chemical_compound.mcf

Node: dcid:ActiveIngredientAmount
name: "ActiveIngredientAmount"
typeOf: schema:Class
subClassOf: schema:Drug
description: "Tells how much of the active ingredient is present in a drug dosage."

Node: dcid:AnatomicalTherapeuticChemicalCode
name: "AnatomicalTherapeuticChemicalCode"
typeOf: schema:Class
subClassOf: schema:Intangible,dcs:ChemicalSubstance
shortDisplayName: "ATC Code"
description: "In the ATC classification system, the active substances are classified in a hierarchy with five different levels. The system has fourteen main anatomical/pharmacological groups or 1st levels. Each ATC main group is divided into 2nd levels which could be either pharmacological or therapeutic groups. The 3rd and 4th levels are chemical, pharmacological or therapeutic subgroups and the 5th level is the chemical substance. The 2nd, 3rd and 4th levels are often used to identify pharmacological subgroups when that is considered more appropriate than therapeutic or chemical subgroups."
descriptionUrl: "https://www.whocc.no/atc/structure_and_principles/"

Node: dcid:Antibody
name: "Antibody"
typeOf: schema:Class
subClassOf: dcs:Protein
description: "An antibody is a kind of protective protein which is produced by the immune system when substances from the outer source invade the living organisms. The process of producing the antibodies is called immune response."

Node: dcid:BiomedicalEntity
name: "BiomedicalEntity"
typeOf: schema:Class
subClassOf: dcs:Thing
description: "Biomedical related entities."

Node: dcid:ChemicalCompound
name: "ChemicalCompound"
typeOf: schema:Class
subClassOf: dcs:ChemicalSubstance
description: "Chemical compound."
descriptionUrl: "https://www.ebi.ac.uk/chembl/"

Node: dcid:ChemicalCompoundAssociation
name: "ChemicalCompoundAssociation"
typeOf: schema:Class
subClassOf: dcs:ChemicalCompound
description: "Observed association between a chemical compound and another entity type."

Node: dcid:ChemicalCompoundChemicalCompoundAssociation
name: "ChemicalCompoundChemicalCompoundAssociation"
typeOf: schema:Class
subClassOf: dcs:ChemicalCompoundAssociation,dcs:DiseaseAssociation
description: "Two chemcial compounds that are associated with one another typically due to reacting with one another."

Node: dcid:ChemicalCompoundDiseaseContraindication
name: "ChemicalCompoundDiseaseContraindication"
typeOf: schema:Class
subClassOf: dcs:ChemicalCompoundAssociation,dcs:DiseaseAssociation
description: "Compound that is inadvisable to be used to treat a given disease."
descriptionUrl: "https://www.ebi.ac.uk/chembl/"

Node: dcid:ChemicalCompoundDiseaseTreatment
name: "ChemicalCompoundDiseaseTreatment"
typeOf: schema:Class
subClassOf: dcs:ChemicalCompoundAssociation,dcs:DiseaseAssociation
description: "Compound associated with the treatment of a given disease."
descriptionUrl: "https://www.ebi.ac.uk/chembl/"

Node: dcid:ChemicalCompoundGeneAssociation
name: "ChemicalCompoundGeneAssociation"
typeOf: schema:Class
subClassOf: dcs:ChemicalCompoundAssociation,dcs:GeneticAssociation
description: "The association of a chemical compound with a gene."

Node: dcid:ChemicalCompoundGeneticVariantAssociation
name: "ChemicalCompoundGeneticVariantAssociation"
typeOf: schema:Class
subClassOf: dcs:ChemicalCompoundAssociation,dcs:GeneticAssociation
description: "The association between a chemical compound, typically a drug, and a genetic variant."

Node: dcid:ChemicalCompoundProteinInteraction
name: "ChemicalCompoundProteinInteraction"
typeOf: schema:Class
subClassOf: dcs:ChemicalCompoundAssociation
description: "Interaction between a compound and a protein."
descriptionUrl: "https://www.ebi.ac.uk/chembl/"

Node: dcid:Drug
name: "Drug"
typeOf: schema:Class
subClassOf: dcs:ChemicalCompound
description: "A chemical or biologic substance, used as a medical therapy, that has a physiological effect on an organism. Here the term drug is used interchangeably with the term medicine although clinical knowledge make a clear difference between them."

Node: dcid:DrugStrength
name: "DrugStrength"
typeOf: schema:Class
subClassOf: schema:Drug
description: "A specific strength in which a medical drug is available in a specific country."

Node: dcid:FDAApplication
name: "FDAApplication"
typeOf: schema:Class
subClassOf: schema:Thing
description: "An application filing for approval of one or more drug products with the FDA."
descriptionUrl: "https://www.accessdata.fda.gov/scripts/cder/daf/"

Node: dcid:HumanProteinOccurrence
name: "HumanProteinOccurrence"
typeOf: schema:Class
subClassOf: schema:Intangible
description: "The Tissue Atlas contains information regarding the expression profiles of human genes both on the mRNA and protein level. The protein expression data from 44 normal human tissue types is derived from antibody-based protein profiling using immunohistochemistry."
descriptionUrl: "https://www.proteinatlas.org/humanproteome/tissue"

Node: dcid:MedicalEntity
name: "MedicalEntity"
typeOf: schema:Class
subClassOf: dcs:BiomedicalEntity

Node: dcid:Protein
name: "Protein"
typeOf: schema:Class
subClassOf: dcs:ChemicalCompound
description: "A class of nitrogenous organic compounds that are composed of large molecules called amino acids. These are essential for life in all living organisms."
descriptionUrl: "https://www.uniprot.org/"

Node: dcid:ProteinProteinInteraction
name: "ProteinProteinInteraction"
typeOf: schema:Class
subClassOf: dcs:ChemicalCompoundAssociation
description: "A highly specific physical contact between two or more proteins as a result of a biochemical event."

