td></tr>\n",
       "\t<tr><td>HN25_P25_B12_S312_comb   </td><td>tumor     </td></tr>\n",
       "\t<tr><td>⋮</td><td>⋮</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_A08_S104_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_E10_S154_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_E02_S146_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P13_F10_S262_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_D04_S136_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P13_C06_S222_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P13_C12_S228_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_H04_S184_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_C06_S126_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P3_D01_S37_comb  </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P3_D09_S45_comb  </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_E06_S150_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P13_H10_S286_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_A02_S98_comb  </td><td>NA   </td></tr>\n",
       "\t<tr><td>HNSCC20_P13_D01_S229_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P13_G02_S266_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_B04_S112_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_C09_S129_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P13_A12_S204_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_F06_S162_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P3_B10_S22_comb  </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P13_B11_S215_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P3_C08_S32_comb  </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_H03_S183_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P3_F09_S69_comb  </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_G12_S180_comb </td><td>NA   </td></tr>\n",
       "\t<tr><td>HNSCC20_P13_C05_S221_comb</td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC17_P4_C12_S132_comb </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P3_H08_S92_comb  </td><td>tumor</td></tr>\n",
       "\t<tr><td>HNSCC20_P3_G06_S78_comb  </td><td>tumor</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A data.frame: 5902 × 2\n",
       "\\begin{tabular}{ll}\n",
       " X & cell\\_category\\\\\n",
       " <chr> & <chr>\\\\\n",
       "\\hline\n",
       "\t HN28\\_P15\\_D06\\_S330\\_comb    & Fibroblast\\\\\n",
       "\t HN28\\_P6\\_G05\\_S173\\_comb     & Fibroblast\\\\\n",
       "\t HN26\\_P14\\_D11\\_S239\\_comb    & tumor     \\\\\n",
       "\t HN26\\_P14\\_H05\\_S281\\_comb    & Fibroblast\\\\\n",
       "\t HN26\\_P25\\_H09\\_S189\\_comb    & tumor     \\\\\n",
       "\t HN26\\_P14\\_H06\\_S282\\_comb    & tumor     \\\\\n",
       "\t HN25\\_P25\\_C04\\_S316\\_comb    & tumor     \\\\\n",
       "\t HN26\\_P25\\_A11\\_S107\\_comb    & Fibroblast\\\\\n",
       "\t HN26\\_P25\\_C09\\_S129\\_comb    & tumor     \\\\\n",
       "\t HNSCC26\\_P24\\_H05\\_S377\\_comb & tumor     \\\\\n",
       "\t HN25\\_P5\\_E10\\_S58\\_comb      & Fibroblast\\\\\n",
       "\t HN25\\_P24\\_B02\\_S110\\_comb    & tumor     \\\\\n",
       "\t HN25\\_P25\\_C01\\_S313\\_comb    & B cell    \\\\\n",
       "\t HN28\\_P15\\_G06\\_S366\\_comb    & Fibroblast\\\\\n",
       "\t HN26\\_P6\\_B06\\_S18\\_comb      & Fibroblast\\\\\n",
       "\t HN25\\_P5\\_C05\\_S29\\_comb      & Fibroblast\\\\\n",
       "\t HN28\\_P6\\_D09\\_S141\\_comb     & Fibroblast\\\\\n",
       "\t HN26\\_P5\\_H01\\_S85\\_comb      & tumor     \\\\\n",
       "\t HN26\\_P13\\_D07\\_S139\\_comb    & Fibroblast\\\\\n",
       "\t HN26\\_P5\\_E06\\_S54\\_comb      & tumor     \\\\\n",
       "\t HN26\\_P26\\_H05\\_S377\\_comb    & tumor     \\\\\n",
       "\t HNSCC26\\_P24\\_F12\\_S360\\_comb & tumor     \\\\\n",
       "\t HNSCC26\\_P24\\_F03\\_S351\\_comb & tumor     \\\\\n",
       "\t HN26\\_P6\\_D08\\_S44\\_comb      & tumor     \\\\\n",
       "\t HN25\\_P5\\_E12\\_S60\\_comb      & Fibroblast\\\\\n",
       "\t HNSCC26\\_P24\\_C01\\_S313\\_comb & tumor     \\\\\n",
       "\t HN25\\_P5\\_F01\\_S61\\_comb      & Fibroblast\\\\\n",
       "\t HN26\\_P5\\_D12\\_S48\\_comb      & Fibroblast\\\\\n",
       "\t HN25\\_P25\\_C11\\_S323\\_comb    & Fibroblast\\\\\n",
       "\t HN25\\_P25\\_B12\\_S312\\_comb    & tumor     \\\\\n",
       "\t ⋮ & ⋮\\\\\n",
       "\t HNSCC17\\_P4\\_A08\\_S104\\_comb  & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_E10\\_S154\\_comb  & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_E02\\_S146\\_comb  & tumor\\\\\n",
       "\t HNSCC20\\_P13\\_F10\\_S262\\_comb & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_D04\\_S136\\_comb  & tumor\\\\\n",
       "\t HNSCC20\\_P13\\_C06\\_S222\\_comb & tumor\\\\\n",
       "\t HNSCC20\\_P13\\_C12\\_S228\\_comb & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_H04\\_S184\\_comb  & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_C06\\_S126\\_comb  & tumor\\\\\n",
       "\t HNSCC20\\_P3\\_D01\\_S37\\_comb   & tumor\\\\\n",
       "\t HNSCC20\\_P3\\_D09\\_S45\\_comb   & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_E06\\_S150\\_comb  & tumor\\\\\n",
       "\t HNSCC20\\_P13\\_H10\\_S286\\_comb & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_A02\\_S98\\_comb   & NA   \\\\\n",
       "\t HNSCC20\\_P13\\_D01\\_S229\\_comb & tumor\\\\\n",
       "\t HNSCC20\\_P13\\_G02\\_S266\\_comb & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_B04\\_S112\\_comb  & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_C09\\_S129\\_comb  & tumor\\\\\n",
       "\t HNSCC20\\_P13\\_A12\\_S204\\_comb & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_F06\\_S162\\_comb  & tumor\\\\\n",
       "\t HNSCC20\\_P3\\_B10\\_S22\\_comb   & tumor\\\\\n",
       "\t HNSCC20\\_P13\\_B11\\_S215\\_comb & tumor\\\\\n",
       "\t HNSCC20\\_P3\\_C08\\_S32\\_comb   & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_H03\\_S183\\_comb  & tumor\\\\\n",
       "\t HNSCC20\\_P3\\_F09\\_S69\\_comb   & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_G12\\_S180\\_comb  & NA   \\\\\n",
       "\t HNSCC20\\_P13\\_C05\\_S221\\_comb & tumor\\\\\n",
       "\t HNSCC17\\_P4\\_C12\\_S132\\_comb  & tumor\\\\\n",
       "\t HNSCC20\\_P3\\_H08\\_S92\\_comb   & tumor\\\\\n",
       "\t HNSCC20\\_P3\\_G06\\_S78\\_comb   & tumor\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A data.frame: 5902 × 2\n",
       "\n",
       "| X &lt;chr&gt; | cell_category &lt;chr&gt; |\n",
       "|---|---|\n",
       "| HN28_P15_D06_S330_comb    | Fibroblast |\n",
       "| HN28_P6_G05_S173_comb     | Fibroblast |\n",
       "| HN26_P14_D11_S239_comb    | tumor      |\n",
       "| HN26_P14_H05_S281_comb    | Fibroblast |\n",
       "| HN26_P25_H09_S189_comb    | tumor      |\n",
       "| HN26_P14_H06_S282_comb    | tumor      |\n",
       "| HN25_P25_C04_S316_comb    | tumor      |\n",
       "| HN26_P25_A11_S107_comb    | Fibroblast |\n",
       "| HN26_P25_C09_S129_comb    | tumor      |\n",
       "| HNSCC26_P24_H05_S377_comb | tumor      |\n",
       "| HN25_P5_E10_S58_comb      | Fibroblast |\n",
       "| HN25_P24_B02_S110_comb    | tumor      |\n",
       "| HN25_P25_C01_S313_comb    | B cell     |\n",
       "| HN28_P15_G06_S366_comb    | Fibroblast |\n",
       "| HN26_P6_B06_S18_comb      | Fibroblast |\n",
       "| HN25_P5_C05_S29_comb      | Fibroblast |\n",
       "| HN28_P6_D09_S141_comb     | Fibroblast |\n",
       "| HN26_P5_H01_S85_comb      | tumor      |\n",
       "| HN26_P13_D07_S139_comb    | Fibroblast |\n",
       "| HN26_P5_E06_S54_comb      | tumor      |\n",
       "| HN26_P26_H05_S377_comb    | tumor      |\n",
       "| HNSCC26_P24_F12_S360_comb | tumor      |\n",
       "| HNSCC26_P24_F03_S351_comb | tumor      |\n",
       "| HN26_P6_D08_S44_comb      | tumor      |\n",
       "| HN25_P5_E12_S60_comb      | Fibroblast |\n",
       "| HNSCC26_P24_C01_S313_comb | tumor      |\n",
       "| HN25_P5_F01_S61_comb      | Fibroblast |\n",
       "| HN26_P5_D12_S48_comb      | Fibroblast |\n",
       "| HN25_P25_C11_S323_comb    | Fibroblast |\n",
       "| HN25_P25_B12_S312_comb    | tumor      |\n",
       "| ⋮ | ⋮ |\n",
       "| HNSCC17_P4_A08_S104_comb  | tumor |\n",
       "| HNSCC17_P4_E10_S154_comb  | tumor |\n",
       "| HNSCC17_P4_E02_S146_comb  | tumor |\n",
       "| HNSCC20_P13_F10_S262_comb | tumor |\n",
       "| HNSCC17_P4_D04_S136_comb  | tumor |\n",
       "| HNSCC20_P13_C06_S222_comb | tumor |\n",
       "| HNSCC20_P13_C12_S228_comb | tumor |\n",
       "| HNSCC17_P4_H04_S184_comb  | tumor |\n",
       "| HNSCC17_P4_C06_S126_comb  | tumor |\n",
       "| HNSCC20_P3_D01_S37_comb   | tumor |\n",
       "| HNSCC20_P3_D09_S45_comb   | tumor |\n",
       "| HNSCC17_P4_E06_S150_comb  | tumor |\n",
       "| HNSCC20_P13_H10_S286_comb | tumor |\n",
       "| HNSCC17_P4_A02_S98_comb   | NA    |\n",
       "| HNSCC20_P13_D01_S229_comb | tumor |\n",
       "| HNSCC20_P13_G02_S266_comb | tumor |\n",
       "| HNSCC17_P4_B04_S112_comb  | tumor |\n",
       "| HNSCC17_P4_C09_S129_comb  | tumor |\n",
       "| HNSCC20_P13_A12_S204_comb | tumor |\n",
       "| HNSCC17_P4_F06_S162_comb  | tumor |\n",
       "| HNSCC20_P3_B10_S22_comb   | tumor |\n",
       "| HNSCC20_P13_B11_S215_comb | tumor |\n",
       "| HNSCC20_P3_C08_S32_comb   | tumor |\n",
       "| HNSCC17_P4_H03_S183_comb  | tumor |\n",
       "| HNSCC20_P3_F09_S69_comb   | tumor |\n",
       "| HNSCC17_P4_G12_S180_comb  | NA    |\n",
       "| HNSCC20_P13_C05_S221_comb | tumor |\n",
       "| HNSCC17_P4_C12_S132_comb  | tumor |\n",
       "| HNSCC20_P3_H08_S92_comb   | tumor |\n",
       "| HNSCC20_P3_G06_S78_comb   | tumor |\n",
       "\n"
      ],
      "text/plain": [
       "     X                         cell_category\n",
       "1    HN28_P15_D06_S330_comb    Fibroblast   \n",
       "2    HN28_P6_G05_S173_comb     Fibroblast   \n",
       "3    HN26_P14_D11_S239_comb    tumor        \n",
       "4    HN26_P14_H05_S281_comb    Fibroblast   \n",
       "5    HN26_P25_H09_S189_comb    tumor        \n",
       "6    HN26_P14_H06_S282_comb    tumor        \n",
       "7    HN25_P25_C04_S316_comb    tumor        \n",
       "8    HN26_P25_A11_S107_comb    Fibroblast   \n",
       "9    HN26_P25_C09_S129_comb    tumor        \n",
       "10   HNSCC26_P24_H05_S377_comb tumor        \n",
       "11   HN25_P5_E10_S58_comb      Fibroblast   \n",
       "12   HN25_P24_B02_S110_comb    tumor        \n",
       "13   HN25_P25_C01_S313_comb    B cell       \n",
       "14   HN28_P15_G06_S366_comb    Fibroblast   \n",
       "15   HN26_P6_B06_S18_comb      Fibroblast   \n",
       "16   HN25_P5_C05_S29_comb      Fibroblast   \n",
       "17   HN28_P6_D09_S141_comb     Fibroblast   \n",
       "18   HN26_P5_H01_S85_comb      tumor        \n",
       "19   HN26_P13_D07_S139_comb    Fibroblast   \n",
       "20   HN26_P5_E06_S54_comb      tumor        \n",
       "21   HN26_P26_H05_S377_comb    tumor        \n",
       "22   HNSCC26_P24_F12_S360_comb tumor        \n",
       "23   HNSCC26_P24_F03_S351_comb tumor        \n",
       "24   HN26_P6_D08_S44_comb      tumor        \n",
       "25   HN25_P5_E12_S60_comb      Fibroblast   \n",
       "26   HNSCC26_P24_C01_S313_comb tumor        \n",
       "27   HN25_P5_F01_S61_comb      Fibroblast   \n",
       "28   HN26_P5_D12_S48_comb      Fibroblast   \n",
       "29   HN25_P25_C11_S323_comb    Fibroblast   \n",
       "30   HN25_P25_B12_S312_comb    tumor        \n",
       "⋮    ⋮                         ⋮            \n",
       "5873 HNSCC17_P4_A08_S104_comb  tumor        \n",
       "5874 HNSCC17_P4_E10_S154_comb  tumor        \n",
       "5875 HNSCC17_P4_E02_S146_comb  tumor        \n",
       "5876 HNSCC20_P13_F10_S262_comb tumor        \n",
       "5877 HNSCC17_P4_D04_S136_comb  tumor        \n",
       "5878 HNSCC20_P13_C06_S222_comb tumor        \n",
       "5879 HNSCC20_P13_C12_S228_comb tumor        \n",
       "5880 HNSCC17_P4_H04_S184_comb  tumor        \n",
       "5881 HNSCC17_P4_C06_S126_comb  tumor        \n",
       "5882 HNSCC20_P3_D01_S37_comb   tumor        \n",
       "5883 HNSCC20_P3_D09_S45_comb   tumor        \n",
       "5884 HNSCC17_P4_E06_S150_comb  tumor        \n",
       "5885 HNSCC20_P13_H10_S286_comb tumor        \n",
       "5886 HNSCC17_P4_A02_S98_comb   NA           \n",
       "5887 HNSCC20_P13_D01_S229_comb tumor        \n",
       "5888 HNSCC20_P13_G02_S266_comb tumor        \n",
       "5889 HNSCC17_P4_B04_S112_comb  tumor        \n",
       "5890 HNSCC17_P4_C09_S129_comb  tumor        \n",
       "5891 HNSCC20_P13_A12_S204_comb tumor        \n",
       "5892 HNSCC17_P4_F06_S162_comb  tumor        \n",
       "5893 HNSCC20_P3_B10_S22_comb   tumor        \n",
       "5894 HNSCC20_P13_B11_S215_comb tumor        \n",
       "5895 HNSCC20_P3_C08_S32_comb   tumor        \n",
       "5896 HNSCC17_P4_H03_S183_comb  tumor        \n",
       "5897 HNSCC20_P3_F09_S69_comb   tumor        \n",
       "5898 HNSCC17_P4_G12_S180_comb  NA           \n",
       "5899 HNSCC20_P13_C05_S221_comb tumor        \n",
       "5900 HNSCC17_P4_C12_S132_comb  tumor        \n",
       "5901 HNSCC20_P3_H08_S92_comb   tumor        \n",
       "5902 HNSCC20_P3_G06_S78_comb   tumor        "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "label"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 127,
   "id": "b33b824a",
   "metadata": {},
   "outputs": [],
   "source": [
    "# ?run.Ted"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 52,
   "id": "77bb9c43",
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "[1] \"removing non-numeric genes...\"\n",
      "[1] \"removing outlier genes...\"\n",
      "Number of outlier genes filtered= 7 \n",
      "[1] \"aligning reference and mixture...\"\n",
      "[1] \"Warning: NA found in the cell (sub)type labels. These cells will be excluded!\"\n",
      "[1] \"Warning: NA found in the cell (sub)type labels. These cells will be excluded!\"\n",
      "[1] \"run first sampling\"\n",
      "Start run... This may take a while \n",
      "R Version:  R version 4.1.3 (2022-03-10) \n",
