ISARIC VERTEX is a web-based application designed for local use by users. It serves as an analysis tool for data captured through our complementary tools: ISARIC ARC and ISARIC BRIDGE.
VERTEX is a web-based application designed to present graphs and tables based on key relevant research questions that need to be quickly answered during an outbreak. Currently, VERTEX performs descriptive analysis, which can identify the spectrum of clinical features in a disease outbreak. New research questions will be added by the ISARIC team and the wider scientific community, enabling the creation and sharing of additional analysis methods.
ISARIC VERTEX enables users to connect with a REDCap database through an API call. For detailed instructions, please refer to our Getting Started with VERTEX guide.
VERTEX has three main elements:
- Main App: A map that visually represents the number and country of patients in the REDCap database.
- Menu: A menu containing a series of buttons that open different insight panels.
- Insight Panels: Sets of visuals, each related to specific research questions.
VERTEX processes and visualizes data using the concept of Reproducible Analytical Pipelines (RAPs). RAPs are a set of resuable functions or blocks of code that can request specific variables from an ISARIC ARC-formatted REDCap database. These functions then process the data to generate dataframes, which can then be visualized interactively through a Plotly Dash app.
VERTEX Version 1.0 includes insight panels developed for the following research questions:
- Clinical characterization of on presentation, including:
- demographics and comorbidities
- pregnancy
- transmission or exposure
- signs, symptoms, labs and vitals from the first 24hr after admission
- Patient outcomes, including complications
Additionally, if you want to create your own insight panel, please follow our Creating an Insight Panel guide.
To get started with VERTEX, please refer to our Getting Started with VERTEX guide.
If you encounter any issues or have suggestions for improvements, we encourage you to submit an issue on this repository or reach out to us via email at data@isaric.org.
- Esteban Garcia-Gallo - esteban.garcia@ndm.ox.ac.uk
- Tom Edinburgh - tom.edinburgh@ndm.ox.ac.uk
- Leonardo Bastos - lslbastos@puc-rio.br
- Igor Peres - igor.peres@puc-rio.br
- Luiz Eduardo Raffaini lemraffaini@gmail.com
- Sara Duque-Vallejo - sara.duquevallejo@ndm.ox.ac.uk
- Laura Merson - laura.merson@ndm.ox.ac.uk
- Elise Pesonel - elise.pesonel@ndm.ox.ac.uk
Note: VERTEX is maintained by ISARIC. For inquiries, support, or collaboration, please contact us.