diff --git a/Jenkinsfile b/Jenkinsfile
index 2b6b851d..778ca89e 100644
--- a/Jenkinsfile
+++ b/Jenkinsfile
@@ -91,6 +91,9 @@ node {
 
     populateGlobalVariables()
  try {
+          stage('Package sequila-py') {
+                sh 'bash -c "source /sequila/bin/activate && cd python && python3.6 setup.py sdist bdist_wheel &&  twine check dist/* && twine upload -r zsibio dist/* && deactivate"'
+             }
            stage('Test Scala code') {
 
                     echo 'Testing Scala code....'
diff --git a/examples/bdg-sequila.ipynb b/examples/bdg-sequila.ipynb
new file mode 100644
index 00000000..c696f618
--- /dev/null
+++ b/examples/bdg-sequila.ipynb
@@ -0,0 +1,247 @@
+{
+ "cells": [
+  {
+   "cell_type": "markdown",
+   "metadata": {},
+   "source": [
+    "import os\n",
+    "os.getcwd()\n",
+    "import sys\n",
+    "sys.path.append(\"/Users/marek/.virtualenvs/bdg-sequila/lib/python3.7/site-packages\")\n",
+    "sys.path.append(\"/Users/marek/git/forks/bdg-sequila/python\")"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 10,
+   "metadata": {},
+   "outputs": [],
+   "source": [
+    "import findspark\n",
+    "from pyspark.sql import SparkSession, DataFrame, SQLContext\n",
+    "findspark.init()"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": null,
+   "metadata": {},
+   "outputs": [],
+   "source": [
+    "from pyspark.sql import SparkSession\n",
+    "spark = SparkSession \\\n",
+    ".builder \\\n",
+    ".config('spark.ui.enabled','false') \\\n",
+    ".config('spark.driver.memory','2g') \\\n",
+    ".config('spark.driver.bindAddress', 'localhost')  \\\n",
+    ".config('spark.driver.host', 'localhost') \\\n",
+    ".appName('SeQuiLa') \\\n",
+    ".config('spark.jars','/Users/marek/git/forks/bdg-sequila/target/scala-2.11/bdg-sequila-assembly-0.5.6-spark-2.4.3.jar')  \\\n",
+    ".getOrCreate()"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": null,
+   "metadata": {},
+   "outputs": [],
+   "source": [
+    "#config paths\n",
+    "bamPath = '/Users/marek/git/forks/bdg-sequila/src/test/resources/NA12878.slice.bam'\n",
+    "vcfPath = '/Users/marek/git/forks/bdg-sequila/src/test/resources/vcf/test.vcf'"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 12,
+   "metadata": {},
+   "outputs": [],
+   "source": [
+    "#register sequila.py\n",
+    "from sequila import SequilaSession\n",
+    "ss = SequilaSession(spark)"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 13,
+   "metadata": {},
+   "outputs": [
+    {
+     "data": {
+      "text/plain": [
+       "DataFrame[]"
+      ]
+     },
+     "execution_count": 13,
+     "metadata": {},
+     "output_type": "execute_result"
+    }
+   ],
+   "source": [
+    "# create table\n",
+    "tableNameBAM =  'test'\n",
+    "ss.sql(f'CREATE TABLE {tableNameBAM} \\\n",
+    "USING org.biodatageeks.datasources.BAM.BAMDataSource \\\n",
+    "OPTIONS(path \"{bamPath}\")')"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 14,
+   "metadata": {},
+   "outputs": [
+    {
+     "name": "stdout",
+     "output_type": "stream",
+     "text": [
+      "+--------+----------+-----+---+-----+----+--------------------+--------------------+-----+----------+---------+\n",
+      "|sampleId|contigName|start|end|cigar|mapq|               baseq|            sequence|flags|materefind|SAMRecord|\n",
+      "+--------+----------+-----+---+-----+----+--------------------+--------------------+-----+----------+---------+\n",
+      "| NA12878|      chr1|   34|109|  76M|   2|ACCCADEFFECEFGGFD...|CCCTAACCCTAACCCTA...|   99|         1|     null|\n",
+      "+--------+----------+-----+---+-----+----+--------------------+--------------------+-----+----------+---------+\n",
+      "\n"
+     ]
+    }
+   ],
+   "source": [
+    "# query table\n",
+    "ss.sql(f\"SELECT * FROM {tableNameBAM} LIMIT 1\").show()"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 15,
+   "metadata": {},
+   "outputs": [
+    {
+     "name": "stdout",
+     "output_type": "stream",
+     "text": [
