diff --git a/src/ontology/dron.Makefile b/src/ontology/dron.Makefile index d520eec..cffc0a9 100644 --- a/src/ontology/dron.Makefile +++ b/src/ontology/dron.Makefile @@ -24,7 +24,7 @@ $(IMPORTDIR)/uo_import.owl: $(MIRRORDIR)/uo.owl $(IMPORTDIR)/uo_terms_combined.t # (no NDC) and the run a regular full release. LITE_ARTEFACTS=$(COMPONENTSDIR)/dron-rxnorm.owl $(COMPONENTSDIR)/dron-ingredient.owl $(COMPONENTSDIR)/dron-obsolete.owl $(IMPORT_OWL_FILES) -$(TMPDIR)/dron-edit_lite.owl: $(SRC) $(LITE_ARTEFACTS) +$(TMPDIR)/dron-edit_lite.owl: $(SRC) $(LITE_ARTEFACTS) | $(TMPDIR)/ $(ROBOT) remove --input $(SRC) --select imports \ merge $(patsubst %, -i %, $(LITE_ARTEFACTS)) --output $@.tmp.owl && mv $@.tmp.owl $@ @@ -45,7 +45,7 @@ $(TMPDIR)/ldtab.jar: | $(TMPDIR) LDTAB := java -jar $(TMPDIR)/ldtab.jar # Load DrOn templates into SQLite. -$(TMPDIR)/dron.db: $(SCRIPTSDIR)/create-dron-tables.sql $(SCRIPTSDIR)/load-dron-tables.sql $(SCRIPTSDIR)/index-dron-tables.sql $(TEMPLATEDIR)/*.tsv +$(TMPDIR)/dron.db: $(SCRIPTSDIR)/create-dron-tables.sql $(SCRIPTSDIR)/load-dron-tables.sql $(SCRIPTSDIR)/index-dron-tables.sql $(TEMPLATEDIR)/*.tsv | $(TMPDIR)/ rm -f $@ sqlite3 $@ < $< sqlite3 $@ < $(word 2,$^) diff --git a/src/scripts/create-dron-tables.sql b/src/scripts/create-dron-tables.sql index a5fec03..e6e44aa 100644 --- a/src/scripts/create-dron-tables.sql +++ b/src/scripts/create-dron-tables.sql @@ -113,6 +113,12 @@ CREATE TABLE unit ( ontology_label TEXT UNIQUE NOT NULL ); +CREATE TABLE dose_form ( + rxcui INTEGER PRIMARY KEY NOT NULL, + label TEXT UNIQUE NOT NULL, + curie TEXT NOT NULL +); + -- Create triggers for automatically assigning DRON IDs. -- First create a table with one row to track the current ID. CREATE TABLE current_dron_id ( id INTEGER ); diff --git a/src/scripts/load-dron-tables.sql b/src/scripts/load-dron-tables.sql index ea7146e..7e4b329 100644 --- a/src/scripts/load-dron-tables.sql +++ b/src/scripts/load-dron-tables.sql @@ -20,6 +20,7 @@ PRAGMA foreign_keys = ON; .import --skip 1 ../templates/ndc_clinical_drug.tsv ndc_clinical_drug .import --skip 1 ../templates/obsolete.tsv obsolete .import --skip 1 ../templates/unit.tsv unit +.import --skip 1 ../templates/dose_form.tsv dose_form -- Set current_dron_id. DELETE FROM current_dron_id; diff --git a/src/scripts/update-dron-from-rxnorm.sql b/src/scripts/update-dron-from-rxnorm.sql index e967c7f..bd95e6e 100644 --- a/src/scripts/update-dron-from-rxnorm.sql +++ b/src/scripts/update-dron-from-rxnorm.sql @@ -11,11 +11,15 @@ DROP TABLE IF EXISTS new_clinical_drug_form; CREATE TABLE new_clinical_drug_form AS SELECT RXCUI AS rxcui, - STR AS label -FROM rxnorm.RXNCONSO -WHERE SAB = 'RXNORM' - AND TTY = 'SCDF' - AND RXCUI NOT IN (SELECT rxcui FROM dron.clinical_drug_form); + STR AS label, + COALESCE(df.curie, 'DRON:00000005') AS parent -- default 'drug product' +FROM rxnorm.RXNCONSO AS c +LEFT JOIN rxnorm.RXNREL AS r ON r.RXCUI2 = c.RXCUI +LEFT JOIN dron.dose_form AS df ON r.RXCUI1 = df.rxcui +WHERE c.SAB = 'RXNORM' + AND c.TTY = 'SCDF' + AND c.RXCUI NOT IN (SELECT rxcui FROM dron.clinical_drug_form) + AND r.RELA = 'has_dose_form'; -- Find new clinical drugs. DROP TABLE IF EXISTS new_clinical_drug; @@ -120,7 +124,7 @@ INSERT INTO dron.clinical_drug_form SELECT NULL AS curie, label AS label, - NULL AS parent, + parent AS parent, rxcui AS rxcui FROM new_clinical_drug_form; diff --git a/src/templates/clinical_drug_form.tsv b/src/templates/clinical_drug_form.tsv index 73cd941..0189892 100644 --- a/src/templates/clinical_drug_form.tsv +++ b/src/templates/clinical_drug_form.tsv @@ -16954,93 +16954,93 @@ DRON:01001217 zuranolone Oral Capsule DRON:00000026 2669909 DRON:01001218 benzocaine / isopropyl alcohol / menthol Medicated Pad DRON:00000005 2667819 DRON:01001219 talquetamab