Node: dcid:USAdoptedNameStem
name: "USAdoptedNameStem"
typeOf: schema:Class
subClassOf: schema:Intangible,dcs:ChemicalSubstance
shortDisplayName: "USAN Stem"
description: "A common stem for which chemical and/or pharmacologic parameters have been established. This is designated by the United States Adopted Names (USAN) Council."
descriptionUrl: "https://www.ama-assn.org/about/united-states-adopted-names/united-states-adopted-names-approved-stems"

Node: dcid:activeIngredient
name: "activeIngredient"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: schema:Drug
description: "Any component that provides pharmacological activity or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease, or to affect the structure or any function of the body of man or animals."
descriptionUrl: "https://www.fda.gov/drugs/drug-approvals-and-databases/drugsfda-glossary-terms#A"

Node: dcid:additionalDrugInformation
name: "additionalDrugInformation"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: schema:Drug
description: "Additional information associated with a drug."

Node: dcid:abcdID
typeOf: schema:Property
name: "abcdID"
description: "The accession identifier of the antibody in the ABCD antibody database. "
rangeIncludes: schema:Text
domainIncludes: dcs:Antibody
descriptionUrl:"https://web.expasy.org/abcd/"

Node: dcid:addgeneID
typeOf: schema:Property
name: "addgeneID"
description: "The identifier for antibodies in Addgene. They distribute 89,594 plasmids on behalf of 4,322 labs from around the world. They also produce 480 ready-to-use viral vectors from our plasmid collection."
rangeIncludes: schema:Text
domainIncludes: dcs:Antibody
descriptionUrl:"https://www.addgene.org/"

Node: dcid:administrationRoute
name: "administrationRoute"
typeOf: schema:Property
rangeIncludes: dcs:AdministrationRouteEnum
domainIncludes: schema:Drug
description: "The method by which a drug is administered."

Node: dcid:alternateNCBIProteinAccessionNumber
name: "alternateNCBIProteinAccessionNumber"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: dcs:Protein
description: "Alternate NCBI accession number associated with a protein."

Node: dcid:aminoAcidSequence
name: "aminoAcidSequence"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: dcs:Protein
description: "The amino acid sequence for protein using IUPAC one letter codes for amino acids."

Node: dcid:antibodyApplication
typeOf: schema:Property
name: "antibodyApplication"
description: "The applications of the antibody in the experiments, such as ELISA, Immunofluorescence, Immunoprecipitation, etc."
rangeIncludes: schema:Text
domainIncludes: dcs:Antibody

Node: dcid:antibodyType
typeOf: schema:Property
name: "antibodyType"
description: "The type of antibody, including bispecific antibody, nanobody and DARPins. "
rangeIncludes: dcs:AntibodyTypeEnum
domainIncludes: dcs:Antibody

Node: dcid:antigenType
typeOf: schema:Property
name: "antigenType"
description: "The type of the antigen for an antibody which includes protein, chemical compound and other types. "
rangeIncludes: dcs:Protein
domainIncludes: dcs:Antibody

Node: dcid:applicationType
name: "applicationType"
typeOf: schema:Property
rangeIncludes: dcs:ApplicationTypeEnum
domainIncludes: dcs:FDAApplication
description: "The type of drug product approval application submitted to the FDA."

Node: dcid:atcCode
name: "atcCode"
typeOf: schema:Property
domainIncludes: dcs:AnatomicalTherapeuticChemicalCode
rangeIncludes: schema:Text
description: "A unique code assigned to a medicine according to the organ or system it works on and how it works. The classification system is maintained by the World Health Organization (WHO)."
descriptionUrl: "https://www.ema.europa.eu/en/glossary/atc-code"

Node: dcid:averageDailyDosage
name: "averageDailyDosage"
typeOf: schema:Property
domainIncludes: dcs:AnatomicalTherapeuticChemicalCode
rangeIncludes: schema:Quantity
description: "The assumed average maintenance dose per day for a drug used for its main indication in adults."
descriptionUrl: "https://www.whocc.no/ddd/definition_and_general_considera/"

Node: dcid:bindingDBID
name: "bindingDBID"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: dcs:Protein,dcs:ChemicalCompound
description: "BindingDB identifier of a protein."

Node: dcid:bgeeID
name: "bgeeID"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: dcs:Protein
description: "Bgee (gene expression data in animals database) identifier of a protein."

Node: dcid:canadianDrugsProductDatabaseDrugIdNumber
name: "canadianDrugsProductDatabaseDrugIdNumber"
typeOf: schema:Property
domainIncludes: schema:Drug
rangeIncludes: schema:Number
description: "The Canadian Drug Product Database (DPD) contains product specific information on drugs approved for use in Canada, and includes human pharmaceutical and biological drugs, veterinary drugs and disinfectant products. The drug identification number (DIN) is the id used to find a drug in this database."
sameAs: "https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html"
abbreviation: "Canadian DPD ID"

Node: dcid:cellosaurusID
typeOf: schema:Property
name: "cellosaurusID"
description: "The identifier of cell line in Cellosaurus. The Cellosaurus is a knowledge resource on cell lines. It attempts to describe all cell lines used in biomedical research."
rangeIncludes: schema:Text
domainIncludes: dcs:Antibody
descriptionUrl:"https://web.expasy.org/cellosaurus/"

Node: dcid:chemblID
name: "chemblID"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: dcs:ChemicalCompound
description: "ChEMBL identifier."

Node: dcid:clinicalAnnotationCount
name: "clinicalAnnotationCount"
typeOf: schema:Property
domainIncludes: dcs:BiomedicalEntity
rangeIncludes: schema:Number
description: "Clinical annotations provide information about variant-drug pairs based on variant annotations and incorporating variant-specific prescribing guidance from clinical guidelines and FDA approved drug labels, when available. PharmGKB scientific curators manually review variant annotations and create genotype-based summaries describing the phenotypic impact of the variant. The clinical annotation is given a score, based on the scores of the supporting annotations. A clinical annotation's score is used by PharmGKB curators in the process of assigning a Level of Evidence to the annotation. Levels range from 1-4, with level 1 meeting the highest criteria. This is the number of such reports associated with a given drug or genetic variant."
descriptionUrl: "https://www.pharmgkb.org/clinicalAnnotations"

