https://github.com/ZECTBynmo/node-vst-host
A (thin) wrapper for [MrsWatson] (https://github.com/teragonaudio/MrsWatson) that allows you to process audio files using VST plugins
npm install node-vst-host
var VSTHost = require("./node-vst-host").host;
var host = new VSTHost();
// Print our a list of the available plugins
host.listPlugins( function(names) {
console.log( "Available Plugins");
console.log( names );
});
// Process an audio file with a VST plugin
host.processAudio( "C:/inputFile.wav", "C:/outputFile.wav", ["plugin1", "plugin2"] );