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SEACR v1.1
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@mpmeers mpmeers released this 30 Oct 21:40
· 22 commits to master since this release
v1.1
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Learn about vigilant mode.

SEACR v1.1 contains the following changes:

  • Changed "union" and "AUC" modes to "relaxed" and "stringent" modes, respectively.
  • Removed maximum signal threshold from "relaxed" mode and replaced it with an alternate total signal threshold that uses the point halfway between the knee and the peak of the total signal curve as described in the manuscript text. This change improves performance at high read depth.
  • Implemented alternate threshold test that searches for any thresholds that come within 95% of the optimal threshold. This change avoids spurious thresholds that are overselective in some datasets.
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