Injection DRON:00000005 2644451 DRON:01001220 cipaglucosidase alfa Injection DRON:00000005 2667437 -DRON:01002961 influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Suspension 1427025 -DRON:01002962 influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe 1427036 -DRON:01002963 Streptococcus pneumoniae type 1 capsular polysaccharide antigen / Streptococcus pneumoniae type 10A capsular polysaccharide antigen / Streptococcus pneumoniae type 11A capsular polysaccharide antigen / Streptococcus pneumoniae type 12F capsular polysaccharide antigen / Streptococcus pneumoniae type 14 capsular polysaccharide antigen / Streptococcus pneumoniae type 15B capsular polysaccharide antigen / Streptococcus pneumoniae type 17F capsular polysaccharide antigen / Streptococcus pneumoniae type 18C capsular polysaccharide antigen / Streptococcus pneumoniae type 19A capsular polysaccharide antigen / Streptococcus pneumoniae type 19F capsular polysaccharide antigen / Streptococcus pneumoniae type 2 capsular polysaccharide antigen / Streptococcus pneumoniae type 20 capsular polysaccharide antigen / Streptococcus pneumoniae type 22F capsular polysaccharide antigen / Streptococcus pneumoniae type 23F capsular polysaccharide antigen / Streptococcus pneumoniae type 3 capsular polysaccharide antigen / Streptococcus pneumoniae type 33F capsular polysaccharide antigen / Streptococcus pneumoniae type 4 capsular polysaccharide antigen / Streptococcus pneumoniae type 5 capsular polysaccharide antigen / Streptococcus pneumoniae type 6B capsular polysaccharide antigen / Streptococcus pneumoniae type 7F capsular polysaccharide antigen / Streptococcus pneumoniae type 8 capsular polysaccharide antigen / Streptococcus pneumoniae type 9N capsular polysaccharide antigen / Streptococcus pneumoniae type 9V capsular polysaccharide antigen Prefilled Syringe 1547579 -DRON:01002964 L1 protein, human papillomavirus type 11 vaccine / L1 protein, human papillomavirus type 16 vaccine / L1 protein, human papillomavirus type 18 vaccine / L1 protein, human papillomavirus type 31 vaccine / L1 protein, human papillomavirus type 33 vaccine / L1 protein, human papillomavirus type 45 vaccine / L1 protein, human papillomavirus type 52 vaccine / L1 protein, human papillomavirus type 58 vaccine / L1 protein, human papillomavirus type 6 vaccine Prefilled Syringe 1597100 -DRON:01002965 L1 protein, human papillomavirus type 11 vaccine / L1 protein, human papillomavirus type 16 vaccine / L1 protein, human papillomavirus type 18 vaccine / L1 protein, human papillomavirus type 31 vaccine / L1 protein, human papillomavirus type 33 vaccine / L1 protein, human papillomavirus type 45 vaccine / L1 protein, human papillomavirus type 52 vaccine / L1 protein, human papillomavirus type 58 vaccine / L1 protein, human papillomavirus type 6 vaccine Injection 1656973 -DRON:01002966 Neisseria meningitidis serogroup A oligosaccharide diphtheria CRM197 protein conjugate vaccine / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine / Neisseria meningitidis serogroup W-135 oligosaccharide diphtheria CRM197 protein conjugate vaccine / Neisseria meningitidis serogroup Y oligosaccharide diphtheria CRM197 protein conjugate vaccine Injection 1657353 -DRON:01002967 acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Injection 1657394 -DRON:01002968 acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Injection 1657429 -DRON:01002969 Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine Injection 1657443 -DRON:01002970 Streptococcus pneumoniae type 1 capsular polysaccharide antigen / Streptococcus pneumoniae type 10A capsular polysaccharide antigen / Streptococcus pneumoniae type 11A capsular polysaccharide antigen / Streptococcus pneumoniae type 12F capsular polysaccharide