diff --git a/.github/workflows/PR-validation.yml b/.github/workflows/PR-validation.yml
index 0ad99721..d965b13b 100644
--- a/.github/workflows/PR-validation.yml
+++ b/.github/workflows/PR-validation.yml
@@ -151,3 +151,34 @@ jobs:
       - name: Run integration test
         run: |
           make run-integration-test
+  pipeline-aws-infra-cdk-test:
+    name: pipeline/aws_infra CDK test
+    permissions:
+      id-token: write # This is required for requesting the JWT for gaining permissions to assume the IAM role to perform AWS actions
+    runs-on: ubuntu-22.04
+    defaults:
+      run:
+        working-directory: pipeline/aws_infra
+    steps:
+    - name: Check out repository code
+      uses: actions/checkout@v4
+    - name: Setup node.js (CDK requirement)
+      uses: actions/setup-node@v4
+      with:
+        node-version: "18"
+    - name: Install CDK
+      run: npm install -g aws-cdk
+    - name: Setup Python
+      uses: actions/setup-python@v5
+      with:
+        python-version: "3.12"
+    - name: Install CDK stack dependencies
+      run: pip install -r requirements.txt
+    - name: AWS credentials configuration
+      uses: aws-actions/configure-aws-credentials@v4
+      with:
+        role-to-assume: ${{secrets.GH_ACTIONS_AWS_ROLE}}
+        role-session-name: gh-actions-${{github.run_id}}.${{github.run_number}}.${{github.run_attempt}}-cdk-test
+        aws-region: us-east-1
+    - name: cdk diff
+      run: cdk diff
diff --git a/pipeline/aws_infra/.gitignore b/pipeline/aws_infra/.gitignore
new file mode 100644
index 00000000..64699e47
--- /dev/null
+++ b/pipeline/aws_infra/.gitignore
@@ -0,0 +1,22 @@
+*.swp
+package-lock.json
+__pycache__
+.pytest_cache
+*.egg-info
+
+## Environments
+.env
+.venv
+env/
+venv/
+ENV/
+env.bak/
+venv.bak/
+
+# CDK asset staging directory
+.cdk.staging
+cdk.out
+
+# CDK CLI installation artifacts
+node_modules/
+package.json
diff --git a/pipeline/aws_infra/README.md b/pipeline/aws_infra/README.md
new file mode 100644
index 00000000..9cef0785
--- /dev/null
+++ b/pipeline/aws_infra/README.md
@@ -0,0 +1,96 @@
+
+# AGR PAVI infra using CDK (Python)
+
+This is the AWS infrastructure component of the AGR PAVI application.
+This includes all AWS resources and infrastructure required to make the main
+application executable in AWS, and is defined and deployed using
+AWS CDK and written as Python code in this subdirectory.
+
+AWS CDK is an open-source framework that enables writing
+the entire cloud application as code, including all event sources and other AWS resources
+which are require to make the application executable in AWS in addition to the application code.
+This allows for an easy and reproducible deployment, that can be fully documented and versioned as code.
+
+For instructions on how to install the AWS CDK CLI,
+see the [AWS docs](https://docs.aws.amazon.com/cdk/v2/guide/getting_started.html#getting_started_install).
+
+CDK CLI tool used for this repository is tested and deployed using node.js v18.
+
+
+As this project is set up as a Python project, it is advised to use [virtualenv](https://docs.python.org/3/library/venv.html)
+to allow isolated dependency installation. Furthermore, it is advised to store
+the virtual env in a `venv` subdirectory in this directory.
+As this path was added to the .gitignore file, it will automatically be excluded
+from any git operations.
+
+To create a new virtual environment (for first first time use of this directory):
+```bash
+$ python3 -m venv venv
+```
+
+Then for every subsequent use of this directory (for coding, deployment, ...)
+
+First activate the virtualenv:
+```bash
+$ source venv/bin/activate
+```
+
+Once the virtualenv is activated, install the required dependencies:
+```bash
+$ pip install -r requirements.txt
+```
+
+After that, you can execute all required CDK commands as described in below chapters.
+Once done working with the code in this directory, deactivate the virtualenv:
+```bash
+$ deactivate
+```
+
+## Important files
+Two standard CDK configuration files can be found at the root level of this directory:
+ * [cdk.json](./cdk.json)
+    Contains the main CDK execution configuration parameters
+ * [cdk.context.json](./cdk.context.json)
+    Contains the VPC context in which to deploy the CDK Stack.
+
+Then the AWS Stack to be deployed using CDK is define in the following files and directories:
+ * [cdk_app.py](./cdk_app.py)
+    The root level CDK application, defining the entire AWS Stack to be deployed.
+ * [cdk_classes/](./cdk_classes/)
+    Python sub-classes defining the CDK stack (representing a single CloudFormation stack)
+    and all individual CDK constructs, representing individual cloud components.