      "\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "snowfall 1.84-6.1 initialized (using snow 0.4-4): parallel execution on 12 CPUs.\n",
      "\n",
      "\n",
      "\n",
      "Stopping cluster\n",
      "\n",
      "\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "[1] \"merge subtypes\"\n",
      "        Fibroblast tumor B cell myocyte Macrophage Endothelial T cell Dendritic\n",
      "Min.         0.000 0.003  0.000   0.000      0.000       0.000  0.000     0.000\n",
      "1st Qu.      0.047 0.618  0.000   0.000      0.007       0.009  0.000     0.000\n",
      "Median       0.129 0.767  0.000   0.000      0.017       0.021  0.001     0.000\n",
      "Mean         0.164 0.732  0.002   0.026      0.032       0.032  0.006     0.003\n",
      "3rd Qu.      0.240 0.882  0.000   0.012      0.045       0.041  0.005     0.000\n",
      "Max.         0.958 0.998  0.053   0.785      0.287       0.406  0.126     0.090\n",
      "         Mast\n",
      "Min.    0.000\n",
      "1st Qu. 0.000\n",
      "Median  0.000\n",
      "Mean    0.004\n",
      "3rd Qu. 0.002\n",
      "Max.    0.129\n",
      "[1] \"pooling information across samples\"\n",
      "Start optimization... This may take a while \n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "snowfall 1.84-6.1 initialized (using snow 0.4-4): parallel execution on 12 CPUs.\n",
      "\n",
      "\n",
      "\n",
      "Stopping cluster\n",
      "\n",
      "\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "[1] \"run final sampling\"\n",
      "Start run... This may take a while \n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "snowfall 1.84-6.1 initialized (using snow 0.4-4): parallel execution on 12 CPUs.\n",
      "\n",
      "\n",
      "\n",
      "Stopping cluster\n",
      "\n",
      "\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "        tumor Fibroblast B cell myocyte Macrophage Endothelial T cell Dendritic\n",
      "Min.    0.072      0.000  0.000   0.000      0.000       0.000  0.000     0.000\n",
      "1st Qu. 0.726      0.022  0.000   0.000      0.005       0.003  0.000     0.000\n",
      "Median  0.851      0.074  0.000   0.000      0.013       0.009  0.000     0.000\n",
      "Mean    0.805      0.121  0.002   0.021      0.025       0.016  0.004     0.004\n",
      "3rd Qu. 0.928      0.169  0.001   0.006      0.034       0.021  0.004     0.000\n",
      "Max.    0.999      0.862  0.046   0.799      0.223       0.186  0.075     0.111\n",
      "         Mast\n",
      "Min.    0.000\n",
      "1st Qu. 0.000\n",
      "Median  0.000\n",
      "Mean    0.002\n",
      "3rd Qu. 0.000\n",
      "Max.    0.099\n",
      "[1] \"vst transformation is feasible\"\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "converting counts to integer mode\n",
      "\n"
     ]
    }
   ],
   "source": [
    "#run BayesPrism main func\n",
    "res <- run.Ted(ref.dat=ref.data.filtered, X=df_TCGA_t,cell.type.labels=label$cell_category,\n",
    "               tum.key='tumor',input.type=\"scRNA\",n.cores=12,pdf.name=\"PuramTCGA\",seed=52322)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 54,
   "id": "9c4682f3",
   "metadata": {},
   "outputs": [],
   "source": [
    "saveRDS(res,\"/home/cke/BayesPrism/BP_PuramTCGA_res.rds\")"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "1e57257f",
   "metadata": {},
   "source": [
    "### A list of result is returned in this function.\n",
    "\n",
    "para\t\n",
    "All input data and parameters.\n",
    "\n",
    "res\t\n",
    "All output of TED.\n",
    "\n",
    "res$first.gibbs.res$gibbs.theta\t\n",
    "Initial estimates of fraction for all cell subtypes in each bulk sample.\n",
    "\n",
    "res$first.gibbs.res$Znkg\t\n",
    "Initial estimates of the mean of posterior read count for each cell subtypes in each bulk sample.\n",
    "\n",
    "res$first.gibbs.res$theta.merged\t\n",
    "Initial estimates of fraction summed across cell types in each bulk sample.\n",
    "\n",
    "res$first.gibbs.res$Znkg.merged\t\n",
    "Initial estimates of the mean of posterior read count summed across cell types in each bulk sample.\n",
    "\n",
    "res$Zkg.tum\t\n",
    "Mean of posterior of gene expression of tumor in each patient.\n",
    "\n",
    "res$Zkg.tum.norm\t\n",
    "Depth normalized Zkg.tum (A pseudo count is added, such that the zero-valued genes have the same value as the min(phi.input)). Refered to as the psi.tum in the TED paper)\n",
    "\n",
    "res$Zkg.tum.vst\t\n",
    "Variance stablized transformed value of Zkg.tum. If vst transformation is not feasible, return NULL.\n",
    "\n",
    "res$phi.env\t\n",
    "Batch effect corrected expression profiles of stromal cells (refered to as the psi.str in the TED paper)\n",
    "\n",
    "res$final.gibbs.theta\t\n",
    "Updated theta after batch correction and tumor expression estimates.\n",
    "\n",
    "res$cor.mat\t\n",
    "The correlation matrix of the estimated tumor expression profiles across bulk RNA-seq samples."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 61,
   "id": "ac92bbf4",
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A matrix: 546 × 9 of type dbl</caption>\n",
       "<thead>\n",
       "\t<tr><th></th><th scope=col>tumor</th><th scope=col>Fibroblast</th><th scope=col>B cell</th><th scope=col>myocyte</th><th scope=col>Macrophage</th><th scope=col>Endothelial</th><th scope=col>T cell</th><th scope=col>Dendritic</th><th scope=col>Mast</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><th scope=row>TCGA.BB.4224.01A</th><td>0.8953963</td><td>3.295279e-03</td><td>1.535432e-07</td><td>2.076378e-03</td><td>2.663471e-06</td><td>1.099243e-06</td><td>2.711799e-07</td><td>4.547351e-07</td><td>9.922738e-02</td></tr>\n",
       "\t<tr><th scope=row>TCGA.H7.7774.01A</th><td>0.9807876</td><td>9.213523e-07</td><td>1.956431e-06</td><td>1.582816e-07</td><td>1.186069e-02</td><td>7.062818e-07</td><td>1.267113e-04</td><td>1.133469e-06</td><td>7.220150e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6943.01A</th><td>0.5239461</td><td>3.799039e-01</td><td>1.548700e-03</td><td>2.208963e-07</td><td>7.545321e-02</td><td>8.543457e-03</td><td>1.060355e-02</td><td>3.213430e-07</td><td>5.962804e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.5374.01A</th><td>0.8727039</td><td>2.463040e-02</td><td>6.619988e-03</td><td>6.413547e-03</td><td>2.021994e-02</td><td>2.152436e-02</td><td>2.999286e-02</td><td>1.789418e-02</td><td>8.044354e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.6227.01A</th><td>0.6538779</td><td>2.342006e-01</td><td>1.996756e-07</td><td>7.141557e-02</td><td>7.623701e-03</td><td>3.287952e-02</td><td>3.276224e-07</td><td>4.224889e-07</td><td>1.701781e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6959.01A</th><td>0.7848157</td><td>9.008879e-02</td><td>3.630708e-05</td><td>6.450137e-02</td><td>2.570535e-02</td><td>3.484607e-02</td><td>6.940279e-07</td><td>4.514340e-06</td><td>1.185480e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.F7.A61V.01A</th><td>0.9545372</td><td>1.147164e-02</td><td>1.391773e-03</td><td>2.241424e-02</td><td>4.397206e-03</td><td>5.219229e-03</td><td>5.633430e-04</td><td>4.516596e-06</td><td>8.426878e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7413.01A</th><td>0.7576784</td><td>2.165254e-01</td><td>1.947499e-07</td><td>8.478491e-08</td><td>2.579297e-02</td><td>4.341206e-07</td><td>1.038621e-06</td><td>2.309817e-07</td><td>1.216114e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7247.01A</th><td>0.7911627</td><td>1.108126e-01</td><td>1.374201e-07</td><td>7.858550e-02</td><td>6.057291e-07</td><td>1.943738e-02</td><td>1.658183e-07</td><td>6.054190e-07</td><td>2.752071e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.5249.01A</th><td>0.8287251</td><td>5.001096e-02</td><td>7.550117e-03</td><td>1.137713e-07</td><td>2.663733e-02</td><td>3.129438e-02</td><td>3.085065e-02</td><td>2.493104e-02</td><td>3.331009e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.5331.01A</th><td>0.8679074</td><td>3.680547e-02</td><td>6.729025e-04</td><td>6.492139e-08</td><td>6.722354e-02</td><td>2.205727e-02</td><td>5.329257e-03</td><td>3.620704e-06</td><td>4.945356e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.BB.8601.01A</th><td>0.9933812</td><td>4.261229e-03</td><td>7.357805e-05</td><td>2.507918e-07</td><td>3.730104e-06</td><td>2.237834e-03</td><td>1.768300e-06</td><td>2.015228e-06</td><td>3.842106e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45W.01A</th><td>0.7583385</td><td>9.038100e-02</td><td>4.573747e-02</td><td>2.842859e-07</td><td>5.930226e-02</td><td>3.803786e-02</td><td>5.694007e-03</td><td>2.508070e-03</td><td>5.767332e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.7063.01A</th><td>0.8932472</td><td>2.143019e-02</td><td>2.929627e-07</td><td>2.839658e-07</td><td>6.462695e-02</td><td>1.244862e-02</td><td>6.942133e-03</td><td>4.127833e-05</td><td>1.263061e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.5373.01A</th><td>0.7648254</td><td>1.857341e-01</td><td>3.306371e-07</td><td>6.088100e-04</td><td>2.179955e-02</td><td>4.760714e-06</td><td>7.257815e-07</td><td>8.311730e-07</td><td>2.702557e-02</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45T.01A</th><td>0.8189485</td><td>5.773553e-02</td><td>5.785000e-03</td><td>1.473200e-02</td><td>6.505784e-02</td><td>1.423510e-02</td><td>1.939667e-02</td><td>9.113431e-05</td><td>4.018240e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.HD.A4C1.01A</th><td>0.9037093</td><td>8.132439e-02</td><td>7.313362e-07</td><td>1.059151e-07</td><td>4.587139e-03</td><td>1.037395e-02</td><td>1.168693e-06</td><td>1.853892e-06</td><td>1.389217e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7438.11A</th><td>0.9736846</td><td>2.405088e-03</td><td>6.825740e-04</td><td>2.766721e-03</td><td>1.248155e-02</td><td>1.094154e-03</td><td>6.450133e-03</td><td>1.981943e-04</td><td>2.369504e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.5444.01A</th><td>0.4018990</td><td>5.008603e-01</td><td>1.421520e-07</td><td>3.634083e-02</td><td>5.472763e-02</td><td>6.170893e-03</td><td>4.490983e-07</td><td>4.175766e-07</td><td>2.911519e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.BA.5556.01A</th><td>0.8490606</td><td>4.796692e-02</td><td>2.149780e-05</td><td>9.793571e-08</td><td>5.747951e-02</td><td>2.534477e-02</td><td>1.919881e-02</td><td>9.241382e-04</td><td>3.625550e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.P3.A6SX.01A</th><td>0.8960362</td><td>9.110862e-02</td><td>1.878011e-07</td><td>1.098512e-02</td><td>6.988049e-07</td><td>1.867874e-03</td><td>4.670143e-07</td><td>3.429470e-07</td><td>5.174869e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7242.11A</th><td>0.9755767</td><td>5.311162e-03</td><td>3.153993e-05</td><td>3.141680e-07</td><td>1.229840e-02</td><td>4.594129e-03</td><td>2.158675e-03</td><td>2.730977e-05</td><td>1.801851e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.DQ.7592.01A</th><td>0.8323528</td><td>1.342008e-01</td><td>1.722611e-07</td><td>1.280968e-02</td><td>1.281682e-02</td><td>5.765994e-03</td><td>9.210478e-04</td><td>8.855847e-07</td><td>1.131870e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6937.01A</th><td>0.8360634</td><td>1.441721e-01</td><td>3.585737e-07</td><td>4.275409e-07</td><td>1.778293e-02</td><td>1.976317e-03</td><td>7.544563e-07</td><td>3.166395e-06</td><td>5.797741e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.QK.A8ZB.01A</th><td>0.8499897</td><td>1.257516e-01</td><td>6.130647e-03</td><td>1.031490e-07</td><td>6.951394e-03</td><td>7.469520e-03</td><td>5.701797e-07</td><td>1.859023e-06</td><td>3.704592e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7432.01A</th><td>0.9688731</td><td>2.165490e-02</td><td>1.442955e-07</td><td>1.739435e-07</td><td>4.331192e-03</td><td>5.137664e-03</td><td>3.056553e-07</td><td>1.084470e-06</td><td>1.401741e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7089.01A</th><td>0.9668070</td><td>8.355609e-03</td><td>2.990496e-07</td><td>1.403883e-07</td><td>8.618054e-03</td><td>1.516107e-02</td><td>1.011682e-03</td><td>6.487607e-06</td><td>3.969543e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6939.11A</th><td>0.3108183</td><td>2.925750e-02</td><td>1.597606e-03</td><td>6.230553e-01</td><td>1.509185e-03</td><td>3.375961e-02</td><td>2.043617e-06</td><td>2.373454e-07</td><td>1.717001e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.BA.4075.01A</th><td>0.9198085</td><td>4.745561e-02</td><td>3.472322e-07</td><td>2.176400e-03</td><td>2.556290e-02</td><td>4.994196e-03</td><td>7.253185e-07</td><td>9.011630e-07</td><td>4.677923e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.T3.A92M.01A</th><td>0.6663292</td><td>2.896026e-01</td><td>1.676743e-03</td><td>1.417736e-07</td><td>3.400842e-02</td><td>3.612272e-03</td><td>4.743024e-03</td><td>2.724614e-05</td><td>3.395150e-07</td></tr>\n",
