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hallmark_genes.tsv
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hallmark_genes.tsv
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HALLMARK_PANCREAS_BETA_CELLS http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_PANCREAS_BETA_CELLS PAX6 NEUROD1 ISL1 NKX2-2 PCSK1 NKX6-1 SLC2A2 SEC11A DCX SPCS1 FOXA2 GCK MAFB INS PDX1 ABCC8 IAPP SRP9 NEUROG3 FOXO1 AKT3 GCG DPP4 PAX4 SYT13 SCGN HNF1A STXBP1 CHGA VDR PCSK2 INSM1 SST ELP4 SRPRB PAK3 G6PC2 PKLR LMO2 SRP14
HALLMARK_SPERMATOGENESIS http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_SPERMATOGENESIS PDHA2 TSSK2 TNP1 ZPBP DPEP3 ADAM2 ACTL7B GAPDHS TUBA3C LDHC DDX25 PRM2 TCP11 PIAS2 PAPOLB OAZ3 PHF7 ODF1 ACRBP YBX2 CSNK2A2 NAA11 TULP2 ADAD1 SYCP1 DDX4 MLF1 TEKT2 SPATA6 PGK2 HSPA2 ACRV1 CLPB CRISP2 FAM164C AKAP4 CCNA1 CCT6B PACRG GSG1 THEG HSPA4L CST8 DCC HSPA1L GSTM3 DNAJB8 IL13RA2 CAMK4 LPIN1 ZC3H14 COIL PHKG2 KIF2C RPL39L SLC2A5 PCSK4 AURKA MLLT10 NOS1 ART3 CCNB2 NPHP1 CLGN MAST2 MTOR CDKN3 ZNRF4 AGFG1 SNAP91 PSMG1 CHFR TNP2 EZH2 HBZ ARL4A SLC12A2 BRAF VDAC3 POMC IFT88 TKTL1 NEK2 STAM2 HIST1H1T GMCL1 MTNR1A RFC4 DBF4 PRKAR2A TTK DMC1 NCAPH PEBP1 CHRM4 TOPBP1 SCG5 NEFH MAP7 BUB1 SEPT4 PGS1 NPY5R TSN CDK1 SHE PARP2 TNNI3 PCSK1N IDE GPR182 RAD17 TLE4 ACE SIRT1 HTR5A TALDO1 NF2 CLVS1 CNIH2 GRM8 STRBP ADCYAP1 ALOX15 MEP1B SCG3 GFI1 ELOVL3 IL12RB2 DMRT1 GAD1 CFTR JAM3 IP6K1 HOXB1
HALLMARK_ALLOGRAFT_REJECTION http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ALLOGRAFT_REJECTION PTPRC IL12B TGFB1 IL12A CD3E CD3D CD28 LYN HCLS1 IL18 CRTAM IFNG CD3G CD86 IL10 UBE2N BCL10 CD4 LCK NCK1 C2 HLA-A ITGB2 HLA-DQA1 CD1D CD80 HLA-DRA THY1 TLR1 HLA-G HLA-DMB IL7 IL4 TNF CD247 IL2 HLA-DMA STAT1 IRF4 SRGN INHBA TLR3 ZAP70 CD74 CD40 TRAF2 B2M BCL3 LTB IFNGR1 CCR5 CD40LG HLA-DOA GLMN IL6 HLA-E CD2 CCL5 FAS FASLG TLR6 PF4 TGFB2 CD79A INHBB ELANE SPI1 MAP3K7 IL15 CTSS CD47 PRF1 IL12RB1 LCP2 SOCS1 CDKN2A STAT4 CD7 HLA-DOB CD8A ICAM1 CCL4 GZMB CSF1 IL11 STAB1 IL2RA NLRP3 CCND3 EIF3A SIT1 IFNAR2 HDAC9 CARTPT TRAT1 CCL22 APBB1 FYB IL1B TIMP1 RPS19 JAK2 KRT1 WARS IFNGR2 CCR2 EREG MMP9 EGFR IL16 CFP WAS ITGAL KLRD1 RARS TLR2 CCND2 IL2RG ETS1 ITK NCR1 MAP4K1 CCL19 PSMB10 RPL39 EIF3J ABCE1 CD8B F2 ELF4 LY86 FCGR2B GBP2 PRKCG RPS9 MTIF2 GZMA AARS CD96 CSK HIF1A CCL2 ICOSLG NPM1 IL4R CCL11 NME1 FLNA GPR65 ACHE EIF3D IGSF6 F2R IL13 TAP1 DARS IRF7 ACVR2A CXCR3 PRKCB CXCL9 PTPN6 NCF4 UBE2D1 LIF CCR1 MBL2 DEGS1 TPD52 AKT1 RIPK2 IKBKB GCNT1 SOCS5 IRF8 TAP2 EIF4G3 ABI1 CCL7 IL2RB BRCA1 FGR IL18RAP MRPL3 CXCL13 CAPG EIF5A RPS3A GALNT1 ST8SIA4 CCL13 RPL3L LY75 TAPBP NOS2 RPL9 BCAT1 IL9 IL27RA DYRK3
HALLMARK_PEROXISOME http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_PEROXISOME ABCD3 ACOT8 ACOX1 ACSL1 ECH1 ECI2 EHHADH GSTK1 HSD17B4 MLYCD PEX11A RETSAT SLC27A2 PEX13 PEX14 SCP2 HSD3B7 GNPAT ABCD2 SLC25A17 PEX2 ACAA1 HAO2 HSD17B11 CRAT PEX11B LONP2 IDH1 FIS1 PEX6 ABCB4 SOD1 ABCB1 ISOC1 YWHAH EPHX2 ABCD1 HMGCL ACSL5 ALDH9A1 DHCR24 ELOVL5 NUDT19 PRDX5 CTPS IDE SLC23A2 PEX5 BCL10 NR1I2 TSPO CNBP MSH2 DHRS3 DIO1 SLC25A4 PRDX1 IDI1 HRAS MVP ABCC8 CLN6 CAT ACSL4 IDH2 ABCC5 SOD2 SLC35B2 FDPS ALB FADS1 STS SMARCC1 ITGB1BP1 SIAH1 SLC25A19 CDK7 RXRG ALDH1A1 UGT2B17 CADM1 SERPINA6 CLN8 RDH11 CTBP1 HSD11B2 TTR ERCC3 ATXN1 SULT2B1 CRABP2 CRABP1 TOP2A SCGB1A1 ERCC1 DLG4 PABPC1 FABP6 ABCB9 CACNA1B SEMA3C VPS4B CEL ESR2
HALLMARK_BILE_ACID_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_BILE_ACID_METABOLISM SCP2 ABCD3 SLC27A2 HSD3B7 HSD17B4 AKR1D1 ABCD2 PEX1 CYP8B1 PNPLA8 PHYH SLC27A5 CYP7B1 CYP27A1 PEX26 AGXT PEX7 CROT CYP39A1 ABCA3 CYP7A1 HACL1 PIPOX PEX6 SOD1 GNPAT HSD3B1 ABCA2 HAO1 PEX16 ABCD1 ACSL1 MLYCD ABCG8 AQP9 ISOC1 NR1H4 PEX19 NPC1 HSD17B11 AMACR CYP46A1 PEX13 IDH1 PEX11A HSD17B6 EPHX2 PRDX5 PXMP2 BBOX1 FADS2 ALDH9A1 APOA1 OPTN GSTK1 ABCG4 ALDH8A1 NR3C2 ABCA6 RETSAT FADS1 PECR PEX12 CAT GNMT ABCA9 ACSL5 LONP2 DHCR24 ABCA8 PFKM DIO1 RXRA FDXR TTR KLF1 SLC29A1 BCAR3 LCK PEX11G SLCO1A2 ALDH1A1 SULT1B1 NR1I2 GC ABCA4 SLC35B2 SLC23A1 NUDT12 ABCA1 PAOX SLC22A18 DIO2 RBP1 SLC23A2 ATXN1 GCLM NEDD4 RXRG AR BMP6 SERPINA6 LIPE EFHC1 IDH2 IDI1 CH25H ABCA5 SULT2B1 SOAT2 TFCP2L1 NR0B2
HALLMARK_IL2_STAT5_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_IL2_STAT5_SIGNALING SOCS2 CISH PIM1 IL2RA TNFRSF4 SOCS1 TNFRSF9 XBP1 RRAGD HK2 PHLDA1 IL2RB CTLA4 NFIL3 CD83 IKZF2 IL10 TNFRSF18 DHRS3 ECM1 ADAM19 SLC2A3 HIPK2 BATF3 BHLHE40 PTGER2 DENND5A ITIH5 PHTF2 GADD45B NRP1 NCOA3 CD79B AHR TNFRSF1B NDRG1 BCL2L1 GABARAPL1 LIF TIAM1 BMPR2 MAP3K8 RHOB MYC S100A1 METTL20 CAPG ST3GAL4 PENK IRF4 CST7 WLS TLR7 IKZF4 GBP4 RGS16 SPP1 IL13 SLC29A2 NFKBIZ IL4R MXD1 CSF2 FAH CTSZ ITGAE MUC1 MAPKAPK2 TNFRSF21 NT5E FLT3LG CCND2 TRAF1 LCLAT1 IL3RA CYFIP1 BCL2 FGL2 PRNP N6AMT2 PUS1 ITGAV NCS1 DCPS AMACR FAM126B PTH1R ODC1 IGF1R PTCH1 ENO3 CD81 MAFF EMP1 CDKN1C CAPN3 IL1R2 SYT11 TTC39B ANXA4 BATF P4HA1 GPR65 SLC1A5 IGF2R CKAP4 CCR4 CD44 P2RX4 GATA1 KLF6 ARL4A HOPX GPR83 ITGA6 CD48 CCDC164 SELP GLIPR2 SMPDL3A PLSCR1 FURIN SERPINB6 TNFSF11 GPX4 LRRC8C CCNE1 CASP3 SH3BGRL2 SNX9 PLEC BMP2 ICOS ALCAM LTB ENPP1 IL1RL1 MYO1C IFNGR1 PLIN2 IL18R1 AHNAK PRKCH TNFRSF8 SYNGR2 GALM POU2F1 EOMES NOP2 PTRH2 RHOH CDC6 MYO1E CXCL10 SNX14 IRF6 IL10RA MAP6 TNFSF10 SPRED2 SELL SERPINC1 CDCP1 RORA COCH CSF1 F2RL2 UCK2 CA2 IFITM3 UMPS HUWE1 COL6A1 ABCB1 RNH1 IRF8 GUCY1B3 AHCY PRAF2 GSTO1 TWSG1 CDC42SE2 PLAGL1 APLP1 AKAP2 PPAP2A SPRY4 SCN9A SHE PDCD2L CCND3 LRIG1 SWAP70 SLC39A8 RABGAP1L TGM2 PNP AGER ETV4 CD86
HALLMARK_COAGULATION http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_COAGULATION F2 PROC C1S MMP14 F10 PLG C1R SERPINE1 SERPING1 C2 F12 CFI MMP2 C3 F9 CTSO TMPRSS6 MMP9 PROZ MMP1 CFB BMP1 VWF FGA F11 THBD FURIN MMP11 F8 LGMN HPN CTSB MBL2 F13B TIMP1 CTSL2 MMP8 A2M MMP10 MASP2 FGG C8A PLAU ADAM9 GSN CAPN2 PLAT FN1 CTSH OLR1 SPARC RGN C8B LAMP2 C9 PROS1 CLU F2RL2 CD9 CFH PREP LTA4H GP9 DUSP14 CTSK GDA CASP9 APOC1 CRIP2 KLK8 SERPINC1 ANXA1 ITIH1 PRSS23 FBN1 MST1 F3 KLF7 CTSE ITGB3 CAPN5 CSRP1 KLKB1 MSRB2 TFPI2 MMP3 MEP1A GP1BA APOA1 SERPINA1 TF PEF1 GNG12 SIRT2 COMP HTRA1 MAFF LRP1 PF4 PGCP MMP15 RABIF HRG C8G APOC2 SERPINB2 RAPGEF3 CPN1 ITGA2 RAC1 DPP4 WDR1 THBS1 FYN PDGFB SH2B2 PECAM1 MMP7 DUSP6 CPB2 S100A13 CFD DCT LEFTY2 ANG C1QA HMGCS2 ISCU PLEK APOC3 P2RY1 USP11 TIMP3 ACOX2 HNF4A S100A1 GNB2 ARF4
