From 101f5fe77d7a695e8b5e72af61329b32dddb66ff Mon Sep 17 00:00:00 2001
From: John Huddleston <huddlej@gmail.com>
Date: Fri, 30 Aug 2024 14:22:41 -0700
Subject: [PATCH] Add segment-specific Auspice configs for 2y builds

Adds segment-specific Auspice config JSONs for 2y builds of H1N1pdm,
H3N2, and Vic with custom color scales for subclades within each subtype
and segment. These color scales match the scales used in the
nextflu-private builds, allowing us to include the public trees in our
monthly reports and easily switch between private and public trees
without changing color schemes across builds.

With this change, we can remove the "representative" builds from the
nextflu-private build config, since the public builds already provide
equal geographic and temporal sampling.

Closes #164
---
 config/h1n1pdm/ha/auspice_config.json | 243 ++++++++++++++++++++++++++
 config/h1n1pdm/na/auspice_config.json | 208 ++++++++++++++++++++++
 config/h3n2/ha/auspice_config.json    | 221 +++++++++++++++++++++++
 config/h3n2/na/auspice_config.json    | 193 ++++++++++++++++++++
 config/vic/ha/auspice_config.json     | 200 +++++++++++++++++++++
 config/vic/na/auspice_config.json     | 193 ++++++++++++++++++++
 profiles/nextflu-private.yaml         |  92 +---------
 profiles/nextstrain-public.yaml       |  21 ++-
 8 files changed, 1278 insertions(+), 93 deletions(-)
 create mode 100644 config/h1n1pdm/ha/auspice_config.json
 create mode 100644 config/h1n1pdm/na/auspice_config.json
 create mode 100644 config/h3n2/ha/auspice_config.json
 create mode 100644 config/h3n2/na/auspice_config.json
 create mode 100644 config/vic/ha/auspice_config.json
 create mode 100644 config/vic/na/auspice_config.json

diff --git a/config/h1n1pdm/ha/auspice_config.json b/config/h1n1pdm/ha/auspice_config.json
new file mode 100644
index 00000000..40239891
--- /dev/null
+++ b/config/h1n1pdm/ha/auspice_config.json
@@ -0,0 +1,243 @@
+{
+  "title": "Real-time tracking of influenza A/H1N1pdm evolution",
+  "maintainers": [
+    {
+      "name": "Jennifer Chang",
+      "url": "https://bedford.io/team/jennifer-chang/"
+    },
+    {
+      "name": "Jover Lee",
+      "url": "https://bedford.io/team/jover-lee/"
+    },
+    {
+      "name": "John Huddleston",
+      "url": "https://bedford.io/team/john-huddleston/"
+    },
+    {
+      "name": "Richard Neher",
+      "url": "https://neherlab.org/richard-neher.html"
+    },
+    {
+      "name": "Trevor Bedford",
+      "url": "https://bedford.io/team/trevor-bedford/"
+    }
+  ],
+  "data_provenance": [
+    {
+      "name": "GISAID"
+    }
+  ],
+  "build_url": "https://github.com/nextstrain/seasonal-flu",
+  "colorings": [
+    {
+      "key": "gt",
+      "title": "Genotype",
+      "type": "categorical"
+    },
+    {
+      "key": "num_date",
+      "title": "Date",
+      "type": "continuous"
+    },
+    {
+      "key": "clade_membership",
+      "title": "Clade",
+      "type": "categorical"
+    },
+    {
+      "key": "subclade",
+      "title": "Subclade",
+      "type": "categorical",
+      "scale": [
+        [
+          "C.1",
+          "#492AB5"
+        ],
+        [
+          "C.1.1",
+          "#3F4CCB"
+        ],
+        [
+          "C.1.2",
+          "#4271CE"
+        ],
+        [
+          "C.1.5",
+          "#4C8FC0"
+        ],
+        [
+          "C.1.7",
+          "#5AA5A8"
+        ],
+        [
+          "C.1.7.1",
+          "#6DB38A"
+        ],
+        [
+          "C.1.7.2",
+          "#85BA6F"
+        ],
+        [
+          "C.1.8",
+          "#A0BE59"
+        ],
+        [
+          "C.1.9",
+          "#BBBC49"
+        ],
+        [
+          "D",
+          "#D2B340"
+        ],
+        [
+          "D.1",
+          "#E19F3A"
+        ],
+        [
+          "D.2",
+          "#E68033"
+        ],
+        [
+          "D.3",
+          "#E2562B"
+        ],
+        [
+          "D.4",
+          "#DB2823"
+        ]
+      ]
+    },
+    {
+      "key": "haplotype",
+      "title": "Derived haplotype",
+      "type": "categorical"
+    },
+    {
+      "key": "cTiter",
+      "title": "Antigenic advance (tree model)",
+      "type": "continuous"
+    },
+    {
+      "key": "cTiterSub",