antigen / Streptococcus pneumoniae type 14 capsular polysaccharide antigen / Streptococcus pneumoniae type 15B capsular polysaccharide antigen / Streptococcus pneumoniae type 17F capsular polysaccharide antigen / Streptococcus pneumoniae type 18C capsular polysaccharide antigen / Streptococcus pneumoniae type 19A capsular polysaccharide antigen / Streptococcus pneumoniae type 19F capsular polysaccharide antigen / Streptococcus pneumoniae type 2 capsular polysaccharide antigen / Streptococcus pneumoniae type 20 capsular polysaccharide antigen / Streptococcus pneumoniae type 22F capsular polysaccharide antigen / Streptococcus pneumoniae type 23F capsular polysaccharide antigen / Streptococcus pneumoniae type 3 capsular polysaccharide antigen / Streptococcus pneumoniae type 33F capsular polysaccharide antigen / Streptococcus pneumoniae type 4 capsular polysaccharide antigen / Streptococcus pneumoniae type 5 capsular polysaccharide antigen / Streptococcus pneumoniae type 6B capsular polysaccharide antigen / Streptococcus pneumoniae type 7F capsular polysaccharide antigen / Streptococcus pneumoniae type 8 capsular polysaccharide antigen / Streptococcus pneumoniae type 9N capsular polysaccharide antigen / Streptococcus pneumoniae type 9V capsular polysaccharide antigen Injection 1658469 -DRON:01002971 aspirin / calcium carbonate Oral Tablet 1722688 -DRON:01002972 botulinum neurotoxin A immune FAB2 / botulinum neurotoxin B immune FAB2 / botulinum neurotoxin C immune FAB2 / botulinum neurotoxin D immune FAB2 / botulinum neurotoxin E immune FAB2 / botulinum neurotoxin F immune FAB2 / botulinum neurotoxin G immune FAB2 Injection 1722717 -DRON:01002973 heparin Injectable Solution 1856275 -DRON:01002974 heparin Prefilled Syringe 1856278 -DRON:01002975 glutamine Powder for Oral Solution 1869683 -DRON:01002976 ropivacaine Prefilled Syringe 1996290 -DRON:01002977 gemcitabine Injectable Solution 1998782 -DRON:01002978 cefepime Injectable Solution 2058952 -DRON:01002979 acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine / hepatitis B surface antigen vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Injection 2109613 -DRON:01002980 thyrotropin alfa Injection 2166571 -DRON:01002981 acetaminophen / chlorpheniramine / phenylephrine Oral Solution 2178940 -DRON:01002982 glucagon Prefilled Syringe 2199309 -DRON:01002983 zinc sulfate Injectable Solution 2201520 -DRON:01002984 ethanol / iodine / sodium iodide Topical Solution 2265290 -DRON:01002985 Atlantic halibut allergenic extract Injectable Solution 2274704 -DRON:01002986 amphotericin B Injectable Solution 2285811 -DRON:01002987 Neisseria meningitidis serogroup A capsular polysaccharide tetanus toxoid protein conjugate vaccine / Neisseria meningitidis serogroup C capsular polysaccharide tetanus toxoid protein conjugate vaccine / Neisseria meningitidis serogroup W-135 capsular polysaccharide tetanus toxoid protein conjugate vaccine / Neisseria meningitidis serogroup Y capsular polysaccharide tetanus toxoid protein conjugate vaccine Injection 2360581 -DRON:01002988 acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine / hepatitis B surface antigen vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Prefilled Syringe 2468236 -DRON:01002989 oxymetazoline Nasal Gel 2474263 -DRON:01002990 fentanyl Prefilled Syringe 2474266 -DRON:01002991 Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 10A capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 11A capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 12F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 15B capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 22F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 33F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 8 