Node: dcid:clinicalAnnotationCountLevel1_2
name: "clinicalAnnotationCountLevel1_2"
typeOf: schema:Property
domainIncludes: dcs:BiomedicalEntity
rangeIncludes: schema:Number
description: "Clinical annotations provide information about variant-drug pairs based on variant annotations and incorporating variant-specific prescribing guidance from clinical guidelines and FDA approved drug labels, when available. PharmGKB scientific curators manually review variant annotations and create genotype-based summaries describing the phenotypic impact of the variant. The clinical annotation is given a score, based on the scores of the supporting annotations. A clinical annotation's score is used by PharmGKB curators in the process of assigning a Level of Evidence to the annotation. Levels range from 1-4, with level 1 meeting the highest criteria. This is the number of such reports associated with a given drug or genetic variant whose evidence is at Level 1A, 1B, 2A, or 2B."
descriptionUrl: "https://www.pharmgkb.org/clinicalAnnotations"

Node: dcid:clinicalGuidelineAnnotationCount
name: "clinicalGuidelineAnnotationCount"
typeOf: schema:Property
domainIncludes: dcs:BiomedicalEntity
rangeIncludes: schema:Number
description: "PGx-based drug dosing guidelines published by multiple sources. Annotations present a brief summary of the genotype-based dosing recommendations, including selected excerpts from the guidelines, and links to the source publications/documents. Tags indicate if the guideline provides dosing information, states that a drug is either indicated or contraindicated, or gives other guidance based on genotype/metabolizer phenotype. This is the number of clinical guidelines associated with a given drug, genetic variant, or phenotype."
descriptionUrl: "https://www.pharmgkb.org/guidelineAnnotations"

Node: dcid:compoundID
name: "compoundID"
typeOf: schema:Property
rangeIncludes: dcs:ChemicalCompound
domainIncludes: dcs:ChemicalCompound
description: "The ChemicalCompound node associated with the current node."

Node: dcid:confidenceScore
typeOf: schema:Property
name: "confidenceScore"
description: "The confidence score of a protein-protein interaction and the source in which it is recorded."
rangeIncludes: schema:Quantity
domainIncludes: dcs:ProteinProteinInteraction

Node: dcid:dailyMedSetId
name: "dailyMedSetId"
typeOf: schema:Property
domainIncludes: schema:Drug
rangeIncludes: schema:Text
description: "The DailyMed database contains labeling for FDA-approved products and additional products regulated, but not approved, by the FDA. These drug labels are submitted to the Food and Drug Administration (FDA) by companies. The Set ID uniquely identifies a drug label in the DailyMed database."
sameAs: "https://dailymed.nlm.nih.gov/dailymed/"

Node: dcid:detectedProtein
typeOf: schema:Property
name: "detectedProtein"
description: "The protein whose levels are being assessed."
rangeIncludes: dcs:Protein
domainIncludes: dcs:HumanProteinOccurrence

Node: dcid:digitalObjectID
typeOf: schema:Property
name: "digitalObjectID"
rangeIncludes: schema:Text
domainIncludes: dcs:Thing
description: "Digital object identifier (doi) generated by the International DOI Foundation (IDF)."
descriptionUrl: "https://www.doi.org/"

Node: dcid:diseaseID
name: "diseaseID"
typeOf: schema:Property
rangeIncludes: dcs:Disease,dcs:MeSHDescriptor
domainIncludes: dcs:DiseaseAssociation
description: "Identifier for disease in a compound-disease treatment."

Node: dcid:dosageForm
name: "dosageForm"
typeOf: schema:Property
rangeIncludes: dcs:DosageFormEnum
domainIncludes: schema:Drug
description: "A dosage form is the physical form in which a drug is produced and dispensed, such as a tablet, a capsule, or an injectable."
descriptionUrl: "https://www.fda.gov/drugs/drug-approvals-and-databases/drugsfda-glossary-terms#form"

Node: dcid:dosageGuideline
name: "dosageGuideline"
typeOf: schema:Property
domainIncludes: dcs:Drug
rangeIncludes: schema:Boolean
description: "Indicates if there is a dosage guideline for a drug."

Node: dcid:dosageGuidelineSource
name: "dosageGuidelineSource"
typeOf: schema:Property
domainIncludes: schema:Drug
rangeIncludes: dcs:DosageGuidelineSourceEnum
description: "A professional society that provides dosage guidelines for a drug."

Node: dcid:drugBankID
name: "drugBankID"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: dcs:ChemicalCompound
description: "DrugBank identifier of compound."

Node: dcid:drugBrandMixture
name: "drugBrandMixture"
typeOf: schema:Property
domainIncludes: schema:Drug
rangeIncludes: schema:Text
description: "Known brand mixtures this drug is in."
descriptionUrl: "https://www.pharmgkb.org/page/downloadDrugsHelp"

Node: dcid:drugCentralSource
name: "drugCentralSource"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: dcs:ChemicalCompoundDiseaseTreatment,dcs:ChemicalCompoundDiseaseContraindication
description: "DrugCentral source for drug-disease relationship."

Node: dcid:drugCourse
name: "drugCourse"
typeOf: schema:Property
rangeIncludes: schema:Quantity
domainIncludes: schema:DrugStrength
description: "Indicates the length of time that drug should be used."

Node: dcid:drugGenericName
name: "drugGenericName"
typeOf: schema:Property
domainIncludes: schema:Drug
rangeIncludes: schema:Text
description: "The name of the generic version of a drug, which is a medication with the exact same active ingredient as the brand-name drug."

Node: dcid:drugHasPrescribingInfo
name: "drugHasPrescribingInfo"
typeOf: schema:Property
domainIncludes: dcs:Drug
rangeIncludes: schema:Boolean
description: "Indicates if there is a prescribing information for a drug."

Node: dcid:drugHasRxAnnotation
name: "drugHasRxAnnotation"
typeOf: schema:Property
domainIncludes: schema:Drug
rangeIncludes: schema:Boolean
description: "The drug has a drug label containing pharmacogenetic information approved by the U.S. Food and Drug Administration (FDA), European Medicines Agencey (EMA), Swiss Agenecy of Therapeutic Products (Swissmedic), Pharmaceuticals and Medical Devices Agency, Japan (PMDA) and/or Health Canada (Sante Canada) (HCSC)."
descriptionUrl: "https://www.pharmgkb.org/labelAnnotations"

Node: dcid:drugLabelAnnotationCount
name: "drugLabelAnnotationCount"
typeOf: schema:Property
domainIncludes: dcs:BiomedicalEntity
rangeIncludes: schema:Number
description: "PharmGKB annotates drug labels approved by the US Food and Drug Administration (FDA) containing pharmacogenetic information. Read more about PharmGKB label annotations, PGx Levels and the "tags" found in the table below. If a specific genetic allele is discussed on the label, it is listed in the "Alleles" column. PharmGKB includes the FDA "PGx Association" group, based on the FDA Table of Pharmacogenetic Associations. This is the number of such labels with which a given drug or genetic variant is associated."

