diff --git a/test/test_datatypes.py b/test/test_datatypes.py
index 11929cef..86062d75 100644
--- a/test/test_datatypes.py
+++ b/test/test_datatypes.py
@@ -2,6 +2,8 @@
 from pytest import raises, skip, mark
 from .support import setup_make, pylong, pyunicode, IS_CLANG_REPL, IS_MAC_X86, IS_MAC_ARM
 
+IS_MAC = IS_MAC_X86 or IS_MAC_ARM
+
 currpath = py.path.local(__file__).dirpath()
 test_dct = str(currpath.join("datatypesDict"))
 
@@ -1274,7 +1276,7 @@ def run(self, f, buf, total):
         if self.has_byte:
             run(self, cppyy.gbl.sum_byte_data, buf, total)
 
-    @mark.xfail(run=not IS_CLANG_REPL, reason="Crashes")
+    @mark.xfail(run=not(((IS_CLANG_REPL and IS_MAC) or (not IS_CLANG_REPL and IS_MAC))), reason="Crashes")
     def test26_function_pointers(self):
         """Function pointer passing"""
 
@@ -1337,7 +1339,7 @@ def sum_in_python(i1, i2, i3):
         ns = cppyy.gbl.FuncPtrReturn
         assert ns.foo()() == "Hello, World!"
 
-    @mark.xfail(run=not IS_CLANG_REPL, reason="Crashes")
+    @mark.xfail(run=not(((IS_CLANG_REPL and IS_MAC) or (not IS_CLANG_REPL and IS_MAC))), reason="Crashes")
     def test27_callable_passing(self):
         """Passing callables through function pointers"""
 
@@ -1483,7 +1485,7 @@ def pyd(arg0, arg1):
         gc.collect()
         raises(TypeError, c, 3, 3) # lambda gone out of scope
 
-    @mark.xfail(condition=IS_MAC_X86 or IS_MAC_ARM, reason="Fails on OS X")
+    @mark.xfail(condition=IS_MAC, reason="Fails on OS X")
     def test29_std_function_life_lines(self):
         """Life lines to std::function data members"""
 
@@ -2211,7 +2213,7 @@ def test44_buffer_memory_handling(self):
             assert buf1.data1[i] == 1.*i
             assert buf1.data2[i] == 2.*i
 
-    @mark.xfail(condition=IS_MAC_X86 or IS_MAC_ARM, reason="Fails on OS X")
+    @mark.xfail(condition=IS_MAC, reason="Fails on OS X")
     def test45_const_ref_data(self):
         """Proper indirection for addressing const-ref data"""
 
diff --git a/test/test_doc_features.py b/test/test_doc_features.py
index ebbf8839..cbb7615c 100644
--- a/test/test_doc_features.py
+++ b/test/test_doc_features.py
@@ -574,8 +574,9 @@ def test02_python_introspection(self):
         assert not isinstance(i, int)
         assert isinstance(i, Integer1)
 
+    @mark.xfail(run=False, condition=(IS_MAC_ARM or IS_MAC_X86) and (not IS_CLANG_REPL), reason= "Crashes on OS X Cling")
     def test03_STL_containers(self):
-        """Instantiate STL contaienrs with new class"""
+        """Instantiate STL containers with new class"""
 
         from cppyy.gbl import Integer1
         from cppyy.gbl.std import vector
@@ -849,6 +850,7 @@ def test03_use_of_ctypes_and_enum(self):
         assert list(arr) == [1, 42, 1, 42]
         cppyy.gbl.free(vp)
 
+    @mark.xfail(run=False, condition=(IS_MAC_ARM or IS_MAC_X86) and (not IS_CLANG_REPL), reason= "Crashes on OS X Cling")
     def test04_ptr_ptr_python_owns(self):
         """Example of ptr-ptr use where python owns"""
 
