diff --git a/src/Microsoft.ComponentDetection.Orchestrator/Experiments/Configs/IExperimentConfiguration.cs b/src/Microsoft.ComponentDetection.Orchestrator/Experiments/Configs/IExperimentConfiguration.cs
index 49a4b3f48..cbfdf8851 100644
--- a/src/Microsoft.ComponentDetection.Orchestrator/Experiments/Configs/IExperimentConfiguration.cs
+++ b/src/Microsoft.ComponentDetection.Orchestrator/Experiments/Configs/IExperimentConfiguration.cs
@@ -1,5 +1,6 @@
 namespace Microsoft.ComponentDetection.Orchestrator.Experiments.Configs;
 
+using System.Threading.Tasks;
 using Microsoft.ComponentDetection.Contracts;
 
 /// <summary>
@@ -15,6 +16,12 @@ public interface IExperimentConfiguration
     /// </summary>
     string Name { get; }
 
+    /// <summary>
+    /// Initializes the experiment configuration.
+    /// </summary>
+    /// <returns>A <see cref="Task"/> representing the asynchronous operation.</returns>
+    Task InitAsync() => Task.CompletedTask;
+
     /// <summary>
     /// Specifies if the detector is in the control group.
     /// </summary>
diff --git a/src/Microsoft.ComponentDetection.Orchestrator/Experiments/Configs/RustCliDetectorExperiment.cs b/src/Microsoft.ComponentDetection.Orchestrator/Experiments/Configs/RustCliDetectorExperiment.cs
index e17e71696..3ec089917 100644
--- a/src/Microsoft.ComponentDetection.Orchestrator/Experiments/Configs/RustCliDetectorExperiment.cs
+++ b/src/Microsoft.ComponentDetection.Orchestrator/Experiments/Configs/RustCliDetectorExperiment.cs
@@ -1,5 +1,6 @@
 namespace Microsoft.ComponentDetection.Orchestrator.Experiments.Configs;
 
+using System.Threading.Tasks;
 using Microsoft.ComponentDetection.Contracts;
 using Microsoft.ComponentDetection.Detectors.Rust;
 
@@ -8,6 +9,15 @@ namespace Microsoft.ComponentDetection.Orchestrator.Experiments.Configs;
 /// </summary>
 public class RustCliDetectorExperiment : IExperimentConfiguration
 {
+    private readonly ICommandLineInvocationService commandLineInvocationService;
+    private bool cargoCliAvailable;
+
+    /// <summary>
+    /// Initializes a new instance of the <see cref="RustCliDetectorExperiment"/> class.
+    /// </summary>
+    /// <param name="commandLineInvocationService">The command line invocation service.</param>
+    public RustCliDetectorExperiment(ICommandLineInvocationService commandLineInvocationService) => this.commandLineInvocationService = commandLineInvocationService;
+
     /// <inheritdoc />
     public string Name => "RustCliDetector";
 
@@ -18,5 +28,8 @@ public class RustCliDetectorExperiment : IExperimentConfiguration
     public bool IsInExperimentGroup(IComponentDetector componentDetector) => componentDetector is RustCliDetector;
 
     /// <inheritdoc />
-    public bool ShouldRecord(IComponentDetector componentDetector, int numComponents) => true;
+    public bool ShouldRecord(IComponentDetector componentDetector, int numComponents) => this.cargoCliAvailable;
+
+    /// <inheritdoc />
+    public async Task InitAsync() => this.cargoCliAvailable = await this.commandLineInvocationService.CanCommandBeLocatedAsync("cargo", null);
 }
diff --git a/src/Microsoft.ComponentDetection.Orchestrator/Experiments/ExperimentService.cs b/src/Microsoft.ComponentDetection.Orchestrator/Experiments/ExperimentService.cs
index 68939cd28..30bcc5c44 100644
--- a/src/Microsoft.ComponentDetection.Orchestrator/Experiments/ExperimentService.cs
+++ b/src/Microsoft.ComponentDetection.Orchestrator/Experiments/ExperimentService.cs
@@ -43,6 +43,23 @@ public ExperimentService(
         this.logger = logger;
     }
 