       "\t<tr><th scope=row>⋮</th><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7430.01A</th><td>0.9774183</td><td>0.015130849</td><td>3.765206e-07</td><td>1.369697e-07</td><td>6.725784e-04</td><td>6.533762e-03</td><td>1.229668e-06</td><td>1.957884e-06</td><td>2.408299e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.D6.A74Q.01A</th><td>0.8842049</td><td>0.085482558</td><td>6.163754e-03</td><td>1.556808e-07</td><td>7.739195e-03</td><td>9.906454e-03</td><td>6.216704e-03</td><td>9.684231e-05</td><td>1.894224e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7255.01A</th><td>0.9440443</td><td>0.027434705</td><td>2.563307e-07</td><td>9.352016e-03</td><td>1.086210e-06</td><td>1.916546e-02</td><td>5.195208e-07</td><td>4.008375e-07</td><td>1.231915e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.6223.01A</th><td>0.9781348</td><td>0.006737177</td><td>3.301923e-04</td><td>1.067407e-07</td><td>1.298400e-02</td><td>2.129298e-06</td><td>1.415764e-05</td><td>5.436924e-06</td><td>1.792029e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A460.01A</th><td>0.7211691</td><td>0.150885458</td><td>2.310984e-03</td><td>1.378379e-07</td><td>3.647569e-02</td><td>3.290758e-02</td><td>7.177306e-03</td><td>4.907335e-02</td><td>4.230033e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7261.01A</th><td>0.7686271</td><td>0.199999998</td><td>1.800759e-03</td><td>1.830788e-07</td><td>1.143315e-02</td><td>1.813197e-02</td><td>8.235639e-07</td><td>3.138454e-06</td><td>2.912679e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4736.01A</th><td>0.5770123</td><td>0.202003425</td><td>3.214170e-07</td><td>1.087496e-01</td><td>8.823329e-02</td><td>1.477365e-02</td><td>1.064861e-03</td><td>1.154187e-06</td><td>8.161323e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.7404.01A</th><td>0.8335180</td><td>0.049152821</td><td>5.844858e-03</td><td>1.735372e-07</td><td>4.436907e-02</td><td>4.256713e-02</td><td>1.856149e-02</td><td>5.986233e-03</td><td>2.059526e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.UF.A719.01A</th><td>0.9767740</td><td>0.009284403</td><td>1.501744e-05</td><td>6.696999e-07</td><td>5.670974e-03</td><td>7.098415e-03</td><td>1.145896e-03</td><td>2.142360e-06</td><td>8.476798e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7236.01A</th><td>0.7583639</td><td>0.201827735</td><td>3.707119e-07</td><td>7.813978e-08</td><td>1.085050e-02</td><td>2.895305e-02</td><td>5.283327e-07</td><td>3.139558e-06</td><td>6.894808e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6951.01A</th><td>0.9146561</td><td>0.059564714</td><td>4.368603e-07</td><td>2.203449e-02</td><td>1.716345e-03</td><td>1.806717e-03</td><td>3.409096e-06</td><td>5.381342e-07</td><td>2.172331e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4728.01A</th><td>0.2860686</td><td>0.608054579</td><td>2.411349e-07</td><td>5.917761e-03</td><td>9.206015e-02</td><td>7.897528e-03</td><td>3.288993e-07</td><td>5.028132e-07</td><td>3.106541e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7090.01A</th><td>0.7096929</td><td>0.227983815</td><td>1.494937e-07</td><td>1.164804e-07</td><td>5.363601e-02</td><td>8.685670e-03</td><td>5.132976e-07</td><td>3.897865e-07</td><td>4.457247e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.5979.01A</th><td>0.9170363</td><td>0.069411556</td><td>2.913286e-07</td><td>1.650445e-03</td><td>4.982065e-03</td><td>6.916896e-03</td><td>8.838452e-07</td><td>1.062019e-06</td><td>4.597641e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.7069.01A</th><td>0.8867397</td><td>0.091163538</td><td>3.126233e-07</td><td>1.693463e-07</td><td>8.315407e-04</td><td>2.126299e-02</td><td>4.895251e-07</td><td>8.017098e-07</td><td>4.783386e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4733.01A</th><td>0.4590225</td><td>0.313208243</td><td>2.204239e-02</td><td>1.200962e-02</td><td>1.121640e-01</td><td>5.323205e-02</td><td>2.709184e-02</td><td>4.165599e-04</td><td>8.127728e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.7390.01A</th><td>0.8226924</td><td>0.170653482</td><td>1.782093e-07</td><td>1.786800e-07</td><td>3.298995e-03</td><td>3.353692e-03</td><td>3.534756e-07</td><td>3.580305e-07</td><td>3.245375e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45X.01A</th><td>0.9860628</td><td>0.005683827</td><td>8.349780e-07</td><td>3.304159e-07</td><td>7.281100e-03</td><td>9.429661e-04</td><td>2.044738e-06</td><td>7.332573e-06</td><td>1.879439e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.IQ.A6SH.01A</th><td>0.9423716</td><td>0.028385095</td><td>1.185881e-06</td><td>2.116455e-07</td><td>2.285112e-02</td><td>4.988359e-03</td><td>1.400820e-03</td><td>7.230511e-07</td><td>8.482273e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6962.11A</th><td>0.9723949</td><td>0.018871943</td><td>1.635403e-04</td><td>3.305504e-07</td><td>3.465067e-03</td><td>4.592181e-03</td><td>5.021691e-04</td><td>1.727208e-06</td><td>8.165269e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6960.11A</th><td>0.9791954</td><td>0.004831106</td><td>3.776268e-07</td><td>3.209457e-06</td><td>8.363308e-03</td><td>7.602948e-03</td><td>8.251732e-07</td><td>1.291781e-06</td><td>1.550674e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A464.01A</th><td>0.6267057</td><td>0.311161624</td><td>3.606024e-07</td><td>4.331322e-02</td><td>9.255807e-03</td><td>9.559703e-03</td><td>2.505905e-06</td><td>6.786841e-07</td><td>4.215465e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.C9.A47Z.01A</th><td>0.9654155</td><td>0.004341460</td><td>3.396085e-07</td><td>3.333502e-03</td><td>1.816612e-05</td><td>1.350464e-05</td><td>7.509604e-07</td><td>1.323662e-06</td><td>2.687544e-02</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.6010.01A</th><td>0.8331282</td><td>0.090147619</td><td>1.197741e-02</td><td>2.411752e-04</td><td>9.119946e-03</td><td>5.437399e-02</td><td>1.010305e-03</td><td>1.018232e-06</td><td>3.096677e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.WA.A7GZ.11A</th><td>0.5235703</td><td>0.003300802</td><td>1.269879e-07</td><td>4.731121e-01</td><td>3.789888e-07</td><td>1.547518e-05</td><td>2.477334e-07</td><td>2.683054e-07</td><td>3.049265e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7235.01A</th><td>0.6329990</td><td>0.323112422</td><td>1.914870e-07</td><td>9.378561e-08</td><td>2.604538e-02</td><td>1.429738e-02</td><td>3.535064e-03</td><td>1.016330e-05</td><td>2.956404e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CX.7086.01A</th><td>0.9751108</td><td>0.006095150</td><td>2.551141e-04</td><td>6.397217e-07</td><td>8.412847e-03</td><td>9.428269e-03</td><td>6.740519e-04</td><td>2.040884e-05</td><td>2.704299e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6935.11A</th><td>0.9811203</td><td>0.001239664</td><td>1.559001e-06</td><td>2.865151e-07</td><td>8.313372e-03</td><td>9.079049e-03</td><td>1.706022e-04</td><td>9.964355e-07</td><td>7.419330e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.P3.A6SW.01A</th><td>0.8650169</td><td>0.055371537</td><td>1.725337e-02</td><td>2.161523e-07</td><td>3.544294e-02</td><td>1.423648e-02</td><td>1.130333e-02</td><td>1.372259e-03</td><td>2.950967e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.HD.A6HZ.01A</th><td>0.7502374</td><td>0.116762381</td><td>8.185442e-03</td><td>3.767268e-02</td><td>5.054054e-02</td><td>2.933271e-02</td><td>4.331431e-03</td><td>2.936404e-03</td><td>1.003798e-06</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A matrix: 546 × 9 of type dbl\n",
       "\\begin{tabular}{r|lllllllll}\n",
       "  & tumor & Fibroblast & B cell & myocyte & Macrophage & Endothelial & T cell & Dendritic & Mast\\\\\n",
       "\\hline\n",
       "\tTCGA.BB.4224.01A & 0.8953963 & 3.295279e-03 & 1.535432e-07 & 2.076378e-03 & 2.663471e-06 & 1.099243e-06 & 2.711799e-07 & 4.547351e-07 & 9.922738e-02\\\\\n",
       "\tTCGA.H7.7774.01A & 0.9807876 & 9.213523e-07 & 1.956431e-06 & 1.582816e-07 & 1.186069e-02 & 7.062818e-07 & 1.267113e-04 & 1.133469e-06 & 7.220150e-03\\\\\n",
       "\tTCGA.CV.6943.01A & 0.5239461 & 3.799039e-01 & 1.548700e-03 & 2.208963e-07 & 7.545321e-02 & 8.543457e-03 & 1.060355e-02 & 3.213430e-07 & 5.962804e-07\\\\\n",
       "\tTCGA.CN.5374.01A & 0.8727039 & 2.463040e-02 & 6.619988e-03 & 6.413547e-03 & 2.021994e-02 & 2.152436e-02 & 2.999286e-02 & 1.789418e-02 & 8.044354e-07\\\\\n",
       "\tTCGA.CQ.6227.01A & 0.6538779 & 2.342006e-01 & 1.996756e-07 & 7.141557e-02 & 7.623701e-03 & 3.287952e-02 & 3.276224e-07 & 4.224889e-07 & 1.701781e-06\\\\\n",
       "\tTCGA.CV.6959.01A & 0.7848157 & 9.008879e-02 & 3.630708e-05 & 6.450137e-02 & 2.570535e-02 & 3.484607e-02 & 6.940279e-07 & 4.514340e-06 & 1.185480e-06\\\\\n",
       "\tTCGA.F7.A61V.01A & 0.9545372 & 1.147164e-02 & 1.391773e-03 & 2.241424e-02 & 4.397206e-03 & 5.219229e-03 & 5.633430e-04 & 4.516596e-06 & 8.426878e-07\\\\\n",
       "\tTCGA.CV.7413.01A & 0.7576784 & 2.165254e-01 & 1.947499e-07 & 8.478491e-08 & 2.579297e-02 & 4.341206e-07 & 1.038621e-06 & 2.309817e-07 & 1.216114e-06\\\\\n",
       "\tTCGA.CV.7247.01A & 0.7911627 & 1.108126e-01 & 1.374201e-07 & 7.858550e-02 & 6.057291e-07 & 1.943738e-02 & 1.658183e-07 & 6.054190e-07 & 2.752071e-07\\\\\n",
       "\tTCGA.CR.5249.01A & 0.8287251 & 5.001096e-02 & 7.550117e-03 & 1.137713e-07 & 2.663733e-02 & 3.129438e-02 & 3.085065e-02 & 2.493104e-02 & 3.331009e-07\\\\\n",
       "\tTCGA.CQ.5331.01A & 0.8679074 & 3.680547e-02 & 6.729025e-04 & 6.492139e-08 & 6.722354e-02 & 2.205727e-02 & 5.329257e-03 & 3.620704e-06 & 4.945356e-07\\\\\n",
       "\tTCGA.BB.8601.01A & 0.9933812 & 4.261229e-03 & 7.357805e-05 & 2.507918e-07 & 3.730104e-06 & 2.237834e-03 & 1.768300e-06 & 2.015228e-06 & 3.842106e-05\\\\\n",
       "\tTCGA.CV.A45W.01A & 0.7583385 & 9.038100e-02 & 4.573747e-02 & 2.842859e-07 & 5.930226e-02 & 3.803786e-02 & 5.694007e-03 & 2.508070e-03 & 5.767332e-07\\\\\n",
       "\tTCGA.CQ.7063.01A & 0.8932472 & 2.143019e-02 & 2.929627e-07 & 2.839658e-07 & 6.462695e-02 & 1.244862e-02 & 6.942133e-03 & 4.127833e-05 & 1.263061e-03\\\\\n",
       "\tTCGA.CN.5373.01A & 0.7648254 & 1.857341e-01 & 3.306371e-07 & 6.088100e-04 & 2.179955e-02 & 4.760714e-06 & 7.257815e-07 & 8.311730e-07 & 2.702557e-02\\\\\n",
       "\tTCGA.CV.A45T.01A & 0.8189485 & 5.773553e-02 & 5.785000e-03 & 1.473200e-02 & 6.505784e-02 & 1.423510e-02 & 1.939667e-02 & 9.113431e-05 & 4.018240e-03\\\\\n",
       "\tTCGA.HD.A4C1.01A & 0.9037093 & 8.132439e-02 & 7.313362e-07 & 1.059151e-07 & 4.587139e-03 & 1.037395e-02 & 1.168693e-06 & 1.853892e-06 & 1.389217e-06\\\\\n",
       "\tTCGA.CV.7438.11A & 0.9736846 & 2.405088e-03 & 6.825740e-04 & 2.766721e-03 & 1.248155e-02 & 1.094154e-03 & 6.450133e-03 & 1.981943e-04 & 2.369504e-04\\\\\n",
       "\tTCGA.CV.5444.01A & 0.4018990 & 5.008603e-01 & 1.421520e-07 & 3.634083e-02 & 5.472763e-02 & 6.170893e-03 & 4.490983e-07 & 4.175766e-07 & 2.911519e-07\\\\\n",
       "\tTCGA.BA.5556.01A & 0.8490606 & 4.796692e-02 & 2.149780e-05 & 9.793571e-08 & 5.747951e-02 & 2.534477e-02 & 1.919881e-02 & 9.241382e-04 & 3.625550e-06\\\\\n",
       "\tTCGA.P3.A6SX.01A & 0.8960362 & 9.110862e-02 & 1.878011e-07 & 1.098512e-02 & 6.988049e-07 & 1.867874e-03 & 4.670143e-07 & 3.429470e-07 & 5.174869e-07\\\\\n",
       "\tTCGA.CV.7242.11A & 0.9755767 & 5.311162e-03 & 3.153993e-05 & 3.141680e-07 & 1.229840e-02 & 4.594129e-03 & 2.158675e-03 & 2.730977e-05 & 1.801851e-06\\\\\n",
       "\tTCGA.DQ.7592.01A & 0.8323528 & 1.342008e-01 & 1.722611e-07 & 1.280968e-02 & 1.281682e-02 & 5.765994e-03 & 9.210478e-04 & 8.855847e-07 & 1.131870e-03\\\\\n",
       "\tTCGA.CV.6937.01A & 0.8360634 & 1.441721e-01 & 3.585737e-07 & 4.275409e-07 & 1.778293e-02 & 1.976317e-03 & 7.544563e-07 & 3.166395e-06 & 5.797741e-07\\\\\n",
       "\tTCGA.QK.A8ZB.01A & 0.8499897 & 1.257516e-01 & 6.130647e-03 & 1.031490e-07 & 6.951394e-03 & 7.469520e-03 & 5.701797e-07 & 1.859023e-06 & 3.704592e-03\\\\\n",
       "\tTCGA.CV.7432.01A & 0.9688731 & 2.165490e-02 & 1.442955e-07 & 1.739435e-07 & 4.331192e-03 & 5.137664e-03 & 3.056553e-07 & 1.084470e-06 & 1.401741e-06\\\\\n",
       "\tTCGA.CV.7089.01A & 0.9668070 & 8.355609e-03 & 2.990496e-07 & 1.403883e-07 & 8.618054e-03 & 1.516107e-02 & 1.011682e-03 & 6.487607e-06 & 3.969543e-05\\\\\n",
       "\tTCGA.CV.6939.11A & 0.3108183 & 2.925750e-02 & 1.597606e-03 & 6.230553e-01 & 1.509185e-03 & 3.375961e-02 & 2.043617e-06 & 2.373454e-07 & 1.717001e-07\\\\\n",
       "\tTCGA.BA.4075.01A & 0.9198085 & 4.745561e-02 & 3.472322e-07 & 2.176400e-03 & 2.556290e-02 & 4.994196e-03 & 7.253185e-07 & 9.011630e-07 & 4.677923e-07\\\\\n",
       "\tTCGA.T3.A92M.01A & 0.6663292 & 2.896026e-01 & 1.676743e-03 & 1.417736e-07 & 3.400842e-02 & 3.612272e-03 & 4.743024e-03 & 2.724614e-05 & 3.395150e-07\\\\\n",
       "\t⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n",
       "\tTCGA.CV.7430.01A & 0.9774183 & 0.015130849 & 3.765206e-07 & 1.369697e-07 & 6.725784e-04 & 6.533762e-03 & 1.229668e-06 & 1.957884e-06 & 2.408299e-04\\\\\n",
       "\tTCGA.D6.A74Q.01A & 0.8842049 & 0.085482558 & 6.163754e-03 & 1.556808e-07 & 7.739195e-03 & 9.906454e-03 & 6.216704e-03 & 9.684231e-05 & 1.894224e-04\\\\\n",
       "\tTCGA.CV.7255.01A & 0.9440443 & 0.027434705 & 2.563307e-07 & 9.352016e-03 & 1.086210e-06 & 1.916546e-02 & 5.195208e-07 & 4.008375e-07 & 1.231915e-06\\\\\n",
       "\tTCGA.CQ.6223.01A & 0.9781348 & 0.006737177 & 3.301923e-04 & 1.067407e-07 & 1.298400e-02 & 2.129298e-06 & 1.415764e-05 & 5.436924e-06 & 1.792029e-03\\\\\n",
       "\tTCGA.CV.A460.01A & 0.7211691 & 0.150885458 & 2.310984e-03 & 1.378379e-07 & 3.647569e-02 & 3.290758e-02 & 7.177306e-03 & 4.907335e-02 & 4.230033e-07\\\\\n",
       "\tTCGA.CV.7261.01A & 0.7686271 & 0.199999998 & 1.800759e-03 & 1.830788e-07 & 1.143315e-02 & 1.813197e-02 & 8.235639e-07 & 3.138454e-06 & 2.912679e-06\\\\\n",
       "\tTCGA.CN.4736.01A & 0.5770123 & 0.202003425 & 3.214170e-07 & 1.087496e-01 & 8.823329e-02 & 1.477365e-02 & 1.064861e-03 & 1.154187e-06 & 8.161323e-03\\\\\n",
       "\tTCGA.CR.7404.01A & 0.8335180 & 0.049152821 & 5.844858e-03 & 1.735372e-07 & 4.436907e-02 & 4.256713e-02 & 1.856149e-02 & 5.986233e-03 & 2.059526e-07\\\\\n",
       "\tTCGA.UF.A719.01A & 0.9767740 & 0.009284403 & 1.501744e-05 & 6.696999e-07 & 5.670974e-03 & 7.098415e-03 & 1.145896e-03 & 2.142360e-06 & 8.476798e-06\\\\\n",
       "\tTCGA.CV.7236.01A & 0.7583639 & 0.201827735 & 3.707119e-07 & 7.813978e-08 & 1.085050e-02 & 2.895305e-02 & 5.283327e-07 & 3.139558e-06 & 6.894808e-07\\\\\n",
       "\tTCGA.CV.6951.01A & 0.9146561 & 0.059564714 & 4.368603e-07 & 2.203449e-02 & 1.716345e-03 & 1.806717e-03 & 3.409096e-06 & 5.381342e-07 & 2.172331e-04\\\\\n",
       "\tTCGA.CN.4728.01A & 0.2860686 & 0.608054579 & 2.411349e-07 & 5.917761e-03 & 9.206015e-02 & 7.897528e-03 & 3.288993e-07 & 5.028132e-07 & 3.106541e-07\\\\\n",
       "\tTCGA.CV.7090.01A & 0.7096929 & 0.227983815 & 1.494937e-07 & 1.164804e-07 & 5.363601e-02 & 8.685670e-03 & 5.132976e-07 & 3.897865e-07 & 4.457247e-07\\\\\n",
       "\tTCGA.CV.5979.01A & 0.9170363 & 0.069411556 & 2.913286e-07 & 1.650445e-03 & 4.982065e-03 & 6.916896e-03 & 8.838452e-07 & 1.062019e-06 & 4.597641e-07\\\\\n",
       "\tTCGA.CQ.7069.01A & 0.8867397 & 0.091163538 & 3.126233e-07 & 1.693463e-07 & 8.315407e-04 & 2.126299e-02 & 4.895251e-07 & 8.017098e-07 & 4.783386e-07\\\\\n",
       "\tTCGA.CN.4733.01A & 0.4590225 & 0.313208243 & 2.204239e-02 & 1.200962e-02 & 1.121640e-01 & 5.323205e-02 & 2.709184e-02 & 4.165599e-04 & 8.127728e-04\\\\\n",
