GitHub - ModelDBRepository/7509: CA1 pyramidal neuron: Synaptic Scaling (Magee, Cook 2000)

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CA1 pyramidal neuron: Synaptic Scaling (Magee, Cook 2000)

modeldb.science/7509

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Name		Name	Last commit message	Last commit date
Latest commit History 1 Commit
ca1.nrn		ca1.nrn
main.hoc		main.hoc
main_example_epsps.hoc		main_example_epsps.hoc
mosinit.hoc		mosinit.hoc
readme.txt		readme.txt
shape_plot.ses		shape_plot.ses

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This collection of model files is associated with the paper:

Magee JC, Cook EP. Somatic EPSP amplitude is independent of synapse 
location in hippocampal pyramidal neurons. Nat Neurosci. 2000 Sep;3(9):895-903.

When auto-launched from ModelDB the program recreates fig4 a, b, c.

For more information about the model email Jeffrey Magee: jmagee@lsumc.edu
This model had minor modifications by Michael Hines and Tom Morse.

How to run the model (assuming that Neuron 5.2 or greater is installed)

PC platform:

	Download the zip file and extract its contents.
	Double click-on mosinit.hoc in Windows Explorer.

Unix platform:

	Download the zip file and extract its contents.
	cd to the directory that zip file created and type
	nrngui mosinit.hoc

MAC platform:

	Download the zip file.
	Drag and drop the zip file onto the mos2nrn icon.