Node: dcid:drugLabelHasDosingInformation
name: "drugLabelHasDosingInformation"
typeOf: schema:Property
domainIncludes: schema:Drug
rangeIncludes: schema:Boolean
description: "The label provides a dose adjustment based on gene/protein/chromosomal variants or phenotypes (e.g. 'poor metabolizers') and does not equivocate on that dose adjustment. The label may also state that a dose adjustment is 'required' or 'should be given'. This tag is not used if the label only states that a dose adjustment 'should be considered'."
descriptionUrl: "https://www.pharmgkb.org/page/drugLabelLegend"

Node: dcid:drugName
name: "drugName"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: schema:Drug

Node: dcid:drugStrength
name: "drugStrength"
typeOf: schema:Property
rangeIncludes: schema:Quantity
rangeIncludes: schema:Text
domainIncludes: schema:DrugStrength
description: "Strength of the drug."

Node: dcid:drugTradeName
name: "drugTradeName"
typeOf: schema:Property
domainIncludes: schema:Drug
rangeIncludes: schema:Text
description: "A standard term in the pharmaceutical industry for a brand name or trademark name of a drug."
descriptionUrl: "https://en.wikipedia.org/wiki/Drug_nomenclature#Drug_brands"

Node: dcid:drugType
name: "drugType"
typeOf: schema:Property
domainIncludes: dcs:ChemicalCompound
rangeIncludes: dcs:DrugTypeEnum
description: "The therapeuatic modality of a drug."

Node: dcid:electronMicroscopyDataBankID
typeOf: schema:Property
name: "electronMicroscopyDataBankID"
rangeIncludes: schema:Text
domainIncludes: dcs:ProteinProteinInteraction
description: "The Electron Microscopy Data Bank (EMDB) identifier."
descriptionUrl: "https://www.ebi.ac.uk/pdbe/emdb/"
abbreviation: "EMDB ID"

Node: dcid:epitope
typeOf: schema:Property
name: "epitope"
description: "Also known as antigenic determinant. It is the recognizing part of an antigen by the interacting immune cell antigen receptor or the antibody."
rangeIncludes: schema:Text
domainIncludes: dcs:Antibody
descriptionUrl:"https://en.wikipedia.org/wiki/Epitope"

Node: dcid:fdaApplicationNumber
name: "fdaApplicationNumber"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: dcs:FDAApplication
description: "The number of the FDA drug application."

Node: dcid:fdaClinicalTrialPhase
name: "fdaClinicalTrialPhase"
typeOf: schema:Property
rangeIncludes: schema:Number
domainIncludes: dcs:ChemicalCompoundDiseaseTreatment
description: "The FDA clinical trial phase for which a compound has been studied to treat the associated disease."

Node: dcid:fdaProductID
name: "fdaProductID"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: schema:DrugStrength
description: "Product ID according to the FDA."

Node: dcid:fdaTopPharmacogeneticLevel
name: "fdaTopPharmacogeneticLevel"
typeOf: schema:Property
domainIncludes: dcs:Drug
rangeIncludes: dcs:PGxLevelEnum
description: "The 'PGx Level' tag ('Testing required', 'Testing Recommended', 'Actionable PGx' and 'Informative PGx') indicates the level of action implied in each label. This is the highest level reported by the Food and Drug Administration (FDA)."
descriptionUrl: "https://www.pharmgkb.org/page/drugLabelLegend"

Node: dcid:finalReconstitutedSolutionVolume
name: "finalReconstitutedSolutionVolume"
typeOf: schema:Property
rangeIncludes: schema:Quantity
domainIncludes: schema:DrugStrength
description: "Final reconstituted solution volume for drug dose."

Node: dcid:geneticVariantAnnotationCount
name: "geneticVariantAnnotationCount"
typeOf: schema:Property
domainIncludes: dcs:BiomedicalEntity
rangeIncludes: schema:Number
description: "Genetic Variant annotations report the association between a variant (e.g. SNP, indel, repeat, haplotype) and a drug phenotype from a single publication. Annotations are created manually by scientific curators who read each paper, extract the key information (including relevant drugs, study size, population data, statistical values, etc.), and map the variants to a common standard (typically dbSNP rsID if it exists). This is the number of such reports associated with a given drug or genetic variant."
descriptionUrl: "https://www.pharmgkb.org/variantAnnotations"

Node: dcid:geneSynonym
name: "geneSynonym"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: dcs:Protein
description: "Synonyms for the gene symbol of gene that codes for a protein."

Node: dcid:ginasID
typeOf: schema:Property
name: "ginasID"
description: "The identifier for substances found in medicines in Ginas. The main goal of ginas is the production of software, called G-SRS, to assist agencies in registering and documenting information about substances found in medicines."
rangeIncludes: schema:Text
domainIncludes: dcs:Antibody
descriptionUrl:"https://tripod.nih.gov/ginas/#/"

Node: dcid:goID
typeOf: schema:Property
name: "goID"
rangeIncludes: schema:Text
domainIncludes: dcs:InteractionDetectionMethodEnum,dcs:InteractionTypeEnum,dcs:InteractionSourceEnum
description: "Identifiers of the Gene Ontology database AmiGO 2."
descriptionUrl: "https://amigo.geneontology.org/amigo/landing"

Node: dcid:hasActiveIngredientAmount
name: "hasActiveIngredientAmount"
typeOf: schema:Property
rangeIncludes: dcs:ActiveIngredientAmount
domainIncludes: schema:DrugStrength
description: "The quantity of active ingredient in the drug."