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine Prefilled Syringe 2566307 -DRON:01002992 Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 22F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 33F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine Prefilled Syringe 2566415 -DRON:01002993 dextromethorphan / doxylamine / phenylephrine Oral Solution 2566813 -DRON:01002994 glycerin Topical Gel 2586848 -DRON:01002995 pemetrexed Injectable Solution 2590671 -DRON:01002996 succinylcholine Prefilled Syringe 2598127 -DRON:01002997 labetalol Prefilled Syringe 2598342 -DRON:01002998 dotatate Injection 2599510 -DRON:01002999 doramectin / levamisole Injectable Solution 2611785 -DRON:01003000 abametapir Topical Lotion 2618847 -DRON:01003001 risdiplam Oral Solution 2618856 -DRON:01003002 Bifidobacterium infantis Chewable Tablet 2618885 -DRON:01003003 Bifidobacterium infantis Oral Capsule 2618892 -DRON:01003004 Bifidobacterium infantis Powder for Oral Suspension 2618901 -DRON:01003005 clascoterone Topical Cream 2618910 -DRON:01003006 casimersen Injection 2618918 -DRON:01003007 rimegepant Disintegrating Oral Tablet 2618951 -DRON:01003008 oliceridine Injection 2618959 -DRON:01003009 Bifidobacterium infantis Oral Powder 2619040 -DRON:01003010 teprotumumab Injection 2619146 -DRON:01003011 omeprazole / sodium bicarbonate Oral Suspension 2625143 -DRON:01003012 lenacapavir Oral Tablet 2625889 -DRON:01003013 lenacapavir Injection 2625903 -DRON:01003014 adagrasib Oral Tablet 2625916 -DRON:01003015 lecanemab Injection 2626146 -DRON:01003016 ublituximab Injection 2626352 -DRON:01003017 allogeneic processed thymus tissue Drug Implant 2626463 -DRON:01003018 allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen Medicated Patch 2626474 -DRON:01003019 futibatinib Oral Tablet 2628194 -DRON:01003020 daprodustat Oral Tablet 2628214 -DRON:01003021 ascorbic acid Powder for Oral Solution 2636651 -DRON:01003022 beremagene geperpavec Topical Suspension 2637761 -DRON:01003023 sotagliflozin Oral Tablet 2638682 -DRON:01003024 rezafungin Injection 2639159 -DRON:01003025 vilobelimab Injection 2639629 -DRON:01003026 glofitamab Injection 2639785 -DRON:01003027 valoctocogene roxaparvovec Injection 2641613 -DRON:01003028 delandistrogene moxeparvovec Injection 2641678 -DRON:01003029 donislecel Injection 2642263 -DRON:01003030 rozanolixizumab Injection 2642287 -DRON:01003031 afoxolaner / moxidectin / pyrantel Chewable Tablet 2642683 -DRON:01003032 acetaminophen / chlorpheniramine Oral Solution 2645105 -DRON:01003033 omalizumab Auto-Injector 2663919 -DRON:01003034 chlorhexidine / hydrocortisone / ketoconazole Topical Spray 2663926 -DRON:01003035 albuterol / budesonide Metered Dose Inhaler 2665905 -DRON:01003036 secukinumab Injection 2667418 -DRON:01003037 dibasic potassium phosphate / potassium phosphate Injectable Solution 2667655 -DRON:01003038 bimekizumab Prefilled Syringe 2668083 -DRON:01003039 acetaminophen Granules for Oral Solution 2668205 -DRON:01003040 mirikizumab Injection 2668388 -DRON:01003041 mirikizumab Auto-Injector 2668403 -DRON:01003042 chlorhexidine / salicylic acid Topical Ointment 2668428 -DRON:01003043 entrectinib Oral Pellet 2668594 -DRON:01003044 toripalimab Injection 2669410 -DRON:01003045 fluralaner Topical Solution 2669518 -DRON:01003046 bosutinib Oral Capsule 2669662 -DRON:01003047 capivasertib Oral Tablet 2669971 -DRON:01003048 crizotinib Oral Pellet 2670165 -DRON:01003049 zinc gluconate Oral Spray 2670203 -DRON:01003050 ADAMTS13, recombinant Injection 2670289 +DRON:01002961 influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Injectable Suspension DRON:00000021 1427025 +DRON:01002962 influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe DRON:00000005 1427036 +DRON:01002963 Streptococcus pneumoniae type 1 capsular