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Musculoskeletal MRI: diffusion tensor imaging, tractography, orientation distribution function, elevation and pennation angle, torsional shear models, with data set available

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From the channel: https://www.youtube.com/@jmriismrm5389

Cyril Tous - Characterizing Myoarchitecture of the Supraspinatus / Infraspinatus With MRI DTI :

https://www.youtube.com/watch?v=2LvwYVPjPp0

TITLE: Characterizing the Myoarchitecture of the Supraspinatus and Infraspinatus Muscles With MRI Using Diffusion Tensor Imaging

ABSTRACT: Background: The societal cost of shoulder disabilities in our aging society keeps rising. Providing biomarkers of early changes in the microstructure of rotator cuff (RC) muscles might improve surgical planning. Elevation angle (E1A) and pennation angle (PA) assessed by ultrasound change with RC tears. Furthermore, ultrasounds lack repeatability.

Purpose: To propose a repeatable framework to quantify the myocyte angulation in RC muscles.

Study type: Prospective.

Subjects: Six asymptomatic healthy volunteers (1 female aged 30 years; 5 males, mean age 35 years, range 25-49 years), who underwent three repositioned scanning sessions (10 minutes apart) of the right infraspinatus muscle (ISPM) and supraspinatus muscle (SSPM).

Field strength/sequence: 3-T, T1-weighted and diffusion tensor imaging (DTI; 12 gradient encoding directions, b-values of 500 and 800 s/mm2 ).

Assessment: Each voxel was binned in percentage of depth defined by the shortest distance in the antero-posterior direction (manual delineation), i.e. the radial axis. A second order polynomial fit for PA across the muscle depth was used, while E1A described a sigmoid across depth:E1Asig=E 1Arange × sigmf(1:100% depth,(−EA1grad,E1Aasym))+E1Ashift.

Statistical tests: Repeatability was assessed with the nonparametric Wilcoxon's rank-sum test for paired comparisons across repeated scans in each volunteer for each anatomical muscle region and across repeated measures of the radial axis. A P-value ˂0.05 was considered statistically significant.

Results: In the ISPM, E1A was constantly negative, became helicoidal, then mainly positive across the antero-posterior depth, respective at the caudal, central and cranial regions. In the SSPM, posterior myocytes ran more parallel to the intramuscular tendon (PA≈0°), while anterior myocytes inserted with a pennation angle (PA≈−20°). E1A and PA were repeatable in each volunteer (error ˂ 10%). Intra-repeatability of the radial axis was achieved (error ˂ 5%).

Data conclusion: ElA and PA in the proposed framework of the ISPM and SSPM are repeatable with DTI. Variations of myocyte angulation in the ISPM and SSPM can be quantified across volunteers.

Evidence level: 2 TECHNICAL EFFICACY: Stage 2.

Keywords: angle; diffusion tensor imaging; elevation; pennation; rotator cuff tears; tractography.

© 2023 The Authors. Journal of Magnetic Resonance Imaging published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.

(https://onlinelibrary.wiley.com/doi/10.1002/jmri.28840)

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Musculoskeletal MRI: diffusion tensor imaging, tractography, orientation distribution function, elevation and pennation angle, torsional shear models, with data set available

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