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Parkinson Repast Kit Model (PRKModel)

Overview

PRKModel is a MultiAgent-Based Model (MABM) designed to simulate Parkinson's disease using Repast Simphony. It models the interactions within the nervous system, including neurons, astrocytes, microglia, cytokines, and mitochondria, to study the progression of Parkinson's disease. The framework supports the collection of statistical data on the states and activities of these agents.

Key Features

• Agent-Based Design: Autonomous agents representing neurons, astrocytes, microglia, mitochondria, and cytokines.
• Simulation Environment: Built using Repast Simphony for agent-based modeling and 3D visualization.
• Data Collection: Integrated data collection for statistics on agent states and interactions.
• Biological Fidelity: Models key biological processes such as dopamine production, mitochondrial transfer, and inflammatory responses.