+      "title": "Antigenic advance (sub model)",
+      "type": "continuous"
+    },
+    {
+      "key": "cTiter_x",
+      "title": "HI antigenic novelty",
+      "type": "continuous"
+    },
+    {
+      "key": "lbi",
+      "title": "Local branching index",
+      "type": "continuous"
+    },
+    {
+      "key": "ep",
+      "title": "Epitope mutations",
+      "type": "continuous"
+    },
+    {
+      "key": "ne",
+      "title": "Non-epitope mutations",
+      "type": "continuous"
+    },
+    {
+      "key": "glyc",
+      "title": "Glycosylation changes",
+      "type": "continuous"
+    },
+    {
+      "key": "region",
+      "title": "Region",
+      "type": "categorical"
+    },
+    {
+      "key": "country",
+      "title": "Country",
+      "type": "categorical"
+    },
+    {
+      "key": "division",
+      "title": "Division",
+      "type": "categorical"
+    },
+    {
+      "key": "accession_ha",
+      "title": "Accession (HA)",
+      "type": "categorical"
+    },
+    {
+      "key": "accession_na",
+      "title": "Accession (NA)",
+      "type": "categorical"
+    },
+    {
+      "key": "submitting_lab",
+      "title": "Submitting lab",
+      "type": "categorical"
+    },
+    {
+      "key": "originating_lab",
+      "title": "Originating lab",
+      "type": "categorical"
+    },
+    {
+      "key": "recency",
+      "title": "Submission date",
+      "type": "ordinal"
+    },
+    {
+      "key": "epiweek",
+      "title": "Epiweek (CDC)",
+      "type": "ordinal"
+    },
+    {
+      "key": "year_month",
+      "title": "Year/month",
+      "type": "categorical"
+    },
+    {
+      "key": "tsne_x",
+      "title": "t-SNE 1",
+      "type": "continuous"
+    },
+    {
+      "key": "tsne_y",
+      "title": "t-SNE 2",
+      "type": "continuous"
+    },
+    {
+      "key": "tsne_cluster",
+      "title": "t-SNE cluster",
+      "type": "categorical"
+    }
+  ],
+  "geo_resolutions": [
+    "division",
+    "country",
+    "region"
+  ],
+  "display_defaults": {
+    "map_triplicate": true,
+    "color_by": "clade_membership"
+  },
+  "filters": [
+    "clade_membership",
+    "subclade",
+    "region",
+    "country",
+    "division",
+    "submitting_lab",
+    "recency",
+    "epiweek",
+    "year_month",
+    "tsne_cluster"
+  ],
+  "panels": [
+    "tree",
+    "map",
+    "entropy",
+    "frequencies"
+  ]
+}
diff --git a/config/h1n1pdm/na/auspice_config.json b/config/h1n1pdm/na/auspice_config.json
new file mode 100644
index 00000000..f3417541
--- /dev/null
+++ b/config/h1n1pdm/na/auspice_config.json
@@ -0,0 +1,208 @@
+{
+  "title": "Real-time tracking of influenza A/H1N1pdm evolution",
+  "maintainers": [
+    {
+      "name": "Jennifer Chang",
+      "url": "https://bedford.io/team/jennifer-chang/"
+    },
+    {
+      "name": "Jover Lee",
+      "url": "https://bedford.io/team/jover-lee/"
+    },
+    {
+      "name": "John Huddleston",
+      "url": "https://bedford.io/team/john-huddleston/"
+    },
+    {
+      "name": "Richard Neher",
+      "url": "https://neherlab.org/richard-neher.html"
+    },
+    {
+      "name": "Trevor Bedford",
+      "url": "https://bedford.io/team/trevor-bedford/"
+    }
+  ],
+  "data_provenance": [
+    {
+      "name": "GISAID"
+    }
+  ],
+  "build_url": "https://github.com/nextstrain/seasonal-flu",
+  "colorings": [
+    {
+      "key": "gt",
+      "title": "Genotype",
+      "type": "categorical"
+    },
+    {
+      "key": "num_date",
+      "title": "Date",
+      "type": "continuous"
+    },
+    {
+      "key": "clade_membership",
+      "title": "Clade",
+      "type": "categorical"
+    },
+    {
+      "key": "subclade",
+      "title": "Subclade",
+      "type": "categorical",
+      "scale": [
+        [
+          "C",
+          "#3E5DD0"
+        ],
+        [
+          "C.3",
+          "#4A8CC2"
+        ],
+        [
+          "C.4",
+          "#60AA9E"
+        ],
+        [
+          "C.5.1.1",
+          "#80B974"
+        ],
+        [
+          "C.5.2",
+          "#A6BE55"
+        ],
+        [
+          "C.5.3",
+          "#CBB742"
+        ],
+        [
+          "C.5.3.1",
+          "#E29D39"
+        ],
+        [
+          "C.5.3.2",
+          "#E56A2F"
