diff --git a/mavlink-core/Cargo.toml b/mavlink-core/Cargo.toml
index 5bf97b903c..75f4f449f5 100644
--- a/mavlink-core/Cargo.toml
+++ b/mavlink-core/Cargo.toml
@@ -29,6 +29,7 @@ serial = { version = "0.4", optional = true }
 tokio = { version = "1.0", default-features = false, features = ["io-util", "net", "sync", "fs"], optional = true }
 sha2 = { version = "0.10", optional = true }
 async-trait = { version = "0.1.18", optional = true }
+tokio-serial = { version = "5.4.4", default-features = false, optional = true }
 
 [features]
 "std" = ["byteorder/std"]
@@ -41,7 +42,7 @@ async-trait = { version = "0.1.18", optional = true }
 "embedded" = ["dep:embedded-io", "dep:embedded-io-async"]
 "embedded-hal-02" = ["dep:nb", "dep:embedded-hal-02"]
 "serde" = ["dep:serde", "dep:serde_arrays"]
-"tokio-1" = ["dep:tokio", "dep:async-trait"]
+"tokio-1" = ["dep:tokio", "dep:async-trait", "dep:tokio-serial"]
 "signing" = ["dep:sha2"]
 default = ["std", "tcp", "udp", "direct-serial", "serde"]
 
diff --git a/mavlink-core/src/async_connection/direct_serial.rs b/mavlink-core/src/async_connection/direct_serial.rs
new file mode 100644
index 0000000000..3edd6f2c12
--- /dev/null
+++ b/mavlink-core/src/async_connection/direct_serial.rs
@@ -0,0 +1,121 @@
+//! Async Serial MAVLINK connection
+
+use core::ops::DerefMut;
+use std::io;
+
+use tokio::sync::Mutex;
+use tokio_serial::{SerialPort, SerialPortBuilderExt, SerialStream};
+
+use crate::{
+    async_peek_reader::AsyncPeekReader, read_versioned_msg_async_signed,
+    write_versioned_msg_async_signed, MavHeader, MavlinkVersion, Message,
+};
+
+#[cfg(not(feature = "signing"))]
+use crate::{read_versioned_msg, write_versioned_msg};
+#[cfg(feature = "signing")]
+use crate::{SigningConfig, SigningData};
+
+use super::AsyncMavConnection;
+
+pub fn open(settings: &str) -> io::Result<AsyncSerialConnection> {
+    let settings_toks: Vec<&str> = settings.split(':').collect();
+    if settings_toks.len() < 2 {
+        return Err(io::Error::new(
+            io::ErrorKind::AddrNotAvailable,
+            "Incomplete port settings",
+        ));
+    }
+
+    let Ok(baud) = settings_toks[1].parse::<u32>() else {
+        return Err(io::Error::new(
+            io::ErrorKind::AddrNotAvailable,
+            "Invalid baud rate",
+        ));
+    };
+
+    let port_name = settings_toks[0];
+    let mut port = tokio_serial::new(port_name, baud).open_native_async()?;
+    port.set_data_bits(tokio_serial::DataBits::Eight)?;
+    port.set_parity(tokio_serial::Parity::None)?;
+    port.set_stop_bits(tokio_serial::StopBits::One)?;
+    port.set_flow_control(tokio_serial::FlowControl::None)?;
+
+    Ok(AsyncSerialConnection {
+        port: Mutex::new(AsyncPeekReader::new(port)),
+        sequence: Mutex::new(0),
+        protocol_version: MavlinkVersion::V2,
+        #[cfg(feature = "signing")]
+        signing_data: None,
+    })
+}
+
+pub struct AsyncSerialConnection {
+    port: Mutex<AsyncPeekReader<SerialStream>>,
+    sequence: Mutex<u8>,
+    protocol_version: MavlinkVersion,
+    #[cfg(feature = "signing")]
+    signing_data: Option<SigningData>,
+}
+
+#[async_trait::async_trait]
+impl<M: Message + Sync + Send> AsyncMavConnection<M> for AsyncSerialConnection {
+    async fn recv(&self) -> Result<(MavHeader, M), crate::error::MessageReadError> {
+        let mut port = self.port.lock().await;
+        
+        #[cfg(not(feature = "signing"))]
+        let result = read_versioned_msg_async(port.deref_mut(), self.protocol_version).await;
+        #[cfg(feature = "signing")]
+        let result = read_versioned_msg_async_signed(
+            port.deref_mut(),
+            self.protocol_version,
+            self.signing_data.as_ref(),
+        )
+        .await;
+        result
+    }
+
+    async fn send(
+        &self,
+        header: &MavHeader,
+        data: &M,
+    ) -> Result<usize, crate::error::MessageWriteError> {
+        let mut port = self.port.lock().await;
+        let mut sequence = self.sequence.lock().await;
+
+        let header = MavHeader {
+            sequence: *sequence,
+            system_id: header.system_id,
+            component_id: header.component_id,
+        };
+
+        *sequence = sequence.wrapping_add(1);
+
+        #[cfg(not(feature = "signing"))]
+        let result =
+            write_versioned_msg_async(port.reader_mut(), self.protocol_version, header, data).await;
+        #[cfg(feature = "signing")]
+        let result = write_versioned_msg_async_signed(
+            port.reader_mut(),
+            self.protocol_version,
+            header,
+            data,
+            self.signing_data.as_ref(),
+        )
+        .await;
+        result
+    }
+
+    fn set_protocol_version(&mut self, version: MavlinkVersion) {
+        self.protocol_version = version;
+    }
+
+    fn get_protocol_version(&self) -> MavlinkVersion {
+        self.protocol_version
+    }
+
+    #[cfg(feature = "signing")]
+    fn setup_signing(&mut self, signing_data: Option<SigningConfig>) {
+        self.signing_data = signing_data.map(SigningData::from_config)
+    }
+}
diff --git a/mavlink-core/src/async_connection/mod.rs b/mavlink-core/src/async_connection/mod.rs
index 35e2fa0e78..b9c1f7d053 100644
--- a/mavlink-core/src/async_connection/mod.rs
+++ b/mavlink-core/src/async_connection/mod.rs
@@ -8,6 +8,9 @@ mod tcp;
 #[cfg(feature = "udp")]
 mod udp;
 
+#[cfg(feature = "direct-serial")]
+mod direct_serial;
+
 mod file;
 
 #[cfg(feature = "signing")]