@@ -1091,7 +1093,7 @@ def setup_class(cls):
 
         cppyy.gbl.talk_examples
 
-    @mark.xfail
+    @mark.xfail(run=not((IS_MAC_ARM or IS_MAC_X86) and not IS_CLANG_REPL))
     def test_template_instantiation(self):
         """Run-time template instantiation example"""
 
diff --git a/test/test_lowlevel.py b/test/test_lowlevel.py
index c2bf174f..1c273857 100644
--- a/test/test_lowlevel.py
+++ b/test/test_lowlevel.py
@@ -1,6 +1,6 @@
 import py, os, sys
 from pytest import raises, skip, mark
-from .support import setup_make, pylong, pyunicode, IS_WINDOWS, ispypy, IS_CLANG_REPL
+from .support import setup_make, pylong, pyunicode, IS_WINDOWS, ispypy, IS_CLANG_REPL, IS_MAC_ARM, IS_MAC_X86
 
 currpath = py.path.local(__file__).dirpath()
 test_dct = str(currpath.join("datatypesDict"))
@@ -338,7 +338,7 @@ def test09_numpy_bool_array(self):
         x = np.array([True], dtype=bool)
         assert cppyy.gbl.convert_bool(x)
 
-    @mark.xfail
+    @mark.xfail(run=not((IS_MAC_ARM or IS_MAC_X86) and not IS_CLANG_REPL))
     def test10_array_of_const_char_star(self):
         """Test passting of const char*[]"""
 
diff --git a/test/test_regression.py b/test/test_regression.py
index 8285c865..cf8a9f6c 100644
--- a/test/test_regression.py
+++ b/test/test_regression.py
@@ -185,7 +185,7 @@ def test07_class_refcounting(self):
 
         assert sys.getrefcount(x) == old_refcnt
 
-    @mark.xfail
+    @mark.xfail(run=not((IS_MAC_ARM or IS_MAC_X86) and not IS_CLANG_REPL))
     def test08_typedef_identity(self):
         """Nested typedefs should retain identity"""
 
@@ -1088,7 +1088,7 @@ def test37_array_of_pointers_argument(self):
 
             assert cppyy.addressof(res) == cppyy.addressof(arr)
 
-    @mark.xfail
+    @mark.xfail(run=not((IS_MAC_ARM or IS_MAC_X86) and not IS_CLANG_REPL))
     def test38_char16_arrays(self):
         """Access to fixed-size char16 arrays as data members"""
 
diff --git a/test/test_stltypes.py b/test/test_stltypes.py
index 52b5e0e0..764fca40 100644
--- a/test/test_stltypes.py
+++ b/test/test_stltypes.py
@@ -389,7 +389,7 @@ def test06_vector_indexing(self):
         assert v2[-1] == v[-2]
         assert v2[self.N-4] == v[-2]
 
-    @mark.xfail
+    @mark.xfail(run=not((IS_MAC_ARM or IS_MAC_X86) and not IS_CLANG_REPL))
     def test07_vector_bool(self):
         """Usability of std::vector<bool> which can be a specialization"""
 
@@ -408,7 +408,7 @@ def test07_vector_bool(self):
         assert len(vb[4:8]) == 4
         assert list(vb[4:8]) == [False]*3+[True]
 
-    @mark.xfail
+    @mark.xfail(run=not((IS_MAC_ARM or IS_MAC_X86) and not IS_CLANG_REPL))
     def test08_vector_enum(self):
         """Usability of std::vector<> of some enums"""
 
@@ -430,7 +430,7 @@ def test08_vector_enum(self):
             ve[0] = cppyy.gbl.VecTestEnumNS.EVal2
             assert ve[0] == 42
 
-    @mark.xfail(condition=IS_MAC_X86 or IS_MAC_ARM, reason="Fails on OS X")
+    @mark.xfail(run=not (IS_MAC_ARM or IS_MAC_X86), condition=IS_MAC_X86 or IS_MAC_ARM, reason="Fails on OS X")
     def test09_vector_of_string(self):
         """Adverse effect of implicit conversion on vector<string>"""
 