+        ],
+        [
+          "C.5.3.3",
+          "#DB2823"
+        ]
+      ]
+    },
+    {
+      "key": "haplotype",
+      "title": "Derived haplotype",
+      "type": "categorical"
+    },
+    {
+      "key": "lbi",
+      "title": "Local branching index",
+      "type": "continuous"
+    },
+    {
+      "key": "ep",
+      "title": "Epitope mutations",
+      "type": "continuous"
+    },
+    {
+      "key": "ne",
+      "title": "Non-epitope mutations",
+      "type": "continuous"
+    },
+    {
+      "key": "glyc",
+      "title": "Glycosylation changes",
+      "type": "continuous"
+    },
+    {
+      "key": "region",
+      "title": "Region",
+      "type": "categorical"
+    },
+    {
+      "key": "country",
+      "title": "Country",
+      "type": "categorical"
+    },
+    {
+      "key": "division",
+      "title": "Division",
+      "type": "categorical"
+    },
+    {
+      "key": "accession_ha",
+      "title": "Accession (HA)",
+      "type": "categorical"
+    },
+    {
+      "key": "accession_na",
+      "title": "Accession (NA)",
+      "type": "categorical"
+    },
+    {
+      "key": "submitting_lab",
+      "title": "Submitting lab",
+      "type": "categorical"
+    },
+    {
+      "key": "originating_lab",
+      "title": "Originating lab",
+      "type": "categorical"
+    },
+    {
+      "key": "recency",
+      "title": "Submission date",
+      "type": "ordinal"
+    },
+    {
+      "key": "epiweek",
+      "title": "Epiweek (CDC)",
+      "type": "ordinal"
+    },
+    {
+      "key": "year_month",
+      "title": "Year/month",
+      "type": "categorical"
+    },
+    {
+      "key": "tsne_x",
+      "title": "t-SNE 1",
+      "type": "continuous"
+    },
+    {
+      "key": "tsne_y",
+      "title": "t-SNE 2",
+      "type": "continuous"
+    },
+    {
+      "key": "tsne_cluster",
+      "title": "t-SNE cluster",
+      "type": "categorical"
+    }
+  ],
+  "geo_resolutions": [
+    "division",
+    "country",
+    "region"
+  ],
+  "display_defaults": {
+    "map_triplicate": true,
+    "color_by": "clade_membership"
+  },
+  "filters": [
+    "clade_membership",
+    "subclade",
+    "region",
+    "country",
+    "division",
+    "submitting_lab",
+    "recency",
+    "epiweek",
+    "year_month",
+    "tsne_cluster"
+  ],
+  "panels": [
+    "tree",
+    "map",
+    "entropy",
+    "frequencies"
+  ]
+}
diff --git a/config/h3n2/ha/auspice_config.json b/config/h3n2/ha/auspice_config.json
new file mode 100644
index 00000000..1d7a787a
--- /dev/null
+++ b/config/h3n2/ha/auspice_config.json
@@ -0,0 +1,221 @@
+{
+  "title": "Real-time tracking of influenza A/H3N2 evolution",
+  "maintainers": [
+    {
+      "name": "Jennifer Chang",
+      "url": "https://bedford.io/team/jennifer-chang/"
+    },
+    {
+      "name": "Jover Lee",
+      "url": "https://bedford.io/team/jover-lee/"
+    },
+    {
+      "name": "John Huddleston",
+      "url": "https://bedford.io/team/john-huddleston/"
+    },
+    {
+      "name": "Richard Neher",
+      "url": "https://neherlab.org/richard-neher.html"
+    },
+    {
+      "name": "Trevor Bedford",
+      "url": "https://bedford.io/team/trevor-bedford/"
+    }
+  ],
+  "data_provenance": [
+    {
+      "name": "GISAID"
+    }
+  ],
+  "build_url": "https://github.com/nextstrain/seasonal-flu",
+  "colorings": [
+    {
+      "key": "gt",
+      "title": "Genotype",
+      "type": "categorical"
+    },
+    {
+      "key": "num_date",
+      "title": "Date",
+      "type": "continuous"
+    },
+    {
+      "key": "clade_membership",
+      "title": "Clade",
+      "type": "categorical"
+    },
+    {
+      "key": "subclade",
+      "title": "Subclade",
+      "type": "categorical",
+      "scale": [
+        [
+          "G.1.3.1",
+          "#447CCD"
+        ],
+        [
+          "J",
+          "#5EA9A1"
+        ],
+        [
+          "J.1",
+          "#8ABB6A"
+        ],
+        [
+          "J.2",
+          "#BEBB48"
+        ],
+        [
+          "J.3",
+          "#E29E39"
+        ],
+        [
+          "J.4",
+          "#E2562B"
+        ]
+      ]
+    },
+    {
+      "key": "haplotype",
+      "title": "Derived haplotype",
+      "type": "categorical"