polysaccharide antigen / Streptococcus pneumoniae type 10A capsular polysaccharide antigen / Streptococcus pneumoniae type 11A capsular polysaccharide antigen / Streptococcus pneumoniae type 12F capsular polysaccharide antigen / Streptococcus pneumoniae type 14 capsular polysaccharide antigen / Streptococcus pneumoniae type 15B capsular polysaccharide antigen / Streptococcus pneumoniae type 17F capsular polysaccharide antigen / Streptococcus pneumoniae type 18C capsular polysaccharide antigen / Streptococcus pneumoniae type 19A capsular polysaccharide antigen / Streptococcus pneumoniae type 19F capsular polysaccharide antigen / Streptococcus pneumoniae type 2 capsular polysaccharide antigen / Streptococcus pneumoniae type 20 capsular polysaccharide antigen / Streptococcus pneumoniae type 22F capsular polysaccharide antigen / Streptococcus pneumoniae type 23F capsular polysaccharide antigen / Streptococcus pneumoniae type 3 capsular polysaccharide antigen / Streptococcus pneumoniae type 33F capsular polysaccharide antigen / Streptococcus pneumoniae type 4 capsular polysaccharide antigen / Streptococcus pneumoniae type 5 capsular polysaccharide antigen / Streptococcus pneumoniae type 6B capsular polysaccharide antigen / Streptococcus pneumoniae type 7F capsular polysaccharide antigen / Streptococcus pneumoniae type 8 capsular polysaccharide antigen / Streptococcus pneumoniae type 9N capsular polysaccharide antigen / Streptococcus pneumoniae type 9V capsular polysaccharide antigen Prefilled Syringe DRON:00000005 1547579 +DRON:01002964 L1 protein, human papillomavirus type 11 vaccine / L1 protein, human papillomavirus type 16 vaccine / L1 protein, human papillomavirus type 18 vaccine / L1 protein, human papillomavirus type 31 vaccine / L1 protein, human papillomavirus type 33 vaccine / L1 protein, human papillomavirus type 45 vaccine / L1 protein, human papillomavirus type 52 vaccine / L1 protein, human papillomavirus type 58 vaccine / L1 protein, human papillomavirus type 6 vaccine Prefilled Syringe DRON:00000005 1597100 +DRON:01002965 L1 protein, human papillomavirus type 11 vaccine / L1 protein, human papillomavirus type 16 vaccine / L1 protein, human papillomavirus type 18 vaccine / L1 protein, human papillomavirus type 31 vaccine / L1 protein, human papillomavirus type 33 vaccine / L1 protein, human papillomavirus type 45 vaccine / L1 protein, human papillomavirus type 52 vaccine / L1 protein, human papillomavirus type 58 vaccine / L1 protein, human papillomavirus type 6 vaccine Injection DRON:00000005 1656973 +DRON:01002966 Neisseria meningitidis serogroup A oligosaccharide diphtheria CRM197 protein conjugate vaccine / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine / Neisseria meningitidis serogroup W-135 oligosaccharide diphtheria CRM197 protein conjugate vaccine / Neisseria meningitidis serogroup Y oligosaccharide diphtheria CRM197 protein conjugate vaccine Injection DRON:00000005 1657353 +DRON:01002967 acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Injection DRON:00000005 1657394 +DRON:01002968 acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Injection DRON:00000005 1657429 +DRON:01002969 Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine / Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine Injection DRON:00000005 1657443 +DRON:01002970 Streptococcus pneumoniae type 1 capsular polysaccharide antigen / Streptococcus pneumoniae type 10A capsular polysaccharide antigen / Streptococcus pneumoniae type 11A capsular polysaccharide antigen / Streptococcus pneumoniae type 12F capsular polysaccharide antigen / Streptococcus pneumoniae type 14 capsular polysaccharide antigen / Streptococcus pneumoniae type 15B capsular polysaccharide antigen / Streptococcus pneumoniae type 17F