diff --git a/Qualification/Input/Content/Qualification_DDI_CYP3A4_network_description.md b/Qualification/Input/Content/Qualification_DDI_CYP3A4_network_description.md index 9003926..3e1b9e4 100644 --- a/Qualification/Input/Content/Qualification_DDI_CYP3A4_network_description.md +++ b/Qualification/Input/Content/Qualification_DDI_CYP3A4_network_description.md @@ -5,19 +5,19 @@ The following perpetrator compounds were selected: - **Rifampicin** (strong CYP3A4 inducer) Model snapshot and evaluation plan (*release* **v1.2**): https://github.com/Open-Systems-Pharmacology/Rifampicin-Model/releases/tag/v1.2 - **Carbamazepine** (moderate CYP3A4 inducer) - Model snapshot and evaluation plan (*release* **v1.2**): [Release Model snapshot and evaluation plan version 1.2 · Open-Systems-Pharmacology/Carbamazepine-Model · GitHub](https://github.com/Open-Systems-Pharmacology/Carbamazepine-Model/releases/tag/v1.2) + Model snapshot and evaluation plan (*release* **v1.3**): [https://github.com/Open-Systems-Pharmacology/Carbamazepine-Model/releases/tag/v1.3](https://github.com/Open-Systems-Pharmacology/Carbamazepine-Model/releases/tag/v1.3) - **Efavirenz** (moderate CYP3A4 inducer) Model snapshot and evaluation plan (*release* **v1.1**): https://github.com/Open-Systems-Pharmacology/Efavirenz-Model/releases/tag/v1.1 - **Cimetidine** (weak CYP3A4 inhibitor) - Model snapshot and evaluation plan (*release* **v1.1**): https://github.com/Open-Systems-Pharmacology/Cimetidine-Model/releases/tag/v1.1 + Model snapshot and evaluation plan (*release* **v1.2**): https://github.com/Open-Systems-Pharmacology/Cimetidine-Model/releases/tag/v1.2 - **Fluvoxamine** (weak/moderate CYP3A4 inhibitor) - Model snapshot and evaluation plan (*release* **v1.1**): https://github.com/Open-Systems-Pharmacology/Fluvoxamine-Model/releases/tag/v1.1 + Model snapshot and evaluation plan (*release* **v1.2**): https://github.com/Open-Systems-Pharmacology/Fluvoxamine-Model/releases/tag/v1.2 - **Verapamil** (moderate CYP3A4 inhibitor) Model snapshot and evaluation plan (*release* **v1.2**): https://github.com/Open-Systems-Pharmacology/Verapamil-Model/releases/tag/v1.2 - **Fluconazole** (moderate CYP3A4 inhibitor) Model snapshot and evaluation plan (*release* **v1.0**): https://github.com/Open-Systems-Pharmacology/Fluconazole-Model/releases/tag/v1.0 - **Erythromycin** (moderate CYP3A4 inhibitor) - Model snapshot and evaluation plan (*release* **v1.2**): https://github.com/Open-Systems-Pharmacology/Erythromycin-Model/releases/tag/v1.2 + Model snapshot and evaluation plan (*release* **v1.3**): https://github.com/Open-Systems-Pharmacology/Erythromycin-Model/releases/tag/v1.3 - **Clarithromycin** (strong CYP3A4 inhibitor) Model snapshot and evaluation plan (*release* **v1.2**): https://github.com/Open-Systems-Pharmacology/Clarithromycin-Model/releases/tag/v1.2 - **Itraconazole** including metabolites (strong CYP3A4 inhibitor)