+    },
+    {
+      "key": "ne_star",
+      "title": "Mutational load",
+      "type": "continuous"
+    },
+    {
+      "key": "cTiter",
+      "title": "Antigenic advance (tree model)",
+      "type": "continuous"
+    },
+    {
+      "key": "cTiterSub",
+      "title": "Antigenic advance (sub model)",
+      "type": "continuous"
+    },
+    {
+      "key": "cTiter_x",
+      "title": "HI antigenic novelty",
+      "type": "continuous"
+    },
+    {
+      "key": "lbi",
+      "title": "Local branching index",
+      "type": "continuous"
+    },
+    {
+      "key": "ep",
+      "title": "Epitope mutations",
+      "type": "continuous"
+    },
+    {
+      "key": "ne",
+      "title": "Non-epitope mutations",
+      "type": "continuous"
+    },
+    {
+      "key": "rb",
+      "title": "RBS adjacent mutations",
+      "type": "continuous"
+    },
+    {
+      "key": "glyc",
+      "title": "Glycosylation changes",
+      "type": "continuous"
+    },
+    {
+      "key": "region",
+      "title": "Region",
+      "type": "categorical"
+    },
+    {
+      "key": "country",
+      "title": "Country",
+      "type": "categorical"
+    },
+    {
+      "key": "division",
+      "title": "Division",
+      "type": "categorical"
+    },
+    {
+      "key": "accession_ha",
+      "title": "Accession (HA)",
+      "type": "categorical"
+    },
+    {
+      "key": "accession_na",
+      "title": "Accession (NA)",
+      "type": "categorical"
+    },
+    {
+      "key": "submitting_lab",
+      "title": "Submitting lab",
+      "type": "categorical"
+    },
+    {
+      "key": "originating_lab",
+      "title": "Originating lab",
+      "type": "categorical"
+    },
+    {
+      "key": "recency",
+      "title": "Submission date",
+      "type": "ordinal"
+    },
+    {
+      "key": "epiweek",
+      "title": "Epiweek (CDC)",
+      "type": "ordinal"
+    },
+    {
+      "key": "year_month",
+      "title": "Year/month",
+      "type": "categorical"
+    },
+    {
+      "key": "tsne_x",
+      "title": "t-SNE 1",
+      "type": "continuous"
+    },
+    {
+      "key": "tsne_y",
+      "title": "t-SNE 2",
+      "type": "continuous"
+    },
+    {
+      "key": "tsne_cluster",
+      "title": "t-SNE cluster",
+      "type": "categorical"
+    }
+  ],
+  "geo_resolutions": [
+    "division",
+    "country",
+    "region"
+  ],
+  "display_defaults": {
+    "map_triplicate": true,
+    "color_by": "clade_membership"
+  },
+  "filters": [
+    "clade_membership",
+    "subclade",
+    "region",
+    "country",
+    "division",
+    "submitting_lab",
+    "recency",
+    "epiweek",
+    "year_month",
+    "tsne_cluster"
+  ],
+  "panels": [
+    "tree",
+    "map",
+    "entropy",
+    "frequencies"
+  ]
+}
diff --git a/config/h3n2/na/auspice_config.json b/config/h3n2/na/auspice_config.json
new file mode 100644
index 00000000..5cc55ded
--- /dev/null
+++ b/config/h3n2/na/auspice_config.json
@@ -0,0 +1,193 @@
+{
+  "title": "Real-time tracking of influenza A/H3N2 evolution",
+  "maintainers": [
+    {
+      "name": "Jennifer Chang",
+      "url": "https://bedford.io/team/jennifer-chang/"
+    },
+    {
+      "name": "Jover Lee",
+      "url": "https://bedford.io/team/jover-lee/"
+    },
+    {
+      "name": "John Huddleston",
+      "url": "https://bedford.io/team/john-huddleston/"
+    },
+    {
+      "name": "Richard Neher",
+      "url": "https://neherlab.org/richard-neher.html"
+    },
+    {
+      "name": "Trevor Bedford",
+      "url": "https://bedford.io/team/trevor-bedford/"
+    }
+  ],
+  "data_provenance": [
+    {
+      "name": "GISAID"
+    }
+  ],
+  "build_url": "https://github.com/nextstrain/seasonal-flu",
+  "colorings": [
+    {
+      "key": "gt",
+      "title": "Genotype",
+      "type": "categorical"
+    },
+    {
+      "key": "num_date",
+      "title": "Date",
+      "type": "continuous"
+    },
+    {
+      "key": "clade_membership",
+      "title": "Clade",
+      "type": "categorical"
+    },
+    {
+      "key": "subclade",
+      "title": "Subclade",
+      "type": "categorical",
+      "scale": [
+        [
+          "B.4",
+          "#4A8CC2"
+        ],
+        [
+          "B.4.1",
+          "#71B486"
+        ],