HALLMARK_HEME_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HEME_METABOLISM ALAS2 PPOX FECH HMBS GYPB ALAD RHD GYPA SELENBP1 BLVRB GYPE GYPC EPB42 SLC4A1 RHCE RHAG TAL1 MARCH8 SPTB UROD HBQ1 DCAF11 ERMAP EIF2AK1 CPOX MPP1 GLRX5 TSPAN5 OSBP2 ANK1 NFE2 AHSP SPTA1 MAP2K3 BNIP3L SLC22A4 CLIC2 TRAK2 GCLC KEL RANBP10 TRIM10 TSPO2 UROS XK SNCA MARK3 UBAC1 CA1 CA2 BSG FOXO3 KLF1 CDC27 KAT2B NARF GCLM FBXO7 H1F0 HEBP1 HBD NUDT4 FBXO9 RAD23A CROCCP2 TMCC2 BLVRA GATA1 RBM38 PRDX2 RNF123 MINPP1 TNS1 CTSE EPB49 HDGF XPO7 MKRN1 SMOX TFDP2 MXI1 HBB MOSPD1 SLC25A37 SLC30A1 ABCB6 SLC6A8 TFRC RCL1 TOP1 EPOR TNRC6B ACSL6 GAPVD1 MGST3 SLC30A10 CAT BCAM HBZ DARC PSMD9 ISCA1 PDZK1IP1 HIST1H4C ICAM4 MOCOS ADD1 FTCD ADD2 BMP2K BPGM CLCN3 E2F2 HAGH JHDM1D OPTN RAP1GAP CTNS NFE2L1 ELL2 SLC2A1 PIGQ KLF3 EPB41 LAMP2 TMEM9B EZH1 CTSB ATG4A MFHAS1 MYL4 RNF19A BTG2 SLC11A2 ADIPOR1 ASNS DCUN1D1 ALDH1L1 DCAF10 YPEL5 SEC14L1 USP15 RIOK3 SIDT2 FOXJ2 TCEA1 VEZF1 LPIN2 PC HBBP1 CDR2 CCND3 SLC25A38 FAM46C FBXO34 BACH1 NR3C1 AQP3 TRIM58 LMO2 PICALM NCOA4 GDE1 SLC6A9 NNT ARHGEF12 PPP2R5B C3 MARCH2 UCP2 SYNJ1 FN3K ABCG2 DAAM1 AGPAT4 CCDC28A GMPS ACP5 SLC10A3 ALDH6A1 CIR1 RBM5 HTRA2 IGSF3 BTRC PGLS PQLC1 SDCBP LRP10 NEK7 ARL2BP ENDOD1 P4HA2 HTATIP2 SLC7A11 KHNYN MBOAT2 ATP6V0A1 CAST TYR
HALLMARK_UV_RESPONSE_DN http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UV_RESPONSE_DN TJP1 NFIB TGFBR3 TFPI MMP16 ABCC1 MAP2K5 AGGF1 PLCB4 MET IRS1 PTPRM AKT3 SIPA1L1 NR1D2 ATRN ANXA2 ADD3 CDKN1B ATXN1 CAP2 PRDM2 FAM179B SDC2 SMAD3 SLC7A1 GCNT1 RUNX1 RND3 PPAP2B NR3C1 YTHDC1 PPARG LPHN2 DLG1 ATP2B4 NIPBL PEX14 MYC RASA2 FZD2 BMPR1A LPAR1 PRKCA MGMT PRKCE RXRA LTBP1 LDLR RBPMS CACNA1A RGS4 COL5A2 PTPN21 PRKAR2B GJA1 BCKDHB ATP5S SERPINE1 AMPH MIOS CITED2 COL1A2 INSIG1 FYN WDR37 ZMIZ1 PMP22 CDON PIK3R3 NOTCH2 SYNJ2 SMAD7 MAP1B PAPD7 PTEN DYRK1A NEK7 SPOP F3 ERBB2 GRK5 DUSP1 VLDLR CAV1 COL11A1 CDC42BPA CDK13 SFMBT1 ADORA2B BHLHE40 COL3A1 KCNMA1 SYNE1 IGF1R CELF2 MTA1 EFEMP1 LAMC1 PHF3 SCAF8 VAV2 PIAS3 ACVR2A NRP1 MRPS31 CYR61 DAB2 MAGI2 ANXA4 COL1A1 SCHIP1 DDAH1 PDGFRB ATRX KALRN TGFBR2 PTGFR ATP2C1 ARHGEF9 NFKB1 MGLL FBLN5 PDLIM5 MAPK14 SRI INPP4B IGFBP5 ITGB3 BDNF ID1 SNAI2 SCN8A ATP2B1 FHL2 KIT APBB2 PIK3CD DLC1 MT1E DBP HAS2 SLC22A18 ICA1
HALLMARK_UV_RESPONSE_UP http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UV_RESPONSE_UP NXF1 SLC6A8 BAK1 CDC5L HSPA2 POLR2H ALAS1 TUBA4A C4BPB CCNE1 EPHX1 GRPEL1 ICAM1 FEN1 ARRB2 JUNB CTSL2 DGAT1 ATF3 CASP3 RASGRP1 TMBIM6 FOS TAP1 E2F5 RAB27A CCND3 SLC25A4 SPR CDKN2B SHOX2 OLFM1 IGFBP2 LYN CLTB BCL2L11 LHX2 NFKBIA MSX1 H2AFX NR4A1 GLS CDC34 MMP14 STK25 PDAP1 ABCB1 BSG SEPW1 IRF1 RXRB TFRC PPIF CDKN1C HLA-F CREG1 APOM BMP2 TGFBRAP1 NAT1 CYB5R1 RRAD POLE3 IL6 YKT6 ACAA1 CLCN2 EIF2C2 SOD2 PPP1R2 RHOB RET PDLIM3 EPCAM DNAJA1 SULT1A1 CHKA CYP1A1 ATP6V1F CDO1 ALDOA NPTXR EIF2S3 CNP GRINA BID POLG2 IL6ST HYAL2 FOSB MGAT1 NKX2-5 PPAT FURIN MRPL23 HTR7 CXCL2 KLHDC3 PRPF3 DNAJB1 AP2S1 PSMC3 TST SIGMAR1 GCH1 BTG2 CEBPG TARS UROD PARP2 BTG3 DLG4 CHRNA5 NPTX2 ATP6V1C1 AQP3 PLCL1 NUPL1 TYRO3 HMOX1 RPN1 BTG1 FMO1 ASNS DDX21 KCNH2 COL2A1 MAOA TCHH CYB5B HSPA13 GGH GAL NTRK3 PPT1 FGF18 FKBP4 STIP1 EIF5 ENO2 GPX3 PRKACA PRKCD STARD3 MARK2 SLC6A12 SQSTM1 PTPRD MAPK8IP2 CDK2 ONECUT1 RFC4 CA2 TACR3 AMD1 HNRNPU WIZ CCK
HALLMARK_GLYCOLYSIS http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_GLYCOLYSIS PGK1 ALDOA ENO1 TPI1 PFKP ERO1L ALDOB VEGFA MXI1 PKM2 HK2 LDHA EXT1 SLC25A10 GUSB PFKFB1 PGAM1 PYGB AK4 P4HA1 PMM2 FAM162A SDC1 EGLN3 PC B4GALT7 FBP2 IGFBP3 CHPF B3GAT3 CHST12 HS2ST1 MPI GNPDA1 AKR1A1 PPFIA4 B3GAT1 CHPF2 G6PD MDH2 CHST6 PGLS PGAM2 CHST1 GPC1 TSTA3 ALG1 GFPT1 PRPS1 GOT1 MDH1 SLC35A3 GALK1 EGFR ANGPTL4 CITED2 PLOD2 QSOX1 ME2 SPAG4 P4HA2 GAPDHS ENO2 GOT2 EXT2 SLC25A13 HMMR PDK3 CXCR4 GPC4 ECD GNE B4GALT2 FUT8 MIOX VCAN GPC3 B3GALT6 HSPA5 ME1 ADORA2B UGP2 MIF NANP ZNF292 STC2 TPST1 PGM2 GYS1 TKTL1 TGFA CHST2 PHKA2 STMN1 GALE MET LCT IRS2 POLR3K B4GALT1 EFNA3 LHX9 KDELR3 TALDO1 DPYSL4 VLDLR CD44 AGL SOX9 DDIT4 IDUA CASP6 GLCE COPB2 DSC2 HS6ST2 CDK1 PLOD1 SDC2 GMPPB PAXIP1 NSDHL RARS SLC16A3 GLRX SRD5A3 SDC3 HDLBP COL5A1 CLDN9 TFF3 STC1 KIF20A GYS2 SLC37A4 LHPP SDHC NASP AURKA B3GNT3 ISG20 LDHC ARPP19 CENPA HOMER1 BIK CYB5A HAX1 COG2 IL13RA1 NOL3 CLDN3 AGRN CLN6 TXN PAM CAPN5 PKP2 ABCB6 DCN GMPPA BPNT1 ANG GPR87 GAL3ST1 ALDH7A1 NT5E IDH1 PYGL NDUFV3 NDST3 PPP2CB PSMC4 TPBG TGFBI GALK2 CTH KIF2A CACNA1H ANKZF1 SAP30 RBCK1 ELF3 RPE B4GALT4 DEPDC1 RRAGD IER3 ALDH9A1 DLD MERTK GCLC FKBP4 SOD1 MED24 AK3 XYLT2 ARTN PPIA CHST4
HALLMARK_FATTY_ACID_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_FATTY_ACID_METABOLISM ACAA1 ACAA2 ACADL ACADM ACOT8 ACOX1 ACSL1 ALDH3A2 CCDC58 CPT2 CYP4A11 DECR1 ECH1 ECI1 ELOVL5 FABP1 FABP2 HADH HIBCH HMGCL HSD17B11 IDH1 ME1 MGLL MLYCD PCBD1 RETSAT S100A10 SUCLG1 VNN1 EHHADH ALDH9A1 HADHB ECHS1 ACADS CA2 HSD17B10 ALDH1A1 ACADVL HSD17B4 CA4 ADH1C ADH7 PTS MAOA HAO2 HSD17B7 MCEE ACAT2 AUH HPGD FH HMGCS2 ALAD GPD1 ACO2 CBR1 GRHPR ACOT2 G0S2 MDH2 HSP90AA1 BCKDHB UROS YWHAH LDHA CRYZ RDH16 INMT UGDH GSTZ1 IDH3B MDH1 CRAT ETFDH CD36 ECI2 SDHD ACSL5 HSDL2 HMGCS1 SDHC CD1D GCDH GPD2 ALDH3A1 SLC22A5 PDHB TDO2 FASN NBN PSME1 PPARA NCAPH2 BPHL ODC1 CA6 DLD HCCS EPHX1 DLST FMO1 AOC3 UROD CPT1A SETD8 UBE2L6 MIF SUCLG2 CPOX SMS CBR3 NTHL1 CIDEA IDI1 AADAT REEP6 HSPH1 APEX1 NSDHL ADIPOR2 ACSL4 ACSS1 ENO3 IDH3G LGALS1 METAP1 ALDOA ACSM3 LTC4S D2HGDH ADSL SUCLA2 SDHA XIST OSTC GLUL CYP4A22 GABARAPL1 AQP7 CYP1A1 PRDX6 ERP29 H2AFZ GAPDHS DHCR24 GAD2 PTPRG IL4I1 TP53INP2 PDHA1 RAP1GDS1 CEL BLVRA SERINC1 BMPR1B RDH11 ENO2
HALLMARK_INFLAMMATORY_RESPONSE http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INFLAMMATORY_RESPONSE CXCL10 CCL2 CCL5 FPR1 CCL20 IL1A IL8 CCL7 CCL22 CXCL11 CCR7 EDN1 CD40 CXCL9 IL6 IL1B TLR2 IL1R1 CD69 ICAM1 CCRL2 AQP9 EREG C3AR1 GNA15 CMKLR1 PTGER4 LIF IL15 NAMPT OPRK1 ITGB8 PTAFR ADM PLAUR NFKB1 INHBA OSM TNFSF10 TNFSF15 IFNGR2 EMR1 IL12B CSF1 CXCL6 TNFRSF9 LYN ACVR2A LDLR BDKRB1 HRH1 F3 BST2 PTGIR CD55 CALCRL CSF3 GPR132 IL4R NLRP3 IL15RA ADORA2B GCH1 OLR1 PTGER2 CSF3R MYC RELA TNFAIP6 IL7R IL18 GABBR1 CD82 TNFSF9 NMUR1 IL2RB TLR1 LPAR1 IRAK2 RIPK2 MMP14 P2RX7 SLC11A2 SELL P2RY2 ABCA1 FFAR2 PROK2 GNAI3 TACR1 SLC7A1 CDKN1A CYBB TIMP1 HBEGF SCARF1 EBI3 NFKBIA SRI SLC7A2 CCL17 TLR3 APLNR OSMR IL10RA PSEN1 GPR183 ATP2B1 TNFRSF1B BEST1 GPC3 SCN1B ACVR1B HPN SEMA4D KLF6 CD48 CXCR6 SLC1A2 GP1BA TAPBP RGS16 SLAMF1 LCK HIF1A AHR NMI RHOG TPBG NPFFR2 IFNAR1 ICOSLG RASGRP1 IFITM1 KCNJ2 LY6E IL18R1 IL10 KCNA3 HAS2 DCBLD2 LAMP3 VIP CD70 RGS1 SLC31A1 ADRM1 KCNMB2 SERPINE1 MXD1 AXL MEFV PVR CCL24 PDE4B LCP2 PDPN IRF7 MET ATP2A2 SLC31A2 FZD5 ITGA5 SGMS2 MARCO CD14 EIF2AK2 ROS1 ATP2C1 NDP BTG2 MSR1 PTPRE RNF144B PCDH7 SPHK1 IL18RAP RTP4 RAF1 CHST2 ITGB3 KIF1B SELE NOD2 C5AR1 EMP3 CLEC5A TACR3 SLC4A4 MEP1A SELS LTA PIK3R5 STAB1 IRF1 ICAM4 P2RX4 ABI1 CX3CL1 SLC28A2
