diff --git a/Library/Homebrew/extend/ENV/super.rb b/Library/Homebrew/extend/ENV/super.rb
index 89f7ecfa5e654..c21bd3ce846f2 100644
--- a/Library/Homebrew/extend/ENV/super.rb
+++ b/Library/Homebrew/extend/ENV/super.rb
@@ -93,6 +93,11 @@ def setup_build_environment(formula: nil, cc: nil, build_bottle: false, bottle_a
     # Prevent Go from automatically downloading a newer toolchain than the one that we have.
     # https://tip.golang.org/doc/toolchain
     self["GOTOOLCHAIN"] = "local"
+    # Prevent Python packages from using bundled libraries by default.
+    # Currently for hidapi, pyzmq and pynacl
+    self["HIDAPI_SYSTEM_HIDAPI"] = "1"
+    self["PYZMQ_NO_BUNDLE"] = "1"
+    self["SODIUM_INSTALL"] = "system"
 
     set_debug_symbols if debug_symbols