+        [
+          "B.4.2",
+          "#ABBD52"
+        ],
+        [
+          "B.4.3",
+          "#DEA73C"
+        ]
+      ]
+    },
+    {
+      "key": "haplotype",
+      "title": "Derived haplotype",
+      "type": "categorical"
+    },
+    {
+      "key": "ne_star",
+      "title": "Mutational load",
+      "type": "continuous"
+    },
+    {
+      "key": "lbi",
+      "title": "Local branching index",
+      "type": "continuous"
+    },
+    {
+      "key": "ep",
+      "title": "Epitope mutations",
+      "type": "continuous"
+    },
+    {
+      "key": "ne",
+      "title": "Non-epitope mutations",
+      "type": "continuous"
+    },
+    {
+      "key": "glyc",
+      "title": "Glycosylation changes",
+      "type": "continuous"
+    },
+    {
+      "key": "region",
+      "title": "Region",
+      "type": "categorical"
+    },
+    {
+      "key": "country",
+      "title": "Country",
+      "type": "categorical"
+    },
+    {
+      "key": "division",
+      "title": "Division",
+      "type": "categorical"
+    },
+    {
+      "key": "accession_ha",
+      "title": "Accession (HA)",
+      "type": "categorical"
+    },
+    {
+      "key": "accession_na",
+      "title": "Accession (NA)",
+      "type": "categorical"
+    },
+    {
+      "key": "submitting_lab",
+      "title": "Submitting lab",
+      "type": "categorical"
+    },
+    {
+      "key": "originating_lab",
+      "title": "Originating lab",
+      "type": "categorical"
+    },
+    {
+      "key": "recency",
+      "title": "Submission date",
+      "type": "ordinal"
+    },
+    {
+      "key": "epiweek",
+      "title": "Epiweek (CDC)",
+      "type": "ordinal"
+    },
+    {
+      "key": "year_month",
+      "title": "Year/month",
+      "type": "categorical"
+    },
+    {
+      "key": "tsne_x",
+      "title": "t-SNE 1",
+      "type": "continuous"
+    },
+    {
+      "key": "tsne_y",
+      "title": "t-SNE 2",
+      "type": "continuous"
+    },
+    {
+      "key": "tsne_cluster",
+      "title": "t-SNE cluster",
+      "type": "categorical"
+    }
+  ],
+  "geo_resolutions": [
+    "division",
+    "country",
+    "region"
+  ],
+  "display_defaults": {
+    "map_triplicate": true,
+    "color_by": "clade_membership"
+  },
+  "filters": [
+    "clade_membership",
+    "subclade",
+    "region",
+    "country",
+    "division",
+    "submitting_lab",
+    "recency",
+    "epiweek",
+    "year_month",
+    "tsne_cluster"
+  ],
+  "panels": [
+    "tree",
+    "map",
+    "entropy",
+    "frequencies"
+  ]
+}
diff --git a/config/vic/ha/auspice_config.json b/config/vic/ha/auspice_config.json
new file mode 100644
index 00000000..e2fccd11
--- /dev/null
+++ b/config/vic/ha/auspice_config.json
@@ -0,0 +1,200 @@
+{
+  "title": "Real-time tracking of influenza B/Vic evolution",
+  "maintainers": [
+    {
+      "name": "Jennifer Chang",
+      "url": "https://bedford.io/team/jennifer-chang/"
+    },
+    {
+      "name": "Jover Lee",
+      "url": "https://bedford.io/team/jover-lee/"
+    },
+    {
+      "name": "John Huddleston",
+      "url": "https://bedford.io/team/john-huddleston/"
+    },
+    {
+      "name": "Richard Neher",
+      "url": "https://neherlab.org/richard-neher.html"
+    },
+    {
+      "name": "Trevor Bedford",
+      "url": "https://bedford.io/team/trevor-bedford/"
+    }
+  ],
+  "data_provenance": [
+    {
+      "name": "GISAID"
+    }
+  ],
+  "build_url": "https://github.com/nextstrain/seasonal-flu",
+  "colorings": [
+    {
+      "key": "gt",
+      "title": "Genotype",
+      "type": "categorical"
+    },
+    {
+      "key": "num_date",
+      "title": "Date",
+      "type": "continuous"
+    },
+    {
+      "key": "clade_membership",
+      "title": "Clade",
+      "type": "categorical"
+    },
+    {
+      "key": "subclade",
+      "title": "Subclade",
+      "type": "categorical",
+      "scale": [
+        [
+          "C.2",
+          "#4272CE"
+        ],
+        [
+          "C.3",
+          "#58A2AC"
+        ],
+        [
+          "C.5",
+          "#7DB877"
+        ],
+        [
+          "C.5.1",
+          "#AEBD50"
+        ],
+        [
+          "C.5.4",
+          "#D8AE3E"
+        ],
+        [
+          "C.5.6",