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION COL3A1 COL5A2 COL5A1 FBN1 COL1A1 FN1 COL6A3 SERPINE1 COL1A2 COL4A1 COL4A2 VCAN IGFBP3 TGFBI SPARC LUM LAMC1 LOX LAMC2 CTGF TAGLN COL7A1 LOXL2 COL6A2 ITGAV THBS2 COL16A1 NNMT TPM1 CDH2 MMP2 COL11A1 THBS1 FAP BGN SERPINH1 FSTL1 POSTN THY1 SPP1 TNC TFPI2 NID2 ITGB5 MMP3 VIM LOXL1 FBLN5 COL12A1 ELN CDH11 COMP SPOCK1 BMP1 IL32 LAMA3 TIMP1 QSOX1 TIMP3 VCAM1 CYR61 EDIL3 CALD1 MAGEE1 FBLN1 SGCB ECM1 LAMA2 FSTL3 TPM2 INHBA DAB2 EMP3 BASP1 ITGA5 MGP VEGFA CXCL1 WNT5A SDC1 PLOD2 PCOLCE GREM1 ITGB1 COL5A3 RHOB HTRA1 FGF2 SNTB1 GADD45A MEST LRRC15 TNFRSF11B CD59 ACTA2 EFEMP2 MATN2 PCOLCE2 SERPINE2 GPC1 ABI3BP FUCA1 SLIT3 LAMA1 PMEPA1 COL8A2 FBN2 IGFBP2 PFN2 SDC4 CD44 GADD45B IL8 GLIPR1 ANPEP LEPRE1 VEGFC MMP14 SGCD PLOD1 MATN3 MYL9 SLC6A8 CALU PRRX1 TNFRSF12A FMOD ID2 GEM PLAUR MYLK TGFB1 SFRP1 PLOD3 IL6 APLP1 FBLN2 MSX1 PTX3 FZD8 JUN FERMT2 DKK1 SNAI2 DST TPM4 DCN GJA1 PMP22 IGFBP4 COPA LRP1 ITGA2 FLNA MFAP5 PTHLH TGFBR3 SFRP4 LGALS1 RGS4 CDH6 SAT1 NT5E DPYSL3 PPIB TGM2 SGCG ITGB3 PDLIM4 CTHRC1 ECM2 CRLF1 AREG IL15 MCM7 GAS1 PRSS2 CADM1 OXTR SCG2 CXCL6 MMP1 TNFAIP3 CAPG CAP2 MXRA5 FOXC2 NTM ENO2 FAS BDNF ADAM12 PVR CXCL12 PDGFRB SLIT2 NOTCH2 GLT25D1 GPX7 WIPF1
HALLMARK_COMPLEMENT http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_COMPLEMENT C2 C1S CFB C1R SERPINE1 MMP14 SERPING1 CTSL1 F5 MMP13 F7 CTSS LGMN PLG C1QA CASP1 GZMA ADAM9 CALM3 C1QC TIMP1 DPP4 KLK1 KLKB1 CD59 CR2 MMP15 LAP3 SPOCK2 F10 CTSB SERPINA1 CTSO CD40LG CBLB PDP1 C4BPB PLEK GP9 PLAUR C3 F2 CASP4 STX4 CTSC USP15 CR1 DUSP6 SERPINB2 GPD2 CFH FN1 CD36 CA2 PSMB9 APOBEC3G FCN1 GZMK PDGFB CLU CASP10 LRP1 CTSD S100A9 WAS BRPF3 PLAT CDA MT3 CASP7 PRSS36 PFN1 GZMB RNF4 ZEB1 CASP5 IRF1 PGCP CDK5R1 ATOX1 PIK3CA TMPRSS6 CPM RCE1 CALM1 DOCK9 KYNU RASGRP1 USP14 LCP2 GP1BA KIF2A GNB4 LCK OLR1 PREP SEPX1 LTA4H ZFPM2 LYN ACTN2 SIRT6 APOC1 PRKCD ITGAM DGKH LTF MAFF KCNIP2 PCLO DOCK10 SH2B3 RABIF SRC HPCAL4 CD46 PRDM4 GNAI3 C9 PPP2CB IRF2 FYN JAK2 PLA2G4A PRCP USP8 RHOG L3MBTL4 LAMP2 PIM1 CXCL1 F3 GNAI2 CASP9 XPNPEP1 PLSCR1 IRF7 CD55 HSPA5 GNB2 DYRK2 PLA2G7 S100A12 GRB2 PHEX GNGT2 DOCK4 MMP12 KCNIP3 FDX1 TIMP2 MMP8 FCER1G ZFYVE20 ANXA5 CTSL2 GCA EHD1 PRSS3 COL4A2 CSRP1 PIK3R5 SERPINC1 ANG APOBEC3F GATA3 DUSP5 CASP3 USP16 CP PSEN1 LIPA PCSK9 DGKG GNG2 ME1 GMFB SCG3 PPP4C CCL5 CTSH F8 APOA4 IL6 AKAP10 ERAP2 VCPIP1 HSPA1A RAF1 NOTCH4 ADRA2B CEBPB HNF4A LGALS3 TNFAIP3 CDH13 ITIH1 TFPI2 PIK3CG S100A13
HALLMARK_APICAL_SURFACE http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_APICAL_SURFACE B4GALT1 RHCG MAL LYPD3 PKHD1 ATP6V0A4 AIM1 SHROOM2 SRPX MDGA1 TMEM8B THY1 PCSK9 EPHB4 DCBLD2 GHRL LYN GAS1 FLOT2 PLAUR AKAP7 ATP8B1 EFNA5 SLC34A3 APP GSTM3 HSPB1 SLC2A4 IL2RB RTN4RL1 NCOA6 SULF2 ADAM10 BRCA1 GATA3 AFAP1L2 IL2RG CD160 ADIPOR2 SLC22A12 NTNG1 SCUBE1 CX3CL1 CROCC
HALLMARK_APICAL_JUNCTION http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_APICAL_JUNCTION ACTN1 CLDN7 ACTN3 CLDN19 DLG1 TJP1 COL17A1 PVRL1 CLDN9 CDH3 CTNND1 CDH1 LIMA1 VCL SHROOM2 PVRL3 PVRL2 CLDN14 PTPRC THY1 VASP ITGB1 ZYX ACTN4 CLDN4 CADM3 ITGA3 NF2 B4GALT1 NEXN CDH6 ADAM15 PTK2 HADH LAMB3 CLDN11 CDH4 IRS1 SORBS3 CLDN8 EVL CLDN15 THBS3 PVRL4 JAM3 CDH11 ITGB4 RASA1 AKT2 TMEM8B LAMA3 RSU1 ICAM1 CLDN18 GTF2F1 TSC1 LAMC2 NRAP CTNNA1 CD99 FSCN1 COL16A1 GNAI2 TGFBI MPP5 JUP ACTN2 INSIG1 LAYN PFN1 CNN2 TAOK2 AMIGO2 MDK INPPL1 CLDN6 ARPC2 SRC PBX2 MAPK14 MAP4K2 PTEN CALB2 CNTN1 TSPAN4 VCAN CDH8 ATP1A3 EPB41L2 MYL9 SPEG ADRA1B SYK CADM2 ALOX15B CX3CL1 MYH10 DMP1 CDSN MAPK13 MYL12B RAC2 FBN1 DSC1 CD34 ICAM4 MSN MAPK11 ACTC1 TRAF1 CRB3 ITGA2 ITGA10 BAIAP2 ARHGEF6 ACTG1 MVD PDZD3 ADAM9 PCDH1 SLIT2 KRT31 SGCE GNAI1 PIK3CB NLGN2 YWHAH PARVA CRAT ADAMTS5 AMH EGFR ICAM2 CD274 CDH15 SHC1 MPZL2 WNK4 NFASC PIK3R3 SDC3 SIRPA GRB7 FLNC PARD6G COL9A1 NRXN2 ZAK SLC30A3 RHOF BMP1 MMP2 ICAM5 VWF MYH9 CD209 VCAM1 DHX16 ACTG2 NEGR1 NF1 ADAM23 PLCG1 KCNH2 CERCAM NRTN IKBKG DSC3 ACTB TUBG1 PPP2R2C HRAS MMP9 TNFRSF11B PKD1 CDK8 FYB AMIGO1 CD276 GAMT NLGN3 SKAP2 RRAS CAP1 EXOC4 ACTA1 TIAL1 LDLRAP1 VAV2 AKT3 SYMPK STX4 PECAM1 MADCAM1 ITGA9 CD86 TRO CLDN5 MPZL1 WASL
HALLMARK_INTERFERON_GAMMA_RESPONSE http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_GAMMA_RESPONSE STAT1 ISG15 IFIT1 MX1 IFIT3 IFI35 IRF7 IFIT2 OAS2 TAP1 EIF2AK2 RSAD2 MX2 IRF1 OAS3 TNFSF10 IRF9 CXCL10 IFI44 BST2 XAF1 SP110 OASL PSMB8 IFI44L IFITM3 DDX60 LGALS3BP GBP4 IRF8 PSMB9 PML IFIH1 UBE2L6 IFI27 ADAR LY6E STAT2 CXCL9 IL10RA PLA2G4A TRIM21 USP18 PTGS2 EPSTI1 C1S DDX58 IL15 NLRC5 NMI IDO1 PSMB10 CXCL11 ITGB7 SAMHD1 HERC6 CMPK2 SAMD9L RTP4 PTPN2 PARP14 TNFAIP2 IFITM2 PLSCR1 SOCS1 CASP1 ICAM1 WARS PSME1 ISG20 IRF2 TRIM14 FCGR1A MARCH1 SOCS3 JAK2 HLA-DMA PARP12 TNFAIP6 TRIM26 VCAM1 CD274 CIITA NAMPT SELP GPR18 FPR1 PRIC285 PSME2 SERPING1 CCL5 RNF31 SOD2 TRIM25 LAP3 PSMA3 RNF213 PELI1 CFB CD86 TXNIP HLA-DQA1 GCH1 PNP CCL7 PTPN6 SPPL2A IL4R PNPT1 DHX58 BTG1 CASP8 IFI30 CCL2 FGL2 CASP7 SECTM1 IL15RA CD40 TRAFD1 HLA-DRB1 GBP6 LCP2 HLA-G MT2A RIPK1 KLRK1 UPP1 PSMB2 TDRD7 HIF1A EIF4E3 VAMP8 PFKP CD38 ZBP1 BANK1 TOR1B RBCK1 PDE4B MVP IL7 BPGM FTSJD2 AUTS2 B2M RIPK2 CD69 MYD88 PSMA2 PIM1 NOD1 CFH TAPBP SLC25A28 PTPN1 TNFAIP3 SSPN NUP93 MTHFD2 CDKN1A IRF4 NFKB1 BATF2 HLA-B LATS2 IRF5 SLAMF7 ISOC1 P2RY14 STAT3 NCOA3 HLA-A IL6 GZMA IFNAR2 CD74 RAPGEF6 CASP4 FAS OGFR ARL4A SRI LYSMD2 CSF2RB ST3GAL5 C1R CASP3 CMKLR1 NFKBIA METTL7B ST8SIA4 XCL1 IL2RB VAMP5 IL18BP ZNFX1 ARID5B APOL6 STAT4
HALLMARK_INTERFERON_ALPHA_RESPONSE http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_ALPHA_RESPONSE MX1 ISG15 OAS1 IFIT3 IFI44 IFI35 IRF7 RSAD2 IFI44L IFITM1 IFI27 IRF9 OASL EIF2AK2 IFIT2 CXCL10 TAP1 SP110 DDX60 UBE2L6 USP18 PSMB8 IFIH1 BST2 LGALS3BP ADAR ISG20 GBP2 IRF1 PLSCR1 PSMB9 HERC6 SAMD9 CMPK2 IFITM3 RTP4 STAT2 SAMD9L LY6E IFITM2 PRIC285 CXCL11 TRIM21 PARP14 TRIM26 PARP12 NMI RNF31 HLA-C CASP1 TRIM14 TDRD7 DHX58 PARP9 PNPT1 TRIM25 PSME1 WARS EPSTI1 UBA7 PSME2 B2M TRIM5 C1S LAP3 LAMP3 GBP4 NCOA7 TMEM140 CD74 GMPR PSMA3 PROCR IL7 IFI30 IRF2 CSF1 IL15 CNP FAM46A IL4R FTSJD2 CD47 LPAR6 MOV10 CASP8 TXNIP SLC25A28 SELL TRAFD1 BATF2 RIPK2 CCRL2 NUB1 OGFR FAM125A ELF1
HALLMARK_PROTEIN_SECRETION http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_PROTEIN_SECRETION ARCN1 TMED10 COPB2 RAB14 ATP7A COPB1 LAMP2 EGFR IGF2R COPE PPT1 AP3S1 BET1 CLCN3 AP2S1 CLTC AP2M1 RER1 KIF1B ARF1 OCRL ICA1 MON2 ARFGEF2 TMED2 NAPG TMX1 PAM SCAMP1 SH3GL2 RAB2A COG2 VAMP3 ERGIC3 DOPEY1 VAMP4 VPS4B NAPA GNAS STX7 SEC22B VPS45 STX16 YKT6 SNX2 ARFGEF1 CLTA CLN5 M6PR SGMS1 USO1 TSG101 DNM1L LMAN1 YIPF6 ARFIP1 ANP32E TSPAN8 DST SCRN1 SEC31A VAMP7 SCAMP3 AP2B1 RAB22A AP3B1 TPD52 ATP6V1H GBF1 KRT18 CAV2 ATP1A1 BNIP3 ZW10 GALC ADAM10 RAB5A GOLGA4 SEC24D AP1G1 MAPK1 GOSR2 RPS6KA3 STAM ABCA1 SNAP23 SOD1 GLA ATP6V1B1 STX12 CD63 TOM1L1 SSPN ARFGAP3 RAB9A CTSC