+
+## Validating
+When making changes to any of the CDK files, validate them before requesting a PR
+or attempting a deployment, by running the following command:
+```bash
+> cdk diff
+```
+This will attempt to synthesize the (Cloudformation) stack and produce errors when (syntax) errors
+would be present in any of the CDK code.  
+When no (more) errors are present, `cdk diff` will compare the stack to the deployed stack,
+and display the changes that would get deployed. Inspect these changes to ensure
+the code changes made will have the expected effect on the deployed AWS resources.
+
+This allows the developer to fix any errors before deployment, reducing the amount of
+troubleshooting that would otherwise be required on failing or incorrect deployments.
+
+## Deployment
+After making all necessary changes to the CDK code and [validating](#validating)
+the resulting stack changes are as expected, you can deploy
+the new stack to AWS by running the following command:
+```bash
+# This command will interactively ask for confirmation before deploying security-sensitive changes.
+# To disable this approval (e.g. for use in CI/CD pipelines), add "--require-approval never"
+> cdk deploy
+```
+Any code pushed to the main branch of this repository (both main application and CDK code)
+automatically gets built and deployed, through [github actions](./.github/workflows/main-build-and-deploy.yml).
+
+## Other useful CDK commands
+Here's a list of the most useful CDK commands. For a full list, call `cdk help`.
+ * `cdk ls`          list all stacks in the app
+ * `cdk synth`       emits the synthesized CloudFormation template
+ * `cdk deploy`      deploy this stack to AWS
+ * `cdk diff`        compare deployed stack with current state
+ * `cdk docs`        open CDK documentation
diff --git a/pipeline/aws_infra/cdk.context.json b/pipeline/aws_infra/cdk.context.json
new file mode 100644
index 00000000..a31b3c72
--- /dev/null
+++ b/pipeline/aws_infra/cdk.context.json
@@ -0,0 +1,81 @@
+{
+  "vpc-provider:account=100225593120:filter.vpc-id=vpc-55522232:region=us-east-1:returnAsymmetricSubnets=true": {
+    "vpcId": "vpc-55522232",
+    "vpcCidrBlock": "172.31.0.0/16",
+    "availabilityZones": [],
+    "subnetGroups": [
+      {
+        "name": "Public",
+        "type": "Public",
+        "subnets": [
+          {
+            "subnetId": "subnet-3ebf4477",
+            "cidr": "172.31.0.0/20",
+            "availabilityZone": "us-east-1a",
+            "routeTableId": "rtb-c63af6a0"
+          },
+          {
+            "subnetId": "subnet-df7c7487",
+            "cidr": "172.31.16.0/20",
+            "availabilityZone": "us-east-1b",
+            "routeTableId": "rtb-c63af6a0"
+          },
+          {
+            "subnetId": "subnet-81c95ee4",
+            "cidr": "172.31.64.0/20",
+            "availabilityZone": "us-east-1c",
+            "routeTableId": "rtb-c63af6a0"
+          },
+          {
+            "subnetId": "subnet-ff838bd5",
+            "cidr": "172.31.48.0/20",
+            "availabilityZone": "us-east-1d",
+            "routeTableId": "rtb-c63af6a0"
+          },
+          {
+            "subnetId": "subnet-af62dca3",
+            "cidr": "172.31.80.0/20",
+            "availabilityZone": "us-east-1f",
+            "routeTableId": "rtb-c63af6a0"
+          }
+        ]
+      },
+      {
+        "name": "Private",
+        "type": "Private",
+        "subnets": [
+          {
+            "subnetId": "subnet-0d4703177afb1797d",
+            "cidr": "172.31.96.0/24",
+            "availabilityZone": "us-east-1a",
+            "routeTableId": "rtb-05e12b551f60b37ed"
+          },
+          {
+            "subnetId": "subnet-04262fc338f638054",
+            "cidr": "172.31.97.0/24",
+            "availabilityZone": "us-east-1b",
+            "routeTableId": "rtb-05e12b551f60b37ed"
+          },
+          {
+            "subnetId": "subnet-044457c061edf85f2",
+            "cidr": "172.31.98.0/24",
+            "availabilityZone": "us-east-1c",
+            "routeTableId": "rtb-05e12b551f60b37ed"
+          },
+          {
+            "subnetId": "subnet-04019d42d5c9e6fb9",
+            "cidr": "172.31.99.0/24",
+            "availabilityZone": "us-east-1d",
