README.md

Hello, I am Bonaventure Dossou. This is the official repository of my Master's Thesis at Jacobs University Bremen

DeepSNPs: Deep Learning for Single Nucleotide Polymorphism Disease Classification based on Chromosome Location

Raw Datasets

• GWAS Catalog
• DisGeNET
• CTCF Binding Sites

Ready-to-go

• Filtered (preprocessed) datasets used for to build (train) DeepSNPs
• Official Training Notebook

Deep Learning Model: Bidirectional LSTM using Keras Tensorflow

• Overall Workflow Picture

• Models's weights could be accessed here

• Results:

  • Training Loss (Accuracy): 0.1947 (0.9016)
  • Validation Loss (Accuracy): 1.5455 (0.7151)
  • Testing Loss (Accuracy): 0.1963 (0.9036)
  • AUC ROC: 0.8733

• Classification Report

• Confusion Matrix

• AUC ROC Curve

• Features Importance with correct predictions

• Features Importance with wrong predictions