+          "#E67A32"
+        ],
+        [
+          "C.5.7",
+          "#DB2823"
+        ]
+      ]
+    },
+    {
+      "key": "cTiter",
+      "title": "Antigenic advance (tree model)",
+      "type": "continuous"
+    },
+    {
+      "key": "cTiterSub",
+      "title": "Antigenic advance (sub model)",
+      "type": "continuous"
+    },
+    {
+      "key": "cTiter_x",
+      "title": "HI antigenic novelty",
+      "type": "continuous"
+    },
+    {
+      "key": "lbi",
+      "title": "Local branching index",
+      "type": "continuous"
+    },
+    {
+      "key": "glyc",
+      "title": "Glycosylation changes",
+      "type": "continuous"
+    },
+    {
+      "key": "region",
+      "title": "Region",
+      "type": "categorical"
+    },
+    {
+      "key": "country",
+      "title": "Country",
+      "type": "categorical"
+    },
+     {
+      "key": "division",
+      "title": "Division",
+      "type": "categorical"
+    },
+    {
+      "key": "accession_ha",
+      "title": "Accession (HA)",
+      "type": "categorical"
+    },
+    {
+      "key": "accession_na",
+      "title": "Accession (NA)",
+      "type": "categorical"
+    },
+    {
+      "key": "submitting_lab",
+      "title": "Submitting lab",
+      "type": "categorical"
+    },
+    {
+      "key": "originating_lab",
+      "title": "Originating lab",
+      "type": "categorical"
+    },
+    {
+      "key": "recency",
+      "title": "Submission date",
+      "type": "ordinal"
+    },
+    {
+      "key": "epiweek",
+      "title": "Epiweek (CDC)",
+      "type": "ordinal"
+    },
+    {
+      "key": "year_month",
+      "title": "Year/month",
+      "type": "categorical"
+    },
+    {
+      "key": "tsne_x",
+      "title": "t-SNE 1",
+      "type": "continuous"
+    },
+    {
+      "key": "tsne_y",
+      "title": "t-SNE 2",
+      "type": "continuous"
+    },
+    {
+      "key": "tsne_cluster",
+      "title": "t-SNE cluster",
+      "type": "categorical"
+    }
+  ],
+  "geo_resolutions": [
+    "division",
+    "country",
+    "region"
+  ],
+  "display_defaults": {
+    "map_triplicate": true,
+    "color_by": "clade_membership"
+  },
+  "filters": [
+    "clade_membership",
+    "subclade",
+    "region",
+    "country",
+    "division",
+    "submitting_lab",
+    "recency",
+    "epiweek",
+    "year_month",
+    "tsne_cluster"
+  ],
+  "panels": [
+    "tree",
+    "map",
+    "entropy",
+    "frequencies"
+  ]
+}
diff --git a/config/vic/na/auspice_config.json b/config/vic/na/auspice_config.json
new file mode 100644
index 00000000..f877353a
--- /dev/null
+++ b/config/vic/na/auspice_config.json
@@ -0,0 +1,193 @@
+{
+  "title": "Real-time tracking of influenza B/Vic evolution",
+  "maintainers": [
+    {
+      "name": "Jennifer Chang",
+      "url": "https://bedford.io/team/jennifer-chang/"
+    },
+    {
+      "name": "Jover Lee",
+      "url": "https://bedford.io/team/jover-lee/"
+    },
+    {
+      "name": "John Huddleston",
+      "url": "https://bedford.io/team/john-huddleston/"
+    },
+    {
+      "name": "Richard Neher",
+      "url": "https://neherlab.org/richard-neher.html"
+    },
+    {
+      "name": "Trevor Bedford",
+      "url": "https://bedford.io/team/trevor-bedford/"
+    }
+  ],
+  "data_provenance": [
+    {
+      "name": "GISAID"
+    }
+  ],
+  "build_url": "https://github.com/nextstrain/seasonal-flu",
+  "colorings": [
+    {
+      "key": "gt",
+      "title": "Genotype",
+      "type": "categorical"
+    },
+    {
+      "key": "num_date",
+      "title": "Date",
+      "type": "continuous"
+    },
+    {
+      "key": "clade_membership",
+      "title": "Clade",
+      "type": "categorical"
+    },
+    {
+      "key": "subclade",
+      "title": "Subclade",
+      "type": "categorical",
+      "scale": [
+        [
+          "B",
+          "#3E5DD0"
+        ],
+        [
+          "B.3",
+          "#4A8CC2"
+        ],
+        [
+          "B.5",
+          "#60AA9E"
+        ],
+        [
+          "B.6",
+          "#80B974"
+        ],
+        [
+          "B.7",
+          "#A6BE55"
+        ],
+        [
+          "B.7.1",
+          "#CBB742"
+        ],
+        [
+          "B.7.2",
+          "#E29D39"
+        ],