+            "routeTableId": "rtb-05e12b551f60b37ed"
+          },
+          {
+            "subnetId": "subnet-049778993fb504a7c",
+            "cidr": "172.31.101.0/24",
+            "availabilityZone": "us-east-1f",
+            "routeTableId": "rtb-05e12b551f60b37ed"
+          }
+        ]
+      }
+    ]
+  }
+}
diff --git a/pipeline/aws_infra/cdk.json b/pipeline/aws_infra/cdk.json
new file mode 100644
index 00000000..4dee0039
--- /dev/null
+++ b/pipeline/aws_infra/cdk.json
@@ -0,0 +1,39 @@
+{
+  "app": "python3 cdk_app.py",
+  "watch": {
+    "include": [
+      "**"
+    ],
+    "exclude": [
+      "README.md",
+      "cdk*.json",
+      "requirements*.txt",
+      "**/__init__.py",
+      "python/__pycache__",
+      "tests"
+    ]
+  },
+  "context": {
+    "@aws-cdk/aws-apigateway:usagePlanKeyOrderInsensitiveId": true,
+    "@aws-cdk/core:stackRelativeExports": true,
+    "@aws-cdk/aws-rds:lowercaseDbIdentifier": true,
+    "@aws-cdk/aws-lambda:recognizeVersionProps": true,
+    "@aws-cdk/aws-lambda:recognizeLayerVersion": true,
+    "@aws-cdk/aws-cloudfront:defaultSecurityPolicyTLSv1.2_2021": true,
+    "@aws-cdk-containers/ecs-service-extensions:enableDefaultLogDriver": true,
+    "@aws-cdk/aws-ec2:uniqueImdsv2TemplateName": true,
+    "@aws-cdk/core:checkSecretUsage": true,
+    "@aws-cdk/aws-iam:minimizePolicies": true,
+    "@aws-cdk/aws-ecs:arnFormatIncludesClusterName": true,
+    "@aws-cdk/core:validateSnapshotRemovalPolicy": true,
+    "@aws-cdk/aws-codepipeline:crossAccountKeyAliasStackSafeResourceName": true,
+    "@aws-cdk/aws-s3:createDefaultLoggingPolicy": true,
+    "@aws-cdk/aws-sns-subscriptions:restrictSqsDescryption": true,
+    "@aws-cdk/aws-apigateway:disableCloudWatchRole": true,
+    "@aws-cdk/core:enablePartitionLiterals": true,
+    "@aws-cdk/core:target-partitions": [
+      "aws",
+      "aws-cn"
+    ]
+  }
+}
diff --git a/pipeline/aws_infra/cdk_app.py b/pipeline/aws_infra/cdk_app.py
new file mode 100644
index 00000000..cead0240
--- /dev/null
+++ b/pipeline/aws_infra/cdk_app.py
@@ -0,0 +1,13 @@
+#!/usr/bin/env python3
+import os
+
+import aws_cdk as cdk
+
+from cdk_classes.cdk_infra_stack import CdkInfraStack
+
+
+app = cdk.App()
+CdkInfraStack(app, "PaviPipelineCdkStack",
+	env=cdk.Environment(account='100225593120', region='us-east-1'))
+
+app.synth()
diff --git a/pipeline/aws_infra/cdk_classes/cdk_infra_stack.py b/pipeline/aws_infra/cdk_classes/cdk_infra_stack.py
new file mode 100644
index 00000000..2603229d
--- /dev/null
+++ b/pipeline/aws_infra/cdk_classes/cdk_infra_stack.py
@@ -0,0 +1,14 @@
+from aws_cdk import (
+	Stack
+)
+
+from constructs import Construct
+
+from cdk_classes.pipeline_stack import PipelineSeqRetrievalEcrRepository
+
+class CdkInfraStack(Stack):
+
+	def __init__(self, scope: Construct, construct_id: str, **kwargs) -> None:
+		super().__init__(scope, construct_id, **kwargs)
+
+		PipelineSeqRetrievalEcrRepository(self)
diff --git a/pipeline/aws_infra/cdk_classes/pipeline_stack.py b/pipeline/aws_infra/cdk_classes/pipeline_stack.py
new file mode 100644
index 00000000..da439ba6
--- /dev/null
+++ b/pipeline/aws_infra/cdk_classes/pipeline_stack.py
@@ -0,0 +1,19 @@
+from aws_cdk import (
+    Stack,
+    aws_ecr as ecr,
+    RemovalPolicy
+)
+
+class PipelineSeqRetrievalEcrRepository:
+
+    repository: ecr.Repository
+
+    def __init__(self, scope: Stack) -> None:
+
+        # Create the ECR repository
+        repo = ecr.Repository(scope, "PAVI-pipeline-seq-retrieval-repo", repository_name='agr_pavi/seq_retrieval',
+                              empty_on_delete=False,removal_policy=RemovalPolicy.RETAIN)
+        self.repository = repo
+
+    def get_repo_arn(self) -> str:
+        return self.repository.repository_arn
diff --git a/pipeline/aws_infra/requirements-dev.txt b/pipeline/aws_infra/requirements-dev.txt
new file mode 100644
index 00000000..269f9b06
--- /dev/null
+++ b/pipeline/aws_infra/requirements-dev.txt
@@ -0,0 +1 @@
+pytest==8.0.*
diff --git a/pipeline/aws_infra/requirements.txt b/pipeline/aws_infra/requirements.txt
new file mode 100644
index 00000000..d32f0af1
--- /dev/null
+++ b/pipeline/aws_infra/requirements.txt
@@ -0,0 +1,2 @@
+aws-cdk-lib==2.136.*
+constructs==10.0.0,<11.0.0