Node: dcid:hasCpicDosingGuideline
name: "hasCpicDosingGuideline"
typeOf: schema:Property
domainIncludes: dcs:Gene
rangeIncludes: schema:Boolean
description: "The Clinical Pharmacogenetics Implementation Consortium (CPIC) was established in 2009 as a shared project between PharmGKB and the Pharmacogenomics Research Network (PGRN). CPIC is funded by the NIH/NHGRI. This indicates whether a gene has a drug dosing guideline issued by the CPIC that is associated with it."
descriptionUrl: "https://www.pharmgkb.org/page/cpic"

Node: dcid:humanCellType
typeOf: schema:Property
name: "humanCellType"
description: "The human cell type in which the protein's level is measured."
rangeIncludes: dcs:HumanCellTypeEnum
domainIncludes: dcs:HumanProteinOccurrence

Node: dcid:humanProteinOccurrenceReliability
typeOf: schema:Property
name: "humanProteinOccurrenceReliability"
description: "A reliability score is manually set for all genes and indicates the level of reliability of the analyzed protein expression pattern based on available RNA-seq data, protein/gene characterization data and immunohistochemical data from one or several antibodies with non-overlapping epitopes."
descriptionUrl: "https://www.proteinatlas.org/about/assays+annotation#if_reliability_score"
rangeIncludes: dcs:HumanProteinOccurrenceReliabilityEnum
domainIncludes: dcs:HumanProteinOccurrence

Node: dcid:humanTissue
typeOf: schema:Property
name: "humanTissue"
description: "The human tissue in which the protein's level is measured."
rangeIncludes: dcs:HumanTissueEnum
domainIncludes: dcs:HumanProteinOccurrence

Node: dcid:imexID
typeOf: schema:Property
name: "imexID"
rangeIncludes: schema:Text
domainIncludes: dcs:ProteinProteinInteraction
description: "The international molecular exchange consortium identifier for a non-redundant physical molecular interaction."
descriptionUrl: "https://www.imexconsortium.org/"

Node: dcid:imgtMonoclonalAntibodiesDBID
typeOf: schema:Property
name: "imgtMonoclonalAntibodiesDBID"
description: "The identifier for therapeutic monoclonal antibodies in IMGT/mAb-DB. IMGT/mAb-DB is the IMGT monoclonal antibodies (mAb) database."
rangeIncludes: schema:Text
domainIncludes: dcs:Antibody
descriptionUrl:"http://www.imgt.org/mAb-DB/"

Node: dcid:inChIKey
name: "inChIKey"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: dcs:ChemicalCompound
description: "Hash (SHA-256 algorithm) of compound International Union of Applied Chemistry IUPAC International Chemical Identifier. This is a fixed-length format to represent molecules and is derived from InChI."

Node: dcid:intActID
typeOf: schema:Property
name: "intActID"
rangeIncludes: schema:Text
domainIncludes: dcs:ProteinProteinInteraction
description: "EMBL-EBI IntAct identifier."
descriptionUrl: "https://www.ebi.ac.uk/intact/"

Node: dcid:interactingProtein
typeOf: schema:Property
name: "interactingProtein"
description: "A participant protein in a protein-protein interaction."
rangeIncludes: dcs:Protein
domainIncludes: dcs:ProteinProteinInteraction

Node: dcid:interactionDetectionMethod
typeOf: schema:Property
name: "interactionDetectionMethod"
description: "The interaction detection method used in the experiment."
rangeIncludes: dcs:InteractionDetectionMethodEnum
domainIncludes: dcs:ProteinProteinInteraction

Node: dcid:interactionType
typeOf: schema:Property
name: "interactionType"
description: "The molecular interaction type."
rangeIncludes: dcs:InteractionTypeEnum,dcs:ChemicalCompoundProteinInteractionTypeEnum
domainIncludes: dcs:ProteinProteinInteraction,dcs:ChemicalCompoundProteinInteraction

Node: dcid:interactionSource
typeOf: schema:Property
name: "interactionSource"
description: "The database from which the interaction record was extracted."
rangeIncludes: dcs:InteractionSourceEnum
domainIncludes: dcs:ProteinProteinInteraction

Node: dcid:interProID
typeOf: schema:Property
name: "interProID"
description: "The identifier for protein families in Addgene. InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites."
rangeIncludes: schema:Text
domainIncludes: dcs:Antibody
descriptionUrl:"https://www.ebi.ac.uk/interpro/"

Node: dcid:ingredientAmount
name: "ingredientAmount"
typeOf: schema:Property
rangeIncludes: schema:Quantity
rangeIncludes: dcs:QuantityRange
rangeIncludes: schema:Text
domainIncludes: dcs:ActiveIngredientAmount
description: "Amount of the active ingredient."

Node: dcid:ingredientName
name: "ingredientName"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: dcs:ActiveIngredientAmount
description: "Name of the active ingredient."

Node: dcid:isFDAReferenceStandard
name: "isFDAReferenceStandard"
typeOf: schema:Property
rangeIncludes: schema:Boolean
domainIncludes: schema:Drug
description: "Indicates whether the drug is an FDA reference standard."

Node: dcid:isPharmacodynamicRelationship
name: "isPharmacodynamicRelationship"
typeOf: schema:Property
rangeIncludes: schema:Boolean
domainIncludes: dcs:ChemicalCompoundGeneAssociation
description: "True if the pair of entities was found in a pharmacodynamic pathway on PharmGKB, or if the Variant Annotation or Very Important Pharmacogene (VIP) was annotated with Pharmacodynamic (PD) in some manner."
descriptionUrl: "https://www.pharmgkb.org/page/downloadRelationshipsHelp"

Node: dcid:isPharmacokineticRelationship
name: "isPharmacokineticRelationship"
typeOf: schema:Property
rangeIncludes: schema:Boolean
domainIncludes: dcs:ChemicalCompoundGeneAssociation
description: "True if the pair of entities was found in a pharmacokinetic pathway on PharmGKB, or if the Variant Annotation or Very Important Pharmacogene (VIP) was annotated with pharmacokinetic (PK) in some manner."
descriptionUrl: "https://www.pharmgkb.org/page/downloadRelationshipsHelp"

Node: dcid:iupacInternationalChemicalID
name: "iupacInternationalChemicalID"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: dcs:ChemicalCompound
description: "International Union of Applied Chemistry (IUPAC) International Chemical Identifier for compound."

