MANUSCRIPT TITLE
Pancreatic cancer is associated with medication changes prior to clinical diagnosis


DATA ANALYSIS
Data analyses were performed using SAS statistical software, version 9.4 for UNIX (SAS Institute Inc., Cary, NC). 


DATA AVAILABILITY
Data described in the manuscript are available upon formal application to and approval by the Channing Division of Network Medicine at Brigham and Women’s Hospital, and Harvard T.H. Chan School of Public Health. To ensure the confidentiality and privacy of cohort participants, written request for access to the data is required. The standard procedure for controlled access requires that applications to use the resources of the Nurses' Health Studies and Health Professionals Follow-up Study undergo a formal review by the cohort committee. The committee assesses the scientific aims, examines the suitability of the proposed methodology for the available data, and confirms that the proposed use aligns with the guidelines of the Ethics and Governance Framework. Further information including the procedures to obtain and access data from the Nurses’ Health Study and Health Professionals Follow-Up Study is described at https://www.nurseshealthstudy.org/researchers (email: nhsaccess@channing.harvard.edu) and https://sites.sph.harvard.edu/hpfs/for-collaborators/.


LIST OF SAS CODE
Table 1 and Supplementary Tables 1-11:
T1_ST1_2_4_6_8_antidb.sas
T1_ST1_2_4_6_8_10_antico.sas
T1_ST1_2_4_6_8_10_antihp.sas
T1_ST1_3_5_7_9_11_antacid.sas 
T1_ST1_3_5_7_9_11_nsaid.sas
T1_ST1_3_5_7_9_11_antidep.sas
Table 2:
T2_combine.sas
Figure 2 and Supplementary Table 12: 
F2_ST12_combo.sas
Figure 3 and Supplementary Table 13:
F3_ST13_antidb.sas
F3_ST13_antico.sas
F3_ST13_antihp.sas


EXPECTED TOTAL RUN TIME ON COMPUTING CLUSTER
12-24h


SYSTEM REQUIREMENTS
Computing cluster using UNIX system
SAS statistical software, version 9.4 for UNIX


INSTALLATION GUIDE
Please see details at 
https://www.sas.com/en_us/software/stat.html (for SAS)
and 
https://unix.org/ (for UNIX)


INSTRUCTION FOR USE
Please see details at 
https://www.sas.com/en_us/software/stat.html (for SAS)
and 
https://unix.org/ (for UNIX)