04_Molecular.ipynb

{
 "cells": [
  {
   "cell_type": "markdown",
   "id": "bb14bf30-d734-4bc5-9097-5dc78652632b",
   "metadata": {
    "tags": []
   },
   "source": [
    "# Molecular Entities (Genes / Proteins, Variants) in GGPONC"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "70f0f1f6",
   "metadata": {},
   "source": [
    "## Prepare Custom Tokenization Rules"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 1,
   "id": "0c2ed77a",
   "metadata": {
    "tags": []
   },
   "outputs": [],
   "source": [
    "import spacy\n",
    "\n",
    "nlp = spacy.load('de_dep_news_trf')\n",
    "# Make sure compounds (\"BRAF-Mutation\") are tokenized\n",
    "infixes = nlp.Defaults.infixes + [r'([-+/–\\(\\)])']\n",
    "nlp.tokenizer.infix_finditer = spacy.util.compile_infix_regex(infixes).finditer"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 2,
   "id": "3c25e072",
   "metadata": {
    "tags": []
   },
   "outputs": [],
   "source": [
    "# Store for training NER model using the same tokenizer\n",
    "nlp.to_disk(\"spacy_ner/molecular_tokenizer\")"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "8dd03145-2b78-44c8-a183-5a96d99335ef",
   "metadata": {
    "tags": []
   },
   "source": [
    "## Model Training\n",
    "\n",
    "Place the contents of `molecular_2024_04_03` into the `data` folder, then run:\n",
    "\n",
    "- `cd spacy_ner`\n",
    "- `./run_training.sh <CUDA DEVICE> ../data/molecular_2024_04_03 GerMedBERT/medbert-512 spancat_molecular`"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "4a0a83c3-1885-41af-bb43-9438990b5024",
   "metadata": {},
   "source": [
    "# Load Dataset"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "id": "87b3aae9-1a12-487b-84ab-0e7ec0a99720",
   "metadata": {
    "tags": []
   },
   "outputs": [],
   "source": [
    "from pathlib import Path\n",
    "data_path = Path('data/molecular_2024_04_03/')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 4,
   "id": "56ac5ff4-bd41-4fe7-ad1a-b4afd9ae1a23",
   "metadata": {
    "tags": []
   },
   "outputs": [],
   "source": [
    "SPLITS = ['train', 'validation', 'test']"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 5,
   "id": "2221f3cc-6a18-44e5-b011-ef439f985aee",
   "metadata": {
    "tags": []
   },
   "outputs": [],
   "source": [
    "from xmen.data import from_spacy\n",
    "from spacy.tokens import DocBin\n",
    "\n",
    "docs = {}\n",
    "\n",
    "for split in SPLITS:\n",
    "    db = DocBin(store_user_data=True).from_disk(data_path / f'{split}.spacy')\n",
    "    docs[split] = list(db.get_docs(nlp.vocab))"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 6,
   "id": "1dfae7c6-94be-47de-855a-e14c7415a8f1",
   "metadata": {
    "tags": []
   },
   "outputs": [],
   "source": [
    "all_docs = sum(docs.values(), [])"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 7,
   "id": "b8bb963e-32c8-4b6b-9e3a-2a5660df92cf",
   "metadata": {
    "tags": []
   },
   "outputs": [],
   "source": [
    "def get_genes(docs):\n",
    "    return [e.text for d in docs for e in d.spans['entities'] if e.label_ == 'Gene or Protein']\n",
    "\n",
    "def get_variants(docs):\n",
    "    return [e.text for d in docs for e in d.spans['entities'] if e.label_ == 'Variant']"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 8,
   "id": "c5cbb820-022e-4181-9c7d-468b74ca2d15",
   "metadata": {
    "tags": []
   },
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "train Docs 239 #Genes 1766 #Variants 633\n",
      "validation Docs 52 #Genes 407 #Variants 110\n",
      "test Docs 52 #Genes 377 #Variants 106\n",
      "Total Docs 343 #Genes 2550 #Variants 849\n"
     ]
    }
   ],
   "source": [
    "for split in SPLITS:\n",
    "    d = docs[split]\n",
    "    print(split, 'Docs', len(d), '#Genes', len(get_genes(d)), '#Variants', len(get_variants(d)))\n",
    "print('Total', 'Docs', len(all_docs), '#Genes', len(get_genes(all_docs)), '#Variants', len(get_variants(all_docs)))"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "f6e3d8e5-1b83-48eb-8208-4baca563e02d",
   "metadata": {},
   "source": [
    "## Types / Unique Names"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 9,
   "id": "12cbd02f-3c9b-43f4-b0e3-234a18aa33fe",
   "metadata": {
    "tags": []
   },
   "outputs": [
    {
     "data": {
      "text/plain": [
       "<matplotlib_venn._common.VennDiagram at 0x7fc9c9a379d0>"
      ]
     },
     "execution_count": 9,
     "metadata": {},
     "output_type": "execute_result"
    },
    {
     "data": {
      "image/png": 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",
      "text/plain": [
       "<Figure size 640x480 with 1 Axes>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "from matplotlib_venn import venn3\n",
    "\n",
    "train_genes = set(get_genes(docs['train']))\n",
    "val_genes = set(get_genes(docs['validation']))\n",
    "test_genes = set(get_genes(docs['test']))\n",
    "\n",
    "venn3([train_genes, val_genes, test_genes], ['Train (Genes)', 'Validation (Genes)', 'Test (Genes)'])"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 10,
   "id": "440c152e-9cd4-4be9-8cb4-97268929d62c",
   "metadata": {
    "tags": []
   },
   "outputs": [
    {
     "data": {
      "text/plain": [
       "<matplotlib_venn._common.VennDiagram at 0x7fc9c9902a10>"
      ]
     },
     "execution_count": 10,
     "metadata": {},
     "output_type": "execute_result"
    },
    {
     "data": {
      "image/png": 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a6mw2YMsWhh6ijnA65bFw5eVKV0JEIYbBJ5TV1QHvvQdUVSldCVH4aZgIUF2tdCVEFEIYfEJVfb3c0lNTo3QlROHLbpcnBNTVKV0JEYUIBp9Q5HIBH3wA1NYqXQlR+Kurk1t+HA6lKyGiEMDgE2q8XnmzUc7eIgqcqio5/LhcSldCRApj8Ak1O3YAZ84oXQVR5Ckrk1c893iUroSIFMTgE0p27eLeW0TBVFIit6iKotKVEJFCGHxCxb//Dezfr3QVRJHv1Cng00+VroKIFMLgEwqOHgV27lS6CiL1OHIE2LdP6SqISAEMPkorKZF/++QC2kRda/du4MQJpasgoi7G4KOkmhqgoECeyUVEXUuSgE8+4QKhRCrD4KMUjwcoLJSX1iciZbhc8mBnTnMnUg0GH6V8+SX3ESIKBVVVcssPu5uJVIHBRwmHDsk3IgoNJ04Ae/YoXQURdQEGn65WXi639hBRaPn2W3mGJRFFNAafruRyyeN6uHIsUWjasYPbxRBFOAafrvTZZ9xtnSiUeTzyeB+u7EwUsRh8usr+/UBxsdJVEFFbKirkNX6IKCIx+HSFc+eAb75Rugoiaq/9+4GzZ5WugoiCgMEn2DweeWVmNp0ThQ9Jkr9vub4PUcRh8Am2PXs4rocoHNXVAV99pXQVRBRgDD7BVFoKHDigdBVE5K+ffuLYvC5w7NgxCIKAV199tfG+pUuXQhCEdj1fEAQsXbo0oDXl5+cjPz8/oOfsiPXr1yMhIQF1dXWKXF/p19+W7du3w2q14vz58x1+LoNPsHi98tRYrgZLFN4+/xyw2ZSuImRMnToVFosFtbW1rR4za9YsGAwGlIf46vQ//PADli5dimPHjildig+v14tHH30U9913H6xWK/bu3QtBEPDII4+0+pzDhw9DEAQ88MADXVhp52zbts3vwDpx4kT06dMHTzzxRIefy+ATLEVF3PyQKBI4HPJSFARADjV2ux3vvPNOi4/bbDZs3rwZEydORGJiot/XeeSRR2C32/1+fnv88MMPeOyxx1oMPh9++CE+/PDDoF6/NVu2bMGhQ4fwu9/9DgAwdOhQDBgwAG+++Warz1m7di0AYPbs2QGpoSte/7Zt2/DYY4/5/fz58+dj1apVFw3hLWHwCYayMnlWCBFFhpMnuc3M/5k6dSqio6Mbf9BeaPPmzaivr8esWbM6dR2dTgeTydSpc3SGwWCAwWBQ5NqvvPIKrrzySnTr1q3xvlmzZuHo0aPYtWtXi8958803MWDAAAwdOrRT17b9X+umkq+/vW644QY4nU5s2LChQ89j8Ak0UZS7uDiLiyiyfP01Z3kBMJvNmDFjBj7++GOUlpY2e3zt2rWIjo7G1KlTUVFRgT/+8Y8YPHgwrFYrYmJiMGnSJHz33XdtXqelMT5OpxN/+MMfkJyc3HiNU6dONXvu8ePHsWDBAvTv3x9msxmJiYm46aabfFp2Xn31Vdx0000AgF//+tcQBAGCIGDHjh0AWh7jUlpaijvuuAOpqakwmUy49NJLsXr1ap9jGsYr/e1vf8OLL76I7OxsGI1GXH755djdjvWhHA4Htm/fjquvvtrn/oYg2VLgLCoqwqFDhxqP2bx5MyZPnoyMjAwYjUZkZ2fj8ccfh9fr9Xlefn4+Bg0ahKKiIowePRoWiwUPP/xwi6/f5XJhyZIlyMvLQ2xsLKKiojBq1Ch8+umnfr3+uXPnYvny5QDQ+N43/fd+6623kJeXh+joaMTExGDw4MF49tlnfa6VkpKC3NxcbN68uc33tSldh46mtn37LZe8J4pEDoe8sOGVVypdieJmzZqF1atXY/369bj33nsb76+oqEBBQQFmzpwJs9mM77//Hu+++y5uuukmZGZm4ty5c1i1ahXGjBmDH374ARkZGR267p133ok1a9bgtttuw8iRI/HJJ59g8uTJzY7bvXs3vvrqK9x6663o3r07jh07hpUrVyI/Px8//PADLBYLRo8ejUWLFuG5557Dww8/jIEDBwJA458XstvtyM/Px88//4x7770XmZmZ2LBhA+bOnYuqqircf//9PsevXbsWtbW1mD9/PgRBwF//+lfMmDEDR48ehV6vb/U1FhUVweVyNWu5yczMxMiRI7F+/Xo8/fTT0Gq1PtcCgNtuuw2AHOqsViseeOABWK1WfPLJJ1iyZAlqamrw1FNP+Zy3vLwckyZNwq233orZs2cjNTW1xbpqamrw0ksvYebMmbjrrrtQW1uLl19+GRMmTMA333yDIUOGdOj1z58/H2fOnEFhYSFef/11n+cWFhZi5syZGDduHJ588kkAwMGDB/Hll182e5/z8vLw7rvvtvp+toTBJ5AqK+XgQ0SR6YcfgIEDgYQEpStR1NixY5Geno61a9f6BJ8NGzbA7XY3tjwMHjwYP/30EzSaXzoXfvOb32DAgAF4+eWXsXjx4nZf87vvvsOaNWuwYMGCxpaChQsXYtasWdh/wdCCyZMn48Ybb/S577rrrsOIESPw9ttv4ze/+Q2ysrIwatQoPPfcc7jmmmvanMH04osv4uDBg1izZk3j67v77rsxZswYPPLII5g3bx6io6Mbjz9x4gQOHz6M+Ph4AED//v0xbdo0FBQUYMqUKa1e58cffwQgB50LzZo1CwsXLsTHH3+M8ePHAwBEUcS6deswYsQIZGVlAZBDh9lsbnze3XffjbvvvhsrVqzAf/3Xf8FoNDY+VlJSghdeeAHz58+/6OuPj4/HsWPHfLq/7rrrLgwYMADPP/88Xn75ZZ/j23r9I0aMQL9+/VBYWNhsXNL777+PmJgYFBQU+AS8lmRlZaGsrAylpaVISUm56LEN2NUVSLt2sYuLKJJJEvDFF0pXoTitVotbb70VO3fu9Ok+Wrt2LVJTUzFu3DgAgNFobAw9Xq8X5eXlsFqt6N+/P/bu3duha27btg0AsGjRIp/7f//73zc7tukPfbfbjfLycvTp0wdxcXEdvm7T66elpWHmzJmN9+n1eixatAh1dXX47IIB8LfcckvjD30AGDVqFADg6NGjF71Ow0y4ps9tek69Xu/T3fXZZ5/h9OnTPmOqmr7+2tpalJWVYdSoUbDZbI3BqoHRaMTtt99+0ZoA+d+8IfSIooiKigp4PB4MGzasxffU39cPAHFxcaivr0dhYWGbxzZco6ysrM1jGzD4BMqpU/IASCKKbCUlwM8/K12F4i4cc3Lq1Cl8/vnnuPXWWxt/SxdFEU8//TT69u0Lo9GIpKQkJCcnY//+/aiuru7Q9Y4fPw6NRoPs7Gyf+/v379/sWLvdjiVLlqBHjx4+162qqurwdZtev2/fvj6tV8AvXWPHjx/3ub9nz54+Xzf8gK6srGzX9aQWlkJJTEzEhAkT8M4778DhcACQ33+dToebb7658bjvv/8e06dPR2xsLGJiYpCcnNzYqnLh6+/WrVu7BzGvXr0aubm5MJlMSExMRHJyMt5///0W39POvP4FCxagX79+mDRpErp374558+Zh+/btLR7b8D61d80ngMEnMCRJbu0hInXYtQtwu5WuQlF5eXk+U6zffPNNSJLk0/Lwl7/8BQ888ABGjx6NNWvWoKCgAIWFhbjkkksgBrF1/L777sOf//xn3HzzzVi/fj0+/PBDFBYWIjExMajXbaq1LpqWAk1TDUsAtBYQZs+ejZqaGmzduhUulwtvv/02xo8fj+TkZABAVVUVxowZg++++w7Lli3Dli1bUFhY2DhW5sLX37R16GLWrFmDuXPnIjs7Gy+//DK2b9+OwsJCjB07tsX31N/XD8iDlvft24f33nsPU6dOxaeffopJkyZhzpw5zY5teJ+SkpLa9ToAjvEJjEOHOKCZSE1sNnmtruHDla5EUbNmzcLixYuxf/9+rF27Fn379sXll1/e+PjGjRvx61//utn4j6qqqg79oAKAXr16QRRFHDlyxKeV51ALywxs3LgRc+bMwd///vfG+xwOB6ouWFutI60EvXr1wv79+yGKok+rT0PXUa9evdp9rosZMGAAAKC4uBiDBw9u9njT5QT0ej0qKyt9wuaOHTtQXl6OTZs2YfTo0Y33F3dyBfKNGzciKysLmzZt8nnfHn30Ub/PebH332Aw4LrrrsN1110HURSxYMECrFq1CosXL0afPn0ajysuLm5s0Wsvtvh0ltst78dFROry73+rfpHShh+4S5Yswb59+5qt3aPVapv9hr9hwwacPn26w9eaNGkSAOC5557zuf+ZZ55pdmxL133++eebTeeOiooCgGaBqCXXXnstSkpKsG7dusb7PB4Pnn/+eVitVowZM6Y9L6NNeXl5MBgM2NPKzxWz2Yzp06dj27ZtWLlyJaKiojBt2rTGxxtaWpq+fpfLhRUrVnSqrpbO+/XXX2Pnzp1+n7O19//CFb81Gg1yc3MByEsaNFVUVIQRI0Z06Lps8ems777jcvZEaiSKwM6dwP/9QA7qpSQRoiRCpwmtj+yGKdYN66hcGHymTJmCZcuW4fbbb8fIkSNx4MABvPHGG42zjzpiyJAhmDlzJlasWIHq6mqMHDkSH3/8MX5uYbzVlClT8PrrryM2NhY5OTnYuXMnPvroo2YrSQ8ZMgRarRZPPvkkqqurYTQaMXbs2BZnB/3ud7/DqlWrMHfuXBQVFaF3797YuHEjvvzySzzzzDM+M7o6w2QyYfz48fjoo4+wbNmyFo+ZPXs2XnvtNRQUFGDWrFmNAQIARo4cifj4eMyZMweLFi2CIAh4/fXX29XFdDFTpkzBpk2bMH36dEyePBnFxcV44YUXkJOT4/d+Ynl5eQDkAesTJkxoHDR/5513oqKiAmPHjkX37t1x/PhxPP/88xgyZIjPcgOlpaXYv38/Fi5c2KHrhtZ3Ubipr+cKzURqdvKkPNg5La1DT5MkCfXuelQ7qlHjrEG1U/6z3lUPt+iGR/TAI3rgFb3wiB5I+OWHlk6jg0FrgFFrhElngklnQpQhCnGmOMSb4hFvjodJ13UrHs+aNQtfffUVfvWrX/l0QQDAww8/jPr6eqxduxbr1q3D0KFD8f777+Ohhx7y61r//Oc/kZycjDfeeAPvvvsuxo4di/fffx89evTwOe7ZZ5+FVqvFG2+8AYfDgSuvvBIfffQRJkyY4HNcWloaXnjhBTzxxBO444474PV68emnn7YYfMxmM3bs2IGHHnoIq1evRk1NDfr3749XXnkFc+fO9ev1tGbevHm44YYbcPLkyWavDfhlOYGzZ882C5uJiYnYunUrHnzwQTzyyCOIj4/H7NmzMW7cuGavvyPmzp2LkpISrFq1CgUFBcjJycGaNWuwYcOGxkUfO2rGjBm477778NZbb2HNmjWQJKlxPaEXX3wRK1asQFVVFdLS0nDLLbdg6dKlPt2MmzZtgtFo9BnY3R6C1NkYqGY7dsi7NxORemVkABdZlwUAap21OFt3Fmdrz6K0vhQ1zhp4Je9Fn9MZZp0Z8eZ4JJgTkGhORPeY7ogyRLX9RAoJXq8XOTk5uPnmm/H4448rXU7Iuuyyy5Cfn4+nn366Q89j8PFXeTmwaRN3XyciYPJkoMm+SjXOGpypPYOztWdxtu4s6lz+dQUEUrwpHt1juqN7THekR6eHXLcZ+Vq3bh3uuecenDhxAlarVelyQs727dtx44034ujRo+1euLABg4+/CguBTo6SJ6IIkZqKmom/xtHKozhScQTl9vK2n6MgraBFmjUNmfGZ6JPQBwZtaG9GSRRIDD7+qK4G1q9naw+Ryok6DWyJRtRFiSiKE3BacChdUofpNDpkxmWif1J/ZER3bO8sonDE4OOPf/0LuGDZbyJSD7dFj+pkHWw6R+PAY5vRiM/NzjaeGdpijDEYkDQA/RL7waK3KF0OUVAw+HSUzQasXcs9uYhUyGXVozpJB5vW3uLj38UZUYLwDj8AoBE06JPQB0PThyLGGKN0OUQBxeDTUV9/La/dQ0Sq4Yo2oDpJA5vm4l1ZdSYTvjSFX3dXawQIyE7IxrCMYQxAFDEYfDrC5QLeeEP1e/QQqYUr2oCqJA3sbQSeporiDCiDK4hVdT2NoMGApAEYmj6UXWAU9hh8OmLfPuCbb5SugoiCTNQKqOpmRq2+46uy15hN2GmMnFafpnQaHYamD0Vuai40Anc8ovDE4NNeXq88tsfect8+EUUGW6IJFXEeeOHx+xxfxepQK/j//FCXZEnC6F6jkWTp2EajRKGAwae9fvgB+OILpasgoiDxGLWozNC3OY6nPc5GW7BfG9l7+GkEDXJTc5GXngetRqt0OUTtxuDTXuvWyev3EFHEqU0zoyrKCRGBma3p0erwidUDSQjI6UJarDEWY3qPQZq1Y/uVESmFnbTtceYMQw9RBBI1Asp6m1ERZQ9Y6AEAndeDbpIxYOcLZdXOarx36D3sObNH6VKI2oXBpz0OHlS6AiIKMLdZh5JMPepbWZOns3q4VdDc08Tes3tR8HMBXN7ImtFGkYfBpy0OB3DsmNJVEFEA2eNNKMkQ4Q7itPMYhwNmSV1jX45XH8e7P76LagdbyCl0Mfi05fBheUYXEUWE6m4WlCY4Atq11SIJyBTVt/lnlaMK7/z4Dk5Un1C6FKIWMfi0hXtyEUUESQDO9zajytR1s61SHZE7pf1iXF4Xtv+8Hd+VcJV7Cj0MPhdTVgZUVipdBRF1kqgRUNrb1OoeW8FicLuRBnUMcm7J16e/xt6ze5Uug8gHg8/F/PST0hUQUSeJWgHnexvgCMD6PP7o6Vb3x+yeM3s444tCirq/Iy9GFIGff1a6CiLqBFEroLSXAQ5BuR3T4+wOGFT+Ubv37F7sPr1b6TKIADD4tO7kSXlGFxGFJVEj4HwvA5wKhh4AEEQJvUX1dnc1+LbkW3xzmnsdkvIYfFpz5IjSFRCRn+SBzEZFW3qaSndyZigA7CvZx/BDimPwaYkoAic4FZMoXFX0NMMhhE6LrcnpggXqWtOnNftK9uHHMs6WJeUw+LSkpARwcfVRonBUm2ZGna5rZ2+1R4akvjV9WvPFiS9wuua00mWQSjH4tIStPURhyRFnRGVU6IUeAEhyK11B6BAlEYVHC7nCMymCwaclx48rXQERdZDHpENZogeS0oW0ItrhhBCqxSnA5XXhwyMfwu1lIqSuxeBzoaoq7sROFGZEjYDz3TTwInQHEWtEEakCZ3c1VemoxI5jO5Qug1SGwedC7OYiCjsVPU1wBXHD0UBJ9XCA84WKq4px8PxBpcsgFWHwuRC7uYjCii3RhPou3orCX3Euduu0ZNepXahz1SldBqkEg09TTidw7pzSVRBRO4k6DSriwidMmFxuTmtvgVt041/H/6V0GaQSDD5NnTwpr+FDRGGhspsxpMf1tKSbyGntLTlVc4rr+1CXYPBp6uRJpSsgonZyxBlDcr2etiR6lK4gdO08uZNdXhR0DD5NsZuLKCyIGgHlieHV0tMg2uHkB28r2OVFXYHffw3sdqCmRukqiKgdqruZ4UF4Np1oRBEp4LT21pyqOYUT1ZxdS8HD4NOArT1EYcFj0qHWYFO6jE7htPaL40amFEwMPg1KS5WugIjaoTpFH7KrM7dXtIeTKC6mwl6Bnyt+VroMilAMPg3Y4kMU8jwmHer14Teg+UImd/hMwVfKnjN7IEoMiBR4DD6APIX9/HmlqyCiNlSnhn9rDwBovV6u59OGGmcNp7dTUDD4AEBFBeAJz4GSRGrhMetQH4bT11uTIOqULiHk7T27Fx6Rn80UWAw+ALu5iMJAJIztaSpW4sdvW2xuG34q/0npMijC8DsPYPAhCnEeU2S19gBAdHguQ9TluIEpBRqDD8AZXUQhri7JEFGtPQBg5oal7VJuL0dpPT+jKXAYfDweLlxIFMIkAHVGl9JlBJzB44FeEpQuIyyw1YcCicGHoYcopDkSTPCG6SrNbUkUuGFpexypPAKXN/LCLymDwae6WukKiOgi6mIit1UkTuRHcHt4RA8HOVPA8LuOwYcoZIlaAXatQ+kygibaE2kjl4KHa/pQoHAhiaoqpSuISCs/+wwrP/sMx8rLAQCXpKdjyZQpmDRoECrq6/Hoe+/hw4MHcaKiAslWK64fMgSPT5uGWLO58RzC/PnNzvvmnXfi1ssv77LXQcqyJZogIbJmczUV5REB9na1S4W9AtWOasSaYpUuhcIcgw9bfIKie1wc/nv6dPRNSYEEYPXOnZi2YgW+feQRSJKEM9XV+NsNNyAnIwPHy8tx9xtv4Ex1NTZeEHZemTMHEy+5pPHrOIuli18JKckWFdktIga3GxoA3JihfY5XH0euKVfpMijMMfgw+ATFdZde6vP1n6+/His/+wy7jh7FHVddhbfvvrvxsezkZPz5+usx+5//hMfrhU77y1L+cRYL0mL5G54aSRoBDo1T6TKCSpAkWKBDXYQO3g60Y1XHkJvK4EOdo+4xPk4n4Ijc8QOhwiuKeGv3btS7XBiRldXiMdV2O2JMJp/QAwAL33wTSQ88gF898QT++eWXkKTIbgGgXzhjDJAibvWe5qzcs6vdztWd4+wu6jR1t/iwtSeoDpw+jRFPPgmH2w2r0Yh37r4bORkZzY4rq6vD4++/j9+NGuVz/7KpUzG2f39YDAZ8+MMPWLB2LeqcTiwaO7arXgIpyBGljt/LzKJG7b+CtpsECadrTiMzPlPpUiiMCZKaf4U+fBj49FOlq4hYLo8HJyoqUG23Y+PevXjpiy/w2YMP+oSfGrsd1zzzDBKiovDewoXQa1v/7XfJe+/hla++wsn//u+uKJ8Udi7LCIcQ2V1dAHAyxoIfNDalywgbA5MGYlSvUW0fSNQKdf+eUV+vdAURzaDToU9KCvJ69cIT06fj0u7d8ewnnzQ+XutwYOJzzyHaZMI799xz0dADAFdkZuJUZSWcbi71H+kkjQCnoI4uDaNXvb97+uNM7RmlS6Awp+7gw/E9XUqUJDg98iDOGrsd4595BgadDu8tXAiTXt/m8/edPIl4iwXGdhxL4c0ZrVfF+B4AMIrqeJ2BUuOsgUfkYHDyn7rH+DD4BM3/9847mHTJJeiZkIBapxNrv/kGO376CQWLFsmh59lnYXO5sOaOO1Bjt6PGLq/VkhwdDa1Ggy3ffYdztbUYnpkJk16PwoMH8ZcPPsAfr7lG4VdGXcERrQPgX4vP8rUfoOCLb3HkZAlMRgOG5mThobtmILtHms9xRT8cwd/+uRn7fiyGVqNBTnZ3vPbf98Nk7NqFdYxieE9m37JqC7b+Y6vPfam9UrHs7WWor67He6vew8FdB1FxrgLWOCuG5A/BtHumwWw1t3LGi5MgocJegZSolECUTyrE4ENBUVpbi9+++irOVlcj1mxGbrduKFi0CNfk5GDHoUP4urgYANDnkUd8nlf85z+jd1IS9Fotlu/YgT+sXw8JQJ/kZPzPTTfhrquuUuDVUFdz6f0PA1/v/wm/mZaPS/v3hsfrxVMvv4vf/uezKHx5KSxmIwA59Mx96DncM3MSHrv3Vmi1Ghw8cgqC0PXbY2jDPPgAQEZWBn6/4veNX2t1crd11fkqVJ+vxg2/vwEZWRkoP1uON554A9XnqzH/r80XKG2vcls5gw/5Td2Dm999FygtVboKIrrAmWw93AjMWK7yqlrk3fhHrPufB3FFbj8AwPX3/jdG5Q3Eg7dPC8g1OkPUaFAYE77hZ8uqLdj32T4sXru4XccXfVSEfy7+J577/LnGgNRROck5uKonfwki/6i7xccZ+TNGiMKRJ4AL+tXWy92ocdFRAICyyhrs+7EY14/7FWYsehInzpxHVs80/Mft1+PywX0Cdt320ohi2K/eXHqiFH+a+CfojXpkDc7C9HunIyEtocVj7XV2mKJMfoceQN6+gshfHNxMRCHFY9QGbGCzKIpYtmI9hl2Sjf6Z3QAAJ86WAQCeeW0rbr32Krz6xCIM6tMTs/70NIpPnQvIdTvKFMaLGGYOysTcpXOx6PlFuO2h21B2pgxP3fkUHPXNP1/rqurw/kvvY9T0zk1HZ/ChzlBv8JEkwKWO6bJE4cRjClwIWPzcmzh07Ayef+SuxvsaevdvmzIKN0+8EoP69sSSBTcjq3sq1m//KmDX7ghTGH8UD7pyEPKuzkP3vt1xyYhLcN+z98FWa8Oewj0+x9nr7Hj+/ueRnpWO6+Zf16lrurwu2Nxc+4j8E77fbZ3ldMrhh4hCSqCCz5Ln38QnXx/AW397AOnJ8Y33pyTIe7/17ZXuc3x2zzScKVWmJcEkRc5HsSXagtReqTh/6nzjfY56B55b9BxMUSbc89Q9nermamB32zt9DlKnyPlu6yh2cxGFJLehczOrJEnCkuffRMEX+7D2qT+gR3qSz+Pd0xKRmhiHoyd9u7WKT5WiW2rL41KCTY+un00WLA6bA+dPnUdskhww7XV2PHPvM9DpdFj4PwuhNwZmHS6Hh5/h5B/1Dm5mNxdRSPJqO9cSu/i5N7H5k2/wj2ULEGUxobRC3pMvJsoMk9EAQRDwu5uvwTOrt2BgdnfkZPfA2x/uxJGTJVj5qP9TrNVq4zMbkTsqFwnpCag+X40tq7ZAo9Hg8gmXw15nx7P3PguXw4U7Hr8D9jo77HVyS010fDQ0Wv9/92bwIX+pN/hEwNoZRJFI7OT8pjVbPgMA3Prg333uf+o/5uCmCSMBAHfccDWcLg8eX7kBVbX1GJjVHWue/D16ZSR36tpqVHmuEi/9v5dQX10Pa7wVfS7tg4defQjR8dE4tOcQiv8tr9n1yPW+a3b9+b0/IykjqaVTtguDD/lLvev4lJQA772ndBVEdIFzmSY4NOr6ofZjrAnHBXW95s7KS89DXkae0mVQGFLvGB8iCk2COn8Xo45hiw/5S73BR6UNXUShTo3fmZEztLnruLwcp0n+UW/wIaKQJLHFh9pBI/DHF/lHvf9z2OJDFJICtWozRTatJnxXuyZlqTf4EFFIUmXwUeFL7iy2+JC/+D+HiEKKoMYRL4IKX3MnMfiQv/g/h4hCikZiCKC2aQV2dZF/1Bt8OMaHKCQJEbRvFQUPx/iQv9T7CaPlNw1RKNKyxYfagS0+5C/1Bh+jUekKiKgFGpHBh9oWZYhSugQKUww+RBRStB6lK+h6rk7uT6ZGUXoGH/KPeoOPyaR0BUTUAq1HfePv7Aw+HcYWH/KXeoOPRgPo1Ls5PVGo0rrVFwLsglfpEsKKAAFWg1XpMihMqTf4AOzuIgpBhnqV9XUJgIMtPh0SbYzmOj7kN3X/z2HwIQo5WpcXWqhnxo6X07I7LNYYq3QJFMbUHXw4zocoJBlEvdIldBkPl9bosDhTnNIlUBhTd/Bhiw9RSDK41fPR5NGo57UGSqo1VekSKIyp+zuOwYcoJBkc6hnz4tJy3aKOSo1i8CH/qTv4sKuLKCSpaYCzixuUdki0IZpT2alT1B18oqOVroCIWqCze6BRyceTSx0vM2DSrGlKl0BhTt3fcrGcGUAUqkyiQekSuoRDUN+CjZ3B8T3UWeoOPjExSldARK0w16ujC4hr+HQMW3yos9QdfKxW7tJOFKLMlU6lS+gSDoHBp73MOjMSzAlKl0FhTt3BB2CrD1GI0rpFGKXIn3lZK6lnIHdnZcVnKV0CRQAGH47zIQpZFkdkt8i69Tq4Ocan3bITspUugSIAgw9bfIhClrnSpXQJQWXnRsntFqWP4vgeCggGH7b4EIUsvd0DPSJ3+4o6HT+C24utPRQo/K5j8CEKaVGOyA0+1RoObG6v7HgGHwoMBh92dRGFNGupAwIic2p7hcCBze0RY4xBclSy0mVQhGDwsVoBgzoWSiMKR1q3CIsn8raXETUa1IHBpz0GJg1UugSKIAw+AJCUpHQFRHQRMRVepUsIOIc+crvwAsmgNWBgMoMPBQ6DDwAkswmVKJQZal0Rt6ZPvT6yp+oHysCkgTBo2SpPgcPgAzD4EIWB6JrI+riq1XD9nrZoBA0Gpw5WugyKMJH1SeIvBh+ikGcps0OHyFn3plITed13gdY3oS8seovSZVCEYfABgOhowGxWugoiuggBQEx9hIyLEYBKya10FSHv0rRLlS6BIlDk/PrUWampwLFjSldBRBdhPWdHTZYOnjZmQ4mCGR4YIUl6iNDKN0m+QQIgAAIkACIEAYAkQquRoIELWriggRNaOIL2Olw6PbwCg8/FZMZlIs4Up3QZFIEYfBqkpTH4EIU4QQLiqvUoi5WDjxcmuBEDj2SC26uHy62Dyy1ADMDwGY0A6HQSDHovjDon9IINeqEGmgC01NQbdAAYfFqjETS4ovsVSpdBEYrBp0FqqtIVEFEbPDorpPp02Cx6VLpEeIK4DI4oAS63AJdbhzroAEQBSIZeD5gNbhh1NphQDg06vp9YOSd0XdSglEGIMXJxWQoOBp8GycmAVgt4OeCQKJQ49cmo1/eAwxULt8cAeAB9mRseyxlF6nG7AbdbDyAWQCzMRhEWox0mTRV0Um27znFWE9mbr3aGWWfG0PShSpdBEYzBp4FGA6SkAGfPKl0Jkep5NSbUGzNR502F22Vs1iukt+kRa41FtVitTIFN2J0a2J1RAKKg1wMxZhssmnPQSM4Wj3fp9bCxm6tVw7sP57o9FFQMPk317MngQ6QQCQIcpu6oQ3fYHTGQ7Bc/PrYiFvUJ9fCIobPtg9sNlLstqEAmoiweWPWVMKLc55hqox4c39OyjOgM9E3sq3QZFOEYfJrq2RP4+mulqyBSFVHQodbcH7XOdHgd7R/8IngEJDmSUGIoCWJ1/pEA1Nl0qEMyDPpkxJjrYBHOQoAXZVruyN4SnUaHq3pepXQZpAIMPk3Fx8tr+tS2r5+eiPwnQYM6cz9Uu7rDa/NvtK+xxojY5FhUS/53ed1y9y0oOd88PF0/8Xr84a4/+H3eBi43UOa2Qqvti7ioepwTznX6nJFoRPcRnL5OXYLB50I9ewLff690FUQRS4KAenM2qt294LF3/iMotjwWtiQb3KJ/3UernlwFr/jLpIbiE8V4cNmDyB+R3+namvJ6gfPuZHhq+8McdQp2zU8A2PoDANnx2dyIlLoMg8+FGHyIgsZm6oUqbxbc9sANXhVEAcn1yThj9m+WV1xsnM/Xa99Zi25p3TDkkiGdL+4CNr0FXq8W9ppe0OvTobEcglNQZnZaqIgxxmBUr1FKl0Eqwi0rLpSRAeiYB4kCyaONwjnTVTjvGAC3O/AzdvT1eiRKiZ0+j9vtRuG/CjFp7CQIghCAynxVakxNrmWAs3owzK4roJXUuWWORtDg6qyrOYuLuhSDz4W0WqBbN6WrIIoY9eYsnJVGwuGICup1rOVWxGg6t+jd5998jrr6Okz69aQAVfULSW9AvdR8LJPdFgep9iqYxX4Bv2aou6LbFUiyJCldBqkMg09LevZUugKisOfVGHHePBxl9r4Qxa75qIk7Hwezxv/Wk20fb8OvLvsVkhIC/8PYaWo9+ImiBvaaTJicI6GBqdXjIkmfhD4YnDpY6TJIhRh8WsLgQ9QpdlMPnBVGwWaP7dLrCpKApMok6DUd38W9pLQERQeKMOXqKUGoDKjRth1oHPZoCLVXwShlBKWGUNEjpgfye+crXQapFINPS6KigCQ2vxJ1lAQNKszDUOrIgderzIZUGrcGKbUp0Agd+3j74NMPEBcTh+F5wwNflFaLSql941i8Xi2c1YNh8VwKSIEfZ6S0lKgUXJN9TYf/fYgChf/zWtOXq4cSdYRXY0Sp8UrU2js/yLizdHYd0uxp7f7hKooiPvjkA0zMnwidNvCTG5yWaHR0w3hbXRpMruEQImjybZwpDhP7TIROEzmvicIPg09r+vaV9+8ioja59bEo0VwJh9OidCmN9HX6doefov1FOFd2DteOuzYotVRo/XtfHPYY6G1XQSsFd2B4V4jSR+HavtfCpFPHGCYKXYIkSR39RUQ9PvwQOHZM6SqIQprTkIJSz6VdNoC5o9xWN0rMJRAlZRYLlPRGHLKkdeocWq0XWut3cAnnA1RV17LoLZjSbwpXZqaQEJqfVKGin/qmlxJ1hN3UHefcQ0I29AByy0+qPVWxMSU2s7XT5/B6tfDUXgajlB6AirpWnCkO1w+4nqGHQkboflqFgp49AbM6FxYjaku9ORPnHZdACoMBuIY6A1LtqdAKXT/g+rwQmM8QURTgqh0MkxQ+64ylRqViWv9psBo6H/6IAoXB52I0GqBPH6WrIAo5dlMPlNv7dXjArpIMdQak16b7NdXdX16zBQ4ELmxJogBnzSVhMd29d1xvTO43GUadUelSiHww+LSlf3+lKyAKKU5DCs47B4ZV6GmgdWiRXpEOs7ZrWnKrg9DSIUkCXLWDYETnxg0FU05yDq7Juoaztygk8X9lWxISgMREoLxc6UqIFOfWx+K8NzcsurdaI3gEpJSmoCq5CtVidfAupNXhPDoWsD5YuxzfflGAkpNHYDCakJUzFDPueghpPbJ9jpNEAe6awdDHOOBGVQCL7hyNoMHw7sMxKGWQ0qUQtYotPu3BVh8ieLVmlErDFFuYMKAkIK40Dineji902F52P9bu+Wn/18if9hs89Pw7uP/J1+H1ePDsf/4WTrut2bGiqIFUlxcyG5xGG6Ixtf9Uhh4KeZzO3h4OB7B2LeDxKF0JkSJEQY9z+ivhckXeeA2v0YvyuHLYvfaAnvd4XHfYW9iUtCNqq8rxxxvz8OD/rEO/3CtaPMZgcMBt+RISlPt8yorPwuheo7nLOoUFtvi0h8nEqe2kWhIEnDdeEZGhBwC0Ti2SzyUjUUqEgMB04XnNUZ0OPQBgr68FAERFx7V6jMtlgsk1rNPX8odBa8Cve/8aV2ddzdBDYYPBp71ycwEhfMc1EPmrxnwJHI7wXzn4YgQIsJZbkW5Lh1HT+YBXZYzu9DlEUcT6FcuQfckwdMu8eHe73RYLs9i1XfK943rjxpwb0TeR2/tQeOHg5vaKiQEyM4GjR5WuhKjLOA3JqLaHz7oxnaW36ZFqS4U9wY4KbQW8ktePkxhQJnU+PL353GKcOXYI//HMxnYd76jtBUNsOVwo6/S1LybeFI+RPUaiW4x6/l9QZGHw6YhLL2XwIdUQBR3KpUFhOW29MwQIsFRYYNKZUBtfi2qpGlIH3oUaS2yn37M3n1+CA19/gj/+z3rEJ7dvtWZJEiDW50KwfA5JcHeyguaMWiOGZQxDTnIOBLZ+Uxhj8OmI5GQgPR04e1bpSoiCrso0BG67esdtaDwaxJ6PhdVkRVVMFerEurafpNOhpINT2JuSJAlv/e+j2PdFAR74+1tISu/Roed73HqYPZfBrv/G7xoupBE0GJA0AMMyhnGDUYoIDD4ddemlDD4U8eymHqi1JypdRkjQOrRIdCQi1hyL2uha1Iq1rbYA1VniIHZigPSbzy3GN59sxoJl/4DJEoXqilIAgDkqBgZj+0KHvT4epthucAin/a4DkAcuD0gagEEpg7jlBEUUTmf3x8aNQEWF0lUQBYVXY8JZ4arIWK8nCLxGL+pi6lCDGt8d37VaHLZ2g7cTwWf+1b1bvH/OfzyFkRNuavd5dHo3vFH/8muKu9VgxaCUQRiYNBB6bddt70HUVRh8/PHTT8COHUpXQRQUZeYrUG+PU7qMkCfpJNTH1qNOWwen6IQtJhEnhNBpGbFYz8Gm29fu41OiUjAoZRCy4rMU28meqCsw+PhDFIG33gLq2tHnTxRGXPoEnHVfrnQZYcdp9aAoPhY2gwNe+DETLBgEwBCzBy6h9e12UqJSkBWfhaz4LHZnkWpwjI8/NBrgssuAzz9XuhKigKrSDgQCPyEo4pWLSag9GQsAMMY6oI21waW3waNkCJIAjXMgYPrC526GHVI7tvj4S5LksT6VlUpXQhQQDmM6zjlzlS4j7Hi1WnwmZsAtNe8e0pk80FudEMwuePUuuAUXRIgtnCVYBCQlHkdaohbp1nSkR6dzZhapHlt8/CUIwBVXANu3K10JUUBUSdyWxR9njDFw21oeE+Nx6OBx6AD8svK13uKGzuqEYHLBq3PBLbg7HYYEaKCVNNBCC41XDzgN8NYb4arTA9U9MXJIp05PFFEYfDqjZ08gIwM4c0bpSog6xWbqBaeDLQEd5dFpccjese0p3DY93Dbf2VKCRoLW4IWg90KjF6HRioBGgqARAUECNBIkUQBEDSSPFpJHA9GtgejWwuvWQJIEeIAW53CVlQHHjgG9e/v7KokiC4NPZw0fDmzapHQVRH6TIKDKm6V0GWHplD4WXk/nVzGWREFuGXIE5yN5zx4GH6IGnLPYWUlJQJ8+SldB5DebORNut3pXaPaXW6/HYXt4DA6uqGDDNFEDtvgEwq9+BRQXA94QmcZK1AG13s5tNrn8g+Uo+LYAR0qOwGQwYWjWUDw04yFkp2U3HlNaXYon3n4Cnx/8HPWOemSlZuHea+/FpKGTOlu+Yn7UJHRqleau9v33cs88kdqxxScQrFZg0CClqyDqMJchEU6XpVPn+Pqnr/Gb/N/gnYfewev3vw6P14PfPvtb2Jy2xmMefOVBHD13FC8teAkFSwow8bKJWPjiQvz7xL87+xIUUWWOwhlneI2JOn4csNnaPo4o0jH4BMpllwFGo9JVEHVIrTaz0+d47f7XcNPIm9Avox9yeuTgb3P/htMVp3Hg+IHGY4qOFmHOr+dgSOYQ9Ezuifsm34cYS0xYBh9Ro8F3znily+gwUQQOHlS6CiLlMfgEisEgd3kRhQlR0MHmTAj4eWvttQCAuKi4xvvysvKwdc9WVNVXQRRFvLf7PTjdTgzvNzzg1w+2Y8Z4OMTw3Mfs4EE5ABGpGRcwDLQtW7h7O4WFenMWyux9A3pOURRx54o7UWOrwcY/bWy8v9pWjXv/cS8+/+Fz6DQ6mA1mLJ+/HKNzRgf0+sFmNxrxL2ea0mV0yjXXAJmdb+gjClts8Qm00aMBHceMU+irkwI/0nXxm4tx6MwhPH/X8z73/8/m/0GNrQZv/P4NvPfwe7jj6juw8MWF+PH0jwGvIXgE/FsMfAtZVysuVroCImUx+ARabCyQl6d0FUQX5dWa4XBEtX1gByx5cwk+OfAJ3nrgLaTHpzfef/z8cazesRpPzXkKVw68Ejk9cvD7636P3F65eG3HawGtIZjOWaJREQHT/k+cYHcXqRuDTzDk5srr+xCFKLshcK09kiRhyZtLULCvAGv/sBY9knr4XstlBwBoBN+PG41GA0kMj552j06Hf9tjlS4jIFwuoKRE6SqIlMPgEwyCAOTny7u4E4UghxS4LpvFby7GO1+/g2fveBZRpiiUVpeitLoUDpcDAJCdlo3eKb3x8JqHsa94H46fP45/FP4DXxz8AuOHjA9YHcH0ky4BnhY2IQ1Xx44pXQGRcji4OZh27wa+/VbpKoiaOa0bB48nMGPRes/v3eL9T815CjeNvAkAUHyuGE++8yT2/LwH9c569Erphd9d8zvMGD4jIDUEU43Jgp2OZKXLCKjoaGDmTKWrIFIGg08web3A228DVVVKV0LUyK2LwRnPCKXLCAuiRoOvhHTUeyNvwsKNNwIJ4T9Wm6jDIqftNhRptcCYMXLXF1GIcOjDezp2VzpsSIzI0AMA584pXQGRMhh8gi01FRgyROkqiBoFcnxPJDtvicYxR+e28whl588rXQGRMhh8usKwYdwdkEKG0x0eO4oryWEwYJ8t/Lal6IjSUqUrIFIGg09XEARg7FjAbFa6ElI5tz4WXm94brfQVUSNBnvF5LDaed0fVVWAx6N0FURdj8Gnq1gswLhxHO9DivJoY5QuIeT9ZEhEbYBmvIUyUQTKy5WugqjrMfh0pYwMrupMinILgV2tOdKct8TgeASP67kQx/mQGjH4dLXLLgO6d1e6ClIpr6CeH+od5TAYsc8Wp3QZXaq6WukKiLoeg09XaxjvE8XfvKnruUWT0iWEJFGjQZGYFPHjei5UX690BURdj8FHCSaTPN6HW1pQF/N4jUqXEJIOGRJRp4JxPReqq1O6AqKux5+8SklLA664QukqSGU8Hr3SJYScUksMTqhoXE9TbPEhNWLwUdLgwcCgQUpXQSrh1VogSerqymlLvcmE71Q2rqcpu12e3UWkJgw+ShsxAujdW+kqSAW8WnW2arTGYTDga2fkr9fTFptN6QqIuhaDj9IaBjunpChdCUU4id/ujdx6Pb72pMAt8T1xOJSugKhr8bs+FOh0wMSJQAwXl6PgkQR+uwOAV6vFbikFDpErWAPs6iL14SdhqDCZgGuvlf8kCgaO75G3o9CkqGJl5vaSJKUrIOpaDD6hJCZGbvnR8UOZAk9S+XYpkiDg3/pkVLgNSpcSUhh8SG0YfEJNSoo85kflP6QoCFTe1XXImISzTraoXohdXaQ26v4kDFW9ewNXXql0FRRh1DyVvdicoKo9uDqCLT6kNgw+oSonh+GHAkulLT5nzLH4yR6tdBkhi8GH1Eadn4Th4pJLgJEjla6CIoQA9fVplJujccAep3QZIY3zKUhtGHxC3aBB8iKHRJ2kEdW1YEuF2Yoie7zSZYQ8Bh9SG04fCgeDB8uDnb/6SulKKIxpVRR8zltisNfG0NMeDD6kNmzxCReDBgGjRildBYUxjdeudAld4qwllqGnnfR6rp5B6sPgE04GDgTy8znVnfyikTzQaCJ7nM9JSzz2q3jT0Y5iaw+pEYNPuOnXDxg3DtDwn446TqtzK11C0BSbE/CDjdu+dITZrHQFRF2PPz3DUVYWMHkyYDQqXQmFGZ3gUrqEgJMEAT+akjll3Q/cHpDUiMEnXKWnA9dfz08u6hCdJrIGOIsaDfYbUrg4oZ8SEpSugKjrMfiEs9hYOfykpytdCYUJPeqULiFgPDoddmvTUMJtKPyWmKh0BURdj8En3JlMcrdX375KV0JhwOgpU7qEgHAaDNgppaHKrVe6lLDGFh9SIwafSKDRAL/+NTBsmNKVUIjTuyvDfmZXtTkKX7pTYfNqlS4lrBmNQFSU0lUQdT0Gn0gydKg840vLHwjUMgESDIZwXc9HwHFzAnbZk+CW+NHVWWztIbXi0lWRJjsbsFqBwkLAZlO6GgpBRk0NHAivX/U9Oh0OaJJQaudMxkBJSVG6AiJl8NemSJSaCtx4I9Cjh9KVUAgyiuVKl9AhdSYzvhDTUOpi6Amkbt2UroBIGQw+kcpkAiZNAoYP52KH5MPoOq90Ce12yhyHLx0pcIrsvg0kjQZIS1O6CiJl8CdipMvNBaZN43o/1EgjuqA3OJUu46K8Wi0OGFPxvT1W6VIiUloa9+gi9WLwUYPkZGDGDHn8DxEAi65C6RJaZTOa8BXScYbr8wRNz55KV0CkHAYftTAY5Blfo0fzVz1ClPuE0iW06JwlBl84UzhVPch69VK6AiLl8Ceg2gwYILdzf/QRUBG6v/VTcOndVTAYnHCFyIBht06HH7UJOGPjrpnBFh8vL/pOpFZs8VGjuDi562vYMK75o2JR2nNKlwBAQIklFp95M3DGydDTFfr3V7oCImUx+KiVRiMveHjjjUBGhtLVkAKiXMcVvb7daMQ3+jR8Z4uDVxIUrUUtNBqgXz+lqyBSFoOP2sXGAlOmAPn58hR4Ug2t1waTqb7LrytqNCg2J+BfzjRUug1dfn0169WL3+ZEHONDsn795Kkeu3YBP/2kdDXURaKEc3Agq8uuV22Own5XPGx2drEqgd1cRIAgSZKkdBEUYk6fBj7/HKipUboSCjJR0OO0kA9RDG7jr0enwyFdAk45OI5HKVFRwG23AQJ7FUnl2NVFzXXrBtx0E5CXx6nvEU4juRFtCuYgZwGllhh85k1n6FHYwIEMPUQAW3yoLXY7sHcvcPAgIIpKV0NBIGoMOI0xAW/1qTFZcMgbiwqO41GcwSC39hj4T0HE4EPtVFsL7NkD/PwzwP8yEafKkotqW3pAzlVrMuMnMQ5lLv6UDRXDhsmTOImIwYc6qqIC+OYb4ERorvxL/vFqjDiDMRBF//tC6kxm/CTG4nyILIpIMqMRmDmTrT1EDRh8yD8lJXIAKilRuhIKkCrLpai2dXzL7jqjCT8jDuecDDyhiK09RL4YfKhzTpwA9u1jAIoAXo0JZzC63a0+NqMJhxGLEm4mGrKMRnlsj16vdCVEoYOzuqhzevYEpk6Vt8Do00deGpbCklZ0INrUdoC1G404YEzF585Uhp5WbN/+35g/X8C6db9v9pgkSXjuuUmYP1/Avn3vBrWOYcMYeoguxLnKFBhJScDYscAVVwDffy/PAnM6la6KOijW/j3qdUnweC78aSmg2mTGCSkaZxh2LurYsd34179WoXv33BYf//jjZyB0wbzylBQgJyfolyEKO/z1nAIrKgr41a+AWbOAq67iNtBhRpC8SND+2Pi1V6vFGXMsvtBmYJcjmaGnDQ5HHV5+eRZ+85t/wGKJb/b4yZP7UFj4d/z2t/8Mah0aDTB6NNftIWoJgw8Fh04n/7p5yy3AxIlA9+78FA4TZucZ6BI9OGROwifebjhgj0O9l43D7fHmmwsxePBkDBx4dbPHXC4bXn75NsycuRyxsR0fRN4RgwcDCQlBvQRR2OKnGQVfz57yzWaT1wE6fBgoL1e6KrpQVJS8Z1v//kgyxqB0A8AlK9tv9+63cOLEXjz88O4WH1+//g/IyhqJIUOmBbWO6Gh50XUiahmDD3UdiwXIzZVvlZVyAPr5Z6CuTunK1EuvB3r0kHevbNIqZ4TcVbJ9u7LlhYuKipNYt+5+/P73hdDrm3cHfvfdezh06BP8v//3bVDrEAT53407zRC1jtPZSXlnz8oh6OhRwOVSuprIZzIBvXoBmZnyvmza1ndK/9e/gB9/bPVh+j/79r2LlSunQ6P55b0URS8EQYAgaDB69D347LPlEATNBY9r0LfvKDz44I6A1JGXx9YeorYw+FDo8HrlneFPnABOneLu8IFktcpBp3dvIC2t3eOtvF5gyxagtDS45YU7h6MW5eXHfe5bvfp2pKUNwIQJ/wmrNQl1dWU+jy9bNhi33PIscnOvQ1JSZqdr6N4dmDSJQ+mI2sIGUQodWu0v44EAOficPCmHoDNnALdb2frCTUKCHHR695aXG/CDVgtccw2waZO8Xy21zGSKRrdug3zuMxqjEBWV2Hh/SwOaExJ6BiT0WK3yahIMPURtY/Ch0BUTA1xyiXwTRXl16JMn5VtFhdLVhRaNRg43aWlAerr8pzEwW0hERcnhZ+tW+Z+BQotGA1x9tdyDSURtY1cXhSe7Xe5/abidP6+u8UE6HZCa+kvQSUkJ+ojWH34AvvgiqJcgP4waBQwcqHQVROGDwYcigyQB1dVAWZl8Ky+X/4yE1aOtViAuDoiPl2+JifJNge1BvvhCDkAUGrgBKVHHMfhQZKurkwNRbW3zm82mdHW/EAR5AZamAafh7yG22dKOHcBPPyldBeXmAsOHK10FUfhh8CH18njkYNQQhOrq5O4yl0seSN30z4a/e70XP6dGI98EQf5TqwXMZvlmsfzy9wvvM5nCZmSqJAGffiovwUTK6N8fGDNG6SqIwhODD1FHiOIvY4kawk3ToKMSogh8/DFQXKx0JeqTmSkPZg6TnEwUchh8iMgvogh8+KG87BJ1jT59gPx8VWVsooBj8CEiv4mivLozx/wE36WXAldcoXQVROGPwYeIOu3bb4HdLe/NSZ0kCMCIEcCgQW0fS0RtY/AhooA4elQe9NzW+G9qP61WXpE5s/OLOxPR/2HwIaKAKS0FCgq4vUUgWK3AuHHyOpVEFDgMPkQUUPX1csvPmTNKVxK+MjOB0aMDtusIETXB4ENEQbF/vzzuh11f7afTyeN5uAUFUfAw+BBR0FRUAJ98wj1l2yMhQe7aio9XuhKiyMbgQ0RB5fXKLT8HDsirPpMvrVaeqn7ZZfLfiSi4GHyIqEtUVgI7dwKnTildSejo1g246iogNlbpSojUg8GHiLrUyZNyAKqqUroS5cTGyhuM9uqldCVE6sPgQ0RdThSBgweBoiLA4VC6mq5jtcrdWgMHctsJIqUw+BCRYjweebuLAweA6mqlqwmehAQ58GRnM/AQKY3Bh4hCwvHj8hT4s2eVriRw0tKAIUOAnj2VroSIGjD4EFFIKSsDfvgBOHYsPLvBoqLklp2+fYHERKWrIaILMfgQUUgSReD0aXkPsGPHAKdT6YpaZzDIqy337Qukp8sbixJRaGLwIaKQJ4ryNPjjx+WtMJQeDyQIQFISkJHxy41r8BCFBwYfIgo7Nps8Fqi0FDh3DigvD+7WGEYjEBcnbxiakSGP3TEYgnc9IgoeBh8iCnuSJG+OWlPzy622Vr45nfLssYZb04AkCHKA0evlPw0GwGQCYmLkoBMXJ6+5YzYr9cqIKNAYfIhIVSRJDj+SJAceIlIXBh8iIiJSDS6lRURERKrB4ENERESqweBDREREqsHgQ0RERKrB4ENERESqweBDRGFj/fr1SEhIQF1dnSLXz8/PR35+viLXbo/t27fDarXi/PnzSpdCFLIYfIgIACAIQrtuO3bs6PS1bDYbli5d2qFzeb1ePProo7jvvvtgtVqxd+9eCIKARx55pNXnHD58GIIg4IEHHuh0zV1l27ZtWLp0qV/PnThxIvr06YMnnngisEURRRCu40NEAIA1a9b4fP3aa6+hsLAQr7/+us/911xzDVJTUzt1rbKyMiQnJ+PRRx9t9w/5d999FzNmzMDJkyfRrVs3AMDAgQPhcrlw5MiRFp/z2GOPYenSpSgqKsLQoUM7VTMAuFwuAIAhiPtV3HvvvVi+fDn8/WheuXIl/vjHP6KkpATR0dEBro4o/OmULoCIQsPs2bN9vt61axcKCwub3a+UV155BVdeeWVj6AGAWbNmYfHixdi1axeGDx/e7DlvvvkmBgwY0OnQY7PZYLFYghp4AuWGG27Afffdhw0bNmDevHlKl0MUctjVRUTtJooinnnmGVxyySUwmUxITU3F/PnzUVlZ6XPcnj17MGHCBCQlJcFsNiMzM7Pxh/CxY8eQnJwMQG6RaehCu1jLj8PhwPbt23H11Vf73D9r1iwAwNq1a5s9p6ioCIcOHWo8ZvPmzZg8eTIyMjJgNBqRnZ2Nxx9/HN4LdjfNz8/HoEGDUFRUhNGjR8NiseDhhx9ufKzpGB+Xy4UlS5YgLy8PsbGxiIqKwqhRo/Dpp5/6nPPYsWMQBAF/+9vf8OKLLyI7OxtGoxGXX345du/e3Xjc3LlzsXz5cgC+XY8N3nrrLeTl5SE6OhoxMTEYPHgwnn32WZ9rpaSkIDc3F5s3b271/SRSM7b4EFG7zZ8/H6+++ipuv/12LFq0CMXFxfjf//1ffPvtt/jyyy+h1+tRWlqK8ePHIzk5GQ899BDi4uJw7NgxbNq0CQCQnJyMlStX4p577sH06dMxY8YMAEBubm6r1y0qKoLL5WrWcpOZmYmRI0di/fr1ePrpp6HVahsfawhDt912GwDg1VdfhdVqxQMPPACr1YpPPvkES5YsQU1NDZ566imf85aXl2PSpEm49dZbMXv27Fa79mpqavDSSy9h5syZuOuuu1BbW4uXX34ZEyZMwDfffIMhQ4b4HL927VrU1tZi/vz5EAQBf/3rXzFjxgwcPXoUer0e8+fPx5kzZ1rsYiwsLMTMmTMxbtw4PPnkkwCAgwcP4ssvv8T999/vc2xeXh7efffdVt9PIlWTiIhasHDhQqnpR8Tnn38uAZDeeOMNn+O2b9/uc/8777wjAZB2797d6rnPnz8vAZAeffTRdtXy0ksvSQCkAwcONHts+fLlEgCpoKCg8T6v1yt169ZNGjFiRON9Nput2XPnz58vWSwWyeFwNN43ZswYCYD0wgsvNDt+zJgx0pgxYxq/9ng8ktPp9DmmsrJSSk1NlebNm9d4X3FxsQRASkxMlCoqKhrv37x5swRA2rJlS+N9F77vDe6//34pJiZG8ng8zR670F/+8hcJgHTu3Lk2jyVSG3Z1EVG7bNiwAbGxsbjmmmtQVlbWeMvLy4PVam3s3omLiwMAbN26FW63OyDXLi8vBwDEx8c3e+yWW26BXq/36e767LPPcPr06cZuLgAwm82Nf6+trUVZWRlGjRoFm82GH3/80eecRqMRt99+e5t1abXaxnE/oiiioqICHo8Hw4YNw969e1ustelrGDVqFADg6NGjbV4rLi4O9fX1KCwsbPPYhmuUlZW1eSyR2jD4EFG7HD58GNXV1UhJSUFycrLPra6uDqWlpQCAMWPG4IYbbsBjjz2GpKQkTJs2Da+88gqcTmena5BamOmUmJiICRMm4J133oHD4QAgdynpdDrcfPPNjcd9//33mD59OmJjYxETE4Pk5OTGgdvV1dU+5+zWrVu7BzKvXr0aubm5MJlMSExMRHJyMt5///1m5wSAnj17+nzdEFAuHCPVkgULFqBfv36YNGkSunfvjnnz5mH79u0tHtvwPjUdH0REMo7xIaJ2EUURKSkpeOONN1p8vGHAsiAI2LhxI3bt2oUtW7agoKAA8+bNw9///nfs2rULVqu1w9dOTEwEIAeE7t27N3t89uzZ2Lp1K7Zu3YqpU6fi7bffbhxnBABVVVUYM2YMYmJisGzZMmRnZ8NkMmHv3r34z//8T4ii6HO+pq1DF7NmzRrMnTsX119/Pf7jP/4DKSkp0Gq1eOKJJ1qcYt90DFJTLQW6C6WkpGDfvn0oKCjABx98gA8++ACvvPIKfvvb32L16tU+xzYEqaSkpHa9DiI1YfAhonbJzs7GRx99hCuvvLJdwWD48OEYPnw4/vznP2Pt2rWYNWsW3nrrLdx5550dbokYMGAAAKC4uBiDBw9u9vjUqVMRHR2NtWvXQq/Xo7Ky0qeba8eOHSgvL8emTZswevToxvuLi4s7VMeFNm7ciKysLGzatMnnNT366KN+n/Ni743BYMB1112H6667DqIoYsGCBVi1ahUWL16MPn36NB5XXFyMpKSkxuBHRL9gVxcRtcvNN98Mr9eLxx9/vNljHo8HVVVVAOTWhgtbMBpmNzV0d1ksFgBofE5b8vLyYDAYsGfPnhYfN5vNmD59OrZt24aVK1ciKioK06ZNa3y8oaWlaV0ulwsrVqxo1/Vb09J5v/76a+zcudPvc0ZFRQFo/t40jHNqoNFoGmfCXdiNWFRUhBEjRvhdA1EkY4sPEbXLmDFjMH/+fDzxxBPYt28fxo8fD71ej8OHD2PDhg149tlnceONN2L16tVYsWIFpk+fjuzsbNTW1uIf//gHYmJicO211wKQg0pOTg7WrVuHfv36ISEhAYMGDcKgQYNavLbJZML48ePx0UcfYdmyZS0eM3v2bLz22msoKCjArFmzGgMEAIwcORLx8fGYM2cOFi1aBEEQ8Prrr/u9OnKDKVOmYNOmTZg+fTomT56M4uJivPDCC8jJyfF7P7G8vDwAwKJFizBhwgRotVrceuutuPPOO1FRUYGxY8eie/fuOH78OJ5//nkMGTIEAwcObHx+aWkp9u/fj4ULF3bqtRFFLAVnlBFRCGttWvWLL74o5eXlSWazWYqOjpYGDx4s/elPf5LOnDkjSZIk7d27V5o5c6bUs2dPyWg0SikpKdKUKVOkPXv2+Jznq6++kvLy8iSDwdCuqe2bNm2SBEGQTpw40eLjHo9HSk9PlwBI27Zta/b4l19+KQ0fPlwym81SRkaG9Kc//UkqKCiQAEiffvpp43FjxoyRLrnkkhavceF0dlEUpb/85S9Sr169JKPRKF122WXS1q1bpTlz5ki9evVqPK5hOvtTTz3V7JwXvnaPxyPdd999UnJysiQIQuO/wcaNG6Xx48dLKSkpksFgkHr27CnNnz9fOnv2rM/5Vq5cKVksFqmmpqbF10Ckdtyri4jCgtfrRU5ODm6++eYWu9tIdtlllyE/Px9PP/200qUQhSQGHyIKG+vWrcM999yDEydO+DU7LNJt374dN954I44ePYqUlBSlyyEKSQw+REREpBqc1UVERESqweBDREREqsHgQ0RERKrB4ENERESqweBDREREqsHgQ0RERKrB4ENERESqweBDREREqsHgQ0RERKrB4ENERESqweBDREREqsHgQ0RERKrB4ENERESqweBDREREqsHgQ0RERKrx/wNRyHzk6o9Q7AAAAABJRU5ErkJggg==",
      "text/plain": [
       "<Figure size 640x480 with 1 Axes>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "train_vars = set(get_variants(docs['train']))\n",
    "val_vars = set(get_variants(docs['validation']))\n",
    "test_vars = set(get_variants(docs['test']))\n",
    "\n",
    "from matplotlib_venn import venn3\n",
    "venn3([train_vars, val_vars, test_vars], ['Train (Variants)', 'Validation (Variants)', 'Test (Variants)'])"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "d0e7b6e3-a816-4f75-b774-2ca9126a2351",
   "metadata": {},
   "source": [
    "## Show annotation example"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 11,
   "id": "794bd210-10cb-47ad-95f1-9d5eb0f54f2b",
   "metadata": {
    "tags": []
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<span class=\"tex2jax_ignore\"><div class=\"spans\" style=\"line-height: 2.5; direction: ltr\">Anlageträger für ein HNPCC haben \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    Mutationen\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Variant\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "\n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    in\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "</span>\n",
       "\n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    den\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "</span>\n",
       "\n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 77px;\">\n",
       "    Mismatch\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "\n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 77px;\">\n",
       "    -\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "</span>\n",
       "\n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 77px;\">\n",
       "    Repair\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "</span>\n",
       "\n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 77px;\">\n",
       "    -\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "</span>\n",
       "\n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 77px;\">\n",
       "    Genen\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "</span>\n",
       ". Bislang konnten Keimbahnmutationen in 5 verschiedenen Genen nachgewiesen werden : \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MSH2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MLH1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MSH6\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PMS2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "und \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    EPCAM\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ". Fast 86 % der bislang identifizierten Mutationen liegen in den Genen \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MSH2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "und \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MLH1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "[ REF ] , etwa 10 % im \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MSH6\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "- Gen und 2 % im \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PMS2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "- Gen . Mutationen im EPCAM - Gen werden bei ca. 2 % der Familien gefunden [ REF ] . Vor einer prädiktiven genetischen Untersuchung muss entsprechend des GenDG eine human - genetische Beratung erfolgen . Eine prädiktive Testung ist in der Regel nur möglich , wenn in der Familie bei einem bereits erkrankten Mitglied eine zweifelsfrei pathogene Mutation nachgewiesen wurde . Der Nachweis von Polymorphismen oder Mutationen mit unklarer pathogenetischer Bedeutung eignet sich nicht als Grundlage für eine prädiktive genetische Diagnostik . </div></span>"
