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R code to calculate required sample size [& simulated power] for (1) prognostic [using Schoenfeld; Rubinstein; Factor-of-4 methods] and (2) predictive biomarker studies [using Schmoor; Peterson and George; Factor-of-16 methods] for survival data. Use files below to create R scripts & load functions; see examples at bottom of file.

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kristenmay206/BiomarkerStudySS

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R code to calculate required sample size [& simulated power] for (1) prognostic [using Schoenfeld; Rubinstein; Factor-of-4 methods] and (2) predictive biomarker studies [using Schmoor; Peterson and George; Factor-of-16 methods] for survival data. Use files below to create R scripts & load functions; see examples at bottom of file.

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