+      "+--------+---------+-----------+\n",
+      "|database|tableName|isTemporary|\n",
+      "+--------+---------+-----------+\n",
+      "| default|     test|      false|\n",
+      "+--------+---------+-----------+\n",
+      "\n",
+      "+--------+----------+-----+---+-----+----+--------------------+--------------------+-----+----------+---------+\n",
+      "|sampleId|contigName|start|end|cigar|mapq|               baseq|            sequence|flags|materefind|SAMRecord|\n",
+      "+--------+----------+-----+---+-----+----+--------------------+--------------------+-----+----------+---------+\n",
+      "| NA12878|      chr1|   34|109|  76M|   2|ACCCADEFFECEFGGFD...|CCCTAACCCTAACCCTA...|   99|         1|     null|\n",
+      "+--------+----------+-----+---+-----+----+--------------------+--------------------+-----+----------+---------+\n",
+      "\n"
+     ]
+    }
+   ],
+   "source": [
+    "ss.sql(\"show tables\").show()\n",
+    "ss.sql(f\"SELECT * FROM {tableNameBAM} LIMIT 1\").show()"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 16,
+   "metadata": {},
+   "outputs": [
+    {
+     "name": "stdout",
+     "output_type": "stream",
+     "text": [
+      "+----------+-----+---+--------+\n",
+      "|contigName|start|end|coverage|\n",
+      "+----------+-----+---+--------+\n",
+      "|      chr1|   34| 34|       1|\n",
+      "|      chr1|   35| 35|       2|\n",
+      "|      chr1|   36| 37|       3|\n",
+      "|      chr1|   38| 40|       4|\n",
+      "|      chr1|   41| 49|       5|\n",
+      "+----------+-----+---+--------+\n",
+      "\n"
+     ]
+    }
+   ],
+   "source": [
+    "ss.sql(f\"SELECT * FROM bdg_coverage('{tableNameBAM}','NA12878', 'blocks') LIMIT 5\").show()"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 17,
+   "metadata": {},
+   "outputs": [
+    {
+     "data": {
+      "text/plain": [
+       "DataFrame[]"
+      ]
+     },
+     "execution_count": 17,
+     "metadata": {},
+     "output_type": "execute_result"
+    }
+   ],
+   "source": [
+    "tableNameVCF =  'test_vcf'\n",
+    "ss.sql(f'CREATE TABLE {tableNameVCF} \\\n",
+    "USING org.biodatageeks.datasources.VCF.VCFDataSource \\\n",
+    "OPTIONS(path \"{vcfPath}\")')"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 18,
+   "metadata": {},
+   "outputs": [
+    {
+     "name": "stdout",
+     "output_type": "stream",
+     "text": [
+      "+------+-----+-----+-----+---------+---+---+----+------+--------------------+---+---+---+-----+---------+\n",
+      "|contig|  pos|start| stop|       id|ref|alt|qual|filter|                info| gt| gq| dp|   hq|sample_id|\n",
+      "+------+-----+-----+-----+---------+---+---+----+------+--------------------+---+---+---+-----+---------+\n",
+      "|    20|14370|14369|14370|rs6054257|  G|  A|  29|  PASS|[ns -> 3, db -> D...|0|0| 48|  1|51,51|  NA00001|\n",
+      "|    20|14370|14369|14370|rs6054257|  G|  A|  29|  PASS|[ns -> 3, db -> D...|1|0| 48|  8|51,51|  NA00002|\n",
+      "|    20|14370|14369|14370|rs6054257|  G|  A|  29|  PASS|[ns -> 3, db -> D...|1/1| 43|  5|  .,.|  NA00003|\n",
+      "|    20|17330|17329|17330|        .|  T|  A|   3|   q10|[ns -> 3, dp -> 1...|0|0| 49|  3|58,50|  NA00001|\n",
+      "|    20|17330|17329|17330|        .|  T|  A|   3|   q10|[ns -> 3, dp -> 1...|0|1|  3|  5| 65,3|  NA00002|\n",
+      "+------+-----+-----+-----+---------+---+---+----+------+--------------------+---+---+---+-----+---------+\n",
+      "\n"
+     ]
+    }
+   ],
+   "source": [
+    "ss.sql(f\"SELECT * FROM {tableNameVCF} LIMIT 5\").show()"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 8,
+   "metadata": {},
+   "outputs": [],
+   "source": [
+    "ss.stop()"
+   ]
+  }
+ ],
+ "metadata": {
+  "kernelspec": {
+   "display_name": "bdg-sequila",
+   "language": "python",
+   "name": "bdg-sequila"
+  },
+  "language_info": {
+   "codemirror_mode": {
+    "name": "ipython",
+    "version": 3
+   },
+   "file_extension": ".py",
+   "mimetype": "text/x-python",