HALLMARK_MYOGENESIS http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MYOGENESIS ACTA1 TNNI2 MYL1 TNNC1 TNNC2 MYH3 MYLPF TNNT3 TNNT2 CASQ2 ACTC1 MYOM1 MYL4 MYBPH MYH7 MYH8 ACTN2 TNNI1 CRYAB SGCG HRC TNNT1 DES MYOZ1 RYR1 CSRP3 ADAM12 ATP2A1 CKM SVIL MYOM2 MYL6B TPM2 MYL2 CKMT2 BIN1 MYH1 ENO3 FLII FXYD1 TPM3 DMD IGFBP3 CHRNB1 SPEG FHL1 ACTN3 TCAP MYLK MYL3 PYGM LDB3 COX6A2 FABP3 MYL7 ITGB5 CHRNA1 SSPN COL3A1 KCNH1 GJA5 MYF6 MYH2 MAPK12 PGAM2 MYOG MYH4 AEBP1 HBEGF MEF2C NOS1 CNN3 IGFBP7 CACNA1H GSN CACNG1 PPFIA4 MB SPHK1 SCHIP1 MEF2D SMTN CDKN1A GAA TPD52L1 HSPB2 SGCA BDKRB2 COX7A1 COL4A2 PLXNB2 CTF1 COL15A1 KCNH2 AGRN MYO1C SIRT2 SGCD SORBS1 VIPR1 FGF2 FKBP1B TEAD4 CASQ1 KLF5 PDLIM7 AK1 TAGLN RIT1 MEF2A ANKRD2 AKT2 LAMA2 ST5 IFRD1 NCAM1 SYNGR2 PICK1 COL6A3 CRAT DMPK MYH11 MYH9 IGF1 CKB FST GPX3 PVALB PTP4A3 ITGB1 HSPB8 ACHE CHRNG PKIA NAV2 HDAC5 ATP6AP1 CLU ACSL1 COL1A1 MRAS PDE4DIP AGL ERBB3 GABARAPL2 CAV3 BHLHE40 PPP1R3C LARGE LPIN1 CDH13 NQO1 PRNP PSEN2 DAPK2 LSP1 SLC6A8 REEP1 EIF4A2 SH2B1 MYBPC3 ITGA7 SPTAN1 SORBS3 PC SCD GNAO1 STC2 CFD RB1 BAG1 ABLIM1 PTGIS MAPRE3 OCEL1 SH3BGR NOTCH1 TSC2 TGFB1 FDPS CAMK2B EPHB3 GADD45B APP APLNR ITGB4 SOD3 FOXO4 EFS PFKM COL6A2 DTNA KIFC3 SPARC SPDEF SLN WWTR1 CD36 ADCY9 APOD
HALLMARK_ANDROGEN_RESPONSE http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ANDROGEN_RESPONSE KLK3 KLK2 ACSL3 PIAS1 CAMKK2 NKX3-1 TMPRSS2 APPBP2 CENPN BMPR1B MAF FADS1 ZBTB10 HMGCR SPCS3 INSIG1 NGLY1 UBE2J1 ELK4 ABCC4 ELOVL5 ALDH1A3 TARP AZGP1 ABHD2 SAT1 DBI DHCR24 SORD STK39 TPD52 IDI1 B2M MAP7 DNAJB9 FKBP5 HERC3 PGM3 HOMER2 ELL2 UAP1 SEC24D LMAN1 PMEPA1 INPP4B RRP12 SEPP1 NDRG1 KRT19 ITGAV B4GALT1 MAK SPDEF GSR KRT8 LIFR PPAP2A STEAP4 GUCY1A3 SRP19 CCND3 IQGAP2 RAB4A SLC26A2 SMS ZMIZ1 SGK1 MERTK HPGD ANKH GNAI3 SRF SLC38A2 HMGCS1 ARID5B CDC14B TNFAIP8 XRCC5 GPD1L ACTN1 RPS6KA3 TSC22D1 PDLIM5 TMEM50A ADAMTS1 NCOA4 AKAP12 SCD PTK2B CDK6 ADRM1 H1F0 HSD17B14 VAPA CCND1 XRCC6 MYL12A UBE2I PTPN21 AKT1 PA2G4
HALLMARK_ESTROGEN_RESPONSE_LATE http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ESTROGEN_RESPONSE_LATE TFF1 SLC9A3R1 TPD52L1 PRSS23 CA12 PDZK1 ANXA9 CELSR2 TJP3 PGR RET MYB TPBG EGR3 ARL3 OLFM1 NPY1R SCNN1A XBP1 AREG IL17RB NRIP1 ASS1 TFF3 FKBP4 SLC27A2 SEMA3B GPER LLGL2 AGR2 KRT19 WISP2 BLVRB FLNB PDCD4 CALCR IGFBP4 DNAJC12 TIAM1 TSPAN13 CXCL12 RAB31 PKP3 CYP26B1 FKBP5 SIAH2 ISG20 TMPRSS3 SERPINA3 WFS1 MAPT PDLIM3 RBBP8 GJB3 PRLR SLC1A4 FOS PLA2G16 SLC7A5 SERPINA5 IMPA2 DHCR7 MYOF CDH1 EMP2 OVOL2 DLG5 SOX3 CHPT1 KLK10 ELOVL5 RAPGEFL1 JAK2 SLC26A2 SLC22A5 ITPK1 PCP4 PAPSS2 NAB2 FAM102A BCL2 LSR CACNA2D2 CA2 ASCL1 ACOX2 CISH GLA PTGES PERP OPN3 KRT13 HSPB8 UGDH CLIC3 KLK11 PLAC1 ABHD2 SCARB1 DCXR CCND1 SFN ABCA3 SULT2B1 CCNA1 STIL MICB ZFP36 CAV1 NBL1 CD44 HR HOMER2 BTG3 GAL ETFB BAG1 FRK SLC16A1 AFF1 TFAP2C IGSF1 HPRT1 CDC6 FARP1 AMFR DHRS2 NXT1 S100A9 SLC29A1 SLC24A3 FOXC1 KIF20A TOB1 FDFT1 DNAJC1 TPSAB1 TSTA3 FGFR3 SGK1 ID2 GALE BATF MAPK13 FABP5 MEST JAK1 CYP4F11 KCNK5 CPE XRCC3 CXCL14 SCUBE2 CDC20 IL6ST GINS2 TRIM29 UNC13B LAMC2 LARGE SLC2A8 PLXNB1 PRKAR2B RPS6KA2 HSPA4L TFPI2 SERPINA1 TNNC1 HMGCS2 ALDH3A2 CD9 IDH2 SORD MDK ALDH3B1 PTGER3 RABEP1 KLF4 PPIF SNX10 METTL3 PLK4 COX6C ST14 NCOR2 MOCS2 NMU TH RNASEH2A CHST8 TST TOP2A CKB LTF DUSP2 PTPN6 ATP2B4 ST6GALNAC2 ADD3 DYNLT3
HALLMARK_ESTROGEN_RESPONSE_EARLY http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ESTROGEN_RESPONSE_EARLY GREB1 CA12 SLC9A3R1 MYB ANXA9 IGFBP4 SYBU NPY1R PDZK1 NRIP1 MLPH HSPB8 EGR3 KRT19 LRIG1 KDM4B PGR RHOBTB3 TPD52L1 ELOVL2 RET TPBG TFF1 MAPT SCNN1A ABAT FLNB XBP1 CELSR2 RAB31 MYBL1 MREG FAM102A MSMB STC2 FAM134B SIAH2 ZNF185 SLC19A2 SLC1A4 FHL2 BCL2 PMAIP1 AREG OVOL2 TSKU ADCY9 RASGRP1 MUC1 KAZN SLC27A2 FKBP4 CXCL12 TMPRSS3 RARA IL17RB CBFA2T3 TFF3 UGCG CCND1 SLC22A5 WFS1 PTGES WWC1 WISP2 MYC ITPK1 TMEM164 ARL3 MED13L SEMA3B KRT18 SLC16A1 TJP3 SLC26A2 FAIM3 SULT2B1 SNX24 TFAP2C TTC39A GJA1 PRSS23 OLFM1 RAPGEFL1 ASB13 TIPARP ABCA3 FRK DHRS2 AQP3 KCNK15 TGIF2 FOXC1 ELF3 REEP1 PEX11A PODXL KLF4 BAG1 CELSR1 PLA2G16 SLC7A5 MPPED2 TIAM1 CLDN7 MYOF RBBP8 OLFML3 GFRA1 FARP1 SVIL TGM2 DEPTOR CYP26B1 PAPSS2 SLC1A1 DLC1 JAK2 AFF1 KLK10 P2RY2 BLVRB CISH GLA ADD3 PDLIM3 FAM63A FOS KRT8 SLC37A1 B4GALT1 CALCR ESRP2 IGF1R NBL1 SFN OPN3 ABHD2 AR SLC39A6 SYT12 CD44 MED24 BCL11B CANT1 KRT13 KRT15 TOB1 SLC7A2 LAD1 TUBB2B TBC1D30 SEC14L2 ENDOD1 HR SCARB1 NCOR2 RHOD INPP5F PPIF DHRS3 FDFT1 GAB2 UNC119 KLF10 HES1 FKBP5 SLC2A1 AMFR NADSYN1 INHBB BHLHE40 CALB2 FASN CHPT1 MYBBP1A ELOVL5 DYNLT3 ABLIM1 SOX3 SLC24A3 RAB17 MAST4 KCNK5 ELF1 RPS6KA2 ISG20L2 IL6ST SYNGR1 SH3BP5 ALDH3B1 THSD4 CLIC3 NXT1 NAV2 RRP12 ADCY1 DHCR7 MICB AKAP1
HALLMARK_ADIPOGENESIS http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ADIPOGENESIS FABP4 ADIPOQ PPARG LIPE DGAT1 LPL CPT2 CD36 GPAM ADIPOR2 ACAA2 ETFB ACOX1 ACADM HADH IDH1 SORBS1 ACADS UCK1 SCP2 DECR1 CDKN2C TALDO1 TST MCCC1 PGM1 REEP5 BCL2L13 SLC25A10 ME1 PHYH PIM3 YWHAG NDUFAB1 GPD2 ADIG ECHS1 QDPR CS ECH1 SLC25A1 ACADL TOB1 GRPEL1 CRAT GBE1 SDPR SCARB1 PEMT CHCHD10 AK2 APOE UQCR10 TANK ANGPTL4 ACO2 FAH ACLY IFNGR1 SLC5A6 JAGN1 EPHX2 IDH3G GPX3 ELMOD3 ORM1 RETSAT ESRRA HIBCH SUCLG1 STAT5A ITGA7 MRAP PLIN2 CYC1 ALDH2 RNF11 ALDOA SULT1A1 DDT SDHB CD151 SLC27A1 BCKDHA C3 LEP ADCY6 ELOVL6 LTC4S SPARCL1 FAM82A2 MTCH2 ANKRD57 SLC1A5 CMPK1 REEP6 NDUFA5 FZD4 DRAM2 MGST3 ATP1B3 RETN STOM ESYT1 GHITM DNAJC15 GADD45A VEGFB PFKL COQ3 OBFC2A CYP4B1 PPM1B ARAF PTRF COL4A1 IMMT DHRS7 COL15A1 NMT1 COQ5 LAMA4 AGPAT3 BAZ2A IDH3A LIFR PREB PTGER3 GPHN PFKFB3 GPX4 SSPN SQRDL MOSC2 DLD ITIH5 CD302 ATL2 AGPAT6 LPCAT3 TKT UQCRC1 CAT OMD DLAT MRPL15 RIOK3 RTN3 CHUK G3BP2 SDHC SAMM50 ARL4A SNCG PDCD4 COQ9 APLP2 SOD1 PTCD3 PHLDB1 ENPP2 HSPB8 AIFM1 CCNG2 PPP1R15B MDH2 ABCA1 COX7B MYLK COX8A DHRS7B FAM73B MGLL ITSN1 DHCR7 RREB1 CMBL UBC ATP5O PRDX3 DBT NDUFS3 NKIRAS1 RAB34 CIDEA UQCRQ PEX14 BCL6 COX6A1 DNAJB9 MAP4K3 ANGPT1 UBQLN1 NDUFB7 SLC19A1 ABCB8 PQLC3 POR UCP2 UQCR11
