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Import and analyse large-scale biomedical knowledge graphs and ontologies. 🕸️⚙️💻⚙️🕸️

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KGExplorer


License: GPL-3
R build status

Authors: Brian Schilder

README updated: Mar-08-2024

KGExplorer: Biomedical Knowledge Network Construction and Analysis

Query, construct, and analyse large-scale biomedical knowledge graphs and ontologies.

If you use KGExplorer, please cite:

Kitty B. Murphy, Robert Gordon-Smith, Jai Chapman, Momoko Otani, Brian M. Schilder, Nathan G. Skene (2023) Identification of cell type-specific gene targets underlying thousands of rare diseases and subtraits. medRxiv, https://doi.org/10.1101/2023.02.13.23285820

Installation

if(!require("BiocManager")) install.packages("BiocManager")

BiocManager::install("neurogenomics/KGExplorer")
library(KGExplorer)

Documentation


Session Info

utils::sessionInfo()
## R version 4.3.1 (2023-06-16)
## Platform: aarch64-apple-darwin20 (64-bit)
## Running under: macOS Sonoma 14.3.1
## 
## Matrix products: default
## BLAS:   /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/lib/libRblas.0.dylib 
## LAPACK: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/lib/libRlapack.dylib;  LAPACK version 3.11.0
## 
## locale:
## [1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8
## 
## time zone: Europe/London
## tzcode source: internal
## 
## attached base packages:
## [1] stats     graphics  grDevices utils     datasets  methods   base     
## 
## loaded via a namespace (and not attached):
##  [1] gtable_0.3.4        jsonlite_1.8.8      renv_1.0.3         
##  [4] dplyr_1.1.4         compiler_4.3.1      BiocManager_1.30.22
##  [7] tidyselect_1.2.0    rvcheck_0.2.1       scales_1.3.0       
## [10] yaml_2.3.8          fastmap_1.1.1       here_1.0.1         
## [13] ggplot2_3.4.4       R6_2.5.1            generics_0.1.3     
## [16] knitr_1.45          yulab.utils_0.1.4   tibble_3.2.1       
## [19] desc_1.4.3          dlstats_0.1.7       rprojroot_2.0.4    
## [22] munsell_0.5.0       pillar_1.9.0        RColorBrewer_1.1-3 
## [25] rlang_1.1.3         utf8_1.2.4          cachem_1.0.8       
## [28] badger_0.2.3        xfun_0.42           fs_1.6.3           
## [31] memoise_2.0.1.9000  cli_3.6.2           magrittr_2.0.3     
## [34] rworkflows_1.0.1    digest_0.6.34       grid_4.3.1         
## [37] rstudioapi_0.15.0   lifecycle_1.0.4     vctrs_0.6.5        
## [40] data.table_1.15.0   evaluate_0.23       glue_1.7.0         
## [43] fansi_1.0.6         colorspace_2.1-0    rmarkdown_2.25     
## [46] tools_4.3.1         pkgconfig_2.0.3     htmltools_0.5.7

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Import and analyse large-scale biomedical knowledge graphs and ontologies. 🕸️⚙️💻⚙️🕸️

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