       "\tTCGA.CR.7390.01A & 0.8226924 & 0.170653482 & 1.782093e-07 & 1.786800e-07 & 3.298995e-03 & 3.353692e-03 & 3.534756e-07 & 3.580305e-07 & 3.245375e-07\\\\\n",
       "\tTCGA.CV.A45X.01A & 0.9860628 & 0.005683827 & 8.349780e-07 & 3.304159e-07 & 7.281100e-03 & 9.429661e-04 & 2.044738e-06 & 7.332573e-06 & 1.879439e-05\\\\\n",
       "\tTCGA.IQ.A6SH.01A & 0.9423716 & 0.028385095 & 1.185881e-06 & 2.116455e-07 & 2.285112e-02 & 4.988359e-03 & 1.400820e-03 & 7.230511e-07 & 8.482273e-07\\\\\n",
       "\tTCGA.CV.6962.11A & 0.9723949 & 0.018871943 & 1.635403e-04 & 3.305504e-07 & 3.465067e-03 & 4.592181e-03 & 5.021691e-04 & 1.727208e-06 & 8.165269e-06\\\\\n",
       "\tTCGA.CV.6960.11A & 0.9791954 & 0.004831106 & 3.776268e-07 & 3.209457e-06 & 8.363308e-03 & 7.602948e-03 & 8.251732e-07 & 1.291781e-06 & 1.550674e-06\\\\\n",
       "\tTCGA.CV.A464.01A & 0.6267057 & 0.311161624 & 3.606024e-07 & 4.331322e-02 & 9.255807e-03 & 9.559703e-03 & 2.505905e-06 & 6.786841e-07 & 4.215465e-07\\\\\n",
       "\tTCGA.C9.A47Z.01A & 0.9654155 & 0.004341460 & 3.396085e-07 & 3.333502e-03 & 1.816612e-05 & 1.350464e-05 & 7.509604e-07 & 1.323662e-06 & 2.687544e-02\\\\\n",
       "\tTCGA.CN.6010.01A & 0.8331282 & 0.090147619 & 1.197741e-02 & 2.411752e-04 & 9.119946e-03 & 5.437399e-02 & 1.010305e-03 & 1.018232e-06 & 3.096677e-07\\\\\n",
       "\tTCGA.WA.A7GZ.11A & 0.5235703 & 0.003300802 & 1.269879e-07 & 4.731121e-01 & 3.789888e-07 & 1.547518e-05 & 2.477334e-07 & 2.683054e-07 & 3.049265e-07\\\\\n",
       "\tTCGA.CV.7235.01A & 0.6329990 & 0.323112422 & 1.914870e-07 & 9.378561e-08 & 2.604538e-02 & 1.429738e-02 & 3.535064e-03 & 1.016330e-05 & 2.956404e-07\\\\\n",
       "\tTCGA.CX.7086.01A & 0.9751108 & 0.006095150 & 2.551141e-04 & 6.397217e-07 & 8.412847e-03 & 9.428269e-03 & 6.740519e-04 & 2.040884e-05 & 2.704299e-06\\\\\n",
       "\tTCGA.CV.6935.11A & 0.9811203 & 0.001239664 & 1.559001e-06 & 2.865151e-07 & 8.313372e-03 & 9.079049e-03 & 1.706022e-04 & 9.964355e-07 & 7.419330e-05\\\\\n",
       "\tTCGA.P3.A6SW.01A & 0.8650169 & 0.055371537 & 1.725337e-02 & 2.161523e-07 & 3.544294e-02 & 1.423648e-02 & 1.130333e-02 & 1.372259e-03 & 2.950967e-06\\\\\n",
       "\tTCGA.HD.A6HZ.01A & 0.7502374 & 0.116762381 & 8.185442e-03 & 3.767268e-02 & 5.054054e-02 & 2.933271e-02 & 4.331431e-03 & 2.936404e-03 & 1.003798e-06\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A matrix: 546 × 9 of type dbl\n",
       "\n",
       "| <!--/--> | tumor | Fibroblast | B cell | myocyte | Macrophage | Endothelial | T cell | Dendritic | Mast |\n",
       "|---|---|---|---|---|---|---|---|---|---|\n",
       "| TCGA.BB.4224.01A | 0.8953963 | 3.295279e-03 | 1.535432e-07 | 2.076378e-03 | 2.663471e-06 | 1.099243e-06 | 2.711799e-07 | 4.547351e-07 | 9.922738e-02 |\n",
       "| TCGA.H7.7774.01A | 0.9807876 | 9.213523e-07 | 1.956431e-06 | 1.582816e-07 | 1.186069e-02 | 7.062818e-07 | 1.267113e-04 | 1.133469e-06 | 7.220150e-03 |\n",
       "| TCGA.CV.6943.01A | 0.5239461 | 3.799039e-01 | 1.548700e-03 | 2.208963e-07 | 7.545321e-02 | 8.543457e-03 | 1.060355e-02 | 3.213430e-07 | 5.962804e-07 |\n",
       "| TCGA.CN.5374.01A | 0.8727039 | 2.463040e-02 | 6.619988e-03 | 6.413547e-03 | 2.021994e-02 | 2.152436e-02 | 2.999286e-02 | 1.789418e-02 | 8.044354e-07 |\n",
       "| TCGA.CQ.6227.01A | 0.6538779 | 2.342006e-01 | 1.996756e-07 | 7.141557e-02 | 7.623701e-03 | 3.287952e-02 | 3.276224e-07 | 4.224889e-07 | 1.701781e-06 |\n",
       "| TCGA.CV.6959.01A | 0.7848157 | 9.008879e-02 | 3.630708e-05 | 6.450137e-02 | 2.570535e-02 | 3.484607e-02 | 6.940279e-07 | 4.514340e-06 | 1.185480e-06 |\n",
       "| TCGA.F7.A61V.01A | 0.9545372 | 1.147164e-02 | 1.391773e-03 | 2.241424e-02 | 4.397206e-03 | 5.219229e-03 | 5.633430e-04 | 4.516596e-06 | 8.426878e-07 |\n",
       "| TCGA.CV.7413.01A | 0.7576784 | 2.165254e-01 | 1.947499e-07 | 8.478491e-08 | 2.579297e-02 | 4.341206e-07 | 1.038621e-06 | 2.309817e-07 | 1.216114e-06 |\n",
       "| TCGA.CV.7247.01A | 0.7911627 | 1.108126e-01 | 1.374201e-07 | 7.858550e-02 | 6.057291e-07 | 1.943738e-02 | 1.658183e-07 | 6.054190e-07 | 2.752071e-07 |\n",
       "| TCGA.CR.5249.01A | 0.8287251 | 5.001096e-02 | 7.550117e-03 | 1.137713e-07 | 2.663733e-02 | 3.129438e-02 | 3.085065e-02 | 2.493104e-02 | 3.331009e-07 |\n",
       "| TCGA.CQ.5331.01A | 0.8679074 | 3.680547e-02 | 6.729025e-04 | 6.492139e-08 | 6.722354e-02 | 2.205727e-02 | 5.329257e-03 | 3.620704e-06 | 4.945356e-07 |\n",
       "| TCGA.BB.8601.01A | 0.9933812 | 4.261229e-03 | 7.357805e-05 | 2.507918e-07 | 3.730104e-06 | 2.237834e-03 | 1.768300e-06 | 2.015228e-06 | 3.842106e-05 |\n",
       "| TCGA.CV.A45W.01A | 0.7583385 | 9.038100e-02 | 4.573747e-02 | 2.842859e-07 | 5.930226e-02 | 3.803786e-02 | 5.694007e-03 | 2.508070e-03 | 5.767332e-07 |\n",
       "| TCGA.CQ.7063.01A | 0.8932472 | 2.143019e-02 | 2.929627e-07 | 2.839658e-07 | 6.462695e-02 | 1.244862e-02 | 6.942133e-03 | 4.127833e-05 | 1.263061e-03 |\n",
       "| TCGA.CN.5373.01A | 0.7648254 | 1.857341e-01 | 3.306371e-07 | 6.088100e-04 | 2.179955e-02 | 4.760714e-06 | 7.257815e-07 | 8.311730e-07 | 2.702557e-02 |\n",
       "| TCGA.CV.A45T.01A | 0.8189485 | 5.773553e-02 | 5.785000e-03 | 1.473200e-02 | 6.505784e-02 | 1.423510e-02 | 1.939667e-02 | 9.113431e-05 | 4.018240e-03 |\n",
       "| TCGA.HD.A4C1.01A | 0.9037093 | 8.132439e-02 | 7.313362e-07 | 1.059151e-07 | 4.587139e-03 | 1.037395e-02 | 1.168693e-06 | 1.853892e-06 | 1.389217e-06 |\n",
       "| TCGA.CV.7438.11A | 0.9736846 | 2.405088e-03 | 6.825740e-04 | 2.766721e-03 | 1.248155e-02 | 1.094154e-03 | 6.450133e-03 | 1.981943e-04 | 2.369504e-04 |\n",
       "| TCGA.CV.5444.01A | 0.4018990 | 5.008603e-01 | 1.421520e-07 | 3.634083e-02 | 5.472763e-02 | 6.170893e-03 | 4.490983e-07 | 4.175766e-07 | 2.911519e-07 |\n",
       "| TCGA.BA.5556.01A | 0.8490606 | 4.796692e-02 | 2.149780e-05 | 9.793571e-08 | 5.747951e-02 | 2.534477e-02 | 1.919881e-02 | 9.241382e-04 | 3.625550e-06 |\n",
       "| TCGA.P3.A6SX.01A | 0.8960362 | 9.110862e-02 | 1.878011e-07 | 1.098512e-02 | 6.988049e-07 | 1.867874e-03 | 4.670143e-07 | 3.429470e-07 | 5.174869e-07 |\n",
       "| TCGA.CV.7242.11A | 0.9755767 | 5.311162e-03 | 3.153993e-05 | 3.141680e-07 | 1.229840e-02 | 4.594129e-03 | 2.158675e-03 | 2.730977e-05 | 1.801851e-06 |\n",
       "| TCGA.DQ.7592.01A | 0.8323528 | 1.342008e-01 | 1.722611e-07 | 1.280968e-02 | 1.281682e-02 | 5.765994e-03 | 9.210478e-04 | 8.855847e-07 | 1.131870e-03 |\n",
       "| TCGA.CV.6937.01A | 0.8360634 | 1.441721e-01 | 3.585737e-07 | 4.275409e-07 | 1.778293e-02 | 1.976317e-03 | 7.544563e-07 | 3.166395e-06 | 5.797741e-07 |\n",
       "| TCGA.QK.A8ZB.01A | 0.8499897 | 1.257516e-01 | 6.130647e-03 | 1.031490e-07 | 6.951394e-03 | 7.469520e-03 | 5.701797e-07 | 1.859023e-06 | 3.704592e-03 |\n",
       "| TCGA.CV.7432.01A | 0.9688731 | 2.165490e-02 | 1.442955e-07 | 1.739435e-07 | 4.331192e-03 | 5.137664e-03 | 3.056553e-07 | 1.084470e-06 | 1.401741e-06 |\n",
       "| TCGA.CV.7089.01A | 0.9668070 | 8.355609e-03 | 2.990496e-07 | 1.403883e-07 | 8.618054e-03 | 1.516107e-02 | 1.011682e-03 | 6.487607e-06 | 3.969543e-05 |\n",
       "| TCGA.CV.6939.11A | 0.3108183 | 2.925750e-02 | 1.597606e-03 | 6.230553e-01 | 1.509185e-03 | 3.375961e-02 | 2.043617e-06 | 2.373454e-07 | 1.717001e-07 |\n",
       "| TCGA.BA.4075.01A | 0.9198085 | 4.745561e-02 | 3.472322e-07 | 2.176400e-03 | 2.556290e-02 | 4.994196e-03 | 7.253185e-07 | 9.011630e-07 | 4.677923e-07 |\n",
       "| TCGA.T3.A92M.01A | 0.6663292 | 2.896026e-01 | 1.676743e-03 | 1.417736e-07 | 3.400842e-02 | 3.612272e-03 | 4.743024e-03 | 2.724614e-05 | 3.395150e-07 |\n",
       "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ |\n",
       "| TCGA.CV.7430.01A | 0.9774183 | 0.015130849 | 3.765206e-07 | 1.369697e-07 | 6.725784e-04 | 6.533762e-03 | 1.229668e-06 | 1.957884e-06 | 2.408299e-04 |\n",
       "| TCGA.D6.A74Q.01A | 0.8842049 | 0.085482558 | 6.163754e-03 | 1.556808e-07 | 7.739195e-03 | 9.906454e-03 | 6.216704e-03 | 9.684231e-05 | 1.894224e-04 |\n",
       "| TCGA.CV.7255.01A | 0.9440443 | 0.027434705 | 2.563307e-07 | 9.352016e-03 | 1.086210e-06 | 1.916546e-02 | 5.195208e-07 | 4.008375e-07 | 1.231915e-06 |\n",
       "| TCGA.CQ.6223.01A | 0.9781348 | 0.006737177 | 3.301923e-04 | 1.067407e-07 | 1.298400e-02 | 2.129298e-06 | 1.415764e-05 | 5.436924e-06 | 1.792029e-03 |\n",
       "| TCGA.CV.A460.01A | 0.7211691 | 0.150885458 | 2.310984e-03 | 1.378379e-07 | 3.647569e-02 | 3.290758e-02 | 7.177306e-03 | 4.907335e-02 | 4.230033e-07 |\n",
       "| TCGA.CV.7261.01A | 0.7686271 | 0.199999998 | 1.800759e-03 | 1.830788e-07 | 1.143315e-02 | 1.813197e-02 | 8.235639e-07 | 3.138454e-06 | 2.912679e-06 |\n",
       "| TCGA.CN.4736.01A | 0.5770123 | 0.202003425 | 3.214170e-07 | 1.087496e-01 | 8.823329e-02 | 1.477365e-02 | 1.064861e-03 | 1.154187e-06 | 8.161323e-03 |\n",
       "| TCGA.CR.7404.01A | 0.8335180 | 0.049152821 | 5.844858e-03 | 1.735372e-07 | 4.436907e-02 | 4.256713e-02 | 1.856149e-02 | 5.986233e-03 | 2.059526e-07 |\n",
       "| TCGA.UF.A719.01A | 0.9767740 | 0.009284403 | 1.501744e-05 | 6.696999e-07 | 5.670974e-03 | 7.098415e-03 | 1.145896e-03 | 2.142360e-06 | 8.476798e-06 |\n",
       "| TCGA.CV.7236.01A | 0.7583639 | 0.201827735 | 3.707119e-07 | 7.813978e-08 | 1.085050e-02 | 2.895305e-02 | 5.283327e-07 | 3.139558e-06 | 6.894808e-07 |\n",
       "| TCGA.CV.6951.01A | 0.9146561 | 0.059564714 | 4.368603e-07 | 2.203449e-02 | 1.716345e-03 | 1.806717e-03 | 3.409096e-06 | 5.381342e-07 | 2.172331e-04 |\n",
       "| TCGA.CN.4728.01A | 0.2860686 | 0.608054579 | 2.411349e-07 | 5.917761e-03 | 9.206015e-02 | 7.897528e-03 | 3.288993e-07 | 5.028132e-07 | 3.106541e-07 |\n",
       "| TCGA.CV.7090.01A | 0.7096929 | 0.227983815 | 1.494937e-07 | 1.164804e-07 | 5.363601e-02 | 8.685670e-03 | 5.132976e-07 | 3.897865e-07 | 4.457247e-07 |\n",
       "| TCGA.CV.5979.01A | 0.9170363 | 0.069411556 | 2.913286e-07 | 1.650445e-03 | 4.982065e-03 | 6.916896e-03 | 8.838452e-07 | 1.062019e-06 | 4.597641e-07 |\n",
       "| TCGA.CQ.7069.01A | 0.8867397 | 0.091163538 | 3.126233e-07 | 1.693463e-07 | 8.315407e-04 | 2.126299e-02 | 4.895251e-07 | 8.017098e-07 | 4.783386e-07 |\n",
       "| TCGA.CN.4733.01A | 0.4590225 | 0.313208243 | 2.204239e-02 | 1.200962e-02 | 1.121640e-01 | 5.323205e-02 | 2.709184e-02 | 4.165599e-04 | 8.127728e-04 |\n",
       "| TCGA.CR.7390.01A | 0.8226924 | 0.170653482 | 1.782093e-07 | 1.786800e-07 | 3.298995e-03 | 3.353692e-03 | 3.534756e-07 | 3.580305e-07 | 3.245375e-07 |\n",
       "| TCGA.CV.A45X.01A | 0.9860628 | 0.005683827 | 8.349780e-07 | 3.304159e-07 | 7.281100e-03 | 9.429661e-04 | 2.044738e-06 | 7.332573e-06 | 1.879439e-05 |\n",
       "| TCGA.IQ.A6SH.01A | 0.9423716 | 0.028385095 | 1.185881e-06 | 2.116455e-07 | 2.285112e-02 | 4.988359e-03 | 1.400820e-03 | 7.230511e-07 | 8.482273e-07 |\n",
       "| TCGA.CV.6962.11A | 0.9723949 | 0.018871943 | 1.635403e-04 | 3.305504e-07 | 3.465067e-03 | 4.592181e-03 | 5.021691e-04 | 1.727208e-06 | 8.165269e-06 |\n",
       "| TCGA.CV.6960.11A | 0.9791954 | 0.004831106 | 3.776268e-07 | 3.209457e-06 | 8.363308e-03 | 7.602948e-03 | 8.251732e-07 | 1.291781e-06 | 1.550674e-06 |\n",
       "| TCGA.CV.A464.01A | 0.6267057 | 0.311161624 | 3.606024e-07 | 4.331322e-02 | 9.255807e-03 | 9.559703e-03 | 2.505905e-06 | 6.786841e-07 | 4.215465e-07 |\n",
       "| TCGA.C9.A47Z.01A | 0.9654155 | 0.004341460 | 3.396085e-07 | 3.333502e-03 | 1.816612e-05 | 1.350464e-05 | 7.509604e-07 | 1.323662e-06 | 2.687544e-02 |\n",
       "| TCGA.CN.6010.01A | 0.8331282 | 0.090147619 | 1.197741e-02 | 2.411752e-04 | 9.119946e-03 | 5.437399e-02 | 1.010305e-03 | 1.018232e-06 | 3.096677e-07 |\n",
       "| TCGA.WA.A7GZ.11A | 0.5235703 | 0.003300802 | 1.269879e-07 | 4.731121e-01 | 3.789888e-07 | 1.547518e-05 | 2.477334e-07 | 2.683054e-07 | 3.049265e-07 |\n",
       "| TCGA.CV.7235.01A | 0.6329990 | 0.323112422 | 1.914870e-07 | 9.378561e-08 | 2.604538e-02 | 1.429738e-02 | 3.535064e-03 | 1.016330e-05 | 2.956404e-07 |\n",
       "| TCGA.CX.7086.01A | 0.9751108 | 0.006095150 | 2.551141e-04 | 6.397217e-07 | 8.412847e-03 | 9.428269e-03 | 6.740519e-04 | 2.040884e-05 | 2.704299e-06 |\n",
       "| TCGA.CV.6935.11A | 0.9811203 | 0.001239664 | 1.559001e-06 | 2.865151e-07 | 8.313372e-03 | 9.079049e-03 | 1.706022e-04 | 9.964355e-07 | 7.419330e-05 |\n",
       "| TCGA.P3.A6SW.01A | 0.8650169 | 0.055371537 | 1.725337e-02 | 2.161523e-07 | 3.544294e-02 | 1.423648e-02 | 1.130333e-02 | 1.372259e-03 | 2.950967e-06 |\n",
       "| TCGA.HD.A6HZ.01A | 0.7502374 | 0.116762381 | 8.185442e-03 | 3.767268e-02 | 5.054054e-02 | 2.933271e-02 | 4.331431e-03 | 2.936404e-03 | 1.003798e-06 |\n",
       "\n"
      ],
      "text/plain": [
       "                 tumor     Fibroblast   B cell       myocyte      Macrophage  \n",
       "TCGA.BB.4224.01A 0.8953963 3.295279e-03 1.535432e-07 2.076378e-03 2.663471e-06\n",
       "TCGA.H7.7774.01A 0.9807876 9.213523e-07 1.956431e-06 1.582816e-07 1.186069e-02\n",
       "TCGA.CV.6943.01A 0.5239461 3.799039e-01 1.548700e-03 2.208963e-07 7.545321e-02\n",
       "TCGA.CN.5374.01A 0.8727039 2.463040e-02 6.619988e-03 6.413547e-03 2.021994e-02\n",
       "TCGA.CQ.6227.01A 0.6538779 2.342006e-01 1.996756e-07 7.141557e-02 7.623701e-03\n",
       "TCGA.CV.6959.01A 0.7848157 9.008879e-02 3.630708e-05 6.450137e-02 2.570535e-02\n",
       "TCGA.F7.A61V.01A 0.9545372 1.147164e-02 1.391773e-03 2.241424e-02 4.397206e-03\n",
       "TCGA.CV.7413.01A 0.7576784 2.165254e-01 1.947499e-07 8.478491e-08 2.579297e-02\n",
       "TCGA.CV.7247.01A 0.7911627 1.108126e-01 1.374201e-07 7.858550e-02 6.057291e-07\n",
       "TCGA.CR.5249.01A 0.8287251 5.001096e-02 7.550117e-03 1.137713e-07 2.663733e-02\n",
       "TCGA.CQ.5331.01A 0.8679074 3.680547e-02 6.729025e-04 6.492139e-08 6.722354e-02\n",
       "TCGA.BB.8601.01A 0.9933812 4.261229e-03 7.357805e-05 2.507918e-07 3.730104e-06\n",
       "TCGA.CV.A45W.01A 0.7583385 9.038100e-02 4.573747e-02 2.842859e-07 5.930226e-02\n",
       "TCGA.CQ.7063.01A 0.8932472 2.143019e-02 2.929627e-07 2.839658e-07 6.462695e-02\n",
       "TCGA.CN.5373.01A 0.7648254 1.857341e-01 3.306371e-07 6.088100e-04 2.179955e-02\n",
       "TCGA.CV.A45T.01A 0.8189485 5.773553e-02 5.785000e-03 1.473200e-02 6.505784e-02\n",
       "TCGA.HD.A4C1.01A 0.9037093 8.132439e-02 7.313362e-07 1.059151e-07 4.587139e-03\n",