      ],
      "text/plain": [
       "<IPython.core.display.HTML object>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "from spacy import displacy\n",
    "def show(d):\n",
    "    displacy.render(d, style='span', options={'spans_key' : 'entities'})\n",
    "show(all_docs[13])"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 12,
   "id": "acc9da26-06c5-444c-b616-356010a56289",
   "metadata": {
    "tags": []
   },
   "outputs": [
    {
     "data": {
      "text/plain": [
       "1    2419\n",
       "2      91\n",
       "3      24\n",
       "4      10\n",
       "5       6\n",
       "Name: count, dtype: int64"
      ]
     },
     "execution_count": 12,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "import pandas as pd\n",
    "pd.Series([len(g.split(' ')) for g in get_genes(all_docs)]).value_counts()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 13,
   "id": "6faf02d4-3fdf-467e-aa96-a4ba5ef97c2e",
   "metadata": {
    "tags": []
   },
   "outputs": [
    {
     "data": {
      "text/plain": [
       "1     435\n",
       "2     156\n",
       "3     151\n",
       "4      39\n",
       "5      37\n",
       "6      11\n",
       "7       9\n",
       "8       8\n",
       "12      2\n",
       "11      1\n",
       "Name: count, dtype: int64"
      ]
     },
     "execution_count": 13,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "pd.Series([len(g.split(' ')) for g in get_variants(all_docs)]).value_counts()"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "c9ec03fe-e764-4234-bb68-f3778bca67f4",
   "metadata": {},
   "source": [
    "# Performance Evaluation"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 14,
   "id": "ca3b3acb-17c8-42af-896d-c7c94ac4113b",
   "metadata": {
    "tags": []
   },
   "outputs": [],
   "source": [
    "from tqdm.auto import tqdm\n",
    "from xmen.data import from_spacy\n",
    "from xmen.evaluation import evaluate, error_analysis"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 15,
   "id": "4f90e529",
   "metadata": {
    "tags": []
   },
   "outputs": [],
   "source": [
    "import spacy\n",
    "from spacy_ner import chunk_and_ngram_suggester\n",
    "cp = '2024-05-23_14-52-36-cuda-1' # Replace with your training directory\n",
    "model = spacy.load(f'spacy_ner/training/{cp}/model-best/')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 16,
   "id": "b21f877a-9e7d-423f-9991-1fd3de6499dc",
   "metadata": {
    "tags": []
   },
   "outputs": [],
   "source": [
    "test_docs = docs['test']"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 17,
   "id": "d7b2f9f3-d3cc-4288-b486-f8d8a2fc3bc6",
   "metadata": {
    "tags": []
   },
   "outputs": [],
   "source": [
    "gt_test = from_spacy(test_docs, span_key='entities', doc_id_key='file')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 18,
   "id": "3574d03c-68ca-4991-8d8e-5ad5d5dc607c",
   "metadata": {
    "tags": []
   },
   "outputs": [
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "4291fcfbd11f4e9baef05bd243d178a6",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "  0%|          | 0/52 [00:00<?, ?it/s]"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "pred_test = list(model.pipe((t.text for t in tqdm(test_docs)), batch_size=16))"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 19,
   "id": "70993b75-53f0-47c1-a838-06d77cafd2ec",
   "metadata": {
    "tags": []
   },
   "outputs": [],
   "source": [
    "for t, pt in zip(test_docs, pred_test):\n",
    "    pt.user_data['file'] = t.user_data['file']"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 20,
   "id": "98dcfd8f-90f6-4684-b3b0-c6a6bb18bfd7",
   "metadata": {
    "tags": []
   },
   "outputs": [],
   "source": [
    "pred_test_ds = from_spacy(pred_test, span_key='entities', doc_id_key='file')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 21,
   "id": "154a3c76-56e3-4bb7-b028-6db4ea5708f6",
   "metadata": {
    "tags": []
   },
   "outputs": [
    {
     "data": {
      "text/plain": [
       "{'strict': {'precision': 0.8810679611650486,\n",
       "  'recall': 0.7515527950310559,\n",
       "  'fscore': 0.8111731843575418,\n",
       "  'ptp': 363,\n",
       "  'fp': 49,\n",
       "  'rtp': 363,\n",
       "  'fn': 120,\n",
       "  'n_docs_system': 52,\n",
       "  'n_annos_system': 412,\n",
       "  'n_docs_gold': 52,\n",
       "  'n_annos_gold': 483},\n",
       " 'partial': {'precision': 0.927035914087167,\n",
       "  'recall': 0.7785957195294001,\n",
       "  'fscore': 0.8463564820591893,\n",
       "  'ptp': 381.9387966039128,\n",
       "  'fp': 30.061203396087194,\n",
       "  'rtp': 376.06173253270026,\n",
       "  'fn': 106.93826746729974,\n",
       "  'n_docs_system': 52,\n",
       "  'n_annos_system': 412,\n",
       "  'n_docs_gold': 52,\n",
       "  'n_annos_gold': 483}}"
      ]
     },
     "execution_count": 21,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "evaluate(gt_test, pred_test_ds, ner_only=True, metrics=['strict', 'partial'])"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 22,
   "id": "df073c73-1533-4749-88d0-b44f7ce1acaa",
   "metadata": {
    "tags": []
   },
   "outputs": [
    {
     "data": {
      "text/plain": [
       "ner_match_type\n",
       "tp     363\n",
       "fn      92\n",
       "fp      23\n",
       "be      22\n",
       "lbe     11\n",
       "Name: count, dtype: int64"
      ]
     },
     "execution_count": 22,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "ea = error_analysis(gt_test, pred_test_ds, tasks=['ner'])\n",
    "ea.ner_match_type.value_counts()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 23,
   "id": "e9f09e61-5987-463b-bf02-8b3db5056956",
   "metadata": {
    "tags": []
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>_word_len</th>\n",
       "      <th>_abbrev</th>\n",
       "      <th>gt_start</th>\n",
       "      <th>gt_end</th>\n",
       "      <th>gt_text</th>\n",
       "      <th>gold_type</th>\n",
       "      <th>pred_start</th>\n",
       "      <th>pred_end</th>\n",
       "      <th>pred_text</th>\n",
       "      <th>pred_type</th>\n",
       "      <th>ner_match_type</th>\n",
       "      <th>corpus_id</th>\n",
       "      <th>document_id</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>1.0</td>\n",
       "      <td>False</td>\n",
       "      <td>701.0</td>\n",
       "      <td>718.0</td>\n",
       "      <td>[18q-Alleelverlust]</td>\n",
       "      <td>Variant</td>\n",
       "      <td>NaN</td>\n",
       "      <td>NaN</td>\n",
       "      <td>None</td>\n",
       "      <td>None</td>\n",
       "      <td>fn</td>\n",
       "      <td>None</td>\n",
       "      <td>02_kolorektales-karzinom_0327.txt</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13</th>\n",
       "      <td>1.0</td>\n",
       "      <td>False</td>\n",
       "      <td>1414.0</td>\n",
       "      <td>1441.0</td>\n",
       "      <td>[Mikrosatelliteninstabilität]</td>\n",
       "      <td>Variant</td>\n",
       "      <td>NaN</td>\n",
       "      <td>NaN</td>\n",
       "      <td>None</td>\n",
       "      <td>None</td>\n",
       "      <td>fn</td>\n",
       "      <td>None</td>\n",
       "      <td>02_kolorektales-karzinom_0327.txt</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15</th>\n",
       "      <td>3.0</td>\n",
       "      <td>False</td>\n",
       "      <td>1621.0</td>\n",
       "      <td>1644.0</td>\n",
       "      <td>[Mismatch Repair Protein]</td>\n",
       "      <td>Gene or Protein</td>\n",
       "      <td>NaN</td>\n",
       "      <td>NaN</td>\n",
       "      <td>None</td>\n",
       "      <td>None</td>\n",
       "      <td>fn</td>\n",
       "      <td>None</td>\n",
       "      <td>02_kolorektales-karzinom_0327.txt</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16</th>\n",
       "      <td>1.0</td>\n",
       "      <td>True</td>\n",
       "      <td>1646.0</td>\n",
       "      <td>1650.0</td>\n",
       "      <td>[MMRP]</td>\n",
       "      <td>Gene or Protein</td>\n",
       "      <td>NaN</td>\n",
       "      <td>NaN</td>\n",
       "      <td>None</td>\n",
       "      <td>None</td>\n",
       "      <td>fn</td>\n",
       "      <td>None</td>\n",
       "      <td>02_kolorektales-karzinom_0327.txt</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17</th>\n",
       "      <td>1.0</td>\n",
       "      <td>True</td>\n",
       "      <td>1732.0</td>\n",
       "      <td>1736.0</td>\n",
       "      <td>[MMRP]</td>\n",
       "      <td>Gene or Protein</td>\n",
       "      <td>NaN</td>\n",
       "      <td>NaN</td>\n",
       "      <td>None</td>\n",
       "      <td>None</td>\n",