capsular polysaccharide antigen / Streptococcus pneumoniae type 18C capsular polysaccharide antigen / Streptococcus pneumoniae type 19A capsular polysaccharide antigen / Streptococcus pneumoniae type 19F capsular polysaccharide antigen / Streptococcus pneumoniae type 2 capsular polysaccharide antigen / Streptococcus pneumoniae type 20 capsular polysaccharide antigen / Streptococcus pneumoniae type 22F capsular polysaccharide antigen / Streptococcus pneumoniae type 23F capsular polysaccharide antigen / Streptococcus pneumoniae type 3 capsular polysaccharide antigen / Streptococcus pneumoniae type 33F capsular polysaccharide antigen / Streptococcus pneumoniae type 4 capsular polysaccharide antigen / Streptococcus pneumoniae type 5 capsular polysaccharide antigen / Streptococcus pneumoniae type 6B capsular polysaccharide antigen / Streptococcus pneumoniae type 7F capsular polysaccharide antigen / Streptococcus pneumoniae type 8 capsular polysaccharide antigen / Streptococcus pneumoniae type 9N capsular polysaccharide antigen / Streptococcus pneumoniae type 9V capsular polysaccharide antigen Injection DRON:00000005 1658469 +DRON:01002971 aspirin / calcium carbonate Oral Tablet DRON:00000022 1722688 +DRON:01002972 botulinum neurotoxin A immune FAB2 / botulinum neurotoxin B immune FAB2 / botulinum neurotoxin C immune FAB2 / botulinum neurotoxin D immune FAB2 / botulinum neurotoxin E immune FAB2 / botulinum neurotoxin F immune FAB2 / botulinum neurotoxin G immune FAB2 Injection DRON:00000005 1722717 +DRON:01002973 heparin Injectable Solution DRON:00000020 1856275 +DRON:01002974 heparin Prefilled Syringe DRON:00000005 1856278 +DRON:01002975 glutamine Powder for Oral Solution DRON:00000005 1869683 +DRON:01002976 ropivacaine Prefilled Syringe DRON:00000005 1996290 +DRON:01002977 gemcitabine Injectable Solution DRON:00000020 1998782 +DRON:01002978 cefepime Injectable Solution DRON:00000020 2058952 +DRON:01002979 acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine / hepatitis B surface antigen vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Injection DRON:00000005 2109613 +DRON:01002980 thyrotropin alfa Injection DRON:00000005 2166571 +DRON:01002981 acetaminophen / chlorpheniramine / phenylephrine Oral Solution DRON:00000020 2178940 +DRON:01002982 glucagon Prefilled Syringe DRON:00000005 2199309 +DRON:01002983 zinc sulfate Injectable Solution DRON:00000020 2201520 +DRON:01002984 ethanol / iodine / sodium iodide Topical Solution DRON:00000020 2265290 +DRON:01002985 Atlantic halibut allergenic extract Injectable Solution DRON:00000020 2274704 +DRON:01002986 amphotericin B Injectable Solution DRON:00000020 2285811 +DRON:01002987 Neisseria meningitidis serogroup A capsular polysaccharide tetanus toxoid protein conjugate vaccine / Neisseria meningitidis serogroup C capsular polysaccharide tetanus toxoid protein conjugate vaccine / Neisseria meningitidis serogroup W-135 capsular polysaccharide tetanus toxoid protein conjugate vaccine / Neisseria meningitidis serogroup Y capsular polysaccharide tetanus toxoid protein conjugate vaccine Injection DRON:00000005 2360581 +DRON:01002988 acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine / hepatitis B surface antigen vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Prefilled Syringe DRON:00000005 2468236 +DRON:01002989 oxymetazoline Nasal Gel DRON:00000015 2474263 +DRON:01002990 fentanyl Prefilled Syringe DRON:00000005 2474266 +DRON:01002991 Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 10A capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 11A capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 12F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 15B capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 