diff --git a/lib/galaxy/webapps/galaxy/script.py b/lib/galaxy/webapps/galaxy/script.py
new file mode 100644
index 000000000000..59708d945924
--- /dev/null
+++ b/lib/galaxy/webapps/galaxy/script.py
@@ -0,0 +1,30 @@
+import os
+from argparse import ArgumentParser
+
+import uvicorn
+
+
+def main() -> None:
+    parser = ArgumentParser(
+        prog="galaxy-web",
+        description="Run Galaxy Web Server",
+    )
+    parser.add_argument("--config", "-c", help="Galaxy config file")
+    parser.add_argument("--single-user", "-s", help="Single user mode as user SINGLE_USER")
+    parser.add_argument("--bind", "-b", default="localhost:8080", help="Bind to <host>:<port>")
+    parser.add_argument(
+        "--client-path", "-n", default="node_modules/@galaxyproject/galaxy-client", help="Path to Galaxy client"
+    )
+    args = parser.parse_args()
+    env = os.environ.copy()
+    if args.config:
+        env["GALAXY_CONFIG_FILE"] = args.config
+    if args.single_user:
+        env["GALAXY_CONFIG_SINGLE_USER"] = args.single_user
+        env["GALAXY_CONFIG_ADMIN_USERS"] = args.single_user
+    uvicorn.run(
+        "galaxy.webapps.galaxy.fast_factory:factory",
+        factory=True,
+        host=args.bind.split(":")[0],
+        port=int(args.bind.split(":")[1]),
+    )
diff --git a/packages/web_apps/setup.cfg b/packages/web_apps/setup.cfg
index 914d43a895d2..bcf88a282c43 100644
--- a/packages/web_apps/setup.cfg
+++ b/packages/web_apps/setup.cfg
@@ -68,6 +68,10 @@ install_requires =
 packages = find:
 python_requires = >=3.8
 
+[options.entry_points]
+console_scripts =
+        galaxy-web = galaxy.webapps.galaxy.script:main
+
 [options.packages.find]
 exclude =
     tests*