diff --git a/pkgs/development/compilers/llvm/16/llvm/default.nix b/pkgs/development/compilers/llvm/16/llvm/default.nix
index 60e864d6a132d..4ae1178a4bab3 100644
--- a/pkgs/development/compilers/llvm/16/llvm/default.nix
+++ b/pkgs/development/compilers/llvm/16/llvm/default.nix
@@ -220,6 +220,11 @@ in
       --replace "PassBuilderCallbacksTest.cpp" ""
     rm unittests/IR/PassBuilderCallbacksTest.cpp
     rm test/tools/llvm-objcopy/ELF/mirror-permissions-unix.test
+
+    # Fails in the presence of anti-virus software or other intrusion-detection software that
+    # modifies the atime when run. See #284056.
+    rm test/tools/llvm-objcopy/ELF/strip-preserve-atime.test
+
     # timing-based tests are trouble
     rm utils/lit/tests/googletest-timeout.py
   '' + optionalString stdenv.hostPlatform.isMusl ''
diff --git a/pkgs/development/compilers/llvm/17/llvm/default.nix b/pkgs/development/compilers/llvm/17/llvm/default.nix
index 636c2d2ca9352..a8e3c03f8934d 100644
--- a/pkgs/development/compilers/llvm/17/llvm/default.nix
+++ b/pkgs/development/compilers/llvm/17/llvm/default.nix
@@ -219,6 +219,10 @@ stdenv.mkDerivation (rec {
       --replace "PassBuilderCallbacksTest.cpp" ""
     rm unittests/IR/PassBuilderCallbacksTest.cpp
     rm test/tools/llvm-objcopy/ELF/mirror-permissions-unix.test
+
+    # Fails in the presence of anti-virus software or other intrusion-detection software that
+    # modifies the atime when run. See #284056.
+    rm test/tools/llvm-objcopy/ELF/strip-preserve-atime.test
   '' + optionalString stdenv.hostPlatform.isMusl ''
     patch -p1 -i ${../../common/llvm/TLI-musl.patch}
     substituteInPlace unittests/Support/CMakeLists.txt \
diff --git a/pkgs/development/compilers/llvm/git/llvm/default.nix b/pkgs/development/compilers/llvm/git/llvm/default.nix
index c1679a2e6ba8b..e187f1a9ac539 100644
--- a/pkgs/development/compilers/llvm/git/llvm/default.nix
+++ b/pkgs/development/compilers/llvm/git/llvm/default.nix
@@ -219,6 +219,10 @@ stdenv.mkDerivation (rec {
       --replace "PassBuilderCallbacksTest.cpp" ""
     rm unittests/IR/PassBuilderCallbacksTest.cpp
     rm test/tools/llvm-objcopy/ELF/mirror-permissions-unix.test
+
+    # Fails in the presence of anti-virus software or other intrusion-detection software that
+    # modifies the atime when run. See #284056.
+    rm test/tools/llvm-objcopy/ELF/strip-preserve-atime.test
   '' + optionalString stdenv.hostPlatform.isMusl ''
     patch -p1 -i ${../../common/llvm/TLI-musl.patch}
     substituteInPlace unittests/Support/CMakeLists.txt \