diff --git a/requirements.txt b/requirements.txt
index 575ac3c2..23e24e0c 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -1,5 +1,4 @@
 anndata==0.9.1
-biopython==1.83
 click==8.0.1
 combat==0.3.3
 data_cache>=0.1.6