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Data analyses related to Truth Density bias in commonly used Boolean Regulatory Functions

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druglogics/brf-bias

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brf-bias

DOI

Data analyses related to the paper:

Zobolas, J., Monteiro, P. T., Kuiper, M., & Flobak, Å. (2022). Boolean function metrics can assist modelers to check and choose logical rules. Journal of Theoretical Biology, 538, 111025. https://doi.org/10.1016/J.JTBI.2022.111025

See the full report here.

Note

Various results, conclusions and proofs from the report have been extensively refined and rewritten in the paper, so better to consult the paper on these.

The code for the figures, data availability and software details to generate and analyze the studied Boolean models are mentioned in the report.

Links

Some links to analyses mentioned in the paper are provided below:

  • Link 1: CASCADE 1.0 network properties (degree distribution, etc.)
  • Link 2: Correlation analysis between average node state and parameterization-state agreement in the CASCADE 1.0 models