@@ -565,7 +565,7 @@ def test13_vector_smartptr_iteration(self):
             i += 1
         assert i == len(result)
 
-    @mark.xfail
+    @mark.xfail(run=not((IS_MAC_ARM or IS_MAC_X86) and not IS_CLANG_REPL))
     def test14_vector_of_vector_of_(self):
         """Nested vectors"""
 
@@ -625,7 +625,7 @@ def test17_vector_cpp17_style(self):
         v = cppyy.gbl.std.vector(l)
         assert list(l) == l
 
-    @mark.xfail
+    @mark.xfail(run=not((IS_MAC_ARM or IS_MAC_X86) and not IS_CLANG_REPL))
     def test18_array_interface(self):
         """Test usage of __array__ from numpy"""
 
@@ -672,7 +672,7 @@ def test18_array_interface(self):
         v = np.array(v, dtype=np.intc)
         assert ns.func(v) == sum(v)
 
-    @mark.xfail
+    @mark.xfail(run=not((IS_MAC_ARM or IS_MAC_X86) and not IS_CLANG_REPL))
     def test19_vector_point3d(self):
         """Iteration over a vector of by-value objects"""
 
diff --git a/test/test_templates.py b/test/test_templates.py
index 84dde830..c553f1e7 100644
--- a/test/test_templates.py
+++ b/test/test_templates.py
@@ -1,6 +1,6 @@
 import py, os
 from pytest import raises, mark
-from .support import setup_make, pylong, IS_CLANG_REPL, IS_CLANG_DEBUG
+from .support import setup_make, pylong, IS_CLANG_REPL, IS_CLANG_DEBUG, IS_MAC_X86, IS_MAC_ARM
 
 currpath = py.path.local(__file__).dirpath()
 test_dct = str(currpath.join("templatesDict"))
@@ -615,7 +615,7 @@ def callback(x):
 
         assert cppyy.gbl.std.function['double(std::vector<double>)']
 
-    @mark.xfail
+    @mark.xfail(run=(IS_MAC_ARM or IS_MAC_X86) and IS_CLANG_REPL)
     def test25_stdfunction_ref_and_ptr_args(self):
         """Use of std::function with reference or pointer args"""
 
@@ -1123,7 +1123,7 @@ class TNaVU;
                         run_n = getattr(cppyy.gbl, 'TNaRun_%d' % n)
                         getattr(run_n, t)
 
-    @mark.xfail
+    @mark.xfail(run=not((IS_MAC_ARM or IS_MAC_X86) and not IS_CLANG_REPL))
     def test33_using_template_argument(self):
         """`using` type as template argument"""
 
@@ -1153,7 +1153,7 @@ def test33_using_template_argument(self):
         assert ns.testptr
         assert cppyy.gbl.std.vector[ns.testptr]
 
-    @mark.xfail
+    @mark.xfail(run=not((IS_MAC_ARM or IS_MAC_X86) and not IS_CLANG_REPL))
     def test34_cstring_template_argument(self):
         """`const char*` use over std::string"""
 
@@ -1178,6 +1178,7 @@ def test34_cstring_template_argument(self):
         assert ns.stringify(ctypes.c_char_p(bytes("Noot", "ascii"))) == "Noot "
 
 
+@mark.skipif(((IS_MAC_ARM or IS_MAC_X86) and not IS_CLANG_REPL), reason="setup class fails with OS X cling")
 class TestTEMPLATED_TYPEDEFS:
     def setup_class(cls):
         cls.test_dct = test_dct
@@ -1295,6 +1296,7 @@ class A {
         assert cppyy.gbl.FailedTypeDeducer.B[int]().result()      == 5
 
 
+@mark.skipif(((IS_MAC_ARM or IS_MAC_X86) and not IS_CLANG_REPL), reason="setup class fails with OS X cling")
 class TestTEMPLATE_TYPE_REDUCTION:
     def setup_class(cls):
         cls.test_dct = test_dct