+   "name": "python",
+   "nbconvert_exporter": "python",
+   "pygments_lexer": "ipython3",
+   "version": "3.6.8"
+  }
+ },
+ "nbformat": 4,
+ "nbformat_minor": 2
+}
diff --git a/python/README.rst b/python/README.rst
new file mode 100644
index 00000000..e69de29b
diff --git a/python/environment.yml b/python/environment.yml
new file mode 100644
index 00000000..7dbf8608
--- /dev/null
+++ b/python/environment.yml
@@ -0,0 +1,11 @@
+name: sequila
+dependencies:
+- python=3.7
+- pytest
+- pip
+- pip:
+  - findspark
+  - pyspark==2.4.3
+  - setuptools==41.2.0 # Python packaging
+  - typeguard==2.5.0
+  - twine==2.0.0 # Pypi publishing
\ No newline at end of file
diff --git a/python/sequila/__init__.py b/python/sequila/__init__.py
new file mode 100644
index 00000000..e36a22ea
--- /dev/null
+++ b/python/sequila/__init__.py
@@ -0,0 +1 @@
+from sequila.sequila import *
diff --git a/python/sequila/sequila.py b/python/sequila/sequila.py
new file mode 100644
index 00000000..deca3b96
--- /dev/null
+++ b/python/sequila/sequila.py
@@ -0,0 +1,48 @@
+from pyspark.sql import SparkSession
+from typeguard import check_argument_types
+
+
+def register(session: SparkSession):
+    """
+    register(session)
+
+    Register SQL extensions for a Spark session.
+
+    :param session: Spark session
+    """
+    assert check_argument_types()
+    sparkSession = session._jvm.org.apache.spark.sql.SparkSession.builder().enableHiveSupport().getOrCreate()
+    ss = session._jvm.org.apache.spark.sql.SequilaSession(sparkSession)
+    session._jvm.org.biodatageeks.utils.SequilaRegister.register(ss)
+    session._jvm.org.biodatageeks.utils.UDFRegister.register(ss)
+    return
+
+
+class  SequilaSession (SparkSession):
+    def __init__(self, session: SparkSession, jsparkSession=None):
+        """Creates a new SequilaSession.
+
+        """
+        ss = session._jvm.org.apache.spark.sql.SequilaSession(session._jsparkSession)
+        session._jvm.org.biodatageeks.utils.SequilaRegister.register(ss)
+        session._jvm.org.biodatageeks.utils.UDFRegister.register(ss)
+        session._jvm.SequilaSession.setDefaultSession(ss)
+        sequilaSession = SequilaSession._instantiatedSession
+        from pyspark.sql.context import SQLContext
+        self._sc = sequilaSession._sc
+        self._jsc = self._sc._jsc
+        self._jvm = session._jvm
+        if jsparkSession is None:
+            if self._jvm.SequilaSession.getDefaultSession().isDefined() \
+                    and not self._jvm.SequilaSession.getDefaultSession().get() \
+                    .sparkContext().isStopped():
+                jsparkSession = self._jvm.SequilaSession.getDefaultSession().get()
+            else:
+                jsparkSession = self._jvm.SequilaSession(self._jsc.sc())
+        self._jsparkSession = jsparkSession
+        self._jwrapped = self._jsparkSession.sqlContext()
+        self._wrapped = SQLContext(self._sc, self, self._jwrapped)
+        if SequilaSession._instantiatedSession is None \
+                or SequilaSession._instantiatedSession._sc._jsc is None:
+            SequilaSession._instantiatedSession = self
+            self._jvm.SparkSession.setDefaultSession(self._jsparkSession)
diff --git a/python/setup.py b/python/setup.py
new file mode 100644
index 00000000..ec267a64
--- /dev/null
+++ b/python/setup.py
@@ -0,0 +1,22 @@
+from setuptools import setup
+
+setup(
+    name='sequila.py',
+    version='0.1.0',
+    packages=['sequila'],
+    install_requires=[
+        'typeguard==2.5.0',
+        'pyspark==2.4.3',
+        'findspark'
+    ],
+    author='biodatageeks.org',
+    description='A SQL-based solution for large-scale genomic analysis',
+    long_description=open('README.rst').read(),
+    long_description_content_type='text/x-rst',
+    license='Apache License 2.0',
+    classifiers=[
+        'Intended Audience :: Developers',
+        'Programming Language :: Python :: 3.6',
+    ],
+    url='https://github.com/ZSI-Bio/bdg-sequila'
+)
\ No newline at end of file