Node: dcid:marketingStatus
name: "marketingStatus"
typeOf: schema:Property
rangeIncludes: dcs:MarketingStatusEnum
domainIncludes: schema:DrugStrength
description: "Marketing status indicates how a drug product is sold in the United States."
descriptionUrl: "https://www.fda.gov/drugs/drug-approvals-and-databases/drugsfda-glossary-terms#M"

Node: dcid:maximumFDAClinicalTrialPhase
name: "maximumFDAClinicalTrialPhase"
typeOf: schema:Property
rangeIncludes: schema:Number
domainIncludes: dcs:ChemicalCompound
description: "The maximum FDA clinical trials phase in which the compound has participated for any disease."

Node: dcid:medicalDictionaryForRegulatoryActivitiesId
name: "medicalDictionaryForRegulatoryActivitiesId"
typeOf: schema:Property
abbreviation: "medraId"
domainIncludes: dcs:ChemicalCompound
rangeIncludes: schema:Text
description: "The identifier for a chemical compound within the Medical Dictionary for Regulatory Activities (MedDRA), which is an internationally used set of terms relating to medical conditions, medicines and medical devices."

Node: dcid:metabolicPathwayCount
name: "metabolicPathwayCount"
typeOf: schema:Property
domainIncludes: dcs:ChemicalCompound
rangeIncludes: schema:Number
description: "The number of PharmGKB pathways associated with a given drug. PharmGKB pathways are evidence-based diagrams depicting the pharmacokinetics (PK) and/or pharmacodynamics (PD) of a drug with relevant (or potential) pharmacogenetic (PGx) associations. Drugs featured in PharmGKB pathways are chosen through extensive review of a variety of sources, including, but not limited to, the U.S. Food and Drug Administration (FDA) biomarker list and Clinical Pharmacogenetics Implementation Consortium (CPIC) nominations."
descriptionUrl: "https://www.pharmgkb.org/pathways"

Node: dcid:mintID
typeOf: schema:Property
name: "mintID"
rangeIncludes: schema:Text
domainIncludes: dcs:ProteinProteinInteraction
description: "Molecular INTeraction database identifier."
descriptionUrl: "https://mint.bio.uniroma2.it/"

Node: dcid:nationalClinicalTrialNumber
name: "nationalClinicalTrialNumber"
typeOf: schema:Property
domainIncludes: schema:Drug
rangeIncludes: schema:Text
sameAs: "https://clinicaltrials.gov/"
description: "The National Clinical Trial (NCT) number is an identification that ClinicalTrials.gov assigns a study when it is registered. The NCT number is in the format 'NCTXXXXXXXX'."

Node: dcid:nationalDrugCode
name: "nationalDrugCode"
typeOf: schema:Property
domainIncludes: schema:Drug
rangeIncludes: schema:Text
sameAs: "https://www.fda.gov/drugs/drug-approvals-and-databases/national-drug-code-directory"
description: "FDA's National Drug Code (NDC) Directory contains information about finished drug products, unfinished drugs and compounded drug products. Drugs are identified in this database by the national drug code."

Node: dcid:nationalDrugFileReferenceTerminologyCode
name: "nationalDrugFileReferenceTerminologyCode"
typeOf: schema:Property
domainIncludes: schema:Drug,dcs:MeSHDescriptor
rangeIncludes: schema:Text
sameAs: "https://nciterms.nci.nih.gov/ncitbrowser/pages/vocabulary.jsf?dictionary=NDFRT"
description: "The code that represents the drug in the National Drug File Reference Terminology (NDF-RT) database. NDF-RT is produced by the Veterans Health Administration (VHA) as an extension of the VHA National Drug File (VANDF) formulary. It organizes the drug list into a formal representation. NDF-RT is used for modeling drug characteristics including ingredients, chemical structure, dose form, physiologic effect, mechanism of action, pharmacokinetics, and related diseases. NDF-RT is part of the Federal Medication Terminologies (FMT), and three components -- Mechanism of Action, Physiologic Effect, and Structural Class - are used in FDA Structured Product Labeling (SPL)."

Node: dcid:neuroMabID
typeOf: schema:Property
name: "neuroMabID"
description: "The identifier for mouse monoclonal antibodies in NeuroMab. The UC Davis/NIH NeuroMab Facility generates mouse monoclonal antibodies extensively validated for use in the mammalian brain."
rangeIncludes: schema:Text
domainIncludes: dcs:Antibody
descriptionUrl:"https://neuromab.ucdavis.edu"

Node: dcid:patentID
typeOf: schema:Property
name: "patentID"
description: "The identifier of patent in PATENTSCOPE. Using PATENTSCOPE you can search 90 million patent documents including 3.9 million published international patent applications (PCT)."
rangeIncludes: schema:Text
domainIncludes: dcs:Antibody
descriptionUrl:"https://patentscope.wipo.int/search/en/search.jsf"

Node: dcid:pharmacogeneticAssociation
name: "pharmacogeneticAssociation"
typeOf: schema:Property
domainIncludes: dcs:Drug
rangeIncludes: dcs:PharmacogeneticAssociationEnum
description: "These associaitons are based off of the FDA Table of Pharmacogenetic Associations."

Node: dcid:pharmGkbRareVariantScoringRange
name: "pharmGkbRareVariantScoringRange"
typeOf: schema:Property
domainIncludes: dcs:PharmGkbClinicalLevelEnum
rangeIncludes: schema:Text
description: "The assignment of clinical annotation levels of evidence (LOE) is primarily informed by the PharmGKB annotation scoring system for clinical annotations and variant annotations. This reports the scoring range that determines the level for rare genetic variants defined as having a minor allele frequenct (MAF) <0.01 or <1%."
descriptionUrl: "https://www.pharmgkb.org/page/clinAnnLevels"

Node: dcid:prositeID
typeOf: schema:Property
name: "prositeID"
description: "The identifier in PROSITE database. PROSITE consists of documentation entries describing protein domains, families and functional sites as well as associated patterns and profiles to identify them."
rangeIncludes: schema:Text
domainIncludes: dcs:Antibody
descriptionUrl:"https://prosite.expasy.org/index.html"

Node: dcid:proteinDataBankID
name: "proteinDataBankID"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: dcs:Protein,dcs:ChemicalCompound
description: "Protein Data Bank identifier of a protein."