22F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 33F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 8 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine Prefilled Syringe DRON:00000005 2566307 +DRON:01002992 Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 22F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 33F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine Prefilled Syringe DRON:00000005 2566415 +DRON:01002993 dextromethorphan / doxylamine / phenylephrine Oral Solution DRON:00000020 2566813 +DRON:01002994 glycerin Topical Gel DRON:00000015 2586848 +DRON:01002995 pemetrexed Injectable Solution DRON:00000020 2590671 +DRON:01002996 succinylcholine Prefilled Syringe DRON:00000005 2598127 +DRON:01002997 labetalol Prefilled Syringe DRON:00000005 2598342 +DRON:01002998 dotatate Injection DRON:00000005 2599510 +DRON:01002999 doramectin / levamisole Injectable Solution DRON:00000020 2611785 +DRON:01003000 abametapir Topical Lotion DRON:00000018 2618847 +DRON:01003001 risdiplam Oral Solution DRON:00000020 2618856 +DRON:01003002 Bifidobacterium infantis Chewable Tablet DRON:00000022 2618885 +DRON:01003003 Bifidobacterium infantis Oral Capsule DRON:00000026 2618892 +DRON:01003004 Bifidobacterium infantis Powder for Oral Suspension DRON:00000005 2618901 +DRON:01003005 clascoterone Topical Cream DRON:00000017 2618910 +DRON:01003006 casimersen Injection DRON:00000005 2618918 +DRON:01003007 rimegepant Disintegrating Oral Tablet DRON:00000022 2618951 +DRON:01003008 oliceridine Injection DRON:00000005 2618959 +DRON:01003009 Bifidobacterium infantis Oral Powder DRON:00000005 2619040 +DRON:01003010 teprotumumab Injection DRON:00000005 2619146 +DRON:01003011 omeprazole / sodium bicarbonate Oral Suspension DRON:00000021 2625143 +DRON:01003012 lenacapavir Oral Tablet DRON:00000022 2625889 +DRON:01003013 lenacapavir Injection DRON:00000005 2625903 +DRON:01003014 adagrasib Oral Tablet DRON:00000022 2625916 +DRON:01003015 lecanemab Injection DRON:00000005 2626146 +DRON:01003016 ublituximab Injection DRON:00000005 2626352 +DRON:01003017 allogeneic processed thymus tissue Drug Implant DRON:00000005 2626463 +DRON:01003018 allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen Medicated Patch DRON:00000005 2626474 +DRON:01003019 futibatinib Oral Tablet DRON:00000022 2628194 +DRON:01003020 daprodustat Oral Tablet DRON:00000022 2628214 +DRON:01003021 ascorbic acid Powder for Oral Solution DRON:00000005 2636651 +DRON:01003022 beremagene geperpavec Topical Suspension DRON:00000005 2637761 +DRON:01003023 sotagliflozin Oral Tablet DRON:00000022 2638682 +DRON:01003024 rezafungin Injection DRON:00000005 2639159 +DRON:01003025 vilobelimab Injection DRON:00000005 2639629 +DRON:01003026 glofitamab Injection DRON:00000005 2639785 +DRON:01003027 valoctocogene roxaparvovec Injection DRON:00000005 2641613 +DRON:01003028 delandistrogene moxeparvovec Injection DRON:00000005 2641678 +DRON:01003029 donislecel Injection DRON:00000005 2642263 +DRON:01003030 rozanolixizumab Injection DRON:00000005 2642287 +DRON:01003031 afoxolaner / moxidectin / pyrantel Chewable Tablet DRON:00000022 2642683 +DRON:01003032 acetaminophen / chlorpheniramine Oral Solution DRON:00000020 2645105 +DRON:01003033 omalizumab Auto-Injector DRON:00000005 2663919 +DRON:01003034 chlorhexidine / hydrocortisone / ketoconazole Topical Spray DRON:00000005 2663926 +DRON:01003035 albuterol / budesonide Metered Dose Inhaler DRON:00000005 2665905 +DRON:01003036 secukinumab Injection DRON:00000005 2667418 +DRON:01003037 dibasic potassium phosphate / potassium phosphate Injectable Solution DRON:00000020 2667655 +DRON:01003038 bimekizumab Prefilled Syringe DRON:00000005 2668083 +DRON:01003039 acetaminophen Granules for Oral Solution DRON:00000005 2668205 +DRON:01003040 mirikizumab