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jpquast committed Oct 21, 2024
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3 changes: 1 addition & 2 deletions R/calculate_protein_abundance.R
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#' intensities as the protein abundance. Another option is `"iq"`, which performs protein
#' quantification based on a maximal peptide ratio extraction algorithm that is adapted from the
#' MaxLFQ algorithm of the MaxQuant software. Functions from the
#' \href{https://academic.oup.com/bioinformatics/article/36/8/2611/5697917}{`iq`} package are
#' used. Default is `"iq"`.
#' `iq` package (\doi{10.1093/bioinformatics/btz961}) are used. Default is `"iq"`.
#' @param for_plot a logical value indicating whether the result should be only protein intensities
#' or protein intensities together with precursor intensities that can be used for plotting using
#' \code{peptide_profile_plot()}. Default is \code{FALSE}.
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8 changes: 4 additions & 4 deletions R/data.R
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#' @format A data frame containing peptide level data from a Spectronaut report.
#' @source Piazza, I., Beaton, N., Bruderer, R. et al. A machine learning-based chemoproteomic
#' approach to identify drug targets and binding sites in complex proteomes. Nat Commun 11, 4200
#' (2020). https://doi.org/10.1038/s41467-020-18071-x
#' (2020). \doi{10.1038/s41467-020-18071-x}
"rapamycin_10uM"

#' Rapamycin dose response example data
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#' @format A data frame containing peptide level data from a Spectronaut report.
#' @source Piazza, I., Beaton, N., Bruderer, R. et al. A machine learning-based chemoproteomic
#' approach to identify drug targets and binding sites in complex proteomes. Nat Commun 11, 4200
#' (2020). https://doi.org/10.1038/s41467-020-18071-x
#' (2020). \doi{10.1038/s41467-020-18071-x}
"rapamycin_dose_response"

#' Structural analysis example data
#'
#' Example data used for the vignette about structural analysis. The data was obtained from
#' \href{https://doi.org/10.1016/j.cell.2020.12.021}{Cappelletti 2021}
#' Cappelletti et al. 2021 (\doi{10.1016/j.cell.2020.12.021})
#' and corresponds to two separate experiments. Both experiments were limited proteolyis coupled to
#' mass spectrometry (LiP-MS) experiments conducted on purified proteins. The first protein is
#' phosphoglycerate kinase 1 (pgk) and it was treated with 25mM 3-phosphoglyceric acid (3PG).
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#' @source Cappelletti V, Hauser T, Piazza I, Pepelnjak M, Malinovska L, Fuhrer T, Li Y, Dörig C,
#' Boersema P, Gillet L, Grossbach J, Dugourd A, Saez-Rodriguez J, Beyer A, Zamboni N, Caflisch A,
#' de Souza N, Picotti P. Dynamic 3D proteomes reveal protein functional alterations at high
#' resolution in situ. Cell. 2021 Jan 21;184(2):545-559.e22. doi: 10.1016/j.cell.2020.12.021.
#' resolution in situ. Cell. 2021 Jan 21;184(2):545-559.e22. \doi{10.1016/j.cell.2020.12.021}.
#' Epub 2020 Dec 23. PMID: 33357446; PMCID: PMC7836100.
"ptsi_pgk"

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3 changes: 1 addition & 2 deletions R/fetch_eco.R
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#' essential to navigating the ever-growing (in size and complexity) corpus of scientific
#' information."
#'
#' More information can be found in their
#' \href{https://academic.oup.com/nar/article/47/D1/D1186/5165344}{publication}.
#' More information can be found in their publication (\doi{10.1093/nar/gky1036}).
#'
#' @param return_relation a logical value that indicates if relational information should be returned instead
#' the main descriptive information. This data can be used to check the relations of ECO terms to each other.
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3 changes: 1 addition & 2 deletions man/calculate_protein_abundance.Rd

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3 changes: 1 addition & 2 deletions man/fetch_eco.Rd

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4 changes: 2 additions & 2 deletions man/ptsi_pgk.Rd

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2 changes: 1 addition & 1 deletion man/rapamycin_10uM.Rd

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2 changes: 1 addition & 1 deletion man/rapamycin_dose_response.Rd

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