       "TCGA.CV.7438.11A 0.9736846 2.405088e-03 6.825740e-04 2.766721e-03 1.248155e-02\n",
       "TCGA.CV.5444.01A 0.4018990 5.008603e-01 1.421520e-07 3.634083e-02 5.472763e-02\n",
       "TCGA.BA.5556.01A 0.8490606 4.796692e-02 2.149780e-05 9.793571e-08 5.747951e-02\n",
       "TCGA.P3.A6SX.01A 0.8960362 9.110862e-02 1.878011e-07 1.098512e-02 6.988049e-07\n",
       "TCGA.CV.7242.11A 0.9755767 5.311162e-03 3.153993e-05 3.141680e-07 1.229840e-02\n",
       "TCGA.DQ.7592.01A 0.8323528 1.342008e-01 1.722611e-07 1.280968e-02 1.281682e-02\n",
       "TCGA.CV.6937.01A 0.8360634 1.441721e-01 3.585737e-07 4.275409e-07 1.778293e-02\n",
       "TCGA.QK.A8ZB.01A 0.8499897 1.257516e-01 6.130647e-03 1.031490e-07 6.951394e-03\n",
       "TCGA.CV.7432.01A 0.9688731 2.165490e-02 1.442955e-07 1.739435e-07 4.331192e-03\n",
       "TCGA.CV.7089.01A 0.9668070 8.355609e-03 2.990496e-07 1.403883e-07 8.618054e-03\n",
       "TCGA.CV.6939.11A 0.3108183 2.925750e-02 1.597606e-03 6.230553e-01 1.509185e-03\n",
       "TCGA.BA.4075.01A 0.9198085 4.745561e-02 3.472322e-07 2.176400e-03 2.556290e-02\n",
       "TCGA.T3.A92M.01A 0.6663292 2.896026e-01 1.676743e-03 1.417736e-07 3.400842e-02\n",
       "⋮                ⋮         ⋮            ⋮            ⋮            ⋮           \n",
       "TCGA.CV.7430.01A 0.9774183 0.015130849  3.765206e-07 1.369697e-07 6.725784e-04\n",
       "TCGA.D6.A74Q.01A 0.8842049 0.085482558  6.163754e-03 1.556808e-07 7.739195e-03\n",
       "TCGA.CV.7255.01A 0.9440443 0.027434705  2.563307e-07 9.352016e-03 1.086210e-06\n",
       "TCGA.CQ.6223.01A 0.9781348 0.006737177  3.301923e-04 1.067407e-07 1.298400e-02\n",
       "TCGA.CV.A460.01A 0.7211691 0.150885458  2.310984e-03 1.378379e-07 3.647569e-02\n",
       "TCGA.CV.7261.01A 0.7686271 0.199999998  1.800759e-03 1.830788e-07 1.143315e-02\n",
       "TCGA.CN.4736.01A 0.5770123 0.202003425  3.214170e-07 1.087496e-01 8.823329e-02\n",
       "TCGA.CR.7404.01A 0.8335180 0.049152821  5.844858e-03 1.735372e-07 4.436907e-02\n",
       "TCGA.UF.A719.01A 0.9767740 0.009284403  1.501744e-05 6.696999e-07 5.670974e-03\n",
       "TCGA.CV.7236.01A 0.7583639 0.201827735  3.707119e-07 7.813978e-08 1.085050e-02\n",
       "TCGA.CV.6951.01A 0.9146561 0.059564714  4.368603e-07 2.203449e-02 1.716345e-03\n",
       "TCGA.CN.4728.01A 0.2860686 0.608054579  2.411349e-07 5.917761e-03 9.206015e-02\n",
       "TCGA.CV.7090.01A 0.7096929 0.227983815  1.494937e-07 1.164804e-07 5.363601e-02\n",
       "TCGA.CV.5979.01A 0.9170363 0.069411556  2.913286e-07 1.650445e-03 4.982065e-03\n",
       "TCGA.CQ.7069.01A 0.8867397 0.091163538  3.126233e-07 1.693463e-07 8.315407e-04\n",
       "TCGA.CN.4733.01A 0.4590225 0.313208243  2.204239e-02 1.200962e-02 1.121640e-01\n",
       "TCGA.CR.7390.01A 0.8226924 0.170653482  1.782093e-07 1.786800e-07 3.298995e-03\n",
       "TCGA.CV.A45X.01A 0.9860628 0.005683827  8.349780e-07 3.304159e-07 7.281100e-03\n",
       "TCGA.IQ.A6SH.01A 0.9423716 0.028385095  1.185881e-06 2.116455e-07 2.285112e-02\n",
       "TCGA.CV.6962.11A 0.9723949 0.018871943  1.635403e-04 3.305504e-07 3.465067e-03\n",
       "TCGA.CV.6960.11A 0.9791954 0.004831106  3.776268e-07 3.209457e-06 8.363308e-03\n",
       "TCGA.CV.A464.01A 0.6267057 0.311161624  3.606024e-07 4.331322e-02 9.255807e-03\n",
       "TCGA.C9.A47Z.01A 0.9654155 0.004341460  3.396085e-07 3.333502e-03 1.816612e-05\n",
       "TCGA.CN.6010.01A 0.8331282 0.090147619  1.197741e-02 2.411752e-04 9.119946e-03\n",
       "TCGA.WA.A7GZ.11A 0.5235703 0.003300802  1.269879e-07 4.731121e-01 3.789888e-07\n",
       "TCGA.CV.7235.01A 0.6329990 0.323112422  1.914870e-07 9.378561e-08 2.604538e-02\n",
       "TCGA.CX.7086.01A 0.9751108 0.006095150  2.551141e-04 6.397217e-07 8.412847e-03\n",
       "TCGA.CV.6935.11A 0.9811203 0.001239664  1.559001e-06 2.865151e-07 8.313372e-03\n",
       "TCGA.P3.A6SW.01A 0.8650169 0.055371537  1.725337e-02 2.161523e-07 3.544294e-02\n",
       "TCGA.HD.A6HZ.01A 0.7502374 0.116762381  8.185442e-03 3.767268e-02 5.054054e-02\n",
       "                 Endothelial  T cell       Dendritic    Mast        \n",
       "TCGA.BB.4224.01A 1.099243e-06 2.711799e-07 4.547351e-07 9.922738e-02\n",
       "TCGA.H7.7774.01A 7.062818e-07 1.267113e-04 1.133469e-06 7.220150e-03\n",
       "TCGA.CV.6943.01A 8.543457e-03 1.060355e-02 3.213430e-07 5.962804e-07\n",
       "TCGA.CN.5374.01A 2.152436e-02 2.999286e-02 1.789418e-02 8.044354e-07\n",
       "TCGA.CQ.6227.01A 3.287952e-02 3.276224e-07 4.224889e-07 1.701781e-06\n",
       "TCGA.CV.6959.01A 3.484607e-02 6.940279e-07 4.514340e-06 1.185480e-06\n",
       "TCGA.F7.A61V.01A 5.219229e-03 5.633430e-04 4.516596e-06 8.426878e-07\n",
       "TCGA.CV.7413.01A 4.341206e-07 1.038621e-06 2.309817e-07 1.216114e-06\n",
       "TCGA.CV.7247.01A 1.943738e-02 1.658183e-07 6.054190e-07 2.752071e-07\n",
       "TCGA.CR.5249.01A 3.129438e-02 3.085065e-02 2.493104e-02 3.331009e-07\n",
       "TCGA.CQ.5331.01A 2.205727e-02 5.329257e-03 3.620704e-06 4.945356e-07\n",
       "TCGA.BB.8601.01A 2.237834e-03 1.768300e-06 2.015228e-06 3.842106e-05\n",
       "TCGA.CV.A45W.01A 3.803786e-02 5.694007e-03 2.508070e-03 5.767332e-07\n",
       "TCGA.CQ.7063.01A 1.244862e-02 6.942133e-03 4.127833e-05 1.263061e-03\n",
       "TCGA.CN.5373.01A 4.760714e-06 7.257815e-07 8.311730e-07 2.702557e-02\n",
       "TCGA.CV.A45T.01A 1.423510e-02 1.939667e-02 9.113431e-05 4.018240e-03\n",
       "TCGA.HD.A4C1.01A 1.037395e-02 1.168693e-06 1.853892e-06 1.389217e-06\n",
       "TCGA.CV.7438.11A 1.094154e-03 6.450133e-03 1.981943e-04 2.369504e-04\n",
       "TCGA.CV.5444.01A 6.170893e-03 4.490983e-07 4.175766e-07 2.911519e-07\n",
       "TCGA.BA.5556.01A 2.534477e-02 1.919881e-02 9.241382e-04 3.625550e-06\n",
       "TCGA.P3.A6SX.01A 1.867874e-03 4.670143e-07 3.429470e-07 5.174869e-07\n",
       "TCGA.CV.7242.11A 4.594129e-03 2.158675e-03 2.730977e-05 1.801851e-06\n",
       "TCGA.DQ.7592.01A 5.765994e-03 9.210478e-04 8.855847e-07 1.131870e-03\n",
       "TCGA.CV.6937.01A 1.976317e-03 7.544563e-07 3.166395e-06 5.797741e-07\n",
       "TCGA.QK.A8ZB.01A 7.469520e-03 5.701797e-07 1.859023e-06 3.704592e-03\n",
       "TCGA.CV.7432.01A 5.137664e-03 3.056553e-07 1.084470e-06 1.401741e-06\n",
       "TCGA.CV.7089.01A 1.516107e-02 1.011682e-03 6.487607e-06 3.969543e-05\n",
       "TCGA.CV.6939.11A 3.375961e-02 2.043617e-06 2.373454e-07 1.717001e-07\n",
       "TCGA.BA.4075.01A 4.994196e-03 7.253185e-07 9.011630e-07 4.677923e-07\n",
       "TCGA.T3.A92M.01A 3.612272e-03 4.743024e-03 2.724614e-05 3.395150e-07\n",
       "⋮                ⋮            ⋮            ⋮            ⋮           \n",
       "TCGA.CV.7430.01A 6.533762e-03 1.229668e-06 1.957884e-06 2.408299e-04\n",
       "TCGA.D6.A74Q.01A 9.906454e-03 6.216704e-03 9.684231e-05 1.894224e-04\n",
       "TCGA.CV.7255.01A 1.916546e-02 5.195208e-07 4.008375e-07 1.231915e-06\n",
       "TCGA.CQ.6223.01A 2.129298e-06 1.415764e-05 5.436924e-06 1.792029e-03\n",
       "TCGA.CV.A460.01A 3.290758e-02 7.177306e-03 4.907335e-02 4.230033e-07\n",
       "TCGA.CV.7261.01A 1.813197e-02 8.235639e-07 3.138454e-06 2.912679e-06\n",
       "TCGA.CN.4736.01A 1.477365e-02 1.064861e-03 1.154187e-06 8.161323e-03\n",
       "TCGA.CR.7404.01A 4.256713e-02 1.856149e-02 5.986233e-03 2.059526e-07\n",
       "TCGA.UF.A719.01A 7.098415e-03 1.145896e-03 2.142360e-06 8.476798e-06\n",
       "TCGA.CV.7236.01A 2.895305e-02 5.283327e-07 3.139558e-06 6.894808e-07\n",
       "TCGA.CV.6951.01A 1.806717e-03 3.409096e-06 5.381342e-07 2.172331e-04\n",
       "TCGA.CN.4728.01A 7.897528e-03 3.288993e-07 5.028132e-07 3.106541e-07\n",
       "TCGA.CV.7090.01A 8.685670e-03 5.132976e-07 3.897865e-07 4.457247e-07\n",
       "TCGA.CV.5979.01A 6.916896e-03 8.838452e-07 1.062019e-06 4.597641e-07\n",
       "TCGA.CQ.7069.01A 2.126299e-02 4.895251e-07 8.017098e-07 4.783386e-07\n",
       "TCGA.CN.4733.01A 5.323205e-02 2.709184e-02 4.165599e-04 8.127728e-04\n",
       "TCGA.CR.7390.01A 3.353692e-03 3.534756e-07 3.580305e-07 3.245375e-07\n",
       "TCGA.CV.A45X.01A 9.429661e-04 2.044738e-06 7.332573e-06 1.879439e-05\n",
       "TCGA.IQ.A6SH.01A 4.988359e-03 1.400820e-03 7.230511e-07 8.482273e-07\n",
       "TCGA.CV.6962.11A 4.592181e-03 5.021691e-04 1.727208e-06 8.165269e-06\n",
       "TCGA.CV.6960.11A 7.602948e-03 8.251732e-07 1.291781e-06 1.550674e-06\n",
       "TCGA.CV.A464.01A 9.559703e-03 2.505905e-06 6.786841e-07 4.215465e-07\n",
       "TCGA.C9.A47Z.01A 1.350464e-05 7.509604e-07 1.323662e-06 2.687544e-02\n",
       "TCGA.CN.6010.01A 5.437399e-02 1.010305e-03 1.018232e-06 3.096677e-07\n",
       "TCGA.WA.A7GZ.11A 1.547518e-05 2.477334e-07 2.683054e-07 3.049265e-07\n",
       "TCGA.CV.7235.01A 1.429738e-02 3.535064e-03 1.016330e-05 2.956404e-07\n",
       "TCGA.CX.7086.01A 9.428269e-03 6.740519e-04 2.040884e-05 2.704299e-06\n",
       "TCGA.CV.6935.11A 9.079049e-03 1.706022e-04 9.964355e-07 7.419330e-05\n",
       "TCGA.P3.A6SW.01A 1.423648e-02 1.130333e-02 1.372259e-03 2.950967e-06\n",
       "TCGA.HD.A6HZ.01A 2.933271e-02 4.331431e-03 2.936404e-03 1.003798e-06"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "#final est cell type fraction in each bulk samples\n",
    "res$res$final.gibbs.thet"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 65,
   "id": "dc3ba074",
   "metadata": {},
   "outputs": [],
   "source": [
    "res$para"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 67,
   "id": "a355b99a",
   "metadata": {},
   "outputs": [],
   "source": [
    "res1 <- readRDS(\"/home/cke/BayesPrism/BP_PuramTCGA_res.rds\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 68,
   "id": "b4bd6fc0",
   "metadata": {
    "collapsed": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A matrix: 546 × 9 of type dbl</caption>\n",
       "<thead>\n",
       "\t<tr><th></th><th scope=col>tumor</th><th scope=col>Fibroblast</th><th scope=col>B cell</th><th scope=col>myocyte</th><th scope=col>Macrophage</th><th scope=col>Endothelial</th><th scope=col>T cell</th><th scope=col>Dendritic</th><th scope=col>Mast</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><th scope=row>TCGA.BB.4224.01A</th><td>0.8953963</td><td>3.295279e-03</td><td>1.535432e-07</td><td>2.076378e-03</td><td>2.663471e-06</td><td>1.099243e-06</td><td>2.711799e-07</td><td>4.547351e-07</td><td>9.922738e-02</td></tr>\n",
       "\t<tr><th scope=row>TCGA.H7.7774.01A</th><td>0.9807876</td><td>9.213523e-07</td><td>1.956431e-06</td><td>1.582816e-07</td><td>1.186069e-02</td><td>7.062818e-07</td><td>1.267113e-04</td><td>1.133469e-06</td><td>7.220150e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6943.01A</th><td>0.5239461</td><td>3.799039e-01</td><td>1.548700e-03</td><td>2.208963e-07</td><td>7.545321e-02</td><td>8.543457e-03</td><td>1.060355e-02</td><td>3.213430e-07</td><td>5.962804e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.5374.01A</th><td>0.8727039</td><td>2.463040e-02</td><td>6.619988e-03</td><td>6.413547e-03</td><td>2.021994e-02</td><td>2.152436e-02</td><td>2.999286e-02</td><td>1.789418e-02</td><td>8.044354e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.6227.01A</th><td>0.6538779</td><td>2.342006e-01</td><td>1.996756e-07</td><td>7.141557e-02</td><td>7.623701e-03</td><td>3.287952e-02</td><td>3.276224e-07</td><td>4.224889e-07</td><td>1.701781e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6959.01A</th><td>0.7848157</td><td>9.008879e-02</td><td>3.630708e-05</td><td>6.450137e-02</td><td>2.570535e-02</td><td>3.484607e-02</td><td>6.940279e-07</td><td>4.514340e-06</td><td>1.185480e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.F7.A61V.01A</th><td>0.9545372</td><td>1.147164e-02</td><td>1.391773e-03</td><td>2.241424e-02</td><td>4.397206e-03</td><td>5.219229e-03</td><td>5.633430e-04</td><td>4.516596e-06</td><td>8.426878e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7413.01A</th><td>0.7576784</td><td>2.165254e-01</td><td>1.947499e-07</td><td>8.478491e-08</td><td>2.579297e-02</td><td>4.341206e-07</td><td>1.038621e-06</td><td>2.309817e-07</td><td>1.216114e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7247.01A</th><td>0.7911627</td><td>1.108126e-01</td><td>1.374201e-07</td><td>7.858550e-02</td><td>6.057291e-07</td><td>1.943738e-02</td><td>1.658183e-07</td><td>6.054190e-07</td><td>2.752071e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.5249.01A</th><td>0.8287251</td><td>5.001096e-02</td><td>7.550117e-03</td><td>1.137713e-07</td><td>2.663733e-02</td><td>3.129438e-02</td><td>3.085065e-02</td><td>2.493104e-02</td><td>3.331009e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.5331.01A</th><td>0.8679074</td><td>3.680547e-02</td><td>6.729025e-04</td><td>6.492139e-08</td><td>6.722354e-02</td><td>2.205727e-02</td><td>5.329257e-03</td><td>3.620704e-06</td><td>4.945356e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.BB.8601.01A</th><td>0.9933812</td><td>4.261229e-03</td><td>7.357805e-05</td><td>2.507918e-07</td><td>3.730104e-06</td><td>2.237834e-03</td><td>1.768300e-06</td><td>2.015228e-06</td><td>3.842106e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45W.01A</th><td>0.7583385</td><td>9.038100e-02</td><td>4.573747e-02</td><td>2.842859e-07</td><td>5.930226e-02</td><td>3.803786e-02</td><td>5.694007e-03</td><td>2.508070e-03</td><td>5.767332e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.7063.01A</th><td>0.8932472</td><td>2.143019e-02</td><td>2.929627e-07</td><td>2.839658e-07</td><td>6.462695e-02</td><td>1.244862e-02</td><td>6.942133e-03</td><td>4.127833e-05</td><td>1.263061e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.5373.01A</th><td>0.7648254</td><td>1.857341e-01</td><td>3.306371e-07</td><td>6.088100e-04</td><td>2.179955e-02</td><td>4.760714e-06</td><td>7.257815e-07</td><td>8.311730e-07</td><td>2.702557e-02</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45T.01A</th><td>0.8189485</td><td>5.773553e-02</td><td>5.785000e-03</td><td>1.473200e-02</td><td>6.505784e-02</td><td>1.423510e-02</td><td>1.939667e-02</td><td>9.113431e-05</td><td>4.018240e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.HD.A4C1.01A</th><td>0.9037093</td><td>8.132439e-02</td><td>7.313362e-07</td><td>1.059151e-07</td><td>4.587