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DESCRIPTION
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DESCRIPTION
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Package: spillR
Type: Package
Title: Spillover Compensation in Mass Cytometry Data
Version: 1.1.2
Authors@R: c(
person("Marco", "Guazzini",
email= "m.guazzini@student.maastrichtuniversity.nl",
role = c("aut", "cre"), comment = c(ORCID = "0009-0007-8111-5772")),
person("Alexander G.", "Reisach" ,
email = "alexander.reisach@u-paris.fr",
role = "aut", comment = c(ORCID = "0009-0003-5057-6278")),
person("Sebastian", "Weichwald",
email = "sweichwald@math.ku.dk",
role = "aut", comment = c(ORCID = "0000-0003-0169-7244")),
person("Christof", "Seiler",
email = "christof.seiler@maastrichtuniversity.nl",
role = "aut", comment = c(ORCID = "0000-0001-8802-3642")))
Description: Channel interference in mass cytometry can cause spillover
and may result in miscounting of protein markers. We develop a
nonparametric finite mixture model and use the mixture components
to estimate the probability of spillover. We implement our method
using expectation-maximization to fit the mixture model.
biocViews:
FlowCytometry,
ImmunoOncology,
MassSpectrometry,
Preprocessing,
SingleCell,
Software,
StatisticalMethod,
Visualization,
Regression
License: LGPL-3
Encoding: UTF-8
LazyData: false
Config/testthat/edition: 3
RoxygenNote: 7.3.1
Imports:
dplyr,
tibble,
tidyselect,
stats,
ggplot2,
tidyr,
spatstat.univar,
S4Vectors,
parallel
Depends:
R (>= 4.3.0),
SummarizedExperiment,
CATALYST
Suggests:
knitr,
rmarkdown,
cowplot,
testthat (>= 3.0.0),
BiocStyle,
hexbin
VignetteBuilder: knitr