diff --git a/testsuite/pytests/sli2py_regressions/test_ticket_459.py b/testsuite/pytests/sli2py_regressions/test_ticket_459.py
new file mode 100644
index 0000000000..103a0497e3
--- /dev/null
+++ b/testsuite/pytests/sli2py_regressions/test_ticket_459.py
@@ -0,0 +1,58 @@
+# -*- coding: utf-8 -*-
+#
+# test_ticket_459.py
+#
+# This file is part of NEST.
+#
+# Copyright (C) 2004 The NEST Initiative
+#
+# NEST is free software: you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation, either version 2 of the License, or
+# (at your option) any later version.
+#
+# NEST is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+# GNU General Public License for more details.
+#
+# You should have received a copy of the GNU General Public License
+# along with NEST.  If not, see <http://www.gnu.org/licenses/>.
+
+"""
+Test that changing E_L in any neuron with this parameter leaves all other parameters unchanged.
+"""
+
+import pytest
+
+import nest
+
+
+@pytest.fixture(autouse=True)
+def reset():
+    nest.ResetKernel()
+
+
+# Collect all models with E_L parameter.
+# Skip gif_cond_exp_multisynapse because it has numpy array parameter making check below difficult.
+models_with_EL = [model for model in nest.node_models if "E_L" in nest.GetDefaults(model)]
+models_with_EL.remove("gif_cond_exp_multisynapse")
+
+
+@pytest.mark.parametrize("model", models_with_EL)
+def test_clean_EL_change(model):
+    nrn = nest.Create(model)
+    orig_params = nest.GetStatus(nrn)[0]
+
+    EL_orig = orig_params["E_L"]
+    EL_new = EL_orig + 0.7
+    nrn.E_L = EL_new
+
+    # Confirm E_L has been changed.
+    assert nrn.get("E_L") == EL_new
+
+    # Confirm all other parameters are equal to original values.
+    new_params = nest.GetStatus(nrn)[0]
+    del orig_params["E_L"]
+    del new_params["E_L"]
+    assert new_params == orig_params
diff --git a/testsuite/pytests/sli2py_regressions/ticket_754.py b/testsuite/pytests/sli2py_regressions/test_ticket_754.py
similarity index 99%
rename from testsuite/pytests/sli2py_regressions/ticket_754.py
rename to testsuite/pytests/sli2py_regressions/test_ticket_754.py
index 9f2ec3ff40..f92a1fb0a8 100644
--- a/testsuite/pytests/sli2py_regressions/ticket_754.py
+++ b/testsuite/pytests/sli2py_regressions/test_ticket_754.py
@@ -1,6 +1,6 @@
 # -*- coding: utf-8 -*-
 #
-# ticket_754.py
+# test_ticket_754.py
 #
 # This file is part of NEST.
 #
diff --git a/testsuite/regressiontests/ticket-459.sli b/testsuite/regressiontests/ticket-459.sli
deleted file mode 100644
index 4ecf543c1a..0000000000
--- a/testsuite/regressiontests/ticket-459.sli
+++ /dev/null
@@ -1,104 +0,0 @@
-/*
- *  ticket-459.sli
- *
- *  This file is part of NEST.
- *
- *  Copyright (C) 2004 The NEST Initiative
- *
- *  NEST is free software: you can redistribute it and/or modify
- *  it under the terms of the GNU General Public License as published by
- *  the Free Software Foundation, either version 2 of the License, or
- *  (at your option) any later version.
- *
- *  NEST is distributed in the hope that it will be useful,
- *  but WITHOUT ANY WARRANTY; without even the implied warranty of
- *  MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
- *  GNU General Public License for more details.
- *
- *  You should have received a copy of the GNU General Public License
- *  along with NEST.  If not, see <http://www.gnu.org/licenses/>.
- *
- */
-
-
-/** @BeginDocumentation
-Name: testsuite::ticket-459 - test that changing the leak reversal potential leaves all other neuron parameters else unchanged
-
-Synopsis: (ticket-459.sli) run -> dies if assertion fails
-
-Description:
-For all models having a reversal potential E_L, we change this potential and check that
-all other parameters and properties of the model remain unchanged. #459 reports that the
-order in which E_L and V_th are set determines which values are actually set. This is a
-direct consequence of incorrect handling of changes to E_L, which show up as changes in,
-e.g. V_m and V_th as a side effect of changing E_L. This happened in those neuron models
-that internally represent voltages relative to E_L and did not adjust those values on
-changes to E_L.
-
-Author: Plesser
-FirstVersion: 2011-02-12
-*/
-
-(unittest) run
-/unittest using
-
-M_ERROR setverbosity
-
-% Execute test for one model
-% Argument: model name
-% Result: true or false
-/run_test
-{
-  /model Set
-  model Create /nrn Set
-
-  % find any keys to double values that are not finite
-  % set them to finite value to make sure that they will
-  % be tested below
-  /infdict << >> def
-  model GetDefaults /mdefs Set
-  mdefs keys
-  {  /k Set mdefs k get DoubleQ { FiniteQ not { infdict k -150. put } if } if pop }
-  forall
-  nrn infdict SetStatus
-
-  nrn GetStatus 0 get /pre Set
-  pre /E_L get /ELorig Set
-
-  ELorig 1.0 add /ELnew Set
-  nrn << /E_L ELnew >> SetStatus
-  nrn GetStatus 0 get /post Set
-
-  pre keys post keys eq assert
-  % compare all numeric pre-post values, except changed E_L
-  pre /E_L undef pre keys
-  {
-    /key Set
-     pre key get DoubleQ
-     {
-        dup post key get sub abs % |post-pre| < 1e-15 |pre|
-        exch abs 1e-15 mul leq
-     }
-     { pop true }
-     ifelse
-  } Map
-  true exch { and } Fold
-  dup not { model =only (  FAILED) = } if
-}
-def
-
-{
-  GetKernelStatus /node_models get
-  {
-    dup GetDefaults /E_L known
-    {
-      run_test
-    }
-    {
-      pop   % no E_L, pass, true by default
-      true
-    } ifelse
-  } Map
-  true exch { and } Fold
-}
-assert_or_die