Irmasari Hafidz's documentation for the task JKU Junior Researcher Challenge 2018.
Create a browser-based JavaScript tool for interactive visualization of mutations in cancer.
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Retrieve data from an API provided by the Data Coordination Center of the International Cancer Genomics Consortium (http://dcc.icgc.org) & obtain mutation data for the Glioblastoma multiforme project (GBM-US) from the mutations API endpoint of the ICGC Data Coordination Center
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Retrieve:
- mutation ids,
- mutation details,
- the type of the mutation,
- chromosome,
- start and
- end position for 100 mutations of the GBM-US project.
The UI for the web browser should give information about:
- Type Overview: shows the number of mutations for each mutation type
- Chromosome Overview: shows the distribution of mutations across the 22 human autosome pairs plus the two sex chromosomes
The dataset is in JSON file. The JSON file is extracted from this link https://dcc.icgc.org/api/v1/projects/GBM-US/mutations?field=id,mutation,type,chromosome,start,end&size=100&order=desc
JSON example of the dataset:
1
id "MU588573"
type "single base substitution"
chromosome "7"
start 55221822
end 55221822
mutation "C>T"
study []