       "      <td>fn</td>\n",
       "      <td>None</td>\n",
       "      <td>02_kolorektales-karzinom_0327.txt</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>...</th>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>479</th>\n",
       "      <td>1.0</td>\n",
       "      <td>False</td>\n",
       "      <td>20458.0</td>\n",
       "      <td>20463.0</td>\n",
       "      <td>[MnSOD]</td>\n",
       "      <td>Gene or Protein</td>\n",
       "      <td>NaN</td>\n",
       "      <td>NaN</td>\n",
       "      <td>None</td>\n",
       "      <td>None</td>\n",
       "      <td>fn</td>\n",
       "      <td>None</td>\n",
       "      <td>28_komplementaermedizin_0272.txt</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>480</th>\n",
       "      <td>1.0</td>\n",
       "      <td>True</td>\n",
       "      <td>20582.0</td>\n",
       "      <td>20587.0</td>\n",
       "      <td>[PSADT]</td>\n",
       "      <td>Gene or Protein</td>\n",
       "      <td>NaN</td>\n",
       "      <td>NaN</td>\n",
       "      <td>None</td>\n",
       "      <td>None</td>\n",
       "      <td>fn</td>\n",
       "      <td>None</td>\n",
       "      <td>28_komplementaermedizin_0272.txt</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>481</th>\n",
       "      <td>1.0</td>\n",
       "      <td>True</td>\n",
       "      <td>20729.0</td>\n",
       "      <td>20734.0</td>\n",
       "      <td>[PSADT]</td>\n",
       "      <td>Gene or Protein</td>\n",
       "      <td>NaN</td>\n",
       "      <td>NaN</td>\n",
       "      <td>None</td>\n",
       "      <td>None</td>\n",
       "      <td>fn</td>\n",
       "      <td>None</td>\n",
       "      <td>28_komplementaermedizin_0272.txt</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>495</th>\n",
       "      <td>7.0</td>\n",
       "      <td>False</td>\n",
       "      <td>292.0</td>\n",
       "      <td>357.0</td>\n",
       "      <td>[genetisches Rearrangement der Anaplastischen ...</td>\n",
       "      <td>Variant</td>\n",
       "      <td>NaN</td>\n",
       "      <td>NaN</td>\n",
       "      <td>None</td>\n",
       "      <td>None</td>\n",
       "      <td>fn</td>\n",
       "      <td>None</td>\n",
       "      <td>29_adulte-weichgewebesarkome_0393.txt</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>504</th>\n",
       "      <td>1.0</td>\n",
       "      <td>False</td>\n",
       "      <td>134.0</td>\n",
       "      <td>139.0</td>\n",
       "      <td>[Aktin]</td>\n",
       "      <td>Gene or Protein</td>\n",
       "      <td>NaN</td>\n",
       "      <td>NaN</td>\n",
       "      <td>None</td>\n",
       "      <td>None</td>\n",
       "      <td>fn</td>\n",
       "      <td>None</td>\n",
       "      <td>29_adulte-weichgewebesarkome_0394.txt</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "<p>92 rows × 13 columns</p>\n",
       "</div>"
      ],
      "text/plain": [
       "     _word_len _abbrev  gt_start   gt_end  \\\n",
       "10         1.0   False     701.0    718.0   \n",
       "13         1.0   False    1414.0   1441.0   \n",
       "15         3.0   False    1621.0   1644.0   \n",
       "16         1.0    True    1646.0   1650.0   \n",
       "17         1.0    True    1732.0   1736.0   \n",
       "..         ...     ...       ...      ...   \n",
       "479        1.0   False   20458.0  20463.0   \n",
       "480        1.0    True   20582.0  20587.0   \n",
       "481        1.0    True   20729.0  20734.0   \n",
       "495        7.0   False     292.0    357.0   \n",
       "504        1.0   False     134.0    139.0   \n",
       "\n",
       "                                               gt_text        gold_type  \\\n",
       "10                                 [18q-Alleelverlust]          Variant   \n",
       "13                       [Mikrosatelliteninstabilität]          Variant   \n",
       "15                           [Mismatch Repair Protein]  Gene or Protein   \n",
       "16                                              [MMRP]  Gene or Protein   \n",
       "17                                              [MMRP]  Gene or Protein   \n",
       "..                                                 ...              ...   \n",
       "479                                            [MnSOD]  Gene or Protein   \n",
       "480                                            [PSADT]  Gene or Protein   \n",
       "481                                            [PSADT]  Gene or Protein   \n",
       "495  [genetisches Rearrangement der Anaplastischen ...          Variant   \n",
       "504                                            [Aktin]  Gene or Protein   \n",
       "\n",
       "     pred_start  pred_end pred_text pred_type ner_match_type corpus_id  \\\n",
       "10          NaN       NaN      None      None             fn      None   \n",
       "13          NaN       NaN      None      None             fn      None   \n",
       "15          NaN       NaN      None      None             fn      None   \n",
       "16          NaN       NaN      None      None             fn      None   \n",
       "17          NaN       NaN      None      None             fn      None   \n",
       "..          ...       ...       ...       ...            ...       ...   \n",
       "479         NaN       NaN      None      None             fn      None   \n",
       "480         NaN       NaN      None      None             fn      None   \n",
       "481         NaN       NaN      None      None             fn      None   \n",
       "495         NaN       NaN      None      None             fn      None   \n",
       "504         NaN       NaN      None      None             fn      None   \n",
       "\n",
       "                               document_id  \n",
       "10       02_kolorektales-karzinom_0327.txt  \n",
       "13       02_kolorektales-karzinom_0327.txt  \n",
       "15       02_kolorektales-karzinom_0327.txt  \n",
       "16       02_kolorektales-karzinom_0327.txt  \n",
       "17       02_kolorektales-karzinom_0327.txt  \n",
       "..                                     ...  \n",
       "479       28_komplementaermedizin_0272.txt  \n",
       "480       28_komplementaermedizin_0272.txt  \n",
       "481       28_komplementaermedizin_0272.txt  \n",
       "495  29_adulte-weichgewebesarkome_0393.txt  \n",
       "504  29_adulte-weichgewebesarkome_0394.txt  \n",
       "\n",
       "[92 rows x 13 columns]"
      ]
     },
     "execution_count": 23,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "ea.query('ner_match_type == \"fn\"')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 24,
   "id": "61e080ee-c02c-457f-bd9d-edfbca828c9d",
   "metadata": {
    "tags": []
   },
   "outputs": [],
   "source": [
    "mol_path_1 = \"\"\"\n",
    "Im Panel werden folgende Gene ganz oder teilweise untersucht:\n",
    " \n",
    " A) Amplicon-basierter Nachweis von DNA-Varianten in Mutationshotspots in folgenden Genen:\n",
    " AKT1, AKT2, AKT3, ALK, AR, ARAF, AXL, BRAF, BTK, CBL, CCND1, CDK4, CDK6, CHEK2, CSF1R, CTNNB1, DDR2, EGFR, ERBB3, ERBB2, ERBB4, ERCC2, ESR1, EZH2, FGFR1, FGFR2, FGFR3, FGFR4, FLT3, FOXL2, GATA2, GNA11, GNAQ, GNAS, H3F3A, HIST1H3B, HNF1A, HRAS, IDH1, IDH2, JAK1, JAK2, JAK3, KDR, KIT, KNSTRN, KRAS, MAGOH, MAP2K1, MAP2K2, MAP2K4, MAPK1, MAX, MDM4, MED12, MET, MTOR, MYC, MYCN, MYD88, NFE2L2, NRAS, NTRK1, NTRK2, PDGFRA, PDGFRB, PIK3CA, PIK3CB, PPP2R1A, PTPN11, RAC1, RAF1, RET, RHEB, RHOA, ROS1, SF3B1, SMAD4, SMO, SPOP, SRC, STAT3, TERT, TOP1, U2AF1, XPO1\n",
    " \n",
    " B) Amplicon-basierter Nachweis von DNA-Varianten in der kompletten kodierenden Sequenz in folgenden Genen:\n",
    " ARID1A, ATM, ATR, ATRX, BAP1, BRCA1, BRCA2, CDK12, CDKN1B, CDKN2A, CDKN2B, CHEK1, CREBBP, FANCA, FANCD2, FANCI, FBXW7, MLH1, MRE11A, MSH2, MSH6, NBN, NF1, NF2, NOTCH1, NOTCH2, NOTCH3, PALB2, PIK3R1, PMS2, POLE, PTCH1, PTEN, RAD50, RAD51, RAD51B, RAD51C, RAD51D, RB1, RNF43, SETD2, SLX4, SMARCA4, SMARCB1, STK11, TP53, TSC1, TSC2\n",
    " \n",
    " C) Amplicon-basierter  Nachweis von Änderungen der Genkopienzahl in folgenden Genen:\n",
    " AKT1, AKT2, AKT3, ALK, AR, AXL, BRAF, CCND1, CCND2, CCND3, CCNE1, CDK2, CDK4, CDK6, CDKN2A, CDKN2B, EGFR, ERBB2, ESR1, FGF19, FGF3, FGFR1, FGFR2, FGFR3, FGFR4, FLT3, IGF1R, KIT, KRAS, MDM2, MDM4, MET, MYC, MYCL, MYCN, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PIK3CA, PIK3CB, PPARG, RICTOR, TERT, TSC1, TSC2\n",
    " Pathologisch-anatomische Begutachtung:\n",
    " I. Eine Gallenblase mit mäßiger chronischer und florider Entzündung.\n",
    "\"\"\""
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 25,
   "id": "351b2f57-96f4-4bec-a3ae-d05847c9cd36",
   "metadata": {
    "tags": []
