v0.7.1

Changed

• Rewrite internal Sequence code using inlined functions to increase performance when the strand is known.

Fixed

• Nodes.copy potentially failing on empty collections after trying to allocate 0 bytes.
• TestGenes.test_write_scores failing on some machines because of float rounding issues.
• Gene.translate ignoring the unknown_residue argument value and always using "X".
• Memory leak in Pyrodigal.train cause by memory not being freed after building the GC frame plot.

v0.7.0

Added

• Support for setting a custom minimum gene length in pyrodigal.OrfFinder.
• Genes.write_scores method to write the node scores to a file.
• Gene.__repr__ and Node.__repr__ methods to display some useful attributes.
• Sequence.__str__ method to get back a nucleotide string from a Sequence object.

Changed

• Use a more compact data structure to store Gene data.

Fixed

• Nodes._calc_orf_gc reading nucleotides after the sequence end when computing GC content for edge nodes.

Removed

• pyrodigal.Pyrodigal class (use pyrodigal.OrfFinder instead).
• pyrodigal.Predictions class (functionality merged into pyrodigal.Genes).

0.6.4

Added

• load and dump methods to TrainingInfo for storing and loading a raw training info structure.
• Support for creating an OrfFinder pre-configured with a training info.
• -t and -n flags to the CLI.

0.6.3

Added

• pyrodigal command line script exposing a CLI mimicking the original prodigal binary.
• write_gff, write_genes and write_translations methods to pyrodigal.Predictions to write the predictions results to a file in different formats.
• Implementation for masking regions of unknown nucleotides in input sequences.

Changed

• Renamed pyrodigal.Pyrodigal class to pyrodigal.OrfFinder.

Fixed

• setup.py build different SIMD implementations with the same set of feature flags, causing compilers to re-optimize the SIMD implementations.

0.6.2

Added

• Sphinx documentation with small install guide and API reference.

Fixed

• setup.py not detecting SSE2 and AVX2 build support because of a linker error.

Changed

• Build OSX extension without AVX2 support since runtime detection of AVX2 to avoid the Illegal Instruction: 4 bug on older CPUs.

0.6.1

Fixed

• Source distribution lacking C files necessary for building cpu_features.

0.6.0

Added

• SIMD code to build an index of which connections can be skipped when scoring node connections in the dynamic programming routine (#6).

0.5.4

Added

• Prediction.confidence method to compute the confidence for a prediction like reported in Prodigal's GFF output.
• Prediction.sequence method get the nucleotide sequence of a predicted gene (#4).

Changed

• Replaced internal storage of input sequences to use a byte array instead of a bitmap.

Fixed

• Extract Prediction.gc_cont number directly from the start node instead of the text representation to get full accuracy.
• Prodigal bug causing nodes on the reverse strand to always receive a penalty instead of penalizing only small ORFs (hyattpd/Prodigal#88).

0.5.3

Fixed

• Prediction.translate not translating the last unknown codon properly for genes on the direct strand.

0.5.2

Changed

• Make Pyrodigal.train return a reference to the newly created TrainingInfo for inspection if needed.
• Reimplement add_nodes and add_genes to use a growable array instead of counting and pre-allocating the C arrays.

Fixed

• Inconsistent handling of unknown nucleotides in input sequences and gene translations.