+        [
+          "B.7.3",
+          "#E56A2F"
+        ],
+        [
+          "B.8",
+          "#DB2823"
+        ]
+      ]
+    },
+    {
+      "key": "lbi",
+      "title": "Local branching index",
+      "type": "continuous"
+    },
+    {
+      "key": "glyc",
+      "title": "Glycosylation changes",
+      "type": "continuous"
+    },
+    {
+      "key": "region",
+      "title": "Region",
+      "type": "categorical"
+    },
+    {
+      "key": "country",
+      "title": "Country",
+      "type": "categorical"
+    },
+     {
+      "key": "division",
+      "title": "Division",
+      "type": "categorical"
+    },
+    {
+      "key": "accession_ha",
+      "title": "Accession (HA)",
+      "type": "categorical"
+    },
+    {
+      "key": "accession_na",
+      "title": "Accession (NA)",
+      "type": "categorical"
+    },
+    {
+      "key": "submitting_lab",
+      "title": "Submitting lab",
+      "type": "categorical"
+    },
+    {
+      "key": "originating_lab",
+      "title": "Originating lab",
+      "type": "categorical"
+    },
+    {
+      "key": "recency",
+      "title": "Submission date",
+      "type": "ordinal"
+    },
+    {
+      "key": "epiweek",
+      "title": "Epiweek (CDC)",
+      "type": "ordinal"
+    },
+    {
+      "key": "year_month",
+      "title": "Year/month",
+      "type": "categorical"
+    },
+    {
+      "key": "tsne_x",
+      "title": "t-SNE 1",
+      "type": "continuous"
+    },
+    {
+      "key": "tsne_y",
+      "title": "t-SNE 2",
+      "type": "continuous"
+    },
+    {
+      "key": "tsne_cluster",
+      "title": "t-SNE cluster",
+      "type": "categorical"
+    }
+  ],
+  "geo_resolutions": [
+    "division",
+    "country",
+    "region"
+  ],
+  "display_defaults": {
+    "map_triplicate": true,
+    "color_by": "clade_membership"
+  },
+  "filters": [
+    "clade_membership",
+    "subclade",
+    "region",
+    "country",
+    "division",
+    "submitting_lab",
+    "recency",
+    "epiweek",
+    "year_month",
+    "tsne_cluster"
+  ],
+  "panels": [
+    "tree",
+    "map",
+    "entropy",
+    "frequencies"
+  ]
+}
diff --git a/profiles/nextflu-private.yaml b/profiles/nextflu-private.yaml
index 7763ba59..7fb770b0 100644
--- a/profiles/nextflu-private.yaml
+++ b/profiles/nextflu-private.yaml
@@ -169,101 +169,11 @@ builds:
         data: "data/vic/who_ferret_egg_hi_titers.tsv"
         prefix: egg_hi_
         title: "Egg-passaged HI titers from ferret sera"
-    subsamples: *titers-subsampling-scheme
-  # Define builds with representative sampling for cases when we need to
-  # minimize sampling bias (e.g., LBI, tree topology, frequencies, etc.).
-  h1n1pdm_2y:
-    lineage: "h1n1pdm"
-    reference: "config/h1n1pdm/{segment}/reference.fasta"
-    annotation: "config/h1n1pdm/{segment}/genemap.gff"
-    tree_exclude_sites: "config/h1n1pdm/{segment}/exclude-sites.txt"
-    clades: "config/h1n1pdm/ha/clades.tsv"
-    subclades: "config/h1n1pdm/{segment}/subclades.tsv"
-    auspice_config: "profiles/nextflu-private/h1n1pdm/{segment}/auspice_config.json"
-    vaccines: "config/h1n1pdm/vaccine.json"
-    enable_glycosylation: true
-    enable_lbi: true
-    enable_titer_models: true
-    enable_measurements: true
-    enable_embeddings: true
-    min_date: "2Y"
-    reference_min_date: "6Y"
-    max_date: "4W"
-    include: "config/h1n1pdm/reference_strains.txt"
-    exclude: "config/h1n1pdm/outliers.txt"
-    titer_collections:
-      - name: cell_hi
-        data: "data/h1n1pdm/who_ferret_cell_hi_titers.tsv"
-        prefix: cell_hi_
-        title: "Cell-passaged HI titers from ferret sera"
-    subsamples: &representative-subsampling-scheme
-      regions_except_europe:
-          filters: --query "(passage_category != 'egg') & (region != 'Europe') & (ha == True) & (na == True)" --group-by region year month --subsample-max-sequences 2700 --min-date {min_date} --exclude {exclude}
-          priorities: "titers"
-      europe:
-          filters: --query "(passage_category != 'egg') & (region == 'Europe') & (ha == True) & (na == True)" --group-by country year month --subsample-max-sequences 300 --min-date {min_date} --exclude {exclude}
-          priorities: "titers"
-      references:
