-
Notifications
You must be signed in to change notification settings - Fork 0
/
hugo.yaml
224 lines (211 loc) · 7.11 KB
/
hugo.yaml
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
baseURL: ''
title: Bhardwaj Lab
languageCode: en-us
DefaultContentLanguage: en
enableEmoji: true
enableGitInfo: true
enableRobotsTXT: true
canonifyURLs: true
paginate: 9
darkmode_js:
- assets/js/darkmode.js
enableInlineShortcodes: true
markup:
goldmark:
extensions:
definitionList: true
footnote: true
linkify: true
linkifyProtocol: https
strikethrough: true
table: true
taskList: true
typographer:
apostrophe: '’'
disable: false
ellipsis: '…'
emDash: '—'
enDash: '–'
leftAngleQuote: '«'
leftDoubleQuote: '“'
leftSingleQuote: '‘'
rightAngleQuote: '»'
rightDoubleQuote: '”'
rightSingleQuote: '’'
parser:
attribute:
block: false
title: true
autoHeadingID: true
autoHeadingIDType: github
wrapStandAloneImageWithinParagraph: true
renderer:
hardWraps: false
unsafe: true
xhtml: false
params:
author: Bhardwaj Lab
authorimage: images/global/bhardwajlab_logo.svg
moto: "Quantitative Biology and Data Integration"
linktext: Institute of Biodynamics and Biocomplexity, Utrecht University
link: https://www.uu.nl/en/organisation/institute-of-biodynamics-and-biocomplexity
headimage: images/pages/multiUMAP_web.png
disable_theme_toggle: false
disable_stay_uptodate: false
p1:
heading: "Our mission"
image: "images/pages/web_slides_p1.png"
content:
- text: "The long-term goal of our lab is to transform human medicine by enabling technologies for in-vivo, directed (re)programming of stem cells into specialized cell types."
- text: "To acheive this, we need to develop a strong understanding of the fundamental mechanisms that guide the fate decisions for 'naive' stem and pluripotent cells inside our body. During development of an embryo, these cells, which share their genetic code, start to diversify in their 'epigenetic' landscapes. Guided by the regulatory proteins (transcription factors) and their chromatin environment, these cells change their identity in order to perform specific tasks."
- text: "By learning the quantitative, dose-response relationship between the epigenetic factors and the decision making process of the cells, we would be able to efficiently reprogram the stem cells into a desired cell type. We can use this understanding to build therapies towards regenerative medicine, healthy aging and cancer."
links:
- text: Learn more about epigenetic reprogramming
url: "#"
p2:
heading: "Our approach"
image: "images/pages/web_slides_p2.png"
content:
- text: "In recent years, several experimental methods have been developed to systematically map the chromatin environment of individual cells, and quantify the gene expression levels of transcription factors. This allows us to build data-driven models that explain the role of these proteins in cellular decision-making."
- text: "In our research group, we apply such experimental methods (specifically, single-cell and single-molecule genomics technologies) to understand cellular decision-making. These methods produce large scale data, typically measuring thousands of genes over thousands of cells, molecules, or samples. We use these datasets to develop statistical and machine learning models that can explain the relationship between the regulators (transcription factors, chromatin state), and a cell's current or future state."
links:
- text: Learn more about our technologies
url: "#"
p3:
heading: "Our Projects"
content:
- text: "We apply a data-driven biology approach to our projects. Half of our work is focussed on extracting new insights from quantitative epigenomics and multi-omics data of developing cells, with the aim to learn new mechanistic models of cell identity and function. The rest half of our work is focussed on building new bioinformatic methods and tools to analyse the data from such technologies, and making them available to biologists."
links:
- text: Learn more about our projects
url: "posts/news-post-1/"
image: "images/pages/vblab_projects.png"
logos:
- identifier: a
image: "images/global/sample-logo.svg"
alt: "a"
- identifier: b
p4:
heading: "News"
maxposts: 3
content:
- text: "Latest developments from our lab"
p5:
heading: "Stay Up to Date"
content:
- text: "Subscribe to our lab updates/open positions"
action: "https://formsubmit.co/3a6fe8a418a1fbfb7903d5859ca739da"
label: "Email address"
placeholder: "Enter your email"
button: "Notify me"
social_media:
github:
enabled: true
url: 'https://github.com/bhardwaj-lab'
twitter:
enabled: true
url: 'https://twitter.com/vivekbhr'
google_scholar:
enabled: true
url: 'https://scholar.google.com/citations?user=gDipTycAAAAJ&hl=en'
University:
enabled: true
name: Utrecht University
url: 'https://www.uu.nl/en/'
menu:
main:
- identifier: about
name: About
url: "#"
weight: 10
- identifier: team
name: Team
url: /team/
weight: 20
- identifier: publications
name: Publications
url: /publications/
weight: 30
- identifier: news
name: News
url: /categories/news
weight: 40
- identifier: dropdown
pre: complexdropdown
name: More
weight: 50
# pre: dropdown
dropdown:
- identifier: software
pre: stars # can be stars, comments or piechart
name: Software
post: "Open-source software from our lab"
url: "https://github.com/bhardwaj-lab"
weight: 10
- identifier: protocols
pre: stars # can be stars, comments or piechart
name: Protocols
post: "Check out our wet-lab protocols"
url: "#"
weight: 20
- identifier: datasets
pre: piechart # can be stars, comments or piechart
name: Datasets
post: "Access datasets from our lab"
url: "#"
weight: 30
- identifier: vacancy
pre: comments # can be stars, comments or piechart
name: Open positions
post: "Join us"
url: "/open_positions/"
weight: 40
footer:
- identifier: about
name: About
url: "#"
weight: 10
- identifier: blog
name: Blog
url: /categories/blog/
weight: 20
- identifier: news
name: News
url: /categories/news/
weight: 30
- identifier: contact
name: Contact
url: /contact/
weight: 50
markup:
goldmark:
renderer:
unsafe: true
taxonomies:
category: Categories
tag: Tags
privacy:
disqus:
disable: false
googleAnalytics:
anonymizeIP: true
disable: false
respectDoNotTrack: false
useSessionStorage: false
instagram:
disable: false
simple: false
twitter:
disable: false
enableDNT: false
simple: false
vimeo:
disable: false
enableDNT: false
simple: false
youtube:
disable: false
privacyEnhanced: true
module:
hugoVersion:
extended: true
min: "0.104.0"