+    /// <inheritdoc />
+    public async Task InitializeAsync()
+    {
+        foreach (var config in this.experiments.Keys)
+        {
+            try
+            {
+                await config.InitAsync();
+            }
+            catch (Exception e)
+            {
+                this.logger.LogWarning(e, "Failed to initialize experiment {Experiment}, skipping it", config.Name);
+                this.experiments.TryRemove(config, out _);
+            }
+        }
+    }
+
     /// <inheritdoc />
     public void RecordDetectorRun(
         IComponentDetector detector,
diff --git a/src/Microsoft.ComponentDetection.Orchestrator/Experiments/IExperimentService.cs b/src/Microsoft.ComponentDetection.Orchestrator/Experiments/IExperimentService.cs
index 4477abbbc..9e00a2c9c 100644
--- a/src/Microsoft.ComponentDetection.Orchestrator/Experiments/IExperimentService.cs
+++ b/src/Microsoft.ComponentDetection.Orchestrator/Experiments/IExperimentService.cs
@@ -11,6 +11,12 @@ namespace Microsoft.ComponentDetection.Orchestrator.Experiments;
 /// </summary>
 public interface IExperimentService
 {
+    /// <summary>
+    /// Initializes the experiment services by preparing the experiment configurations.
+    /// </summary>
+    /// <returns>A <see cref="Task"/> representing the asynchronous operation.</returns>
+    Task InitializeAsync();
+
     /// <summary>
     /// Records the results of a detector execution and processes the results for any active experiments.
     /// </summary>
diff --git a/src/Microsoft.ComponentDetection.Orchestrator/Services/DetectorProcessingService.cs b/src/Microsoft.ComponentDetection.Orchestrator/Services/DetectorProcessingService.cs
index 658de9a71..93e17ea44 100644
--- a/src/Microsoft.ComponentDetection.Orchestrator/Services/DetectorProcessingService.cs
+++ b/src/Microsoft.ComponentDetection.Orchestrator/Services/DetectorProcessingService.cs
@@ -55,6 +55,7 @@ public async Task<DetectorProcessingResult> ProcessDetectorsAsync(
             ? this.GenerateDirectoryExclusionPredicate(settings.SourceDirectory.ToString(), settings.DirectoryExclusionList, settings.DirectoryExclusionListObsolete, allowWindowsPaths: false, ignoreCase: false)
             : this.GenerateDirectoryExclusionPredicate(settings.SourceDirectory.ToString(), settings.DirectoryExclusionList, settings.DirectoryExclusionListObsolete, allowWindowsPaths: true, ignoreCase: true);
 
+        await this.experimentService.InitializeAsync();
         this.experimentService.RemoveUnwantedExperimentsbyDetectors(detectorRestrictions.DisabledDetectors);
 
         IEnumerable<Task<(IndividualDetectorScanResult, ComponentRecorder, IComponentDetector)>> scanTasks = detectors
diff --git a/test/Microsoft.ComponentDetection.Orchestrator.Tests/Experiments/ExperimentServiceTests.cs b/test/Microsoft.ComponentDetection.Orchestrator.Tests/Experiments/ExperimentServiceTests.cs
index 3c5df555c..c867f8ddb 100644
--- a/test/Microsoft.ComponentDetection.Orchestrator.Tests/Experiments/ExperimentServiceTests.cs
+++ b/test/Microsoft.ComponentDetection.Orchestrator.Tests/Experiments/ExperimentServiceTests.cs
@@ -1,5 +1,6 @@
 namespace Microsoft.ComponentDetection.Orchestrator.Tests.Experiments;
 
+using System;
 using System.Collections.Generic;
 using System.IO;
 using System.Linq;
@@ -279,9 +280,9 @@ public async Task RecordDetectorRun_CheckUnwantedDetectors_RemoveExperimentAsync
         var detectorList = new List<IComponentDetector>
         {
             new NuGetComponentDetector(
-            new Mock<IComponentStreamEnumerableFactory>().Object,
-            new Mock<IObservableDirectoryWalkerFactory>().Object,
-            new Mock<ILogger<NuGetComponentDetector>>().Object), this.detectorMock.Object,
+                new Mock<IComponentStreamEnumerableFactory>().Object,
+                new Mock<IObservableDirectoryWalkerFactory>().Object,
+                new Mock<ILogger<NuGetComponentDetector>>().Object), this.detectorMock.Object,
         };
 
         service.RemoveUnwantedExperimentsbyDetectors(detectorList);
@@ -310,9 +311,9 @@ public async Task RecordDetectorRun_CheckUnwantedDetectors_KeepExperimentAsync()
         var detectorList = new List<IComponentDetector>
         {
             new NuGetComponentDetector(
-            new Mock<IComponentStreamEnumerableFactory>().Object,
-            new Mock<IObservableDirectoryWalkerFactory>().Object,
-            new Mock<ILogger<NuGetComponentDetector>>().Object),
+                new Mock<IComponentStreamEnumerableFactory>().Object,
+                new Mock<IObservableDirectoryWalkerFactory>().Object,
+                new Mock<ILogger<NuGetComponentDetector>>().Object),
         };
 