HALLMARK_IL6_JAK_STAT3_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_IL6_JAK_STAT3_SIGNALING IL4R IL6ST STAT1 IL1R1 CSF2RB SOCS3 STAT3 OSMR IL2RG IFNGR1 TYK2 IL13RA1 TLR2 IFNGR2 IL10RB IL6 IL1R2 IL3RA IFNAR1 TNFRSF1A MYD88 ACVR1B CSF3R ITGB3 REG1A CXCL1 A2M CSF2RA IL15RA IRF9 PDGFC HAX1 BAK1 EBI3 INHBE CRLF2 TNFRSF1B CD14 PTPN1 PTPN2 IL1B CSF1 IL18R1 TNF PF4 CXCL13 LTBR FAS IL17RA CXCL10 IL9R STAM2 TNFRSF12A STAT2 HMOX1 LEPR CBL CD9 CXCL3 TGFB1 MAP3K8 ITGA4 CD38 JUN SOCS1 ACVRL1 PIM1 TNFRSF21 PIK3R5 GRB2 IRF1 DNTT CSF2 IL2RA PTPN11 IL12RB1 CCR1 CNTFR PLA2G2A CXCL9 CD44 IL7 CXCL11 CCL7 LTB IL17RB CD36
HALLMARK_MITOTIC_SPINDLE http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MITOTIC_SPINDLE ARHGEF2 CLASP1 KIF11 KIF23 ALS2 ARF6 MYO9B MYH9 TUBGCP3 CKAP5 RACGAP1 PREX1 ARHGEF3 NUMA1 SPTBN1 KIF2C KIF5B TTK APC CEP250 PAFAH1B1 CDC42EP2 KIF3B CCDC88A KIF15 BIRC5 CNTROB NF1 TSC1 CDC27 CNTRL TUBGCP5 KIF4A MAPRE1 FGD6 BRCA2 PLK1 RASA1 NEK2 WASF1 TOP2A TRIO ARHGEF11 KATNB1 PRC1 ANLN CDK5RAP2 SMC3 TUBGCP2 ESPL1 MAP1S ARHGAP27 DOCK4 SAC3D1 INCENP ARHGAP5 GSN NET1 LRPPRC RABGAP1 FLNB ARAP3 FGD4 ABR CENPJ NCK1 CENPF KIF20B WASF2 MYH10 CENPE CYTH2 MID1 KLC1 MARK4 ARL8A CEP57 UXT ARHGAP4 CDC42EP4 SASS6 LATS1 OPHN1 WASL MAP3K11 SOS1 ABL1 TIAM1 KIF1B ITSN1 SHROOM1 NCK2 DLGAP5 BCR RANBP9 EPB41L2 SEPT9 KATNA1 TUBD1 TPX2 KIF3C SHROOM2 TUBGCP6 SPTAN1 PALLD ARFIP2 KNTC1 HOOK3 SUN2 MID1IP1 DLG1 FLNA ARHGAP10 CDC42BPA ARHGEF12 MARCKS NIN PCM1 RALBP1 EZR SSH2 CDK1 RAB3GAP1 FARP1 SYNPO RHOF ECT2 EPB41 RAPGEF6 KIF22 PCGF5 STAU1 ARHGDIA AURKA FBXO5 NUSAP1 PXN BCAR1 CD2AP AKAP13 HDAC6 AZI1 LLGL1 ATG4B PCNT ALMS1 CRIPAK KPTN DST KIFAP3 PPP4R2 ARHGAP29 RASAL2 CCNB2 PIF1 RASA2 NEDD9 SMC1A ACTN4 PKD2 CLIP2 CDC42 NDC80 TLK1 TAOK2 TBCD CAPZB DOCK2 CTTN SMC4 ARFGEF1 TUBA4A LMNB1 ABI1 ROCK1 CEP192 BUB1 GEMIN4 PLEKHG2 RICTOR BCL2L11 DYNC1H1 FSCN1 ARHGEF7 DYNLL2 MYO1E BIN1 NOTCH2 RFC1 PDLIM5 RHOT2 SORBS2 CDC42EP1 VCL CLIP1 STK38L YWHAE RAPGEF5 CEP72 CSNK1D
HALLMARK_CHOLESTEROL_HOMEOSTASIS http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_CHOLESTEROL_HOMEOSTASIS FDPS CYP51A1 IDI1 FDFT1 DHCR7 SQLE HMGCS1 NSDHL LSS MVD LDLR TM7SF2 ALDOC EBP SCD PMVK MVK LPL SC5DL FADS2 HMGCR HSD17B7 ANXA13 SREBF2 PCYT2 ACSS2 ATF3 ADH4 ETHE1 ECH1 CBS GUSB FASN LGALS3 ATF5 ANXA5 TP53INP1 CHKA GSTM2 ACAT2 AVPR1A PLSCR1 CLU ERRFI1 TRIB3 CXCL16 TNFRSF12A ACTG1 JAG1 LGMN FBXO6 GPX8 PNRC1 ANTXR2 MAL2 CD9 PPARG GLDC STX5 STARD4 CTNNB1 TMEM97 FAM129A PDK3 PLAUR SEMA3B GNAI1 ABCA2 ATXN2 NFIL3 ALCAM FABP5 S100A11 CPEB2
HALLMARK_ANGIOGENESIS http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ANGIOGENESIS VCAN POSTN FSTL1 LRPAP1 STC1 LPL VEGFA PF4 THBD FGFR1 TNFRSF21 CCND2 COL5A2 ITGAV SERPINA5 KCNJ8 APP JAG1 COL3A1 SPP1 NRP1 OLR1 PDGFA PTK2 SLCO2A1 PGLYRP1 VAV2 S100A4 MSX1 VTN TIMP1 APOH PRG2 JAG2 LUM CXCL6
HALLMARK_XENOBIOTIC_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_XENOBIOTIC_METABOLISM CYP1A1 FAH DCXR CYP1A2 GSTA3 CYP2J2 CYP27A1 ADH1C UGDH ASL NQO1 ALAS1 GSTM4 CYP2C18 PTS CYB5A ACOX2 EPHX1 LCAT SLC35D1 GSS FMO3 IDH1 AKR1C3 SLC22A1 GSTO1 ARG1 CDO1 FMO1 ALDH9A1 POR NDRG2 UPB1 ECH1 PTGES PDK4 AHCY COMT AOX1 CFB DDAH2 HGFAC F11 CYP26A1 MCCC2 SERPINA6 GNMT BLVRB HACL1 MAOA KYNU DHPS SERPINE1 SLC6A12 GCH1 DHRS7 PAPSS2 ALDH2 HSD11B1 SLC35B1 KARS CA2 LPIN2 CAT CYP2S1 RAP1GAP FBP1 RBP4 GCKR CDA MTHFD1 ADH7 DHRS1 VNN1 CNDP2 SLC6A6 FETUB CROT GAD1 AKR1C2 DAK IGF1 SSR3 GABARAPL1 TMBIM6 CD36 CES1 SHMT2 TMEM176B GSTT2 PLG HMOX1 SPINT2 ALDH3A1 GSR ABHD6 XDH PPARD ELOVL5 CYP4F2 RETSAT CYFIP2 PINK1 GCLC ESR1 PMM1 TDO2 MT2A ATP2A2 DDT FABP1 ACP2 ABCD2 G6PC DDC ACOX3 SAR1B FBLN1 ADH5 CRP ABCC2 ETS2 NPC1 CASP6 BPHL IL1R1 ENTPD5 TNFRSF1A IGFBP4 PYCR1 CSAD VTN ID2 ETFDH HRG TYR UPP1 BCAR1 CBR1 APOE SLC12A4 TMEM97 SLC46A3 PTGDS MPP2 PTGR1 AQP9 EPHA2 PSMB10 FAS ACOX1 GART HPRT1 PGD ABCC3 SMOX TTPA HES6 GCNT2 MAN1A1 IGFBP1 ITIH4 PROS1 TPST1 LEAP2 NFS1 PGRMC1 CYP17A1 ARPP19 SERTAD1 ARG2 HNF4A REG1A CCL25 PEMT ACO2 LONP1 NMT1 PTGES3 F10 TAT MARCH6 JUP ACP1 MBL2 TGFB2 ENPEP HSD17B2 ANGPTL3 PC PDLIM5 CYP2E1 BCAT1 ATOH8 SLC1A5 IRF8 NINJ1 AP4B1 ACSM1 ITIH1
HALLMARK_KRAS_SIGNALING_DN http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_KRAS_SIGNALING_DN CDH16 SPTBN2 FGFR3 NOS1 PDE6B SIDT1 NTF3 SCN10A TAS2R4 DTNB HTR1D MAST3 SLC6A3 CLDN8 TGM1 PCDHB1 THRB YPEL1 RYR2 GDNF CAMK1D AMBN LFNG SERPINA10 ALOX12B CALCB FGGY SPRR3 ATP6V1B1 EDN1 UPK3B GAMT PRODH RYR1 GPR19 SLC29A3 EDN2 GPRC5C C5 FAM164C EDAR KCNMB1 FAM46C STAG3 KRT4 SLC25A23 INSL5 GP1BA MLL2 ABCG4 MYH7 BRDT PTGFR KCNN1 SEPP1 IFI44L PROP1 LGALS7 BMPR1B PDK2 DCC SNCB COL2A1 UGT2B17 PPYR1 DLK2 WNT16 SLC6A14 ITGB1BP2 SLC12A3 YBX2 CKM CPB1 MAGIX ARHGDIG CALML5 KRT1 MTHFR ABCB11 MYOT CELSR2 KLK7 THNSL2 CHRNG NR4A2 CD40LG KRT13 GP2 CD207 CCR8 ZBTB16 PARK2 CPA2 MEFV CCNA1 SLC38A3 KLK8 CYP39A1 KCNQ2 SLC30A3 CHST2 ITIH3 EGF MSH5 TEX15 CLPS ENTPD7 CLSTN3 CYP11B2 CLDN16 HSD11B2 ADCK3 HNF1A FGF22 TFCP2L1 OXT KCND1 H2AFY2 NRIP2 RGS11 CPEB3 TG PTPRJ NUDT11 FSHB IDUA TNNI3 GTF3C5 TFF2 SSTR4 COPZ2 PDCD1 SLC16A7 KCNE2 MFSD6 KLHDC8A CNTFR IL5 NPHS1 SCGB1A1 CCDC106 PAX3 VPREB1 TSHB CACNA1F AKR1B10 P2RX6 KRT15 PAX4 BTG2 GPR3 GRID2 TCL1A PLAG1 PKP1 IRS4 IL12B EPHA5 SOX10 SNN CACNG1 SPHK2 IGFBP2 CAPN9 TCF7L1 TGFB2 SMPX LYPD3 PNMT SYNPO MX1 IFNG NR6A1 ACTC1 RSAD2 ADRA2C BARD1 HTR1B FGF16 ODZ2 CDKAL1 SHOX2 SGK1 RIBC2 SKIL NGB ASB7 MYO15A SLC5A5 KRT5 ZFP112 TFAP2B CCDC132 CD80 ATP4A ARPP21 SERPINB2 TLX1 EFHD1 P2RY4
HALLMARK_KRAS_SIGNALING_UP http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_KRAS_SIGNALING_UP ANGPTL4 ITGA2 SPRY2 HBEGF RBP4 HSD11B1 ETV4 GLRX DUSP6 SCG5 ETV5 ITGB2 AKT2 PPBP G0S2 GABRA3 IRF8 BIRC3 FGF9 DCBLD2 INHBA TFPI TSPAN1 ADAM8 SLPI PRKG2 MMP11 MMP10 TMEM158 TNFAIP3 PRDM1 GALNT3 ETS1 MMP9 WNT7A IGFBP3 SPP1 ETV1 CLEC4A CCND2 TSPAN7 ITGBL1 EMP1 CDADC1 KIF5C TRIB2 SDCCAG8 PCP4 CFHR2 ALDH1A2 NR0B2 ALDH1A3 AMMECR1 SATB1 GUCY1A3 CSF2 APOD TOR1AIP2 CMKLR1 TMEM176B GPR124 LAPTM5 CD37 CAB39L CIDEA ZNF639 IL1B GYPC LY96 FLT4 SPON1 BMP2 PLEK2 IGF2 NR1H4 SNAP25 ACE PRRX1 C3AR1 TRAF1 TLR8 ID2 TMEM100 PLAUR GADD45G CBX8 SCN1B PTBP2 NAP1L2 AKAP12 PLAT SCG3 ANO1 IL1RL2 CXCL10 ATG10 YRDC HDAC9 PEG3 SEMA3B TNNT2 LIF CFB BTC PPP1R15A PTPRR CCL20 ARG1 RETN KLF4 MMD PDCD1LG2 HIST1H2BB HOXD11 TRIB1 F2RL1 ANXA10 TSPAN13 MTMR10 CFH LAT2 ERO1L RELN KCNN4 TMEM176A MAP4K1 PTGS2 IL33 MAFB LCP1 NGF CA2 SERPINA3 RGS16 CTSS USP12 CPE SPARCL1 ABCB1 USH1C CSF2RA BTBD3 IL2RG DNMBP IL10RA EREG SLMO2 EPHB2 FBXO4 CROT MPZL2 ANKH CBR4 DOCK2 GPRC5B RABGAP1L MALL STRN ST6GAL1 PIGR VWA5A PSMB8 F13A1 NRP1 SOX9 JUP ELTD1 ZNF277 EPB41L3 PCSK1N FUCA1 PLVAP ADAM17 AVL9 ADAMDEC1 HKDC1 MAP7 IL7R RBM4 BPGM ENG GFPT2 PLAU GNG11 PTCD2 MAP3K1 CBL CXCR4 NIN IKZF1 WDR33 MYCN FCER1G PECAM1 FAM190B SNAP91 EVI5 TNFRSF1B GPNMB TPH1