Node: dcid:proteinDataBankInEuropeID
typeOf: schema:Property
name: "proteinDataBankInEuropeID"
rangeIncludes: schema:Text
domainIncludes: dcs:ProteinProteinInteraction
description: "EMBL-EBI Protein Data Bank in Europe (PDBe) identifier."
descriptionUrl: "https://www.ebi.ac.uk/pdbe/node/1"

Node: dcid:proteinExpressionScore
typeOf: schema:Property
name: "proteinExpressionScore"
description: "Protein expression score is based on immunohistochemical data manually scored with regard to staining intensity (negative, weak, moderate or strong) and fraction of stained cells (<25%, 25-75% or >75%)."
descriptionUrl: "https://www.proteinatlas.org/about/help#4"
rangeIncludes: dcs:ProteinExpressionScoreEnum
domainIncludes: dcs:HumanProteinOccurrence

Node: dcid:proteinID
name: "proteinID"
typeOf: schema:Property
rangeIncludes: dcs:Protein
domainIncludes: dcs:ChemicalCompoundProteinInteraction,dcs:ProteinProteinInteraction
description: "The Protein node associated with the current node."

Node: dcid:psimiID
typeOf: schema:Property
name: "psimiID"
rangeIncludes: schema:Text
domainIncludes: dcs:ProteinProteinInteraction,dcs:InteractionTypeEnum,dcs:InteractionDetectionMethodEnum,dcs:InteractionSourceEnum
description: "Proteomics Standard Initiative - Molecular Interaction identifier."
descriptionUrl: "https://www.psidev.info"

Node: dcid:pubMedID
typeOf: schema:Property
name: "pubMedID"
rangeIncludes: schema:Text
domainIncludes: dcs:BiomedicalEntity
description: "Identifier for reference paper on PubMed."
descriptionUrl: "https://pubmed.ncbi.nlm.nih.gov/"

Node: dcid:reactomePathwayID
typeOf: schema:Property
name: "reactomePathwayID"
rangeIncludes: schema:Text
domainIncludes: dcs:ProteinProteinInteraction
description: "Reactome identifier. Reactome is a free, open-source, curated and peer-reviewed pathway database."
descriptionUrl: "https://reactome.org/"

Node: dcid:rcsbPDBID
typeOf: schema:Property
name: "rcsbPDBID"
rangeIncludes: schema:Text
domainIncludes: dcs:ProteinProteinInteraction
description: "Research Collaboratory for Structural Bioinformatics (RCSB) Protein Data Bank (PDB) identifier."
descriptionUrl: "https://www.rcsb.org/"

Node: dcid:recognizesAntigen
typeOf: schema:Property
name: "recognizesAntigen"
description: "The targeting antigen of the antibody."
rangeIncludes: dcs:Protein
domainIncludes: dcs:Antibody
# rangeIncludes proteins with links to UniProt, chemicals with IDs to ChEBI and a few samples to other databases (InterPro, NCBI, Prosite, UniProt-Subcell).

Node: dcid:recombinantAntibodyNetworkID
typeOf: schema:Property
name: "recombinantAntibodyNetworkID"
description: "The identifier for antibodies in Recombinant Antibody Network (RAN). The RAN is an international consortium of three expert centers at the University of Chicago, University of Toronto, and the University of California at San Francisco (UCSF) unified under a common set of goals, technologies, and operational procedures."
rangeIncludes: schema:Text
domainIncludes: dcs:Antibody
descriptionUrl:"https://recombinant-antibodies.org/"

Node: dcid:relationshipAssociationType
name: "relationshipAssociationType"
typeOf: schema:Property
rangeIncludes: dcs:RelationshipAssociationTypeEnum
domainIncludes: dcs:ChemicalCompoundGeneAssociation
description: "Extent of relationship association between entities as defined by PharmGKB, either 'associated', 'ambiguous', or 'not associated'."

Node: dcid:relationshipEvidenceType
name: "relationshipEvidenceType"
typeOf: schema:Property
rangeIncludes: dcs:RelationshipEvidenceTypeEnum
domainIncludes: dcs:ChemicalCompoundGeneAssociation
description: "Type of evidence supporting a given relationship between entities."

Node: dcid:residID
typeOf: schema:Property
name: "residID"
rangeIncludes: schema:Text
domainIncludes: dcs:InteractionDetectionMethodEnum,dcs:InteractionTypeEnum,dcs:InteractionSourceEnum
description: "Identifiers of the RESID database which contains the collections of annotations and structures for protein modifications."
descriptionUrl: "https://proteininformationresource.org/resid/"

Node: dcid:rxConceptUniqueId
name: "rxConceptUniqueId"
typeOf: schema:Property
abbreviation: "rxCUI"
domainIncludes: dcs:ChemicalCompound
rangeIncludes: schema:Text
description: "RxNorm is two things: a normalized naming system for generic and branded drugs; and a tool for supporting semantic interoperation between drug terminologies and pharmacy knowledge base systems. The National Library of Medicine (NLM) produces RxNorm. This is the Concept Unique Identifier for a concept in RxNorm."
descriptionUrl: "https://www.nlm.nih.gov/research/umls/rxnorm/overview.html"

Node: dcid:rxNormId
name: "rxNormId"
typeOf: schema:Property
domainIncludes: schema:Drug
rangeIncludes: schema:Number
sameAs: "https://www.nlm.nih.gov/research/umls/rxnorm/index.html"
description: "The identifier for this drug in the NIH National Library of Science RxNorm database, which is apart of the Unified Medical Language System (UMLS). RxNorm provides normalized names for clinical drugs and links its names to many of the drug vocabularies commonly used in pharmacy management and drug interaction software, including those of First Databank, Micromedex, Multum, and Gold Standard Drug Database. By providing links between these vocabularies, RxNorm can mediate messages between systems not using the same software and vocabulary."

Node: dcid:simplifiedMolecularInputLineEntrySystem
name: "simplifiedMolecularInputLineEntrySystem"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: dcs:ChemicalCompound
description: "Simplified Molecular-Input Line-Entry System (SMILES) for compound."