-          filters: --query "(is_reference == True)" --min-date {reference_min_date}
-  h3n2_2y:
-    lineage: "h3n2"
-    reference: "config/h3n2/{segment}/reference.fasta"
-    annotation: "config/h3n2/{segment}/genemap.gff"
-    tree_exclude_sites: "config/h3n2/{segment}/exclude-sites.txt"
-    clades: "config/h3n2/ha/clades.tsv"
-    subclades: "config/h3n2/{segment}/subclades.tsv"
-    auspice_config: "profiles/nextflu-private/h3n2/{segment}/auspice_config.json"
-    vaccines: "config/h3n2/vaccine.json"
-    enable_glycosylation: true
-    enable_lbi: true
-    enable_forecasts: true
-    enable_titer_models: true
-    enable_measurements: true
-    enable_embeddings: true
-    min_date: "2Y"
-    reference_min_date: "6Y"
-    max_date: "4W"
-    include: "config/h3n2/reference_strains.txt"
-    exclude: "config/h3n2/outliers.txt"
-    titer_collections:
-      - name: cell_fra
-        data: "data/h3n2/who_ferret_cell_fra_titers.tsv"
-        prefix: cell_fra_
-        title: "Cell-passaged FRA titers from ferret sera"
-      - name: human_cell_fra
-        data: "data/h3n2/who_human_cell_fra_titers.tsv"
-        prefix: human_cell_fra_
-        title: "Cell-passaged FRA titers from pooled human sera"
-    subsamples: *representative-subsampling-scheme
-  vic_2y:
-    lineage: "vic"
-    reference: "config/vic/{segment}/reference.fasta"
-    annotation: "config/vic/{segment}/genemap.gff"
-    tree_exclude_sites: "config/vic/{segment}/exclude-sites.txt"
-    clades: "config/vic/ha/clades.tsv"
-    subclades: "config/vic/{segment}/subclades.tsv"
-    auspice_config: "profiles/nextflu-private/vic/{segment}/auspice_config.json"
-    vaccines: "config/vic/vaccine.json"
-    enable_glycosylation: true
-    enable_lbi: true
-    enable_titer_models: true
-    enable_measurements: true
-    enable_embeddings: true
-    min_date: "2Y"
-    reference_min_date: "6Y"
-    max_date: "4W"
-    include: "config/vic/reference_strains.txt"
-    exclude: "config/vic/outliers.txt"
-    titer_collections:
-      - name: cell_hi
-        data: "data/vic/who_ferret_cell_hi_titers.tsv"
-        prefix: cell_hi_
-        title: "Cell-passaged HI titers from ferret sera"
       - name: human_cell_hi
         data: "data/vic/who_human_cell_hi_titers.tsv"
         prefix: human_cell_hi_
         title: "Cell-passaged HI titers from pooled human sera"
-    subsamples: *representative-subsampling-scheme
+    subsamples: *titers-subsampling-scheme
 
 fitness_model:
   models:
diff --git a/profiles/nextstrain-public.yaml b/profiles/nextstrain-public.yaml
index efc5d5d4..dd124154 100644
--- a/profiles/nextstrain-public.yaml
+++ b/profiles/nextstrain-public.yaml
@@ -97,7 +97,24 @@ array-builds:
       resolution:
         - 2y
     build_name: "seasonal-flu_{lineage}_2y"
-    build_params: *shared-hi-build-params
+    build_params:
+      auspice_name: "seasonal-flu_{lineage}_{{segment}}_{resolution}"
+      reference: "config/{lineage}/{{segment}}/reference.fasta"
+      annotation: "config/{lineage}/{{segment}}/genemap.gff"
+      tree_exclude_sites: "config/{lineage}/{{segment}}/exclude-sites.txt"
+      clades: "config/{lineage}/ha/clades.tsv"
+      subclades: "config/{lineage}/{{segment}}/subclades.tsv"
+      auspice_config: "config/{lineage}/{{segment}}/auspice_config.json"
+      vaccines: "config/{lineage}/vaccine.json"
+      enable_glycosylation: true
+      enable_lbi: true
+      enable_titer_models: true
+      enable_embeddings: true
+      include: "'config/{lineage}/reference_strains.txt'"
+      exclude: "'config/{lineage}/outliers.txt'"
+      titer_collections:
+        - name: cdc_cell_hi
+          data: "data/{lineage}/cdc_ferret_cell_hi_titers.tsv"
     subsamples: *subsampling-scheme
   3Y-hi-builds:
     patterns:
@@ -188,7 +205,7 @@ array-builds:
       tree_exclude_sites: "config/{lineage}/{{segment}}/exclude-sites.txt"
       clades: "config/{lineage}/ha/clades.tsv"
       subclades: "config/{lineage}/{{segment}}/subclades.tsv"
-      auspice_config: "config/{lineage}/auspice_config.json"
+      auspice_config: "config/{lineage}/{{segment}}/auspice_config.json"
       vaccines: "config/{lineage}/vaccine.json"
       enable_glycosylation: true
       enable_lbi: true