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Official repository for the paper: "The relationship between periodontal disease and cancer: Insights from a Systematic Literature Network Analysis"

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The relationship between periodontal disease and cancer: Insights from a Systematic Literature Network Analysis


Welcome to the official repository for the paper titled "The relationship between periodontal disease and cancer: Insights from a Systematic Literature Network Analysis". This repository contains all the necessary files for Bibliometrix. Published in the Elsevier Journal - Cancer Epidemiology.

Villar, A., Mendes, B., Viègas, M., de Aquino Alexandre, A. L., Paladini, S., & Cossatis, J. (2024). The relationship between periodontal disease and cancer: Insights from a Systematic Literature Network Analysis. Cancer Epidemiology, 91, 102595.

Table of Contents

1. Overview


This paper investigates the relationship between periodontal disease (PD) and various cancer types. It provides a comprehensive overview of the existing knowledge about the interaction between PD and carcinogenesis, explores the underlying biological mechanisms of this connection, and consider the impact of these findings on healthcare practices and future research directions. Utilizing Systematic Literature Network Analysis (SLNA), which combines bibliometric analysis with Systematic Literature Review (SLR), our study analyzes 164 documents from 2000 to 2023. Focus is placed on the 37 most globally cited papers, enabling a targeted and comprehensive analysis of the predominant research within this scope. Our review highlights that colorectal, oral, pancreatic, lung, and gastrointestinal cancers have consistent associations with periodontal disease. On the other hand, hematological, breast and prostate cancers show associations with periodontal disease, but these links are less pronounced and more variable, indicating the need for targeted research in these domains. These insights emphasize the necessity for a multidisciplinary healthcare approach, recognizing the systemic implications of periodontal health.

2. Tools

  • Bibliometix - used for multiple bibliometric analyses.
  • Scopus - used to collect academic documents.

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Official repository for the paper: "The relationship between periodontal disease and cancer: Insights from a Systematic Literature Network Analysis"

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