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<span class=\"tex2jax_ignore\"><div class=\"spans\" style=\"line-height: 2.5; direction: ltr\">\n",
       " Im Panel werden folgende Gene ganz oder teilweise untersucht : \n",
       " \n",
       "  A ) Amplicon - basierter Nachweis von DNA - Varianten in Mutationshotspots in folgenden Genen : \n",
       "  \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 77px;\">\n",
       "    AKT1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    AKT2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    AKT3\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    ALK\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    AR\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    ARAF\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    AXL\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    BRAF\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    BTK\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CBL\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CCND1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CDK4\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CDK6\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CHEK2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CSF1R\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CTNNB1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    DDR2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    EGFR\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    ERBB3\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    ERBB2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    ERBB4\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    ERCC2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    ESR1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    EZH2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    FGFR1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    FGFR2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    FGFR3\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    FGFR4\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    FLT3\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    FOXL2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    GATA2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    GNA11\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    GNAQ\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    GNAS\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    H3F3A\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    HIST1H3B\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    HNF1A\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    HRAS\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    IDH1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    IDH2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    JAK1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    JAK2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    JAK3\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    KDR\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    KIT\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    KNSTRN\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    KRAS\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MAGOH\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MAP2K1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MAP2K2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MAP2K4\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MAPK1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MAX\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MDM4\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MED12\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MET\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MTOR\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MYC\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MYCN\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MYD88\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    NFE2L2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    NRAS\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    NTRK1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    NTRK2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PDGFRA\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PDGFRB\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PIK3CA\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PIK3CB\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PPP2R1A\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PTPN11\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    RAC1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    RAF1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    RET\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    RHEB\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    RHOA\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    ROS1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    SF3B1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    SMAD4\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    SMO\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    SPOP\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    SRC\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    STAT3\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    TERT\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    TOP1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    U2AF1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 77px;\">\n",
       "    XPO1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "\n",
       " \n",
       "  B ) Amplicon - basierter Nachweis von DNA - Varianten in der kompletten kodierenden Sequenz in folgenden Genen : \n",
       "  \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 77px;\">\n",
       "    ARID1A\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    ATM\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    ATR\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    ATRX\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    BAP1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    BRCA1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    BRCA2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CDK12\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CDKN1B\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CDKN2A\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CDKN2B\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CHEK1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CREBBP\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    FANCA\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    FANCD2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    FANCI\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    FBXW7\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MLH1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MRE11A\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MSH2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MSH6\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    NBN\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    NF1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    NF2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    NOTCH1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    NOTCH2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    NOTCH3\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PALB2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PIK3R1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PMS2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    POLE\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PTCH1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PTEN\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    RAD50\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    RAD51\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    RAD51B\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    RAD51C\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    RAD51D\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    RB1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    RNF43\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    SETD2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    SLX4\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    SMARCA4\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    SMARCB1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    STK11\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    TP53\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    TSC1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 77px;\">\n",
       "    TSC2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "\n",
