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AlexanderPico authored and github-actions[bot] committed Sep 1, 2023
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Binary file added figures/PMC10325730__fimmu-14-1179664-g005.jpg
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28 changes: 28 additions & 0 deletions figures/PMC10325730__fimmu-14-1179664-g005.yml
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---
pmcid: PMC10325730
image_filename: fimmu-14-1179664-g005.jpg
figure_link: /pmc/articles/PMC10325730/figure/f5/
number: Figure 5
figure_title: ''
caption: Significant modules and roles of PPI network (A) The top four key gene modules
identified by MCODE plug-in of Cytoscape. (B) Bubble plots of Gene ontology (GO)
enrichment for modules associated with the biological processes (GO-BP, blue), the
cellular components (GO-CC, red), and the molecular functions (GOMF, green). (C)
Bubble plots of Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis.
article_title: Exploring the potential common denominator pathogenesis of system lupus
erythematosus with COVID-19 based on comprehensive bioinformatics analysis.
citation: Huiqiong Zeng, et al. Front Immunol. 2023;14:1179664.

doi: 10.3389/fimmu.2023.1179664
journal_title: Frontiers in Immunology
journal_nlm_ta: Front Immunol
publisher_name: Frontiers Media S.A.

keywords:
- bioinformatics
- system lupus erythematosus
- COVID-19
- diagnostic biomarkers
- immune cells infiltration

---
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30 changes: 30 additions & 0 deletions figures/PMC10462626__41598_2023_40404_Fig2_HTML.yml
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---
pmcid: PMC10462626
image_filename: 41598_2023_40404_Fig2_HTML.jpg
figure_link: /pmc/articles/PMC10462626/figure/Fig2/
number: Figure 2
figure_title: ''
caption: (A) PPI network of DEGs was established by STRING (http://string-db.org)
and visualized via Cytoscape software (version 3.9.0). The red nodes indicated upregulated
genes and the blue nodes indicated downregulated genes. (B) Top 20 hub genes with
a higher degree of connectivity. (C) KEGG pathway enrichment analysis of the top
20 hub genes. (D) The prognostic value (p < 0.05) of the top 20 hub genes in CRC
patients in the disease-free survival (DFS) curve (GEPIA). (E) The expression of
ORM1 between liver metastases and primary tumors, primary tumors, and normal tissues
of CRC in datasets GSE14297, GSE49355, and GSE81558 respectively. Data are expressed
as mean ± SD. ns p ≥ 0.05, ***p < 0.001, ****p < 0.0001 (unpaired t test or ANOVA).
article_title: Orosomucoid 1 promotes colorectal cancer progression and liver metastasis
by affecting PI3K/AKT pathway and inducing macrophage M2 polarization.
citation: Lei Yue, et al. Sci Rep. 2023;13:14092.

doi: 10.1038/s41598-023-40404-1
journal_title: Scientific Reports
journal_nlm_ta: Sci Rep
publisher_name: Nature Publishing Group UK

keywords:
- Cancer
- Gastrointestinal cancer
- Metastasis

---
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33 changes: 33 additions & 0 deletions figures/PMC10462740__41598_2023_40617_Fig3_HTML.yml
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---
pmcid: PMC10462740
image_filename: 41598_2023_40617_Fig3_HTML.jpg
figure_link: /pmc/articles/PMC10462740/figure/Fig3/
number: Figure 3
figure_title: ''
caption: 'LAMP1 protein–protein interaction network reveals its role in immune regulation.
(A) KEGG-GSEA enrichment analysis of LAMP1 correlated genes on GSE6575 (upper) and
GSE18123 (lower) datasets. (B) The protein–protein interacting (PPI) network of
LAMP1 was obtained from STRING (string-db.org) and visualized using Cytoscape software
(3.8.4). (C) The top 10 hub-gene was calculated using cytoHubba plugin in software
using Maximal Clique Centrality (MCC) algorithm. (D) PPI network connectivity for
LAMP1 and DEGs genes identified as up-regulated in ASD groups constructed by STRING
(https://string-db.org/). (E) The WikiPathway enrichment analysis according to PPIs
of the STRING enrichment results. (F) Human phenotype prediction of LAMP1 using
Harmonizome database indicating as Z-score. (G) Immune cell enrichment analysis
of GSE6575 using TIMER2.0 and that correlation assay between LAMP1 mRNA expression
associations with neutrophil enrichment content was performed. KEGG: Kyoto Encyclopedia
of Genes and Genomes.'
article_title: LAMP1 as a novel molecular biomarker to predict the prognosis of the
children with autism spectrum disorder using bioinformatics approaches.
citation: Sisi Deng, et al. Sci Rep. 2023;13:14040.

doi: 10.1038/s41598-023-40617-4
journal_title: Scientific Reports
journal_nlm_ta: Sci Rep
publisher_name: Nature Publishing Group UK

keywords:
- Biomarkers
- Autism spectrum disorders

---
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29 changes: 29 additions & 0 deletions figures/PMC9751040__fimmu-13-1058884-g006.yml
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---
pmcid: PMC9751040
image_filename: fimmu-13-1058884-g006.jpg
figure_link: /pmc/articles/PMC9751040/figure/f6/
number: Figure 6
figure_title: ''
caption: Screening Hub genes. (A) PPI network diagram obtained after applying the
k-means algorithm based on machine learning to the Co-genes. The four genes in the
lower right-hand corner of the enlarged diagram are CASP1, NLRP3, IL1B, and IL18.
(B) PPI network diagram after processing with Cytoscape software. (C) The Top 11
hub genes are filtered using the Degree algorithm under the CytoHubba package condition.
article_title: SARS-CoV-2 induces “cytokine storm” hyperinflammatory responses in
RA patients through pyroptosis.
citation: Qingcong Zheng, et al. Front Immunol. 2022;13:1058884.

doi: 10.3389/fimmu.2022.1058884
journal_title: Frontiers in Immunology
journal_nlm_ta: Front Immunol
publisher_name: Frontiers Media S.A.

keywords:
- SARS-CoV-2
- COVID-19
- rheumatoid arthritis
- pyroptosis
- caspase-1
- minocycline

---
2 changes: 1 addition & 1 deletion figures/fetch.log
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https://www.ncbi.nlm.nih.gov/pmc/?term=(network-OR-PPI+cytoscape)+AND+(2023/07/01[PUBDATE]+%3A+3000/01/01[PUBDATE])&report=imagesdocsum&dispmax=100
https://www.ncbi.nlm.nih.gov/pmc/?term=(network-OR-PPI+cytoscape)+AND+(2023/08/01[PUBDATE]+%3A+3000/01/01[PUBDATE])&report=imagesdocsum&dispmax=100
4 results
2 changes: 1 addition & 1 deletion query_config.yml
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terms:
- network OR PPI
- cytoscape
last_run: 2023/08/01
last_run: 2023/09/01
date_range: ~

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