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Update README.md
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liliw-w authored Jan 31, 2024
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Expand Up @@ -14,8 +14,11 @@ Trans-PCO allows the use of many types of gene groups or sets. For example, gene



![](docs/pipeline.png){width=60%}
<p align="center">
<img src="docs/pipeline.png" width="800" />
</p>

Figure: Three main steps in trans-PCO pipeline. The first step of trans-PCO pre-processes RNA-seq data to reduce false positive trans-eQTL associations due to read alignment errors. The second step involves grouping genes into gene sets, such as co-expression modules or biological pathways. The last step tests for trans-eQTLs of each gene set by a PC-based multivariate association test.

<img src="docs/pipeline.png" width="800">


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