HALLMARK_P53_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_P53_PATHWAY CDKN1A BTG2 MDM2 CCNG1 FAS TOB1 GADD45A PHLDA3 TAP1 CDKN2B SFN ZMAT3 DDB2 EI24 PERP DDIT4 ATF3 BAX SESN1 FDXR PIDD SAT1 CDKN2A AEN PPM1D FOXO3 BTG1 TXNIP SLC19A2 IER3 TP53 NOTCH1 RRAD DCXR NINJ1 FOS S100A10 FBXW7 PLK3 XPC AK1 TRIAP1 BAK1 CCND2 APAF1 PDGFA NDRG1 RALGDS SERPINB5 DGKA CYFIP2 KLF4 IP6K2 ADA TNFSF9 KLK8 PRKAB1 STOM SOCS1 PLK2 CASP1 RCHY1 PCNA RPS27L RB1 PPP1R15A POLH RAB40C ERCC5 CDH13 DDIT3 TGFB1 FUCA1 HIST3H2A TP63 HSPA4L EPHX1 ABHD4 H2AFJ TRAF4 CTSF IER5 TAX1BP3 TSC22D1 RGS16 HRAS PVT1 ZFP36L1 SDC1 WRAP73 RAP2B ADCK3 PLXNB2 HEXIM1 PROCR SPHK1 NOL8 DEF6 SP1 JAG2 CCP110 DRAM1 RPL18 CEBPA KIF13B MXD1 TRAFD1 OSGIN1 ANKRA2 HBEGF RAD51C ITGB4 TRIB3 INHBB VAMP8 VWA5A ABAT CTSD PTPRE HINT1 ALOX15B VDR IKBKAP WWP1 NUPR1 TCN2 CDKN2AIP POM121 ZNF365 EPHA2 JUN MAPKAPK3 SLC7A11 SERTAD3 IRAK1 ABCC5 UPP1 CD81 LIF RPL36 FAM162A RNF19B CDK5R1 STEAP3 PITPNC1 SLC35D1 TPRKB RRP8 IL1A PMM1 TPD52L1 IFI30 GM2A RPS12 EPS8L2 TM4SF1 BLCAP MKNK2 CD82 GNB2L1 ST14 TCHH HDAC3 CCNK RHBDF2 NUDT15 TGFA ISCU LDHB TNNI1 FGF13 RXRA APP F2R CLCA2 CGRRF1 CSRNP2 ACVR1B BMP2 GPX2 KRT17 TM7SF3 ZBTB16 PTPN14 TSPYL2 SLC3A2 S100A4 GLS2 CCND3 PRMT2 NHLH2 BAIAP2 RETSAT LRMP HIST1H1C DNTTIP2 MXD4 SEC61A1 HMOX1 RAD9A
HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY GSR PRDX2 TXNRD1 SOD1 GCLC CAT GPX4 MPO PRDX1 PRDX6 GCLM TXN SOD2 PRDX4 SELS PDLIM1 TXNRD2 HBXIP G6PD MSRA MBP SRXN1 NQO1 OXSR1 GLRX2 HMOX2 FES PFKP NDUFB4 GPX3 SCAF4 CDKN2D MGST1 ABCC1 FTL ATOX1 STK25 EGLN2 ERCC2 SBNO2 JUNB PPP2R4 LSP1 NDUFA6 HHEX GLRX NDUFS2 PRNP IPCEF1
HALLMARK_OXIDATIVE_PHOSPHORYLATION http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_OXIDATIVE_PHOSPHORYLATION NDUFS3 UQCRB NDUFS2 SDHA UQCRC1 NDUFA9 NDUFS4 NDUFS1 NDUFA2 NDUFS8 SDHB NNT ATP5O ATP5G3 NDUFS7 ATP5A1 NDUFV1 COX5B UQCRH NDUFA1 ATP5C1 ATP5B COX7B SDHD CYCS NDUFA6 NDUFAB1 COX8A ACO2 ATP5G1 CYC1 NDUFB6 ATP5E COX5A UQCRC2 COX6A1 ATP5D COX6C ATP5J NDUFB3 IDH3B OGDH NDUFB8 SURF1 COX6B1 NDUFB5 NDUFA4 NDUFB1 COX4I1 COX7C UQCRFS1 SDHC ATP6V1F COX7A2 SUCLG1 NDUFS6 NDUFA7 FH NDUFV2 OXA1L NDUFC1 UQCR11 NDUFA5 CS ATP6V1G1 ATP5F1 HCCS HADHB ATP5H PDHA1 NDUFA8 DLD OPA1 SLC25A11 ATP5I PDHB ATP5J2 NDUFB7 IDH2 MTX2 VDAC3 MDH1 ATP5G2 IMMT MDH2 SLC25A3 ATP6V1D VDAC2 ACADM COX7A2L TIMM17A ATP6V1E1 NDUFA3 SLC25A6 IDH3G ACADVL ETFA TIMM9 IDH3A TIMM8B ATP6AP1 TIMM13 UQCRQ ABCB7 VDAC1 ATP5L PHB2 DECR1 SUCLA2 GOT2 DLAT ATP6V1H NDUFB2 FDX1 HADHA ATP6V1C1 MAOB NDUFB4 UQCR10 ETFDH GPX4 PDHX MFN2 AIFM1 ACAA2 ETFB COX11 ECHS1 PMPCA ATP6V0B SLC25A5 DLST COX15 CYB5A ALAS1 SLC25A4 CPT1A SLC25A20 MTRR COX17 CYB5R3 TOMM22 ACAT1 MRPS11 ATP6V0C PDK4 TIMM10 LDHA ECI1 MRPL11 FXN MRPS12 COX10 RHOT1 ACAA1 ACADSB LDHB MRPS30 ATP1B1 BDH2 SLC25A12 TIMM50 MRPL34 ISCA1 MRPL35 IDH1 HSPA9 MRPL15 MRPS15 TOMM70A TCIRG1 ISCU POLR2F NQO2 NDUFC2 MRPS22 POR ATP6V0E1 PHYH BRP44L GPI AFG3L2 HSD17B10 CASP7 PRDX3 MGST3 HTRA2 BCKDHA LRPPRC RETSAT ECH1 RHOT2 BAX MTRF1 GLUD1 SUPV3L1 GRPEL1 PDP1 ALDH6A1 OAT
HALLMARK_MYC_TARGETS_V2 http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MYC_TARGETS_V2 SLC19A1 MRTO4 TMEM97 RRP9 PES1 TFB2M EXOSC5 IPO4 NDUFAF4 NOC4L MYC SRM PA2G4 GNL3 NOLC1 WDR43 RABEPK NOP16 TBRG4 DDX18 NIP7 WDR74 BYSL HSPD1 PLK4 NOP2 PPAN NOP56 RCL1 NPM1 AIMP2 RRP12 PPRC1 TCOF1 MCM5 HK2 CBX3 PLK1 PHB MCM4 CDK4 DUSP2 MYBBP1A UTP20 PRMT3 FARSA MAP3K6 LAS1L PUS1 HSPE1 SLC29A2 DCTPP1 SUPV3L1 SORD IMP4 GRWD1 UNG MPHOSPH10
HALLMARK_MYC_TARGETS_V1 http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MYC_TARGETS_V1 PCNA PSMD8 PSMD7 SET SNRPA1 RAN SRSF2 G3BP1 STARD7 NPM1 BUB3 EIF3D XPO1 FBL EIF4A1 CANX NAP1L1 CBX3 CCT3 C1QBP U2AF1 UBE2L3 SSBP1 SRSF1 TCP1 MCM2 EIF3B PSMD14 SNRPA PWP1 APEX1 TXNL4A HNRNPR PSMB2 HPRT1 MCM6 NME1 SNRPD1 EEF1B2 HSPD1 CAD RPL18 PGK1 DDX18 RPS2 LDHA RUVBL2 RNPS1 EIF2S1 RANBP1 MCM5 IARS UBE2E1 MYC AP3S1 RFC4 DUT PSMA4 RPS3 SNRPG PHB2 SSB EIF4H SRSF3 CCT4 TFDP1 EIF2S2 CDK4 SNRPD3 PSMD1 GNB2L1 GOT2 PABPC4 CCT5 PRPS2 ACP1 PRPF31 CCT2 KARS DEK EIF4G2 XPOT SRM UBA2 KPNB1 PSMA7 TRA2B COX5A PA2G4 PCBP1 HNRNPA1 CCNA2 PPIA EIF3J ORC2 PSMA2 SYNCRIP HDAC2 LSM2 VBP1 PSMA6 CNBP CDK2 TARDBP NOLC1 GSPT1 HNRNPA2B1 ETF1 RPL6 TOMM70A PTGES3 PSMA1 PSMC6 CTPS HSPE1 FAM120A PPM1G HNRNPD SERBP1 CSTF2 PRDX4 EIF4E ODC1 USP1 RPL22 HNRNPA3 NCBP1 RPLP0 ABCE1 EIF1AX YWHAE MCM7 YWHAQ VDAC1 SMARCC1 SNRPD2 HNRNPU HDDC2 PSMD3 RRM1 SF3A1 LSM7 ERH RPL14 PSMB3 IFRD1 NCBP2 GLO1 NDUFAB1 CUL1 NHP2 CLNS1A TRIM28 RSL1D1 HNRNPC COPS5 XRCC6 SLC25A3 MRPL9 POLE3 POLD2 H2AFZ AIMP2 NOP56 PRDX3 MRPS18B EPRS KPNA2 HSP90AB1 RPL34 SRPK1 MAD2L1 DHX15 MCM4 RPS5 CCT7 HDGF RPS6 SNRPB2 PSMC4 CDC20 TUFM RRP9 CDC45 TYMS ILF2 VDAC3 IMPDH2 SF3B3 NOP16 SRSF7 GNL3 EXOSC7 MRPL23 RAD23B RPS10 PHB DDX21 CYC1 PABPC1
HALLMARK_E2F_TARGETS http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_E2F_TARGETS AURKA BRCA2 CCP110 CENPE CKS2 DCLRE1B DNMT1 DONSON EED GINS1 GINS4 H2AFZ LIG1 MAD2L1 MCM2 MCM4 MCM5 MCM7 MELK MMS22L NAA38 NASP NUDT21 NUP205 ORC6 PCNA PLK4 POLE PRIM2 RAD51AP1 RFC2 RPA2 RPA3 SUV39H1 TMPO UBE2T WDR90 CDK1 MCM3 TOP2A MCM6 BIRC5 CCNB2 RRM2 HMGB2 BUB1B RFC3 EZH2 CHEK1 SMC4 MKI67 CDC20 PLK1 KIF2C DLGAP5 AURKB CDC25A TRIP13 H2AFX HMMR E2F8 BRCA1 MYBL2 POLD1 RACGAP1 CKS1B KPNA2 MSH2 CDKN3 ATAD2 RPA1 STMN1 TIPIN TK1 CDCA8 ESPL1 NCAPD2 RANBP1 MRE11A KIF4A LMNB1 KIF22 UNG SMC1A CCNE1 CDCA3 ASF1B POLA2 TIMELESS HELLS UBE2S PRKDC RAN USP1 SPAG5 POLD3 DUT TACC3 KIF18B CDC25B SRSF1 GINS3 NOLC1 SLBP CHEK2 SPC25 BARD1 DCTPP1 SMC3 RNASEH2A DEK CENPM RAD51C CBX5 RFC1 POLD2 DSCC1 ILF3 DEPDC1 DCK CDKN2C MYC TCF19 RAD1 LBR NBN PTTG1 UBR7 POLE4 TUBG1 CTCF RQCD1 TUBB SMC6 ZW10 PA2G4 SSRP1 NAP1L1 ANP32E HMGB3 IPO7 RAD21 CDK4 CDKN1A BRMS1L CTPS RAD50 TRA2B CSE1L PAICS STAG1 LUC7L3 PPM1D NME1 SRSF2 XPO1 HNRNPD PMS2 ASF1A EXOSC8 MLH1 NUP107 ORC2 TP53 TFRC HMGA1 PSIP1 DDX39A SNRPB CDKN1B MTHFD2 WEE1 PRDX4 PHF5A TBRG4 SHMT1 PRPS1 DIAPH3 NUP153 PSMC3IP XRCC6 PNN HUS1 RBBP7 PDS5B NOP56 MXD3 PPP1R8 GSPT1 CDKN2A AK2 CIT ING3 HN1 POP7 SYNCRIP EIF2S1 LYAR PAN2 SPC24
HALLMARK_UNFOLDED_PROTEIN_RESPONSE http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UNFOLDED_PROTEIN_RESPONSE ATF4 HERPUD1 PARN EXOSC4 HSP90B1 XBP1 EXOSC9 HSPA5 ATF3 EXOSC1 EXOSC5 ASNS ARFGAP1 WFS1 SRPRB DNAJB9 TSPYL2 NFYA CALR KHSRP DNAJC3 EXOSC2 NOP14 ATF6 HYOU1 RRP9 NOP56 CXXC1 IGFBP1 CNOT4 DCP2 PDIA6 ATP6V0D1 PREB SEC31A GOSR2 SERP1 NFYB NHP2 DCTN1 SLC7A5 SSR1 EDEM1 EDC4 EIF2AK3 MTHFD2 SRPR NOLC1 ERN1 FKBP14 ZBTB17 WIPI1 YIF1A CCL2 DKC1 EIF4EBP1 EIF4A1 EIF2S1 TATDN2 XPOT LSM4 CHAC1 STC2 PDIA5 OBFC2A LSM1 SDAD1 EIF4A2 EIF4E IARS DDX10 GEMIN4 TARS ALDH18A1 DDIT4 HSPA9 SEC11A EIF4A3 POP4 ERO1L CEBPG BAG3 KDELR3 CEBPB CNOT2 SHC1 SPCS3 H2AFX SLC1A4 RPS14 NPM1 CNOT6 CKS1B PSAT1 EIF4G1 YWHAZ SLC30A5 SKIV2L2 KIF5B DCP1A IFIT1 IMP3 SPCS1 DNAJA4 VEGFA TTC37 TUBB2A FUS EXOSC10 EEF2 EXOC2 PAIP1 BANF1
