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updated with cimetidine release version v1.2 #29

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Jan 11, 2024
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2 changes: 1 addition & 1 deletion Qualification/Input/Content/Cimetidine-Alfentanil-DDI.md
Original file line number Diff line number Diff line change
@@ -1,5 +1,5 @@
The release of the snapshot containing the respective simulations can be found here:
https://github.com/Open-Systems-Pharmacology/Cimetidine-Alfentanil-DDI/releases/tag/v1.1.
https://github.com/Open-Systems-Pharmacology/Cimetidine-Alfentanil-DDI/releases/tag/v1.2.

The cimetidine-alfentanil interaction was evaluated using a single clinical DDI study quantifying the interaction following two different dosing regimens ([Kienlen 1993](#4-references)).

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2 changes: 1 addition & 1 deletion Qualification/Input/Content/Cimetidine-Alprazolam-DDI.md
Original file line number Diff line number Diff line change
@@ -1,5 +1,5 @@
The release of the snapshot containing the respective simulations can be found here:
https://github.com/Open-Systems-Pharmacology/Cimetidine-Alprazolam-DDI/releases/tag/v1.1.
https://github.com/Open-Systems-Pharmacology/Cimetidine-Alprazolam-DDI/releases/tag/v1.2.

The cimetidine-alprazolam interaction was evaluated using two clinical DDI studies quantifying the interaction following two different dosing regimens ([Pourbaix 1985](#4-references), [Abernethy 1983](#4-references)).

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2 changes: 1 addition & 1 deletion Qualification/Input/Content/Cimetidine-Midazolam-DDI.md
Original file line number Diff line number Diff line change
@@ -1,5 +1,5 @@
The release of the snapshot containing the respective simulations can be found here:
https://github.com/Open-Systems-Pharmacology/Cimetidine-Midazolam-DDI/releases/tag/v1.1.
https://github.com/Open-Systems-Pharmacology/Cimetidine-Midazolam-DDI/releases/tag/v1.2.

The cimetidine-midazolam interaction was evaluated using five clinical DDI studies quantifying the interaction following six different dosing regimens ([Elliott 1984](#4-references), [Fee 1987](#4-references), [Greenblatt 1986](#4-references), [Martinez 1999](#4-references), [Salonen 1986](#4-references)).

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2 changes: 1 addition & 1 deletion Qualification/Input/Content/Cimetidine-Triazolam-DDI.md
Original file line number Diff line number Diff line change
@@ -1,5 +1,5 @@
The release of the snapshot containing the respective simulations can be found here:
https://github.com/Open-Systems-Pharmacology/Cimetidine-Triazolam-DDI/releases/tag/v1.1.
https://github.com/Open-Systems-Pharmacology/Cimetidine-Triazolam-DDI/releases/tag/v1.2.

The cimetidine-triazolam interaction was evaluated using four clinical DDI studies quantifying the interaction following four different dosing regimens ([Pourbaix 1985](#4-references), [Abernethy 1983](#4-references), [Cox 1986](#4-references), [Friedman 1988](#4-references)).

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2 changes: 1 addition & 1 deletion Qualification/Input/Content/Cimetidine-Verapamil-DDI.md
Original file line number Diff line number Diff line change
@@ -1,5 +1,5 @@
The release of the snapshot containing the respective simulations can be found here:
https://github.com/Open-Systems-Pharmacology/Cimetidine-Verapamil-DDI/releases/tag/v1.1.
https://github.com/Open-Systems-Pharmacology/Cimetidine-Verapamil-DDI/releases/tag/v1.2.

The cimetidine-verapamil interaction was evaluated using a single clinical DDI study quantifying the interaction following two different dosing regimens ([Smith 1984](#4-references)).