139e-03</td><td>1.037395e-02</td><td>1.168693e-06</td><td>1.853892e-06</td><td>1.389217e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7438.11A</th><td>0.9736846</td><td>2.405088e-03</td><td>6.825740e-04</td><td>2.766721e-03</td><td>1.248155e-02</td><td>1.094154e-03</td><td>6.450133e-03</td><td>1.981943e-04</td><td>2.369504e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.5444.01A</th><td>0.4018990</td><td>5.008603e-01</td><td>1.421520e-07</td><td>3.634083e-02</td><td>5.472763e-02</td><td>6.170893e-03</td><td>4.490983e-07</td><td>4.175766e-07</td><td>2.911519e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.BA.5556.01A</th><td>0.8490606</td><td>4.796692e-02</td><td>2.149780e-05</td><td>9.793571e-08</td><td>5.747951e-02</td><td>2.534477e-02</td><td>1.919881e-02</td><td>9.241382e-04</td><td>3.625550e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.P3.A6SX.01A</th><td>0.8960362</td><td>9.110862e-02</td><td>1.878011e-07</td><td>1.098512e-02</td><td>6.988049e-07</td><td>1.867874e-03</td><td>4.670143e-07</td><td>3.429470e-07</td><td>5.174869e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7242.11A</th><td>0.9755767</td><td>5.311162e-03</td><td>3.153993e-05</td><td>3.141680e-07</td><td>1.229840e-02</td><td>4.594129e-03</td><td>2.158675e-03</td><td>2.730977e-05</td><td>1.801851e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.DQ.7592.01A</th><td>0.8323528</td><td>1.342008e-01</td><td>1.722611e-07</td><td>1.280968e-02</td><td>1.281682e-02</td><td>5.765994e-03</td><td>9.210478e-04</td><td>8.855847e-07</td><td>1.131870e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6937.01A</th><td>0.8360634</td><td>1.441721e-01</td><td>3.585737e-07</td><td>4.275409e-07</td><td>1.778293e-02</td><td>1.976317e-03</td><td>7.544563e-07</td><td>3.166395e-06</td><td>5.797741e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.QK.A8ZB.01A</th><td>0.8499897</td><td>1.257516e-01</td><td>6.130647e-03</td><td>1.031490e-07</td><td>6.951394e-03</td><td>7.469520e-03</td><td>5.701797e-07</td><td>1.859023e-06</td><td>3.704592e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7432.01A</th><td>0.9688731</td><td>2.165490e-02</td><td>1.442955e-07</td><td>1.739435e-07</td><td>4.331192e-03</td><td>5.137664e-03</td><td>3.056553e-07</td><td>1.084470e-06</td><td>1.401741e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7089.01A</th><td>0.9668070</td><td>8.355609e-03</td><td>2.990496e-07</td><td>1.403883e-07</td><td>8.618054e-03</td><td>1.516107e-02</td><td>1.011682e-03</td><td>6.487607e-06</td><td>3.969543e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6939.11A</th><td>0.3108183</td><td>2.925750e-02</td><td>1.597606e-03</td><td>6.230553e-01</td><td>1.509185e-03</td><td>3.375961e-02</td><td>2.043617e-06</td><td>2.373454e-07</td><td>1.717001e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.BA.4075.01A</th><td>0.9198085</td><td>4.745561e-02</td><td>3.472322e-07</td><td>2.176400e-03</td><td>2.556290e-02</td><td>4.994196e-03</td><td>7.253185e-07</td><td>9.011630e-07</td><td>4.677923e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.T3.A92M.01A</th><td>0.6663292</td><td>2.896026e-01</td><td>1.676743e-03</td><td>1.417736e-07</td><td>3.400842e-02</td><td>3.612272e-03</td><td>4.743024e-03</td><td>2.724614e-05</td><td>3.395150e-07</td></tr>\n",
       "\t<tr><th scope=row>⋮</th><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7430.01A</th><td>0.9774183</td><td>0.015130849</td><td>3.765206e-07</td><td>1.369697e-07</td><td>6.725784e-04</td><td>6.533762e-03</td><td>1.229668e-06</td><td>1.957884e-06</td><td>2.408299e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.D6.A74Q.01A</th><td>0.8842049</td><td>0.085482558</td><td>6.163754e-03</td><td>1.556808e-07</td><td>7.739195e-03</td><td>9.906454e-03</td><td>6.216704e-03</td><td>9.684231e-05</td><td>1.894224e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7255.01A</th><td>0.9440443</td><td>0.027434705</td><td>2.563307e-07</td><td>9.352016e-03</td><td>1.086210e-06</td><td>1.916546e-02</td><td>5.195208e-07</td><td>4.008375e-07</td><td>1.231915e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.6223.01A</th><td>0.9781348</td><td>0.006737177</td><td>3.301923e-04</td><td>1.067407e-07</td><td>1.298400e-02</td><td>2.129298e-06</td><td>1.415764e-05</td><td>5.436924e-06</td><td>1.792029e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A460.01A</th><td>0.7211691</td><td>0.150885458</td><td>2.310984e-03</td><td>1.378379e-07</td><td>3.647569e-02</td><td>3.290758e-02</td><td>7.177306e-03</td><td>4.907335e-02</td><td>4.230033e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7261.01A</th><td>0.7686271</td><td>0.199999998</td><td>1.800759e-03</td><td>1.830788e-07</td><td>1.143315e-02</td><td>1.813197e-02</td><td>8.235639e-07</td><td>3.138454e-06</td><td>2.912679e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4736.01A</th><td>0.5770123</td><td>0.202003425</td><td>3.214170e-07</td><td>1.087496e-01</td><td>8.823329e-02</td><td>1.477365e-02</td><td>1.064861e-03</td><td>1.154187e-06</td><td>8.161323e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.7404.01A</th><td>0.8335180</td><td>0.049152821</td><td>5.844858e-03</td><td>1.735372e-07</td><td>4.436907e-02</td><td>4.256713e-02</td><td>1.856149e-02</td><td>5.986233e-03</td><td>2.059526e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.UF.A719.01A</th><td>0.9767740</td><td>0.009284403</td><td>1.501744e-05</td><td>6.696999e-07</td><td>5.670974e-03</td><td>7.098415e-03</td><td>1.145896e-03</td><td>2.142360e-06</td><td>8.476798e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7236.01A</th><td>0.7583639</td><td>0.201827735</td><td>3.707119e-07</td><td>7.813978e-08</td><td>1.085050e-02</td><td>2.895305e-02</td><td>5.283327e-07</td><td>3.139558e-06</td><td>6.894808e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6951.01A</th><td>0.9146561</td><td>0.059564714</td><td>4.368603e-07</td><td>2.203449e-02</td><td>1.716345e-03</td><td>1.806717e-03</td><td>3.409096e-06</td><td>5.381342e-07</td><td>2.172331e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4728.01A</th><td>0.2860686</td><td>0.608054579</td><td>2.411349e-07</td><td>5.917761e-03</td><td>9.206015e-02</td><td>7.897528e-03</td><td>3.288993e-07</td><td>5.028132e-07</td><td>3.106541e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7090.01A</th><td>0.7096929</td><td>0.227983815</td><td>1.494937e-07</td><td>1.164804e-07</td><td>5.363601e-02</td><td>8.685670e-03</td><td>5.132976e-07</td><td>3.897865e-07</td><td>4.457247e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.5979.01A</th><td>0.9170363</td><td>0.069411556</td><td>2.913286e-07</td><td>1.650445e-03</td><td>4.982065e-03</td><td>6.916896e-03</td><td>8.838452e-07</td><td>1.062019e-06</td><td>4.597641e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.7069.01A</th><td>0.8867397</td><td>0.091163538</td><td>3.126233e-07</td><td>1.693463e-07</td><td>8.315407e-04</td><td>2.126299e-02</td><td>4.895251e-07</td><td>8.017098e-07</td><td>4.783386e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4733.01A</th><td>0.4590225</td><td>0.313208243</td><td>2.204239e-02</td><td>1.200962e-02</td><td>1.121640e-01</td><td>5.323205e-02</td><td>2.709184e-02</td><td>4.165599e-04</td><td>8.127728e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.7390.01A</th><td>0.8226924</td><td>0.170653482</td><td>1.782093e-07</td><td>1.786800e-07</td><td>3.298995e-03</td><td>3.353692e-03</td><td>3.534756e-07</td><td>3.580305e-07</td><td>3.245375e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45X.01A</th><td>0.9860628</td><td>0.005683827</td><td>8.349780e-07</td><td>3.304159e-07</td><td>7.281100e-03</td><td>9.429661e-04</td><td>2.044738e-06</td><td>7.332573e-06</td><td>1.879439e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.IQ.A6SH.01A</th><td>0.9423716</td><td>0.028385095</td><td>1.185881e-06</td><td>2.116455e-07</td><td>2.285112e-02</td><td>4.988359e-03</td><td>1.400820e-03</td><td>7.230511e-07</td><td>8.482273e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6962.11A</th><td>0.9723949</td><td>0.018871943</td><td>1.635403e-04</td><td>3.305504e-07</td><td>3.465067e-03</td><td>4.592181e-03</td><td>5.021691e-04</td><td>1.727208e-06</td><td>8.165269e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6960.11A</th><td>0.9791954</td><td>0.004831106</td><td>3.776268e-07</td><td>3.209457e-06</td><td>8.363308e-03</td><td>7.602948e-03</td><td>8.251732e-07</td><td>1.291781e-06</td><td>1.550674e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A464.01A</th><td>0.6267057</td><td>0.311161624</td><td>3.606024e-07</td><td>4.331322e-02</td><td>9.255807e-03</td><td>9.559703e-03</td><td>2.505905e-06</td><td>6.786841e-07</td><td>4.215465e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.C9.A47Z.01A</th><td>0.9654155</td><td>0.004341460</td><td>3.396085e-07</td><td>3.333502e-03</td><td>1.816612e-05</td><td>1.350464e-05</td><td>7.509604e-07</td><td>1.323662e-06</td><td>2.687544e-02</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.6010.01A</th><td>0.8331282</td><td>0.090147619</td><td>1.197741e-02</td><td>2.411752e-04</td><td>9.119946e-03</td><td>5.437399e-02</td><td>1.010305e-03</td><td>1.018232e-06</td><td>3.096677e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.WA.A7GZ.11A</th><td>0.5235703</td><td>0.003300802</td><td>1.269879e-07</td><td>4.731121e-01</td><td>3.789888e-07</td><td>1.547518e-05</td><td>2.477334e-07</td><td>2.683054e-07</td><td>3.049265e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7235.01A</th><td>0.6329990</td><td>0.323112422</td><td>1.914870e-07</td><td>9.378561e-08</td><td>2.604538e-02</td><td>1.429738e-02</td><td>3.535064e-03</td><td>1.016330e-05</td><td>2.956404e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CX.7086.01A</th><td>0.9751108</td><td>0.006095150</td><td>2.551141e-04</td><td>6.397217e-07</td><td>8.412847e-03</td><td>9.428269e-03</td><td>6.740519e-04</td><td>2.040884e-05</td><td>2.704299e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6935.11A</th><td>0.9811203</td><td>0.001239664</td><td>1.559001e-06</td><td>2.865151e-07</td><td>8.313372e-03</td><td>9.079049e-03</td><td>1.706022e-04</td><td>9.964355e-07</td><td>7.419330e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.P3.A6SW.01A</th><td>0.8650169</td><td>0.055371537</td><td>1.725337e-02</td><td>2.161523e-07</td><td>3.544294e-02</td><td>1.423648e-02</td><td>1.130333e-02</td><td>1.372259e-03</td><td>2.950967e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.HD.A6HZ.01A</th><td>0.7502374</td><td>0.116762381</td><td>8.185442e-03</td><td>3.767268e-02</td><td>5.054054e-02</td><td>2.933271e-02</td><td>4.331431e-03</td><td>2.936404e-03</td><td>1.003798e-06</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A matrix: 546 × 9 of type dbl\n",
       "\\begin{tabular}{r|lllllllll}\n",
       "  & tumor & Fibroblast & B cell & myocyte & Macrophage & Endothelial & T cell & Dendritic & Mast\\\\\n",
       "\\hline\n",
       "\tTCGA.BB.4224.01A & 0.8953963 & 3.295279e-03 & 1.535432e-07 & 2.076378e-03 & 2.663471e-06 & 1.099243e-06 & 2.711799e-07 & 4.547351e-07 & 9.922738e-02\\\\\n",
       "\tTCGA.H7.7774.01A & 0.9807876 & 9.213523e-07 & 1.956431e-06 & 1.582816e-07 & 1.186069e-02 & 7.062818e-07 & 1.267113e-04 & 1.133469e-06 & 7.220150e-03\\\\\n",
       "\tTCGA.CV.6943.01A & 0.5239461 & 3.799039e-01 & 1.548700e-03 & 2.208963e-07 & 7.545321e-02 & 8.543457e-03 & 1.060355e-02 & 3.213430e-07 & 5.962804e-07\\\\\n",
       "\tTCGA.CN.5374.01A & 0.8727039 & 2.463040e-02 & 6.619988e-03 & 6.413547e-03 & 2.021994e-02 & 2.152436e-02 & 2.999286e-02 & 1.789418e-02 & 8.044354e-07\\\\\n",
       "\tTCGA.CQ.6227.01A & 0.6538779 & 2.342006e-01 & 1.996756e-07 & 7.141557e-02 & 7.623701e-03 & 3.287952e-02 & 3.276224e-07 & 4.224889e-07 & 1.701781e-06\\\\\n",
       "\tTCGA.CV.6959.01A & 0.7848157 & 9.008879e-02 & 3.630708e-05 & 6.450137e-02 & 2.570535e-02 & 3.484607e-02 & 6.940279e-07 & 4.514340e-06 & 1.185480e-06\\\\\n",
       "\tTCGA.F7.A61V.01A & 0.9545372 & 1.147164e-02 & 1.391773e-03 & 2.241424e-02 & 4.397206e-03 & 5.219229e-03 & 5.633430e-04 & 4.516596e-06 & 8.426878e-07\\\\\n",
       "\tTCGA.CV.7413.01A & 0.7576784 & 2.165254e-01 & 1.947499e-07 & 8.478491e-08 & 2.579297e-02 & 4.341206e-07 & 1.038621e-06 & 2.309817e-07 & 1.216114e-06\\\\\n",
       "\tTCGA.CV.7247.01A & 0.7911627 & 1.108126e-01 & 1.374201e-07 & 7.858550e-02 & 6.057291e-07 & 1.943738e-02 & 1.658183e-07 & 6.054190e-07 & 2.752071e-07\\\\\n",
       "\tTCGA.CR.5249.01A & 0.8287251 & 5.001096e-02 & 7.550117e-03 & 1.137713e-07 & 2.663733e-02 & 3.129438e-02 & 3.085065e-02 & 2.493104e-02 & 3.331009e-07\\\\\n",
       "\tTCGA.CQ.5331.01A & 0.8679074 & 3.680547e-02 & 6.729025e-04 & 6.492139e-08 & 6.722354e-02 & 2.205727e-02 & 5.329257e-03 & 3.620704e-06 & 4.945356e-07\\\\\n",
       "\tTCGA.BB.8601.01A & 0.9933812 & 4.261229e-03 & 7.357805e-05 & 2.507918e-07 & 3.730104e-06 & 2.237834e-03 & 1.768300e-06 & 2.015228e-06 & 3.842106e-05\\\\\n",
       "\tTCGA.CV.A45W.01A & 0.7583385 & 9.038100e-02 & 4.573747e-02 & 2.842859e-07 & 5.930226e-02 & 3.803786e-02 & 5.694007e-03 & 2.508070e-03 & 5.767332e-07\\\\\n",
       "\tTCGA.CQ.7063.01A & 0.8932472 & 2.143019e-02 & 2.929627e-07 & 2.839658e-07 & 6.462695e-02 & 1.244862e-02 & 6.942133e-03 & 4.127833e-05 & 1.263061e-03\\\\\n",
       "\tTCGA.CN.5373.01A & 0.7648254 & 1.857341e-01 & 3.306371e-07 & 6.088100e-04 & 2.179955e-02 & 4.760714e-06 & 7.257815e-07 & 8.311730e-07 & 2.702557e-02\\\\\n",
       "\tTCGA.CV.A45T.01A & 0.8189485 & 5.773553e-02 & 5.785000e-03 & 1.473200e-02 & 6.505784e-02 & 1.423510e-02 & 1.939667e-02 & 9.113431e-05 & 4.018240e-03\\\\\n",
       "\tTCGA.HD.A4C1.01A & 0.9037093 & 8.132439e-02 & 7.313362e-07 & 1.059151e-07 & 4.587139e-03 & 1.037395e-02 & 1.168693e-06 & 1.853892e-06 & 1.389217e-06\\\\\n",
       "\tTCGA.CV.7438.11A & 0.9736846 & 2.405088e-03 & 6.825740e-04 & 2.766721e-03 & 1.248155e-02 & 1.094154e-03 & 6.450133e-03 & 1.981943e-04 & 2.369504e-04\\\\\n",
       "\tTCGA.CV.5444.01A & 0.4018990 & 5.008603e-01 & 1.421520e-07 & 3.634083e-02 & 5.472763e-02 & 6.170893e-03 & 4.490983e-07 & 4.175766e-07 & 2.911519e-07\\\\\n",