         service.RemoveUnwantedExperimentsbyDetectors(detectorList);
@@ -325,4 +326,35 @@ public async Task RecordDetectorRun_CheckUnwantedDetectors_KeepExperimentAsync()
             x => x.ProcessExperimentAsync(this.experimentConfigMock.Object, It.IsAny<ExperimentDiff>()),
             Times.Once());
     }
+
+    [TestMethod]
+    public async Task InitializeAsync_InitsConfigsAsync()
+    {
+        var service = new ExperimentService(
+            new[] { this.experimentConfigMock.Object },
+            new[] { this.experimentProcessorMock.Object },
+            this.graphTranslationServiceMock.Object,
+            this.loggerMock.Object);
+
+        await service.InitializeAsync();
+
+        this.experimentConfigMock.Verify(x => x.InitAsync(), Times.Once());
+    }
+
+    [TestMethod]
+    public async Task InitializeAsync_SwallowsExceptionsAsync()
+    {
+        this.experimentConfigMock.Setup(x => x.InitAsync()).ThrowsAsync(new InvalidOperationException());
+
+        var service = new ExperimentService(
+            new[] { this.experimentConfigMock.Object },
+            new[] { this.experimentProcessorMock.Object },
+            this.graphTranslationServiceMock.Object,
+            this.loggerMock.Object);
+
+        var action = async () => await service.InitializeAsync();
+
+        await action.Should().NotThrowAsync();
+        this.experimentConfigMock.Verify(x => x.InitAsync(), Times.Once());
+    }
 }
diff --git a/test/Microsoft.ComponentDetection.Orchestrator.Tests/Services/DetectorProcessingServiceTests.cs b/test/Microsoft.ComponentDetection.Orchestrator.Tests/Services/DetectorProcessingServiceTests.cs
index 936384915..417570e8c 100644
--- a/test/Microsoft.ComponentDetection.Orchestrator.Tests/Services/DetectorProcessingServiceTests.cs
+++ b/test/Microsoft.ComponentDetection.Orchestrator.Tests/Services/DetectorProcessingServiceTests.cs
@@ -321,17 +321,17 @@ public async Task ProcessDetectorsAsync_DirectoryExclusionPredicateWorksAsExpect
     public void GenerateDirectoryExclusionPredicate_IgnoreCaseAndAllowWindowsPathsWorksAsExpected()
     {
         /*
-        * We can't test a scenario like:
-        *
-        * SourceDirectory = /Some/Source/Directory
-        * DirectoryExclusionList = *Some/*
-        * allowWindowsPath = false
-        *
-        * and expect to exclude the directory, because when
-        * we pass the SourceDirectory path to DirectoryInfo and we are running the test on Windows,
-        * DirectoryInfo transalate it to C:\\Some\Source\Directory
-        * making the test fail
-        */
+         * We can't test a scenario like:
+         *
+         * SourceDirectory = /Some/Source/Directory
+         * DirectoryExclusionList = *Some/*
+         * allowWindowsPath = false
+         *
+         * and expect to exclude the directory, because when
+         * we pass the SourceDirectory path to DirectoryInfo and we are running the test on Windows,
+         * DirectoryInfo transalate it to C:\\Some\Source\Directory
+         * making the test fail
+         */
 
         if (!RuntimeInformation.IsOSPlatform(OSPlatform.Windows))
         {
@@ -534,6 +534,19 @@ public async Task ProcessDetectorsAsync_RecordsDetectorRunsAsync()
             Times.Once());
     }
 
+    [TestMethod]
+    public async Task ProcessDetectorsAsync_InitializesExperimentsAsync()
+    {
+        this.detectorsToUse = new[]
+        {
+            this.firstFileComponentDetectorMock.Object, this.secondFileComponentDetectorMock.Object,
+        };
+
+        await this.serviceUnderTest.ProcessDetectorsAsync(DefaultArgs, this.detectorsToUse, new DetectorRestrictions());
+
+        this.experimentServiceMock.Verify(x => x.InitializeAsync(), Times.Once);
+    }
+
     private Mock<FileComponentDetector> SetupFileDetectorMock(string id)
     {
         var mockFileDetector = new Mock<FileComponentDetector>();