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<html><head>
<script language="JavaScript" type="text/javascript" src="index_files/calc.js"></script>
<meta name="Author" content="Victor Matveev">
<meta name="description" content="Victor Matveev publication simulation files">
<meta name="Keywords" content="Simulation files for the J Neurosci article on Ca2+ current vs channel cooperativity of exocytosis">
<meta http-equiv="Content-Type" content="text/html; charset=ISO-8859-1">
<title>Code for manuscript "Ca<sup>2+</sup> current vs.
Ca<sup>2+</sup> channel cooperativity of exocytosis" (2009)
Matveev Bertram Sherman</title>
<link rel="STYLESHEET" type="text/css" href="index_files/victor.css">
<style type="text/css">
A.SCRIPT:link {font-family:sans-serif; text-decoration:none; font-size:8pt; font-style:bold; color:red; }
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CODE {font-size:8pt; color:#550055;}
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</style>
<!-- base href="http://web.njit.edu/~matveev/Scripts/MvsN/" -->
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B O D Y
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<script language="JavaScript" type="text/javascript">
makeTitle("Model Code: Ca<sup>2+</sup> current vs. Ca<sup>2+</sup> channel cooperativity");
</script><table width="620"><tbody><tr><td class="title" colspan="5" height="33" width="100%">Model Code: Ca<sup>2+</sup> current vs. Ca<sup>2+</sup> channel cooperativity</td></tr><tr><td class="TCALC"><a class="TMENU" href="http://web.njit.edu/%7Ematveev/calc.html" target="_self">CalC Download</a></td> <td class="TCALC"><a class="TMENU" href="http://web.njit.edu/%7Ematveev/calc/manual.html" target="_self">CalC Manual</a></td> <td class="TCALC"><a class="TMENU" href="http://web.njit.edu/%7Ematveev/calc/scripts.html" target="_self">CalC Scripts</a></td> <td class="TCALC"><a class="TMENU" href="http://web.njit.edu/%7Ematveev/calc/calc_pub.html" target="_self">CalC Publications</a></td> <td class="TMENU"><a class="TMENU" href="http://web.njit.edu/%7Ematveev/" target="_top">Victor's Homepage</a></td> </tr></tbody></table><br>
<br>
<!-- br><br>
<hr>
<br -->
<!-- ===============================================================================
MAIN TABLE
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<table width="600" cellpadding="2">
<tbody><tr><td valign="top">
</td><td>
The scripts following below reproduce the simulation results presented in the manuscript:
<br><br>
<table border="1" cellpadding="3"><tbody><tr><td class="COLOR" align="center">
Victor V. Matveev, Richard Bertram and Arthur Sherman (2009)<br>
<b>Ca<sup>2+</sup> current vs. Ca<sup>2+</sup> channel cooperativity of exocytosis</b><br>
Journal of Neuroscience, <b>29</b>(39): 12196-12209.
<a href="http://www.jneurosci.org/cgi/content/abstract/29/39/12196" target="_top">[ Abstract ]</a>
<a href="http://www.jneurosci.org/cgi/content/full/29/39/12196" target="_top">[ Full Text ]</a>
</td></tr></tbody></table>
<br>
<br>
</td></tr>
<tr><td valign="top">
<font color="red">♦</font> <a href="http://web.njit.edu/%7Ematveev/Scripts/MvsN/Fig1.par" class="SCRIPT">Fig1.par</a>
</td><td>
This CalC script generates the first figure of the manuscript. It requires a single command-line parameters, the
total buffer concentration (in μM) (e.g. run <code>calc Fig1.par 100</code>). The simulation
produces an ASCII data file with five columns:
(1) single-channel Ca<sip>2+ current (varied from 0.001 to 1 pA);
(2) maximal release produced by a 1ms-long
current pulse;
(3) corresponding maximal [Ca<sip>2+] at release site, 30 nm from channel;
(4) maximal volume-averaged [Ca<sip>2+];
(5) time to peak release after simulation start.
<br><br>
</sip></sip></sip></td></tr>
<tr><td valign="top">
<font color="red">♦</font> <a href="http://web.njit.edu/%7Ematveev/Scripts/MvsN/Fig1.m" class="SCRIPT">Fig1.m</a>
</td><td>
A MATLAB m-file that generates Figure 1 using data produced by CalC script <code>Fig1.par</code> above.
<br><br>
</td></tr>
<tr><td valign="top">
<font color="red">♦</font> <a href="http://web.njit.edu/%7Ematveev/Scripts/MvsN/Fig7_8.par" class="SCRIPT">Fig7_8.par</a>
</td><td>
This CalC script generates data for Figures 7 and 8 of the manuscript. The simulation
produces an ASCII data file used by MATLAB script <code>Fig7_8.m</code> below.
<br><br>
</td></tr>
<tr><td valign="top">
<font color="red">♦</font> <a href="http://web.njit.edu/%7Ematveev/Scripts/MvsN/Fig7_8.m" class="SCRIPT">Fig7_8.m</a>
</td><td>
A MATLAB m-file that generates Figures 7 and 8 using data produced by CalC script <code>Fig7_8.par</code> above.
<br><br>
</td></tr>
<tr><td valign="top">
<font color="red">♦</font> <a href="http://web.njit.edu/%7Ematveev/Scripts/MvsN/process2D.m" class="SCRIPT">process2D.m</a>
</td><td>
A simple MATLAB data parsing script required by MATLAB m-files and <code>Fig1.m</code> and <code>Fig7_8.m</code>.
<br><br>
</td></tr>
</tbody></table>
<hr>
<br>
Supported in part by the <b>National Science Foundation</b> grant
<b>DMS 0817703</b> to Victor Matveev
<br><br>
<!-- =============================================================================== -->
<!-- =============================================================================== -->
<address>
<small>
<a href="http://web.njit.edu/%7Ematveev" target="_top">Victor Matveev</a>
</small>
</address>
<small>
This server is running a
<a href="http://www.redhat.com/" target="_top">Redhat</a> distribution of
<a href="http://www.linux.org/" target="_top">Linux</a>.
<br>
<!-- Created: Sun Apr 12 18:25:17 EDT 1998 -->
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Last modified: January 8, 2010
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</small>
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