HALLMARK_APOPTOSIS http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_APOPTOSIS CASP3 CASP9 DFFA CASP7 CFLAR BIRC3 PMAIP1 CASP8 JUN BCL2L11 MCL1 IL1B SPTAN1 DIABLO BAX BIK IL1A BID CDKN1A GADD45A DDIT3 CDKN1B TNF GSN TNFSF10 CASP6 SQSTM1 FASLG EGR3 CD44 FAS IL18 IGFBP6 PRF1 DAP CCND1 BTG3 F2R SATB1 BNIP3L CASP4 TNFRSF12A CREBBP RHOB GPX3 PDGFRB TSPO CCND2 XIAP TIMP1 CTNNB1 IRF1 HSPB1 ADD1 TIMP2 BTG2 TIMP3 LEF1 CASP1 GPX1 BCL10 IGF2R CDC25B AIFM3 CD38 PPP3R1 HGF CLU ATF3 LGALS3 LUM LMNA GADD45B CDK2 IFNB1 RETSAT SMAD7 SOD1 PTK2 ENO2 HMOX1 IER3 BCL2L10 CD2 GCH1 MMP2 VDAC2 TAP1 PLAT IFNGR1 APP BRCA1 ROCK1 PSEN1 DCN PSEN2 SOD2 BMF EREG KRT18 TGFB2 RELA WEE1 RARA CD14 CD69 PEA15 DNAJC3 CASP2 CTH PLCB2 BMP2 HMGB2 LPPR4 H1F0 TGFBR3 EBP TXNIP ANKH RHOT2 CYLD GSTM1 GSR BGN BCL2L1 GNA15 MGMT PPT1 F2 IL6 SC5DL IFITM3 RNASEL EMP1 CAV1 DNM1L ANXA1 TOP2A ISG20 SLC20A1 MADD PPP2R5B BCAP31 ERBB3 NEDD9 SAT1 PDCD4 BCL2L2 FEZ1 ERBB2 DNAJA1 DAP3 DPYD NEFH PAK1 FDXR GPX4 ETF1 CCNA1 GUCY2D AVPR1A
HALLMARK_G2M_CHECKPOINT http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_G2M_CHECKPOINT AURKA CCNA2 TOP2A CCNB2 CENPA BIRC5 CDC20 PLK1 TTK PRC1 NDC80 KIF11 NUSAP1 CKS2 KIF2C MKI67 AURKB TPX2 SMC4 BUB1 CENPF RACGAP1 CENPE KIF23 UBE2C MCM6 MCM3 PTTG1 CDK1 KIF4A ESPL1 MAD2L1 NEK2 KIF22 HMMR KPNA2 CDKN3 CDC25A H2AFX CDC25B PLK4 CDC6 CCNF MCM5 LMNB1 E2F3 KIF15 CHEK1 UBE2S WHSC1 HMGB3 DBF4 TACC3 MCM2 CDKN2C CDKN1B FANCC NASP STAG1 GINS2 FBXO5 POLQ EZH2 RAD21 STMN1 SUV39H1 PRIM2 E2F1 CHAF1A NOLC1 GSPT1 BUB3 SMC1A ILF3 CDC7 INCENP CKS1B EXO1 H2AFZ TFDP1 CCND1 KPNB1 HN1 LBR HUS1 KIF20B TOP1 PDS5B SRSF1 STIL ABL1 DTYMK CDC27 BARD1 ATF5 CDC45 ODC1 XPO1 SFPQ TMPO PML BRCA2 CTCF CASC5 SETD8 SLC38A1 TRA2B MYBL2 TROAP PAPD7 CUL3 MAPK14 HIST1H2BK MYC AMD1 CBX1 CHMP1A DKC1 YTHDC1 CCNT1 TGFB1 ATRX LIG3 NUP50 SLC7A5 RBL1 NUMA1 RAD54L EFNA5 PRPF4B UCK2 ARID4A CUL1 UPF1 DR1 MNAT1 SMC2 RBM14 RPA2 SQLE ORC6 CDK4 POLE RASAL2 HOXC10 RPS6KA5 CUL4A SLC7A1 FOXN3 HMGA1 SS18 TRAIP PRMT5 CUL5 DDX39A MARCKS PBK ORC5 SAP30 KATNA1 HNRNPD POLA2 HIRA HIF1A SYNCRIP TLE3 NCL RAD23B E2F2 EGF HMGN2 SRSF10 SNRPD1 CASP8AP2 SMARCC1 SLC12A2 NOTCH2 TNPO2 SMAD3 ZAK HSPA8 G3BP1 PTTG3P DMD MEIS1 HNRNPU SRSF2 MT2A NUP98 EWSR1 KIF5B MTF2 E2F4 BCL3 PURA MEIS2 PAFAH1B1 WRN H2AFV ODF2
HALLMARK_DNA_REPAIR http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_DNA_REPAIR POLR2H POLR2A POLR2G POLR2E POLR2J POLR2F POLR2C POLR2K GTF2H3 POLR2D ERCC3 DDB2 POLR1C XPC PCNA POLR2I SUPT4H1 POLD3 POLR3GL POLR3C GTF2B POLR1D NCBP2 RDBP GTF2F1 ERCC5 LIG1 ERCC1 ERCC4 POLD4 COBRA1 RFC2 ELL TAF10 RRM2B SUPT5H RPA3 SNAPC5 SSRP1 RFC3 RPA2 TCEB3 TAF12 TH1L TAF13 TAF6 TAF9 GTF2A2 VPS37D NME1 RNMT ERCC2 POLE4 VPS37B NT5C3 SNAPC4 AAAS ZNRD1 RFC4 ITPA POM121 BRF2 RFC5 SAC3D1 CLP1 NME4 PRIM1 VPS28 TSG101 USP11 TAF1C TARBP2 POLH CETN2 POLD1 CANT1 PDE4B DGCR8 RAD51 SURF1 PNP ADA NME3 GTF3C5 NT5C AK1 GTF2H1 HCLS1 APRT ERCC8 IMPDH2 POLB SDCBP SF3A3 DAD1 UPF3B GUK1 TP53 ADRM1 SEC61A1 POLA2 FEN1 ZNF707 NUDT9 PDE6G TYMS BCAP31 DDB1 NFX1 RAD52 ADCY6 ARL6IP1 DGUOK POLL SMAD5 MPG DUT POLA1 EIF2C4 RALA ZWINT BCAM TK2 CSTF3 GTF2H5 HPRT1 BOLA2 GPX4 BRP44 CDA THOC4 MRPL40 NPR2 REV3L EDF1 DFNA5 TMED2 STX3 RAE1 UMPS EIF1B AK3 NUDT21 RBX1 SRSF6 GMPR2 DCTN4 COX17 CMPK2 CCNO
HALLMARK_HYPOXIA http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HYPOXIA PGK1 PDK1 GBE1 PFKL ALDOA ENO2 PGM1 NDRG1 HK2 ALDOC GPI MXI1 SLC2A1 P4HA1 ADM P4HA2 ENO1 PFKP AK4 FAM162A PFKFB3 VEGFA BNIP3L TPI1 ERO1L KDM3A CCNG2 LDHA GYS1 GAPDH BHLHE40 ANGPTL4 JUN SERPINE1 LOX GCK PPFIA4 MAFF DDIT4 SLC2A3 IGFBP3 NFIL3 FOS RBPJ HK1 CITED2 ISG20 GALK1 WSB1 PYGM STC1 ZNF292 BTG1 PLIN2 CSRP2 VLDLR JMJD6 EXT1 F3 PDK3 ANKZF1 UGP2 ALDOB STC2 ERRFI1 ENO3 PNRC1 HMOX1 PGF GAPDHS CHST2 TMEM45A BCAN ATF3 CAV1 AMPD3 GPC3 NDST1 IRS2 SAP30 GAA SDC4 STBD1 IER3 PKLR IGFBP1 PLAUR PRKCDBP WISP2 LARGE CCRN4L S100A4 RRAGD ZFP36 EGFR EDN2 IDS CDKN1A RORA DUSP1 MIF PPP1R3C DPYSL4 KDELR3 DTNA ADORA2B HS3ST1 PTRF NR3C1 KLF6 GPC4 CYR61 TNFAIP3 CA12 HEXA BGN PPP1R15A PGM2 PIM1 PRDX5 NAGK CDKN1B BRS3 TKTL1 MT1E ATP7A MT2A SDC3 TIPARP PKP1 ANXA2 PGAM2 DDIT3 PRKCA SLC37A4 CXCR4 EFNA3 CP KLF7 CTGF CHST3 TPD52 LXN B4GALNT2 PPARGC1A BCL2 GCNT2 HAS1 KLHL24 SCARB1 SLC25A1 SDC2 CASP6 VHL FOXO3 PDGFB B3GALT6 SLC2A5 SRPX EFNA1 GLRX CXCR7 PAM TGFBI DCN SIAH2 PLAC8 FBP1 TPST2 PHKG1 MYH9 CDKN1C GRHPR PCK1 INHA HSPA5 NDST2 NEDD4L TPBG XPNPEP1 IL6 SLC6A6 MAP3K1 LDHC AKAP12 TES KIF5A LALBA COL5A1 GPC1 HDLBP ILVBL NCAN TGM2 ETS1 HOXB9 SELENBP1 FOSL2 SULT2B1 TGFB3
HALLMARK_MTORC1_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MTORC1_SIGNALING FADS1 DDIT4 CALR HK2 PGK1 SLC7A5 CTSC ACSL3 SLC1A5 M6PR TFRC DDIT3 TMEM97 IFRD1 PLOD2 TUBA4A PSAT1 CORO1A LDHA MTHFD2 FADS2 VLDLR WARS SCD P4HA1 ACTR2 IDH1 SLC2A1 GBE1 SERPINH1 NUPR1 PSMG1 PSPH NAMPT CDKN1A BHLHE40 HSPA9 HSPA5 EGLN3 LGMN PNP XBP1 SLA DDX39A HSPE1 ACLY SLC7A11 SSR1 GLA SQSTM1 PDK1 PSMC2 PRDX1 SERP1 TRIB3 NFIL3 HMGCS1 GOT1 TPI1 ELOVL6 ASNS PSMD14 PSMA4 PPA1 HPRT1 AURKA HMGCR GAPDH DHFR DHCR7 IMMT UCHL5 YKT6 INSIG1 SQLE IGFBP5 IFI30 CYP51A1 FGL2 ENO1 IDI1 CYB5B SHMT2 TXNRD1 G6PD SLC9A3R1 RAB1A EBP PNO1 PIK3R3 ACTR3 LDLR SLC2A3 UBE2D3 ELOVL5 CACYBP EDEM1 ATP6V1D TES TM7SF2 PSMA3 ITGB2 AK4 SLC1A4 TOMM40 SLC6A6 PPIA ADD3 ME1 CCNF SLC37A4 ALDOA BTG2 UFM1 CCNG1 STC1 NMT1 PSMC6 FDXR RRM2 DHCR24 PSMC4 CTH PSME3 CFP POLR3G ACACA QDPR MCM2 PSMD12 SC5DL CANX RPN1 HSPA4 FAM129A TBK1 SEC11A BCAT1 PSMB5 PSMD13 PGM1 PLK1 GLRX COPS5 ETF1 GSK3B NUP205 SORD PHGDH GMPS RRP9 EEF1E1 LTA4H SDF2L1 FKBP2 RDH11 CXCR4 MLLT11 GCLC TCEA1 MAP2K3 HSPD1 SYTL2 MCM4 PPP1R15A USO1 NFKBIB UNG GTF2H1 RPA1 HSP90B1 ERO1L GSR PITPNB EPRS SRD5A1 TUBG1 MTHFD2L ADIPOR2 NUFIP1 CDC25A PDAP1 STARD4 BUB1 ARPC5L GPI EIF2S2 CD9 ATP2A2 GGA2 HMBS RIT1 SKAP2 STIP1 DAPP1 ABCF2 NFYC ATP5G1 PFKL CCT6A