Injection DRON:00000005 2668388 +DRON:01003041 mirikizumab Auto-Injector DRON:00000005 2668403 +DRON:01003042 chlorhexidine / salicylic acid Topical Ointment DRON:00000019 2668428 +DRON:01003043 entrectinib Oral Pellet DRON:00000005 2668594 +DRON:01003044 toripalimab Injection DRON:00000005 2669410 +DRON:01003045 fluralaner Topical Solution DRON:00000020 2669518 +DRON:01003046 bosutinib Oral Capsule DRON:00000026 2669662 +DRON:01003047 capivasertib Oral Tablet DRON:00000022 2669971 +DRON:01003048 crizotinib Oral Pellet DRON:00000005 2670165 +DRON:01003049 zinc gluconate Oral Spray DRON:00000005 2670203 +DRON:01003050 ADAMTS13, recombinant Injection DRON:00000005 2670289 diff --git a/src/templates/dose_form.tsv b/src/templates/dose_form.tsv new file mode 100644 index 0000000..be7daf9 --- /dev/null +++ b/src/templates/dose_form.tsv @@ -0,0 +1,76 @@ +rxcui label curie +7670 Ophthalmic Solution DRON:00000020 +152903 Irrigation Solution DRON:00000020 +244286 Ophthalmic Irrigation Solution DRON:00000020 +316949 Injectable Solution DRON:00000020 +316951 Intraperitoneal Solution DRON:00000020 +316952 Intravenous Solution DRON:00000020 +316956 Mucous Membrane Topical Solution DRON:00000020 +316962 Nasal Solution DRON:00000020 +316968 Oral Solution DRON:00000020 +316973 Otic Solution DRON:00000020 +316986 Topical Solution DRON:00000020 +317006 Rectal Solution DRON:00000020 +346161 Inhalation Solution DRON:00000020 +346166 Intramuscular Solution DRON:00000020 +450530 Solution DRON:00000020 +196572 Elixir DRON:00000020 +316981 Syrup DRON:00000020 +10311 Tablet DRON:00000022 +11110 Vaginal Tablet DRON:00000022 +91058 Chewable Tablet DRON:00000022 +316945 Extended Release Oral Tablet DRON:00000022 +316936 24 Hour Extended Release Tablet DRON:00000022 +316942 Disintegrating Tablet DRON:00000022 +316980 Sustained Release Buccal Tablet DRON:00000022 +317007 Sublingual Tablet DRON:00000022 +317541 Oral Tablet DRON:00000022 +970789 Buccal Tablet DRON:00000022 +10269 Suspension DRON:00000021 +316946 Extended Release Suspension DRON:00000021 +316950 Injectable Suspension DRON:00000021 +316969 Oral Suspension DRON:00000021 +316974 Otic Suspension DRON:00000021 +316979 Rectal Suspension DRON:00000021 +317001 Intrathecal Suspension DRON:00000021 +346167 Intramuscular Suspension DRON:00000021 +346168 Intravenous Suspension DRON:00000021 +346290 Nasal Suspension DRON:00000021 +7628 Ointment DRON:00000019 +91344 Opthalmic Ointment DRON:00000019 +316961 Nasal Ointment DRON:00000019 +316972 Otic Ointment DRON:00000019 +316985 Topical Ointment DRON:00000019 +317005 Rectal Ointment DRON:00000019 +317010 Vaginal Ointment DRON:00000019 +346288 Oral Ointment DRON:00000019 +848125 Augmented Topical Ointment DRON:00000019 +4718 Gel DRON:00000015 +11108 Vaginal Gel DRON:00000015 +316960 Nasal Gel DRON:00000015 +316963 Ophthalmic Gel DRON:00000015 +346169 Oral Gel DRON:00000015 +346170 Rectal Gel DRON:00000015 +346286 Topical Gel DRON:00000015 +346287 Urethral Gel DRON:00000015 +848198 Augmented Topical Gel DRON:00000015 +11103 Vaginal Cream DRON:00000017 +316957 Nasal Cream DRON:00000017 +316966 Oral Cream DRON:00000017 +316971 Otic Cream DRON:00000017 +316975 Rectal Cream DRON:00000017 +316982 Topical Cream DRON:00000017 +317544 Ophthalmic Cream DRON:00000017 +446669 Cream DRON:00000017 +848123 Augmented Topical Cream DRON:00000017 +1995 Capsule DRON:00000026 +316943 Extended Release Oral Capsule DRON:00000026 +316965 Oral Capsule DRON:00000026 +316997 24 Hour Extended Release Capsule DRON:00000026 +11107 Vaginal Foam DRON:00000024 +316948 Foam DRON:00000024 +346284 Oral Foam DRON:00000024 +346285 Topical Foam DRON:00000024 +142222 Lotion DRON:00000018 +316983 Topical Lotion DRON:00000018 +848124 Augmented Topical Lotion DRON:00000018