       "\tTCGA.BA.5556.01A & 0.8490606 & 4.796692e-02 & 2.149780e-05 & 9.793571e-08 & 5.747951e-02 & 2.534477e-02 & 1.919881e-02 & 9.241382e-04 & 3.625550e-06\\\\\n",
       "\tTCGA.P3.A6SX.01A & 0.8960362 & 9.110862e-02 & 1.878011e-07 & 1.098512e-02 & 6.988049e-07 & 1.867874e-03 & 4.670143e-07 & 3.429470e-07 & 5.174869e-07\\\\\n",
       "\tTCGA.CV.7242.11A & 0.9755767 & 5.311162e-03 & 3.153993e-05 & 3.141680e-07 & 1.229840e-02 & 4.594129e-03 & 2.158675e-03 & 2.730977e-05 & 1.801851e-06\\\\\n",
       "\tTCGA.DQ.7592.01A & 0.8323528 & 1.342008e-01 & 1.722611e-07 & 1.280968e-02 & 1.281682e-02 & 5.765994e-03 & 9.210478e-04 & 8.855847e-07 & 1.131870e-03\\\\\n",
       "\tTCGA.CV.6937.01A & 0.8360634 & 1.441721e-01 & 3.585737e-07 & 4.275409e-07 & 1.778293e-02 & 1.976317e-03 & 7.544563e-07 & 3.166395e-06 & 5.797741e-07\\\\\n",
       "\tTCGA.QK.A8ZB.01A & 0.8499897 & 1.257516e-01 & 6.130647e-03 & 1.031490e-07 & 6.951394e-03 & 7.469520e-03 & 5.701797e-07 & 1.859023e-06 & 3.704592e-03\\\\\n",
       "\tTCGA.CV.7432.01A & 0.9688731 & 2.165490e-02 & 1.442955e-07 & 1.739435e-07 & 4.331192e-03 & 5.137664e-03 & 3.056553e-07 & 1.084470e-06 & 1.401741e-06\\\\\n",
       "\tTCGA.CV.7089.01A & 0.9668070 & 8.355609e-03 & 2.990496e-07 & 1.403883e-07 & 8.618054e-03 & 1.516107e-02 & 1.011682e-03 & 6.487607e-06 & 3.969543e-05\\\\\n",
       "\tTCGA.CV.6939.11A & 0.3108183 & 2.925750e-02 & 1.597606e-03 & 6.230553e-01 & 1.509185e-03 & 3.375961e-02 & 2.043617e-06 & 2.373454e-07 & 1.717001e-07\\\\\n",
       "\tTCGA.BA.4075.01A & 0.9198085 & 4.745561e-02 & 3.472322e-07 & 2.176400e-03 & 2.556290e-02 & 4.994196e-03 & 7.253185e-07 & 9.011630e-07 & 4.677923e-07\\\\\n",
       "\tTCGA.T3.A92M.01A & 0.6663292 & 2.896026e-01 & 1.676743e-03 & 1.417736e-07 & 3.400842e-02 & 3.612272e-03 & 4.743024e-03 & 2.724614e-05 & 3.395150e-07\\\\\n",
       "\t⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n",
       "\tTCGA.CV.7430.01A & 0.9774183 & 0.015130849 & 3.765206e-07 & 1.369697e-07 & 6.725784e-04 & 6.533762e-03 & 1.229668e-06 & 1.957884e-06 & 2.408299e-04\\\\\n",
       "\tTCGA.D6.A74Q.01A & 0.8842049 & 0.085482558 & 6.163754e-03 & 1.556808e-07 & 7.739195e-03 & 9.906454e-03 & 6.216704e-03 & 9.684231e-05 & 1.894224e-04\\\\\n",
       "\tTCGA.CV.7255.01A & 0.9440443 & 0.027434705 & 2.563307e-07 & 9.352016e-03 & 1.086210e-06 & 1.916546e-02 & 5.195208e-07 & 4.008375e-07 & 1.231915e-06\\\\\n",
       "\tTCGA.CQ.6223.01A & 0.9781348 & 0.006737177 & 3.301923e-04 & 1.067407e-07 & 1.298400e-02 & 2.129298e-06 & 1.415764e-05 & 5.436924e-06 & 1.792029e-03\\\\\n",
       "\tTCGA.CV.A460.01A & 0.7211691 & 0.150885458 & 2.310984e-03 & 1.378379e-07 & 3.647569e-02 & 3.290758e-02 & 7.177306e-03 & 4.907335e-02 & 4.230033e-07\\\\\n",
       "\tTCGA.CV.7261.01A & 0.7686271 & 0.199999998 & 1.800759e-03 & 1.830788e-07 & 1.143315e-02 & 1.813197e-02 & 8.235639e-07 & 3.138454e-06 & 2.912679e-06\\\\\n",
       "\tTCGA.CN.4736.01A & 0.5770123 & 0.202003425 & 3.214170e-07 & 1.087496e-01 & 8.823329e-02 & 1.477365e-02 & 1.064861e-03 & 1.154187e-06 & 8.161323e-03\\\\\n",
       "\tTCGA.CR.7404.01A & 0.8335180 & 0.049152821 & 5.844858e-03 & 1.735372e-07 & 4.436907e-02 & 4.256713e-02 & 1.856149e-02 & 5.986233e-03 & 2.059526e-07\\\\\n",
       "\tTCGA.UF.A719.01A & 0.9767740 & 0.009284403 & 1.501744e-05 & 6.696999e-07 & 5.670974e-03 & 7.098415e-03 & 1.145896e-03 & 2.142360e-06 & 8.476798e-06\\\\\n",
       "\tTCGA.CV.7236.01A & 0.7583639 & 0.201827735 & 3.707119e-07 & 7.813978e-08 & 1.085050e-02 & 2.895305e-02 & 5.283327e-07 & 3.139558e-06 & 6.894808e-07\\\\\n",
       "\tTCGA.CV.6951.01A & 0.9146561 & 0.059564714 & 4.368603e-07 & 2.203449e-02 & 1.716345e-03 & 1.806717e-03 & 3.409096e-06 & 5.381342e-07 & 2.172331e-04\\\\\n",
       "\tTCGA.CN.4728.01A & 0.2860686 & 0.608054579 & 2.411349e-07 & 5.917761e-03 & 9.206015e-02 & 7.897528e-03 & 3.288993e-07 & 5.028132e-07 & 3.106541e-07\\\\\n",
       "\tTCGA.CV.7090.01A & 0.7096929 & 0.227983815 & 1.494937e-07 & 1.164804e-07 & 5.363601e-02 & 8.685670e-03 & 5.132976e-07 & 3.897865e-07 & 4.457247e-07\\\\\n",
       "\tTCGA.CV.5979.01A & 0.9170363 & 0.069411556 & 2.913286e-07 & 1.650445e-03 & 4.982065e-03 & 6.916896e-03 & 8.838452e-07 & 1.062019e-06 & 4.597641e-07\\\\\n",
       "\tTCGA.CQ.7069.01A & 0.8867397 & 0.091163538 & 3.126233e-07 & 1.693463e-07 & 8.315407e-04 & 2.126299e-02 & 4.895251e-07 & 8.017098e-07 & 4.783386e-07\\\\\n",
       "\tTCGA.CN.4733.01A & 0.4590225 & 0.313208243 & 2.204239e-02 & 1.200962e-02 & 1.121640e-01 & 5.323205e-02 & 2.709184e-02 & 4.165599e-04 & 8.127728e-04\\\\\n",
       "\tTCGA.CR.7390.01A & 0.8226924 & 0.170653482 & 1.782093e-07 & 1.786800e-07 & 3.298995e-03 & 3.353692e-03 & 3.534756e-07 & 3.580305e-07 & 3.245375e-07\\\\\n",
       "\tTCGA.CV.A45X.01A & 0.9860628 & 0.005683827 & 8.349780e-07 & 3.304159e-07 & 7.281100e-03 & 9.429661e-04 & 2.044738e-06 & 7.332573e-06 & 1.879439e-05\\\\\n",
       "\tTCGA.IQ.A6SH.01A & 0.9423716 & 0.028385095 & 1.185881e-06 & 2.116455e-07 & 2.285112e-02 & 4.988359e-03 & 1.400820e-03 & 7.230511e-07 & 8.482273e-07\\\\\n",
       "\tTCGA.CV.6962.11A & 0.9723949 & 0.018871943 & 1.635403e-04 & 3.305504e-07 & 3.465067e-03 & 4.592181e-03 & 5.021691e-04 & 1.727208e-06 & 8.165269e-06\\\\\n",
       "\tTCGA.CV.6960.11A & 0.9791954 & 0.004831106 & 3.776268e-07 & 3.209457e-06 & 8.363308e-03 & 7.602948e-03 & 8.251732e-07 & 1.291781e-06 & 1.550674e-06\\\\\n",
       "\tTCGA.CV.A464.01A & 0.6267057 & 0.311161624 & 3.606024e-07 & 4.331322e-02 & 9.255807e-03 & 9.559703e-03 & 2.505905e-06 & 6.786841e-07 & 4.215465e-07\\\\\n",
       "\tTCGA.C9.A47Z.01A & 0.9654155 & 0.004341460 & 3.396085e-07 & 3.333502e-03 & 1.816612e-05 & 1.350464e-05 & 7.509604e-07 & 1.323662e-06 & 2.687544e-02\\\\\n",
       "\tTCGA.CN.6010.01A & 0.8331282 & 0.090147619 & 1.197741e-02 & 2.411752e-04 & 9.119946e-03 & 5.437399e-02 & 1.010305e-03 & 1.018232e-06 & 3.096677e-07\\\\\n",
       "\tTCGA.WA.A7GZ.11A & 0.5235703 & 0.003300802 & 1.269879e-07 & 4.731121e-01 & 3.789888e-07 & 1.547518e-05 & 2.477334e-07 & 2.683054e-07 & 3.049265e-07\\\\\n",
       "\tTCGA.CV.7235.01A & 0.6329990 & 0.323112422 & 1.914870e-07 & 9.378561e-08 & 2.604538e-02 & 1.429738e-02 & 3.535064e-03 & 1.016330e-05 & 2.956404e-07\\\\\n",
       "\tTCGA.CX.7086.01A & 0.9751108 & 0.006095150 & 2.551141e-04 & 6.397217e-07 & 8.412847e-03 & 9.428269e-03 & 6.740519e-04 & 2.040884e-05 & 2.704299e-06\\\\\n",
       "\tTCGA.CV.6935.11A & 0.9811203 & 0.001239664 & 1.559001e-06 & 2.865151e-07 & 8.313372e-03 & 9.079049e-03 & 1.706022e-04 & 9.964355e-07 & 7.419330e-05\\\\\n",
       "\tTCGA.P3.A6SW.01A & 0.8650169 & 0.055371537 & 1.725337e-02 & 2.161523e-07 & 3.544294e-02 & 1.423648e-02 & 1.130333e-02 & 1.372259e-03 & 2.950967e-06\\\\\n",
       "\tTCGA.HD.A6HZ.01A & 0.7502374 & 0.116762381 & 8.185442e-03 & 3.767268e-02 & 5.054054e-02 & 2.933271e-02 & 4.331431e-03 & 2.936404e-03 & 1.003798e-06\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A matrix: 546 × 9 of type dbl\n",
       "\n",
       "| <!--/--> | tumor | Fibroblast | B cell | myocyte | Macrophage | Endothelial | T cell | Dendritic | Mast |\n",
       "|---|---|---|---|---|---|---|---|---|---|\n",
       "| TCGA.BB.4224.01A | 0.8953963 | 3.295279e-03 | 1.535432e-07 | 2.076378e-03 | 2.663471e-06 | 1.099243e-06 | 2.711799e-07 | 4.547351e-07 | 9.922738e-02 |\n",
       "| TCGA.H7.7774.01A | 0.9807876 | 9.213523e-07 | 1.956431e-06 | 1.582816e-07 | 1.186069e-02 | 7.062818e-07 | 1.267113e-04 | 1.133469e-06 | 7.220150e-03 |\n",
       "| TCGA.CV.6943.01A | 0.5239461 | 3.799039e-01 | 1.548700e-03 | 2.208963e-07 | 7.545321e-02 | 8.543457e-03 | 1.060355e-02 | 3.213430e-07 | 5.962804e-07 |\n",
       "| TCGA.CN.5374.01A | 0.8727039 | 2.463040e-02 | 6.619988e-03 | 6.413547e-03 | 2.021994e-02 | 2.152436e-02 | 2.999286e-02 | 1.789418e-02 | 8.044354e-07 |\n",
       "| TCGA.CQ.6227.01A | 0.6538779 | 2.342006e-01 | 1.996756e-07 | 7.141557e-02 | 7.623701e-03 | 3.287952e-02 | 3.276224e-07 | 4.224889e-07 | 1.701781e-06 |\n",
       "| TCGA.CV.6959.01A | 0.7848157 | 9.008879e-02 | 3.630708e-05 | 6.450137e-02 | 2.570535e-02 | 3.484607e-02 | 6.940279e-07 | 4.514340e-06 | 1.185480e-06 |\n",
       "| TCGA.F7.A61V.01A | 0.9545372 | 1.147164e-02 | 1.391773e-03 | 2.241424e-02 | 4.397206e-03 | 5.219229e-03 | 5.633430e-04 | 4.516596e-06 | 8.426878e-07 |\n",
       "| TCGA.CV.7413.01A | 0.7576784 | 2.165254e-01 | 1.947499e-07 | 8.478491e-08 | 2.579297e-02 | 4.341206e-07 | 1.038621e-06 | 2.309817e-07 | 1.216114e-06 |\n",
       "| TCGA.CV.7247.01A | 0.7911627 | 1.108126e-01 | 1.374201e-07 | 7.858550e-02 | 6.057291e-07 | 1.943738e-02 | 1.658183e-07 | 6.054190e-07 | 2.752071e-07 |\n",
       "| TCGA.CR.5249.01A | 0.8287251 | 5.001096e-02 | 7.550117e-03 | 1.137713e-07 | 2.663733e-02 | 3.129438e-02 | 3.085065e-02 | 2.493104e-02 | 3.331009e-07 |\n",
       "| TCGA.CQ.5331.01A | 0.8679074 | 3.680547e-02 | 6.729025e-04 | 6.492139e-08 | 6.722354e-02 | 2.205727e-02 | 5.329257e-03 | 3.620704e-06 | 4.945356e-07 |\n",
       "| TCGA.BB.8601.01A | 0.9933812 | 4.261229e-03 | 7.357805e-05 | 2.507918e-07 | 3.730104e-06 | 2.237834e-03 | 1.768300e-06 | 2.015228e-06 | 3.842106e-05 |\n",
       "| TCGA.CV.A45W.01A | 0.7583385 | 9.038100e-02 | 4.573747e-02 | 2.842859e-07 | 5.930226e-02 | 3.803786e-02 | 5.694007e-03 | 2.508070e-03 | 5.767332e-07 |\n",
       "| TCGA.CQ.7063.01A | 0.8932472 | 2.143019e-02 | 2.929627e-07 | 2.839658e-07 | 6.462695e-02 | 1.244862e-02 | 6.942133e-03 | 4.127833e-05 | 1.263061e-03 |\n",
       "| TCGA.CN.5373.01A | 0.7648254 | 1.857341e-01 | 3.306371e-07 | 6.088100e-04 | 2.179955e-02 | 4.760714e-06 | 7.257815e-07 | 8.311730e-07 | 2.702557e-02 |\n",
       "| TCGA.CV.A45T.01A | 0.8189485 | 5.773553e-02 | 5.785000e-03 | 1.473200e-02 | 6.505784e-02 | 1.423510e-02 | 1.939667e-02 | 9.113431e-05 | 4.018240e-03 |\n",
       "| TCGA.HD.A4C1.01A | 0.9037093 | 8.132439e-02 | 7.313362e-07 | 1.059151e-07 | 4.587139e-03 | 1.037395e-02 | 1.168693e-06 | 1.853892e-06 | 1.389217e-06 |\n",
       "| TCGA.CV.7438.11A | 0.9736846 | 2.405088e-03 | 6.825740e-04 | 2.766721e-03 | 1.248155e-02 | 1.094154e-03 | 6.450133e-03 | 1.981943e-04 | 2.369504e-04 |\n",
       "| TCGA.CV.5444.01A | 0.4018990 | 5.008603e-01 | 1.421520e-07 | 3.634083e-02 | 5.472763e-02 | 6.170893e-03 | 4.490983e-07 | 4.175766e-07 | 2.911519e-07 |\n",
       "| TCGA.BA.5556.01A | 0.8490606 | 4.796692e-02 | 2.149780e-05 | 9.793571e-08 | 5.747951e-02 | 2.534477e-02 | 1.919881e-02 | 9.241382e-04 | 3.625550e-06 |\n",
       "| TCGA.P3.A6SX.01A | 0.8960362 | 9.110862e-02 | 1.878011e-07 | 1.098512e-02 | 6.988049e-07 | 1.867874e-03 | 4.670143e-07 | 3.429470e-07 | 5.174869e-07 |\n",
       "| TCGA.CV.7242.11A | 0.9755767 | 5.311162e-03 | 3.153993e-05 | 3.141680e-07 | 1.229840e-02 | 4.594129e-03 | 2.158675e-03 | 2.730977e-05 | 1.801851e-06 |\n",
       "| TCGA.DQ.7592.01A | 0.8323528 | 1.342008e-01 | 1.722611e-07 | 1.280968e-02 | 1.281682e-02 | 5.765994e-03 | 9.210478e-04 | 8.855847e-07 | 1.131870e-03 |\n",
       "| TCGA.CV.6937.01A | 0.8360634 | 1.441721e-01 | 3.585737e-07 | 4.275409e-07 | 1.778293e-02 | 1.976317e-03 | 7.544563e-07 | 3.166395e-06 | 5.797741e-07 |\n",
       "| TCGA.QK.A8ZB.01A | 0.8499897 | 1.257516e-01 | 6.130647e-03 | 1.031490e-07 | 6.951394e-03 | 7.469520e-03 | 5.701797e-07 | 1.859023e-06 | 3.704592e-03 |\n",
       "| TCGA.CV.7432.01A | 0.9688731 | 2.165490e-02 | 1.442955e-07 | 1.739435e-07 | 4.331192e-03 | 5.137664e-03 | 3.056553e-07 | 1.084470e-06 | 1.401741e-06 |\n",
       "| TCGA.CV.7089.01A | 0.9668070 | 8.355609e-03 | 2.990496e-07 | 1.403883e-07 | 8.618054e-03 | 1.516107e-02 | 1.011682e-03 | 6.487607e-06 | 3.969543e-05 |\n",
       "| TCGA.CV.6939.11A | 0.3108183 | 2.925750e-02 | 1.597606e-03 | 6.230553e-01 | 1.509185e-03 | 3.375961e-02 | 2.043617e-06 | 2.373454e-07 | 1.717001e-07 |\n",
       "| TCGA.BA.4075.01A | 0.9198085 | 4.745561e-02 | 3.472322e-07 | 2.176400e-03 | 2.556290e-02 | 4.994196e-03 | 7.253185e-07 | 9.011630e-07 | 4.677923e-07 |\n",
       "| TCGA.T3.A92M.01A | 0.6663292 | 2.896026e-01 | 1.676743e-03 | 1.417736e-07 | 3.400842e-02 | 3.612272e-03 | 4.743024e-03 | 2.724614e-05 | 3.395150e-07 |\n",
       "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ |\n",
       "| TCGA.CV.7430.01A | 0.9774183 | 0.015130849 | 3.765206e-07 | 1.369697e-07 | 6.725784e-04 | 6.533762e-03 | 1.229668e-06 | 1.957884e-06 | 2.408299e-04 |\n",
       "| TCGA.D6.A74Q.01A | 0.8842049 | 0.085482558 | 6.163754e-03 | 1.556808e-07 | 7.739195e-03 | 9.906454e-03 | 6.216704e-03 | 9.684231e-05 | 1.894224e-04 |\n",
       "| TCGA.CV.7255.01A | 0.9440443 | 0.027434705 | 2.563307e-07 | 9.352016e-03 | 1.086210e-06 | 1.916546e-02 | 5.195208e-07 | 4.008375e-07 | 1.231915e-06 |\n",
       "| TCGA.CQ.6223.01A | 0.9781348 | 0.006737177 | 3.301923e-04 | 1.067407e-07 | 1.298400e-02 | 2.129298e-06 | 1.415764e-05 | 5.436924e-06 | 1.792029e-03 |\n",
       "| TCGA.CV.A460.01A | 0.7211691 | 0.150885458 | 2.310984e-03 | 1.378379e-07 | 3.647569e-02 | 3.290758e-02 | 7.177306e-03 | 4.907335e-02 | 4.230033e-07 |\n",
       "| TCGA.CV.7261.01A | 0.7686271 | 0.199999998 | 1.800759e-03 | 1.830788e-07 | 1.143315e-02 | 1.813197e-02 | 8.235639e-07 | 3.138454e-06 | 2.912679e-06 |\n",
       "| TCGA.CN.4736.01A | 0.5770123 | 0.202003425 | 3.214170e-07 | 1.087496e-01 | 8.823329e-02 | 1.477365e-02 | 1.064861e-03 | 1.154187e-06 | 8.161323e-03 |\n",
       "| TCGA.CR.7404.01A | 0.8335180 | 0.049152821 | 5.844858e-03 | 1.735372e-07 | 4.436907e-02 | 4.256713e-02 | 1.856149e-02 | 5.986233e-03 | 2.059526e-07 |\n",
       "| TCGA.UF.A719.01A | 0.9767740 | 0.009284403 | 1.501744e-05 | 6.696999e-07 | 5.670974e-03 | 7.098415e-03 | 1.145896e-03 | 2.142360e-06 | 8.476798e-06 |\n",
       "| TCGA.CV.7236.01A | 0.7583639 | 0.201827735 | 3.707119e-07 | 7.813978e-08 | 1.085050e-02 | 2.895305e-02 | 5.283327e-07 | 3.139558e-06 | 6.894808e-07 |\n",
       "| TCGA.CV.6951.01A | 0.9146561 | 0.059564714 | 4.368603e-07 | 2.203449e-02 | 1.716345e-03 | 1.806717e-03 | 3.409096e-06 | 5.381342e-07 | 2.172331e-04 |\n",
       "| TCGA.CN.4728.01A | 0.2860686 | 0.608054579 | 2.411349e-07 | 5.917761e-03 | 9.206015e-02 | 7.897528e-03 | 3.288993e-07 | 5.028132e-07 | 3.106541e-07 |\n",