HALLMARK_TNFA_SIGNALING_VIA_NFKB http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_TNFA_SIGNALING_VIA_NFKB JUNB CXCL2 ATF3 NFKBIA TNFAIP3 PTGS2 CXCL1 IER3 CD83 CCL20 CXCL3 MAFF NFKB2 TNFAIP2 HBEGF KLF6 BIRC3 PLAUR ZFP36 ICAM1 JUN EGR3 IL1B BCL2A1 PPP1R15A ZC3H12A SOD2 NR4A2 IL1A RELB TRAF1 BTG2 DUSP1 MAP3K8 ETS2 F3 SDC4 EGR1 IL6 TNF KDM6B NFKB1 LIF PTX3 FOSL1 NR4A1 JAG1 CCL4 GCH1 CCL2 RCAN1 DUSP2 EHD1 IER2 REL CFLAR RIPK2 NFKBIE NR4A3 PHLDA1 IER5 TNFSF9 GEM GADD45A CXCL10 PLK2 BHLHE40 EGR2 SOCS3 SLC2A6 PTGER4 DUSP5 SERPINB2 NFIL3 SERPINE1 TRIB1 TIPARP RELA BIRC2 CXCL6 LITAF TNFAIP6 CD44 INHBA PLAU MYC TNFRSF9 SGK1 TNIP1 NAMPT FOSL2 PNRC1 ID2 CD69 IL7R EFNA1 PHLDA2 PFKFB3 CCL5 YRDC IFNGR2 SQSTM1 BTG3 GADD45B KYNU G0S2 BTG1 MCL1 VEGFA MAP2K3 CDKN1A CYR61 TANK IFIT2 IL18 TUBB2A IRF1 FOS OLR1 RHOB AREG NINJ1 ZBTB10 PPAP2B KLF4 CXCL11 SAT1 CSF1 GPR183 PMEPA1 PTPRE TLR2 CXCR7 KLF10 MARCKS LAMB3 CEBPB TRIP10 F2RL1 KLF9 LDLR TGIF1 RNF19B DRAM1 B4GALT1 DNAJB4 CSF2 PDE4B SNN PLEK STAT5A DENND5A CCND1 DDX58 SPHK1 CD80 TNFAIP8 CCNL1 FUT4 CCRL2 SPSB1 TSC22D1 B4GALT5 SIK1 CLCF1 NFE2L2 FOSB PER1 NFAT5 ATP2B1 IL12B IL6ST SLC16A6 ABCA1 HES1 BCL6 IRS2 SLC2A3 CEBPD IL23A SMAD3 TAP1 MSC IFIH1 IL15RA TNIP2 BCL3 PANX1 FJX1 EDN1 EIF1 BMP2 DUSP4 PDLIM5 ICOSLG GFPT2 KLF2 TNC SERPINB8 MXD1
HALLMARK_TGF_BETA_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_TGF_BETA_SIGNALING TGFBR1 SMAD7 TGFB1 SMURF2 SMURF1 BMPR2 SKIL SKI ACVR1 PMEPA1 NCOR2 SERPINE1 JUNB SMAD1 SMAD6 PPP1R15A TGIF1 FURIN SMAD3 FKBP1A MAP3K7 BMPR1A CTNNB1 HIPK2 KLF10 BMP2 ENG APC PPM1A XIAP CDH1 ID1 LEFTY2 CDKN1C TRIM33 RAB31 TJP1 SLC20A1 CDK9 ID3 NOG ARID4B IFNGR2 ID2 PPP1CA SPTBN1 WWTR1 BCAR3 THBS1 FNTA HDAC1 UBE2D3 LTBP2 RHOA
HALLMARK_WNT_BETA_CATENIN_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_WNT_BETA_CATENIN_SIGNALING MYC CTNNB1 JAG2 NOTCH1 DLL1 AXIN2 PSEN2 FZD1 NOTCH4 LEF1 AXIN1 NKD1 WNT5B CUL1 JAG1 MAML1 KAT2A GNAI1 WNT6 PTCH1 NCOR2 DKK4 HDAC2 DKK1 TCF7 WNT1 NUMB ADAM17 DVL2 PPARD NCSTN HDAC5 CCND2 FRAT1 CSNK1E RBPJ FZD8 TP53 SKP2 HEY2 HEY1 HDAC11
HALLMARK_NOTCH_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_NOTCH_SIGNALING JAG1 NOTCH3 NOTCH2 APH1A HES1 CCND1 FZD1 PSEN2 FZD7 DTX1 DLL1 FZD5 MAML2 NOTCH1 PSENEN WNT5A CUL1 WNT2 DTX4 SAP30 PPARD KAT2A HEYL SKP1 RBX1 TCF7L2 ARRB1 LFNG PRKCA DTX2 ST3GAL6 FBXW11
HALLMARK_PI3K_AKT_MTOR_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_PI3K_AKT_MTOR_SIGNALING MAPK8 PIK3R3 GRB2 NFKBIB MAP2K6 MAPK9 AKT1 MAPK1 PLCG1 TRIB3 GSK3B MAP2K3 CDKN1A RAC1 RIPK1 AKT1S1 ACTR2 PRKAR2A YWHAB HRAS PDK1 PIKFYVE TBK1 ACTR3 E2F1 MYD88 ITPR2 SQSTM1 RPS6KA1 PTPN11 MAPKAP1 PLCB1 RAF1 CAMK4 RPTOR CFL1 CDK4 TRAF2 GNGT1 UBE2N ADCY2 CDKN1B VAV3 FGF6 ECSIT RALB ARF1 MKNK1 CDK1 PTEN ARHGDIA ADRBK1 FGF17 DDIT3 IRAK4 TIAM1 CDK2 SFN PRKCB GNA14 EIF4E CLTC TSC2 FGF22 PPP1CA DUSP3 HSP90B1 IL4 STAT2 SLA EGFR PLA2G12A MAPK10 CALR THEM4 RIT1 MKNK2 PPP2R1B CAB39L ARPC3 PITX2 NCK1 IL2RG PFN1 FASLG NOD1 DAPP1 UBE2D3 CAB39 AP2M1 MAP3K7 PRKAG1 CSNK2B PRKAA2 ATF1 SLC2A1 PIN1 TNFRSF1A LCK RPS6KA3 NGF CXCR4 ACACA SMAD2 PAK4
HALLMARK_HEDGEHOG_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HEDGEHOG_SIGNALING SHH PTCH1 NRCAM NRP1 SCG2 AMOT UNC5C GPR56 HEY1 GLI1 THY1 SLIT1 CDK6 HEY2 NRP2 TLE3 TLE1 L1CAM PLG NKX6-1 NF1 RASA1 ETS2 RTN1 CRMP1 MYH9 VEGFA CELSR1 CNTFR ACHE PML CDK5R1 VLDLR OPHN1 LDB1 DPYSL2
HALLMARK_CANCER_PREDISPOSITION_LEUKEMIA http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_CANCER_PREDISPOSITION_LEUKEMIA ABL2 ADAR AK2 ARID1A BCL10 C1QA C1QB C1QC C8A C8B CAMTA1 CASP9 CD247 CD46 CD55 CDC73 CDKN2C CFH COPA CR2 CSF3R CTPS1 DCLRE1B EXO1 FASLG FCGR3A FCN3 FH GBA GFI1 HAX1 IL10 IRF2BP2 ISG15 JAK1 KIF1B LAMTOR2 LCK LYST MAD2L2 MASP2 MPL MUC1 MUTYH MYSM1 NCF2 NLRP3 NRAS NTRK1 PIK3CD PSMB4 PTPRC RBM8A RFX5 RIT1 RORC RPL11 RPL5 RPS27 SDHB SDHC SEMA4A SPRTN TNFRSF4 TNFRSF9 UBE2T UROD VPS45 ABCB11 ADAM17 ALK BARD1 BUB1 CASP10 CASP8 CD8A COLEC11 CTLA4 CXCR2 CXCR4 DIS3L2 EPCAM ERCC3 FANCL ICOS IDH1 IFIH1 IL1RN IL36RN MOGS MSH2 MSH6 NHEJ1 NLRC4 PMS1 RANBP2 RPL31 RPS27A RPS7 SMARCAL1 SOS1 SP110 STAT1 TMEM127 TTC7A WIPF1 ZAP70 ATR BAP1 COL7A1 DNASE1L3 FANCD2 FHIT FOXP1 GATA2 IL17RC JAGN1 MASP1 MECOM MITF MLH1 MYD88 OGG1 PBRM1 PRKCD RAF1 RNF168 RPL15 RPL35A RPSA SETMAR TERC TFRC TGFBR2 TREX1 TRNT1 VHL XPC CFI FBXW7 FGFR3 IL21 KDR KIT LRBA NAF1 NFKB1 PDGFRA PHOX2B RHOH RPL34 SRP72 TET2 TLR3 WDR1 AP3B1 APC C6 C7 C9 CTNNA1 DDX41 DNAJC21 DOCK2 DROSHA ERBIN GDNF IL12B IL6ST IL7R ITK NHP2 NKX2-5 NSD1 OTULIN PDGFRB PIK3R1 PRDM9 RAD50 RASA1 SDHA SPINK5 SQSTM1 TERT TMEM173 BACH2 C2 C4A C4B CDKN1A CFB FANCE FOXO3 HFE HSPA1L IFNGR1 IGF2R IL17F NFKBIE PGM3 POLH PRDM1 PRKN PSMB8 PSMB9 ROS1 RPL10A RPS10 STX11 TAP1 TAP2 TAPBP TFAP2A TNFAIP3 TRAF3IP2 ZBTB24 ACTB ARPC1B BRAF CARD11 CFTR EGFR GLI3 IKZF1 MDH2 MET NCF1 PMS2 POLD2 POT1 PRSS1 RINT1 SAMD9 SAMD9L SBDS SLC25A13 SMO TRIM24 XRCC2 EXT1 EXTL3 FGFR1 IKBKB MCM4 NBN NDRG1 PRKDC RECQL4 VPS13B WRN ABL1 C5 C8G CARD9 CDKN2A DOCK8 ERCC6L2 FANCC FANCG JAK2 LRRC8A MTAP NOTCH1 NR4A3 PAX5 PTCH1 RMRP RPL35 SMARCA2 SYK TGFBR1 TSC1 XPA ANKRD26 ARID5B BLNK BMPR1A BUB3 CHUK DCLRE1C ERCC6 FAS FGFR2 GATA3 HABP2 HELLS IL2RA JMJD1C KLF6 KLLN NCOA4 NFKB2 PRF1 PTEN RET RPS24 SFTPA1 SFTPA2 SHOC2 SLC29A3 STN1 SUFU TCF7L2 ARHGEF12 ATM CBL CD3D CD3E CD3G CD59 CD81 CDKN1C CLPB CTR9 CTSC DDB2 DHCR7 EXT2 FADD FANCF FERMT3 H19 HMBS HRAS HYOU1 IL10RA KCNQ1OT1 LMO1 MEN1 MRE11 MS4A1 MUC5B PTPRJ RAG1 RAG2 RELA RNASEH2C SDHAF2 SDHD SERPING1 SLC35C1 SLC37A4 STIM1 TCIRG1 TIRAP TPP1 UNC93B1 WT1 ZBTB16 AICDA ARID2 C1R C1S CD27 CDK4 CDKN1B CLEC7A DDX11 ETV6 HNF1A IRAK4 KRAS LRIG3 MVK ORAI1 POLE PTPN11 RECQL RPLP0 RPS26 SH2B3 STAT2 TBK1 TNFRSF1A UNG WIF1 BRCA2 CENPJ ERCC5 FLT3 FOXO1 GJB2 LIG4 POMP RB1 RFXAP RNASEH2B SMAD9 TPP2 AKT1 BCL11B CEBPE DICER1 FANCM L2HGDH MAX MTHFD1 NFKBIA PNP POLE2 PSMA3 RNF31 RPS29 SERPINA1 SRP54 TINF2 TRAC TRAF3 TSHR XRCC3 AP4E1 BLM BLOC1S6 BUB1B EFL1 FAH FAN1 FANCI GREM1 KNSTRN MAP2K1 NOP10 NTRK3 PML PSTPIP1 RAB27A RAD51 RASGRP1 RPS17 SPPL2A SPRED1 ACD ARMC5 CARMIL2 CBFA2T3 CD19 CDH1 CDH11 CIITA CORO1A CREBBP CYBA CYLD DNASE1 ERCC4 FANCA IL21R IRF8 LAT MAF MEFV NFAT5 NOD2 NTHL1 PALB2 PARN PLCG2 RPS15A SLX4 SOCS1 TSC2 USB1 AXIN2 BRCA1 BRIP1 CARD14 CD79B CTC1 CYBC1 ERBB2 FLCN FOXN1 G6PC3 HOXB13 IKZF3 MAP2K4 MAP3K14 MPO NF1 NLRP1 PRKAR1A RAD51C RAD51D RHBDF2 RPL19 RPL23 RPL26 RPL27 SLC46A1 SMARCD2 SMARCE1 STAT3 STAT5B TMC6 TMC8 TNFRSF13B TNFSF12 TP53 TRIM37 UNC119 UNC13D WRAP53 DSG1 LPIN2 MALT1 SETBP1 SMAD4 TNFRSF11A ACP5 AP3D1 C3 CD70 CD79A CEBPA CFD DNASE2 ELANE ERCC1 ERCC2 FAAP24 FPR1 IL12RB1 IRF3 JAK3 MAP2K2 NFIX NFKBIB NLRP12 POLD1 RELB RFXANK RNASEH2A RPL18 RPL36 RPS11 RPS15 RPS19 RPS28 SMARCA4 STK11 STXBP2 TCF3 TICAM1 TYK2 ADA ASXL1 CD40 DNMT3B GINS1 GNAS ITCH MAFB RBCK1 RTEL1 SAMHD1 STK4 AIRE ERG IFNGR2 IL10RB ITGB2 RUNX1 ALG12 APOL1 BCR CECR1 CHEK2 EP300 IGLL1 IL17RA LZTR1 MN1 MRTFA MYH9 NCF4 NF2 RAC2 RPL3 SMARCB1 TBX1 TCN2 TNFRSF13C USP18 XRCC6 ALAS2 ATP6AP1 BTK CD40LG CFP CSF2RA CYBB DKC1 FANCB FMR1 FOXO4 FOXP3 G6PD GATA1 GPC3 IKBKG IL2RG MAGT1 MECP2 MSN PHF6 PIGA POLA1 RPL10 SH2D1A TAZ TFE3 TSR2 WAS XIAP SRY