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@mpmeers mpmeers released this 05 Nov 00:52
· 10 commits to master since this release
SEACRv1.2
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Learn about vigilant mode.

SEACR v1.2 contains the following changes:

  • Fixed a bug in lines 166 and 168 in which misplaced brackets caused the misreporting of the max signal region terminal coordinate for merged signal blocks
  • Added a counter to keep track of the number of component bedgraph lines that compose each signal block, and a function to calculate the minimum threshold of lines per signal block at which there is a smaller percentage of target signal blocks remaining than control. This is meant to be used as a filter for signal blocks that pass the total signal threshold despite being composed of very few bedgraph lines, which are unlikely to be true peaks.
  • Changed how the dataframe for density plotting is truncated (previously a hard-coded 90% cutoff): a dataframe of list quantile (i.e. line #/max line#) vs. value quantile (i.e. value/max value) is derived, and the threshold is selected by finding the dataframe pair for which the orthogonal distance below the line defined by (0,0);(1,1) is maximized.
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