       "| TCGA.CV.7090.01A | 0.7096929 | 0.227983815 | 1.494937e-07 | 1.164804e-07 | 5.363601e-02 | 8.685670e-03 | 5.132976e-07 | 3.897865e-07 | 4.457247e-07 |\n",
       "| TCGA.CV.5979.01A | 0.9170363 | 0.069411556 | 2.913286e-07 | 1.650445e-03 | 4.982065e-03 | 6.916896e-03 | 8.838452e-07 | 1.062019e-06 | 4.597641e-07 |\n",
       "| TCGA.CQ.7069.01A | 0.8867397 | 0.091163538 | 3.126233e-07 | 1.693463e-07 | 8.315407e-04 | 2.126299e-02 | 4.895251e-07 | 8.017098e-07 | 4.783386e-07 |\n",
       "| TCGA.CN.4733.01A | 0.4590225 | 0.313208243 | 2.204239e-02 | 1.200962e-02 | 1.121640e-01 | 5.323205e-02 | 2.709184e-02 | 4.165599e-04 | 8.127728e-04 |\n",
       "| TCGA.CR.7390.01A | 0.8226924 | 0.170653482 | 1.782093e-07 | 1.786800e-07 | 3.298995e-03 | 3.353692e-03 | 3.534756e-07 | 3.580305e-07 | 3.245375e-07 |\n",
       "| TCGA.CV.A45X.01A | 0.9860628 | 0.005683827 | 8.349780e-07 | 3.304159e-07 | 7.281100e-03 | 9.429661e-04 | 2.044738e-06 | 7.332573e-06 | 1.879439e-05 |\n",
       "| TCGA.IQ.A6SH.01A | 0.9423716 | 0.028385095 | 1.185881e-06 | 2.116455e-07 | 2.285112e-02 | 4.988359e-03 | 1.400820e-03 | 7.230511e-07 | 8.482273e-07 |\n",
       "| TCGA.CV.6962.11A | 0.9723949 | 0.018871943 | 1.635403e-04 | 3.305504e-07 | 3.465067e-03 | 4.592181e-03 | 5.021691e-04 | 1.727208e-06 | 8.165269e-06 |\n",
       "| TCGA.CV.6960.11A | 0.9791954 | 0.004831106 | 3.776268e-07 | 3.209457e-06 | 8.363308e-03 | 7.602948e-03 | 8.251732e-07 | 1.291781e-06 | 1.550674e-06 |\n",
       "| TCGA.CV.A464.01A | 0.6267057 | 0.311161624 | 3.606024e-07 | 4.331322e-02 | 9.255807e-03 | 9.559703e-03 | 2.505905e-06 | 6.786841e-07 | 4.215465e-07 |\n",
       "| TCGA.C9.A47Z.01A | 0.9654155 | 0.004341460 | 3.396085e-07 | 3.333502e-03 | 1.816612e-05 | 1.350464e-05 | 7.509604e-07 | 1.323662e-06 | 2.687544e-02 |\n",
       "| TCGA.CN.6010.01A | 0.8331282 | 0.090147619 | 1.197741e-02 | 2.411752e-04 | 9.119946e-03 | 5.437399e-02 | 1.010305e-03 | 1.018232e-06 | 3.096677e-07 |\n",
       "| TCGA.WA.A7GZ.11A | 0.5235703 | 0.003300802 | 1.269879e-07 | 4.731121e-01 | 3.789888e-07 | 1.547518e-05 | 2.477334e-07 | 2.683054e-07 | 3.049265e-07 |\n",
       "| TCGA.CV.7235.01A | 0.6329990 | 0.323112422 | 1.914870e-07 | 9.378561e-08 | 2.604538e-02 | 1.429738e-02 | 3.535064e-03 | 1.016330e-05 | 2.956404e-07 |\n",
       "| TCGA.CX.7086.01A | 0.9751108 | 0.006095150 | 2.551141e-04 | 6.397217e-07 | 8.412847e-03 | 9.428269e-03 | 6.740519e-04 | 2.040884e-05 | 2.704299e-06 |\n",
       "| TCGA.CV.6935.11A | 0.9811203 | 0.001239664 | 1.559001e-06 | 2.865151e-07 | 8.313372e-03 | 9.079049e-03 | 1.706022e-04 | 9.964355e-07 | 7.419330e-05 |\n",
       "| TCGA.P3.A6SW.01A | 0.8650169 | 0.055371537 | 1.725337e-02 | 2.161523e-07 | 3.544294e-02 | 1.423648e-02 | 1.130333e-02 | 1.372259e-03 | 2.950967e-06 |\n",
       "| TCGA.HD.A6HZ.01A | 0.7502374 | 0.116762381 | 8.185442e-03 | 3.767268e-02 | 5.054054e-02 | 2.933271e-02 | 4.331431e-03 | 2.936404e-03 | 1.003798e-06 |\n",
       "\n"
      ],
      "text/plain": [
       "                 tumor     Fibroblast   B cell       myocyte      Macrophage  \n",
       "TCGA.BB.4224.01A 0.8953963 3.295279e-03 1.535432e-07 2.076378e-03 2.663471e-06\n",
       "TCGA.H7.7774.01A 0.9807876 9.213523e-07 1.956431e-06 1.582816e-07 1.186069e-02\n",
       "TCGA.CV.6943.01A 0.5239461 3.799039e-01 1.548700e-03 2.208963e-07 7.545321e-02\n",
       "TCGA.CN.5374.01A 0.8727039 2.463040e-02 6.619988e-03 6.413547e-03 2.021994e-02\n",
       "TCGA.CQ.6227.01A 0.6538779 2.342006e-01 1.996756e-07 7.141557e-02 7.623701e-03\n",
       "TCGA.CV.6959.01A 0.7848157 9.008879e-02 3.630708e-05 6.450137e-02 2.570535e-02\n",
       "TCGA.F7.A61V.01A 0.9545372 1.147164e-02 1.391773e-03 2.241424e-02 4.397206e-03\n",
       "TCGA.CV.7413.01A 0.7576784 2.165254e-01 1.947499e-07 8.478491e-08 2.579297e-02\n",
       "TCGA.CV.7247.01A 0.7911627 1.108126e-01 1.374201e-07 7.858550e-02 6.057291e-07\n",
       "TCGA.CR.5249.01A 0.8287251 5.001096e-02 7.550117e-03 1.137713e-07 2.663733e-02\n",
       "TCGA.CQ.5331.01A 0.8679074 3.680547e-02 6.729025e-04 6.492139e-08 6.722354e-02\n",
       "TCGA.BB.8601.01A 0.9933812 4.261229e-03 7.357805e-05 2.507918e-07 3.730104e-06\n",
       "TCGA.CV.A45W.01A 0.7583385 9.038100e-02 4.573747e-02 2.842859e-07 5.930226e-02\n",
       "TCGA.CQ.7063.01A 0.8932472 2.143019e-02 2.929627e-07 2.839658e-07 6.462695e-02\n",
       "TCGA.CN.5373.01A 0.7648254 1.857341e-01 3.306371e-07 6.088100e-04 2.179955e-02\n",
       "TCGA.CV.A45T.01A 0.8189485 5.773553e-02 5.785000e-03 1.473200e-02 6.505784e-02\n",
       "TCGA.HD.A4C1.01A 0.9037093 8.132439e-02 7.313362e-07 1.059151e-07 4.587139e-03\n",
       "TCGA.CV.7438.11A 0.9736846 2.405088e-03 6.825740e-04 2.766721e-03 1.248155e-02\n",
       "TCGA.CV.5444.01A 0.4018990 5.008603e-01 1.421520e-07 3.634083e-02 5.472763e-02\n",
       "TCGA.BA.5556.01A 0.8490606 4.796692e-02 2.149780e-05 9.793571e-08 5.747951e-02\n",
       "TCGA.P3.A6SX.01A 0.8960362 9.110862e-02 1.878011e-07 1.098512e-02 6.988049e-07\n",
       "TCGA.CV.7242.11A 0.9755767 5.311162e-03 3.153993e-05 3.141680e-07 1.229840e-02\n",
       "TCGA.DQ.7592.01A 0.8323528 1.342008e-01 1.722611e-07 1.280968e-02 1.281682e-02\n",
       "TCGA.CV.6937.01A 0.8360634 1.441721e-01 3.585737e-07 4.275409e-07 1.778293e-02\n",
       "TCGA.QK.A8ZB.01A 0.8499897 1.257516e-01 6.130647e-03 1.031490e-07 6.951394e-03\n",
       "TCGA.CV.7432.01A 0.9688731 2.165490e-02 1.442955e-07 1.739435e-07 4.331192e-03\n",
       "TCGA.CV.7089.01A 0.9668070 8.355609e-03 2.990496e-07 1.403883e-07 8.618054e-03\n",
       "TCGA.CV.6939.11A 0.3108183 2.925750e-02 1.597606e-03 6.230553e-01 1.509185e-03\n",
       "TCGA.BA.4075.01A 0.9198085 4.745561e-02 3.472322e-07 2.176400e-03 2.556290e-02\n",
       "TCGA.T3.A92M.01A 0.6663292 2.896026e-01 1.676743e-03 1.417736e-07 3.400842e-02\n",
       "⋮                ⋮         ⋮            ⋮            ⋮            ⋮           \n",
       "TCGA.CV.7430.01A 0.9774183 0.015130849  3.765206e-07 1.369697e-07 6.725784e-04\n",
       "TCGA.D6.A74Q.01A 0.8842049 0.085482558  6.163754e-03 1.556808e-07 7.739195e-03\n",
       "TCGA.CV.7255.01A 0.9440443 0.027434705  2.563307e-07 9.352016e-03 1.086210e-06\n",
       "TCGA.CQ.6223.01A 0.9781348 0.006737177  3.301923e-04 1.067407e-07 1.298400e-02\n",
       "TCGA.CV.A460.01A 0.7211691 0.150885458  2.310984e-03 1.378379e-07 3.647569e-02\n",
       "TCGA.CV.7261.01A 0.7686271 0.199999998  1.800759e-03 1.830788e-07 1.143315e-02\n",
       "TCGA.CN.4736.01A 0.5770123 0.202003425  3.214170e-07 1.087496e-01 8.823329e-02\n",
       "TCGA.CR.7404.01A 0.8335180 0.049152821  5.844858e-03 1.735372e-07 4.436907e-02\n",
       "TCGA.UF.A719.01A 0.9767740 0.009284403  1.501744e-05 6.696999e-07 5.670974e-03\n",
       "TCGA.CV.7236.01A 0.7583639 0.201827735  3.707119e-07 7.813978e-08 1.085050e-02\n",
       "TCGA.CV.6951.01A 0.9146561 0.059564714  4.368603e-07 2.203449e-02 1.716345e-03\n",
       "TCGA.CN.4728.01A 0.2860686 0.608054579  2.411349e-07 5.917761e-03 9.206015e-02\n",
       "TCGA.CV.7090.01A 0.7096929 0.227983815  1.494937e-07 1.164804e-07 5.363601e-02\n",
       "TCGA.CV.5979.01A 0.9170363 0.069411556  2.913286e-07 1.650445e-03 4.982065e-03\n",
       "TCGA.CQ.7069.01A 0.8867397 0.091163538  3.126233e-07 1.693463e-07 8.315407e-04\n",
       "TCGA.CN.4733.01A 0.4590225 0.313208243  2.204239e-02 1.200962e-02 1.121640e-01\n",
       "TCGA.CR.7390.01A 0.8226924 0.170653482  1.782093e-07 1.786800e-07 3.298995e-03\n",
       "TCGA.CV.A45X.01A 0.9860628 0.005683827  8.349780e-07 3.304159e-07 7.281100e-03\n",
       "TCGA.IQ.A6SH.01A 0.9423716 0.028385095  1.185881e-06 2.116455e-07 2.285112e-02\n",
       "TCGA.CV.6962.11A 0.9723949 0.018871943  1.635403e-04 3.305504e-07 3.465067e-03\n",
       "TCGA.CV.6960.11A 0.9791954 0.004831106  3.776268e-07 3.209457e-06 8.363308e-03\n",
       "TCGA.CV.A464.01A 0.6267057 0.311161624  3.606024e-07 4.331322e-02 9.255807e-03\n",
       "TCGA.C9.A47Z.01A 0.9654155 0.004341460  3.396085e-07 3.333502e-03 1.816612e-05\n",
       "TCGA.CN.6010.01A 0.8331282 0.090147619  1.197741e-02 2.411752e-04 9.119946e-03\n",
       "TCGA.WA.A7GZ.11A 0.5235703 0.003300802  1.269879e-07 4.731121e-01 3.789888e-07\n",
       "TCGA.CV.7235.01A 0.6329990 0.323112422  1.914870e-07 9.378561e-08 2.604538e-02\n",
       "TCGA.CX.7086.01A 0.9751108 0.006095150  2.551141e-04 6.397217e-07 8.412847e-03\n",
       "TCGA.CV.6935.11A 0.9811203 0.001239664  1.559001e-06 2.865151e-07 8.313372e-03\n",
       "TCGA.P3.A6SW.01A 0.8650169 0.055371537  1.725337e-02 2.161523e-07 3.544294e-02\n",
       "TCGA.HD.A6HZ.01A 0.7502374 0.116762381  8.185442e-03 3.767268e-02 5.054054e-02\n",
       "                 Endothelial  T cell       Dendritic    Mast        \n",
       "TCGA.BB.4224.01A 1.099243e-06 2.711799e-07 4.547351e-07 9.922738e-02\n",
       "TCGA.H7.7774.01A 7.062818e-07 1.267113e-04 1.133469e-06 7.220150e-03\n",
       "TCGA.CV.6943.01A 8.543457e-03 1.060355e-02 3.213430e-07 5.962804e-07\n",
       "TCGA.CN.5374.01A 2.152436e-02 2.999286e-02 1.789418e-02 8.044354e-07\n",
       "TCGA.CQ.6227.01A 3.287952e-02 3.276224e-07 4.224889e-07 1.701781e-06\n",
       "TCGA.CV.6959.01A 3.484607e-02 6.940279e-07 4.514340e-06 1.185480e-06\n",
       "TCGA.F7.A61V.01A 5.219229e-03 5.633430e-04 4.516596e-06 8.426878e-07\n",
       "TCGA.CV.7413.01A 4.341206e-07 1.038621e-06 2.309817e-07 1.216114e-06\n",
       "TCGA.CV.7247.01A 1.943738e-02 1.658183e-07 6.054190e-07 2.752071e-07\n",
       "TCGA.CR.5249.01A 3.129438e-02 3.085065e-02 2.493104e-02 3.331009e-07\n",
       "TCGA.CQ.5331.01A 2.205727e-02 5.329257e-03 3.620704e-06 4.945356e-07\n",
       "TCGA.BB.8601.01A 2.237834e-03 1.768300e-06 2.015228e-06 3.842106e-05\n",
       "TCGA.CV.A45W.01A 3.803786e-02 5.694007e-03 2.508070e-03 5.767332e-07\n",
       "TCGA.CQ.7063.01A 1.244862e-02 6.942133e-03 4.127833e-05 1.263061e-03\n",
       "TCGA.CN.5373.01A 4.760714e-06 7.257815e-07 8.311730e-07 2.702557e-02\n",
       "TCGA.CV.A45T.01A 1.423510e-02 1.939667e-02 9.113431e-05 4.018240e-03\n",
       "TCGA.HD.A4C1.01A 1.037395e-02 1.168693e-06 1.853892e-06 1.389217e-06\n",
       "TCGA.CV.7438.11A 1.094154e-03 6.450133e-03 1.981943e-04 2.369504e-04\n",
       "TCGA.CV.5444.01A 6.170893e-03 4.490983e-07 4.175766e-07 2.911519e-07\n",
       "TCGA.BA.5556.01A 2.534477e-02 1.919881e-02 9.241382e-04 3.625550e-06\n",
       "TCGA.P3.A6SX.01A 1.867874e-03 4.670143e-07 3.429470e-07 5.174869e-07\n",
       "TCGA.CV.7242.11A 4.594129e-03 2.158675e-03 2.730977e-05 1.801851e-06\n",
       "TCGA.DQ.7592.01A 5.765994e-03 9.210478e-04 8.855847e-07 1.131870e-03\n",
       "TCGA.CV.6937.01A 1.976317e-03 7.544563e-07 3.166395e-06 5.797741e-07\n",
       "TCGA.QK.A8ZB.01A 7.469520e-03 5.701797e-07 1.859023e-06 3.704592e-03\n",
       "TCGA.CV.7432.01A 5.137664e-03 3.056553e-07 1.084470e-06 1.401741e-06\n",
       "TCGA.CV.7089.01A 1.516107e-02 1.011682e-03 6.487607e-06 3.969543e-05\n",
       "TCGA.CV.6939.11A 3.375961e-02 2.043617e-06 2.373454e-07 1.717001e-07\n",
       "TCGA.BA.4075.01A 4.994196e-03 7.253185e-07 9.011630e-07 4.677923e-07\n",
       "TCGA.T3.A92M.01A 3.612272e-03 4.743024e-03 2.724614e-05 3.395150e-07\n",
       "⋮                ⋮            ⋮            ⋮            ⋮           \n",
       "TCGA.CV.7430.01A 6.533762e-03 1.229668e-06 1.957884e-06 2.408299e-04\n",
       "TCGA.D6.A74Q.01A 9.906454e-03 6.216704e-03 9.684231e-05 1.894224e-04\n",
       "TCGA.CV.7255.01A 1.916546e-02 5.195208e-07 4.008375e-07 1.231915e-06\n",
       "TCGA.CQ.6223.01A 2.129298e-06 1.415764e-05 5.436924e-06 1.792029e-03\n",
       "TCGA.CV.A460.01A 3.290758e-02 7.177306e-03 4.907335e-02 4.230033e-07\n",
       "TCGA.CV.7261.01A 1.813197e-02 8.235639e-07 3.138454e-06 2.912679e-06\n",
       "TCGA.CN.4736.01A 1.477365e-02 1.064861e-03 1.154187e-06 8.161323e-03\n",
       "TCGA.CR.7404.01A 4.256713e-02 1.856149e-02 5.986233e-03 2.059526e-07\n",
       "TCGA.UF.A719.01A 7.098415e-03 1.145896e-03 2.142360e-06 8.476798e-06\n",
       "TCGA.CV.7236.01A 2.895305e-02 5.283327e-07 3.139558e-06 6.894808e-07\n",
       "TCGA.CV.6951.01A 1.806717e-03 3.409096e-06 5.381342e-07 2.172331e-04\n",
       "TCGA.CN.4728.01A 7.897528e-03 3.288993e-07 5.028132e-07 3.106541e-07\n",
       "TCGA.CV.7090.01A 8.685670e-03 5.132976e-07 3.897865e-07 4.457247e-07\n",
       "TCGA.CV.5979.01A 6.916896e-03 8.838452e-07 1.062019e-06 4.597641e-07\n",
       "TCGA.CQ.7069.01A 2.126299e-02 4.895251e-07 8.017098e-07 4.783386e-07\n",
       "TCGA.CN.4733.01A 5.323205e-02 2.709184e-02 4.165599e-04 8.127728e-04\n",
       "TCGA.CR.7390.01A 3.353692e-03 3.534756e-07 3.580305e-07 3.245375e-07\n",
       "TCGA.CV.A45X.01A 9.429661e-04 2.044738e-06 7.332573e-06 1.879439e-05\n",
       "TCGA.IQ.A6SH.01A 4.988359e-03 1.400820e-03 7.230511e-07 8.482273e-07\n",
       "TCGA.CV.6962.11A 4.592181e-03 5.021691e-04 1.727208e-06 8.165269e-06\n",
       "TCGA.CV.6960.11A 7.602948e-03 8.251732e-07 1.291781e-06 1.550674e-06\n",
       "TCGA.CV.A464.01A 9.559703e-03 2.505905e-06 6.786841e-07 4.215465e-07\n",
       "TCGA.C9.A47Z.01A 1.350464e-05 7.509604e-07 1.323662e-06 2.687544e-02\n",
       "TCGA.CN.6010.01A 5.437399e-02 1.010305e-03 1.018232e-06 3.096677e-07\n",
       "TCGA.WA.A7GZ.11A 1.547518e-05 2.477334e-07 2.683054e-07 3.049265e-07\n",
       "TCGA.CV.7235.01A 1.429738e-02 3.535064e-03 1.016330e-05 2.956404e-07\n",
       "TCGA.CX.7086.01A 9.428269e-03 6.740519e-04 2.040884e-05 2.704299e-06\n",
       "TCGA.CV.6935.11A 9.079049e-03 1.706022e-04 9.964355e-07 7.419330e-05\n",
       "TCGA.P3.A6SW.01A 1.423648e-02 1.130333e-02 1.372259e-03 2.950967e-06\n",
       "TCGA.HD.A6HZ.01A 2.933271e-02 4.331431e-03 2.936404e-03 1.003798e-06"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "res1$res$final.gibbs.thet"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "id": "be7f69b7",
   "metadata": {},
   "outputs": [],
   "source": []
  }
 ],
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  "kernelspec": {
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   "language": "R",
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   "mimetype": "text/x-r-source",
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