Node: dcid:singleDose
name: "singleDose"
typeOf: schema:Property
rangeIncludes: schema:Boolean
domainIncludes: schema:DrugStrength
description: "Indicates whether the drug is to be taken as a single dose (True) or as multiple doses (False)."

Node: dcid:submittedFDAApplication
name: "submittedFDAApplication"
typeOf: schema:Property
rangeIncludes: dcs:FDAApplication
domainIncludes: schema:DrugStrength
description: "The application submitted to the FDA for this drug."

Node: dcid:swissProtID
name: "swissProtID"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: dcs:Protein
description: "Identifier referring to a protein in the Swiss-Prot database. A manually curated database with records with information extracted from literature and curator-evaluated computational analysis."

Node: dcid:therapeuticEquivalenceCode
name: "therapeuticEquivalenceCode"
typeOf: schema:Property
rangeIncludes: dcs:TherapeuticEquivalenceCodeEnum
domainIncludes: schema:DrugStrength
description: "The therapeutic equivalence code indicates whether the FDA has evaluated a particular approved product (e.g., a particular strength of an approved drug) as therapeutically equivalent to other pharmaceutically equivalent products and to provide additional information on the basis of FDA's evaluations (second letter)."
descriptionUrl: "https://www.fda.gov/drugs/development-approval-process-drugs/orange-book-preface#TEC"

Node: dcid:topClinicalAnnotationLevel
name: "topClinicalAnnotationLevel"
typeOf: schema:Property
domainIncludes: dcs:ChemicalCompound
rangeIncludes: dcs:PharmGkbClinicalLevelEnum
description: "PharmGKB clinical annotations provide information about variant-drug pairs based on variant annotations and incorporating variant-specific prescribing guidance from clinical guidelines and FDA approved drug labels, when available. PharmGKB scientific curators manually review variant annotations and create genotype-based summaries describing the phenotypic impact of the variant. The clinical annotation is given a score, based on the scores of the supporting annotations. A clinical annotation's score is used by PharmGKB curators in the process of assigning a Level of Evidence to the annotation. Levels range from 1-4, with level 1 meeting the highest criteria. The highest level of clinical annotation of any variant associated with a drug is reported here."
descriptionUrl: "https://www.pharmgkb.org/clinicalAnnotations"

Node: dcid:topCpicLevel
name: "topCpicLevel"
typeOf: schema:Property
domainIncludes: dcs:Drug
rangeIncludes: dcs:CPICLevelEnum
description: "The Clinical Pharmacogenetics Implementation Consortium (CPIC) assigns CPIC levels to gene/drug pairs. The levels (A, B, C, and D) assigned are subject to change; only those gene/drug pairs that have been the subject of guidelines have had sufficient in-depth review of evidence to provide definitive CPIC level assignments. Note that only CPIC level A and B gene/drug pairs have sufficient evidence for at least one prescribing action to be recommended. CPIC level C and D gene/drug pairs are not considered to have adequate evidence or actionability to have prescribing recommendations."
descriptionUrl: "https://cpicpgx.org/prioritization/"

Node: dcid:topPharmacogeneticLevel
name: "topPharmacogeneticLevel"
typeOf: schema:Property
domainIncludes: dcs:Drug
rangeIncludes: dcs:PGxLevelEnum
description: "The 'PGx Level' tag ('Testing required', 'Testing Recommended', 'Actionable PGx' and 'Informative PGx') indicates the level of action implied in each label. This is the highest level reported by any reporting agency."
descriptionUrl: "https://www.pharmgkb.org/page/drugLabelLegend"

Node: dcid:uniProtID
name: "uniProtID"
typeOf: schema:Property
rangeIncludes: schema:Text
domainIncludes: dcs:Protein,dcs:ChemicalCompoundProteinInteraction,dcs:ChemicalCompound,dcs:Gene
description: "UniProt identifier of protein."
Node: dcid:uniProtSubcellularID
typeOf: schema:Property

name: "uniProtSubcellularID"
description: "The identifier of subcellular locations in UniProt. The subcellular locations in which a protein is found are described in UniProtKB entries with a controlled vocabulary, which also includes membrane topology and orientation terms."
rangeIncludes: schema:Text
domainIncludes: dcs:Antibody
descriptionUrl:"https://www.uniprot.org/locations/"

Node: dcid:variantID
typeOf: schema:Property
domainIncludes: dcs:ChemicalCompoundGeneticVariantAssociation,dcs:GeneGeneticVariantAssociation
rangeIncludes: dcs:GeneticVariant
description: "Link to a GeneticVariant node for a genetic variant that is associated with another entity."

Node: dcid:veryImportantPharmacogeneCount
name: "veryImportantPharmacogeneCount"
typeOf: schema:Property
domainIncludes: dcs:ChemicalCompound
rangeIncludes: schema:Number
description: "The number of Very Important Pharmacogene (VIP) summaries assocated with a given drug as reported by PharmGKB. VIP summaries provide an overview of a significant gene involved in metabolism of, or response to, one or several drugs. Often, VIPs either play a role in the metabolism of many drugs (e.g. CYP2D6), or contain variants which potentially contribute to a severe drug response (e.g. HLA-B). VIP summaries typically include background information on the gene including any disease associations, as well as in-depth information on the gene's pharmacogenetics. Many VIP summaries have been published in the journal Pharmacogenetics and Genomics."
descriptionUrl: "https://www.pharmgkb.org/vips"

Node: dcid:wordElementType
name: "wordElementType"
typeOf: schema:Property
domainIncludes: dcs:USAdoptedNameStem
rangeIncludes: dcs:WordElementTypeEnum
description: "A word's elements are the smallest parts that add meaning to the word."

Node: dcid:worldWideProteinDataBankID
typeOf: schema:Property
name: "worldWideProteinDataBankID"
rangeIncludes: schema:Text
domainIncludes: dcs:ProteinProteinInteraction
description: "The Worldwide Protein Data Bank (wwPDB) identifier, which serves as the single repository of information about the 3D structures of proteins, nucleic acids, and complex assemblies."
descriptionUrl: "https://www.ebi.ac.uk/pdbe/", "https://www.rcsb.org/", "https://pdbj.org/", "http://www.bmrb.wisc.edu/".
abbreviation: "wwPDB ID"