Python 3 Dependencies: csv, argparse, cairosvg This program is a little memory hungry... Note: Current version uses the GRCh37 (hg19) genome. If a different species or genome build is desired, the "chromosome_sizes" list can be adjusted in the python skript. A bar with ploidies will be plotted on the right side of the heatmap. Usage: -o Output filename -c node_unmerged_cnv_calls.bed file from the 10x pipeline output -p per_cell_summary_metrics.csv file from the 10x pipeline output Optional: -e Set to "no" to include noisy cells marked by the 10x pipeline. Default is "yes" -f Set a lower ploidy cuttoff if desired. E.g "-f 1.1" will exclude all cells with a ploidy lower than 1.1
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Generates meaninful heatmaps from 10x single cell CNV data
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