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12 changes: 6 additions & 6 deletions Qualification/Input/qualification_plan.json
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Expand Up @@ -11,7 +11,7 @@
},
{
"Id": "Cimetidine",
"Path": "https://raw.githubusercontent.com/Open-Systems-Pharmacology/Cimetidine-Model/v1.1/Cimetidine-Model.json"
"Path": "https://raw.githubusercontent.com/Open-Systems-Pharmacology/Cimetidine-Model/v1.2/Cimetidine-Model.json"
},
{
"Id": "Clarithromycin",
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},
{
"Id": "Cimetidine-Alfentanil-DDI",
"Path": "https://raw.githubusercontent.com/Open-Systems-Pharmacology/Cimetidine-Alfentanil-DDI/v1.1/Cimetidine-Alfentanil-DDI.json",
"Path": "https://raw.githubusercontent.com/Open-Systems-Pharmacology/Cimetidine-Alfentanil-DDI/v1.2/Cimetidine-Alfentanil-DDI.json",
"BuildingBlocks": [
{
"Type": "Compound",
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},
{
"Id": "Cimetidine-Alprazolam-DDI",
"Path": "https://raw.githubusercontent.com/Open-Systems-Pharmacology/Cimetidine-Alprazolam-DDI/v1.1/Cimetidine-Alprazolam-DDI.json",
"Path": "https://raw.githubusercontent.com/Open-Systems-Pharmacology/Cimetidine-Alprazolam-DDI/v1.2/Cimetidine-Alprazolam-DDI.json",
"BuildingBlocks": [
{
"Type": "Compound",
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},
{
"Id": "Cimetidine-Midazolam-DDI",
"Path": "https://raw.githubusercontent.com/Open-Systems-Pharmacology/Cimetidine-Midazolam-DDI/v1.1/Cimetidine-Midazolam-DDI.json",
"Path": "https://raw.githubusercontent.com/Open-Systems-Pharmacology/Cimetidine-Midazolam-DDI/v1.2/Cimetidine-Midazolam-DDI.json",
"BuildingBlocks": [
{
"Type": "Compound",
Expand Down Expand Up @@ -987,7 +987,7 @@
},
{
"Id": "Cimetidine-Triazolam-DDI",
"Path": "https://raw.githubusercontent.com/Open-Systems-Pharmacology/Cimetidine-Triazolam-DDI/v1.1/Cimetidine-Triazolam-DDI.json",
"Path": "https://raw.githubusercontent.com/Open-Systems-Pharmacology/Cimetidine-Triazolam-DDI/v1.2/Cimetidine-Triazolam-DDI.json",
"BuildingBlocks": [
{
"Type": "Compound",
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},
{
"Id": "Cimetidine-Verapamil-DDI",
"Path": "https://raw.githubusercontent.com/Open-Systems-Pharmacology/Cimetidine-Verapamil-DDI/v1.1/Cimetidine-Verapamil-DDI.json",
"Path": "https://raw.githubusercontent.com/Open-Systems-Pharmacology/Cimetidine-Verapamil-DDI/v1.2/Cimetidine-Verapamil-DDI.json",
"BuildingBlocks": [
{
"Type": "Compound",
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6 changes: 3 additions & 3 deletions Qualification/Workflow.m
Original file line number Diff line number Diff line change
Expand Up @@ -8,9 +8,9 @@

% --------------------------------------------------------------
% replace qualificationRunnerFolder and markdownJoinerFolder with your paths
qualificationRunnerFolder = 'C:\Software\QualificationRunner_11.0.9999';
markdownJoinerFolder = 'C:\Software\markdown-joiner_1.2.0.8';
PKSimPortableFolder = 'C:\Software\PK-Sim_11.0.9999';
qualificationRunnerFolder = 'C:\OSP\QualificationRunner 11.0.138';
markdownJoinerFolder = 'C:\OSP\markdown-joiner_1.2.0.8';
PKSimPortableFolder = 'C:\OSP\PK-Sim_11.0.150';

% --------------------------------------------------------------
% replace baseDir and qualificationPlanName with your paths
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