Skip to content

Releases: kids-first/kf-jointgenotyping-workflow

🔨📝 Non Prod Plink and Doc Updates

17 Sep 17:51
Compare
Choose a tag to compare

Non-prod tools added and documentation updated for clarity for small cohort joint genotyping workflow, including the following points:

  • It is a small cohort calling workflow, not a study-wide one, intended for trios mostly
  • It also follows best practices for WGS. WXS will follow in a later update
  • Documentation now describes workflow outputs

What's Changed

Full Changelog: v2.4.0...v2.4.1

💫 Refactor Annotation

16 Feb 14:53
Compare
Choose a tag to compare

To meet new standards:

  • CADD, InterVar, dbnsfp, ClinVar dropped as default/recommended annotations. They are now optional
  • gnomAD v3.1.1 annotation now done by ecthvar with custom fields added (see README here)
  • Germline git submodule replaced with more focused kf-annotation-tools

What's Changed

Full Changelog: v2.3.2...v2.4.0

📖 Updated Default Cavatica Refs

01 Feb 19:25
Compare
Choose a tag to compare

After exporting our default refs to a bucket, cavatica pointers were updated. Functionality of the app is not affected, except on cavatica, using an old version risks a couple files not being pulled in automatically.
Also upgraded submodule pointer to ensure correct version is being used compatible with the update.

What's Changed

  • 📖 Changed default reference location after export by @migbro in #39

Full Changelog: v2.3.1...v2.3.2

✏️ Set new default for tool name

07 Dec 18:36
Compare
Choose a tag to compare

To match the standard established by the single sample genotyping workflow, to satisfy ops harmonization requirements, we are updating the default file extension.

What's Changed

  • 🔧 Update default File Prefix by @migbro in #38

Full Changelog: v2.3.0...v2.3.1

💪 DNA Annotation Upgrade

06 Oct 19:54
Compare
Choose a tag to compare

This release is part of the overall effort to harmonize annotation sources used across all pipelines.
Following the path of the single sample genotyping workflow:

  • Added standalone wf with ability to strip old annotations to avoid conflicts and re-use old calls
  • Upgraded from VEP 93 to VEP 105
  • Incorporated workflow into single sample calling
  • Added updated gnomad, clinvar, and dbsnsfp and intervar references to enhance "off-the-shelf" usability for downstream germline users

What's Changed

Full Changelog: v2.2.3...v2.3.0

KFDRC Genotyping Production Workflow

12 Nov 21:10
Compare
Choose a tag to compare

What's Changed

Full Changelog: v2.2.2...v2.2.3

KFDRC Genotyping Production Workflow

06 Apr 14:29
Compare
Choose a tag to compare

Bug fix for suggested file ids.

KFDRC Genotyping Production Workflow

11 Feb 16:55
Compare
Choose a tag to compare

This release updates the docker being pulled for peddy from using latest to being pinned to peddy v0.4.2. This is functionally equivalent to v2.2.0.

KFDRC Genotyping Production Workflow

02 Nov 17:16
Compare
Choose a tag to compare

This release updates the dockerPulls for all tools that were using a DockerHub registry.

KFDRC Genotyping Production Workflow

18 Sep 20:25
Compare
Choose a tag to compare

This release fixes a bug in the public app where files were pointing to non-public file ID's.