       " \n",
       "  C ) Amplicon - basierter   Nachweis von Änderungen der Genkopienzahl in folgenden Genen : \n",
       "  \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 77px;\">\n",
       "    AKT1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    AKT2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    AKT3\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    ALK\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    AR\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    AXL\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    BRAF\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CCND1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CCND2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CCND3\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CCNE1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CDK2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CDK4\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CDK6\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CDKN2A\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CDKN2B\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    EGFR\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    ERBB2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    ESR1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    FGF19\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    FGF3\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    FGFR1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    FGFR2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    FGFR3\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    FGFR4\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    FLT3\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    IGF1R\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    KIT\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    KRAS\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MDM2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MDM4\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MET\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MYC\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MYCL\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    MYCN\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    NTRK1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    NTRK2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    NTRK3\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PDGFRA\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PDGFRB\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PIK3CA\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PIK3CB\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    PPARG\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    RICTOR\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    TERT\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    TSC1\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ", \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 77px;\">\n",
       "    TSC2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "\n",
       "  Pathologisch - anatomische Begutachtung : \n",
       "  I. Eine Gallenblase mit mäßiger chronischer und florider Entzündung . \n",
       " </div></span>"
      ],
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    "show(model(mol_path_1))"
   ]
  },
  {
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   "execution_count": 26,
   "id": "24c9c723-f8a3-4801-a0fe-40837ed82533",
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    {
     "data": {
      "text/html": [
       "<span class=\"tex2jax_ignore\"><div class=\"spans\" style=\"line-height: 2.5; direction: ltr\">\n",
       " \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 77px;\">\n",
       "    HER2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "- Statusbestimmung : \n",
       " Es kamen für den Genlocus 17q12 sowie für die Centromerregion des Chromosoms 17 ( \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CEP17\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ") spezifische Sonden zum Einsatz . \n",
       " Es wurden &gt; 50 Tumorzellkerne ausgezählt . \n",
       " Es zeigten sich ein bis drei Signale für 17q12 ( \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    HER2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "/ \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    neu\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       ") und ein bis drei Signale für \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CEP17.\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "Die \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    17q12\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "/ \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    CEP17\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "Ratio lag bei &lt; 2,0:1. \n",
       "\n",
       " Folgende Varianten wurden nachgewiesen : \n",
       " \n",
       " Gen Variante     Frequenz     Lesetiefe    Bewertung \n",
       "\n",
       " \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 111px;\">\n",
       "    KRAS\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 74px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 91px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 74px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "<span style=\"background: #ddd; top: 91px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "    chr12:25398284:NM_033360.4:Exon2:c.35G &gt; T :p . \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    G12V\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "8,7 %     2.235 \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    AMP\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "Tier I \n",
       "\n",
       " Aktivierende Hotspotmutation \n",
       "\n",
       " \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 111px;\">\n",
       "    JAK2\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 57px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 74px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "<span style=\"background: #ddd; top: 91px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 74px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "<span style=\"background: #ddd; top: 91px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "    chr9:5073770:NM_004972.4:Exon14:c.1849G &gt; T :p . V617F    20,4 %    831 \n",
       "<span style=\"font-weight: bold; display: inline-block; position: relative; height: 60px;\">\n",
       "    AMP\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "</span>\n",
       "\n",
       "    \n",
       "<span style=\"background: #ddd; top: 40px; height: 4px; border-top-left-radius: 3px; border-bottom-left-radius: 3px; left: -1px; width: calc(100% + 2px); position: absolute;\">\n",
       "    <span style=\"background: #ddd; z-index: 10; color: #000; top: -0.5em; padding: 2px 3px; position: absolute; font-size: 0.6em; font-weight: bold; line-height: 1; border-radius: 3px\">\n",
       "        Gene or Protein\n",
       "    </span>\n",
       "</span>\n",
       "\n",
       "\n",
       "</span>\n",
       "Tier I \n",
       "\n",
       " Aktivierende Hotspotmutation , möglicherweise aus den Blutgefäßen im Tumor . Ist eine P.vera oder MPN bekannt ? \n",
       " \n",
       " Kopienzahlveränderungen :     KEIN Anhalt für das Vorliegen einer Kopienzahlveränderung eines der aufgeführten Gene \n",
       " </div></span>"
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   "source": [
    "mol_path_2 = \"\"\"\n",
    "HER2-Statusbestimmung:\n",
    "Es kamen für den Genlocus 17q12 sowie für die Centromerregion des Chromosoms 17 (CEP17) spezifische Sonden zum Einsatz. \n",
    "Es wurden > 50 Tumorzellkerne ausgezählt. \n",
    "Es zeigten sich ein bis drei Signale für 17q12 (HER2/neu) und ein bis drei Signale für CEP17. Die 17q12/CEP17 Ratio lag bei < 2,0:1.\n",
    "\n",
    "Folgende Varianten wurden nachgewiesen:\n",
    " \n",
    "Gen Variante    Frequenz    Lesetiefe   Bewertung\n",
    "\n",
    "KRAS    chr12:25398284:NM_033360.4:Exon2:c.35G>T:p.G12V 8,7%    2.235 AMP Tier I\n",
    "\n",
    "Aktivierende Hotspotmutation\n",
    "\n",
    "JAK2    chr9:5073770:NM_004972.4:Exon14:c.1849G>T:p.V617F   20,4%   831 AMP Tier I\n",
    "\n",
    "Aktivierende Hotspotmutation, möglicherweise aus den Blutgefäßen im Tumor. Ist eine P.vera oder MPN bekannt?\n",
    " \n",
    "Kopienzahlveränderungen:    KEIN Anhalt für das Vorliegen einer Kopienzahlveränderung eines der aufgeführten Gene\n",
    "\"\"\"\n",
    "\n",
    "show(model(mol_path_2))"
   ]
  },
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